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PMC:1186732 / 34734-35587 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T8584 0-3 DT denotes The
T8585 11-15 NN denotes line
T8586 4-10 JJ denotes second
T8587 28-35 VBZ denotes derives
T8588 16-18 IN denotes of
T8589 19-27 NN denotes evidence
T8590 36-40 IN denotes from
T8591 41-42 DT denotes a
T8592 43-53 NN denotes comparison
T8593 54-56 IN denotes of
T8594 57-60 DT denotes the
T8595 72-79 NN denotes pattern
T8596 61-71 NN denotes expression
T8597 80-82 IN denotes of
T8598 83-87 JJ denotes many
T8599 95-100 NNS denotes genes
T8600 88-92 NN denotes type
T8601 93-94 CD denotes I
T8602 101-103 IN denotes in
T8603 104-107 NN denotes rd7
T8604 120-126 NN denotes mutant
T8605 108-111 CC denotes and
T8606 112-115 NN denotes Nrl
T8607 116-117 SYM denotes −
T8608 117-118 HYPH denotes /
T8609 118-119 SYM denotes −
T8610 127-138 NNS denotes backgrounds
T8611 138-139 . denotes .
T8612 139-292 sentence denotes As mentioned above, Nrl is a retinal transcription factor that, when mutated, results in en masse conversion of rods into S-opsin–expressing cones [24].
T8613 140-142 IN denotes As
T8614 143-152 VBN denotes mentioned
T8615 164-166 VBZ denotes is
T8616 153-158 RB denotes above
T8617 158-160 , denotes ,
T8618 160-163 NN denotes Nrl
T8619 167-168 DT denotes a
T8620 191-197 NN denotes factor
T8621 169-176 JJ denotes retinal
T8622 177-190 NN denotes transcription
T8623 198-202 WDT denotes that
T8624 218-225 VBZ denotes results
T8625 202-204 , denotes ,
T8626 204-208 WRB denotes when
T8627 209-216 VBN denotes mutated
T8628 216-218 , denotes ,
T8629 226-228 IN denotes in
T8630 229-231 FW denotes en
T8631 232-237 FW denotes masse
T8632 238-248 NN denotes conversion
T8633 249-251 IN denotes of
T8634 252-256 NNS denotes rods
T8635 257-261 IN denotes into
T8636 262-263 NN denotes S
T8637 264-269 NN denotes opsin
T8638 263-264 HYPH denotes -
T8639 270-280 VBG denotes expressing
T8640 269-270 HYPH denotes –
T8685 475-482 JJ denotes uniform
T8686 496-498 IN denotes of
T8687 499-503 JJ denotes many
T8688 518-523 NNS denotes genes
T8689 504-508 NN denotes cone
T8690 509-517 JJ denotes specific
T8691 508-509 HYPH denotes -
T8692 524-534 IN denotes throughout
T8693 535-538 DT denotes the
T8694 539-542 NN denotes ONL
T8695 543-547 IN denotes than
T8696 551-555 VBN denotes seen
T8714 628-630 , denotes ,
T8715 630-632 IN denotes in
T8716 633-641 NN denotes addition
T8717 642-644 IN denotes to
T8718 645-648 PRP$ denotes its
T8719 649-659 NN denotes repression
T8720 660-662 IN denotes of
T8721 663-667 NN denotes cone
T8722 668-672 NN denotes gene
T8723 673-683 NN denotes expression
T8724 684-687 IN denotes via
T8725 688-697 NN denotes induction
T8726 698-700 IN denotes of
T8727 701-706 NN denotes Nr2e3
T8728 707-717 NN denotes expression
T8729 717-719 , denotes ,
T8730 719-722 NN denotes Nrl
T8731 730-732 DT denotes an
T8732 744-749 NN denotes level
T8733 733-743 JJ denotes additional
T8749 822-825 RB denotes yet
T8750 826-841 JJ denotes uncharacterized
T8751 841-843 , denotes ,
T8752 852-853 . denotes .
T8641 281-286 NNS denotes cones
T8642 287-288 -LRB- denotes [
T8643 288-290 CD denotes 24
T8644 290-291 -RRB- denotes ]
T8645 291-292 . denotes .
T8646 292-415 sentence denotes It can be inferred from this fact that Nrl is absolutely required for the normal silencing of cone-specific genes in rods.
T8647 293-295 PRP denotes It
T8648 303-311 VBN denotes inferred
T8649 296-299 MD denotes can
T8650 300-302 VB denotes be
T8651 312-316 IN denotes from
T8652 317-321 DT denotes this
T8653 322-326 NN denotes fact
T8654 327-331 IN denotes that
T8655 350-358 VBN denotes required
T8656 332-335 NN denotes Nrl
T8657 336-338 VBZ denotes is
T8658 339-349 RB denotes absolutely
T8659 359-362 IN denotes for
T8660 363-366 DT denotes the
T8661 374-383 NN denotes silencing
T8662 367-373 JJ denotes normal
T8663 384-386 IN denotes of
T8664 387-391 NN denotes cone
T8665 392-400 JJ denotes specific
T8666 391-392 HYPH denotes -
T8667 401-406 NNS denotes genes
T8668 407-409 IN denotes in
T8669 410-414 NNS denotes rods
T8670 414-415 . denotes .
T8671 415-593 sentence denotes In the Nrl homozygous mutant, there is a stronger and more uniform derepression of many cone-specific genes throughout the ONL than is seen in the rd7 retina (unpublished data).
T8672 416-418 IN denotes In
T8673 452-454 VBZ denotes is
T8674 419-422 DT denotes the
T8675 438-444 NN denotes mutant
T8676 423-426 NN denotes Nrl
T8677 427-437 JJ denotes homozygous
T8678 444-446 , denotes ,
T8679 446-451 EX denotes there
T8680 455-456 DT denotes a
T8681 483-495 NN denotes derepression
T8682 457-465 JJR denotes stronger
T8683 466-469 CC denotes and
T8684 470-474 RBR denotes more
T8697 548-550 VBZ denotes is
T8698 556-558 IN denotes in
T8699 559-562 DT denotes the
T8700 567-573 NN denotes retina
T8701 563-566 NN denotes rd7
T8702 574-575 -LRB- denotes (
T8703 587-591 NNS denotes data
T8704 575-586 JJ denotes unpublished
T8705 591-592 -RRB- denotes )
T8706 592-593 . denotes .
T8707 593-853 sentence denotes This finding further suggests that, in addition to its repression of cone gene expression via induction of Nr2e3 expression, Nrl exerts an additional level of negative control over cone genes either directly or via a second, as yet uncharacterized, repressor.
T8708 594-598 DT denotes This
T8709 599-606 NN denotes finding
T8710 615-623 VBZ denotes suggests
T8711 607-614 RB denotes further
T8712 624-628 IN denotes that
T8713 723-729 VBZ denotes exerts
T8734 750-752 IN denotes of
T8735 753-761 JJ denotes negative
T8736 762-769 NN denotes control
T8737 770-774 IN denotes over
T8738 775-779 NN denotes cone
T8739 780-785 NNS denotes genes
T8740 786-792 CC denotes either
T8741 805-808 IN denotes via
T8742 793-801 RB denotes directly
T8743 802-804 CC denotes or
T8744 809-810 DT denotes a
T8745 843-852 NN denotes repressor
T8746 811-817 JJ denotes second
T8747 817-819 , denotes ,
T8748 819-821 RB denotes as
R4783 T8584 T8585 det The,line
R4784 T8585 T8587 nsubj line,derives
R4785 T8586 T8585 amod second,line
R4786 T8588 T8585 prep of,line
R4787 T8589 T8588 pobj evidence,of
R4788 T8590 T8587 prep from,derives
R4789 T8591 T8592 det a,comparison
R4790 T8592 T8590 pobj comparison,from
R4791 T8593 T8592 prep of,comparison
R4792 T8594 T8595 det the,pattern
R4793 T8595 T8593 pobj pattern,of
R4794 T8596 T8595 compound expression,pattern
R4795 T8597 T8595 prep of,pattern
R4796 T8598 T8599 amod many,genes
R4797 T8599 T8597 pobj genes,of
R4798 T8600 T8599 nmod type,genes
R4799 T8601 T8600 nummod I,type
R4800 T8602 T8595 prep in,pattern
R4801 T8603 T8604 nmod rd7,mutant
R4802 T8604 T8610 compound mutant,backgrounds
R4803 T8605 T8603 cc and,rd7
R4804 T8606 T8603 conj Nrl,rd7
R4805 T8607 T8606 punct −,Nrl
R4806 T8608 T8606 punct /,Nrl
R4807 T8609 T8606 punct −,Nrl
R4808 T8610 T8602 pobj backgrounds,in
R4809 T8611 T8587 punct .,derives
R4810 T8613 T8614 mark As,mentioned
R4811 T8614 T8615 advcl mentioned,is
R4812 T8616 T8614 advmod above,mentioned
R4813 T8617 T8615 punct ", ",is
R4814 T8618 T8615 nsubj Nrl,is
R4815 T8619 T8620 det a,factor
R4816 T8620 T8615 attr factor,is
R4817 T8621 T8620 amod retinal,factor
R4818 T8622 T8620 compound transcription,factor
R4819 T8623 T8624 dep that,results
R4820 T8624 T8620 relcl results,factor
R4821 T8625 T8624 punct ", ",results
R4822 T8626 T8627 advmod when,mutated
R4823 T8627 T8624 advcl mutated,results
R4824 T8628 T8624 punct ", ",results
R4825 T8629 T8624 prep in,results
R4826 T8630 T8631 advmod en,masse
R4827 T8631 T8632 amod masse,conversion
R4828 T8632 T8629 pobj conversion,in
R4829 T8633 T8632 prep of,conversion
R4830 T8634 T8633 pobj rods,of
R4831 T8635 T8632 prep into,conversion
R4832 T8636 T8637 compound S,opsin
R4833 T8637 T8639 npadvmod opsin,expressing
R4834 T8638 T8637 punct -,opsin
R4835 T8639 T8641 amod expressing,cones
R4836 T8640 T8639 punct –,expressing
R4837 T8641 T8635 pobj cones,into
R4838 T8642 T8643 punct [,24
R4839 T8643 T8615 parataxis 24,is
R4840 T8644 T8643 punct ],24
R4841 T8645 T8615 punct .,is
R4842 T8647 T8648 nsubjpass It,inferred
R4843 T8649 T8648 aux can,inferred
R4844 T8650 T8648 auxpass be,inferred
R4845 T8651 T8648 prep from,inferred
R4846 T8652 T8653 det this,fact
R4847 T8653 T8651 pobj fact,from
R4848 T8654 T8655 mark that,required
R4849 T8655 T8648 ccomp required,inferred
R4850 T8656 T8655 nsubjpass Nrl,required
R4851 T8657 T8655 auxpass is,required
R4852 T8658 T8655 advmod absolutely,required
R4853 T8659 T8655 prep for,required
R4854 T8660 T8661 det the,silencing
R4855 T8661 T8659 pobj silencing,for
R4856 T8662 T8661 amod normal,silencing
R4857 T8663 T8661 prep of,silencing
R4858 T8664 T8665 npadvmod cone,specific
R4859 T8665 T8667 amod specific,genes
R4860 T8666 T8665 punct -,specific
R4861 T8667 T8663 pobj genes,of
R4862 T8668 T8655 prep in,required
R4863 T8669 T8668 pobj rods,in
R4864 T8670 T8648 punct .,inferred
R4865 T8672 T8673 prep In,is
R4866 T8674 T8675 det the,mutant
R4867 T8675 T8672 pobj mutant,In
R4868 T8676 T8677 npadvmod Nrl,homozygous
R4869 T8677 T8675 amod homozygous,mutant
R4870 T8678 T8673 punct ", ",is
R4871 T8679 T8673 expl there,is
R4872 T8680 T8681 det a,derepression
R4873 T8681 T8673 attr derepression,is
R4874 T8682 T8681 amod stronger,derepression
R4875 T8683 T8682 cc and,stronger
R4876 T8684 T8685 advmod more,uniform
R4877 T8685 T8682 conj uniform,stronger
R4878 T8686 T8681 prep of,derepression
R4879 T8687 T8688 amod many,genes
R4880 T8688 T8686 pobj genes,of
R4881 T8689 T8690 npadvmod cone,specific
R4882 T8690 T8688 amod specific,genes
R4883 T8691 T8690 punct -,specific
R4884 T8692 T8688 prep throughout,genes
R4885 T8693 T8694 det the,ONL
R4886 T8694 T8692 pobj ONL,throughout
R4887 T8695 T8696 mark than,seen
R4888 T8696 T8681 advcl seen,derepression
R4889 T8697 T8696 auxpass is,seen
R4890 T8698 T8696 prep in,seen
R4891 T8699 T8700 det the,retina
R4892 T8700 T8698 pobj retina,in
R4893 T8701 T8700 compound rd7,retina
R4894 T8702 T8703 punct (,data
R4895 T8703 T8673 meta data,is
R4896 T8704 T8703 amod unpublished,data
R4897 T8705 T8703 punct ),data
R4898 T8706 T8673 punct .,is
R4899 T8708 T8709 det This,finding
R4900 T8709 T8710 nsubj finding,suggests
R4901 T8711 T8710 advmod further,suggests
R4902 T8712 T8713 mark that,exerts
R4903 T8713 T8710 ccomp exerts,suggests
R4904 T8714 T8713 punct ", ",exerts
R4905 T8715 T8713 prep in,exerts
R4906 T8716 T8715 pobj addition,in
R4907 T8717 T8716 prep to,addition
R4908 T8718 T8719 poss its,repression
R4909 T8719 T8717 pobj repression,to
R4910 T8720 T8719 prep of,repression
R4911 T8721 T8722 compound cone,gene
R4912 T8722 T8723 compound gene,expression
R4913 T8723 T8720 pobj expression,of
R4914 T8724 T8719 prep via,repression
R4915 T8725 T8724 pobj induction,via
R4916 T8726 T8725 prep of,induction
R4917 T8727 T8728 compound Nr2e3,expression
R4918 T8728 T8726 pobj expression,of
R4919 T8729 T8713 punct ", ",exerts
R4920 T8730 T8713 nsubj Nrl,exerts
R4921 T8731 T8732 det an,level
R4922 T8732 T8713 dobj level,exerts
R4923 T8733 T8732 amod additional,level
R4924 T8734 T8732 prep of,level
R4925 T8735 T8736 amod negative,control
R4926 T8736 T8734 pobj control,of
R4927 T8737 T8736 prep over,control
R4928 T8738 T8739 compound cone,genes
R4929 T8739 T8737 pobj genes,over
R4930 T8740 T8741 preconj either,via
R4931 T8741 T8713 prep via,exerts
R4932 T8742 T8741 advmod directly,via
R4933 T8743 T8741 cc or,via
R4934 T8744 T8745 det a,repressor
R4935 T8745 T8741 pobj repressor,via
R4936 T8746 T8745 amod second,repressor
R4937 T8747 T8745 punct ", ",repressor
R4938 T8748 T8749 advmod as,yet
R4939 T8749 T8750 advmod yet,uncharacterized
R4940 T8750 T8745 amod uncharacterized,repressor
R4941 T8751 T8745 punct ", ",repressor
R4942 T8752 T8710 punct .,suggests

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7891 61-71 GO:0010467 denotes expression
T7892 95-100 SO_EXT:0000704 denotes genes
T7893 112-115 PR_EXT:000011432 denotes Nrl
T7894 116-117 SO_EXT:sequence_nullness_or_absence denotes −
T7895 118-119 SO_EXT:sequence_nullness_or_absence denotes −
T7896 120-126 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T7897 160-163 PR_EXT:000011432 denotes Nrl
T7898 169-176 UBERON:0000966 denotes retinal
T7899 177-190 GO_EXT:transcription denotes transcription
T7900 177-197 GO_EXT:transcription_factor denotes transcription factor
T7901 209-216 SO_EXT:sequence_alteration_process denotes mutated
T7902 252-256 CL:0000604 denotes rods
T7903 262-269 PR_EXT:000001195 denotes S-opsin
T7904 270-280 GO:0010467 denotes expressing
T7905 281-286 CL:0000573 denotes cones
T7906 332-335 PR_EXT:000011432 denotes Nrl
T7907 374-386 _FRAGMENT denotes silencing of
T7908 401-406 GO:0016458 denotes genes
T7909 387-391 CL:0000573 denotes cone
T7910 401-406 SO_EXT:0000704 denotes genes
T7911 410-414 CL:0000604 denotes rods
T7912 423-426 PR_EXT:000011432 denotes Nrl
T7913 438-444 SO_EXT:sequence_altered_entity denotes mutant
T7914 504-508 CL:0000573 denotes cone
T7915 518-523 SO_EXT:0000704 denotes genes
T7916 539-542 UBERON:0001789 denotes ONL
T7917 567-573 UBERON:0000966 denotes retina
T7918 663-667 CL:0000573 denotes cone
T7919 668-672 SO_EXT:0000704 denotes gene
T7920 668-683 GO:0010467 denotes gene expression
T7921 701-706 PR_EXT:000011403 denotes Nr2e3
T7922 707-717 GO:0010467 denotes expression
T7923 719-722 PR_EXT:000011432 denotes Nrl
T7924 753-769 GO_EXT:negative_regulation denotes negative control
T7925 775-779 CL:0000573 denotes cone
T7926 780-785 SO_EXT:0000704 denotes genes
R4598 T7908 T7907 _lexicallyChainedTo genes,silencing of

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7415 61-71 GO:0010467 denotes expression
T7416 95-100 SO:0000704 denotes genes
T7417 112-115 PR:000011432 denotes Nrl
T7418 160-163 PR:000011432 denotes Nrl
T7419 169-176 UBERON:0000966 denotes retinal
T7420 252-256 CL:0000604 denotes rods
T7421 262-269 PR:000001195 denotes S-opsin
T7422 270-280 GO:0010467 denotes expressing
T7423 281-286 CL:0000573 denotes cones
T7424 332-335 PR:000011432 denotes Nrl
T7425 374-386 _FRAGMENT denotes silencing of
T7426 401-406 GO:0016458 denotes genes
T7427 387-391 CL:0000573 denotes cone
T7428 401-406 SO:0000704 denotes genes
T7429 410-414 CL:0000604 denotes rods
T7430 423-426 PR:000011432 denotes Nrl
T7431 504-508 CL:0000573 denotes cone
T7432 518-523 SO:0000704 denotes genes
T7433 539-542 UBERON:0001789 denotes ONL
T7434 567-573 UBERON:0000966 denotes retina
T7435 663-667 CL:0000573 denotes cone
T7436 668-672 SO:0000704 denotes gene
T7437 668-683 GO:0010467 denotes gene expression
T7438 701-706 PR:000011403 denotes Nr2e3
T7439 707-717 GO:0010467 denotes expression
T7440 719-722 PR:000011432 denotes Nrl
T7441 775-779 CL:0000573 denotes cone
T7442 780-785 SO:0000704 denotes genes
R4562 T7426 T7425 _lexicallyChainedTo genes,silencing of

2_test

Id Subject Object Predicate Lexical cue
16110338-11694879-85798530 288-290 11694879 denotes 24
T18690 288-290 11694879 denotes 24