PMC:1186732 / 25947-26459 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1186732","sourcedb":"PMC","sourceid":"1186732","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1186732","text":"Strikingly, Nr2e3 itself was markedly up-regulated in the rd7 mutant both by microarray and in situ hybridization (see Figure 2, lower right photomicrographs; Table S2). The rd7 mutant carries a deletion in Nr2e3 that removes portions of both the DNA-binding and ligand-binding domains [15]. Although this deletion most likely creates a null allele, a residual transcript is clearly present and up-regulated in the rd7 mutant. 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