PMC:1186732 / 48022-48305 JSONTXT

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    craft-sa-dev

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It is possible that there are gene regulatory differences between mice and humans such that in human NR2E3 mutants, S-opsin shows a type I pattern of derepression rather than a type II as in seen in the rd7 mouse, and is therefore expressed in all of the hybrid photoreceptor cells."}

    craft-ca-core-ex-dev

    {"project":"craft-ca-core-ex-dev","denotations":[{"id":"T8291","span":{"begin":31,"end":35},"obj":"SO_EXT:0000704"},{"id":"T8292","span":{"begin":36,"end":46},"obj":"GO:0065007"},{"id":"T8293","span":{"begin":67,"end":71},"obj":"NCBITaxon:10088"},{"id":"T8294","span":{"begin":76,"end":82},"obj":"NCBITaxon:9606"},{"id":"T8295","span":{"begin":96,"end":101},"obj":"NCBITaxon:9606"},{"id":"T8296","span":{"begin":102,"end":107},"obj":"PR_EXT:000011403"},{"id":"T8297","span":{"begin":108,"end":115},"obj":"SO_EXT:sequence_altered_entity"},{"id":"T8298","span":{"begin":117,"end":124},"obj":"PR_EXT:000001195"},{"id":"T8299","span":{"begin":208,"end":213},"obj":"NCBITaxon:10088"},{"id":"T8300","span":{"begin":232,"end":241},"obj":"GO:0010467"},{"id":"T8301","span":{"begin":263,"end":282},"obj":"CL:0000210"},{"id":"T8302","span":{"begin":277,"end":282},"obj":"CL_GO_EXT:cell"}],"text":" It is possible that there are gene regulatory differences between mice and humans such that in human NR2E3 mutants, S-opsin shows a type I pattern of derepression rather than a type II as in seen in the rd7 mouse, and is therefore expressed in all of the hybrid photoreceptor cells."}

    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T7723","span":{"begin":31,"end":35},"obj":"SO:0000704"},{"id":"T7724","span":{"begin":36,"end":46},"obj":"GO:0065007"},{"id":"T7725","span":{"begin":67,"end":71},"obj":"NCBITaxon:10088"},{"id":"T7726","span":{"begin":76,"end":82},"obj":"NCBITaxon:9606"},{"id":"T7727","span":{"begin":96,"end":101},"obj":"NCBITaxon:9606"},{"id":"T7728","span":{"begin":102,"end":107},"obj":"PR:000011403"},{"id":"T7729","span":{"begin":117,"end":124},"obj":"PR:000001195"},{"id":"T7730","span":{"begin":208,"end":213},"obj":"NCBITaxon:10088"},{"id":"T7731","span":{"begin":232,"end":241},"obj":"GO:0010467"},{"id":"T7732","span":{"begin":263,"end":282},"obj":"CL:0000210"}],"text":" It is possible that there are gene regulatory differences between mice and humans such that in human NR2E3 mutants, S-opsin shows a type I pattern of derepression rather than a type II as in seen in the rd7 mouse, and is therefore expressed in all of the hybrid photoreceptor cells."}