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PMC:1186732 / 44052-44963 JSONTXT

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Id Subject Object Predicate Lexical cue
T10298 0-3 CD denotes One
T10299 58-61 VBD denotes was
T10300 4-6 IN denotes of
T10301 7-10 DT denotes the
T10302 24-32 NNS denotes findings
T10303 11-15 RBS denotes most
T10304 16-23 JJ denotes curious
T10305 33-35 IN denotes in
T10306 36-39 DT denotes the
T10307 51-57 NN denotes retina
T10308 40-43 NN denotes rd7
T10309 44-50 NN denotes mutant
T10310 62-65 DT denotes the
T10311 66-76 NN denotes occurrence
T10312 77-79 IN denotes of
T10313 80-83 CD denotes two
T10314 94-99 NNS denotes types
T10315 84-93 JJ denotes different
T10316 100-102 IN denotes of
T10317 103-110 NNS denotes changes
T10318 110-112 : denotes :
T10319 112-114 DT denotes an
T10320 115-123 NN denotes increase
T10321 124-126 IN denotes in
T10322 127-130 DT denotes the
T10323 131-137 NN denotes number
T10324 138-140 IN denotes of
T10325 141-142 NN denotes S
T10326 143-148 NN denotes opsin
T10327 142-143 HYPH denotes -
T10328 149-159 VBG denotes expressing
T10329 148-149 HYPH denotes –
T10330 160-165 NNS denotes cones
T10331 166-169 CC denotes and
T10332 170-171 DT denotes a
T10333 172-186 NN denotes transformation
T10334 187-189 IN denotes of
T10335 190-194 NNS denotes rods
T10336 195-199 IN denotes into
T10337 200-206 NN denotes hybrid
T10338 207-221 NNS denotes photoreceptors
T10339 221-222 . denotes .
T10340 222-374 sentence denotes It is known that Nr2e3 is expressed only in rods, and the transcript is first detectable in postmitotic cells (J. Trimarchi and CLC, unpublished data).
T10341 223-225 PRP denotes It
T10342 229-234 VBN denotes known
T10343 226-228 VBZ denotes is
T10344 235-239 IN denotes that
T10345 249-258 VBN denotes expressed
T10346 240-245 NN denotes Nr2e3
T10347 246-248 VBZ denotes is
T10348 259-263 RB denotes only
T10349 264-266 IN denotes in
T10350 267-271 NNS denotes rods
T10351 271-273 , denotes ,
T10352 273-276 CC denotes and
T10353 277-280 DT denotes the
T10354 281-291 NN denotes transcript
T10355 292-294 VBZ denotes is
T10356 295-300 RB denotes first
T10357 301-311 JJ denotes detectable
T10358 312-314 IN denotes in
T10359 315-326 JJ denotes postmitotic
T10360 327-332 NNS denotes cells
T10361 333-334 -LRB- denotes (
T10362 334-336 NNP denotes J.
T10363 337-346 NNP denotes Trimarchi
T10364 347-350 CC denotes and
T10365 351-354 NNP denotes CLC
T10366 354-356 , denotes ,
T10367 356-367 JJ denotes unpublished
T10368 368-372 NNS denotes data
T10369 372-373 -RRB- denotes )
T10370 373-374 . denotes .
T10371 374-627 sentence denotes Assuming that Nr2e3 acts cell autonomously, we can conclude that the supernumerary S-cone–positive cells and the hybrid photoreceptors identified in the rd7 retina were redirected to these fates from postmitotic cells that were destined to become rods.
T10372 375-383 VBG denotes Assuming
T10373 426-434 VB denotes conclude
T10374 384-388 IN denotes that
T10375 395-399 VBZ denotes acts
T10376 389-394 NN denotes Nr2e3
T10377 400-404 NN denotes cell
T10378 405-417 RB denotes autonomously
T10379 417-419 , denotes ,
T10380 419-421 PRP denotes we
T10381 422-425 MD denotes can
T10382 435-439 IN denotes that
T10383 544-554 VBN denotes redirected
T10384 440-443 DT denotes the
T10385 474-479 NNS denotes cells
T10386 444-457 JJ denotes supernumerary
T10387 458-459 NN denotes S
T10388 460-464 NN denotes cone
T10389 459-460 HYPH denotes -
T10390 465-473 JJ denotes positive
T10391 464-465 HYPH denotes –
T10392 480-483 CC denotes and
T10393 484-487 DT denotes the
T10394 495-509 NNS denotes photoreceptors
T10395 488-494 NN denotes hybrid
T10396 510-520 VBN denotes identified
T10397 521-523 IN denotes in
T10398 524-527 DT denotes the
T10399 532-538 NN denotes retina
T10400 528-531 NN denotes rd7
T10401 539-543 VBD denotes were
T10402 555-557 IN denotes to
T10403 558-563 DT denotes these
T10404 564-569 NNS denotes fates
T10405 570-574 IN denotes from
T10406 575-586 JJ denotes postmitotic
T10407 587-592 NNS denotes cells
T10408 593-597 WDT denotes that
T10409 603-611 VBN denotes destined
T10410 598-602 VBD denotes were
T10411 612-614 TO denotes to
T10412 615-621 VB denotes become
T10413 622-626 NNS denotes rods
T10414 626-627 . denotes .
T10415 627-843 sentence denotes This conclusion raises this question: Why does loss of a single transcription factor within rod precursors lead to two alternative fates—a hybrid cell type on the one hand and apparently normal S-cones on the other?
T10416 628-632 DT denotes This
T10417 633-643 NN denotes conclusion
T10418 644-650 VBZ denotes raises
T10419 651-655 DT denotes this
T10420 656-664 NN denotes question
T10421 664-666 : denotes :
T10422 666-669 WRB denotes Why
T10423 735-739 VB denotes lead
T10424 670-674 VBZ denotes does
T10425 675-679 NN denotes loss
T10426 680-682 IN denotes of
T10427 683-684 DT denotes a
T10428 706-712 NN denotes factor
T10429 685-691 JJ denotes single
T10430 692-705 NN denotes transcription
T10431 713-719 IN denotes within
T10432 720-723 NN denotes rod
T10433 724-734 NNS denotes precursors
T10434 740-742 IN denotes to
T10435 743-746 CD denotes two
T10436 759-764 NNS denotes fates
T10437 747-758 JJ denotes alternative
T10438 764-765 : denotes —
T10439 765-766 DT denotes a
T10440 779-783 NN denotes type
T10441 767-773 NN denotes hybrid
T10442 774-778 NN denotes cell
T10443 784-786 IN denotes on
T10444 787-790 DT denotes the
T10445 795-799 NN denotes hand
T10446 791-794 CD denotes one
T10447 800-803 CC denotes and
T10448 804-814 RB denotes apparently
T10449 815-821 JJ denotes normal
T10450 824-829 NNS denotes cones
T10451 822-823 NN denotes S
T10452 823-824 HYPH denotes -
T10453 830-832 IN denotes on
T10454 833-836 DT denotes the
T10455 837-842 JJ denotes other
T10456 842-843 . denotes ?
T10457 843-911 sentence denotes There are at least two possible explanations for these differences.
T10458 844-849 EX denotes There
T10459 850-853 VBP denotes are
T10460 854-856 RB denotes at
T10461 857-862 RBS denotes least
T10462 863-866 CD denotes two
T10463 876-888 NNS denotes explanations
T10464 867-875 JJ denotes possible
T10465 889-892 IN denotes for
T10466 893-898 DT denotes these
T10467 899-910 NNS denotes differences
T10468 910-911 . denotes .
R6370 T10337 T10338 compound hybrid,photoreceptors
R6376 T10338 T10336 pobj photoreceptors,into
R6382 T10339 T10299 punct .,was
R6385 T10341 T10342 nsubjpass It,known
R6388 T10343 T10342 auxpass is,known
R6393 T10344 T10345 mark that,expressed
R6397 T10345 T10342 ccomp expressed,known
R6398 T10298 T10299 nsubj One,was
R6399 T10346 T10345 nsubjpass Nr2e3,expressed
R6400 T10300 T10298 prep of,One
R6401 T10301 T10302 det the,findings
R6402 T10347 T10345 auxpass is,expressed
R6403 T10302 T10300 pobj findings,of
R6404 T10303 T10304 advmod most,curious
R6405 T10348 T10349 advmod only,in
R6406 T10304 T10302 amod curious,findings
R6407 T10305 T10298 prep in,One
R6408 T10306 T10307 det the,retina
R6409 T10349 T10345 prep in,expressed
R6410 T10307 T10305 pobj retina,in
R6411 T10308 T10309 compound rd7,mutant
R6412 T10350 T10349 pobj rods,in
R6413 T10309 T10307 compound mutant,retina
R6414 T10310 T10311 det the,occurrence
R6415 T10351 T10345 punct ", ",expressed
R6416 T10311 T10299 attr occurrence,was
R6417 T10312 T10311 prep of,occurrence
R6418 T10313 T10314 nummod two,types
R6419 T10352 T10345 cc and,expressed
R6420 T10314 T10312 pobj types,of
R6421 T10315 T10314 amod different,types
R6422 T10316 T10314 prep of,types
R6423 T10317 T10316 pobj changes,of
R6424 T10353 T10354 det the,transcript
R6425 T10318 T10314 punct : ,types
R6426 T10319 T10320 det an,increase
R6427 T10354 T10355 nsubj transcript,is
R6428 T10320 T10314 appos increase,types
R6429 T10321 T10320 prep in,increase
R6430 T10322 T10323 det the,number
R6431 T10323 T10321 pobj number,in
R6432 T10324 T10323 prep of,number
R6433 T10325 T10326 compound S,opsin
R6434 T10355 T10345 conj is,expressed
R6435 T10326 T10328 npadvmod opsin,expressing
R6436 T10327 T10326 punct -,opsin
R6437 T10328 T10330 amod expressing,cones
R6438 T10356 T10355 advmod first,is
R6439 T10329 T10328 punct –,expressing
R6440 T10330 T10324 pobj cones,of
R6441 T10331 T10320 cc and,increase
R6442 T10357 T10355 acomp detectable,is
R6443 T10332 T10333 det a,transformation
R6444 T10333 T10320 conj transformation,increase
R6445 T10334 T10333 prep of,transformation
R6446 T10358 T10355 prep in,is
R6447 T10335 T10334 pobj rods,of
R6448 T10336 T10333 prep into,transformation
R6449 T10359 T10360 amod postmitotic,cells
R6450 T10360 T10358 pobj cells,in
R6451 T10361 T10362 punct (,J.
R6452 T10443 T10440 prep on,type
R6453 T10362 T10342 meta J.,known
R6454 T10444 T10445 det the,hand
R6455 T10445 T10443 pobj hand,on
R6456 T10363 T10362 nmod Trimarchi,J.
R6457 T10446 T10445 nummod one,hand
R6458 T10447 T10440 cc and,type
R6459 T10448 T10449 advmod apparently,normal
R6460 T10364 T10362 cc and,J.
R6461 T10449 T10450 amod normal,cones
R6462 T10450 T10440 conj cones,type
R6463 T10365 T10362 conj CLC,J.
R6464 T10451 T10450 compound S,cones
R6465 T10452 T10450 punct -,cones
R6466 T10453 T10450 prep on,cones
R6467 T10366 T10365 punct ", ",CLC
R6468 T10454 T10455 det the,other
R6469 T10455 T10453 pobj other,on
R6470 T10367 T10368 amod unpublished,data
R6471 T10368 T10365 conj data,CLC
R6472 T10456 T10418 punct ?,raises
R6473 T10369 T10368 punct ),data
R6474 T10458 T10459 expl There,are
R6475 T10370 T10342 punct .,known
R6476 T10460 T10461 advmod at,least
R6477 T10372 T10373 advcl Assuming,conclude
R6478 T10461 T10462 advmod least,two
R6479 T10462 T10463 nummod two,explanations
R6480 T10463 T10459 attr explanations,are
R6481 T10464 T10463 amod possible,explanations
R6482 T10465 T10463 prep for,explanations
R6483 T10466 T10467 det these,differences
R6484 T10467 T10465 pobj differences,for
R6485 T10374 T10375 mark that,acts
R6486 T10468 T10459 punct .,are
R6488 T10375 T10372 ccomp acts,Assuming
R6491 T10376 T10375 nsubj Nr2e3,acts
R6494 T10377 T10378 npadvmod cell,autonomously
R6498 T10378 T10375 advmod autonomously,acts
R6502 T10379 T10373 punct ", ",conclude
R6506 T10380 T10373 nsubj we,conclude
R6509 T10381 T10373 aux can,conclude
R6513 T10382 T10383 mark that,redirected
R6516 T10383 T10373 ccomp redirected,conclude
R6521 T10384 T10385 det the,cells
R6525 T10385 T10383 nsubjpass cells,redirected
R6529 T10386 T10385 amod supernumerary,cells
R6533 T10387 T10388 compound S,cone
R6537 T10388 T10390 npadvmod cone,positive
R6542 T10389 T10388 punct -,cone
R6545 T10390 T10385 amod positive,cells
R6549 T10391 T10390 punct –,positive
R6552 T10392 T10385 cc and,cells
R6556 T10393 T10394 det the,photoreceptors
R6560 T10394 T10385 conj photoreceptors,cells
R6563 T10395 T10394 compound hybrid,photoreceptors
R6567 T10396 T10385 acl identified,cells
R6570 T10397 T10396 prep in,identified
R6574 T10398 T10399 det the,retina
R6576 T10399 T10397 pobj retina,in
R6579 T10400 T10399 compound rd7,retina
R6582 T10401 T10383 auxpass were,redirected
R6584 T10402 T10383 prep to,redirected
R6586 T10403 T10404 det these,fates
R6590 T10404 T10402 pobj fates,to
R6592 T10405 T10383 prep from,redirected
R6596 T10406 T10407 amod postmitotic,cells
R6599 T10407 T10405 pobj cells,from
R6602 T10408 T10409 dep that,destined
R6606 T10409 T10407 relcl destined,cells
R6609 T10410 T10409 auxpass were,destined
R6613 T10411 T10412 aux to,become
R6618 T10412 T10409 xcomp become,destined
R6621 T10413 T10412 oprd rods,become
R6626 T10414 T10373 punct .,conclude
R6629 T10416 T10417 det This,conclusion
R6634 T10417 T10418 nsubj conclusion,raises
R6637 T10419 T10420 det this,question
R6644 T10420 T10418 dobj question,raises
R6647 T10421 T10420 punct : ,question
R6651 T10422 T10423 advmod Why,lead
R6654 T10423 T10420 acl lead,question
R6658 T10424 T10423 aux does,lead
R6662 T10425 T10423 nsubj loss,lead
R6666 T10426 T10425 prep of,loss
R6670 T10427 T10428 det a,factor
R6674 T10428 T10426 pobj factor,of
R6677 T10429 T10428 amod single,factor
R6681 T10430 T10428 compound transcription,factor
R6684 T10431 T10425 prep within,loss
R6687 T10432 T10433 compound rod,precursors
R6690 T10433 T10431 pobj precursors,within
R6693 T10434 T10423 prep to,lead
R6697 T10435 T10436 nummod two,fates
R6701 T10436 T10434 pobj fates,to
R6705 T10437 T10436 amod alternative,fates
R6708 T10438 T10436 punct —,fates
R6712 T10439 T10440 det a,type
R6715 T10440 T10436 appos type,fates
R6718 T10441 T10440 compound hybrid,type
R6720 T10442 T10440 compound cell,type

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T8198 44-50 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8199 51-57 UBERON:0000966 denotes retina
T8200 141-148 PR_EXT:000001195 denotes S-opsin
T8201 149-159 GO:0010467 denotes expressing
T8202 160-165 CL:0000573 denotes cones
T8203 190-194 CL:0000604 denotes rods
T8204 207-221 CL:0000210 denotes photoreceptors
T8205 240-245 PR_EXT:000011403 denotes Nr2e3
T8206 249-258 GO:0010467 denotes expressed
T8207 267-271 CL:0000604 denotes rods
T8208 281-291 SO_EXT:0000673 denotes transcript
T8209 319-326 GO:0007067 denotes mitotic
T8210 327-332 CL_GO_EXT:cell denotes cells
T8211 389-394 PR_EXT:000011403 denotes Nr2e3
T8212 400-404 CL_GO_EXT:cell denotes cell
T8213 458-464 PR_EXT:000001195 denotes S-cone
T8214 460-464 CL:0000573 denotes cone
T8215 474-479 CL_GO_EXT:cell denotes cells
T8216 495-509 CL:0000210 denotes photoreceptors
T8217 532-538 UBERON:0000966 denotes retina
T8218 546-554 GO_EXT:biological_direction_or_guidance denotes directed
T8219 579-586 GO:0007067 denotes mitotic
T8220 587-592 CL_GO_EXT:cell denotes cells
T8221 622-626 CL:0000604 denotes rods
T8222 692-705 GO_EXT:transcription denotes transcription
T8223 692-712 GO_EXT:transcription_factor denotes transcription factor
T8224 720-723 CL:0000604 denotes rod
T8225 774-778 CL_GO_EXT:cell denotes cell
T8226 824-829 CL:0000573 denotes cones

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7652 51-57 UBERON:0000966 denotes retina
T7653 141-148 PR:000001195 denotes S-opsin
T7654 149-159 GO:0010467 denotes expressing
T7655 160-165 CL:0000573 denotes cones
T7656 190-194 CL:0000604 denotes rods
T7657 207-221 CL:0000210 denotes photoreceptors
T7658 240-245 PR:000011403 denotes Nr2e3
T7659 249-258 GO:0010467 denotes expressed
T7660 267-271 CL:0000604 denotes rods
T7661 281-291 SO:0000673 denotes transcript
T7662 319-326 GO:0007067 denotes mitotic
T7663 389-394 PR:000011403 denotes Nr2e3
T7664 458-464 PR:000001195 denotes S-cone
T7665 460-464 CL:0000573 denotes cone
T7666 495-509 CL:0000210 denotes photoreceptors
T7667 532-538 UBERON:0000966 denotes retina
T7668 579-586 GO:0007067 denotes mitotic
T7669 622-626 CL:0000604 denotes rods
T7670 720-723 CL:0000604 denotes rod
T7671 824-829 CL:0000573 denotes cones