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Id Subject Object Predicate Lexical cue
T705 13-21 VBN denotes Enhanced
T706 29-37 NN denotes syndrome
T707 22-23 NN denotes S
T708 24-28 NN denotes cone
T709 23-24 HYPH denotes -
T710 45-47 VBZ denotes is
T711 38-39 -LRB- denotes (
T712 39-43 NN denotes ESCS
T713 43-44 -RRB- denotes )
T714 48-50 DT denotes an
T715 59-66 NN denotes disease
T716 51-58 JJ denotes unusual
T717 67-69 IN denotes of
T718 70-84 NNS denotes photoreceptors
T719 85-89 WDT denotes that
T720 90-98 VBZ denotes includes
T721 99-104 NN denotes night
T722 105-114 NN denotes blindness
T723 115-116 -LRB- denotes (
T724 116-126 JJ denotes suggestive
T725 127-129 IN denotes of
T726 130-133 NN denotes rod
T727 134-145 NN denotes dysfunction
T728 145-146 -RRB- denotes )
T729 146-148 , denotes ,
T730 148-150 DT denotes an
T731 160-177 NN denotes electroretinogram
T732 151-159 JJ denotes abnormal
T733 178-179 -LRB- denotes (
T734 179-182 NN denotes ERG
T735 182-183 -RRB- denotes )
T736 184-188 IN denotes with
T737 189-190 DT denotes a
T738 191-199 NN denotes waveform
T739 200-204 WDT denotes that
T740 205-207 VBZ denotes is
T741 208-214 RB denotes nearly
T742 215-224 JJ denotes identical
T743 225-230 IN denotes under
T744 231-235 CC denotes both
T745 236-241 NN denotes light
T746 251-261 NN denotes adaptation
T747 242-245 CC denotes and
T748 246-250 NN denotes dark
T749 261-263 , denotes ,
T750 263-266 CC denotes and
T751 267-269 DT denotes an
T752 280-291 NN denotes sensitivity
T753 270-279 VBN denotes increased
T754 292-294 IN denotes of
T755 295-298 DT denotes the
T756 299-302 NN denotes ERG
T757 303-305 IN denotes to
T758 306-311 JJ denotes short
T759 312-322 NN denotes wavelength
T760 311-312 HYPH denotes -
T761 323-328 NN denotes light
T762 329-330 -LRB- denotes [
T763 332-333 CD denotes 2
T764 330-331 CD denotes 1
T765 331-332 , denotes ,
T766 333-334 -RRB- denotes ]
T767 334-335 . denotes .
T768 335-522 sentence denotes The disease is caused by mutations in the orphan nuclear receptor transcription factor NR2E3 (also known as photoreceptor nuclear receptor), which is expressed exclusively in rods [3,4].
T769 336-339 DT denotes The
T770 340-347 NN denotes disease
T771 351-357 VBN denotes caused
T772 348-350 VBZ denotes is
T773 358-360 IN denotes by
T774 361-370 NNS denotes mutations
T775 371-373 IN denotes in
T776 374-377 DT denotes the
T777 416-422 NN denotes factor
T778 378-384 NN denotes orphan
T779 393-401 NN denotes receptor
T780 385-392 JJ denotes nuclear
T781 402-415 NN denotes transcription
T782 423-428 NN denotes NR2E3
T783 429-430 -LRB- denotes (
T784 430-434 RB denotes also
T785 435-440 VBN denotes known
T786 441-443 IN denotes as
T787 444-457 NN denotes photoreceptor
T788 466-474 NN denotes receptor
T789 458-465 JJ denotes nuclear
T790 474-475 -RRB- denotes )
T791 475-477 , denotes ,
T792 477-482 WDT denotes which
T793 486-495 VBN denotes expressed
T794 483-485 VBZ denotes is
T795 496-507 RB denotes exclusively
T796 508-510 IN denotes in
T797 511-515 NNS denotes rods
T798 516-517 -LRB- denotes [
T799 519-520 CD denotes 4
T800 517-518 CD denotes 3
T801 518-519 , denotes ,
T802 520-521 -RRB- denotes ]
T803 521-522 . denotes .
T804 522-687 sentence denotes Recent human genetic studies have also demonstrated mutations in this gene in Goldmann-Favre syndrome and many cases of clumped pigmentary retinal degeneration [5].
T805 523-529 JJ denotes Recent
T806 544-551 NNS denotes studies
T807 530-535 JJ denotes human
T808 536-543 JJ denotes genetic
T809 562-574 VBN denotes demonstrated
T810 552-556 VBP denotes have
T811 557-561 RB denotes also
T812 575-584 NNS denotes mutations
T813 585-587 IN denotes in
T814 588-592 DT denotes this
T815 593-597 NN denotes gene
T816 598-600 IN denotes in
T817 601-609 NNP denotes Goldmann
T818 610-615 NNP denotes Favre
T819 609-610 HYPH denotes -
T820 616-624 NN denotes syndrome
T821 625-628 CC denotes and
T822 629-633 JJ denotes many
T823 634-639 NNS denotes cases
T824 640-642 IN denotes of
T825 643-650 VBN denotes clumped
T826 670-682 NN denotes degeneration
T827 651-661 JJ denotes pigmentary
T828 662-669 JJ denotes retinal
T829 683-684 -LRB- denotes [
T830 684-685 CD denotes 5
T831 685-686 -RRB- denotes ]
T832 686-687 . denotes .
T833 687-865 sentence denotes The initial reports of patients with ESCS attributed the unusual ERG to an abnormally functioning rod photoreceptor system with persistent activity under light adaptation [6–8].
T834 688-691 DT denotes The
T835 700-707 NNS denotes reports
T836 692-699 JJ denotes initial
T837 730-740 VBD denotes attributed
T838 708-710 IN denotes of
T839 711-719 NNS denotes patients
T840 720-724 IN denotes with
T841 725-729 NN denotes ESCS
T842 741-744 DT denotes the
T843 753-756 NN denotes ERG
T844 745-752 JJ denotes unusual
T845 757-759 IN denotes to
T846 760-762 DT denotes an
T847 804-810 NN denotes system
T848 763-773 RB denotes abnormally
T849 774-785 VBG denotes functioning
T850 786-789 NN denotes rod
T851 790-803 NN denotes photoreceptor
T852 811-815 IN denotes with
T853 816-826 JJ denotes persistent
T854 827-835 NN denotes activity
T855 836-841 IN denotes under
T856 842-847 NN denotes light
T857 848-858 NN denotes adaptation
T858 859-860 -LRB- denotes [
T859 860-861 CD denotes 6
T860 861-862 SYM denotes –
T861 862-863 CD denotes 8
T862 863-864 -RRB- denotes ]
T863 864-865 . denotes .
T864 865-1028 sentence denotes Subsequent studies, however, concluded that the ERG was due to supernumerary short-wavelength (“blue”) cone photoreceptors (S-cones) in these patients [1,2,9–11].
T865 866-876 JJ denotes Subsequent
T866 877-884 NNS denotes studies
T867 895-904 VBD denotes concluded
T868 884-886 , denotes ,
T869 886-893 RB denotes however
T870 893-895 , denotes ,
T871 905-909 IN denotes that
T872 918-921 VBD denotes was
T873 910-913 DT denotes the
T874 914-917 NN denotes ERG
T875 922-925 IN denotes due
T876 926-928 IN denotes to
T877 929-942 JJ denotes supernumerary
T878 974-988 NNS denotes photoreceptors
T879 943-948 JJ denotes short
T880 949-959 NN denotes wavelength
T881 948-949 HYPH denotes -
T882 960-961 -LRB- denotes (
T883 962-966 JJ denotes blue
T884 961-962 `` denotes “
T885 966-967 '' denotes ”
T886 967-968 -RRB- denotes )
T887 969-973 NN denotes cone
T888 989-990 -LRB- denotes (
T889 990-991 NN denotes S
T890 992-997 NNS denotes cones
T891 991-992 HYPH denotes -
T892 997-998 -RRB- denotes )
T893 999-1001 IN denotes in
T894 1002-1007 DT denotes these
T895 1008-1016 NNS denotes patients
T896 1017-1018 -LRB- denotes [
T897 1018-1019 CD denotes 1
T898 1019-1020 , denotes ,
T899 1020-1021 CD denotes 2
T900 1021-1022 , denotes ,
T901 1022-1023 CD denotes 9
T902 1023-1024 SYM denotes –
T903 1024-1026 CD denotes 11
T904 1026-1027 -RRB- denotes ]
T905 1027-1028 . denotes .
T906 1028-1247 sentence denotes Histopathologic analysis of a retina from a human patient with ESCS and extensive retinal degeneration demonstrated an absence of rhodopsin-positive cells and an increase in the number of S-cone opsin-expressing cells.
T907 1029-1044 JJ denotes Histopathologic
T908 1045-1053 NN denotes analysis
T909 1132-1144 VBD denotes demonstrated
T910 1054-1056 IN denotes of
T911 1057-1058 DT denotes a
T912 1059-1065 NN denotes retina
T913 1066-1070 IN denotes from
T914 1071-1072 DT denotes a
T915 1079-1086 NN denotes patient
T916 1073-1078 JJ denotes human
T917 1087-1091 IN denotes with
T918 1092-1096 NN denotes ESCS
T919 1097-1100 CC denotes and
T920 1101-1110 JJ denotes extensive
T921 1119-1131 NN denotes degeneration
T922 1111-1118 JJ denotes retinal
T923 1145-1147 DT denotes an
T924 1148-1155 NN denotes absence
T925 1156-1158 IN denotes of
T926 1159-1168 NN denotes rhodopsin
T927 1169-1177 JJ denotes positive
T928 1168-1169 HYPH denotes -
T929 1178-1183 NNS denotes cells
T930 1184-1187 CC denotes and
T931 1188-1190 DT denotes an
T932 1191-1199 NN denotes increase
T933 1200-1202 IN denotes in
T934 1203-1206 DT denotes the
T935 1207-1213 NN denotes number
T936 1214-1216 IN denotes of
T937 1217-1218 NN denotes S
T938 1219-1223 NN denotes cone
T939 1218-1219 HYPH denotes -
T940 1241-1246 NNS denotes cells
T941 1224-1229 NN denotes opsin
T942 1230-1240 VBG denotes expressing
T943 1229-1230 HYPH denotes -
T944 1246-1247 . denotes .
T945 1247-1483 sentence denotes Nevertheless, the overall density of cones was only modestly increased in this patient (approximately 2-fold), suggesting that there might be additional factors that contribute to the very large, light-adapted ERG seen in this disease.
T946 1248-1260 RB denotes Nevertheless
T947 1309-1318 VBN denotes increased
T948 1260-1262 , denotes ,
T949 1262-1265 DT denotes the
T950 1274-1281 NN denotes density
T951 1266-1273 JJ denotes overall
T952 1282-1284 IN denotes of
T953 1285-1290 NNS denotes cones
T954 1291-1294 VBD denotes was
T955 1295-1299 RB denotes only
T956 1300-1308 RB denotes modestly
T957 1319-1321 IN denotes in
T958 1322-1326 DT denotes this
T959 1327-1334 NN denotes patient
T960 1335-1336 -LRB- denotes (
T961 1352-1356 RB denotes fold
T962 1336-1349 RB denotes approximately
T963 1350-1351 CD denotes 2
T964 1351-1352 HYPH denotes -
T965 1356-1357 -RRB- denotes )
T966 1357-1359 , denotes ,
T967 1359-1369 VBG denotes suggesting
T968 1370-1374 IN denotes that
T969 1387-1389 VB denotes be
T970 1375-1380 EX denotes there
T971 1381-1386 MD denotes might
T972 1390-1400 JJ denotes additional
T973 1401-1408 NNS denotes factors
T974 1409-1413 WDT denotes that
T975 1414-1424 VBP denotes contribute
T976 1425-1427 IN denotes to
T977 1428-1431 DT denotes the
T978 1458-1461 NN denotes ERG
T979 1432-1436 RB denotes very
T980 1437-1442 JJ denotes large
T981 1442-1444 , denotes ,
T982 1444-1449 NN denotes light
T983 1450-1457 VBN denotes adapted
T984 1449-1450 HYPH denotes -
T985 1462-1466 VBN denotes seen
T986 1467-1469 IN denotes in
T987 1470-1474 DT denotes this
T988 1475-1482 NN denotes disease
T989 1482-1483 . denotes .
T990 1483-1743 sentence denotes In addition to the ERG findings, patients with ESCS have dysmorphic retinas with rosette formation in the outer nuclear layer (ONL) where photoreceptor cell bodies reside, and a slow retinal degeneration that can ultimately lead to complete blindness [12–14].
T991 1484-1486 IN denotes In
T992 1536-1540 VBP denotes have
T993 1487-1495 NN denotes addition
T994 1496-1498 IN denotes to
T995 1499-1502 DT denotes the
T996 1507-1515 NNS denotes findings
T997 1503-1506 NN denotes ERG
T998 1515-1517 , denotes ,
T999 1517-1525 NNS denotes patients
T1000 1526-1530 IN denotes with
T1001 1531-1535 NN denotes ESCS
T1002 1541-1551 JJ denotes dysmorphic
T1003 1552-1559 NNS denotes retinas
T1004 1560-1564 IN denotes with
T1005 1565-1572 NN denotes rosette
T1006 1573-1582 NN denotes formation
T1007 1583-1585 IN denotes in
T1008 1586-1589 DT denotes the
T1009 1604-1609 NN denotes layer
T1010 1590-1595 JJ denotes outer
T1011 1596-1603 JJ denotes nuclear
T1012 1610-1611 -LRB- denotes (
T1013 1611-1614 NN denotes ONL
T1014 1614-1615 -RRB- denotes )
T1015 1616-1621 WRB denotes where
T1016 1648-1654 VBP denotes reside
T1017 1622-1635 NN denotes photoreceptor
T1018 1641-1647 NNS denotes bodies
T1019 1636-1640 NN denotes cell
T1020 1654-1656 , denotes ,
T1021 1656-1659 CC denotes and
T1022 1660-1661 DT denotes a
T1023 1675-1687 NN denotes degeneration
T1024 1662-1666 JJ denotes slow
T1025 1667-1674 JJ denotes retinal
T1026 1688-1692 WDT denotes that
T1027 1708-1712 VB denotes lead
T1028 1693-1696 MD denotes can
T1029 1697-1707 RB denotes ultimately
T1030 1713-1715 IN denotes to
T1031 1716-1724 JJ denotes complete
T1032 1725-1734 NN denotes blindness
T1033 1735-1736 -LRB- denotes [
T1034 1736-1738 CD denotes 12
T1035 1738-1739 SYM denotes –
T1036 1739-1741 CD denotes 14
T1037 1741-1742 -RRB- denotes ]
T1038 1742-1743 . denotes .
T1039 1743-1866 sentence denotes Mutations in the mouse ortholog of NR2E3 have been identified in the spontaneous mutant retinal degeneration 7 (rd7) [15].
T1040 1744-1753 NNS denotes Mutations
T1041 1795-1805 VBN denotes identified
T1042 1754-1756 IN denotes in
T1043 1757-1760 DT denotes the
T1044 1767-1775 NN denotes ortholog
T1045 1761-1766 NN denotes mouse
T1046 1776-1778 IN denotes of
T1047 1779-1784 NN denotes NR2E3
T1048 1785-1789 VBP denotes have
T1049 1790-1794 VBN denotes been
T1050 1806-1808 IN denotes in
T1051 1809-1812 DT denotes the
T1052 1840-1852 NN denotes degeneration
T1053 1813-1824 JJ denotes spontaneous
T1054 1825-1831 NN denotes mutant
T1055 1832-1839 JJ denotes retinal
T1056 1853-1854 CD denotes 7
T1057 1855-1856 -LRB- denotes (
T1058 1856-1859 NN denotes rd7
T1059 1859-1860 -RRB- denotes )
T1060 1861-1862 -LRB- denotes [
T1061 1862-1864 CD denotes 15
T1062 1864-1865 -RRB- denotes ]
T1063 1865-1866 . denotes .
T1064 1866-1984 sentence denotes This mutant demonstrates slow retinal degeneration and abnormal lamination of the ONL with rosette formation [15,16].
T1065 1867-1871 DT denotes This
T1066 1872-1878 NN denotes mutant
T1067 1879-1891 VBZ denotes demonstrates
T1068 1892-1896 JJ denotes slow
T1069 1905-1917 NN denotes degeneration
T1070 1897-1904 JJ denotes retinal
T1071 1918-1921 CC denotes and
T1072 1922-1930 JJ denotes abnormal
T1073 1931-1941 NN denotes lamination
T1074 1942-1944 IN denotes of
T1075 1945-1948 DT denotes the
T1076 1949-1952 NN denotes ONL
T1077 1953-1957 IN denotes with
T1078 1958-1965 NN denotes rosette
T1079 1966-1975 NN denotes formation
T1080 1976-1977 -LRB- denotes [
T1081 1980-1982 CD denotes 16
T1082 1977-1979 CD denotes 15
T1083 1979-1980 , denotes ,
T1084 1982-1983 -RRB- denotes ]
T1085 1983-1984 . denotes .
T1086 1984-2175 sentence denotes Curiously, the ERG of the mouse under both light and dark adaptation has been reported to be normal, showing progressive attenuation with time, presumably due to degenerative cell loss [15].
T1087 1985-1994 RB denotes Curiously
T1088 2063-2071 VBN denotes reported
T1089 1994-1996 , denotes ,
T1090 1996-1999 DT denotes the
T1091 2000-2003 NN denotes ERG
T1092 2004-2006 IN denotes of
T1093 2007-2010 DT denotes the
T1094 2011-2016 NN denotes mouse
T1095 2017-2022 IN denotes under
T1096 2023-2027 CC denotes both
T1097 2028-2033 NN denotes light
T1098 2043-2053 NN denotes adaptation
T1099 2034-2037 CC denotes and
T1100 2038-2042 NN denotes dark
T1101 2054-2057 VBZ denotes has
T1102 2058-2062 VBN denotes been
T1103 2072-2074 TO denotes to
T1104 2075-2077 VB denotes be
T1105 2078-2084 JJ denotes normal
T1106 2084-2086 , denotes ,
T1107 2086-2093 VBG denotes showing
T1108 2094-2105 JJ denotes progressive
T1109 2106-2117 NN denotes attenuation
T1110 2118-2122 IN denotes with
T1111 2123-2127 NN denotes time
T1112 2127-2129 , denotes ,
T1113 2129-2139 RB denotes presumably
T1114 2140-2143 IN denotes due
T1115 2144-2146 IN denotes to
T1116 2147-2159 JJ denotes degenerative
T1117 2165-2169 NN denotes loss
T1118 2160-2164 NN denotes cell
T1119 2170-2171 -LRB- denotes [
T1120 2171-2173 CD denotes 15
T1121 2173-2174 -RRB- denotes ]
T1122 2174-2175 . denotes .
T1123 2175-2303 sentence denotes A prior study showed a 2- to 3-fold increase in the number S-opsin–positive cells in the rd7 retina compared to wild type [17].
T1124 2176-2177 DT denotes A
T1125 2184-2189 NN denotes study
T1126 2178-2183 JJ denotes prior
T1127 2190-2196 VBD denotes showed
T1128 2197-2198 DT denotes a
T1129 2212-2220 NN denotes increase
T1130 2199-2200 CD denotes 2
T1131 2205-2206 CD denotes 3
T1132 2200-2201 HYPH denotes -
T1133 2202-2204 IN denotes to
T1134 2207-2211 JJ denotes fold
T1135 2206-2207 HYPH denotes -
T1136 2221-2223 IN denotes in
T1137 2224-2227 DT denotes the
T1138 2228-2234 NN denotes number
T1139 2235-2236 NN denotes S
T1140 2243-2251 JJ denotes positive
T1141 2236-2237 HYPH denotes -
T1142 2237-2242 NN denotes opsin
T1143 2242-2243 HYPH denotes –
T1144 2252-2257 NNS denotes cells
T1145 2258-2260 IN denotes in
T1146 2261-2264 DT denotes the
T1147 2269-2275 NN denotes retina
T1148 2265-2268 NN denotes rd7
T1149 2276-2284 VBN denotes compared
T1150 2285-2287 IN denotes to
T1151 2288-2292 JJ denotes wild
T1152 2293-2297 NN denotes type
T1153 2298-2299 -LRB- denotes [
T1154 2299-2301 CD denotes 17
T1155 2301-2302 -RRB- denotes ]
T1156 2302-2303 . denotes .
T1157 2303-2410 sentence denotes In addition, two groups recently reported derepression of additional cone genes in the rd7 mutant [18,19].
T1158 2304-2306 IN denotes In
T1159 2337-2345 VBD denotes reported
T1160 2307-2315 NN denotes addition
T1161 2315-2317 , denotes ,
T1162 2317-2320 CD denotes two
T1163 2321-2327 NNS denotes groups
T1164 2328-2336 RB denotes recently
T1165 2346-2358 NN denotes derepression
T1166 2359-2361 IN denotes of
T1167 2362-2372 JJ denotes additional
T1168 2378-2383 NNS denotes genes
T1169 2373-2377 NN denotes cone
T1170 2384-2386 IN denotes in
T1171 2387-2390 DT denotes the
T1172 2395-2401 NN denotes mutant
T1173 2391-2394 NN denotes rd7
T1174 2402-2403 -LRB- denotes [
T1175 2406-2408 CD denotes 19
T1176 2403-2405 CD denotes 18
T1177 2405-2406 , denotes ,
T1178 2408-2409 -RRB- denotes ]
T1179 2409-2410 . denotes .
T1180 2410-2572 sentence denotes In order to better understand the mechanistic basis of ESCS, we undertook a molecular and ultrastructural analysis of the photoreceptors of the rd7 mutant mouse.
T1181 2411-2413 IN denotes In
T1182 2475-2484 VBD denotes undertook
T1183 2414-2419 NN denotes order
T1184 2420-2422 TO denotes to
T1185 2430-2440 VB denotes understand
T1186 2423-2429 RBR denotes better
T1187 2441-2444 DT denotes the
T1188 2457-2462 NN denotes basis
T1189 2445-2456 JJ denotes mechanistic
T1190 2463-2465 IN denotes of
T1191 2466-2470 NN denotes ESCS
T1192 2470-2472 , denotes ,
T1193 2472-2474 PRP denotes we
T1194 2485-2486 DT denotes a
T1195 2517-2525 NN denotes analysis
T1196 2487-2496 JJ denotes molecular
T1197 2497-2500 CC denotes and
T1198 2501-2516 JJ denotes ultrastructural
T1199 2526-2528 IN denotes of
T1200 2529-2532 DT denotes the
T1201 2533-2547 NNS denotes photoreceptors
T1202 2548-2550 IN denotes of
T1203 2551-2554 DT denotes the
T1204 2566-2571 NN denotes mouse
T1205 2555-2558 NN denotes rd7
T1206 2559-2565 NN denotes mutant
T1207 2571-2572 . denotes .
T1208 2572-2773 sentence denotes Microarray and in situ hybridization analyses revealed a modest increase in the number of S-opsin–positive cells and widespread derepression of many cone-specific genes within rod photoreceptor cells.
T1209 2573-2583 NN denotes Microarray
T1210 2610-2618 NNS denotes analyses
T1211 2584-2587 CC denotes and
T1212 2588-2590 FW denotes in
T1213 2591-2595 FW denotes situ
T1214 2596-2609 NN denotes hybridization
T1215 2619-2627 VBD denotes revealed
T1216 2628-2629 DT denotes a
T1217 2637-2645 NN denotes increase
T1218 2630-2636 JJ denotes modest
T1219 2646-2648 IN denotes in
T1220 2649-2652 DT denotes the
T1221 2653-2659 NN denotes number
T1222 2660-2662 IN denotes of
T1223 2663-2664 NN denotes S
T1224 2671-2679 JJ denotes positive
T1225 2664-2665 HYPH denotes -
T1226 2665-2670 JJ denotes opsin
T1227 2670-2671 HYPH denotes –
T1228 2680-2685 NNS denotes cells
T1229 2686-2689 CC denotes and
T1230 2690-2700 JJ denotes widespread
T1231 2701-2713 NN denotes derepression
T1232 2714-2716 IN denotes of
T1233 2717-2721 JJ denotes many
T1234 2736-2741 NNS denotes genes
T1235 2722-2726 NN denotes cone
T1236 2727-2735 JJ denotes specific
T1237 2726-2727 HYPH denotes -
T1238 2742-2748 IN denotes within
T1239 2749-2752 NN denotes rod
T1240 2767-2772 NNS denotes cells
T1241 2753-2766 NN denotes photoreceptor
T1242 2772-2773 . denotes .
T1243 2773-2967 sentence denotes Ultrastructural studies demonstrated that the cells that coexpress rod and cone genes in the rd7 retina represent a morphologically hybrid cell type, intermediate between normal rods and cones.
T1244 2774-2789 JJ denotes Ultrastructural
T1245 2790-2797 NNS denotes studies
T1246 2798-2810 VBD denotes demonstrated
T1247 2811-2815 IN denotes that
T1248 2878-2887 VBP denotes represent
T1249 2816-2819 DT denotes the
T1250 2820-2825 NNS denotes cells
T1251 2826-2830 WDT denotes that
T1252 2831-2840 VBP denotes coexpress
T1253 2841-2844 NN denotes rod
T1254 2854-2859 NNS denotes genes
T1255 2845-2848 CC denotes and
T1256 2849-2853 NN denotes cone
T1257 2860-2862 IN denotes in
T1258 2863-2866 DT denotes the
T1259 2871-2877 NN denotes retina
T1260 2867-2870 NN denotes rd7
T1261 2888-2889 DT denotes a
T1262 2918-2922 NN denotes type
T1263 2890-2905 RB denotes morphologically
T1264 2906-2912 JJ denotes hybrid
T1265 2913-2917 NN denotes cell
T1266 2922-2924 , denotes ,
T1267 2924-2936 JJ denotes intermediate
T1268 2937-2944 IN denotes between
T1269 2945-2951 JJ denotes normal
T1270 2952-2956 NNS denotes rods
T1271 2957-2960 CC denotes and
T1272 2961-2966 NNS denotes cones
T1273 2966-2967 . denotes .
R295 T705 T706 amod Enhanced,syndrome
R296 T706 T710 nsubj syndrome,is
R297 T707 T708 compound S,cone
R298 T708 T706 compound cone,syndrome
R299 T709 T708 punct -,cone
R300 T711 T706 punct (,syndrome
R301 T712 T706 appos ESCS,syndrome
R302 T713 T710 punct ),is
R303 T714 T715 det an,disease
R304 T715 T710 attr disease,is
R305 T716 T715 amod unusual,disease
R306 T717 T715 prep of,disease
R307 T718 T717 pobj photoreceptors,of
R308 T719 T720 dep that,includes
R309 T720 T715 relcl includes,disease
R310 T721 T722 compound night,blindness
R311 T722 T720 dobj blindness,includes
R312 T723 T722 punct (,blindness
R313 T724 T722 amod suggestive,blindness
R314 T725 T724 prep of,suggestive
R315 T726 T727 compound rod,dysfunction
R316 T727 T725 pobj dysfunction,of
R317 T728 T722 punct ),blindness
R318 T729 T722 punct ", ",blindness
R319 T730 T731 det an,electroretinogram
R320 T731 T722 conj electroretinogram,blindness
R321 T732 T731 amod abnormal,electroretinogram
R322 T733 T731 punct (,electroretinogram
R323 T734 T731 appos ERG,electroretinogram
R324 T735 T731 punct ),electroretinogram
R325 T736 T731 prep with,electroretinogram
R326 T737 T738 det a,waveform
R327 T738 T736 pobj waveform,with
R328 T739 T740 dep that,is
R329 T740 T738 relcl is,waveform
R330 T741 T742 advmod nearly,identical
R331 T742 T740 acomp identical,is
R332 T743 T740 prep under,is
R333 T744 T745 preconj both,light
R334 T745 T746 nmod light,adaptation
R335 T746 T743 pobj adaptation,under
R336 T747 T745 cc and,light
R337 T748 T745 conj dark,light
R338 T749 T731 punct ", ",electroretinogram
R339 T750 T731 cc and,electroretinogram
R340 T751 T752 det an,sensitivity
R341 T752 T731 conj sensitivity,electroretinogram
R342 T753 T752 amod increased,sensitivity
R343 T754 T752 prep of,sensitivity
R344 T755 T756 det the,ERG
R345 T756 T754 pobj ERG,of
R346 T757 T752 prep to,sensitivity
R347 T758 T759 amod short,wavelength
R348 T759 T761 compound wavelength,light
R349 T760 T759 punct -,wavelength
R350 T761 T757 pobj light,to
R351 T762 T763 punct [,2
R352 T763 T710 parataxis 2,is
R353 T764 T763 nummod 1,2
R354 T765 T763 punct ",",2
R355 T766 T763 punct ],2
R356 T767 T710 punct .,is
R357 T769 T770 det The,disease
R358 T770 T771 nsubjpass disease,caused
R359 T772 T771 auxpass is,caused
R360 T773 T771 agent by,caused
R361 T774 T773 pobj mutations,by
R362 T775 T774 prep in,mutations
R363 T776 T777 det the,factor
R364 T777 T775 pobj factor,in
R365 T778 T779 nmod orphan,receptor
R366 T779 T777 compound receptor,factor
R367 T780 T779 amod nuclear,receptor
R368 T781 T777 compound transcription,factor
R369 T782 T777 appos NR2E3,factor
R370 T783 T777 punct (,factor
R371 T784 T785 advmod also,known
R372 T785 T777 acl known,factor
R373 T786 T785 prep as,known
R374 T787 T788 nmod photoreceptor,receptor
R375 T788 T786 pobj receptor,as
R376 T789 T788 amod nuclear,receptor
R377 T790 T777 punct ),factor
R378 T791 T777 punct ", ",factor
R379 T792 T793 dep which,expressed
R380 T793 T777 relcl expressed,factor
R381 T794 T793 auxpass is,expressed
R382 T795 T793 advmod exclusively,expressed
R383 T796 T793 prep in,expressed
R384 T797 T796 pobj rods,in
R385 T798 T799 punct [,4
R386 T799 T771 parataxis 4,caused
R387 T800 T799 nummod 3,4
R388 T801 T799 punct ",",4
R389 T802 T799 punct ],4
R390 T803 T771 punct .,caused
R391 T805 T806 amod Recent,studies
R392 T806 T809 nsubj studies,demonstrated
R393 T807 T806 amod human,studies
R394 T808 T806 amod genetic,studies
R395 T810 T809 aux have,demonstrated
R396 T811 T809 advmod also,demonstrated
R397 T812 T809 dobj mutations,demonstrated
R398 T813 T809 prep in,demonstrated
R399 T814 T815 det this,gene
R400 T815 T813 pobj gene,in
R401 T816 T809 prep in,demonstrated
R402 T817 T818 compound Goldmann,Favre
R403 T818 T820 compound Favre,syndrome
R404 T819 T818 punct -,Favre
R405 T820 T816 pobj syndrome,in
R406 T821 T820 cc and,syndrome
R407 T822 T823 amod many,cases
R408 T823 T820 conj cases,syndrome
R409 T824 T823 prep of,cases
R410 T825 T826 amod clumped,degeneration
R411 T826 T824 pobj degeneration,of
R412 T827 T826 amod pigmentary,degeneration
R413 T828 T826 amod retinal,degeneration
R414 T829 T830 punct [,5
R415 T830 T809 parataxis 5,demonstrated
R416 T831 T830 punct ],5
R417 T832 T809 punct .,demonstrated
R418 T834 T835 det The,reports
R419 T835 T837 nsubj reports,attributed
R420 T836 T835 amod initial,reports
R421 T838 T835 prep of,reports
R422 T839 T838 pobj patients,of
R423 T840 T839 prep with,patients
R424 T841 T840 pobj ESCS,with
R425 T842 T843 det the,ERG
R426 T843 T837 dobj ERG,attributed
R427 T844 T843 amod unusual,ERG
R428 T845 T837 prep to,attributed
R429 T846 T847 det an,system
R430 T847 T845 pobj system,to
R431 T848 T849 advmod abnormally,functioning
R432 T849 T847 amod functioning,system
R433 T850 T847 compound rod,system
R434 T851 T847 compound photoreceptor,system
R435 T852 T847 prep with,system
R436 T853 T854 amod persistent,activity
R437 T854 T852 pobj activity,with
R438 T855 T854 prep under,activity
R439 T856 T857 compound light,adaptation
R440 T857 T855 pobj adaptation,under
R441 T858 T859 punct [,6
R442 T859 T837 parataxis 6,attributed
R443 T860 T861 punct –,8
R444 T861 T859 prep 8,6
R445 T862 T859 punct ],6
R446 T863 T837 punct .,attributed
R447 T865 T866 amod Subsequent,studies
R448 T866 T867 nsubj studies,concluded
R449 T868 T867 punct ", ",concluded
R450 T869 T867 advmod however,concluded
R451 T870 T867 punct ", ",concluded
R452 T871 T872 mark that,was
R453 T872 T867 ccomp was,concluded
R454 T873 T874 det the,ERG
R455 T874 T872 nsubj ERG,was
R456 T875 T872 prep due,was
R457 T876 T875 pcomp to,due
R458 T877 T878 amod supernumerary,photoreceptors
R459 T878 T875 pobj photoreceptors,due
R460 T879 T880 amod short,wavelength
R461 T880 T878 nmod wavelength,photoreceptors
R462 T881 T880 punct -,wavelength
R463 T882 T883 punct (,blue
R464 T883 T878 parataxis blue,photoreceptors
R465 T884 T883 punct “,blue
R466 T885 T883 punct ”,blue
R467 T886 T883 punct ),blue
R468 T887 T878 compound cone,photoreceptors
R469 T888 T878 punct (,photoreceptors
R470 T889 T890 compound S,cones
R471 T890 T878 appos cones,photoreceptors
R472 T891 T890 punct -,cones
R473 T892 T878 punct ),photoreceptors
R474 T893 T878 prep in,photoreceptors
R475 T894 T895 det these,patients
R476 T895 T893 pobj patients,in
R477 T896 T897 punct [,1
R478 T897 T872 parataxis 1,was
R479 T898 T897 punct ",",1
R480 T899 T897 appos 2,1
R481 T900 T897 punct ",",1
R482 T901 T897 appos 9,1
R483 T902 T903 punct –,11
R484 T903 T901 prep 11,9
R485 T904 T897 punct ],1
R486 T905 T867 punct .,concluded
R487 T907 T908 amod Histopathologic,analysis
R488 T908 T909 nsubj analysis,demonstrated
R489 T910 T908 prep of,analysis
R490 T911 T912 det a,retina
R491 T912 T910 pobj retina,of
R492 T913 T912 prep from,retina
R493 T914 T915 det a,patient
R494 T915 T913 pobj patient,from
R495 T916 T915 amod human,patient
R496 T917 T915 prep with,patient
R497 T918 T917 pobj ESCS,with
R498 T919 T918 cc and,ESCS
R499 T920 T921 amod extensive,degeneration
R500 T921 T918 conj degeneration,ESCS
R501 T922 T921 amod retinal,degeneration
R502 T923 T924 det an,absence
R503 T924 T909 dobj absence,demonstrated
R504 T925 T924 prep of,absence
R505 T926 T927 npadvmod rhodopsin,positive
R506 T927 T929 amod positive,cells
R507 T928 T927 punct -,positive
R508 T929 T925 pobj cells,of
R509 T930 T924 cc and,absence
R510 T931 T932 det an,increase
R511 T932 T924 conj increase,absence
R512 T933 T932 prep in,increase
R513 T934 T935 det the,number
R514 T935 T933 pobj number,in
R515 T936 T935 prep of,number
R516 T937 T938 nmod S,cone
R517 T938 T940 nmod cone,cells
R518 T939 T938 punct -,cone
R519 T940 T936 pobj cells,of
R520 T941 T942 npadvmod opsin,expressing
R521 T942 T940 amod expressing,cells
R522 T943 T942 punct -,expressing
R523 T944 T909 punct .,demonstrated
R524 T946 T947 advmod Nevertheless,increased
R525 T948 T947 punct ", ",increased
R526 T949 T950 det the,density
R527 T950 T947 nsubjpass density,increased
R528 T951 T950 amod overall,density
R529 T952 T950 prep of,density
R530 T953 T952 pobj cones,of
R531 T954 T947 auxpass was,increased
R532 T955 T956 advmod only,modestly
R533 T956 T947 advmod modestly,increased
R534 T957 T947 prep in,increased
R535 T958 T959 det this,patient
R536 T959 T957 pobj patient,in
R537 T960 T961 punct (,fold
R538 T961 T947 parataxis fold,increased
R539 T962 T963 advmod approximately,2
R540 T963 T961 quantmod 2,fold
R541 T964 T961 punct -,fold
R542 T965 T961 punct ),fold
R543 T966 T947 punct ", ",increased
R544 T967 T947 advcl suggesting,increased
R545 T968 T969 mark that,be
R546 T969 T967 ccomp be,suggesting
R547 T970 T969 expl there,be
R548 T971 T969 aux might,be
R549 T972 T973 amod additional,factors
R550 T973 T969 attr factors,be
R551 T974 T975 dep that,contribute
R552 T975 T973 relcl contribute,factors
R553 T976 T975 prep to,contribute
R554 T977 T978 det the,ERG
R555 T978 T976 pobj ERG,to
R556 T979 T980 advmod very,large
R557 T980 T978 amod large,ERG
R558 T981 T978 punct ", ",ERG
R559 T982 T983 npadvmod light,adapted
R560 T983 T978 amod adapted,ERG
R561 T984 T983 punct -,adapted
R562 T985 T978 acl seen,ERG
R563 T986 T985 prep in,seen
R564 T987 T988 det this,disease
R565 T988 T986 pobj disease,in
R566 T989 T947 punct .,increased
R567 T991 T992 prep In,have
R568 T993 T991 pobj addition,In
R569 T994 T993 prep to,addition
R570 T995 T996 det the,findings
R571 T996 T994 pobj findings,to
R572 T997 T996 compound ERG,findings
R573 T998 T992 punct ", ",have
R574 T999 T992 nsubj patients,have
R575 T1000 T999 prep with,patients
R576 T1001 T1000 pobj ESCS,with
R577 T1002 T1003 amod dysmorphic,retinas
R578 T1003 T992 dobj retinas,have
R579 T1004 T1003 prep with,retinas
R580 T1005 T1006 compound rosette,formation
R581 T1006 T1004 pobj formation,with
R582 T1007 T1006 prep in,formation
R583 T1008 T1009 det the,layer
R584 T1009 T1007 pobj layer,in
R585 T1010 T1009 amod outer,layer
R586 T1011 T1009 amod nuclear,layer
R587 T1012 T1009 punct (,layer
R588 T1013 T1009 appos ONL,layer
R589 T1014 T1009 punct ),layer
R590 T1015 T1016 advmod where,reside
R591 T1016 T1009 relcl reside,layer
R592 T1017 T1018 compound photoreceptor,bodies
R593 T1018 T1016 nsubj bodies,reside
R594 T1019 T1018 compound cell,bodies
R595 T1020 T1003 punct ", ",retinas
R596 T1021 T1003 cc and,retinas
R597 T1022 T1023 det a,degeneration
R598 T1023 T1003 conj degeneration,retinas
R599 T1024 T1023 amod slow,degeneration
R600 T1025 T1023 amod retinal,degeneration
R601 T1026 T1027 dep that,lead
R602 T1027 T1023 relcl lead,degeneration
R603 T1028 T1027 aux can,lead
R604 T1029 T1027 advmod ultimately,lead
R605 T1030 T1027 prep to,lead
R606 T1031 T1032 amod complete,blindness
R607 T1032 T1030 pobj blindness,to
R608 T1033 T1034 punct [,12
R609 T1034 T992 parataxis 12,have
R610 T1035 T1036 punct –,14
R611 T1036 T1034 prep 14,12
R612 T1037 T1034 punct ],12
R613 T1038 T992 punct .,have
R614 T1040 T1041 nsubjpass Mutations,identified
R615 T1042 T1040 prep in,Mutations
R616 T1043 T1044 det the,ortholog
R617 T1044 T1042 pobj ortholog,in
R618 T1045 T1044 compound mouse,ortholog
R619 T1046 T1044 prep of,ortholog
R620 T1047 T1046 pobj NR2E3,of
R621 T1048 T1041 aux have,identified
R622 T1049 T1041 auxpass been,identified
R623 T1050 T1041 prep in,identified
R624 T1051 T1052 det the,degeneration
R625 T1052 T1050 pobj degeneration,in
R626 T1053 T1052 amod spontaneous,degeneration
R627 T1054 T1052 nmod mutant,degeneration
R628 T1055 T1052 amod retinal,degeneration
R629 T1056 T1052 nummod 7,degeneration
R630 T1057 T1052 punct (,degeneration
R631 T1058 T1052 appos rd7,degeneration
R632 T1059 T1041 punct ),identified
R633 T1060 T1061 punct [,15
R634 T1061 T1041 parataxis 15,identified
R635 T1062 T1061 punct ],15
R636 T1063 T1041 punct .,identified
R637 T1065 T1066 det This,mutant
R638 T1066 T1067 nsubj mutant,demonstrates
R639 T1068 T1069 amod slow,degeneration
R640 T1069 T1067 dobj degeneration,demonstrates
R641 T1070 T1069 amod retinal,degeneration
R642 T1071 T1069 cc and,degeneration
R643 T1072 T1073 amod abnormal,lamination
R644 T1073 T1069 conj lamination,degeneration
R645 T1074 T1073 prep of,lamination
R646 T1075 T1076 det the,ONL
R647 T1076 T1074 pobj ONL,of
R648 T1077 T1073 prep with,lamination
R649 T1078 T1079 compound rosette,formation
R650 T1079 T1077 pobj formation,with
R651 T1080 T1081 punct [,16
R652 T1081 T1067 parataxis 16,demonstrates
R653 T1082 T1081 nummod 15,16
R654 T1083 T1081 punct ",",16
R655 T1084 T1081 punct ],16
R656 T1085 T1067 punct .,demonstrates
R657 T1087 T1088 advmod Curiously,reported
R658 T1089 T1088 punct ", ",reported
R659 T1090 T1091 det the,ERG
R660 T1091 T1088 nsubjpass ERG,reported
R661 T1092 T1091 prep of,ERG
R662 T1093 T1094 det the,mouse
R663 T1094 T1092 pobj mouse,of
R664 T1095 T1091 prep under,ERG
R665 T1096 T1097 preconj both,light
R666 T1097 T1098 nmod light,adaptation
R667 T1098 T1095 pobj adaptation,under
R668 T1099 T1097 cc and,light
R669 T1100 T1097 conj dark,light
R670 T1101 T1088 aux has,reported
R671 T1102 T1088 auxpass been,reported
R672 T1103 T1104 aux to,be
R673 T1104 T1088 xcomp be,reported
R674 T1105 T1104 acomp normal,be
R675 T1106 T1088 punct ", ",reported
R676 T1107 T1088 advcl showing,reported
R677 T1108 T1109 amod progressive,attenuation
R678 T1109 T1107 dobj attenuation,showing
R679 T1110 T1107 prep with,showing
R680 T1111 T1110 pobj time,with
R681 T1112 T1107 punct ", ",showing
R682 T1113 T1114 advmod presumably,due
R683 T1114 T1107 prep due,showing
R684 T1115 T1114 pcomp to,due
R685 T1116 T1117 amod degenerative,loss
R686 T1117 T1114 pobj loss,due
R687 T1118 T1117 compound cell,loss
R688 T1119 T1120 punct [,15
R689 T1120 T1088 parataxis 15,reported
R690 T1121 T1120 punct ],15
R691 T1122 T1088 punct .,reported
R692 T1124 T1125 det A,study
R693 T1125 T1127 nsubj study,showed
R694 T1126 T1125 amod prior,study
R695 T1128 T1129 det a,increase
R696 T1129 T1127 dobj increase,showed
R697 T1130 T1131 quantmod 2,3
R698 T1131 T1134 quantmod 3,fold
R699 T1132 T1131 punct -,3
R700 T1133 T1131 quantmod to,3
R701 T1134 T1129 nummod fold,increase
R702 T1135 T1134 punct -,fold
R703 T1136 T1129 prep in,increase
R704 T1137 T1138 det the,number
R705 T1138 T1136 pobj number,in
R706 T1139 T1140 npadvmod S,positive
R707 T1140 T1144 amod positive,cells
R708 T1141 T1140 punct -,positive
R709 T1142 T1140 npadvmod opsin,positive
R710 T1143 T1140 punct –,positive
R711 T1144 T1138 nmod cells,number
R712 T1145 T1144 prep in,cells
R713 T1146 T1147 det the,retina
R714 T1147 T1145 pobj retina,in
R715 T1148 T1147 compound rd7,retina
R716 T1149 T1129 prep compared,increase
R717 T1150 T1149 prep to,compared
R718 T1151 T1152 amod wild,type
R719 T1152 T1150 pobj type,to
R720 T1153 T1154 punct [,17
R721 T1154 T1127 parataxis 17,showed
R722 T1155 T1154 punct ],17
R723 T1156 T1127 punct .,showed
R724 T1158 T1159 prep In,reported
R725 T1160 T1158 pobj addition,In
R726 T1161 T1159 punct ", ",reported
R727 T1162 T1163 nummod two,groups
R728 T1163 T1159 nsubj groups,reported
R729 T1164 T1159 advmod recently,reported
R730 T1165 T1159 dobj derepression,reported
R731 T1166 T1165 prep of,derepression
R732 T1167 T1168 amod additional,genes
R733 T1168 T1166 pobj genes,of
R734 T1169 T1168 compound cone,genes
R735 T1170 T1165 prep in,derepression
R736 T1171 T1172 det the,mutant
R737 T1172 T1170 pobj mutant,in
R738 T1173 T1172 compound rd7,mutant
R739 T1174 T1175 punct [,19
R740 T1175 T1159 parataxis 19,reported
R741 T1176 T1175 nummod 18,19
R742 T1177 T1175 punct ",",19
R743 T1178 T1175 punct ],19
R744 T1179 T1159 punct .,reported
R745 T1181 T1182 prep In,undertook
R746 T1183 T1181 pobj order,In
R747 T1184 T1185 aux to,understand
R748 T1185 T1183 acl understand,order
R749 T1186 T1185 advmod better,understand
R750 T1187 T1188 det the,basis
R751 T1188 T1185 dobj basis,understand
R752 T1189 T1188 amod mechanistic,basis
R753 T1190 T1188 prep of,basis
R754 T1191 T1190 pobj ESCS,of
R755 T1192 T1182 punct ", ",undertook
R756 T1193 T1182 nsubj we,undertook
R757 T1194 T1195 det a,analysis
R758 T1195 T1182 dobj analysis,undertook
R759 T1196 T1195 amod molecular,analysis
R760 T1197 T1196 cc and,molecular
R761 T1198 T1196 conj ultrastructural,molecular
R762 T1199 T1195 prep of,analysis
R763 T1200 T1201 det the,photoreceptors
R764 T1201 T1199 pobj photoreceptors,of
R765 T1202 T1201 prep of,photoreceptors
R766 T1203 T1204 det the,mouse
R767 T1204 T1202 pobj mouse,of
R768 T1205 T1204 compound rd7,mouse
R769 T1206 T1204 compound mutant,mouse
R770 T1207 T1182 punct .,undertook
R771 T1209 T1210 nmod Microarray,analyses
R772 T1210 T1215 nsubj analyses,revealed
R773 T1211 T1209 cc and,Microarray
R774 T1212 T1213 advmod in,situ
R775 T1213 T1214 amod situ,hybridization
R776 T1214 T1209 conj hybridization,Microarray
R777 T1216 T1217 det a,increase
R778 T1217 T1215 dobj increase,revealed
R779 T1218 T1217 amod modest,increase
R780 T1219 T1217 prep in,increase
R781 T1220 T1221 det the,number
R782 T1221 T1219 pobj number,in
R783 T1222 T1221 prep of,number
R784 T1223 T1224 npadvmod S,positive
R785 T1224 T1228 amod positive,cells
R786 T1225 T1223 punct -,S
R787 T1226 T1223 amod opsin,S
R788 T1227 T1224 punct –,positive
R789 T1228 T1222 pobj cells,of
R790 T1229 T1228 cc and,cells
R791 T1230 T1231 amod widespread,derepression
R792 T1231 T1228 conj derepression,cells
R793 T1232 T1231 prep of,derepression
R794 T1233 T1234 amod many,genes
R795 T1234 T1232 pobj genes,of
R796 T1235 T1236 npadvmod cone,specific
R797 T1236 T1234 amod specific,genes
R798 T1237 T1236 punct -,specific
R799 T1238 T1215 prep within,revealed
R800 T1239 T1240 compound rod,cells
R801 T1240 T1238 pobj cells,within
R802 T1241 T1240 compound photoreceptor,cells
R803 T1242 T1215 punct .,revealed
R804 T1244 T1245 amod Ultrastructural,studies
R805 T1245 T1246 nsubj studies,demonstrated
R806 T1247 T1248 mark that,represent
R807 T1248 T1246 ccomp represent,demonstrated
R808 T1249 T1250 det the,cells
R809 T1250 T1248 nsubj cells,represent
R810 T1251 T1252 dep that,coexpress
R811 T1252 T1250 relcl coexpress,cells
R812 T1253 T1254 nmod rod,genes
R813 T1254 T1252 dobj genes,coexpress
R814 T1255 T1253 cc and,rod
R815 T1256 T1253 conj cone,rod
R816 T1257 T1252 prep in,coexpress
R817 T1258 T1259 det the,retina
R818 T1259 T1257 pobj retina,in
R819 T1260 T1259 compound rd7,retina
R820 T1261 T1262 det a,type
R821 T1262 T1248 dobj type,represent
R822 T1263 T1264 advmod morphologically,hybrid
R823 T1264 T1262 amod hybrid,type
R824 T1265 T1262 compound cell,type
R825 T1266 T1262 punct ", ",type
R826 T1267 T1262 amod intermediate,type
R827 T1268 T1267 prep between,intermediate
R828 T1269 T1270 amod normal,rods
R829 T1270 T1268 pobj rods,between
R830 T1271 T1270 cc and,rods
R831 T1272 T1270 conj cones,rods
R832 T1273 T1246 punct .,demonstrated

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T620 24-28 CL:0000573 denotes cone
T621 70-84 CL:0000210 denotes photoreceptors
T622 130-133 CL:0000604 denotes rod
T623 246-261 GO:1990603 denotes dark adaptation
T624 361-370 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T625 378-384 SO:0000910 denotes orphan
T626 385-392 GO:0005634 denotes nuclear
T627 393-401 GO_EXT:0004872 denotes receptor
T628 402-415 GO_EXT:transcription denotes transcription
T629 402-422 GO_EXT:transcription_factor denotes transcription factor
T630 423-428 PR_EXT:000011403 denotes NR2E3
T631 444-457 CL:0000210 denotes photoreceptor
T632 444-474 PR_EXT:000011403 denotes photoreceptor nuclear receptor
T633 458-465 GO:0005634 denotes nuclear
T634 466-474 GO_EXT:0004872 denotes receptor
T635 486-495 GO:0010467 denotes expressed
T636 511-515 CL:0000604 denotes rods
T637 530-535 NCBITaxon:9606 denotes human
T638 536-543 SO_EXT:0000704 denotes genetic
T639 575-584 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T640 593-597 SO_EXT:0000704 denotes gene
T641 651-661 CHEBI_EXT:26130 denotes pigmentary
T642 662-669 UBERON:0000966 denotes retinal
T643 786-803 CL:0000604 denotes rod photoreceptor
T644 962-966 _FRAGMENT denotes blue
T645 974-988 CL:0000495 denotes photoreceptors
T646 969-988 CL:0000573 denotes cone photoreceptors
T647 992-997 CL:0000573 denotes cones
T648 1059-1065 UBERON:0000966 denotes retina
T649 1073-1078 NCBITaxon:9606 denotes human
T650 1111-1118 UBERON:0000966 denotes retinal
T651 1159-1168 PR_EXT:000001245 denotes rhodopsin
T652 1178-1183 CL_GO_EXT:cell denotes cells
T653 1217-1229 PR_EXT:000001195 denotes S-cone opsin
T654 1219-1223 CL:0000573 denotes cone
T655 1230-1240 GO:0010467 denotes expressing
T656 1241-1246 CL_GO_EXT:cell denotes cells
T657 1285-1290 CL:0000573 denotes cones
T658 1552-1559 UBERON:0000966 denotes retinas
T659 1590-1609 UBERON:0001789 denotes outer nuclear layer
T660 1596-1603 GO:0005634 denotes nuclear
T661 1611-1614 UBERON:0001789 denotes ONL
T662 1622-1635 CL:0000210 denotes photoreceptor
T663 1636-1640 CL_GO_EXT:cell denotes cell
T664 1636-1647 GO:0044297 denotes cell bodies
T665 1667-1674 UBERON:0000966 denotes retinal
T666 1744-1753 SO_EXT:sequence_alteration_entity_or_process denotes Mutations
T667 1761-1766 NCBITaxon:10088 denotes mouse
T668 1767-1775 SO_EXT:0000855 denotes ortholog
T669 1779-1784 PR_EXT:000011403 denotes NR2E3
T670 1825-1831 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T671 1832-1839 UBERON:0000966 denotes retinal
T672 1872-1878 SO_EXT:sequence_altered_entity denotes mutant
T673 1897-1904 UBERON:0000966 denotes retinal
T674 1949-1952 UBERON:0001789 denotes ONL
T675 2011-2016 NCBITaxon:10088 denotes mouse
T676 2038-2053 GO:1990603 denotes dark adaptation
T677 2160-2164 CL_GO_EXT:cell denotes cell
T678 2235-2242 PR_EXT:000001195 denotes S-opsin
T679 2252-2257 CL_GO_EXT:cell denotes cells
T680 2269-2275 UBERON:0000966 denotes retina
T681 2288-2297 SO_EXT:wild_type_entity_or_quality denotes wild type
T682 2373-2377 CL:0000573 denotes cone
T683 2378-2383 SO_EXT:0000704 denotes genes
T684 2395-2401 SO_EXT:sequence_altered_entity denotes mutant
T685 2487-2496 CHEBI_EXT:polyatomic_entity_or_group denotes molecular
T686 2533-2547 CL:0000210 denotes photoreceptors
T687 2559-2565 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T688 2566-2571 NCBITaxon:10088 denotes mouse
T689 2596-2609 GO:0097617 denotes hybridization
T690 2663-2670 PR_EXT:000001195 denotes S-opsin
T691 2680-2685 CL_GO_EXT:cell denotes cells
T692 2722-2726 CL:0000573 denotes cone
T693 2736-2741 SO_EXT:0000704 denotes genes
T694 2749-2772 CL:0000604 denotes rod photoreceptor cells
T695 2767-2772 CL_GO_EXT:cell denotes cells
T696 2820-2825 CL_GO_EXT:cell denotes cells
T697 2833-2840 GO:0010467 denotes express
T698 2841-2844 CL:0000604 denotes rod
T699 2849-2853 CL:0000573 denotes cone
T700 2854-2859 SO_EXT:0000704 denotes genes
T701 2871-2877 UBERON:0000966 denotes retina
T702 2913-2917 CL_GO_EXT:cell denotes cell
T703 2952-2956 CL:0000604 denotes rods
T704 2961-2966 CL:0000573 denotes cones
R294 T645 T644 _lexicallyChainedTo photoreceptors,blue

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T557 24-28 CL:0000573 denotes cone
T558 70-84 CL:0000210 denotes photoreceptors
T559 130-133 CL:0000604 denotes rod
T560 246-261 GO:1990603 denotes dark adaptation
T561 378-384 SO:0000910 denotes orphan
T562 385-392 GO:0005634 denotes nuclear
T563 423-428 PR:000011403 denotes NR2E3
T564 444-457 CL:0000210 denotes photoreceptor
T565 444-474 PR:000011403 denotes photoreceptor nuclear receptor
T566 458-465 GO:0005634 denotes nuclear
T567 486-495 GO:0010467 denotes expressed
T568 511-515 CL:0000604 denotes rods
T569 530-535 NCBITaxon:9606 denotes human
T570 536-543 SO:0000704 denotes genetic
T571 593-597 SO:0000704 denotes gene
T572 651-661 CHEBI:26130 denotes pigmentary
T573 662-669 UBERON:0000966 denotes retinal
T574 786-803 CL:0000604 denotes rod photoreceptor
T575 962-966 _FRAGMENT denotes blue
T576 974-988 CL:0000495 denotes photoreceptors
T577 969-988 CL:0000573 denotes cone photoreceptors
T578 992-997 CL:0000573 denotes cones
T579 1059-1065 UBERON:0000966 denotes retina
T580 1073-1078 NCBITaxon:9606 denotes human
T581 1111-1118 UBERON:0000966 denotes retinal
T582 1159-1168 PR:000001245 denotes rhodopsin
T583 1217-1229 PR:000001195 denotes S-cone opsin
T584 1219-1223 CL:0000573 denotes cone
T585 1230-1240 GO:0010467 denotes expressing
T586 1285-1290 CL:0000573 denotes cones
T587 1552-1559 UBERON:0000966 denotes retinas
T588 1590-1609 UBERON:0001789 denotes outer nuclear layer
T589 1596-1603 GO:0005634 denotes nuclear
T590 1611-1614 UBERON:0001789 denotes ONL
T591 1622-1635 CL:0000210 denotes photoreceptor
T592 1636-1647 GO:0044297 denotes cell bodies
T593 1667-1674 UBERON:0000966 denotes retinal
T594 1761-1766 NCBITaxon:10088 denotes mouse
T595 1767-1775 SO:0000855 denotes ortholog
T596 1779-1784 PR:000011403 denotes NR2E3
T597 1832-1839 UBERON:0000966 denotes retinal
T598 1897-1904 UBERON:0000966 denotes retinal
T599 1949-1952 UBERON:0001789 denotes ONL
T600 2011-2016 NCBITaxon:10088 denotes mouse
T601 2038-2053 GO:1990603 denotes dark adaptation
T602 2235-2242 PR:000001195 denotes S-opsin
T603 2269-2275 UBERON:0000966 denotes retina
T604 2373-2377 CL:0000573 denotes cone
T605 2378-2383 SO:0000704 denotes genes
T606 2533-2547 CL:0000210 denotes photoreceptors
T607 2566-2571 NCBITaxon:10088 denotes mouse
T608 2596-2609 GO:0097617 denotes hybridization
T609 2663-2670 PR:000001195 denotes S-opsin
T610 2722-2726 CL:0000573 denotes cone
T611 2736-2741 SO:0000704 denotes genes
T612 2749-2772 CL:0000604 denotes rod photoreceptor cells
T613 2833-2840 GO:0010467 denotes express
T614 2841-2844 CL:0000604 denotes rod
T615 2849-2853 CL:0000573 denotes cone
T616 2854-2859 SO:0000704 denotes genes
T617 2871-2877 UBERON:0000966 denotes retina
T618 2952-2956 CL:0000604 denotes rods
T619 2961-2966 CL:0000573 denotes cones
R293 T576 T575 _lexicallyChainedTo photoreceptors,blue

2_test

Id Subject Object Predicate Lexical cue
16110338-2335450-85798498 330-331 2335450 denotes 1
16110338-7645276-85798499 332-333 7645276 denotes 2
16110338-10655056-85798500 517-518 10655056 denotes 3
16110338-15277507-85798501 519-520 15277507 denotes 4
16110338-12963616-85798502 684-685 12963616 denotes 5
16110338-2787013-85798503 860-861 2787013 denotes 6
16110338-2789128-85798503 860-861 2789128 denotes 6
16110338-2335450-85798504 1018-1019 2335450 denotes 1
16110338-7645276-85798505 1020-1021 7645276 denotes 2
16110338-2012146-85798506 1022-1023 2012146 denotes 9
16110338-2378376-85798506 1022-1023 2378376 denotes 9
16110338-1743268-85798506 1022-1023 1743268 denotes 9
16110338-15229190-85798507 1736-1738 15229190 denotes 12
16110338-11773633-85798507 1736-1738 11773633 denotes 12
16110338-301373-85798507 1736-1738 301373 denotes 12
16110338-10805811-85798508 1862-1864 10805811 denotes 15
16110338-10805811-85798509 1977-1979 10805811 denotes 15
16110338-12407160-85798510 1980-1982 12407160 denotes 16
16110338-10805811-85798511 2171-2173 10805811 denotes 15
16110338-11487564-85798512 2299-2301 11487564 denotes 17
16110338-15634773-85798513 2403-2405 15634773 denotes 18
16110338-15689355-85798514 2406-2408 15689355 denotes 19
T34232 330-331 2335450 denotes 1
T59131 332-333 7645276 denotes 2
T82344 517-518 10655056 denotes 3
T22466 519-520 15277507 denotes 4
T58203 684-685 12963616 denotes 5
T14338 860-861 2787013 denotes 6
T26432 860-861 2789128 denotes 6
T77085 1018-1019 2335450 denotes 1
T40817 1020-1021 7645276 denotes 2
T88637 1022-1023 2012146 denotes 9
T68689 1022-1023 2378376 denotes 9
T15477 1022-1023 1743268 denotes 9
T72997 1736-1738 15229190 denotes 12
T6341 1736-1738 11773633 denotes 12
T19811 1736-1738 301373 denotes 12
T9696 1862-1864 10805811 denotes 15
T89145 1977-1979 10805811 denotes 15
T79486 1980-1982 12407160 denotes 16
T51616 2171-2173 10805811 denotes 15
T88805 2299-2301 11487564 denotes 17
T72364 2403-2405 15634773 denotes 18
T45111 2406-2408 15689355 denotes 19