
PMC:1183529
Annnotations
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T897 | 28-37 | UBERON:0001103 | denotes | Diaphragm |
T898 | 28-37 | _FRAGMENT | denotes | Diaphragm |
T899 | 47-58 | GO:0060539 | denotes | Development |
T900 | 42-46 | UBERON:0002048 | denotes | Lung |
T901 | 42-58 | GO:0030324 | denotes | Lung Development |
T902 | 62-66 | NCBITaxon:10088 | denotes | Mice |
T903 | 71-77 | NCBITaxon:9606 | denotes | Humans |
T904 | 148-161 | UBERON:0001103 | denotes | diaphragmatic |
T905 | 190-203 | UBERON:0001103 | denotes | diaphragmatic |
T906 | 379-386 | UBERON:0000922 | denotes | embryos |
T907 | 400-404 | NCBITaxon:10088 | denotes | mice |
T908 | 418-439 | CHEBI:23995 | denotes | N-ethyl-N-nitrosourea |
T909 | 478-487 | UBERON:0002048 | denotes | pulmonary |
T910 | 512-525 | UBERON:0001103 | denotes | diaphragmatic |
T911 | 512-537 | GO:0060539 | denotes | diaphragmatic development |
T912 | 539-543 | PR:000017653 | denotes | Fog2 |
T913 | 545-550 | PR:000017653 | denotes | Zfpm2 |
T914 | 602-623 | CHEBI:23995 | denotes | N-ethyl-N-nitrosourea |
T915 | 664-668 | PR:000017653 | denotes | Fog2 |
T916 | 696-702 | GO:0008380 | denotes | splice |
T917 | 741-751 | SO:0000673 | denotes | transcript |
T918 | 782-787 | NCBITaxon:9606 | denotes | Human |
T919 | 807-820 | UBERON:0001103 | denotes | diaphragmatic |
T920 | 832-841 | UBERON:0002048 | denotes | pulmonary |
T921 | 885-889 | PR:000017653 | denotes | FOG2 |
T922 | 952-972 | SO:0001587 | denotes | premature stop codon |
T923 | 988-992 | GO:0016265 | denotes | died |
T924 | 1013-1017 | UBERON:0000104 | denotes | life |
T925 | 1048-1057 | UBERON:0002048 | denotes | pulmonary |
T926 | 1100-1109 | UBERON:0001103 | denotes | diaphragm |
T927 | 1171-1175 | PR:000017653 | denotes | Fog2 |
T928 | 1199-1208 | UBERON:0001103 | denotes | diaphragm |
T929 | 1213-1217 | UBERON:0002048 | denotes | lung |
T930 | 1213-1229 | GO:0030324 | denotes | lung development |
T931 | 1280-1284 | PR:000017653 | denotes | FOG2 |
T932 | 1298-1302 | SO:0000704 | denotes | gene |
T933 | 1350-1355 | NCBITaxon:9606 | denotes | human |
T934 | 1367-1380 | UBERON:0001103 | denotes | diaphragmatic |
T935 | 1412-1421 | UBERON:0002048 | denotes | pulmonary |
T936 | 1412-1433 | GO:0030324 | denotes | pulmonary development |
T937 | 1489-1502 | UBERON:0001103 | denotes | diaphragmatic |
T938 | 1532-1541 | UBERON:0002048 | denotes | pulmonary |
T939 | 1532-1555 | GO:0030324 | denotes | pulmonary developmental |
T2431 | 3038-3051 | UBERON:0001103 | denotes | diaphragmatic |
T2432 | 3096-3101 | GO:0007567 | denotes | birth |
T2433 | 3184-3197 | UBERON:0001103 | denotes | diaphragmatic |
T2434 | 3293-3306 | UBERON:0001103 | denotes | diaphragmatic |
T2435 | 3328-3333 | GO:0007567 | denotes | birth |
T2436 | 3335-3348 | UBERON:0001103 | denotes | diaphragmatic |
T2437 | 3361-3374 | UBERON:0001103 | denotes | diaphragmatic |
T2438 | 3472-3480 | UBERON:0001062 | denotes | anatomic |
T2439 | 3584-3590 | GO:0016265 | denotes | mortem |
T2440 | 3605-3614 | UBERON:0002048 | denotes | Pulmonary |
T2441 | 3648-3661 | UBERON:0001103 | denotes | diaphragmatic |
T2442 | 3765-3778 | UBERON:0001103 | denotes | diaphragmatic |
T2443 | 3791-3800 | UBERON:0002048 | denotes | pulmonary |
T2444 | 3878-3887 | UBERON:0002048 | denotes | pulmonary |
T2445 | 4123-4129 | GO:0016265 | denotes | deaths |
T2446 | 4139-4144 | GO:0007567 | denotes | birth |
T2447 | 4240-4251 | UBERON:0001004 | denotes | respiratory |
T2448 | 4263-4268 | GO:0007567 | denotes | birth |
T2449 | 4388-4392 | UBERON:0002048 | denotes | lung |
T2450 | 4425-4436 | GO:0015671 | denotes | oxygenation |
T2451 | 4695-4706 | UBERON:0001004 | denotes | respiratory |
T2452 | 4722-4731 | GO:0050890 | denotes | cognitive |
T2453 | 4736-4746 | GO:0050905 | denotes | neuromotor |
T2454 | 4761-4768 | GO:0007605 | denotes | hearing |
T2455 | 4990-5003 | UBERON:0001103 | denotes | diaphragmatic |
T2456 | 5016-5025 | UBERON:0002048 | denotes | pulmonary |
T2457 | 5040-5046 | NCBITaxon:9606 | denotes | humans |
T2458 | 5199-5206 | SO:0000704 | denotes | genetic |
T2459 | 5357-5370 | UBERON:0001103 | denotes | diaphragmatic |
T2460 | 5357-5382 | GO:0060539 | denotes | diaphragmatic development |
T2461 | 5574-5580 | NCBITaxon:9606 | denotes | humans |
T2462 | 5626-5632 | NCBITaxon:33208 | denotes | animal |
T2463 | 5643-5648 | NCBITaxon:9606 | denotes | human |
T2464 | 5649-5654 | GO:0007567 | denotes | birth |
T2465 | 5680-5687 | SO:0000704 | denotes | genetic |
T2466 | 5711-5717 | NCBITaxon:33208 | denotes | animal |
T2467 | 5753-5758 | NCBITaxon:9606 | denotes | human |
T2468 | 5784-5788 | NCBITaxon:10088 | denotes | mice |
T2469 | 5815-5822 | CHEBI:25435 | denotes | mutagen |
T2470 | 5823-5844 | CHEBI:23995 | denotes | N-ethyl-N-nitrosourea |
T2471 | 5846-5849 | CHEBI:23995 | denotes | ENU |
T2472 | 5908-5924 | UBERON:0012101 | denotes | perinatal period |
T2473 | 5912-5917 | GO:0007567 | denotes | natal |
T2474 | 5973-5977 | NCBITaxon:10088 | denotes | mice |
T2475 | 6032-6041 | UBERON:0002048 | denotes | pulmonary |
T2476 | 6066-6079 | UBERON:0001103 | denotes | diaphragmatic |
T2477 | 6066-6079 | _FRAGMENT | denotes | diaphragmatic |
T2478 | 6092-6103 | GO:0060539 | denotes | development |
T2479 | 6084-6091 | UBERON:0000948 | denotes | cardiac |
T2480 | 6084-6103 | GO:0007507 | denotes | cardiac development |
T2481 | 6144-6148 | PR:000017653 | denotes | Fog2 |
T2482 | 6150-6155 | PR:000017653 | denotes | Zfpm2 |
T2483 | 6224-6230 | GO:0008380 | denotes | splice |
T2484 | 6269-6279 | SO:0000673 | denotes | transcript |
T2485 | 6352-6363 | SO:0000858 | denotes | orthologous |
T2486 | 6364-6368 | SO:0000704 | denotes | gene |
T2487 | 6372-6378 | NCBITaxon:9606 | denotes | humans |
T2488 | 6475-6479 | PR:000017653 | denotes | FOG2 |
T2489 | 6497-6501 | GO:0016265 | denotes | died |
T2490 | 6505-6510 | GO:0007567 | denotes | birth |
T2491 | 6518-6531 | UBERON:0001103 | denotes | diaphragmatic |
T2492 | 6550-6559 | UBERON:0002048 | denotes | pulmonary |
T2493 | 6649-6654 | NCBITaxon:9606 | denotes | human |
T2494 | 6717-6726 | UBERON:0002048 | denotes | pulmonary |
T5066 | 6835-6839 | UBERON:0002048 | denotes | lung |
T5067 | 6852-6856 | PR:000017653 | denotes | Fog2 |
T5068 | 6897-6900 | CHEBI:23995 | denotes | ENU |
T5069 | 6913-6917 | NCBITaxon:10088 | denotes | mice |
T5070 | 6921-6930 | UBERON:0000922 | denotes | embryonic |
T5071 | 7004-7008 | NCBITaxon:10088 | denotes | mice |
T5072 | 7036-7043 | UBERON:0000922 | denotes | embryos |
T5073 | 7082-7091 | UBERON:0002048 | denotes | pulmonary |
T5074 | 7114-7123 | UBERON:0001103 | denotes | diaphragm |
T5075 | 7162-7166 | UBERON:0002048 | denotes | lung |
T5076 | 7238-7247 | SO:0001024 | denotes | haplotype |
T5077 | 7410-7414 | NCBITaxon:10088 | denotes | mice |
T5078 | 7754-7762 | SO:0000357 | denotes | flanking |
T5079 | 7832-7841 | UBERON:0002048 | denotes | pulmonary |
T5080 | 7869-7878 | UBERON:0001103 | denotes | diaphragm |
T5081 | 7880-7889 | UBERON:0002048 | denotes | Pulmonary |
T5082 | 7928-7932 | NCBITaxon:10088 | denotes | mice |
T5083 | 7950-7955 | GO:0007567 | denotes | birth |
T5084 | 8002-8006 | NCBITaxon:10088 | denotes | mice |
T5085 | 8032-8036 | UBERON:0000104 | denotes | life |
T5086 | 8084-8088 | UBERON:0002048 | denotes | lung |
T5087 | 8136-8140 | NCBITaxon:10088 | denotes | mice |
T5088 | 8161-8165 | UBERON:0002048 | denotes | lung |
T5089 | 8218-8222 | UBERON:0002048 | denotes | lung |
T5090 | 8265-8270 | UBERON:0002048 | denotes | lungs |
T5091 | 8283-8287 | NCBITaxon:10088 | denotes | mice |
T5092 | 8314-8318 | UBERON:0009912 | denotes | lobe |
T5093 | 8391-8395 | UBERON:0009912 | denotes | lobe |
T5094 | 8409-8419 | UBERON:0001103 | denotes | Diaphragms |
T5095 | 8436-8440 | NCBITaxon:10088 | denotes | mice |
T5096 | 8508-8518 | CL:0002372 | denotes | Myotubules |
T5097 | 8591-8601 | CL:0002372 | denotes | myotubules |
T5098 | 8665-8675 | UBERON:0000309 | denotes | body walls |
T5099 | 8702-8715 | CL:0000187 | denotes | muscle fibers |
T5100 | 8723-8740 | UBERON:0006670 | denotes | central tendonous |
T5101 | 8763-8772 | UBERON:0001103 | denotes | diaphragm |
T5102 | 8774-8784 | CL:0002372 | denotes | myotubules |
T5103 | 8831-8844 | UBERON:0002385 | denotes | muscle tissue |
T5104 | 8884-8894 | UBERON:0000309 | denotes | body walls |
T5105 | 9389-9393 | NCBITaxon:10088 | denotes | mice |
T5106 | 9411-9416 | GO:0007567 | denotes | birth |
T5107 | 9541-9550 | UBERON:0000922 | denotes | embryonic |
T5108 | 9620-9627 | UBERON:0000995 | denotes | uterine |
T5109 | 9628-9634 | GO:0016265 | denotes | demise |
T5110 | 9701-9708 | UBERON:0000922 | denotes | embryos |
T5111 | 9760-9767 | UBERON:0000995 | denotes | uterine |
T5112 | 9768-9774 | GO:0016265 | denotes | demise |
T5113 | 9818-9824 | UBERON:0000479 | denotes | tissue |
T5114 | 9841-9848 | UBERON:0000922 | denotes | embryos |
T5115 | 9884-9890 | GO:0016265 | denotes | demise |
T5116 | 10062-10066 | GO:0016265 | denotes | died |
T5117 | 10136-10143 | UBERON:0000922 | denotes | embryos |
T5118 | 10167-10171 | GO:0016265 | denotes | died |
T5119 | 10194-10201 | UBERON:0000922 | denotes | embryos |
T5120 | 10260-10266 | UBERON:0000922 | denotes | embryo |
T5121 | 10279-10292 | UBERON:0001103 | denotes | Diaphragmatic |
T5122 | 10336-10340 | NCBITaxon:10088 | denotes | mice |
T5123 | 10360-10369 | UBERON:0002048 | denotes | Pulmonary |
T5125 | 10491-10498 | UBERON:0000948 | denotes | cardiac |
T5126 | 10522-10528 | UBERON:0000948 | denotes | hearts |
T5127 | 10551-10555 | NCBITaxon:10088 | denotes | mice |
T5128 | 10640-10660 | UBERON:0002062 | denotes | endocardial cushions |
T5129 | 10671-10677 | UBERON:0004145 | denotes | outlet |
T5130 | 10678-10693 | UBERON:0002080 | denotes | right ventricle |
T5131 | 10710-10732 | UBERON:0002087 | denotes | atrioventricular canal |
T5132 | 10738-10748 | UBERON:0002349 | denotes | myocardium |
T5133 | 10803-10816 | UBERON:0004125 | denotes | compact layer |
T5134 | 10865-10869 | NCBITaxon:10088 | denotes | mice |
T5135 | 10887-10892 | GO:0007567 | denotes | birth |
T5136 | 10902-10909 | UBERON:0000948 | denotes | cardiac |
T5137 | 10934-10956 | UBERON:0002087 | denotes | atrioventricular-canal |
T5138 | 10962-10980 | UBERON:0002094 | denotes | ventricular septal |
T5139 | 10990-11003 | UBERON:0009149 | denotes | ostium primum |
T5140 | 11004-11017 | UBERON:0002085 | denotes | atrial septal |
T5141 | 11040-11045 | UBERON:0002081 | denotes | atria |
T5142 | 11105-11112 | UBERON:0000948 | denotes | cardiac |
T5143 | 11145-11152 | UBERON:0000948 | denotes | cardiac |
T5144 | 11145-11164 | GO:0007507 | denotes | cardiac development |
T5145 | 11267-11282 | SO:0000996 | denotes | predicted genes |
T5146 | 11298-11303 | SO:0000704 | denotes | genes |
T5147 | 11315-11319 | PR:000017653 | denotes | Fog2 |
T5148 | 11343-11347 | PR:000017653 | denotes | Fog2 |
T5149 | 11353-11360 | UBERON:0000948 | denotes | cardiac |
T5150 | 11425-11429 | NCBITaxon:10088 | denotes | mice |
T5151 | 11441-11463 | UBERON:0002087 | denotes | atrioventricular canal |
T5152 | 11481-11491 | UBERON:0002349 | denotes | myocardium |
T5153 | 11504-11512 | UBERON:0005985 | denotes | coronary |
T5154 | 11513-11524 | UBERON:0002049 | denotes | vasculature |
T5155 | 11579-11583 | PR:000017653 | denotes | Fog2 |
T5156 | 11600-11611 | SO:0000673 | denotes | transcripts |
T5157 | 11652-11659 | UBERON:0000922 | denotes | embryos |
T5158 | 11698-11708 | SO:0000673 | denotes | transcript |
T5159 | 11764-11766 | SO:0000028 | denotes | bp |
T5160 | 11803-11809 | GO:0008380 | denotes | splice |
T5161 | 11845-11849 | SO:0000147 | denotes | exon |
T5162 | 11874-11882 | GO:0008380 | denotes | splicing |
T5163 | 11926-11928 | SO:0000028 | denotes | bp |
T5164 | 11932-11940 | SO:0000188 | denotes | intronic |
T5165 | 11966-11976 | SO:0000673 | denotes | transcript |
T5166 | 11995-12005 | SO:0000319 | denotes | stop codon |
T5167 | 12095-12099 | NCBITaxon:10088 | denotes | mice |
T5168 | 12120-12124 | PR:000017653 | denotes | Fog2 |
T5169 | 12135-12141 | SO:0001023 | denotes | allele |
T5170 | 12163-12167 | SO:0000704 | denotes | gene |
T5171 | 12204-12208 | NCBITaxon:10088 | denotes | mice |
T5172 | 12216-12225 | UBERON:0000922 | denotes | embryonic |
T5173 | 12304-12308 | PR:000017653 | denotes | Fog2 |
T5174 | 12340-12344 | NCBITaxon:10088 | denotes | mice |
T5175 | 12377-12381 | PR:000017653 | denotes | Fog2 |
T5176 | 12452-12462 | SO:0000673 | denotes | transcript |
T5177 | 12491-12497 | GO:0008380 | denotes | splice |
T5178 | 12491-12502 | SO:0000162 | denotes | splice site |
T7827 | 12938-12942 | UBERON:0002048 | denotes | Lung |
T7828 | 12938-12942 | _FRAGMENT | denotes | Lung |
T7829 | 12957-12968 | GO:0030324 | denotes | Development |
T7830 | 12947-12956 | UBERON:0001103 | denotes | Diaphragm |
T7831 | 12947-12968 | GO:0060539 | denotes | Diaphragm Development |
T7832 | 12976-12980 | PR:000017653 | denotes | Fog2 |
T7833 | 12988-12993 | NCBITaxon:10088 | denotes | Mouse |
T7834 | 13045-13049 | PR:000017653 | denotes | Fog2 |
T7835 | 13053-13062 | UBERON:0002048 | denotes | pulmonary |
T7836 | 13053-13062 | _FRAGMENT | denotes | pulmonary |
T7837 | 13081-13092 | GO:0030324 | denotes | development |
T7838 | 13067-13080 | UBERON:0001103 | denotes | diaphragmatic |
T7839 | 13067-13092 | GO:0060539 | denotes | diaphragmatic development |
T7840 | 13098-13107 | UBERON:0002048 | denotes | pulmonary |
T7841 | 13192-13196 | UBERON:0009912 | denotes | lobe |
T7842 | 13231-13235 | UBERON:0009912 | denotes | lobe |
T7843 | 13289-13302 | UBERON:0001103 | denotes | diaphragmatic |
T7844 | 13289-13314 | GO:0060539 | denotes | diaphragmatic development |
T7845 | 13360-13369 | UBERON:0002048 | denotes | pulmonary |
T7846 | 13467-13471 | PR:000017653 | denotes | Fog2 |
T7847 | 13475-13484 | GO:0010467 | denotes | expressed |
T7848 | 13502-13522 | UBERON:0004883 | denotes | pulmonary mesenchyme |
T7849 | 13544-13567 | GO:0001763 | denotes | branching morphogenesis |
T7850 | 13581-13591 | GO:0010467 | denotes | expression |
T7851 | 13613-13627 | UBERON:0001135 | denotes | smooth muscles |
T7852 | 13631-13638 | UBERON:0001005 | denotes | airways |
T7853 | 13643-13652 | UBERON:0002048 | denotes | pulmonary |
T7854 | 13653-13660 | UBERON:0000055 | denotes | vessels |
T7855 | 13704-13709 | UBERON:0002048 | denotes | lungs |
T7856 | 13767-13780 | UBERON:0001103 | denotes | diaphragmatic |
T7857 | 13828-13837 | UBERON:0002048 | denotes | pulmonary |
T7858 | 13877-13890 | UBERON:0001103 | denotes | diaphragmatic |
T7859 | 13924-13929 | UBERON:0002048 | denotes | lungs |
T7860 | 13950-13954 | PR:000017653 | denotes | Fog2 |
T7861 | 13959-13963 | NCBITaxon:10088 | denotes | mice |
T7862 | 14014-14027 | UBERON:0001103 | denotes | diaphragmatic |
T7863 | 14036-14040 | PR:000017653 | denotes | Fog2 |
T7864 | 14045-14049 | NCBITaxon:10088 | denotes | mice |
T7865 | 14168-14173 | UBERON:0002048 | denotes | Lungs |
T7866 | 14196-14200 | PR:000017653 | denotes | Fog2 |
T7867 | 14205-14212 | UBERON:0000922 | denotes | embryos |
T7868 | 14277-14281 | UBERON:0009912 | denotes | lobe |
T7869 | 14296-14300 | PR:000017653 | denotes | Fog2 |
T7870 | 14305-14309 | UBERON:0002048 | denotes | lung |
T7871 | 14372-14376 | UBERON:0009912 | denotes | lobe |
T7872 | 14404-14409 | UBERON:0002048 | denotes | lungs |
T7873 | 14530-14539 | UBERON:0002048 | denotes | pulmonary |
T7874 | 14554-14558 | PR:000017653 | denotes | Fog2 |
T7875 | 14566-14570 | NCBITaxon:10088 | denotes | mice |
T7876 | 15232-15237 | UBERON:0009912 | denotes | lobes |
T7877 | 15347-15352 | UBERON:0009912 | denotes | lobes |
T7878 | 15388-15392 | PR:000017653 | denotes | Fog2 |
T7879 | 15428-15433 | UBERON:0009912 | denotes | lobar |
T7880 | 15463-15467 | PR:000017653 | denotes | Fog2 |
T7881 | 15468-15478 | GO:0010467 | denotes | expression |
T7882 | 15503-15510 | UBERON:0000922 | denotes | embryos |
T7883 | 15538-15543 | UBERON:0009912 | denotes | lobar |
T7884 | 15579-15583 | PR:000017653 | denotes | Fog2 |
T7885 | 15584-15594 | GO:0010467 | denotes | expression |
T7886 | 15630-15635 | UBERON:0009912 | denotes | lobar |
T7887 | 15642-15652 | GO:0010467 | denotes | Expression |
T7888 | 15670-15674 | NCBITaxon:10088 | denotes | mice |
T7889 | 15686-15690 | PR:000033987 | denotes | lacZ |
T7890 | 15691-15695 | SO:0000704 | denotes | gene |
T7891 | 15718-15722 | PR:000017653 | denotes | Fog2 |
T7892 | 15770-15774 | NCBITaxon:10088 | denotes | mice |
T7893 | 15798-15803 | UBERON:0002048 | denotes | lungs |
T7894 | 15837-15841 | PR:000017653 | denotes | Fog2 |
T7895 | 15842-15852 | GO:0010467 | denotes | expression |
T7896 | 15860-15870 | UBERON:0003104 | denotes | mesenchyme |
T7897 | 15922-15926 | UBERON:0009912 | denotes | lobe |
T7898 | 15946-15951 | UBERON:0009912 | denotes | lobes |
T7899 | 15984-15988 | PR:000017653 | denotes | Fog2 |
T7900 | 15996-16000 | NCBITaxon:10088 | denotes | mice |
T7901 | 16023-16033 | GO:0010467 | denotes | expression |
T7902 | 16053-16073 | UBERON:0004883 | denotes | pulmonary mesenchyme |
T7903 | 16111-16124 | GO:0097617 | denotes | hybridization |
T7904 | 16128-16134 | UBERON:0000479 | denotes | tissue |
T7905 | 16419-16429 | UBERON:0001103 | denotes | Diaphragms |
T7906 | 16435-16439 | PR:000017653 | denotes | Fog2 |
T7907 | 16444-16448 | NCBITaxon:10088 | denotes | mice |
T7908 | 16557-16566 | UBERON:0001103 | denotes | diaphragm |
T7909 | 16609-16631 | CL:0000680 | denotes | muscle precursor cells |
T7910 | 16647-16652 | UBERON:0002101 | denotes | limbs |
T7911 | 16662-16666 | NCBITaxon:10088 | denotes | Mice |
T7912 | 16683-16688 | SO:0000704 | denotes | genes |
T7913 | 16719-16726 | GO:0065007 | denotes | control |
T7914 | 16769-16779 | UBERON:0001103 | denotes | diaphragms |
T7915 | 16792-16802 | CL:0000182 | denotes | Hepatocyte |
T7916 | 16792-16816 | PR:000008534 | denotes | Hepatocyte growth factor |
T7917 | 16817-16831 | PR:000008534 | denotes | Scatter factor |
T7918 | 16833-16836 | PR:000008534 | denotes | HGF |
T7919 | 16933-16942 | UBERON:0001103 | denotes | diaphragm |
T7920 | 16967-16970 | PR:000008534 | denotes | HGF |
T7921 | 16974-16983 | GO:0010467 | denotes | expressed |
T7922 | 16995-17003 | UBERON:0001062 | denotes | anatomic |
T7923 | 17022-17026 | NCBITaxon:10088 | denotes | mice |
T7924 | 17047-17050 | PR:000008534 | denotes | HGF |
T7925 | 17060-17065 | PR:000010335 | denotes | c-Met |
T7926 | 17092-17114 | UBERON:0009133 | denotes | pleuroperitoneal folds |
T7927 | 17116-17120 | UBERON:0009133 | denotes | PPFs |
T7928 | 17147-17157 | UBERON:0001103 | denotes | diaphragms |
T7929 | 17167-17171 | PR:000017653 | denotes | Fog2 |
T7930 | 17175-17184 | GO:0010467 | denotes | expressed |
T7931 | 17218-17227 | UBERON:0001103 | denotes | diaphragm |
T7932 | 17274-17283 | UBERON:0001103 | denotes | diaphragm |
T7933 | 17308-17312 | PR:000012316 | denotes | Pax3 |
T7934 | 17317-17321 | PR:000010875 | denotes | MyoD |
T7935 | 17443-17447 | UBERON:0009133 | denotes | PPFs |
T7936 | 17451-17455 | PR:000017653 | denotes | Fog2 |
T7937 | 17460-17464 | NCBITaxon:10088 | denotes | mice |
T7938 | 17500-17510 | GO:0010467 | denotes | expression |
T7939 | 17542-17552 | GO:0010467 | denotes | expression |
T7940 | 17556-17559 | PR:000008534 | denotes | HGF |
T7941 | 17616-17625 | UBERON:0001103 | denotes | diaphragm |
T7942 | 17650-17654 | PR:000017653 | denotes | Fog2 |
T7943 | 17662-17666 | NCBITaxon:10088 | denotes | mice |
T7944 | 17699-17703 | PR:000017653 | denotes | Fog2 |
T7945 | 17769-17772 | PR:000008534 | denotes | HGF |
T7946 | 17791-17800 | UBERON:0001103 | denotes | diaphragm |
T7947 | 17809-17819 | GO:0065007 | denotes | regulation |
T7948 | 17823-17826 | PR:000008534 | denotes | HGF |
T7949 | 17856-17877 | CL:0000680 | denotes | muscle precursor cell |
T7950 | 17873-17887 | GO:0016477 | denotes | cell migration |
T7951 | 17900-17903 | UBERON:0009133 | denotes | PPF |
T7952 | 17912-17921 | UBERON:0001103 | denotes | diaphragm |
T7953 | 17967-17971 | NCBITaxon:10088 | denotes | mice |
T9793 | 18221-18225 | PR:000017653 | denotes | FOG2 |
T9794 | 18253-18262 | UBERON:0001103 | denotes | Diaphragm |
T9795 | 18267-18271 | UBERON:0002048 | denotes | Lung |
T9796 | 18286-18290 | PR:000017653 | denotes | FOG2 |
T9797 | 18334-18340 | UBERON:0000479 | denotes | tissue |
T9798 | 18381-18389 | UBERON:0001062 | denotes | anatomic |
T9799 | 18403-18416 | UBERON:0001103 | denotes | diaphragmatic |
T9800 | 18637-18650 | UBERON:0001103 | denotes | diaphragmatic |
T9801 | 18677-18690 | UBERON:0001103 | denotes | diaphragmatic |
T9802 | 18839-18848 | UBERON:0002048 | denotes | Pulmonary |
T9803 | 18879-18883 | UBERON:0002048 | denotes | lung |
T9804 | 18913-18921 | UBERON:0003215 | denotes | alveolar |
T9805 | 19112-19116 | PR:000017653 | denotes | FOG2 |
T9806 | 19201-19212 | UBERON:0001004 | denotes | respiratory |
T9807 | 19224-19229 | GO:0007567 | denotes | birth |
T9808 | 19234-19238 | GO:0016265 | denotes | died |
T9809 | 19271-19277 | GO:0016265 | denotes | mortem |
T9810 | 19307-19311 | UBERON:0002048 | denotes | lung |
T9811 | 19332-19337 | UBERON:0000160 | denotes | bowel |
T9812 | 19345-19350 | UBERON:0001443 | denotes | chest |
T9813 | 19447-19456 | UBERON:0002048 | denotes | pulmonary |
T9814 | 19478-19482 | UBERON:0002048 | denotes | lung |
T9815 | 19582-19591 | UBERON:0002168 | denotes | left lung |
T9816 | 19597-19601 | UBERON:0002048 | denotes | lung |
T9817 | 19725-19733 | UBERON:0003215 | denotes | alveolar |
T9818 | 19791-19795 | UBERON:0002048 | denotes | lung |
T9819 | 19835-19848 | UBERON:0001103 | denotes | diaphragmatic |
T9820 | 19922-19933 | UBERON:0000211 | denotes | ligamentous |
T9821 | 19951-19964 | UBERON:0001103 | denotes | diaphragmatic |
T9822 | 19988-20000 | _FRAGMENT | denotes | left lobe of |
T9823 | 20005-20010 | UBERON:0001115 | denotes | liver |
T9824 | 20042-20047 | UBERON:0002107 | denotes | liver |
T9825 | 20088-20097 | UBERON:0001103 | denotes | diaphragm |
T9826 | 20213-20218 | UBERON:0000948 | denotes | heart |
T9827 | 20275-20280 | UBERON:0003978 | denotes | valve |
T9828 | 20362-20366 | SO:0000147 | denotes | exon |
T9829 | 20422-20432 | SO:0000319 | denotes | stop codon |
T9830 | 20520-20527 | SO:0000417 | denotes | domains |
T9831 | 20612-20618 | UBERON:0007023 | denotes | adults |
T9832 | 20887-20891 | PR:000017653 | denotes | FOG2 |
T12680 | 21289-21302 | UBERON:0001103 | denotes | diaphragmatic |
T12681 | 21411-21427 | UBERON:0012101 | denotes | perinatal period |
T12682 | 21415-21420 | GO:0007567 | denotes | natal |
T12683 | 21454-21467 | UBERON:0001103 | denotes | diaphragmatic |
T12684 | 21800-21809 | UBERON:0001103 | denotes | diaphragm |
T12685 | 21882-21887 | GO:0007567 | denotes | natal |
T12686 | 21906-21911 | GO:0007567 | denotes | natal |
T12687 | 21912-21917 | UBERON:0001443 | denotes | chest |
T12688 | 21945-21958 | UBERON:0001103 | denotes | diaphragmatic |
T12689 | 22346-22355 | UBERON:0000916 | denotes | abdominal |
T12690 | 22386-22395 | UBERON:0002048 | denotes | pulmonary |
T12691 | 22411-22422 | UBERON:0001004 | denotes | respiratory |
T12692 | 22527-22536 | UBERON:0001103 | denotes | diaphragm |
T12693 | 22560-22565 | NCBITaxon:9606 | denotes | Human |
T12694 | 22566-22570 | PR:000017653 | denotes | FOG2 |
T12695 | 22638-22647 | UBERON:0001103 | denotes | diaphragm |
T12696 | 22829-22833 | PR:000017653 | denotes | FOG2 |
T12697 | 22919-22923 | PR:000017653 | denotes | FOG2 |
T12698 | 22935-22939 | GO:0016265 | denotes | died |
T12699 | 23019-23023 | SO:0000704 | denotes | gene |
T12700 | 23174-23178 | PR:000017653 | denotes | FOG2 |
T12701 | 23235-23244 | UBERON:0002048 | denotes | pulmonary |
T12702 | 23249-23262 | UBERON:0001103 | denotes | diaphragmatic |
T12703 | 23291-23296 | NCBITaxon:10088 | denotes | mouse |
T12704 | 23301-23306 | NCBITaxon:9606 | denotes | human |
T12705 | 23341-23345 | PR:000017653 | denotes | FOG2 |
T12706 | 23379-23384 | NCBITaxon:9606 | denotes | human |
T12707 | 23399-23412 | UBERON:0001103 | denotes | diaphragmatic |
T12708 | 23417-23426 | UBERON:0002048 | denotes | pulmonary |
T12709 | 23470-23474 | NCBITaxon:10088 | denotes | mice |
T12710 | 23511-23515 | PR:000017653 | denotes | Fog2 |
T12711 | 23614-23618 | SO:0000704 | denotes | gene |
T12712 | 23679-23685 | NCBITaxon:9606 | denotes | humans |
T12713 | 23691-23695 | NCBITaxon:10088 | denotes | mice |
T12714 | 23724-23728 | PR:000017653 | denotes | Fog2 |
T12715 | 23729-23742 | UBERON:0001103 | denotes | diaphragmatic |
T12716 | 23894-23903 | UBERON:0001103 | denotes | diaphragm |
T12717 | 23929-23941 | UBERON:0004290 | denotes | dermomyotome |
T12718 | 23945-23953 | UBERON:0005434 | denotes | cervical |
T12719 | 23954-23961 | UBERON:0002329 | denotes | somites |
T12720 | 23991-24000 | UBERON:0001103 | denotes | diaphragm |
T12721 | 24020-24023 | UBERON:0009133 | denotes | PPF |
T12722 | 24040-24046 | UBERON:0000479 | denotes | tissue |
T12723 | 24085-24094 | UBERON:0000309 | denotes | body wall |
T12724 | 24102-24122 | UBERON:0003283 | denotes | esophageal mesentery |
T12725 | 24152-24170 | UBERON:0004161 | denotes | septum transversum |
T12726 | 24205-24208 | UBERON:0009133 | denotes | PPF |
T12727 | 24228-24239 | GO:0008283 | denotes | proliferate |
T12728 | 24297-24303 | UBERON:0002228 | denotes | costal |
T12729 | 24305-24312 | UBERON:0000975 | denotes | sternal |
T12730 | 24313-24319 | UBERON:0002228 | denotes | costal |
T12731 | 24325-24331 | UBERON:0000978 | denotes | crural |
T12732 | 24358-24367 | UBERON:0001103 | denotes | diaphragm |
T12733 | 24387-24390 | UBERON:0009133 | denotes | PPF |
T12734 | 24438-24450 | _FRAGMENT | denotes | formation of |
T12735 | 24455-24464 | GO:0060539 | denotes | diaphragm |
T12736 | 24455-24464 | UBERON:0001103 | denotes | diaphragm |
T12737 | 24494-24498 | PR:000017653 | denotes | Fog2 |
T12738 | 24539-24542 | PR:000008534 | denotes | HGF |
T12739 | 24543-24553 | GO:0010467 | denotes | expression |
T12740 | 24582-24604 | CL:0000680 | denotes | muscle precursor cells |
T12741 | 24633-24642 | UBERON:0001103 | denotes | diaphragm |
T12742 | 24726-24730 | PR:000017653 | denotes | Fog2 |
T12743 | 24738-24747 | UBERON:0001103 | denotes | diaphragm |
T12744 | 24758-24762 | PR:000012316 | denotes | Pax3 |
T12745 | 24767-24771 | PR:000010875 | denotes | MyoD |
T12746 | 24772-24782 | GO:0010467 | denotes | expression |
T12747 | 24802-24805 | UBERON:0009133 | denotes | PPF |
T12748 | 24868-24889 | CL:0000680 | denotes | muscle precursor cell |
T12749 | 24885-24899 | GO:0016477 | denotes | cell migration |
T12750 | 24885-24889 | _FRAGMENT | denotes | cell |
T12751 | 24904-24919 | GO:0030154 | denotes | differentiation |
T12752 | 24958-24961 | UBERON:0009133 | denotes | PPF |
T12753 | 24987-25008 | CL:0000680 | denotes | muscle precursor cell |
T12754 | 25004-25018 | GO:0016477 | denotes | cell migration |
T12755 | 25031-25034 | UBERON:0009133 | denotes | PPF |
T12756 | 25054-25063 | UBERON:0001103 | denotes | diaphragm |
T12757 | 25065-25069 | PR:000017653 | denotes | Fog2 |
T12758 | 25113-25120 | PR:000007857 | denotes | Gatas 1 |
T12759 | 25113-25118 | _FRAGMENT | denotes | Gatas |
T12760 | 25121-25122 | PR:000007861 | denotes | 6 |
T12761 | 25171-25179 | PR:000011405 | denotes | CoupTFII |
T12762 | 25208-25212 | PR:000017653 | denotes | Fog2 |
T12763 | 25213-25218 | PR:000007859 | denotes | Gata4 |
T12764 | 25254-25261 | UBERON:0000948 | denotes | cardiac |
T12765 | 25254-25261 | _FRAGMENT | denotes | cardiac |
T12766 | 25274-25285 | GO:0007507 | denotes | development |
T12767 | 25266-25273 | UBERON:0000991 | denotes | gonadal |
T12768 | 25266-25285 | GO:0008406 | denotes | gonadal development |
T12769 | 25318-25322 | UBERON:0002048 | denotes | lung |
T12770 | 25327-25336 | UBERON:0001103 | denotes | diaphragm |
T12771 | 25383-25392 | UBERON:0002048 | denotes | pulmonary |
T12772 | 25466-25475 | UBERON:0001103 | denotes | diaphragm |
T12773 | 25484-25493 | UBERON:0002048 | denotes | Pulmonary |
T12774 | 25533-25546 | UBERON:0001103 | denotes | diaphragmatic |
T12775 | 25547-25554 | UBERON:0001062 | denotes | anatomy |
T12776 | 25639-25652 | UBERON:0001103 | denotes | diaphragmatic |
T12777 | 25707-25720 | UBERON:0001884 | denotes | phrenic nerve |
T12778 | 25830-25834 | NCBITaxon:9940 | denotes | lamb |
T12779 | 25882-25891 | UBERON:0002048 | denotes | pulmonary |
T12780 | 25882-25905 | GO:0030324 | denotes | pulmonary developmental |
T12781 | 25958-25971 | UBERON:0001103 | denotes | diaphragmatic |
T12782 | 26020-26031 | CHEBI:50905 | denotes | teratogenic |
T12783 | 26159-26164 | UBERON:0009912 | denotes | lobar |
T12784 | 26295-26304 | UBERON:0002048 | denotes | pulmonary |
T12785 | 26334-26338 | NCBITaxon:10088 | denotes | mice |
T12786 | 26361-26365 | PR:000017653 | denotes | Fog2 |
T12787 | 26407-26411 | UBERON:0002048 | denotes | lung |
T12788 | 26407-26423 | GO:0030324 | denotes | lung development |
T12789 | 26471-26475 | UBERON:0009912 | denotes | lobe |
T12790 | 26513-26517 | UBERON:0009912 | denotes | lobe |
T12791 | 26532-26537 | UBERON:0009912 | denotes | lobar |
T12792 | 26570-26574 | PR:000017653 | denotes | Fog2 |
T12793 | 26575-26585 | GO:0010467 | denotes | expression |
T12794 | 26607-26612 | UBERON:0009912 | denotes | lobar |
T12795 | 26628-26632 | PR:000017653 | denotes | Fog2 |
T12796 | 26633-26643 | GO:0010467 | denotes | expression |
T12797 | 26662-26682 | UBERON:0004883 | denotes | pulmonary mesenchyme |
T12798 | 26689-26694 | UBERON:0009912 | denotes | lobar |
T12799 | 26753-26762 | GO:0010467 | denotes | expressed |
T12800 | 26770-26780 | UBERON:0003104 | denotes | mesenchyme |
T12801 | 26810-26814 | UBERON:0009912 | denotes | lobe |
T12802 | 26843-26848 | UBERON:0009912 | denotes | lobes |
T12803 | 26898-26902 | UBERON:0009912 | denotes | lobe |
T12804 | 26917-26921 | UBERON:0009912 | denotes | lobe |
T12805 | 26946-26950 | PR:000017653 | denotes | Fog2 |
T12806 | 27008-27013 | UBERON:0009912 | denotes | lobes |
T12807 | 27048-27052 | PR:000017653 | denotes | Fog2 |
T12808 | 27094-27098 | PR:000017653 | denotes | Fog2 |
T12809 | 27099-27104 | UBERON:0002048 | denotes | lungs |
T12810 | 27196-27200 | PR:000017653 | denotes | Fog2 |
T12811 | 27201-27206 | UBERON:0002048 | denotes | lungs |
T12812 | 27267-27272 | UBERON:0009912 | denotes | lobes |
T12813 | 27322-27327 | UBERON:0002048 | denotes | lungs |
T12814 | 27393-27397 | PR:000017653 | denotes | Fog2 |
T12815 | 27405-27410 | NCBITaxon:10088 | denotes | mouse |
T12816 | 27444-27457 | UBERON:0001103 | denotes | diaphragmatic |
T12817 | 27486-27495 | UBERON:0002048 | denotes | pulmonary |
T12818 | 27559-27563 | SO:0000704 | denotes | gene |
T12819 | 27602-27606 | UBERON:0002048 | denotes | lung |
T12820 | 27602-27606 | _FRAGMENT | denotes | lung |
T12821 | 27621-27632 | GO:0030324 | denotes | development |
T12822 | 27611-27620 | UBERON:0001103 | denotes | diaphragm |
T12823 | 27611-27632 | GO:0060539 | denotes | diaphragm development |
T12824 | 27695-27699 | PR:000017653 | denotes | Fog2 |
T12825 | 27732-27736 | PR:000017653 | denotes | Fog2 |
T12826 | 27747-27752 | NCBITaxon:10088 | denotes | mouse |
T12827 | 27766-27775 | UBERON:0001103 | denotes | diaphragm |
T12828 | 27766-27775 | _FRAGMENT | denotes | diaphragm |
T12829 | 27785-27796 | GO:0060539 | denotes | development |
T12830 | 27780-27784 | UBERON:0002048 | denotes | lung |
T12831 | 27780-27796 | GO:0030324 | denotes | lung development |
T12832 | 28016-28021 | NCBITaxon:9606 | denotes | human |
T14377 | 28325-28332 | SO:0000704 | denotes | Genetic |
T14378 | 28348-28353 | NCBITaxon:10088 | denotes | mouse |
T14379 | 28454-28458 | NCBITaxon:10088 | denotes | mice |
T14380 | 28468-28475 | SO:0000704 | denotes | genetic |
T14381 | 28562-28566 | NCBITaxon:10088 | denotes | Mice |
T14382 | 28595-28599 | PR:000017653 | denotes | Fog2 |
T14383 | 28613-28617 | SO:0000704 | denotes | gene |
T15184 | 28704-28708 | NCBITaxon:10088 | denotes | mice |
T15185 | 28716-28727 | GO:0007565 | denotes | pregnancies |
T15186 | 28770-28777 | UBERON:0000922 | denotes | embryos |
T15187 | 28779-28786 | UBERON:0000922 | denotes | Embryos |
T15188 | 28866-28873 | UBERON:0000922 | denotes | embryos |
T15189 | 28941-28950 | UBERON:0001103 | denotes | diaphragm |
T15190 | 28952-28957 | UBERON:0002048 | denotes | lungs |
T15191 | 28963-28968 | UBERON:0000948 | denotes | heart |
T15192 | 28988-28993 | UBERON:0002048 | denotes | lungs |
T15193 | 28998-29019 | UBERON:0007196 | denotes | tracheobronchial tree |
T15194 | 29052-29062 | UBERON:0001103 | denotes | diaphragms |
T15195 | 29088-29096 | UBERON:0000915 | denotes | thoracic |
T15196 | 29097-29103 | UBERON:0000479 | denotes | tissue |
T15197 | 29125-29132 | UBERON:0000922 | denotes | embryos |
T15198 | 29138-29142 | UBERON:0002048 | denotes | lung |
T15199 | 29160-29165 | UBERON:0002048 | denotes | lungs |
T15200 | 29192-29199 | UBERON:0000922 | denotes | embryos |
T15201 | 29346-29354 | CHEBI:33284 | denotes | nutrient |
T15202 | 29355-29362 | CHEBI:60004 | denotes | mixture |
T15203 | 29454-29460 | NCBITaxon:27592 | denotes | bovine |
T15204 | 29461-29466 | UBERON:0001977 | denotes | serum |
T15205 | 29504-29514 | CHEBI:17334 | denotes | penicillin |
T15206 | 29527-29539 | CHEBI:17076 | denotes | streptomycin |
T15207 | 29557-29571 | CHEBI:2682 | denotes | amphotericin B |
T15208 | 29573-29577 | UBERON:0002048 | denotes | Lung |
T15209 | 29624-29627 | CHEBI:16526 | denotes | CO2 |
T15210 | 29790-29794 | NCBITaxon:10088 | denotes | mice |
T15211 | 29808-29812 | PR:000033987 | denotes | lacZ |
T15212 | 29813-29817 | SO:0000704 | denotes | gene |
T15213 | 29832-29836 | PR:000017653 | denotes | Fog2 |
T15214 | 29837-29845 | SO:0000167 | denotes | promoter |
T15215 | 29891-29898 | NCBITaxon:33208 | denotes | animals |
T15216 | 29904-29908 | PR:000033987 | denotes | lacZ |
T15217 | 29909-29913 | SO:0000704 | denotes | gene |
T15218 | 29954-29958 | PR:000017653 | denotes | Fog2 |
T15219 | 29990-30000 | GO:0010467 | denotes | expression |
T15220 | 30021-30029 | SO:0001817 | denotes | in frame |
T15221 | 30068-30072 | PR:000017653 | denotes | FOG2 |
T15222 | 30086-30090 | PR:000017653 | denotes | Fog2 |
T15223 | 30091-30095 | PR:000033987 | denotes | lacZ |
T15224 | 30121-30125 | SO:0000243 | denotes | ires |
T15225 | 30131-30139 | SO:0005853 | denotes | cassette |
T15226 | 30161-30167 | SO:0001023 | denotes | allele |
T15227 | 30171-30175 | PR:000017653 | denotes | Fog2 |
T15228 | 30176-30180 | SO:0000704 | denotes | gene |
T15229 | 30186-30190 | PR:000017653 | denotes | Fog2 |
T15230 | 30191-30195 | PR:000033987 | denotes | LacZ |
T15231 | 30268-30276 | CL:0002322 | denotes | ES cells |
T15232 | 30377-30388 | UBERON:0000358 | denotes | blastocysts |
T15233 | 30390-30394 | PR:000017653 | denotes | Fog2 |
T15234 | 30395-30399 | PR:000033987 | denotes | lacZ |
T15235 | 30405-30412 | NCBITaxon:33208 | denotes | animals |
T15236 | 30467-30471 | PR:000033987 | denotes | lacZ |
T15237 | 30472-30482 | GO:0010467 | denotes | Expression |
T15238 | 30502-30511 | UBERON:0000922 | denotes | embryonic |
T15239 | 30512-30517 | UBERON:0002048 | denotes | lungs |
T15240 | 30577-30582 | CHEBI:75055 | denotes | X-gal |
T15959 | 30647-30652 | NCBITaxon:10088 | denotes | mouse |
T15960 | 30700-30708 | UBERON:0000915 | denotes | thoracic |
T15961 | 30709-30725 | UBERON:0005291 | denotes | embryonic tissue |
T15962 | 30758-30764 | SO:0000112 | denotes | primer |
T15963 | 30792-30796 | PR:000017653 | denotes | Fog2 |
T15964 | 30797-30801 | SO:0000704 | denotes | gene |
T15965 | 30841-30848 | SO:0000112 | denotes | primers |
T15966 | 30874-30881 | GO:0008380 | denotes | spliced |
T15967 | 30882-30891 | _FRAGMENT | denotes | region of |
T15968 | 30896-30900 | SO:0000842 | denotes | gene |
T15969 | 31009-31020 | SO:0000006 | denotes | PCR product |
T15970 | 31044-31050 | SO:0000440 | denotes | vector |
T15971 | 31147-31151 | SO:0000704 | denotes | gene |
T15972 | 31161-31168 | SO:0000112 | denotes | primers |
T15973 | 31219-31223 | SO:0000704 | denotes | Gene |
T16269 | 31277-31290 | GO:0097617 | denotes | hybridization |
T16270 | 31336-31339 | CHEBI:73702 | denotes | wax |
T16271 | 31393-31406 | GO:0097617 | denotes | hybridization |
T16272 | 31446-31449 | CHEBI:37983 | denotes | 35S |
T16273 | 31503-31510 | SO:0000155 | denotes | plasmid |
T16274 | 31525-31535 | GO:0097617 | denotes | hybridized |
T16275 | 31539-31545 | UBERON:0000479 | denotes | tissue |
T16276 | 31556-31562 | GO:0005634 | denotes | Nuclei |
T16648 | 31670-31675 | NCBITaxon:9606 | denotes | Human |
T16649 | 31755-31761 | CHEBI:15882 | denotes | phenol |
T16650 | 31762-31772 | CHEBI:35255 | denotes | chloroform |
T16651 | 31809-31816 | UBERON:0000479 | denotes | tissues |
T16652 | 31841-31848 | SO:0000112 | denotes | Primers |
T16653 | 31874-31878 | PR:000017653 | denotes | FOG2 |
T16654 | 31879-31891 | SO:0000195 | denotes | coding exons |
T16655 | 31900-31902 | SO:0000028 | denotes | bp |
T16656 | 31906-31914 | SO:0000357 | denotes | flanking |
T16657 | 32018-32024 | SO:0000112 | denotes | Primer |
T16658 | 32112-32116 | SO:0000704 | denotes | Gene |
T16659 | 32194-32199 | UBERON:0000178 | denotes | blood |
T16660 | 32225-32230 | UBERON:0000178 | denotes | blood |
T16661 | 32432-32435 | SO:0000694 | denotes | SNP |
T5124 | 10460-10465 | GO:0007567 | denotes | birth |
R235 | T2478 | T2477 | _lexicallyChainedTo | development,diaphragmatic |
R1800 | T7829 | T7828 | _lexicallyChainedTo | Development,Lung |
R1801 | T7837 | T7836 | _lexicallyChainedTo | development,pulmonary |
R2524 | T9823 | T9822 | _lexicallyChainedTo | liver,left lobe of |
R2996 | T12735 | T12734 | _lexicallyChainedTo | diaphragm,formation of |
R2997 | T12751 | T12750 | _lexicallyChainedTo | differentiation,cell |
R2998 | T12760 | T12759 | _lexicallyChainedTo | 6,Gatas |
R2999 | T12766 | T12765 | _lexicallyChainedTo | development,cardiac |
R3000 | T12821 | T12820 | _lexicallyChainedTo | development,lung |
R3001 | T12829 | T12828 | _lexicallyChainedTo | development,diaphragm |
R4579 | T15968 | T15967 | _lexicallyChainedTo | gene,region of |
R1 | T899 | T898 | _lexicallyChainedTo | Development,Diaphragm |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
16103912-8982563-85559724 | 3242-3243 | 8982563 | denotes | 1 |
16103912-12720181-85559725 | 4013-4014 | 12720181 | denotes | 2 |
16103912-15136994-85559726 | 4015-4016 | 15136994 | denotes | 3 |
16103912-12949279-85559727 | 4189-4190 | 12949279 | denotes | 4 |
16103912-15770591-85559728 | 4525-4526 | 15770591 | denotes | 5 |
16103912-11877660-85559729 | 4527-4528 | 11877660 | denotes | 6 |
16103912-11370980-85559730 | 4608-4609 | 11370980 | denotes | 7 |
16103912-15065021-85559731 | 4895-4896 | 15065021 | denotes | 8 |
16103912-10685274-85559731 | 4895-4896 | 10685274 | denotes | 8 |
16103912-11283873-85559731 | 4895-4896 | 11283873 | denotes | 8 |
16103912-15704183-85559731 | 4895-4896 | 15704183 | denotes | 8 |
16103912-12725592-85559732 | 5495-5497 | 12725592 | denotes | 12 |
16103912-9788565-85559733 | 5498-5500 | 9788565 | denotes | 13 |
16103912-11818962-85559734 | 5926-5928 | 11818962 | denotes | 14 |
16103912-11818962-85559735 | 6987-6989 | 11818962 | denotes | 14 |
16103912-9457677-85559736 | 7275-7277 | 9457677 | denotes | 15 |
16103912-10892744-85559737 | 11526-11528 | 10892744 | denotes | 16 |
16103912-10892744-85559738 | 12179-12181 | 10892744 | denotes | 16 |
16103912-10696067-85559739 | 13459-13461 | 10696067 | denotes | 17 |
16103912-9355800-85559740 | 13462-13464 | 9355800 | denotes | 18 |
16103912-11063939-85559741 | 16654-16656 | 11063939 | denotes | 19 |
16103912-10066685-85559742 | 16657-16659 | 10066685 | denotes | 20 |
16103912-10696067-85559743 | 16781-16783 | 10696067 | denotes | 17 |
16103912-12388344-85559744 | 16784-16786 | 12388344 | denotes | 21 |
16103912-10226008-85559745 | 16787-16789 | 10226008 | denotes | 22 |
16103912-10079225-85559746 | 17013-17015 | 10079225 | denotes | 23 |
16103912-7651534-85559747 | 17159-17161 | 7651534 | denotes | 24 |
16103912-8681797-85559748 | 17162-17164 | 8681797 | denotes | 25 |
16103912-13726619-85559749 | 18930-18932 | 13726619 | denotes | 26 |
16103912-7065526-85559750 | 19651-19653 | 7065526 | denotes | 28 |
16103912-7179186-85559751 | 19764-19766 | 7179186 | denotes | 29 |
16103912-957074-85559752 | 21695-21697 | 957074 | denotes | 30 |
16103912-3783371-85559753 | 21698-21700 | 3783371 | denotes | 31 |
16103912-12692831-85559754 | 21931-21933 | 12692831 | denotes | 32 |
16103912-8724727-85559755 | 22438-22440 | 8724727 | denotes | 33 |
16103912-2809986-85559756 | 22441-22443 | 2809986 | denotes | 34 |
16103912-12725592-85559757 | 22552-22554 | 12725592 | denotes | 12 |
16103912-8982564-85559758 | 22555-22557 | 8982564 | denotes | 35 |
16103912-7815446-85559759 | 22841-22843 | 7815446 | denotes | 36 |
16103912-8953633-85559760 | 22844-22846 | 8953633 | denotes | 37 |
16103912-6601906-85559761 | 22990-22992 | 6601906 | denotes | 38 |
16103912-8896572-85559762 | 23697-23699 | 8896572 | denotes | 41 |
16103912-12508321-85559763 | 24172-24174 | 12508321 | denotes | 42 |
16103912-11090558-85559764 | 24466-24468 | 11090558 | denotes | 43 |
16103912-15659346-85559765 | 25181-25183 | 15659346 | denotes | 44 |
16103912-11382775-85559766 | 25184-25186 | 11382775 | denotes | 45 |
16103912-10696067-85559767 | 25700-25702 | 10696067 | denotes | 17 |
16103912-6894915-85559768 | 25733-25735 | 6894915 | denotes | 46 |
16103912-8982573-85559769 | 25839-25841 | 8982573 | denotes | 48 |
16103912-10751355-85559770 | 26046-26048 | 10751355 | denotes | 49 |
16103912-11076806-85559770 | 26046-26048 | 11076806 | denotes | 49 |
16103912-10646789-85559770 | 26046-26048 | 10646789 | denotes | 49 |
16103912-11083423-85559771 | 26200-26202 | 11083423 | denotes | 52 |
16103912-10892744-85559772 | 28629-28631 | 10892744 | denotes | 16 |
16103912-10948528-85559773 | 31421-31423 | 10948528 | denotes | 53 |
16103912-7516909-85559774 | 31785-31787 | 7516909 | denotes | 54 |
T19249 | 3242-3243 | 8982563 | denotes | 1 |
T63223 | 4013-4014 | 12720181 | denotes | 2 |
T54075 | 4015-4016 | 15136994 | denotes | 3 |
T97796 | 4189-4190 | 12949279 | denotes | 4 |
T1554 | 4525-4526 | 15770591 | denotes | 5 |
T69528 | 4527-4528 | 11877660 | denotes | 6 |
T82541 | 4608-4609 | 11370980 | denotes | 7 |
T46569 | 4895-4896 | 15065021 | denotes | 8 |
T74385 | 4895-4896 | 10685274 | denotes | 8 |
T55607 | 4895-4896 | 11283873 | denotes | 8 |
T71390 | 4895-4896 | 15704183 | denotes | 8 |
T44365 | 5495-5497 | 12725592 | denotes | 12 |
T34234 | 5498-5500 | 9788565 | denotes | 13 |
T84929 | 5926-5928 | 11818962 | denotes | 14 |
T20943 | 6987-6989 | 11818962 | denotes | 14 |
T62259 | 7275-7277 | 9457677 | denotes | 15 |
T65342 | 11526-11528 | 10892744 | denotes | 16 |
T5817 | 12179-12181 | 10892744 | denotes | 16 |
T66232 | 13459-13461 | 10696067 | denotes | 17 |
T74273 | 13462-13464 | 9355800 | denotes | 18 |
T90741 | 16654-16656 | 11063939 | denotes | 19 |
T7030 | 16657-16659 | 10066685 | denotes | 20 |
T63606 | 16781-16783 | 10696067 | denotes | 17 |
T80598 | 16784-16786 | 12388344 | denotes | 21 |
T49937 | 16787-16789 | 10226008 | denotes | 22 |
T83298 | 17013-17015 | 10079225 | denotes | 23 |
T51026 | 17159-17161 | 7651534 | denotes | 24 |
T15263 | 17162-17164 | 8681797 | denotes | 25 |
T38411 | 18930-18932 | 13726619 | denotes | 26 |
T80890 | 19651-19653 | 7065526 | denotes | 28 |
T67813 | 19764-19766 | 7179186 | denotes | 29 |
T12058 | 21695-21697 | 957074 | denotes | 30 |
T42018 | 21698-21700 | 3783371 | denotes | 31 |
T83269 | 21931-21933 | 12692831 | denotes | 32 |
T54695 | 22438-22440 | 8724727 | denotes | 33 |
T9218 | 22441-22443 | 2809986 | denotes | 34 |
T6329 | 22552-22554 | 12725592 | denotes | 12 |
T4249 | 22555-22557 | 8982564 | denotes | 35 |
T59577 | 22841-22843 | 7815446 | denotes | 36 |
T58251 | 22844-22846 | 8953633 | denotes | 37 |
T12323 | 22990-22992 | 6601906 | denotes | 38 |
T40209 | 23697-23699 | 8896572 | denotes | 41 |
T58636 | 24172-24174 | 12508321 | denotes | 42 |
T14097 | 24466-24468 | 11090558 | denotes | 43 |
T16321 | 25181-25183 | 15659346 | denotes | 44 |
T5633 | 25184-25186 | 11382775 | denotes | 45 |
T24984 | 25700-25702 | 10696067 | denotes | 17 |
T85757 | 25733-25735 | 6894915 | denotes | 46 |
T18163 | 25839-25841 | 8982573 | denotes | 48 |
T43074 | 26046-26048 | 10751355 | denotes | 49 |
T39269 | 26046-26048 | 11076806 | denotes | 49 |
T12212 | 26046-26048 | 10646789 | denotes | 49 |
T75735 | 26200-26202 | 11083423 | denotes | 52 |
T59733 | 28629-28631 | 10892744 | denotes | 16 |
T84674 | 31421-31423 | 10948528 | denotes | 53 |
T11695 | 31785-31787 | 7516909 | denotes | 54 |
Biotea
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T474 | 21-27 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78727 | denotes | Normal |
T475 | 1192-1198 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78727 | denotes | normal |
T476 | 21-27 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121439 | denotes | Normal |
T477 | 1192-1198 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121439 | denotes | normal |
T478 | 21-27 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14165 | denotes | Normal |
T479 | 1192-1198 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14165 | denotes | normal |
T480 | 21-27 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48554 | denotes | Normal |
T481 | 1192-1198 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48554 | denotes | normal |
T482 | 21-27 | http://purl.bioontology.org/ontology/SNOMEDCT/17621005 | denotes | Normal |
T483 | 1192-1198 | http://purl.bioontology.org/ontology/SNOMEDCT/17621005 | denotes | normal |
T484 | 28-37 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C23633 | denotes | Diaphragm |
T485 | 1100-1109 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C23633 | denotes | diaphragm |
T486 | 1199-1208 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C23633 | denotes | diaphragm |
T487 | 28-37 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49920 | denotes | Diaphragm |
T488 | 1100-1109 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49920 | denotes | diaphragm |
T489 | 1199-1208 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49920 | denotes | diaphragm |
T490 | 28-37 | http://purl.bioontology.org/ontology/MESH/D003964 | denotes | Diaphragm |
T491 | 1100-1109 | http://purl.bioontology.org/ontology/MESH/D003964 | denotes | diaphragm |
T492 | 1199-1208 | http://purl.bioontology.org/ontology/MESH/D003964 | denotes | diaphragm |
T493 | 28-37 | http://purl.bioontology.org/ontology/OMIM/MTHU001435 | denotes | Diaphragm |
T494 | 1100-1109 | http://purl.bioontology.org/ontology/OMIM/MTHU001435 | denotes | diaphragm |
T495 | 1199-1208 | http://purl.bioontology.org/ontology/OMIM/MTHU001435 | denotes | diaphragm |
T496 | 28-37 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12702 | denotes | Diaphragm |
T497 | 1100-1109 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12702 | denotes | diaphragm |
T498 | 1199-1208 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12702 | denotes | diaphragm |
T499 | 28-37 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C42767 | denotes | Diaphragm |
T500 | 1100-1109 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C42767 | denotes | diaphragm |
T501 | 1199-1208 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C42767 | denotes | diaphragm |
T502 | 28-37 | http://purl.bioontology.org/ontology/MEDDRA/10012704 | denotes | Diaphragm |
T503 | 1100-1109 | http://purl.bioontology.org/ontology/MEDDRA/10012704 | denotes | diaphragm |
T504 | 1199-1208 | http://purl.bioontology.org/ontology/MEDDRA/10012704 | denotes | diaphragm |
T505 | 28-37 | http://purl.bioontology.org/ontology/NDDF/YD | denotes | Diaphragm |
T506 | 1100-1109 | http://purl.bioontology.org/ontology/NDDF/YD | denotes | diaphragm |
T507 | 1199-1208 | http://purl.bioontology.org/ontology/NDDF/YD | denotes | diaphragm |
T508 | 28-37 | http://purl.org/sig/ont/fma/fma13295 | denotes | Diaphragm |
T509 | 1100-1109 | http://purl.org/sig/ont/fma/fma13295 | denotes | diaphragm |
T510 | 1199-1208 | http://purl.org/sig/ont/fma/fma13295 | denotes | diaphragm |
T511 | 28-37 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47890 | denotes | Diaphragm |
T512 | 1100-1109 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47890 | denotes | diaphragm |
T513 | 1199-1208 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47890 | denotes | diaphragm |
T514 | 28-37 | http://purl.bioontology.org/ontology/SNOMEDCT/5798000 | denotes | Diaphragm |
T515 | 1100-1109 | http://purl.bioontology.org/ontology/SNOMEDCT/5798000 | denotes | diaphragm |
T516 | 1199-1208 | http://purl.bioontology.org/ontology/SNOMEDCT/5798000 | denotes | diaphragm |
T517 | 42-58 | http://purl.obolibrary.org/obo/GO_0030324 | denotes | Lung Development |
T518 | 1213-1229 | http://purl.obolibrary.org/obo/GO_0030324 | denotes | lung development |
T519 | 42-58 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19443 | denotes | Lung Development |
T520 | 1213-1229 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19443 | denotes | lung development |
T521 | 42-46 | http://purl.bioontology.org/ontology/MESH/D008168 | denotes | Lung |
T522 | 1213-1217 | http://purl.bioontology.org/ontology/MESH/D008168 | denotes | lung |
T523 | 42-46 | http://purl.bioontology.org/ontology/OMIM/MTHU000106 | denotes | Lung |
T524 | 1213-1217 | http://purl.bioontology.org/ontology/OMIM/MTHU000106 | denotes | lung |
T525 | 42-46 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C23402 | denotes | Lung |
T526 | 1213-1217 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C23402 | denotes | lung |
T527 | 42-46 | http://purl.bioontology.org/ontology/OMIM/MTHU016106 | denotes | Lung |
T528 | 1213-1217 | http://purl.bioontology.org/ontology/OMIM/MTHU016106 | denotes | lung |
T529 | 42-46 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12468 | denotes | Lung |
T530 | 1213-1217 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12468 | denotes | lung |
T531 | 42-46 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | Lung |
T532 | 1213-1217 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T533 | 42-46 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | Lung |
T534 | 1213-1217 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T535 | 42-46 | http://purl.org/sig/ont/fma/fma7195 | denotes | Lung |
T536 | 1213-1217 | http://purl.org/sig/ont/fma/fma7195 | denotes | lung |
T537 | 42-46 | http://purl.bioontology.org/ontology/SNOMEDCT/39607008 | denotes | Lung |
T538 | 1213-1217 | http://purl.bioontology.org/ontology/SNOMEDCT/39607008 | denotes | lung |
T539 | 47-58 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | Development |
T540 | 526-537 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | development |
T541 | 1218-1229 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | development |
T542 | 1422-1433 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | development |
T543 | 47-58 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18732 | denotes | Development |
T544 | 526-537 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18732 | denotes | development |
T545 | 1218-1229 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18732 | denotes | development |
T546 | 1422-1433 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18732 | denotes | development |
T547 | 47-58 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96110 | denotes | Development |
T548 | 526-537 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96110 | denotes | development |
T549 | 1218-1229 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96110 | denotes | development |
T550 | 1422-1433 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96110 | denotes | development |
T551 | 47-58 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17770 | denotes | Development |
T552 | 319-332 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17770 | denotes | developmental |
T553 | 526-537 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17770 | denotes | development |
T554 | 1218-1229 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17770 | denotes | development |
T555 | 1422-1433 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17770 | denotes | development |
T556 | 1542-1555 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17770 | denotes | developmental |
T557 | 47-58 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133991 | denotes | Development |
T558 | 526-537 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133991 | denotes | development |
T559 | 1218-1229 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133991 | denotes | development |
T560 | 1422-1433 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133991 | denotes | development |
T561 | 47-58 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84377 | denotes | Development |
T562 | 526-537 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84377 | denotes | development |
T563 | 1218-1229 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84377 | denotes | development |
T564 | 1422-1433 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84377 | denotes | development |
T565 | 62-66 | http://purl.obolibrary.org/obo/PR_O89094 | denotes | Mice |
T566 | 400-404 | http://purl.obolibrary.org/obo/PR_O89094 | denotes | mice |
T567 | 62-66 | http://purl.obolibrary.org/obo/PR_000005054 | denotes | Mice |
T568 | 400-404 | http://purl.obolibrary.org/obo/PR_000005054 | denotes | mice |
T569 | 62-66 | http://purl.bioontology.org/ontology/MESH/D051379 | denotes | Mice |
T570 | 400-404 | http://purl.bioontology.org/ontology/MESH/D051379 | denotes | mice |
T571 | 62-66 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14238 | denotes | Mice |
T572 | 400-404 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14238 | denotes | mice |
T573 | 71-77 | http://purl.bioontology.org/ontology/MESH/D006801 | denotes | Humans |
T574 | 137-168 | http://purl.bioontology.org/ontology/ICD10/Q79.0 | denotes | Congenital diaphragmatic hernia |
T575 | 1478-1509 | http://purl.bioontology.org/ontology/ICD10/Q79.0 | denotes | congenital diaphragmatic hernia |
T576 | 137-168 | http://purl.bioontology.org/ontology/SNOMEDCT/17190001 | denotes | Congenital diaphragmatic hernia |
T577 | 1478-1509 | http://purl.bioontology.org/ontology/SNOMEDCT/17190001 | denotes | congenital diaphragmatic hernia |
T578 | 137-168 | http://purl.bioontology.org/ontology/OMIM/MTHU018825 | denotes | Congenital diaphragmatic hernia |
T579 | 1478-1509 | http://purl.bioontology.org/ontology/OMIM/MTHU018825 | denotes | congenital diaphragmatic hernia |
T580 | 137-168 | http://purl.bioontology.org/ontology/MEDLINEPLUS/C0235833 | denotes | Congenital diaphragmatic hernia |
T581 | 1478-1509 | http://purl.bioontology.org/ontology/MEDLINEPLUS/C0235833 | denotes | congenital diaphragmatic hernia |
T582 | 137-168 | http://purl.bioontology.org/ontology/MEDDRA/10010439 | denotes | Congenital diaphragmatic hernia |
T583 | 1478-1509 | http://purl.bioontology.org/ontology/MEDDRA/10010439 | denotes | congenital diaphragmatic hernia |
T584 | 137-168 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98893 | denotes | Congenital diaphragmatic hernia |
T585 | 1478-1509 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98893 | denotes | congenital diaphragmatic hernia |
T586 | 137-147 | http://purl.bioontology.org/ontology/SNOMEDCT/255399007 | denotes | Congenital |
T587 | 179-189 | http://purl.bioontology.org/ontology/SNOMEDCT/255399007 | denotes | congenital |
T588 | 1356-1366 | http://purl.bioontology.org/ontology/SNOMEDCT/255399007 | denotes | congenital |
T589 | 1478-1488 | http://purl.bioontology.org/ontology/SNOMEDCT/255399007 | denotes | congenital |
T590 | 137-147 | http://purl.bioontology.org/ontology/MESH/Q000151 | denotes | Congenital |
T591 | 179-189 | http://purl.bioontology.org/ontology/MESH/Q000151 | denotes | congenital |
T592 | 1356-1366 | http://purl.bioontology.org/ontology/MESH/Q000151 | denotes | congenital |
T593 | 1478-1488 | http://purl.bioontology.org/ontology/MESH/Q000151 | denotes | congenital |
T594 | 137-147 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99210 | denotes | Congenital |
T595 | 179-189 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99210 | denotes | congenital |
T596 | 1356-1366 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99210 | denotes | congenital |
T597 | 1478-1488 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99210 | denotes | congenital |
T598 | 148-168 | http://purl.bioontology.org/ontology/ICD10/K44 | denotes | diaphragmatic hernia |
T599 | 1489-1509 | http://purl.bioontology.org/ontology/ICD10/K44 | denotes | diaphragmatic hernia |
T600 | 148-168 | http://purl.bioontology.org/ontology/MEDDRA/10012713 | denotes | diaphragmatic hernia |
T601 | 1489-1509 | http://purl.bioontology.org/ontology/MEDDRA/10012713 | denotes | diaphragmatic hernia |
T602 | 148-168 | http://purl.bioontology.org/ontology/NDFRT/N0000001517 | denotes | diaphragmatic hernia |
T603 | 1489-1509 | http://purl.bioontology.org/ontology/NDFRT/N0000001517 | denotes | diaphragmatic hernia |
T604 | 148-168 | http://purl.bioontology.org/ontology/SNOMEDCT/39839004 | denotes | diaphragmatic hernia |
T605 | 1489-1509 | http://purl.bioontology.org/ontology/SNOMEDCT/39839004 | denotes | diaphragmatic hernia |
T606 | 148-168 | http://purl.bioontology.org/ontology/OMIM/MTHU001436 | denotes | diaphragmatic hernia |
T607 | 1489-1509 | http://purl.bioontology.org/ontology/OMIM/MTHU001436 | denotes | diaphragmatic hernia |
T608 | 148-168 | http://purl.bioontology.org/ontology/MEDLINEPLUS/C0019284 | denotes | diaphragmatic hernia |
T609 | 1489-1509 | http://purl.bioontology.org/ontology/MEDLINEPLUS/C0019284 | denotes | diaphragmatic hernia |
T610 | 148-168 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34687 | denotes | diaphragmatic hernia |
T611 | 1489-1509 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34687 | denotes | diaphragmatic hernia |
T612 | 148-161 | http://purl.bioontology.org/ontology/SNOMEDCT/263734003 | denotes | diaphragmatic |
T613 | 190-203 | http://purl.bioontology.org/ontology/SNOMEDCT/263734003 | denotes | diaphragmatic |
T614 | 512-525 | http://purl.bioontology.org/ontology/SNOMEDCT/263734003 | denotes | diaphragmatic |
T615 | 807-820 | http://purl.bioontology.org/ontology/SNOMEDCT/263734003 | denotes | diaphragmatic |
T616 | 1367-1380 | http://purl.bioontology.org/ontology/SNOMEDCT/263734003 | denotes | diaphragmatic |
T617 | 1489-1502 | http://purl.bioontology.org/ontology/SNOMEDCT/263734003 | denotes | diaphragmatic |
T618 | 162-168 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34685 | denotes | hernia |
T619 | 1503-1509 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34685 | denotes | hernia |
T620 | 162-168 | http://purl.bioontology.org/ontology/OMIM/MTHU012924 | denotes | hernia |
T621 | 1503-1509 | http://purl.bioontology.org/ontology/OMIM/MTHU012924 | denotes | hernia |
T622 | 162-168 | http://purl.bioontology.org/ontology/NDFRT/N0000001516 | denotes | hernia |
T623 | 1503-1509 | http://purl.bioontology.org/ontology/NDFRT/N0000001516 | denotes | hernia |
T624 | 162-168 | http://purl.bioontology.org/ontology/MESH/D006547 | denotes | hernia |
T625 | 1503-1509 | http://purl.bioontology.org/ontology/MESH/D006547 | denotes | hernia |
T626 | 162-168 | http://purl.bioontology.org/ontology/MEDLINEPLUS/C0019270 | denotes | hernia |
T627 | 1503-1509 | http://purl.bioontology.org/ontology/MEDLINEPLUS/C0019270 | denotes | hernia |
T628 | 162-168 | http://purl.bioontology.org/ontology/ICD10/K40-K46.9 | denotes | hernia |
T629 | 1503-1509 | http://purl.bioontology.org/ontology/ICD10/K40-K46.9 | denotes | hernia |
T630 | 162-168 | http://purl.bioontology.org/ontology/SNOMEDCT/414403008 | denotes | hernia |
T631 | 1503-1509 | http://purl.bioontology.org/ontology/SNOMEDCT/414403008 | denotes | hernia |
T632 | 162-168 | http://purl.bioontology.org/ontology/SNOMEDCT/52515009 | denotes | hernia |
T633 | 1503-1509 | http://purl.bioontology.org/ontology/SNOMEDCT/52515009 | denotes | hernia |
T634 | 162-168 | http://purl.bioontology.org/ontology/MEDDRA/10019909 | denotes | hernia |
T635 | 1503-1509 | http://purl.bioontology.org/ontology/MEDDRA/10019909 | denotes | hernia |
T636 | 216-231 | http://purl.bioontology.org/ontology/SNOMEDCT/47429007 | denotes | associated with |
T637 | 216-226 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25281 | denotes | associated |
T638 | 244-253 | http://purl.bioontology.org/ontology/MESH/Q000401 | denotes | mortality |
T639 | 244-253 | http://purl.bioontology.org/ontology/MESH/D009026 | denotes | mortality |
T640 | 244-253 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16880 | denotes | mortality |
T641 | 258-267 | http://purl.bioontology.org/ontology/MESH/D009017 | denotes | morbidity |
T642 | 258-267 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16877 | denotes | morbidity |
T643 | 294-309 | http://purl.bioontology.org/ontology/OMIM/MTHU000008 | denotes | molecular basis |
T644 | 294-303 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25574 | denotes | molecular |
T645 | 304-309 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25430 | denotes | basis |
T646 | 304-309 | http://purl.bioontology.org/ontology/NDFRT/N0000021972 | denotes | basis |
T647 | 319-332 | http://purl.bioontology.org/ontology/SNOMEDCT/278923009 | denotes | developmental |
T648 | 1542-1555 | http://purl.bioontology.org/ontology/SNOMEDCT/278923009 | denotes | developmental |
T649 | 346-353 | http://purl.bioontology.org/ontology/SNOMEDCT/261665006 | denotes | unknown |
T650 | 346-353 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38311 | denotes | unknown |
T651 | 346-353 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150001 | denotes | unknown |
T652 | 346-353 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150002 | denotes | unknown |
T653 | 346-353 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150003 | denotes | unknown |
T654 | 346-353 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C123772 | denotes | unknown |
T655 | 346-353 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998 | denotes | unknown |
T656 | 361-369 | http://purl.bioontology.org/ontology/MESH/Q000032 | denotes | analysis |
T657 | 900-908 | http://purl.bioontology.org/ontology/MESH/Q000032 | denotes | analysis |
T658 | 361-369 | http://purl.bioontology.org/ontology/SNOMEDCT/272389005 | denotes | analysis |
T659 | 900-908 | http://purl.bioontology.org/ontology/SNOMEDCT/272389005 | denotes | analysis |
T660 | 361-369 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25391 | denotes | analysis |
T661 | 900-908 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25391 | denotes | analysis |
T662 | 387-394 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C42885 | denotes | derived |
T663 | 387-394 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73924 | denotes | derived |
T664 | 387-394 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C69271 | denotes | derived |
T665 | 387-394 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81197 | denotes | derived |
T666 | 405-417 | http://purl.bioontology.org/ontology/SNOMEDCT/28995006 | denotes | treated with |
T667 | 405-412 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25705 | denotes | treated |
T668 | 405-412 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C70742 | denotes | treated |
T669 | 418-439 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26563 | denotes | N-ethyl-N-nitrosourea |
T670 | 602-623 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26563 | denotes | N-ethyl-N-nitrosourea |
T671 | 418-439 | http://purl.obolibrary.org/obo/CHEBI_23995 | denotes | N-ethyl-N-nitrosourea |
T672 | 602-623 | http://purl.obolibrary.org/obo/CHEBI_23995 | denotes | N-ethyl-N-nitrosourea |
T673 | 428-439 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C699 | denotes | nitrosourea |
T674 | 612-623 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C699 | denotes | nitrosourea |
T675 | 444-454 | http://purl.bioontology.org/ontology/SNOMEDCT/7882003 | denotes | identified |
T676 | 669-679 | http://purl.bioontology.org/ontology/SNOMEDCT/7882003 | denotes | identified |
T677 | 444-454 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25737 | denotes | identified |
T678 | 669-679 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25737 | denotes | identified |
T679 | 457-465 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16885 | denotes | mutation |
T680 | 632-640 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16885 | denotes | mutation |
T681 | 682-690 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16885 | denotes | mutation |
T682 | 928-936 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16885 | denotes | mutation |
T683 | 457-465 | http://purl.bioontology.org/ontology/MESH/D009154 | denotes | mutation |
T684 | 632-640 | http://purl.bioontology.org/ontology/MESH/D009154 | denotes | mutation |
T685 | 682-690 | http://purl.bioontology.org/ontology/MESH/D009154 | denotes | mutation |
T686 | 872-881 | http://purl.bioontology.org/ontology/MESH/D009154 | denotes | mutations |
T687 | 928-936 | http://purl.bioontology.org/ontology/MESH/D009154 | denotes | mutation |
T688 | 457-465 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45576 | denotes | mutation |
T689 | 632-640 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45576 | denotes | mutation |
T690 | 682-690 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45576 | denotes | mutation |
T691 | 928-936 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45576 | denotes | mutation |
T692 | 478-498 | http://purl.bioontology.org/ontology/OMIM/MTHU004127 | denotes | pulmonary hypoplasia |
T693 | 832-852 | http://purl.bioontology.org/ontology/OMIM/MTHU004127 | denotes | pulmonary hypoplasia |
T694 | 1048-1068 | http://purl.bioontology.org/ontology/OMIM/MTHU004127 | denotes | pulmonary hypoplasia |
T695 | 478-498 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99035 | denotes | pulmonary hypoplasia |
T696 | 832-852 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99035 | denotes | pulmonary hypoplasia |
T697 | 1048-1068 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99035 | denotes | pulmonary hypoplasia |
T698 | 478-498 | http://purl.bioontology.org/ontology/MEDDRA/10037407 | denotes | pulmonary hypoplasia |
T699 | 832-852 | http://purl.bioontology.org/ontology/MEDDRA/10037407 | denotes | pulmonary hypoplasia |
T700 | 1048-1068 | http://purl.bioontology.org/ontology/MEDDRA/10037407 | denotes | pulmonary hypoplasia |
T701 | 478-487 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13304 | denotes | pulmonary |
T702 | 832-841 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13304 | denotes | pulmonary |
T703 | 1048-1057 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13304 | denotes | pulmonary |
T704 | 1412-1421 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13304 | denotes | pulmonary |
T705 | 1532-1541 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13304 | denotes | pulmonary |
T706 | 478-487 | http://purl.bioontology.org/ontology/SNOMEDCT/738985004 | denotes | pulmonary |
T707 | 832-841 | http://purl.bioontology.org/ontology/SNOMEDCT/738985004 | denotes | pulmonary |
T708 | 1048-1057 | http://purl.bioontology.org/ontology/SNOMEDCT/738985004 | denotes | pulmonary |
T709 | 1412-1421 | http://purl.bioontology.org/ontology/SNOMEDCT/738985004 | denotes | pulmonary |
T710 | 1532-1541 | http://purl.bioontology.org/ontology/SNOMEDCT/738985004 | denotes | pulmonary |
T711 | 478-487 | http://purl.bioontology.org/ontology/SNOMEDCT/264164005 | denotes | pulmonary |
T712 | 832-841 | http://purl.bioontology.org/ontology/SNOMEDCT/264164005 | denotes | pulmonary |
T713 | 1048-1057 | http://purl.bioontology.org/ontology/SNOMEDCT/264164005 | denotes | pulmonary |
T714 | 1412-1421 | http://purl.bioontology.org/ontology/SNOMEDCT/264164005 | denotes | pulmonary |
T715 | 1532-1541 | http://purl.bioontology.org/ontology/SNOMEDCT/264164005 | denotes | pulmonary |
T716 | 488-498 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120893 | denotes | hypoplasia |
T717 | 842-852 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120893 | denotes | hypoplasia |
T718 | 1058-1068 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120893 | denotes | hypoplasia |
T719 | 488-498 | http://purl.bioontology.org/ontology/SNOMEDCT/55199003 | denotes | hypoplasia |
T720 | 842-852 | http://purl.bioontology.org/ontology/SNOMEDCT/55199003 | denotes | hypoplasia |
T721 | 1058-1068 | http://purl.bioontology.org/ontology/SNOMEDCT/55199003 | denotes | hypoplasia |
T722 | 503-511 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78802 | denotes | abnormal |
T723 | 732-740 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78802 | denotes | abnormal |
T724 | 503-511 | http://purl.bioontology.org/ontology/SNOMEDCT/263654008 | denotes | abnormal |
T725 | 732-740 | http://purl.bioontology.org/ontology/SNOMEDCT/263654008 | denotes | abnormal |
T726 | 503-511 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25401 | denotes | abnormal |
T727 | 732-740 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25401 | denotes | abnormal |
T728 | 539-543 | http://purl.obolibrary.org/obo/PR_000017653 | denotes | Fog2 |
T729 | 545-550 | http://purl.obolibrary.org/obo/PR_000017653 | denotes | Zfpm2 |
T730 | 664-668 | http://purl.obolibrary.org/obo/PR_000017653 | denotes | Fog2 |
T731 | 885-889 | http://purl.obolibrary.org/obo/PR_000017653 | denotes | FOG2 |
T732 | 1171-1175 | http://purl.obolibrary.org/obo/PR_000017653 | denotes | Fog2 |
T733 | 1280-1284 | http://purl.obolibrary.org/obo/PR_000017653 | denotes | FOG2 |
T734 | 539-543 | http://purl.obolibrary.org/obo/PR_Q8CCH7 | denotes | Fog2 |
T735 | 664-668 | http://purl.obolibrary.org/obo/PR_Q8CCH7 | denotes | Fog2 |
T736 | 885-889 | http://purl.obolibrary.org/obo/PR_Q8CCH7 | denotes | FOG2 |
T737 | 1171-1175 | http://purl.obolibrary.org/obo/PR_Q8CCH7 | denotes | Fog2 |
T738 | 1280-1284 | http://purl.obolibrary.org/obo/PR_Q8CCH7 | denotes | FOG2 |
T739 | 539-543 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102765 | denotes | Fog2 |
T740 | 664-668 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102765 | denotes | Fog2 |
T741 | 885-889 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102765 | denotes | FOG2 |
T742 | 1171-1175 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102765 | denotes | Fog2 |
T743 | 1280-1284 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102765 | denotes | FOG2 |
T744 | 545-550 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102764 | denotes | Zfpm2 |
T745 | 552-556 | http://purl.bioontology.org/ontology/MESH/D019532 | denotes | maps |
T746 | 552-556 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16861 | denotes | maps |
T747 | 568-579 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14353 | denotes | recombinant |
T748 | 580-588 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25543 | denotes | interval |
T749 | 580-588 | http://purl.bioontology.org/ontology/SNOMEDCT/385673002 | denotes | interval |
T750 | 580-588 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48921 | denotes | interval |
T751 | 589-597 | http://purl.bioontology.org/ontology/MESH/D017770 | denotes | carrying |
T752 | 589-597 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81005 | denotes | carrying |
T753 | 624-640 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40987 | denotes | induced mutation |
T754 | 624-640 | http://purl.obolibrary.org/obo/OBI_0001154 | denotes | induced mutation |
T755 | 624-631 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61367 | denotes | induced |
T756 | 624-631 | http://purl.bioontology.org/ontology/SNOMEDCT/16404004 | denotes | induced |
T757 | 646-660 | http://purl.obolibrary.org/obo/OBI_0000626 | denotes | DNA sequencing |
T758 | 646-660 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C153598 | denotes | DNA sequencing |
T759 | 646-649 | http://purl.org/sig/ont/fma/fma74412 | denotes | DNA |
T760 | 646-649 | http://purl.obolibrary.org/obo/GO_0005574 | denotes | DNA |
T761 | 646-649 | http://purl.bioontology.org/ontology/MESH/D004247 | denotes | DNA |
T762 | 646-649 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C135409 | denotes | DNA |
T763 | 646-649 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C449 | denotes | DNA |
T764 | 650-660 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18881 | denotes | sequencing |
T765 | 650-660 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17565 | denotes | sequencing |
T766 | 891-908 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17565 | denotes | Sequence analysis |
T767 | 650-660 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116155 | denotes | sequencing |
T768 | 703-713 | http://purl.bioontology.org/ontology/SNOMEDCT/410609009 | denotes | donor site |
T769 | 703-713 | http://purl.bioontology.org/ontology/SNOMEDCT/410608001 | denotes | donor site |
T770 | 703-708 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25168 | denotes | donor |
T771 | 703-708 | http://purl.obolibrary.org/obo/OBI_1110087 | denotes | donor |
T772 | 703-708 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48284 | denotes | donor |
T773 | 709-713 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13717 | denotes | site |
T774 | 709-713 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37901 | denotes | site |
T775 | 709-713 | http://purl.bioontology.org/ontology/SNOMEDCT/10546003 | denotes | site |
T776 | 709-713 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | site |
T777 | 709-713 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80403 | denotes | site |
T778 | 741-751 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1936 | denotes | transcript |
T779 | 752-760 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80216 | denotes | encoding |
T780 | 773-780 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C64858 | denotes | protein |
T781 | 773-780 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17021 | denotes | protein |
T782 | 773-780 | http://purl.obolibrary.org/obo/GO_0003675 | denotes | protein |
T783 | 773-780 | http://purl.org/sig/ont/fma/fma67257 | denotes | protein |
T784 | 773-780 | http://purl.obolibrary.org/obo/CHEBI_36080 | denotes | protein |
T785 | 773-780 | http://purl.bioontology.org/ontology/NDFRT/N0000148318 | denotes | protein |
T786 | 773-780 | http://purl.obolibrary.org/obo/PR_000000001 | denotes | protein |
T787 | 773-780 | http://purl.obolibrary.org/obo/PR_000000001 | denotes | protein |
T788 | 773-780 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41172 | denotes | protein |
T789 | 773-780 | http://purl.bioontology.org/ontology/SNOMEDCT/88878007 | denotes | protein |
T790 | 773-780 | http://purl.bioontology.org/ontology/MEDDRA/10036987 | denotes | protein |
T791 | 782-787 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14225 | denotes | Human |
T792 | 1350-1355 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14225 | denotes | human |
T793 | 782-787 | http://purl.bioontology.org/ontology/STY/T016 | denotes | Human |
T794 | 1350-1355 | http://purl.bioontology.org/ontology/STY/T016 | denotes | human |
T795 | 782-787 | http://purl.bioontology.org/ontology/STY/T016 | denotes | Human |
T796 | 1350-1355 | http://purl.bioontology.org/ontology/STY/T016 | denotes | human |
T797 | 782-787 | http://purl.bioontology.org/ontology/STY/T016 | denotes | Human |
T798 | 1350-1355 | http://purl.bioontology.org/ontology/STY/T016 | denotes | human |
T799 | 782-787 | http://purl.bioontology.org/ontology/STY/T016 | denotes | Human |
T800 | 1350-1355 | http://purl.bioontology.org/ontology/STY/T016 | denotes | human |
T801 | 782-787 | http://purl.bioontology.org/ontology/STY/T016 | denotes | Human |
T802 | 1350-1355 | http://purl.bioontology.org/ontology/STY/T016 | denotes | human |
T803 | 782-787 | http://purl.bioontology.org/ontology/STY/T016 | denotes | Human |
T804 | 1350-1355 | http://purl.bioontology.org/ontology/STY/T016 | denotes | human |
T805 | 782-787 | http://purl.bioontology.org/ontology/STY/T016 | denotes | Human |
T806 | 1350-1355 | http://purl.bioontology.org/ontology/STY/T016 | denotes | human |
T807 | 782-787 | http://purl.bioontology.org/ontology/STY/T016 | denotes | Human |
T808 | 1350-1355 | http://purl.bioontology.org/ontology/STY/T016 | denotes | human |
T809 | 782-787 | http://purl.bioontology.org/ontology/STY/T016 | denotes | Human |
T810 | 1350-1355 | http://purl.bioontology.org/ontology/STY/T016 | denotes | human |
T811 | 782-787 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
T812 | 1350-1355 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T813 | 782-787 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
T814 | 1350-1355 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T815 | 788-795 | http://purl.bioontology.org/ontology/MESH/D001344 | denotes | autopsy |
T816 | 788-795 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25153 | denotes | autopsy |
T817 | 788-795 | http://purl.bioontology.org/ontology/SNOMEDCT/29240004 | denotes | autopsy |
T818 | 788-795 | http://purl.bioontology.org/ontology/MEDDRA/10050117 | denotes | autopsy |
T819 | 796-801 | http://purl.bioontology.org/ontology/SNOMEDCT/398241000 | denotes | cases |
T820 | 807-827 | http://purl.bioontology.org/ontology/OMIM/MTHU009127 | denotes | diaphragmatic defect |
T821 | 821-827 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43429 | denotes | defect |
T822 | 821-827 | http://purl.bioontology.org/ontology/SNOMEDCT/6920004 | denotes | defect |
T823 | 858-867 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25214 | denotes | evaluated |
T824 | 891-908 | http://purl.bioontology.org/ontology/MESH/D017421 | denotes | Sequence analysis |
T825 | 891-899 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43465 | denotes | Sequence |
T826 | 891-899 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89252 | denotes | Sequence |
T827 | 891-899 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13299 | denotes | Sequence |
T828 | 891-899 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25673 | denotes | Sequence |
T829 | 891-899 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45374 | denotes | Sequence |
T830 | 891-899 | http://purl.obolibrary.org/obo/SO_0000001 | denotes | Sequence |
T831 | 909-917 | http://purl.bioontology.org/ontology/SNOMEDCT/263857004 | denotes | revealed |
T832 | 920-936 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C93106 | denotes | de novo mutation |
T833 | 920-936 | http://purl.bioontology.org/ontology/OMIM/MTHU036578 | denotes | de novo mutation |
T834 | 920-927 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28354 | denotes | de novo |
T835 | 937-949 | http://purl.bioontology.org/ontology/SNOMEDCT/79409006 | denotes | resulting in |
T836 | 952-961 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133441 | denotes | premature |
T838 | 967-972 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62019 | denotes | codon |
T839 | 967-972 | http://purl.bioontology.org/ontology/NDFRT/N0000170695 | denotes | codon |
T840 | 967-972 | http://purl.bioontology.org/ontology/MESH/D003062 | denotes | codon |
T841 | 978-983 | http://purl.bioontology.org/ontology/SNOMEDCT/410601007 | denotes | child |
T842 | 978-983 | http://purl.bioontology.org/ontology/SNOMEDCT/67822003 | denotes | child |
T843 | 978-983 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150886 | denotes | child |
T844 | 978-983 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16423 | denotes | child |
T845 | 978-983 | http://purl.bioontology.org/ontology/MESH/D002648 | denotes | child |
T846 | 978-983 | http://purl.bioontology.org/ontology/NDFRT/N0000010205 | denotes | child |
T847 | 988-992 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28554 | denotes | died |
T848 | 988-992 | http://purl.bioontology.org/ontology/SNOMEDCT/419099009 | denotes | died |
T849 | 1006-1009 | http://purl.bioontology.org/ontology/SNOMEDCT/258703001 | denotes | day |
T850 | 1006-1009 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25301 | denotes | day |
T851 | 1013-1017 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142142 | denotes | life |
T852 | 1013-1017 | http://purl.bioontology.org/ontology/MESH/D019369 | denotes | life |
T853 | 1013-1017 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20203 | denotes | life |
T854 | 1018-1030 | http://purl.bioontology.org/ontology/SNOMEDCT/2603003 | denotes | secondary to |
T855 | 1018-1027 | http://purl.bioontology.org/ontology/SNOMEDCT/2603003 | denotes | secondary |
T856 | 1018-1027 | http://purl.bioontology.org/ontology/MESH/Q000556 | denotes | secondary |
T857 | 1018-1027 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25667 | denotes | secondary |
T858 | 1018-1027 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25666 | denotes | secondary |
T859 | 1031-1037 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C121395 | denotes | severe |
T860 | 1031-1037 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C122951 | denotes | severe |
T861 | 1031-1037 | http://purl.bioontology.org/ontology/SNOMEDCT/24484000 | denotes | severe |
T862 | 1031-1037 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41340 | denotes | severe |
T863 | 1031-1037 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156244 | denotes | severe |
T864 | 1031-1037 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C70667 | denotes | severe |
T865 | 1038-1047 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13332 | denotes | bilateral |
T866 | 1038-1047 | http://purl.bioontology.org/ontology/SNOMEDCT/51440002 | denotes | bilateral |
T867 | 1119-1128 | http://purl.obolibrary.org/obo/OGMS_0000023 | denotes | phenotype |
T868 | 1119-1128 | http://purl.bioontology.org/ontology/SNOMEDCT/8116006 | denotes | phenotype |
T869 | 1119-1128 | http://purl.bioontology.org/ontology/MESH/D010641 | denotes | phenotype |
T870 | 1119-1128 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16977 | denotes | phenotype |
T871 | 1129-1135 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C141290 | denotes | driven |
T872 | 1154-1165 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62559 | denotes | established |
T873 | 1154-1165 | http://purl.bioontology.org/ontology/SNOMEDCT/263748003 | denotes | established |
T874 | 1154-1165 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C71155 | denotes | established |
T875 | 1233-1237 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25199 | denotes | role |
T876 | 1233-1237 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C42754 | denotes | role |
T877 | 1233-1237 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43643 | denotes | role |
T878 | 1233-1237 | http://purl.bioontology.org/ontology/MESH/D012380 | denotes | role |
T879 | 1233-1237 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48835 | denotes | role |
T880 | 1233-1237 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C42768 | denotes | role |
T881 | 1233-1237 | http://purl.obolibrary.org/obo/BFO_0000023 | denotes | role |
T882 | 1233-1237 | http://purl.obolibrary.org/obo/BFO_0000023 | denotes | role |
T883 | 1298-1302 | http://purl.org/sig/ont/fma/fma74402 | denotes | gene |
T884 | 1298-1302 | http://purl.bioontology.org/ontology/SNOMEDCT/67271001 | denotes | gene |
T885 | 1298-1302 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45520 | denotes | gene |
T886 | 1298-1302 | http://purl.obolibrary.org/obo/SO_0000704 | denotes | gene |
T887 | 1298-1302 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 | denotes | gene |
T888 | 1321-1333 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | pathogenesis |
T889 | 1321-1333 | http://purl.bioontology.org/ontology/SNOMEDCT/263547006 | denotes | pathogenesis |
T890 | 1321-1333 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18264 | denotes | pathogenesis |
T891 | 1337-1349 | http://purl.bioontology.org/ontology/OMIM/MTHU021422 | denotes | nonsyndromic |
T892 | 1448-1458 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28362 | denotes | hypothesis |
T893 | 1448-1458 | http://purl.obolibrary.org/obo/OBI_0001908 | denotes | hypothesis |
T894 | 1524-1531 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25251 | denotes | primary |
T895 | 1556-1569 | http://purl.bioontology.org/ontology/MEDLINEPLUS/C0000768 | denotes | abnormalities |
T896 | 1556-1569 | http://purl.bioontology.org/ontology/MESH/Q000002 | denotes | abnormalities |
T466 | 8-16 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25652 | denotes | Required |
T467 | 1179-1187 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25652 | denotes | required |
T468 | 21-27 | http://purl.bioontology.org/ontology/OMIM/MTHU002946 | denotes | Normal |
T469 | 1192-1198 | http://purl.bioontology.org/ontology/OMIM/MTHU002946 | denotes | normal |
T470 | 21-27 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74593 | denotes | Normal |
T471 | 1192-1198 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74593 | denotes | normal |
T472 | 21-27 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140746 | denotes | Normal |
T473 | 1192-1198 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C140746 | denotes | normal |
T837 | 962-972 | http://purl.bioontology.org/ontology/NDFRT/N0000170697 | denotes | stop codon |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T941 | 28-37 | _FRAGMENT | denotes | Diaphragm |
T940 | 28-37 | UBERON:0001103 | denotes | Diaphragm |
T942 | 47-58 | GO:0060539 | denotes | Development |
T943 | 42-46 | UBERON:0002048 | denotes | Lung |
T944 | 42-58 | GO:0030324 | denotes | Lung Development |
T945 | 62-66 | NCBITaxon:10088 | denotes | Mice |
T946 | 71-77 | NCBITaxon:9606 | denotes | Humans |
T947 | 148-161 | UBERON:0001103 | denotes | diaphragmatic |
T948 | 190-203 | UBERON:0001103 | denotes | diaphragmatic |
T949 | 271-279 | PATO_UBERON_EXT:neonate_or_newborn | denotes | neonates |
T950 | 294-303 | CHEBI_EXT:polyatomic_entity_or_group | denotes | molecular |
T951 | 379-386 | UBERON:0000922 | denotes | embryos |
T952 | 400-404 | NCBITaxon:10088 | denotes | mice |
T953 | 418-439 | CHEBI:23995 | denotes | N-ethyl-N-nitrosourea |
T954 | 457-465 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T955 | 478-487 | UBERON:0002048 | denotes | pulmonary |
T956 | 512-525 | UBERON:0001103 | denotes | diaphragmatic |
T957 | 512-537 | GO:0060539 | denotes | diaphragmatic development |
T958 | 539-543 | PR_EXT:000017653 | denotes | Fog2 |
T959 | 545-550 | PR_EXT:000017653 | denotes | Zfpm2 |
T960 | 568-579 | GO_SO_EXT:sequence_rearrangement_process | denotes | recombinant |
T961 | 602-623 | CHEBI:23995 | denotes | N-ethyl-N-nitrosourea |
T962 | 632-640 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T963 | 646-649 | CHEBI_SO_EXT:DNA | denotes | DNA |
T964 | 664-668 | PR_EXT:000017653 | denotes | Fog2 |
T965 | 682-690 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T966 | 696-702 | GO:0008380 | denotes | splice |
T967 | 696-713 | SO_EXT:splice_donor | denotes | splice donor site |
T968 | 741-751 | SO_EXT:0000673 | denotes | transcript |
T969 | 752-760 | SO_EXT:sequence_coding_function | denotes | encoding |
T970 | 763-772 | SO_EXT:sequence_truncation_process | denotes | truncated |
T971 | 773-780 | CHEBI_PR_EXT:protein | denotes | protein |
T972 | 782-787 | NCBITaxon:9606 | denotes | Human |
T973 | 807-820 | UBERON:0001103 | denotes | diaphragmatic |
T974 | 832-841 | UBERON:0002048 | denotes | pulmonary |
T975 | 872-881 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutations |
T976 | 885-889 | PR_EXT:000017653 | denotes | FOG2 |
T977 | 891-899 | SO_EXT:biological_sequence | denotes | Sequence |
T978 | 928-936 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T979 | 952-972 | SO_EXT:0001587 | denotes | premature stop codon |
T980 | 978-983 | NCBITaxon_UBERON_EXT:child | denotes | child |
T981 | 988-992 | GO:0016265 | denotes | died |
T982 | 1013-1017 | UBERON:0000104 | denotes | life |
T983 | 1048-1057 | UBERON:0002048 | denotes | pulmonary |
T984 | 1087-1099 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularized |
T985 | 1100-1109 | UBERON:0001103 | denotes | diaphragm |
T986 | 1171-1175 | PR_EXT:000017653 | denotes | Fog2 |
T987 | 1199-1208 | UBERON:0001103 | denotes | diaphragm |
T988 | 1213-1217 | UBERON:0002048 | denotes | lung |
T989 | 1213-1229 | GO:0030324 | denotes | lung development |
T990 | 1280-1284 | PR_EXT:000017653 | denotes | FOG2 |
T991 | 1298-1302 | SO_EXT:0000704 | denotes | gene |
T992 | 1350-1355 | NCBITaxon:9606 | denotes | human |
T993 | 1367-1380 | UBERON:0001103 | denotes | diaphragmatic |
T994 | 1412-1421 | UBERON:0002048 | denotes | pulmonary |
T995 | 1412-1433 | GO:0030324 | denotes | pulmonary development |
T996 | 1464-1472 | PATO_UBERON_EXT:neonate_or_newborn | denotes | neonates |
T997 | 1489-1502 | UBERON:0001103 | denotes | diaphragmatic |
T998 | 1532-1541 | UBERON:0002048 | denotes | pulmonary |
T999 | 1532-1555 | GO:0030324 | denotes | pulmonary developmental |
T2495 | 3038-3051 | UBERON:0001103 | denotes | diaphragmatic |
T2497 | 3184-3197 | UBERON:0001103 | denotes | diaphragmatic |
T2498 | 3293-3306 | UBERON:0001103 | denotes | diaphragmatic |
T2499 | 3328-3333 | GO:0007567 | denotes | birth |
T2500 | 3335-3348 | UBERON:0001103 | denotes | diaphragmatic |
T2501 | 3361-3374 | UBERON:0001103 | denotes | diaphragmatic |
T2502 | 3375-3390 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T2503 | 3472-3480 | UBERON:0001062 | denotes | anatomic |
T2504 | 3584-3590 | GO:0016265 | denotes | mortem |
T2505 | 3605-3614 | UBERON:0002048 | denotes | Pulmonary |
T2506 | 3648-3661 | UBERON:0001103 | denotes | diaphragmatic |
T2507 | 3765-3778 | UBERON:0001103 | denotes | diaphragmatic |
T2508 | 3791-3800 | UBERON:0002048 | denotes | pulmonary |
T2509 | 3878-3887 | UBERON:0002048 | denotes | pulmonary |
T2510 | 4123-4129 | GO:0016265 | denotes | deaths |
T2511 | 4139-4144 | GO:0007567 | denotes | birth |
T2512 | 4151-4159 | GO_EXT:biological_movement_or_translocation_process | denotes | transfer |
T2513 | 4240-4251 | UBERON:0001004 | denotes | respiratory |
T2514 | 4263-4268 | GO:0007567 | denotes | birth |
T2515 | 4388-4392 | UBERON:0002048 | denotes | lung |
T2516 | 4406-4415 | UBERON_EXT:body | denotes | corporeal |
T2517 | 4425-4436 | GO:0015671 | denotes | oxygenation |
T2518 | 4501-4516 | UBERON_EXT:heart_or_lung | denotes | cardiopulmonary |
T2519 | 4695-4706 | UBERON:0001004 | denotes | respiratory |
T2520 | 4722-4731 | GO:0050890 | denotes | cognitive |
T2521 | 4736-4746 | GO:0050905 | denotes | neuromotor |
T2522 | 4761-4768 | GO:0007605 | denotes | hearing |
T2523 | 4939-4948 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutations |
T2524 | 4990-5003 | UBERON:0001103 | denotes | diaphragmatic |
T2525 | 5016-5025 | UBERON:0002048 | denotes | pulmonary |
T2526 | 5040-5046 | NCBITaxon:9606 | denotes | humans |
T2527 | 5199-5206 | SO_EXT:0000704 | denotes | genetic |
T2528 | 5277-5286 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutations |
T2529 | 5311-5320 | CHEBI_EXT:polyatomic_entity_or_group | denotes | molecular |
T2530 | 5357-5370 | UBERON:0001103 | denotes | diaphragmatic |
T2531 | 5357-5382 | GO:0060539 | denotes | diaphragmatic development |
T2532 | 5441-5452 | GO_SO_EXT:chromosome | denotes | chromosomal |
T2533 | 5536-5542 | GO_EXT:fatality_or_lethality | denotes | lethal |
T2534 | 5574-5580 | NCBITaxon:9606 | denotes | humans |
T2535 | 5626-5632 | NCBITaxon:33208 | denotes | animal |
T2536 | 5643-5648 | NCBITaxon:9606 | denotes | human |
T2537 | 5649-5654 | GO:0007567 | denotes | birth |
T2538 | 5680-5687 | SO_EXT:0000704 | denotes | genetic |
T2539 | 5711-5717 | NCBITaxon:33208 | denotes | animal |
T2540 | 5753-5758 | NCBITaxon:9606 | denotes | human |
T2541 | 5784-5788 | NCBITaxon:10088 | denotes | mice |
T2542 | 5806-5814 | CHEBI_EXT:chemical_substance_or_polyatomic_entity | denotes | chemical |
T2543 | 5815-5822 | CHEBI_EXT:25435 | denotes | mutagen |
T2544 | 5823-5844 | CHEBI:23995 | denotes | N-ethyl-N-nitrosourea |
T2545 | 5846-5849 | CHEBI:23995 | denotes | ENU |
T2546 | 5908-5924 | UBERON:0012101 | denotes | perinatal period |
T2547 | 5912-5917 | GO:0007567 | denotes | natal |
T2548 | 5973-5977 | NCBITaxon:10088 | denotes | mice |
T2549 | 5999-6007 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T2550 | 6032-6041 | UBERON:0002048 | denotes | pulmonary |
T2551 | 6066-6079 | UBERON:0001103 | denotes | diaphragmatic |
T2552 | 6066-6079 | _FRAGMENT | denotes | diaphragmatic |
T2553 | 6092-6103 | GO:0060539 | denotes | development |
T2554 | 6084-6091 | UBERON:0000948 | denotes | cardiac |
T2555 | 6084-6103 | GO:0007507 | denotes | cardiac development |
T2556 | 6116-6123 | SO_EXT:sequence_cloning_process | denotes | cloning |
T2557 | 6144-6148 | PR_EXT:000017653 | denotes | Fog2 |
T2558 | 6150-6155 | PR_EXT:000017653 | denotes | Zfpm2 |
T2559 | 6184-6187 | CHEBI_SO_EXT:DNA | denotes | DNA |
T2560 | 6210-6218 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T2561 | 6224-6230 | GO:0008380 | denotes | splice |
T2562 | 6224-6241 | SO_EXT:splice_donor | denotes | splice donor site |
T2563 | 6269-6279 | SO_EXT:0000673 | denotes | transcript |
T2564 | 6280-6288 | SO_EXT:sequence_coding_function | denotes | encoding |
T2565 | 6291-6300 | SO_EXT:sequence_truncation_process | denotes | truncated |
T2566 | 6301-6308 | CHEBI_PR_EXT:protein | denotes | protein |
T2567 | 6352-6363 | SO:0000858 | denotes | orthologous |
T2568 | 6364-6368 | SO_EXT:0000704 | denotes | gene |
T2569 | 6372-6378 | NCBITaxon:9606 | denotes | humans |
T2570 | 6454-6462 | SO_EXT:nonsense_quality_or_entity | denotes | nonsense |
T2571 | 6463-6471 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T2572 | 6475-6479 | PR_EXT:000017653 | denotes | FOG2 |
T2573 | 6497-6501 | GO:0016265 | denotes | died |
T2574 | 6505-6510 | GO:0007567 | denotes | birth |
T2575 | 6518-6531 | UBERON:0001103 | denotes | diaphragmatic |
T2576 | 6550-6559 | UBERON:0002048 | denotes | pulmonary |
T2577 | 6599-6607 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T2578 | 6649-6654 | NCBITaxon:9606 | denotes | human |
T2579 | 6717-6726 | UBERON:0002048 | denotes | pulmonary |
T5179 | 6835-6839 | UBERON:0002048 | denotes | lung |
T5180 | 6840-6848 | SO_EXT:sequence_alteration_entity_or_process | denotes | Mutation |
T5181 | 6852-6856 | PR_EXT:000017653 | denotes | Fog2 |
T5182 | 6897-6900 | CHEBI:23995 | denotes | ENU |
T5183 | 6913-6917 | NCBITaxon:10088 | denotes | mice |
T5184 | 6921-6930 | UBERON:0000922 | denotes | embryonic |
T5185 | 7004-7008 | NCBITaxon:10088 | denotes | mice |
T5186 | 7036-7043 | UBERON:0000922 | denotes | embryos |
T5187 | 7082-7091 | UBERON:0002048 | denotes | pulmonary |
T5188 | 7114-7123 | UBERON:0001103 | denotes | diaphragm |
T5189 | 7129-7137 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T5190 | 7162-7166 | UBERON:0002048 | denotes | lung |
T5191 | 7188-7198 | GO_SO_EXT:chromosome | denotes | Chromosome |
T5192 | 7238-7247 | SO_EXT:0001024 | denotes | haplotype |
T5193 | 7408-7409 | SO_EXT:normal_or_wild_type_or_present | denotes | + |
T5194 | 7410-7414 | NCBITaxon:10088 | denotes | mice |
T5195 | 7444-7452 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T5196 | 7471-7483 | SO_EXT:sequence_recombinant_entity | denotes | recombinants |
T5197 | 7552-7559 | CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag | denotes | markers |
T5198 | 7678-7690 | SO_EXT:sequence_recombinant_entity | denotes | recombinants |
T5199 | 7754-7762 | SO:0000357 | denotes | flanking |
T5200 | 7763-7770 | CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag | denotes | markers |
T5201 | 7832-7841 | UBERON:0002048 | denotes | pulmonary |
T5202 | 7869-7878 | UBERON:0001103 | denotes | diaphragm |
T5203 | 7880-7889 | UBERON:0002048 | denotes | Pulmonary |
T5204 | 7921-7927 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5205 | 7928-7932 | NCBITaxon:10088 | denotes | mice |
T5206 | 7950-7955 | GO:0007567 | denotes | birth |
T5207 | 7981-7990 | SO_EXT:wild_type_entity_or_quality | denotes | wild-type |
T5208 | 7995-8001 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5209 | 8002-8006 | NCBITaxon:10088 | denotes | mice |
T5210 | 8032-8036 | UBERON:0000104 | denotes | life |
T5211 | 8038-8042 | UBERON_EXT:body | denotes | body |
T5212 | 8084-8088 | UBERON:0002048 | denotes | lung |
T5213 | 8129-8135 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5214 | 8136-8140 | NCBITaxon:10088 | denotes | mice |
T5215 | 8154-8160 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5216 | 8161-8165 | UBERON:0002048 | denotes | lung |
T5217 | 8208-8217 | SO_EXT:wild_type_entity_or_quality | denotes | wild-type |
T5218 | 8218-8222 | UBERON:0002048 | denotes | lung |
T5219 | 8265-8270 | UBERON:0002048 | denotes | lungs |
T5220 | 8276-8282 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5221 | 8283-8287 | NCBITaxon:10088 | denotes | mice |
T5222 | 8314-8318 | UBERON:0009912 | denotes | lobe |
T5223 | 8391-8395 | UBERON:0009912 | denotes | lobe |
T5224 | 8409-8419 | UBERON:0001103 | denotes | Diaphragms |
T5225 | 8425-8431 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5226 | 8436-8440 | NCBITaxon:10088 | denotes | mice |
T5227 | 8458-8473 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T5228 | 8508-8518 | CL:0002372 | denotes | Myotubules |
T5229 | 8591-8601 | CL:0002372 | denotes | myotubules |
T5230 | 8665-8675 | UBERON:0000309 | denotes | body walls |
T5231 | 8702-8708 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscle |
T5232 | 8702-8715 | CL:0000187 | denotes | muscle fibers |
T5233 | 8723-8740 | UBERON:0006670 | denotes | central tendonous |
T5234 | 8756-8762 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5235 | 8763-8772 | UBERON:0001103 | denotes | diaphragm |
T5236 | 8774-8784 | CL:0002372 | denotes | myotubules |
T5237 | 8831-8844 | UBERON:0002385 | denotes | muscle tissue |
T5238 | 8884-8894 | UBERON:0000309 | denotes | body walls |
T5239 | 9382-9388 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5240 | 9389-9393 | NCBITaxon:10088 | denotes | mice |
T5241 | 9411-9416 | GO:0007567 | denotes | birth |
T5242 | 9497-9505 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T5243 | 9541-9550 | UBERON:0000922 | denotes | embryonic |
T5244 | 9620-9627 | UBERON:0000995 | denotes | uterine |
T5245 | 9628-9634 | GO:0016265 | denotes | demise |
T5246 | 9701-9708 | UBERON:0000922 | denotes | embryos |
T5247 | 9760-9767 | UBERON:0000995 | denotes | uterine |
T5248 | 9768-9774 | GO:0016265 | denotes | demise |
T5249 | 9786-9792 | GO_EXT:biological_growth_entity_or_process | denotes | growth |
T5250 | 9818-9824 | UBERON:0000479 | denotes | tissue |
T5251 | 9841-9848 | UBERON:0000922 | denotes | embryos |
T5252 | 9884-9890 | GO:0016265 | denotes | demise |
T5253 | 9969-9977 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T5254 | 10043-10049 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5255 | 10062-10066 | GO:0016265 | denotes | died |
T5256 | 10102-10108 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5257 | 10129-10135 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5258 | 10136-10143 | UBERON:0000922 | denotes | embryos |
T5259 | 10167-10171 | GO:0016265 | denotes | died |
T5260 | 10194-10201 | UBERON:0000922 | denotes | embryos |
T5261 | 10232-10240 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T5262 | 10260-10266 | UBERON:0000922 | denotes | embryo |
T5263 | 10279-10292 | UBERON:0001103 | denotes | Diaphragmatic |
T5264 | 10293-10308 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T5265 | 10329-10335 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5266 | 10336-10340 | NCBITaxon:10088 | denotes | mice |
T5267 | 10360-10369 | UBERON:0002048 | denotes | Pulmonary |
T5268 | 10405-10412 | SO_EXT:sequence_altered_entity | denotes | mutants |
T5269 | 10460-10465 | GO:0007567 | denotes | birth |
T5270 | 10491-10498 | UBERON:0000948 | denotes | cardiac |
T5271 | 10522-10528 | UBERON:0000948 | denotes | hearts |
T5272 | 10544-10550 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5273 | 10551-10555 | NCBITaxon:10088 | denotes | mice |
T5274 | 10640-10660 | UBERON:0002062 | denotes | endocardial cushions |
T5275 | 10671-10677 | UBERON:0004145 | denotes | outlet |
T5276 | 10678-10693 | UBERON:0002080 | denotes | right ventricle |
T5277 | 10710-10732 | UBERON:0002087 | denotes | atrioventricular canal |
T5278 | 10738-10748 | UBERON:0002349 | denotes | myocardium |
T5279 | 10803-10816 | UBERON:0004125 | denotes | compact layer |
T5280 | 10858-10864 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5281 | 10865-10869 | NCBITaxon:10088 | denotes | mice |
T5282 | 10887-10892 | GO:0007567 | denotes | birth |
T5283 | 10902-10909 | UBERON:0000948 | denotes | cardiac |
T5284 | 10934-10956 | UBERON:0002087 | denotes | atrioventricular-canal |
T5285 | 10962-10980 | UBERON:0002094 | denotes | ventricular septal |
T5286 | 10990-11003 | UBERON:0009149 | denotes | ostium primum |
T5287 | 11004-11017 | UBERON:0002085 | denotes | atrial septal |
T5288 | 11040-11045 | UBERON:0002081 | denotes | atria |
T5289 | 11068-11075 | SO_EXT:sequence_altered_entity | denotes | mutants |
T5290 | 11105-11112 | UBERON:0000948 | denotes | cardiac |
T5291 | 11145-11152 | UBERON:0000948 | denotes | cardiac |
T5292 | 11145-11164 | GO:0007507 | denotes | cardiac development |
T5293 | 11188-11189 | CHEBI_SO_EXT:base | denotes | b |
T5294 | 11229-11232 | CHEBI_SO_EXT:DNA | denotes | DNA |
T5295 | 11233-11241 | SO_EXT:biological_sequence | denotes | sequence |
T5296 | 11267-11282 | SO_EXT:0000996 | denotes | predicted genes |
T5297 | 11298-11303 | SO_EXT:0000704 | denotes | genes |
T5298 | 11315-11319 | PR_EXT:000017653 | denotes | Fog2 |
T5299 | 11330-11339 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutations |
T5300 | 11343-11347 | PR_EXT:000017653 | denotes | Fog2 |
T5301 | 11353-11360 | UBERON:0000948 | denotes | cardiac |
T5302 | 11418-11424 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5303 | 11425-11429 | NCBITaxon:10088 | denotes | mice |
T5304 | 11441-11463 | UBERON:0002087 | denotes | atrioventricular canal |
T5305 | 11481-11491 | UBERON:0002349 | denotes | myocardium |
T5306 | 11504-11512 | UBERON:0005985 | denotes | coronary |
T5307 | 11513-11524 | UBERON:0002049 | denotes | vasculature |
T5308 | 11531-11533 | GO_EXT:reverse_transcription_or_reverse_transcriptase | denotes | RT |
T5309 | 11579-11583 | PR_EXT:000017653 | denotes | Fog2 |
T5310 | 11600-11611 | SO_EXT:0000673 | denotes | transcripts |
T5311 | 11623-11629 | SO_EXT:sequence_altered_entity | denotes | mutant |
T5312 | 11642-11651 | SO_EXT:wild_type_entity_or_quality | denotes | wild-type |
T5313 | 11652-11659 | UBERON:0000922 | denotes | embryos |
T5314 | 11691-11697 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5315 | 11698-11708 | SO_EXT:0000673 | denotes | transcript |
T5316 | 11720-11734 | SO_EXT:point_mutation_entity_or_process | denotes | point mutation |
T5317 | 11741-11748 | CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | thymine |
T5318 | 11752-11760 | CHEBI_EXT:cytosine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | cytosine |
T5319 | 11764-11766 | SO_EXT:0000028 | denotes | bp |
T5320 | 11803-11809 | GO:0008380 | denotes | splice |
T5321 | 11803-11820 | SO_EXT:splice_donor | denotes | splice donor site |
T5322 | 11845-11849 | SO_EXT:0000147 | denotes | exon |
T5323 | 11856-11864 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T5324 | 11874-11882 | GO:0008380 | denotes | splicing |
T5325 | 11910-11919 | SO_EXT:sequence_insertion_entity_or_process | denotes | insertion |
T5326 | 11926-11928 | SO_EXT:0000028 | denotes | bp |
T5327 | 11932-11940 | SO_EXT:0000188 | denotes | intronic |
T5328 | 11941-11949 | SO_EXT:biological_sequence | denotes | sequence |
T5329 | 11959-11965 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5330 | 11966-11976 | SO_EXT:0000673 | denotes | transcript |
T5331 | 11995-12005 | SO_EXT:0000319 | denotes | stop codon |
T5332 | 12032-12041 | SO_EXT:sequence_truncation_process | denotes | truncated |
T5333 | 12042-12049 | CHEBI_PR_EXT:protein | denotes | protein |
T5334 | 12088-12094 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T5335 | 12095-12099 | NCBITaxon:10088 | denotes | mice |
T5336 | 12120-12124 | PR_EXT:000017653 | denotes | Fog2 |
T5337 | 12125-12126 | SO_EXT:normal_or_wild_type_or_present | denotes | + |
T5338 | 12127-12128 | SO_EXT:sequence_nullness_or_absence | denotes | − |
T5339 | 12130-12134 | SO_EXT:sequence_nullness | denotes | null |
T5340 | 12135-12141 | SO_EXT:0001023 | denotes | allele |
T5341 | 12143-12149 | SO_EXT:sequence_altered_entity | denotes | mutant |
T5342 | 12163-12167 | SO_EXT:0000704 | denotes | gene |
T5343 | 12204-12208 | NCBITaxon:10088 | denotes | mice |
T5344 | 12216-12225 | UBERON:0000922 | denotes | embryonic |
T5345 | 12226-12232 | GO_EXT:fatality_or_lethality | denotes | lethal |
T5346 | 12292-12300 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T5347 | 12304-12308 | PR_EXT:000017653 | denotes | Fog2 |
T5348 | 12340-12344 | NCBITaxon:10088 | denotes | mice |
T5349 | 12377-12381 | PR_EXT:000017653 | denotes | Fog2 |
T5350 | 12382-12386 | SO_EXT:sequence_nullness | denotes | null |
T5351 | 12387-12393 | SO_EXT:sequence_altered_entity | denotes | mutant |
T5352 | 12452-12462 | SO_EXT:0000673 | denotes | transcript |
T5353 | 12491-12497 | GO:0008380 | denotes | splice |
T5354 | 12491-12502 | SO_EXT:0000162 | denotes | splice site |
T5355 | 12503-12511 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T7954 | 12938-12942 | UBERON:0002048 | denotes | Lung |
T7955 | 12938-12942 | _FRAGMENT | denotes | Lung |
T7956 | 12957-12968 | GO:0030324 | denotes | Development |
T7957 | 12947-12956 | UBERON:0001103 | denotes | Diaphragm |
T7958 | 12947-12968 | GO:0060539 | denotes | Diaphragm Development |
T7959 | 12976-12980 | PR_EXT:000017653 | denotes | Fog2 |
T7960 | 12981-12987 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | Mutant |
T7961 | 12988-12993 | NCBITaxon:10088 | denotes | Mouse |
T7962 | 13045-13049 | PR_EXT:000017653 | denotes | Fog2 |
T7963 | 13053-13062 | UBERON:0002048 | denotes | pulmonary |
T7964 | 13053-13062 | _FRAGMENT | denotes | pulmonary |
T7965 | 13081-13092 | GO:0030324 | denotes | development |
T7966 | 13067-13080 | UBERON:0001103 | denotes | diaphragmatic |
T7967 | 13067-13092 | GO:0060539 | denotes | diaphragmatic development |
T7968 | 13098-13107 | UBERON:0002048 | denotes | pulmonary |
T7969 | 13192-13196 | UBERON:0009912 | denotes | lobe |
T7970 | 13231-13235 | UBERON:0009912 | denotes | lobe |
T7971 | 13289-13302 | UBERON:0001103 | denotes | diaphragmatic |
T7972 | 13289-13314 | GO:0060539 | denotes | diaphragmatic development |
T7973 | 13360-13369 | UBERON:0002048 | denotes | pulmonary |
T7974 | 13467-13471 | PR_EXT:000017653 | denotes | Fog2 |
T7975 | 13475-13484 | GO:0010467 | denotes | expressed |
T7976 | 13502-13522 | UBERON:0004883 | denotes | pulmonary mesenchyme |
T7977 | 13544-13567 | GO:0001763 | denotes | branching morphogenesis |
T7978 | 13581-13591 | GO:0010467 | denotes | expression |
T7979 | 13613-13627 | UBERON:0001135 | denotes | smooth muscles |
T7980 | 13631-13638 | UBERON:0001005 | denotes | airways |
T7981 | 13643-13652 | UBERON:0002048 | denotes | pulmonary |
T7982 | 13653-13660 | UBERON:0000055 | denotes | vessels |
T7983 | 13704-13709 | UBERON:0002048 | denotes | lungs |
T7984 | 13767-13780 | UBERON:0001103 | denotes | diaphragmatic |
T7985 | 13781-13796 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T7986 | 13828-13837 | UBERON:0002048 | denotes | pulmonary |
T7987 | 13877-13890 | UBERON:0001103 | denotes | diaphragmatic |
T7988 | 13924-13929 | UBERON:0002048 | denotes | lungs |
T7989 | 13950-13954 | PR_EXT:000017653 | denotes | Fog2 |
T7990 | 13955-13956 | SO_EXT:sequence_nullness_or_absence | denotes | − |
T7991 | 13957-13958 | SO_EXT:sequence_nullness_or_absence | denotes | − |
T7992 | 13959-13963 | NCBITaxon:10088 | denotes | mice |
T7993 | 14014-14027 | UBERON:0001103 | denotes | diaphragmatic |
T7994 | 14028-14034 | GO_EXT:biological_movement_or_translocation_process | denotes | motion |
T7995 | 14036-14040 | PR_EXT:000017653 | denotes | Fog2 |
T7996 | 14041-14042 | SO_EXT:sequence_nullness_or_absence | denotes | − |
T7997 | 14043-14044 | SO_EXT:sequence_nullness_or_absence | denotes | − |
T7998 | 14045-14049 | NCBITaxon:10088 | denotes | mice |
T7999 | 14158-14166 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T8000 | 14168-14173 | UBERON:0002048 | denotes | Lungs |
T8001 | 14196-14200 | PR_EXT:000017653 | denotes | Fog2 |
T8002 | 14201-14202 | SO_EXT:sequence_nullness_or_absence | denotes | − |
T8003 | 14203-14204 | SO_EXT:sequence_nullness_or_absence | denotes | − |
T8004 | 14205-14212 | UBERON:0000922 | denotes | embryos |
T8005 | 14277-14281 | UBERON:0009912 | denotes | lobe |
T8006 | 14296-14300 | PR_EXT:000017653 | denotes | Fog2 |
T8007 | 14300-14301 | SO_EXT:sequence_nullness_or_absence | denotes | − |
T8008 | 14303-14304 | SO_EXT:sequence_nullness_or_absence | denotes | − |
T8010 | 14372-14376 | UBERON:0009912 | denotes | lobe |
T8011 | 14397-14403 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T8012 | 14404-14409 | UBERON:0002048 | denotes | lungs |
T8013 | 14530-14539 | UBERON:0002048 | denotes | pulmonary |
T8014 | 14554-14558 | PR_EXT:000017653 | denotes | Fog2 |
T8015 | 14559-14565 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T8016 | 14566-14570 | NCBITaxon:10088 | denotes | mice |
T8017 | 15232-15237 | UBERON:0009912 | denotes | lobes |
T8018 | 15280-15287 | SO_EXT:sequence_altered_entity | denotes | mutants |
T8019 | 15347-15352 | UBERON:0009912 | denotes | lobes |
T8020 | 15388-15392 | PR_EXT:000017653 | denotes | Fog2 |
T8021 | 15428-15433 | UBERON:0009912 | denotes | lobar |
T8022 | 15463-15467 | PR_EXT:000017653 | denotes | Fog2 |
T8023 | 15468-15478 | GO:0010467 | denotes | expression |
T8024 | 15503-15510 | UBERON:0000922 | denotes | embryos |
T8025 | 15538-15543 | UBERON:0009912 | denotes | lobar |
T8026 | 15579-15583 | PR_EXT:000017653 | denotes | Fog2 |
T8027 | 15584-15594 | GO:0010467 | denotes | expression |
T8028 | 15630-15635 | UBERON:0009912 | denotes | lobar |
T8029 | 15642-15652 | GO:0010467 | denotes | Expression |
T8030 | 15670-15674 | NCBITaxon:10088 | denotes | mice |
T8031 | 15686-15690 | PR_EXT:000033987 | denotes | lacZ |
T8032 | 15691-15695 | SO_EXT:0000704 | denotes | gene |
T8033 | 15718-15722 | PR_EXT:000017653 | denotes | Fog2 |
T8034 | 15770-15774 | NCBITaxon:10088 | denotes | mice |
T8035 | 15798-15803 | UBERON:0002048 | denotes | lungs |
T8036 | 15837-15841 | PR_EXT:000017653 | denotes | Fog2 |
T8037 | 15842-15852 | GO:0010467 | denotes | expression |
T8038 | 15860-15870 | UBERON:0003104 | denotes | mesenchyme |
T8039 | 15922-15926 | UBERON:0009912 | denotes | lobe |
T8040 | 15946-15951 | UBERON:0009912 | denotes | lobes |
T8041 | 15984-15988 | PR_EXT:000017653 | denotes | Fog2 |
T8042 | 15989-15995 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T8043 | 15996-16000 | NCBITaxon:10088 | denotes | mice |
T8044 | 16023-16033 | GO:0010467 | denotes | expression |
T8045 | 16053-16073 | UBERON:0004883 | denotes | pulmonary mesenchyme |
T8046 | 16111-16124 | GO:0097617 | denotes | hybridization |
T8047 | 16128-16134 | UBERON:0000479 | denotes | tissue |
T8048 | 16419-16429 | UBERON:0001103 | denotes | Diaphragms |
T8049 | 16435-16439 | PR_EXT:000017653 | denotes | Fog2 |
T8050 | 16444-16448 | NCBITaxon:10088 | denotes | mice |
T8051 | 16490-16498 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscular |
T8052 | 16499-16509 | GO_PATO_EXT:biological_patterning_process_or_quality | denotes | patterning |
T8053 | 16557-16566 | UBERON:0001103 | denotes | diaphragm |
T8054 | 16585-16594 | GO_EXT:biological_movement_or_translocation_process | denotes | migratory |
T8055 | 16595-16608 | _FRAGMENT | denotes | population of |
T8056 | 16626-16631 | UBERON_EXT:cell_clump_or_cluster_or_group_or_mass_or_population | denotes | cells |
T8057 | 16609-16615 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscle |
T8058 | 16609-16631 | CL:0000680 | denotes | muscle precursor cells |
T8059 | 16626-16631 | CL_GO_EXT:cell | denotes | cells |
T8060 | 16647-16652 | UBERON:0002101 | denotes | limbs |
T8061 | 16662-16666 | NCBITaxon:10088 | denotes | Mice |
T8062 | 16683-16688 | SO_EXT:0000704 | denotes | genes |
T8063 | 16719-16726 | GO:0065007 | denotes | control |
T8064 | 16760-16768 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscular |
T8065 | 16769-16779 | UBERON:0001103 | denotes | diaphragms |
T8066 | 16792-16802 | CL:0000182 | denotes | Hepatocyte |
T8067 | 16792-16816 | PR_EXT:000008534 | denotes | Hepatocyte growth factor |
T8068 | 16803-16809 | GO_EXT:biological_growth_entity_or_process | denotes | growth |
T8069 | 16803-16816 | GO_EXT:0008083 | denotes | growth factor |
T8070 | 16817-16831 | PR_EXT:000008534 | denotes | Scatter factor |
T8071 | 16833-16836 | PR_EXT:000008534 | denotes | HGF |
T8072 | 16885-16893 | GO_EXT:biological_direction_or_guidance | denotes | guidance |
T8073 | 16897-16903 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscle |
T8074 | 16933-16942 | UBERON:0001103 | denotes | diaphragm |
T8075 | 16967-16970 | PR_EXT:000008534 | denotes | HGF |
T8076 | 16974-16983 | GO:0010467 | denotes | expressed |
T8077 | 16995-17003 | UBERON:0001062 | denotes | anatomic |
T8078 | 17022-17026 | NCBITaxon:10088 | denotes | mice |
T8079 | 17047-17059 | GO_PR_EXT:hepatocyte_growth_factor_receptor | denotes | HGF receptor |
T8080 | 17060-17065 | PR_EXT:000010335 | denotes | c-Met |
T8081 | 17079-17091 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularized |
T8082 | 17092-17114 | UBERON:0009133 | denotes | pleuroperitoneal folds |
T8083 | 17116-17120 | UBERON:0009133 | denotes | PPFs |
T8084 | 17138-17146 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscular |
T8085 | 17147-17157 | UBERON:0001103 | denotes | diaphragms |
T8086 | 17167-17171 | PR_EXT:000017653 | denotes | Fog2 |
T8087 | 17175-17184 | GO:0010467 | denotes | expressed |
T8088 | 17209-17217 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscular |
T8089 | 17218-17227 | UBERON:0001103 | denotes | diaphragm |
T8090 | 17261-17273 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularized |
T8091 | 17274-17283 | UBERON:0001103 | denotes | diaphragm |
T8092 | 17308-17312 | PR_EXT:000012316 | denotes | Pax3 |
T8093 | 17317-17321 | PR_EXT:000010875 | denotes | MyoD |
T8094 | 17323-17336 | GO_EXT:transcription | denotes | transcription |
T8095 | 17323-17344 | GO_EXT:transcription_factor | denotes | transcription factors |
T8096 | 17370-17379 | GO_EXT:biological_movement_or_translocation_process | denotes | migration |
T8097 | 17401-17409 | GO_EXT:muscle_structure_or_tissue_development | denotes | myogenic |
T8098 | 17443-17447 | UBERON:0009133 | denotes | PPFs |
T8099 | 17451-17455 | PR_EXT:000017653 | denotes | Fog2 |
T8100 | 17460-17464 | NCBITaxon:10088 | denotes | mice |
T8101 | 17500-17510 | GO:0010467 | denotes | expression |
T8102 | 17542-17552 | GO:0010467 | denotes | expression |
T8103 | 17556-17559 | PR_EXT:000008534 | denotes | HGF |
T8104 | 17616-17625 | UBERON:0001103 | denotes | diaphragm |
T8105 | 17650-17654 | PR_EXT:000017653 | denotes | Fog2 |
T8106 | 17655-17661 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T8107 | 17662-17666 | NCBITaxon:10088 | denotes | mice |
T8108 | 17699-17703 | PR_EXT:000017653 | denotes | Fog2 |
T8109 | 17769-17772 | PR_EXT:000008534 | denotes | HGF |
T8110 | 17791-17800 | UBERON:0001103 | denotes | diaphragm |
T8111 | 17809-17819 | GO:0065007 | denotes | regulation |
T8112 | 17823-17826 | PR_EXT:000008534 | denotes | HGF |
T8113 | 17827-17837 | GO_PATO_EXT:biological_patterning_process_or_quality | denotes | patterning |
T8114 | 17856-17862 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscle |
T8115 | 17856-17877 | CL:0000680 | denotes | muscle precursor cell |
T8116 | 17873-17877 | CL_GO_EXT:cell | denotes | cell |
T8117 | 17873-17887 | GO:0016477 | denotes | cell migration |
T8118 | 17900-17903 | UBERON:0009133 | denotes | PPF |
T8119 | 17912-17921 | UBERON:0001103 | denotes | diaphragm |
T8120 | 17967-17971 | NCBITaxon:10088 | denotes | mice |
T9833 | 18221-18225 | PR_EXT:000017653 | denotes | FOG2 |
T9834 | 18226-18234 | SO_EXT:sequence_alteration_entity_or_process | denotes | Mutation |
T9835 | 18253-18262 | UBERON:0001103 | denotes | Diaphragm |
T9836 | 18267-18271 | UBERON:0002048 | denotes | Lung |
T9837 | 18286-18290 | PR_EXT:000017653 | denotes | FOG2 |
T9838 | 18291-18299 | SO_EXT:biological_sequence | denotes | sequence |
T9839 | 18334-18340 | UBERON:0000479 | denotes | tissue |
T9840 | 18364-18372 | NCBITaxon_UBERON_EXT:child | denotes | children |
T9841 | 18381-18389 | UBERON:0001062 | denotes | anatomic |
T9842 | 18403-18416 | UBERON:0001103 | denotes | diaphragmatic |
T9843 | 18441-18449 | NCBITaxon_UBERON_EXT:child | denotes | Children |
T9844 | 18637-18650 | UBERON:0001103 | denotes | diaphragmatic |
T9845 | 18677-18690 | UBERON:0001103 | denotes | diaphragmatic |
T9846 | 18703-18718 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T9847 | 18839-18848 | UBERON:0002048 | denotes | Pulmonary |
T9848 | 18879-18883 | UBERON:0002048 | denotes | lung |
T9849 | 18884-18888 | UBERON_EXT:body | denotes | body |
T9850 | 18913-18921 | UBERON:0003215 | denotes | alveolar |
T9851 | 19077-19082 | NCBITaxon_UBERON_EXT:child | denotes | child |
T9852 | 19112-19116 | PR_EXT:000017653 | denotes | FOG2 |
T9853 | 19117-19125 | SO_EXT:biological_sequence | denotes | sequence |
T9854 | 19126-19132 | SO_EXT:sequence_alteration_entity_or_process | denotes | change |
T9855 | 19170-19174 | UBERON_EXT:baby_or_infant | denotes | baby |
T9856 | 19175-19179 | NCBITaxon_UBERON_EXT:girl | denotes | girl |
T9857 | 19201-19212 | UBERON:0001004 | denotes | respiratory |
T9858 | 19224-19229 | GO:0007567 | denotes | birth |
T9859 | 19234-19238 | GO:0016265 | denotes | died |
T9860 | 19271-19277 | GO:0016265 | denotes | mortem |
T9861 | 19307-19311 | UBERON:0002048 | denotes | lung |
T9862 | 19332-19337 | UBERON:0000160 | denotes | bowel |
T9863 | 19345-19350 | UBERON:0001443 | denotes | chest |
T9864 | 19447-19456 | UBERON:0002048 | denotes | pulmonary |
T9865 | 19478-19482 | UBERON:0002048 | denotes | lung |
T9866 | 19512-19516 | UBERON_EXT:body | denotes | body |
T9867 | 19582-19591 | UBERON:0002168 | denotes | left lung |
T9868 | 19597-19601 | UBERON:0002048 | denotes | lung |
T9869 | 19602-19606 | UBERON_EXT:body | denotes | body |
T9870 | 19687-19696 | UBERON_EXT:bronchiole_or_bronchus | denotes | bronchial |
T9871 | 19725-19733 | UBERON:0003215 | denotes | alveolar |
T9872 | 19791-19795 | UBERON:0002048 | denotes | lung |
T9873 | 19835-19848 | UBERON:0001103 | denotes | diaphragmatic |
T9874 | 19909-19921 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularized |
T9875 | 19922-19933 | UBERON:0000211 | denotes | ligamentous |
T9876 | 19951-19964 | UBERON:0001103 | denotes | diaphragmatic |
T9877 | 19988-20000 | _FRAGMENT | denotes | left lobe of |
T9878 | 20005-20010 | UBERON:0001115 | denotes | liver |
T9879 | 20042-20047 | UBERON:0002107 | denotes | liver |
T9880 | 20088-20097 | UBERON:0001103 | denotes | diaphragm |
T9881 | 20112-20124 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularized |
T9882 | 20213-20218 | UBERON:0000948 | denotes | heart |
T9883 | 20275-20280 | UBERON:0003978 | denotes | valve |
T9884 | 20290-20298 | SO_EXT:biological_sequence | denotes | Sequence |
T9885 | 20319-20327 | CHEBI_EXT:cytosine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | cytosine |
T9886 | 20331-20338 | CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | thymine |
T9887 | 20352-20358 | SO_EXT:sequence_alteration_entity_or_process | denotes | change |
T9888 | 20362-20366 | SO_EXT:0000147 | denotes | exon |
T9889 | 20374-20381 | SO_EXT:sequence_alteration_process | denotes | changes |
T9890 | 20392-20402 | CHEBI_SO_EXT:amino_acid | denotes | amino acid |
T9891 | 20408-20416 | CHEBI_SO_EXT:arginine | denotes | arginine |
T9892 | 20422-20432 | SO_EXT:0000319 | denotes | stop codon |
T9893 | 20439-20447 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T9894 | 20468-20477 | SO_EXT:sequence_truncation_process | denotes | truncated |
T9895 | 20478-20485 | CHEBI_SO_EXT:peptide_or_peptide_region | denotes | peptide |
T9896 | 20508-20512 | CHEBI_EXT:zinc | denotes | zinc |
T9897 | 20520-20527 | SO_EXT:0000417 | denotes | domains |
T9898 | 20545-20549 | CHEBI_SO_EXT:base | denotes | base |
T9899 | 20550-20556 | SO_EXT:sequence_alteration_entity_or_process | denotes | change |
T9900 | 20592-20595 | CHEBI_SO_EXT:DNA | denotes | DNA |
T9901 | 20612-20618 | UBERON:0007023 | denotes | adults |
T9902 | 20654-20662 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T9903 | 20762-20770 | SO_EXT:biological_sequence | denotes | sequence |
T9904 | 20826-20834 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T9905 | 20875-20883 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T9906 | 20887-20891 | PR_EXT:000017653 | denotes | FOG2 |
T12833 | 21289-21302 | UBERON:0001103 | denotes | diaphragmatic |
T12834 | 21411-21427 | UBERON:0012101 | denotes | perinatal period |
T12835 | 21415-21420 | GO:0007567 | denotes | natal |
T12836 | 21454-21467 | UBERON:0001103 | denotes | diaphragmatic |
T12837 | 21500-21515 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T12838 | 21800-21809 | UBERON:0001103 | denotes | diaphragm |
T12839 | 21815-21830 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T12840 | 21882-21887 | GO:0007567 | denotes | natal |
T12841 | 21906-21911 | GO:0007567 | denotes | natal |
T12842 | 21912-21917 | UBERON:0001443 | denotes | chest |
T12843 | 21945-21958 | UBERON:0001103 | denotes | diaphragmatic |
T12844 | 21959-21974 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T12845 | 22122-22130 | PATO_UBERON_EXT:neonate_or_newborn | denotes | neonatal |
T12846 | 22346-22355 | UBERON:0000916 | denotes | abdominal |
T12847 | 22386-22395 | UBERON:0002048 | denotes | pulmonary |
T12848 | 22411-22422 | UBERON:0001004 | denotes | respiratory |
T12849 | 22455-22465 | GO_SO_EXT:chromosome | denotes | chromosome |
T12850 | 22527-22536 | UBERON:0001103 | denotes | diaphragm |
T12851 | 22560-22565 | NCBITaxon:9606 | denotes | Human |
T12852 | 22566-22570 | PR_EXT:000017653 | denotes | FOG2 |
T12853 | 22579-22589 | GO_SO_EXT:chromosome | denotes | Chromosome |
T12854 | 22638-22647 | UBERON:0001103 | denotes | diaphragm |
T12855 | 22660-22674 | GO_SO_EXT:sequence_rearrangement_entity_or_process | denotes | rearrangements |
T12856 | 22799-22813 | GO_EXT:biological_translocation_entity_or_process | denotes | translocations |
T12857 | 22829-22833 | PR_EXT:000017653 | denotes | FOG2 |
T12858 | 22881-22890 | SO_EXT:sequence_deletion_entity_or_process | denotes | deletions |
T12859 | 22919-22923 | PR_EXT:000017653 | denotes | FOG2 |
T12860 | 22935-22939 | GO:0016265 | denotes | died |
T12861 | 23019-23023 | SO_EXT:0000704 | denotes | gene |
T12862 | 23031-23042 | GO_SO_EXT:chromosome | denotes | chromosomal |
T12863 | 23043-23056 | GO_SO_EXT:sequence_rearrangement_entity_or_process | denotes | rearrangement |
T12864 | 23060-23068 | SO_EXT:sequence_deletion_entity_or_process | denotes | deletion |
T12865 | 23100-23104 | SO_EXT:sequence_nullness | denotes | null |
T12866 | 23105-23113 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T12867 | 23174-23178 | PR_EXT:000017653 | denotes | FOG2 |
T12868 | 23179-23187 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T12869 | 23235-23244 | UBERON:0002048 | denotes | pulmonary |
T12870 | 23249-23262 | UBERON:0001103 | denotes | diaphragmatic |
T12871 | 23291-23296 | NCBITaxon:10088 | denotes | mouse |
T12872 | 23301-23306 | NCBITaxon:9606 | denotes | human |
T12873 | 23329-23337 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T12874 | 23341-23345 | PR_EXT:000017653 | denotes | FOG2 |
T12875 | 23379-23384 | NCBITaxon:9606 | denotes | human |
T12876 | 23399-23412 | UBERON:0001103 | denotes | diaphragmatic |
T12877 | 23417-23426 | UBERON:0002048 | denotes | pulmonary |
T12878 | 23463-23468 | NCBITaxon_UBERON_EXT:child | denotes | child |
T12879 | 23470-23474 | NCBITaxon:10088 | denotes | mice |
T12880 | 23494-23498 | SO_EXT:sequence_nullness | denotes | null |
T12881 | 23499-23507 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T12882 | 23511-23515 | PR_EXT:000017653 | denotes | Fog2 |
T12883 | 23614-23618 | SO_EXT:0000704 | denotes | gene |
T12884 | 23679-23685 | NCBITaxon:9606 | denotes | humans |
T12885 | 23691-23695 | NCBITaxon:10088 | denotes | mice |
T12886 | 23724-23728 | PR_EXT:000017653 | denotes | Fog2 |
T12887 | 23729-23742 | UBERON:0001103 | denotes | diaphragmatic |
T12888 | 23851-23857 | UBERON_EXT:muscle_structure_or_tissue | denotes | Muscle |
T12889 | 23894-23903 | UBERON:0001103 | denotes | diaphragm |
T12890 | 23904-23911 | GO_EXT:biological_movement_or_translocation_process | denotes | migrate |
T12891 | 23929-23941 | UBERON:0004290 | denotes | dermomyotome |
T12892 | 23945-23953 | UBERON:0005434 | denotes | cervical |
T12893 | 23954-23961 | UBERON:0002329 | denotes | somites |
T12894 | 23972-23981 | GO_EXT:biological_movement_or_translocation_process | denotes | migration |
T12895 | 23991-24000 | UBERON:0001103 | denotes | diaphragm |
T12896 | 24020-24023 | UBERON:0009133 | denotes | PPF |
T12897 | 24040-24046 | UBERON:0000479 | denotes | tissue |
T12898 | 24085-24094 | UBERON:0000309 | denotes | body wall |
T12899 | 24102-24122 | UBERON:0003283 | denotes | esophageal mesentery |
T12900 | 24152-24170 | UBERON:0004161 | denotes | septum transversum |
T12901 | 24177-24183 | UBERON_EXT:muscle_structure_or_tissue | denotes | Muscle |
T12902 | 24205-24208 | UBERON:0009133 | denotes | PPF |
T12903 | 24228-24239 | GO:0008283 | denotes | proliferate |
T12904 | 24241-24254 | GO_RO_EXT:developmental_differentiation_process | denotes | differentiate |
T12905 | 24265-24272 | GO_EXT:biological_movement_or_translocation_process | denotes | migrate |
T12906 | 24297-24303 | UBERON:0002228 | denotes | costal |
T12907 | 24305-24312 | UBERON:0000975 | denotes | sternal |
T12908 | 24313-24319 | UBERON:0002228 | denotes | costal |
T12909 | 24325-24331 | UBERON:0000978 | denotes | crural |
T12910 | 24358-24367 | UBERON:0001103 | denotes | diaphragm |
T12911 | 24387-24390 | UBERON:0009133 | denotes | PPF |
T12912 | 24438-24450 | _FRAGMENT | denotes | formation of |
T12913 | 24455-24464 | GO:0060539 | denotes | diaphragm |
T12914 | 24455-24464 | UBERON:0001103 | denotes | diaphragm |
T12915 | 24494-24498 | PR_EXT:000017653 | denotes | Fog2 |
T12916 | 24499-24505 | SO_EXT:sequence_altered_entity | denotes | mutant |
T12917 | 24539-24542 | PR_EXT:000008534 | denotes | HGF |
T12918 | 24543-24553 | GO:0010467 | denotes | expression |
T12919 | 24582-24588 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscle |
T12920 | 24582-24604 | CL:0000680 | denotes | muscle precursor cells |
T12921 | 24599-24604 | CL_GO_EXT:cell | denotes | cells |
T12922 | 24605-24612 | GO_EXT:biological_movement_or_translocation_process | denotes | migrate |
T12923 | 24633-24642 | UBERON:0001103 | denotes | diaphragm |
T12924 | 24688-24697 | GO_PATO_EXT:biological_patterning_process_or_quality | denotes | patterned |
T12925 | 24698-24704 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscle |
T12926 | 24726-24730 | PR_EXT:000017653 | denotes | Fog2 |
T12927 | 24731-24737 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T12928 | 24738-24747 | UBERON:0001103 | denotes | diaphragm |
T12929 | 24758-24762 | PR_EXT:000012316 | denotes | Pax3 |
T12930 | 24767-24771 | PR_EXT:000010875 | denotes | MyoD |
T12931 | 24772-24782 | GO:0010467 | denotes | expression |
T12932 | 24802-24805 | UBERON:0009133 | denotes | PPF |
T12933 | 24830-24843 | GO_EXT:transcription | denotes | transcription |
T12934 | 24830-24851 | GO_EXT:transcription_factor | denotes | transcription factors |
T12935 | 24868-24874 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscle |
T12936 | 24868-24889 | CL:0000680 | denotes | muscle precursor cell |
T12937 | 24885-24889 | CL_GO_EXT:cell | denotes | cell |
T12938 | 24885-24899 | GO:0016477 | denotes | cell migration |
T12939 | 24885-24889 | _FRAGMENT | denotes | cell |
T12940 | 24904-24919 | GO:0030154 | denotes | differentiation |
T12941 | 24958-24961 | UBERON:0009133 | denotes | PPF |
T12942 | 24987-24993 | UBERON_EXT:muscle_structure_or_tissue | denotes | muscle |
T12943 | 24987-25008 | CL:0000680 | denotes | muscle precursor cell |
T12944 | 25004-25008 | CL_GO_EXT:cell | denotes | cell |
T12945 | 25004-25018 | GO:0016477 | denotes | cell migration |
T12946 | 25031-25034 | UBERON:0009133 | denotes | PPF |
T12947 | 25054-25063 | UBERON:0001103 | denotes | diaphragm |
T12948 | 25065-25069 | PR_EXT:000017653 | denotes | Fog2 |
T12949 | 25113-25120 | PR_EXT:000007857 | denotes | Gatas 1 |
T12950 | 25113-25118 | _FRAGMENT | denotes | Gatas |
T12951 | 25121-25122 | PR_EXT:000007861 | denotes | 6 |
T12952 | 25141-25154 | GO_EXT:transcription | denotes | transcription |
T12953 | 25141-25162 | GO_EXT:transcription_factor | denotes | transcription factors |
T12954 | 25171-25179 | PR_EXT:000011405 | denotes | CoupTFII |
T12955 | 25208-25212 | PR_EXT:000017653 | denotes | Fog2 |
T12956 | 25213-25218 | PR_EXT:000007859 | denotes | Gata4 |
T12957 | 25254-25261 | UBERON:0000948 | denotes | cardiac |
T12958 | 25254-25261 | _FRAGMENT | denotes | cardiac |
T12959 | 25274-25285 | GO:0007507 | denotes | development |
T12960 | 25266-25273 | UBERON:0000991 | denotes | gonadal |
T12961 | 25266-25285 | GO:0008406 | denotes | gonadal development |
T12962 | 25318-25322 | UBERON:0002048 | denotes | lung |
T12963 | 25327-25336 | UBERON:0001103 | denotes | diaphragm |
T12964 | 25383-25392 | UBERON:0002048 | denotes | pulmonary |
T12965 | 25466-25475 | UBERON:0001103 | denotes | diaphragm |
T12966 | 25484-25493 | UBERON:0002048 | denotes | Pulmonary |
T12967 | 25533-25546 | UBERON:0001103 | denotes | diaphragmatic |
T12968 | 25547-25554 | UBERON:0001062 | denotes | anatomy |
T12969 | 25639-25652 | UBERON:0001103 | denotes | diaphragmatic |
T12970 | 25683-25698 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T12971 | 25707-25720 | UBERON:0001884 | denotes | phrenic nerve |
T12972 | 25830-25834 | NCBITaxon:9940 | denotes | lamb |
T12973 | 25882-25891 | UBERON:0002048 | denotes | pulmonary |
T12974 | 25882-25905 | GO:0030324 | denotes | pulmonary developmental |
T12975 | 25958-25971 | UBERON:0001103 | denotes | diaphragmatic |
T12976 | 26020-26031 | CHEBI_EXT:50905 | denotes | teratogenic |
T12977 | 26159-26164 | UBERON:0009912 | denotes | lobar |
T12978 | 26295-26304 | UBERON:0002048 | denotes | pulmonary |
T12979 | 26334-26338 | NCBITaxon:10088 | denotes | mice |
T12980 | 26348-26357 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutations |
T12981 | 26361-26365 | PR_EXT:000017653 | denotes | Fog2 |
T12982 | 26407-26411 | UBERON:0002048 | denotes | lung |
T12983 | 26407-26423 | GO:0030324 | denotes | lung development |
T12984 | 26471-26475 | UBERON:0009912 | denotes | lobe |
T12985 | 26513-26517 | UBERON:0009912 | denotes | lobe |
T12986 | 26532-26537 | UBERON:0009912 | denotes | lobar |
T12987 | 26570-26574 | PR_EXT:000017653 | denotes | Fog2 |
T12988 | 26575-26585 | GO:0010467 | denotes | expression |
T12989 | 26607-26612 | UBERON:0009912 | denotes | lobar |
T12990 | 26628-26632 | PR_EXT:000017653 | denotes | Fog2 |
T12991 | 26633-26643 | GO:0010467 | denotes | expression |
T12992 | 26662-26682 | UBERON:0004883 | denotes | pulmonary mesenchyme |
T12993 | 26689-26694 | UBERON:0009912 | denotes | lobar |
T12994 | 26753-26762 | GO:0010467 | denotes | expressed |
T12995 | 26770-26780 | UBERON:0003104 | denotes | mesenchyme |
T12996 | 26810-26814 | UBERON:0009912 | denotes | lobe |
T12997 | 26843-26848 | UBERON:0009912 | denotes | lobes |
T12998 | 26898-26902 | UBERON:0009912 | denotes | lobe |
T12999 | 26917-26921 | UBERON:0009912 | denotes | lobe |
T13000 | 26946-26950 | PR_EXT:000017653 | denotes | Fog2 |
T13001 | 26966-26976 | GO_PATO_EXT:biological_patterning_process_or_quality | denotes | patterning |
T13002 | 27008-27013 | UBERON:0009912 | denotes | lobes |
T13003 | 27048-27052 | PR_EXT:000017653 | denotes | Fog2 |
T13004 | 27094-27098 | PR_EXT:000017653 | denotes | Fog2 |
T13005 | 27099-27104 | UBERON:0002048 | denotes | lungs |
T13006 | 27196-27200 | PR_EXT:000017653 | denotes | Fog2 |
T13007 | 27201-27206 | UBERON:0002048 | denotes | lungs |
T13008 | 27267-27272 | UBERON:0009912 | denotes | lobes |
T13009 | 27312-27321 | SO_EXT:wild_type_entity_or_quality | denotes | wild-type |
T13010 | 27322-27327 | UBERON:0002048 | denotes | lungs |
T13011 | 27381-27389 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T13012 | 27393-27397 | PR_EXT:000017653 | denotes | Fog2 |
T13013 | 27405-27410 | NCBITaxon:10088 | denotes | mouse |
T13014 | 27444-27457 | UBERON:0001103 | denotes | diaphragmatic |
T13015 | 27458-27473 | GO_EXT:muscle_structure_or_tissue_development | denotes | muscularization |
T13016 | 27486-27495 | UBERON:0002048 | denotes | pulmonary |
T13017 | 27542-27550 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T13018 | 27559-27563 | SO_EXT:0000704 | denotes | gene |
T13019 | 27585-27591 | GO_EXT:fatality_or_lethality | denotes | lethal |
T13020 | 27602-27606 | UBERON:0002048 | denotes | lung |
T13021 | 27602-27606 | _FRAGMENT | denotes | lung |
T13022 | 27621-27632 | GO:0030324 | denotes | development |
T13023 | 27611-27620 | UBERON:0001103 | denotes | diaphragm |
T13024 | 27611-27632 | GO:0060539 | denotes | diaphragm development |
T13025 | 27638-27643 | NCBITaxon_UBERON_EXT:child | denotes | child |
T13026 | 27695-27699 | PR_EXT:000017653 | denotes | Fog2 |
T13027 | 27700-27707 | CHEBI_GO_EXT:biological_process_or_quality_or_role | denotes | biology |
T13028 | 27732-27736 | PR_EXT:000017653 | denotes | Fog2 |
T13029 | 27747-27752 | NCBITaxon:10088 | denotes | mouse |
T13030 | 27766-27775 | UBERON:0001103 | denotes | diaphragm |
T13031 | 27766-27775 | _FRAGMENT | denotes | diaphragm |
T13032 | 27785-27796 | GO:0060539 | denotes | development |
T13033 | 27780-27784 | UBERON:0002048 | denotes | lung |
T13034 | 27780-27796 | GO:0030324 | denotes | lung development |
T13035 | 27974-27983 | CHEBI_EXT:polyatomic_entity_or_group | denotes | molecular |
T13036 | 28016-28021 | NCBITaxon:9606 | denotes | human |
T14384 | 28325-28332 | SO_EXT:0000704 | denotes | Genetic |
T14385 | 28348-28353 | NCBITaxon:10088 | denotes | mouse |
T14386 | 28354-28362 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T14387 | 28376-28384 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T14388 | 28425-28434 | SO_EXT:wild_type_entity_or_quality | denotes | Wild-type |
T14389 | 28454-28458 | NCBITaxon:10088 | denotes | mice |
T14390 | 28468-28475 | SO_EXT:0000704 | denotes | genetic |
T14391 | 28562-28566 | NCBITaxon:10088 | denotes | Mice |
T14392 | 28578-28582 | SO_EXT:sequence_nullness | denotes | null |
T14393 | 28583-28591 | SO_EXT:sequence_alteration_entity_or_process | denotes | mutation |
T14394 | 28595-28599 | PR_EXT:000017653 | denotes | Fog2 |
T14395 | 28613-28617 | SO_EXT:0000704 | denotes | gene |
T15241 | 28704-28708 | NCBITaxon:10088 | denotes | mice |
T15242 | 28716-28727 | GO:0007565 | denotes | pregnancies |
T15243 | 28770-28777 | UBERON:0000922 | denotes | embryos |
T15244 | 28779-28786 | UBERON:0000922 | denotes | Embryos |
T15245 | 28866-28873 | UBERON:0000922 | denotes | embryos |
T15246 | 28941-28950 | UBERON:0001103 | denotes | diaphragm |
T15247 | 28952-28957 | UBERON:0002048 | denotes | lungs |
T15248 | 28963-28968 | UBERON:0000948 | denotes | heart |
T15249 | 28988-28993 | UBERON:0002048 | denotes | lungs |
T15250 | 28998-29019 | UBERON:0007196 | denotes | tracheobronchial tree |
T15251 | 29052-29062 | UBERON:0001103 | denotes | diaphragms |
T15252 | 29088-29096 | UBERON:0000915 | denotes | thoracic |
T15253 | 29097-29103 | UBERON:0000479 | denotes | tissue |
T15254 | 29125-29132 | UBERON:0000922 | denotes | embryos |
T15255 | 29138-29142 | UBERON:0002048 | denotes | lung |
T15256 | 29160-29165 | UBERON:0002048 | denotes | lungs |
T15257 | 29192-29199 | UBERON:0000922 | denotes | embryos |
T15258 | 29254-29263 | CHEBI_EXT:polyester | denotes | polyester |
T15259 | 29346-29354 | CHEBI_EXT:33284 | denotes | nutrient |
T15260 | 29355-29362 | CHEBI:60004 | denotes | mixture |
T15261 | 29454-29460 | NCBITaxon:27592 | denotes | bovine |
T15262 | 29461-29466 | UBERON:0001977 | denotes | serum |
T15263 | 29478-29489 | CHEBI_EXT:L_glutamine | denotes | L-glutamine |
T15264 | 29480-29489 | CHEBI_SO_EXT:glutamine | denotes | glutamine |
T15265 | 29504-29514 | CHEBI:17334 | denotes | penicillin |
T15266 | 29527-29539 | CHEBI:17076 | denotes | streptomycin |
T15267 | 29557-29571 | CHEBI:2682 | denotes | amphotericin B |
T15268 | 29573-29577 | UBERON:0002048 | denotes | Lung |
T15269 | 29624-29627 | CHEBI:16526 | denotes | CO2 |
T15270 | 29779-29789 | SO_EXT:transgenic_entity | denotes | Transgenic |
T15271 | 29790-29794 | NCBITaxon:10088 | denotes | mice |
T15272 | 29808-29812 | PR_EXT:000033987 | denotes | lacZ |
T15273 | 29813-29817 | SO_EXT:0000704 | denotes | gene |
T15274 | 29832-29836 | PR_EXT:000017653 | denotes | Fog2 |
T15275 | 29837-29845 | SO_EXT:0000167 | denotes | promoter |
T15276 | 29891-29898 | NCBITaxon:33208 | denotes | animals |
T15277 | 29904-29908 | PR_EXT:000033987 | denotes | lacZ |
T15278 | 29909-29913 | SO_EXT:0000704 | denotes | gene |
T15279 | 29954-29958 | PR_EXT:000017653 | denotes | Fog2 |
T15280 | 29974-29989 | GO_EXT:0004565 | denotes | β-galactosidase |
T15281 | 29990-30000 | GO:0010467 | denotes | expression |
T15282 | 30006-30012 | SO_EXT:sequence_fusion_entity_or_process | denotes | fusion |
T15283 | 30013-30020 | CHEBI_PR_EXT:protein | denotes | protein |
T15284 | 30021-30029 | SO:0001817 | denotes | in frame |
T15285 | 30049-30060 | CHEBI_SO_EXT:amino_acid | denotes | amino acids |
T15286 | 30068-30072 | PR_EXT:000017653 | denotes | FOG2 |
T15287 | 30073-30080 | CHEBI_PR_EXT:protein | denotes | protein |
T15288 | 30086-30090 | PR_EXT:000017653 | denotes | Fog2 |
T15289 | 30091-30095 | PR_EXT:000033987 | denotes | lacZ |
T15290 | 30121-30125 | SO_EXT:0000243 | denotes | ires |
T15291 | 30131-30139 | SO_EXT:0005853 | denotes | cassette |
T15292 | 30156-30160 | SO_EXT:sequence_nullness | denotes | null |
T15293 | 30161-30167 | SO_EXT:0001023 | denotes | allele |
T15294 | 30171-30175 | PR_EXT:000017653 | denotes | Fog2 |
T15295 | 30176-30180 | SO_EXT:0000704 | denotes | gene |
T15296 | 30186-30190 | PR_EXT:000017653 | denotes | Fog2 |
T15297 | 30191-30195 | PR_EXT:000033987 | denotes | LacZ |
T15298 | 30201-30210 | SO_EXT:engineered_biological_sequence | denotes | construct |
T15299 | 30215-30225 | SO_EXT:sequence_linearization | denotes | linearized |
T15300 | 30268-30276 | CL:0002322 | denotes | ES cells |
T15301 | 30271-30276 | CL_GO_EXT:cell | denotes | cells |
T15302 | 30301-30306 | SO_EXT:sequence_cloned_entity | denotes | clone |
T15303 | 30377-30388 | UBERON:0000358 | denotes | blastocysts |
T15304 | 30390-30394 | PR_EXT:000017653 | denotes | Fog2 |
T15305 | 30395-30399 | PR_EXT:000033987 | denotes | lacZ |
T15306 | 30405-30412 | NCBITaxon:33208 | denotes | animals |
T15307 | 30467-30471 | PR_EXT:000033987 | denotes | lacZ |
T15308 | 30472-30482 | GO:0010467 | denotes | Expression |
T15309 | 30502-30511 | UBERON:0000922 | denotes | embryonic |
T15310 | 30512-30517 | UBERON:0002048 | denotes | lungs |
T15311 | 30547-30562 | GO_EXT:0015925 | denotes | β-galactosidase |
T15312 | 30577-30582 | CHEBI:75055 | denotes | X-gal |
T15974 | 30611-30613 | GO_EXT:reverse_transcription_or_reverse_transcriptase | denotes | RT |
T15975 | 30622-30630 | SO_EXT:biological_sequence | denotes | sequence |
T15976 | 30647-30652 | NCBITaxon:10088 | denotes | mouse |
T15977 | 30654-30657 | CHEBI_SO_EXT:RNA | denotes | RNA |
T15978 | 30700-30708 | UBERON:0000915 | denotes | thoracic |
T15979 | 30709-30725 | UBERON:0005291 | denotes | embryonic tissue |
T15980 | 30727-30729 | GO_EXT:reverse_transcription_or_reverse_transcriptase | denotes | RT |
T15981 | 30758-30764 | SO_EXT:0000112 | denotes | primer |
T15982 | 30792-30796 | PR_EXT:000017653 | denotes | Fog2 |
T15983 | 30797-30801 | SO_EXT:0000704 | denotes | gene |
T15984 | 30803-30805 | GO_EXT:reverse_transcription_or_reverse_transcriptase | denotes | RT |
T15985 | 30828-30840 | CHEBI_EXT:radiolabel_process | denotes | radiolabeled |
T15986 | 30841-30848 | SO_EXT:0000112 | denotes | primers |
T15987 | 30874-30881 | GO:0008380 | denotes | spliced |
T15988 | 30882-30891 | _FRAGMENT | denotes | region of |
T15989 | 30896-30900 | SO_EXT:0000842 | denotes | gene |
T15990 | 30942-30952 | GO_EXT:macromolecule_denaturation | denotes | denaturing |
T15991 | 31006-31008 | GO_EXT:reverse_transcription_or_reverse_transcriptase | denotes | RT |
T15992 | 31009-31020 | SO_EXT:0000006 | denotes | PCR product |
T15993 | 31025-31031 | SO_EXT:sequence_cloning_process | denotes | cloned |
T15994 | 31044-31050 | SO_EXT:0000440 | denotes | vector |
T15995 | 31065-31072 | SO_EXT:sequence_cloning_process | denotes | Cloning |
T15996 | 31147-31151 | SO_EXT:0000704 | denotes | gene |
T15997 | 31161-31168 | SO_EXT:0000112 | denotes | primers |
T15998 | 31170-31178 | SO_EXT:biological_sequence | denotes | Sequence |
T15999 | 31219-31223 | SO_EXT:0000704 | denotes | Gene |
T16277 | 31277-31290 | GO:0097617 | denotes | hybridization |
T16278 | 31336-31339 | CHEBI:73702 | denotes | wax |
T16279 | 31393-31406 | GO:0097617 | denotes | hybridization |
T16280 | 31426-31432 | CHEBI_SO_EXT:molecular_probe | denotes | Probes |
T16281 | 31433-31440 | CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process | denotes | labeled |
T16282 | 31446-31449 | CHEBI:37983 | denotes | 35S |
T16283 | 31475-31488 | GO_EXT:transcription | denotes | transcription |
T16284 | 31492-31502 | SO_EXT:sequence_linearization | denotes | linearized |
T16285 | 31503-31510 | SO_EXT:0000155 | denotes | plasmid |
T16286 | 31525-31535 | GO:0097617 | denotes | hybridized |
T16287 | 31539-31545 | UBERON:0000479 | denotes | tissue |
T16288 | 31556-31562 | GO:0005634 | denotes | Nuclei |
T16662 | 31670-31675 | NCBITaxon:9606 | denotes | Human |
T16663 | 31676-31679 | CHEBI_SO_EXT:DNA | denotes | DNA |
T16664 | 31695-31703 | SO_EXT:biological_sequence | denotes | sequence |
T16665 | 31714-31717 | CHEBI_SO_EXT:DNA | denotes | DNA |
T16666 | 31755-31761 | CHEBI:15882 | denotes | phenol |
T16667 | 31762-31772 | CHEBI:35255 | denotes | chloroform |
T16668 | 31809-31816 | UBERON:0000479 | denotes | tissues |
T16669 | 31841-31848 | SO_EXT:0000112 | denotes | Primers |
T16670 | 31874-31878 | PR_EXT:000017653 | denotes | FOG2 |
T16671 | 31879-31891 | SO_EXT:0000195 | denotes | coding exons |
T16672 | 31900-31902 | SO_EXT:0000028 | denotes | bp |
T16673 | 31906-31914 | SO:0000357 | denotes | flanking |
T16674 | 31915-31923 | SO_EXT:sequence_upstreamness | denotes | upstream |
T16675 | 31928-31938 | SO_EXT:sequence_downstreamness | denotes | downstream |
T16676 | 31939-31947 | SO_EXT:biological_sequence | denotes | sequence |
T16677 | 32018-32024 | SO_EXT:0000112 | denotes | Primer |
T16678 | 32025-32034 | SO_EXT:biological_sequence | denotes | sequences |
T16679 | 32064-32072 | SO_EXT:biological_sequence | denotes | Sequence |
T16680 | 32112-32116 | SO_EXT:0000704 | denotes | Gene |
T16681 | 32125-32128 | CHEBI_SO_EXT:DNA | denotes | DNA |
T16682 | 32194-32199 | UBERON:0000178 | denotes | blood |
T16683 | 32225-32230 | UBERON:0000178 | denotes | blood |
T16684 | 32292-32295 | CHEBI_SO_EXT:DNA | denotes | DNA |
T16685 | 32423-32430 | CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag | denotes | markers |
T16686 | 32432-32435 | SO_EXT:0000694 | denotes | SNP |
T16687 | 32490-32498 | OBI_SO_EXT:gene_or_genetic_investigation_or_genetic_process | denotes | Genetics |
T2496 | 3096-3101 | GO:0007567 | denotes | birth |
T8009 | 14305-14309 | UBERON:0002048 | denotes | lung |
R2 | T942 | T941 | _lexicallyChainedTo | Development,Diaphragm |
R236 | T2553 | T2552 | _lexicallyChainedTo | development,diaphragmatic |
R1802 | T7956 | T7955 | _lexicallyChainedTo | Development,Lung |
R1803 | T7965 | T7964 | _lexicallyChainedTo | development,pulmonary |
R1804 | T8056 | T8055 | _lexicallyChainedTo | cells,population of |
R2525 | T9878 | T9877 | _lexicallyChainedTo | liver,left lobe of |
R3002 | T12913 | T12912 | _lexicallyChainedTo | diaphragm,formation of |
R3003 | T12940 | T12939 | _lexicallyChainedTo | differentiation,cell |
R3004 | T12951 | T12950 | _lexicallyChainedTo | 6,Gatas |
R3005 | T12959 | T12958 | _lexicallyChainedTo | development,cardiac |
R3006 | T13022 | T13021 | _lexicallyChainedTo | development,lung |
R3007 | T13032 | T13031 | _lexicallyChainedTo | development,diaphragm |
R4580 | T15989 | T15988 | _lexicallyChainedTo | gene,region of |
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5761 | 8858-8861 | DT | denotes | the |
T5762 | 8869-8876 | NN | denotes | surface |
T5763 | 8862-8868 | JJ | denotes | entire |
T5764 | 8877-8879 | IN | denotes | of |
T5765 | 8880-8883 | DT | denotes | the |
T5766 | 8889-8894 | NNS | denotes | walls |
T5767 | 8884-8888 | NN | denotes | body |
T5768 | 8895-8896 | -LRB- | denotes | ( |
T5769 | 8896-8902 | NN | denotes | Figure |
T5770 | 8903-8905 | CD | denotes | 1B |
T5771 | 8905-8906 | -RRB- | denotes | ) |
T5772 | 8906-8907 | . | denotes | . |
T5773 | 8907-9506 | sentence | denotes | Figure 1 Abnormal Pulmonary and Diaphragmatic Development in the lil Mouse (A) The mutant hypoplastic lung (right) lacks the development of the accessory lobe and the anterior portion of the right middle lobe (marked with arrows on the control sample on the left). (B) Whole diaphragms show a lack of normal muscularization in the posterolateral regions and the peripheral regions of the mutant diaphragm (control on left and lil diaphragm on the right). The number of lil mutant mice that survived to birth was less than 5% of total progeny, rather than the 25% expected for a recessive mutation. |
T5774 | 9364-9367 | DT | denotes | The |
T5775 | 9368-9374 | NN | denotes | number |
T5776 | 9417-9420 | VBD | denotes | was |
T5777 | 9375-9377 | IN | denotes | of |
T5778 | 9378-9381 | NN | denotes | lil |
T5779 | 9389-9393 | NNS | denotes | mice |
T5780 | 9382-9388 | NN | denotes | mutant |
T5781 | 9394-9398 | WDT | denotes | that |
T5782 | 9399-9407 | VBD | denotes | survived |
T5783 | 9408-9410 | IN | denotes | to |
T5784 | 9411-9416 | NN | denotes | birth |
T5785 | 9421-9425 | JJR | denotes | less |
T5786 | 9431-9432 | CD | denotes | 5 |
T5787 | 9426-9430 | IN | denotes | than |
T5788 | 9432-9433 | NN | denotes | % |
T5789 | 9434-9436 | IN | denotes | of |
T5790 | 9437-9442 | JJ | denotes | total |
T5791 | 9443-9450 | NN | denotes | progeny |
T5792 | 9450-9452 | , | denotes | , |
T5793 | 9452-9458 | RB | denotes | rather |
T5794 | 9459-9463 | IN | denotes | than |
T5795 | 9464-9467 | DT | denotes | the |
T5796 | 9470-9471 | NN | denotes | % |
T5797 | 9468-9470 | CD | denotes | 25 |
T5798 | 9472-9480 | VBN | denotes | expected |
T5799 | 9481-9484 | IN | denotes | for |
T5800 | 9485-9486 | DT | denotes | a |
T5801 | 9497-9505 | NN | denotes | mutation |
T5802 | 9487-9496 | JJ | denotes | recessive |
T5803 | 9505-9506 | . | denotes | . |
T5804 | 9506-9635 | sentence | denotes | We evaluated litters at different embryonic time points to determine whether the reduced number was due to intra-uterine demise. |
T5805 | 9507-9509 | PRP | denotes | We |
T5806 | 9510-9519 | VBD | denotes | evaluated |
T5807 | 9520-9527 | NNS | denotes | litters |
T5808 | 9528-9530 | IN | denotes | at |
T5809 | 9531-9540 | JJ | denotes | different |
T5810 | 9556-9562 | NNS | denotes | points |
T5811 | 9541-9550 | JJ | denotes | embryonic |
T5812 | 9551-9555 | NN | denotes | time |
T5813 | 9563-9565 | TO | denotes | to |
T5814 | 9566-9575 | VB | denotes | determine |
T5815 | 9576-9583 | IN | denotes | whether |
T5816 | 9603-9606 | VBD | denotes | was |
T5817 | 9584-9587 | DT | denotes | the |
T5818 | 9596-9602 | NN | denotes | number |
T5819 | 9588-9595 | VBN | denotes | reduced |
T5820 | 9607-9610 | IN | denotes | due |
T5821 | 9611-9613 | IN | denotes | to |
T5822 | 9614-9627 | JJ | denotes | intra-uterine |
T5823 | 9628-9634 | NN | denotes | demise |
T5824 | 9634-9635 | . | denotes | . |
T5825 | 9635-9836 | sentence | denotes | Litters were collected at E12.5, 13.5, 15.5, 17.5, and 18.5, and embryos were genotyped and evaluated for evidence of intra-uterine demise, including growth retardation, pallor, and tissue friability. |
T5826 | 9636-9643 | NNS | denotes | Litters |
T5827 | 9649-9658 | VBN | denotes | collected |
T5828 | 9644-9648 | VBD | denotes | were |
T5829 | 9659-9661 | IN | denotes | at |
T5830 | 9662-9667 | NN | denotes | E12.5 |
T5831 | 9667-9669 | , | denotes | , |
T5832 | 9669-9673 | CD | denotes | 13.5 |
T5833 | 9673-9675 | , | denotes | , |
T5834 | 9675-9679 | CD | denotes | 15.5 |
T5835 | 9679-9681 | , | denotes | , |
T5836 | 9681-9685 | CD | denotes | 17.5 |
T5837 | 9685-9687 | , | denotes | , |
T5838 | 9687-9690 | CC | denotes | and |
T5839 | 9691-9695 | CD | denotes | 18.5 |
T5840 | 9695-9697 | , | denotes | , |
T5841 | 9697-9700 | CC | denotes | and |
T5842 | 9701-9708 | NNS | denotes | embryos |
T5843 | 9714-9723 | VBN | denotes | genotyped |
T5844 | 9709-9713 | VBD | denotes | were |
T5845 | 9724-9727 | CC | denotes | and |
T5846 | 9728-9737 | VBN | denotes | evaluated |
T5847 | 9738-9741 | IN | denotes | for |
T5848 | 9742-9750 | NN | denotes | evidence |
T5849 | 9751-9753 | IN | denotes | of |
T5850 | 9754-9767 | JJ | denotes | intra-uterine |
T5851 | 9768-9774 | NN | denotes | demise |
T5852 | 9774-9776 | , | denotes | , |
T5853 | 9776-9785 | VBG | denotes | including |
T5854 | 9786-9792 | NN | denotes | growth |
T5855 | 9793-9804 | NN | denotes | retardation |
T5856 | 9804-9806 | , | denotes | , |
T5857 | 9806-9812 | NN | denotes | pallor |
T5858 | 9812-9814 | , | denotes | , |
T5859 | 9814-9817 | CC | denotes | and |
T5860 | 9818-9824 | NN | denotes | tissue |
T5861 | 9825-9835 | NN | denotes | friability |
T5862 | 9835-9836 | . | denotes | . |
T5863 | 9836-9915 | sentence | denotes | lil embryos had a progressively higher rate of demise between E13.5 and E15.5. |
T5864 | 9837-9840 | NN | denotes | lil |
T5865 | 9841-9848 | NNS | denotes | embryos |
T5866 | 9849-9852 | VBD | denotes | had |
T5867 | 9853-9854 | DT | denotes | a |
T5868 | 9876-9880 | NN | denotes | rate |
T1000 | 8-16 | VBN | denotes | Required |
T1001 | 5-7 | VBZ | denotes | Is |
T1002 | 17-20 | IN | denotes | for |
T1003 | 21-27 | JJ | denotes | Normal |
T1004 | 47-58 | NN | denotes | Development |
T1005 | 28-37 | NN | denotes | Diaphragm |
T1006 | 38-41 | CC | denotes | and |
T1007 | 42-46 | NN | denotes | Lung |
T1008 | 59-61 | IN | denotes | in |
T1009 | 62-66 | NNS | denotes | Mice |
T1010 | 67-70 | CC | denotes | and |
T1011 | 71-77 | NNS | denotes | Humans |
T1014 | 77-354 | sentence | denotes | Fog2 Required for Diaphragm and Lung Development Abstract Congenital diaphragmatic hernia and other congenital diaphragmatic defects are associated with significant mortality and morbidity in neonates; however, the molecular basis of these developmental anomalies is unknown. |
T1015 | 137-147 | JJ | denotes | Congenital |
T1016 | 162-168 | NN | denotes | hernia |
T1017 | 148-161 | JJ | denotes | diaphragmatic |
T1019 | 169-172 | CC | denotes | and |
T1020 | 173-178 | JJ | denotes | other |
T1021 | 204-211 | NNS | denotes | defects |
T1022 | 179-189 | JJ | denotes | congenital |
T1023 | 190-203 | JJ | denotes | diaphragmatic |
T1024 | 343-345 | VBZ | denotes | is |
T1025 | 216-226 | JJ | denotes | associated |
T1026 | 227-231 | IN | denotes | with |
T1027 | 232-243 | JJ | denotes | significant |
T1028 | 244-253 | NN | denotes | mortality |
T1029 | 254-257 | CC | denotes | and |
T1030 | 258-267 | NN | denotes | morbidity |
T1031 | 268-270 | IN | denotes | in |
T1032 | 271-279 | NNS | denotes | neonates |
T1033 | 279-280 | : | denotes | ; |
T1034 | 281-288 | RB | denotes | however |
T1035 | 288-290 | , | denotes | , |
T1036 | 290-293 | DT | denotes | the |
T1037 | 304-309 | NN | denotes | basis |
T1038 | 294-303 | JJ | denotes | molecular |
T1039 | 310-312 | IN | denotes | of |
T1040 | 313-318 | DT | denotes | these |
T1041 | 333-342 | NNS | denotes | anomalies |
T1042 | 319-332 | JJ | denotes | developmental |
T1043 | 346-353 | JJ | denotes | unknown |
T1044 | 353-354 | . | denotes | . |
T1045 | 354-538 | sentence | denotes | In an analysis of E18.5 embryos derived from mice treated with N-ethyl-N-nitrosourea, we identified a mutation that causes pulmonary hypoplasia and abnormal diaphragmatic development. |
T1046 | 355-357 | IN | denotes | In |
T1047 | 444-454 | VBD | denotes | identified |
T1048 | 358-360 | DT | denotes | an |
T1049 | 361-369 | NN | denotes | analysis |
T1050 | 370-372 | IN | denotes | of |
T1051 | 373-378 | NN | denotes | E18.5 |
T1052 | 379-386 | NNS | denotes | embryos |
T1053 | 387-394 | VBN | denotes | derived |
T1054 | 395-399 | IN | denotes | from |
T1055 | 400-404 | NNS | denotes | mice |
T1056 | 405-412 | VBN | denotes | treated |
T1057 | 413-417 | IN | denotes | with |
T1058 | 418-419 | NN | denotes | N |
T1059 | 420-425 | NN | denotes | ethyl |
T1060 | 419-420 | HYPH | denotes | - |
T1061 | 425-426 | HYPH | denotes | - |
T1062 | 426-427 | NN | denotes | N |
T1063 | 428-439 | NN | denotes | nitrosourea |
T1064 | 427-428 | HYPH | denotes | - |
T1065 | 439-441 | , | denotes | , |
T1066 | 441-443 | PRP | denotes | we |
T1067 | 455-456 | DT | denotes | a |
T1068 | 457-465 | NN | denotes | mutation |
T1069 | 466-470 | WDT | denotes | that |
T1070 | 471-477 | VBZ | denotes | causes |
T1071 | 478-487 | JJ | denotes | pulmonary |
T1072 | 488-498 | NN | denotes | hypoplasia |
T1073 | 499-502 | CC | denotes | and |
T1074 | 503-511 | JJ | denotes | abnormal |
T1075 | 526-537 | NN | denotes | development |
T1076 | 512-525 | JJ | denotes | diaphragmatic |
T1077 | 537-538 | . | denotes | . |
T1078 | 538-781 | sentence | denotes | Fog2 (Zfpm2) maps within the recombinant interval carrying the N-ethyl-N-nitrosourea-induced mutation, and DNA sequencing of Fog2 identified a mutation in a splice donor site that generates an abnormal transcript encoding a truncated protein. |
T1079 | 539-543 | NN | denotes | Fog2 |
T1080 | 552-556 | VBZ | denotes | maps |
T1081 | 544-545 | -LRB- | denotes | ( |
T1082 | 545-550 | NN | denotes | Zfpm2 |
T1083 | 550-551 | -RRB- | denotes | ) |
T1084 | 557-563 | IN | denotes | within |
T1085 | 564-567 | DT | denotes | the |
T1086 | 580-588 | NN | denotes | interval |
T1087 | 568-579 | JJ | denotes | recombinant |
T1088 | 589-597 | VBG | denotes | carrying |
T1089 | 598-601 | DT | denotes | the |
T1090 | 632-640 | NN | denotes | mutation |
T1091 | 602-603 | NN | denotes | N |
T1092 | 604-609 | NN | denotes | ethyl |
T1093 | 603-604 | HYPH | denotes | - |
T1094 | 624-631 | VBN | denotes | induced |
T1095 | 609-610 | HYPH | denotes | - |
T1096 | 610-611 | NN | denotes | N |
T1097 | 612-623 | NN | denotes | nitrosourea |
T1098 | 611-612 | HYPH | denotes | - |
T1099 | 623-624 | HYPH | denotes | - |
T1100 | 640-642 | , | denotes | , |
T1101 | 642-645 | CC | denotes | and |
T1102 | 646-649 | NN | denotes | DNA |
T1103 | 650-660 | NN | denotes | sequencing |
T1104 | 669-679 | VBD | denotes | identified |
T1105 | 661-663 | IN | denotes | of |
T1106 | 664-668 | NN | denotes | Fog2 |
T1107 | 680-681 | DT | denotes | a |
T1108 | 682-690 | NN | denotes | mutation |
T1109 | 691-693 | IN | denotes | in |
T1110 | 694-695 | DT | denotes | a |
T1111 | 709-713 | NN | denotes | site |
T1112 | 696-702 | NN | denotes | splice |
T1113 | 703-708 | NN | denotes | donor |
T1114 | 714-718 | WDT | denotes | that |
T1115 | 719-728 | VBZ | denotes | generates |
T1116 | 729-731 | DT | denotes | an |
T1117 | 741-751 | NN | denotes | transcript |
T1118 | 732-740 | JJ | denotes | abnormal |
T1119 | 752-760 | VBG | denotes | encoding |
T1120 | 761-762 | DT | denotes | a |
T1121 | 773-780 | NN | denotes | protein |
T1122 | 763-772 | VBN | denotes | truncated |
T1123 | 780-781 | . | denotes | . |
T1124 | 781-890 | sentence | denotes | Human autopsy cases with diaphragmatic defect and pulmonary hypoplasia were evaluated for mutations in FOG2. |
T1125 | 782-787 | JJ | denotes | Human |
T1126 | 796-801 | NNS | denotes | cases |
T1127 | 788-795 | NN | denotes | autopsy |
T1128 | 858-867 | VBN | denotes | evaluated |
T1129 | 802-806 | IN | denotes | with |
T1130 | 807-820 | JJ | denotes | diaphragmatic |
T1131 | 821-827 | NN | denotes | defect |
T1132 | 828-831 | CC | denotes | and |
T1133 | 832-841 | JJ | denotes | pulmonary |
T1134 | 842-852 | NN | denotes | hypoplasia |
T1135 | 853-857 | VBD | denotes | were |
T1136 | 868-871 | IN | denotes | for |
T1137 | 872-881 | NNS | denotes | mutations |
T1138 | 882-884 | IN | denotes | in |
T1139 | 885-889 | NN | denotes | FOG2 |
T1140 | 889-890 | . | denotes | . |
T1141 | 890-1110 | sentence | denotes | Sequence analysis revealed a de novo mutation resulting in a premature stop codon in a child who died on the first day of life secondary to severe bilateral pulmonary hypoplasia and an abnormally muscularized diaphragm. |
T1142 | 891-899 | NN | denotes | Sequence |
T1143 | 900-908 | NN | denotes | analysis |
T1144 | 909-917 | VBD | denotes | revealed |
T1145 | 918-919 | DT | denotes | a |
T1146 | 928-936 | NN | denotes | mutation |
T1147 | 920-922 | FW | denotes | de |
T1148 | 923-927 | FW | denotes | novo |
T1149 | 937-946 | VBG | denotes | resulting |
T1150 | 947-949 | IN | denotes | in |
T1151 | 950-951 | DT | denotes | a |
T1152 | 967-972 | NN | denotes | codon |
T1153 | 952-961 | JJ | denotes | premature |
T1154 | 962-966 | NN | denotes | stop |
T1155 | 973-975 | IN | denotes | in |
T1156 | 976-977 | DT | denotes | a |
T1157 | 978-983 | NN | denotes | child |
T1158 | 984-987 | WP | denotes | who |
T1159 | 988-992 | VBD | denotes | died |
T1160 | 993-995 | IN | denotes | on |
T1161 | 996-999 | DT | denotes | the |
T1162 | 1006-1009 | NN | denotes | day |
T1163 | 1000-1005 | JJ | denotes | first |
T1164 | 1010-1012 | IN | denotes | of |
T1165 | 1013-1017 | NN | denotes | life |
T1166 | 1018-1027 | JJ | denotes | secondary |
T1167 | 1028-1030 | IN | denotes | to |
T1168 | 1031-1037 | JJ | denotes | severe |
T1169 | 1058-1068 | NN | denotes | hypoplasia |
T1170 | 1038-1047 | JJ | denotes | bilateral |
T1171 | 1048-1057 | JJ | denotes | pulmonary |
T1172 | 1069-1072 | CC | denotes | and |
T1173 | 1073-1075 | DT | denotes | an |
T1174 | 1100-1109 | NN | denotes | diaphragm |
T1175 | 1076-1086 | RB | denotes | abnormally |
T1176 | 1087-1099 | VBN | denotes | muscularized |
T1177 | 1109-1110 | . | denotes | . |
T1178 | 1110-1279 | sentence | denotes | Using a phenotype-driven approach, we have established that Fog2 is required for normal diaphragm and lung development, a role that has not been previously appreciated. |
T1179 | 1111-1116 | VBG | denotes | Using |
T1180 | 1154-1165 | VBN | denotes | established |
T1181 | 1117-1118 | DT | denotes | a |
T1182 | 1136-1144 | NN | denotes | approach |
T1183 | 1119-1128 | NN | denotes | phenotype |
T1184 | 1129-1135 | VBN | denotes | driven |
T1185 | 1128-1129 | HYPH | denotes | - |
T1186 | 1144-1146 | , | denotes | , |
T1187 | 1146-1148 | PRP | denotes | we |
T1188 | 1149-1153 | VBP | denotes | have |
T1189 | 1166-1170 | IN | denotes | that |
T1190 | 1179-1187 | VBN | denotes | required |
T1191 | 1171-1175 | NN | denotes | Fog2 |
T1192 | 1176-1178 | VBZ | denotes | is |
T1193 | 1188-1191 | IN | denotes | for |
T1194 | 1192-1198 | JJ | denotes | normal |
T1195 | 1218-1229 | NN | denotes | development |
T1196 | 1199-1208 | NN | denotes | diaphragm |
T1197 | 1209-1212 | CC | denotes | and |
T1198 | 1213-1217 | NN | denotes | lung |
T1199 | 1229-1231 | , | denotes | , |
T1200 | 1231-1232 | DT | denotes | a |
T1201 | 1233-1237 | NN | denotes | role |
T1202 | 1238-1242 | WDT | denotes | that |
T1203 | 1267-1278 | VBN | denotes | appreciated |
T1204 | 1243-1246 | VBZ | denotes | has |
T1205 | 1247-1250 | RB | denotes | not |
T1206 | 1251-1255 | VBN | denotes | been |
T1207 | 1256-1266 | RB | denotes | previously |
T1208 | 1278-1279 | . | denotes | . |
T1209 | 1279-1570 | sentence | denotes | FOG2 is the first gene implicated in the pathogenesis of nonsyndromic human congenital diaphragmatic defects, and its necessity for pulmonary development validates the hypothesis that neonates with congenital diaphragmatic hernia may also have primary pulmonary developmental abnormalities. |
T1210 | 1280-1284 | NN | denotes | FOG2 |
T1211 | 1285-1287 | VBZ | denotes | is |
T1212 | 1288-1291 | DT | denotes | the |
T1213 | 1298-1302 | NN | denotes | gene |
T1214 | 1292-1297 | JJ | denotes | first |
T1215 | 1303-1313 | VBN | denotes | implicated |
T1216 | 1314-1316 | IN | denotes | in |
T1217 | 1317-1320 | DT | denotes | the |
T1218 | 1321-1333 | NN | denotes | pathogenesis |
T1219 | 1334-1336 | IN | denotes | of |
T1220 | 1337-1349 | JJ | denotes | nonsyndromic |
T1221 | 1381-1388 | NNS | denotes | defects |
T1222 | 1350-1355 | JJ | denotes | human |
T1223 | 1356-1366 | JJ | denotes | congenital |
T1224 | 1367-1380 | JJ | denotes | diaphragmatic |
T1225 | 1388-1390 | , | denotes | , |
T1226 | 1390-1393 | CC | denotes | and |
T1227 | 1394-1397 | PRP$ | denotes | its |
T1228 | 1398-1407 | NN | denotes | necessity |
T1229 | 1434-1443 | VBZ | denotes | validates |
T1230 | 1408-1411 | IN | denotes | for |
T1231 | 1412-1421 | JJ | denotes | pulmonary |
T1232 | 1422-1433 | NN | denotes | development |
T1233 | 1444-1447 | DT | denotes | the |
T1234 | 1448-1458 | NN | denotes | hypothesis |
T1235 | 1459-1463 | IN | denotes | that |
T1236 | 1519-1523 | VB | denotes | have |
T1237 | 1464-1472 | NNS | denotes | neonates |
T1238 | 1473-1477 | IN | denotes | with |
T1239 | 1478-1488 | JJ | denotes | congenital |
T1240 | 1503-1509 | NN | denotes | hernia |
T1241 | 1489-1502 | JJ | denotes | diaphragmatic |
T1242 | 1510-1513 | MD | denotes | may |
T1243 | 1514-1518 | RB | denotes | also |
T1244 | 1524-1531 | JJ | denotes | primary |
T1245 | 1556-1569 | NNS | denotes | abnormalities |
T1246 | 1532-1541 | JJ | denotes | pulmonary |
T1247 | 1542-1555 | JJ | denotes | developmental |
T1248 | 1569-1570 | . | denotes | . |
T2580 | 3027-3037 | JJ | denotes | Congenital |
T2581 | 3052-3059 | NNS | denotes | defects |
T2582 | 3038-3051 | JJ | denotes | diaphragmatic |
T2583 | 3060-3063 | VBP | denotes | are |
T2584 | 3064-3065 | DT | denotes | a |
T2585 | 3066-3074 | NN | denotes | spectrum |
T2586 | 3075-3077 | IN | denotes | of |
T2587 | 3078-3088 | RB | denotes | relatively |
T2588 | 3089-3095 | JJ | denotes | common |
T2589 | 3102-3109 | NNS | denotes | defects |
T2590 | 3096-3101 | NN | denotes | birth |
T2591 | 3109-3110 | . | denotes | . |
T2592 | 3110-3455 | sentence | denotes | The Bochdalek or posterolateral hernias (often referred to as congenital diaphragmatic hernia [CDH]) occur in 1/3,000 live births [1], and although these are the most common type of diaphragmatic defect presenting at birth, diaphragmatic aplasia and diaphragmatic muscularization defects (eventrations) may have a similar clinical presentation. |
T2593 | 3111-3114 | DT | denotes | The |
T2594 | 3115-3124 | NNP | denotes | Bochdalek |
T2595 | 3212-3217 | VBP | denotes | occur |
T2596 | 3125-3127 | CC | denotes | or |
T2597 | 3128-3142 | JJ | denotes | posterolateral |
T2598 | 3143-3150 | NNS | denotes | hernias |
T2599 | 3151-3152 | -LRB- | denotes | ( |
T2600 | 3152-3157 | RB | denotes | often |
T2601 | 3158-3166 | VBN | denotes | referred |
T2602 | 3167-3169 | IN | denotes | to |
T2603 | 3170-3172 | IN | denotes | as |
T2604 | 3173-3183 | JJ | denotes | congenital |
T2605 | 3198-3204 | NN | denotes | hernia |
T2606 | 3184-3197 | JJ | denotes | diaphragmatic |
T2607 | 3205-3206 | -LRB- | denotes | [ |
T2608 | 3206-3209 | NN | denotes | CDH |
T2609 | 3209-3210 | -RRB- | denotes | ] |
T2610 | 3210-3211 | -RRB- | denotes | ) |
T2611 | 3218-3220 | IN | denotes | in |
T2612 | 3221-3222 | CD | denotes | 1 |
T2613 | 3223-3228 | CD | denotes | 3,000 |
T2614 | 3222-3223 | SYM | denotes | / |
T2615 | 3234-3240 | NNS | denotes | births |
T2616 | 3229-3233 | JJ | denotes | live |
T2617 | 3241-3242 | -LRB- | denotes | [ |
T2618 | 3242-3243 | CD | denotes | 1 |
T2619 | 3243-3244 | -RRB- | denotes | ] |
T2620 | 3244-3246 | , | denotes | , |
T2621 | 3246-3249 | CC | denotes | and |
T2622 | 3250-3258 | IN | denotes | although |
T2623 | 3265-3268 | VBP | denotes | are |
T2624 | 3259-3264 | DT | denotes | these |
T2625 | 3418-3422 | VB | denotes | have |
T2626 | 3269-3272 | DT | denotes | the |
T2627 | 3285-3289 | NN | denotes | type |
T2628 | 3273-3277 | RBS | denotes | most |
T2629 | 3278-3284 | JJ | denotes | common |
T2630 | 3290-3292 | IN | denotes | of |
T2631 | 3293-3306 | JJ | denotes | diaphragmatic |
T2632 | 3307-3313 | NN | denotes | defect |
T2633 | 3314-3324 | VBG | denotes | presenting |
T2634 | 3325-3327 | IN | denotes | at |
T2635 | 3328-3333 | NN | denotes | birth |
T2636 | 3333-3335 | , | denotes | , |
T2637 | 3335-3348 | JJ | denotes | diaphragmatic |
T2638 | 3349-3356 | NN | denotes | aplasia |
T2639 | 3357-3360 | CC | denotes | and |
T2640 | 3361-3374 | JJ | denotes | diaphragmatic |
T2641 | 3391-3398 | NNS | denotes | defects |
T2642 | 3375-3390 | NN | denotes | muscularization |
T2643 | 3399-3400 | -LRB- | denotes | ( |
T2644 | 3400-3412 | NNS | denotes | eventrations |
T2645 | 3412-3413 | -RRB- | denotes | ) |
T2646 | 3414-3417 | MD | denotes | may |
T2647 | 3423-3424 | DT | denotes | a |
T2648 | 3442-3454 | NN | denotes | presentation |
T2649 | 3425-3432 | JJ | denotes | similar |
T2650 | 3433-3441 | JJ | denotes | clinical |
T2651 | 3454-3455 | . | denotes | . |
T2652 | 3455-3604 | sentence | denotes | Making specific anatomic distinctions among these types of defects can be difficult without direct gross (intraoperative or postmortem) examination. |
T2653 | 3456-3462 | VBG | denotes | Making |
T2654 | 3527-3529 | VB | denotes | be |
T2655 | 3463-3471 | JJ | denotes | specific |
T2656 | 3481-3493 | NNS | denotes | distinctions |
T2657 | 3472-3480 | JJ | denotes | anatomic |
T2658 | 3494-3499 | IN | denotes | among |
T2659 | 3500-3505 | DT | denotes | these |
T2660 | 3506-3511 | NNS | denotes | types |
T2661 | 3512-3514 | IN | denotes | of |
T2662 | 3515-3522 | NNS | denotes | defects |
T2663 | 3523-3526 | MD | denotes | can |
T2664 | 3530-3539 | JJ | denotes | difficult |
T2665 | 3540-3547 | IN | denotes | without |
T2666 | 3548-3554 | JJ | denotes | direct |
T2667 | 3592-3603 | NN | denotes | examination |
T2668 | 3555-3560 | JJ | denotes | gross |
T2669 | 3561-3562 | -LRB- | denotes | ( |
T2670 | 3562-3576 | JJ | denotes | intraoperative |
T2671 | 3577-3579 | CC | denotes | or |
T2672 | 3580-3590 | JJ | denotes | postmortem |
T2673 | 3590-3591 | -RRB- | denotes | ) |
T2674 | 3603-3604 | . | denotes | . |
T2675 | 3604-3708 | sentence | denotes | Pulmonary hypoplasia associated with these diaphragmatic defects causes severe mortality and morbidity. |
T2676 | 3605-3614 | JJ | denotes | Pulmonary |
T2677 | 3615-3625 | NN | denotes | hypoplasia |
T2678 | 3670-3676 | VBZ | denotes | causes |
T2679 | 3626-3636 | JJ | denotes | associated |
T2680 | 3637-3641 | IN | denotes | with |
T2681 | 3642-3647 | DT | denotes | these |
T2682 | 3662-3669 | NNS | denotes | defects |
T2683 | 3648-3661 | JJ | denotes | diaphragmatic |
T2684 | 3677-3683 | JJ | denotes | severe |
T2685 | 3684-3693 | NN | denotes | mortality |
T2686 | 3694-3697 | CC | denotes | and |
T2687 | 3698-3707 | NN | denotes | morbidity |
T2688 | 3707-3708 | . | denotes | . |
T2689 | 3708-3830 | sentence | denotes | The pathogenesis and developmental relationship between diaphragmatic defects and pulmonary hypoplasia is not understood. |
T2690 | 3709-3712 | DT | denotes | The |
T2691 | 3713-3725 | NN | denotes | pathogenesis |
T2692 | 3819-3829 | VBN | denotes | understood |
T2693 | 3726-3729 | CC | denotes | and |
T2694 | 3730-3743 | JJ | denotes | developmental |
T2695 | 3744-3756 | NN | denotes | relationship |
T2696 | 3757-3764 | IN | denotes | between |
T2697 | 3765-3778 | JJ | denotes | diaphragmatic |
T2698 | 3779-3786 | NNS | denotes | defects |
T2699 | 3787-3790 | CC | denotes | and |
T2700 | 3791-3800 | JJ | denotes | pulmonary |
T2701 | 3801-3811 | NN | denotes | hypoplasia |
T2702 | 3812-3814 | VBZ | denotes | is |
T2703 | 3815-3818 | RB | denotes | not |
T2704 | 3829-3830 | . | denotes | . |
T2705 | 3830-4192 | sentence | denotes | Although advances in the medical management of pulmonary hypoplasia may have decreased the mortality associated with CDH patients who survive to receive care at high-volume centers [2,3], the population-based mortality has been reported to be as great as 62%, and there are a large number of deaths prior to birth or to transfer to a tertiary care facility [4]. |
T2706 | 3831-3839 | IN | denotes | Although |
T2707 | 3908-3917 | VBN | denotes | decreased |
T2708 | 3840-3848 | NNS | denotes | advances |
T2709 | 3849-3851 | IN | denotes | in |
T2710 | 3852-3855 | DT | denotes | the |
T2711 | 3864-3874 | NN | denotes | management |
T2712 | 3856-3863 | JJ | denotes | medical |
T2713 | 3875-3877 | IN | denotes | of |
T2714 | 3878-3887 | JJ | denotes | pulmonary |
T2715 | 3888-3898 | NN | denotes | hypoplasia |
T2716 | 3899-3902 | MD | denotes | may |
T2717 | 3903-3907 | VB | denotes | have |
T2718 | 4059-4067 | VBN | denotes | reported |
T2719 | 3918-3921 | DT | denotes | the |
T2720 | 3922-3931 | NN | denotes | mortality |
T2721 | 3932-3942 | JJ | denotes | associated |
T2722 | 3943-3947 | IN | denotes | with |
T2723 | 3948-3951 | NN | denotes | CDH |
T2724 | 3952-3960 | NNS | denotes | patients |
T2725 | 3961-3964 | WP | denotes | who |
T2726 | 3965-3972 | VBP | denotes | survive |
T2727 | 3973-3975 | TO | denotes | to |
T2728 | 3976-3983 | VB | denotes | receive |
T2729 | 3984-3988 | NN | denotes | care |
T2730 | 3989-3991 | IN | denotes | at |
T2731 | 3992-3996 | JJ | denotes | high |
T2732 | 3997-4003 | NN | denotes | volume |
T2733 | 3996-3997 | HYPH | denotes | - |
T2734 | 4004-4011 | NNS | denotes | centers |
T2735 | 4012-4013 | -LRB- | denotes | [ |
T2736 | 4015-4016 | CD | denotes | 3 |
T2737 | 4013-4014 | CD | denotes | 2 |
T2738 | 4014-4015 | , | denotes | , |
T2739 | 4016-4017 | -RRB- | denotes | ] |
T2740 | 4017-4019 | , | denotes | , |
T2741 | 4019-4022 | DT | denotes | the |
T2742 | 4040-4049 | NN | denotes | mortality |
T2743 | 4023-4033 | NN | denotes | population |
T2744 | 4034-4039 | VBN | denotes | based |
T2745 | 4033-4034 | HYPH | denotes | - |
T2746 | 4050-4053 | VBZ | denotes | has |
T2747 | 4054-4058 | VBN | denotes | been |
T2748 | 4068-4070 | TO | denotes | to |
T2749 | 4071-4073 | VB | denotes | be |
T2750 | 4074-4076 | RB | denotes | as |
T2751 | 4086-4088 | CD | denotes | 62 |
T2752 | 4077-4082 | JJ | denotes | great |
T2753 | 4083-4085 | IN | denotes | as |
T2754 | 4088-4089 | NN | denotes | % |
T2755 | 4089-4091 | , | denotes | , |
T2756 | 4091-4094 | CC | denotes | and |
T2757 | 4095-4100 | EX | denotes | there |
T2758 | 4101-4104 | VBP | denotes | are |
T2759 | 4105-4106 | DT | denotes | a |
T2760 | 4113-4119 | NN | denotes | number |
T2761 | 4107-4112 | JJ | denotes | large |
T2762 | 4120-4122 | IN | denotes | of |
T2763 | 4123-4129 | NNS | denotes | deaths |
T2764 | 4130-4135 | JJ | denotes | prior |
T2765 | 4136-4138 | IN | denotes | to |
T2766 | 4139-4144 | NN | denotes | birth |
T2767 | 4145-4147 | CC | denotes | or |
T2768 | 4148-4150 | IN | denotes | to |
T2769 | 4151-4159 | NN | denotes | transfer |
T2770 | 4160-4162 | IN | denotes | to |
T2771 | 4163-4164 | DT | denotes | a |
T2772 | 4179-4187 | NN | denotes | facility |
T2773 | 4165-4173 | JJ | denotes | tertiary |
T2774 | 4174-4178 | NN | denotes | care |
T2775 | 4188-4189 | -LRB- | denotes | [ |
T2776 | 4189-4190 | CD | denotes | 4 |
T2777 | 4190-4191 | -RRB- | denotes | ] |
T2778 | 4191-4192 | . | denotes | . |
T2779 | 4192-4400 | sentence | denotes | As these patients commonly present with severe respiratory failure at birth, therapy has been centered around developing better methods to provide ventilatory support while not producing further lung injury. |
T2780 | 4193-4195 | IN | denotes | As |
T2781 | 4220-4227 | VBP | denotes | present |
T2782 | 4196-4201 | DT | denotes | these |
T2783 | 4202-4210 | NNS | denotes | patients |
T2784 | 4211-4219 | RB | denotes | commonly |
T2785 | 4287-4295 | VBN | denotes | centered |
T2786 | 4228-4232 | IN | denotes | with |
T2787 | 4233-4239 | JJ | denotes | severe |
T2788 | 4252-4259 | NN | denotes | failure |
T2789 | 4240-4251 | JJ | denotes | respiratory |
T2790 | 4260-4262 | IN | denotes | at |
T2791 | 4263-4268 | NN | denotes | birth |
T2792 | 4268-4270 | , | denotes | , |
T2793 | 4270-4277 | NN | denotes | therapy |
T2794 | 4278-4281 | VBZ | denotes | has |
T2795 | 4282-4286 | VBN | denotes | been |
T2796 | 4296-4302 | IN | denotes | around |
T2797 | 4303-4313 | VBG | denotes | developing |
T2798 | 4314-4320 | JJR | denotes | better |
T2799 | 4321-4328 | NNS | denotes | methods |
T2800 | 4329-4331 | TO | denotes | to |
T2801 | 4332-4339 | VB | denotes | provide |
T2802 | 4340-4351 | JJ | denotes | ventilatory |
T2803 | 4352-4359 | NN | denotes | support |
T2804 | 4360-4365 | IN | denotes | while |
T2805 | 4370-4379 | VBG | denotes | producing |
T2806 | 4366-4369 | RB | denotes | not |
T2807 | 4380-4387 | JJ | denotes | further |
T2808 | 4393-4399 | NN | denotes | injury |
T2809 | 4388-4392 | NN | denotes | lung |
T2810 | 4399-4400 | . | denotes | . |
T2811 | 4400-4611 | sentence | denotes | Extracorporeal membrane oxygenation (ECMO) is used in some centers to provide an extended period of cardiopulmonary bypass [5,6], while other centers have success using other ventilatory support techniques [7]. |
T2812 | 4401-4415 | JJ | denotes | Extracorporeal |
T2813 | 4425-4436 | NN | denotes | oxygenation |
T2814 | 4416-4424 | NN | denotes | membrane |
T2815 | 4447-4451 | VBN | denotes | used |
T2816 | 4437-4438 | -LRB- | denotes | ( |
T2817 | 4438-4442 | NN | denotes | ECMO |
T2818 | 4442-4443 | -RRB- | denotes | ) |
T2819 | 4444-4446 | VBZ | denotes | is |
T2820 | 4452-4454 | IN | denotes | in |
T2821 | 4455-4459 | DT | denotes | some |
T2822 | 4460-4467 | NNS | denotes | centers |
T2823 | 4468-4470 | TO | denotes | to |
T2824 | 4471-4478 | VB | denotes | provide |
T2825 | 4479-4481 | DT | denotes | an |
T2826 | 4491-4497 | NN | denotes | period |
T2827 | 4482-4490 | JJ | denotes | extended |
T2828 | 4498-4500 | IN | denotes | of |
T2829 | 4501-4516 | JJ | denotes | cardiopulmonary |
T2830 | 4517-4523 | NN | denotes | bypass |
T2831 | 4524-4525 | -LRB- | denotes | [ |
T2832 | 4527-4528 | CD | denotes | 6 |
T2833 | 4525-4526 | CD | denotes | 5 |
T2834 | 4526-4527 | , | denotes | , |
T2835 | 4528-4529 | -RRB- | denotes | ] |
T2836 | 4529-4531 | , | denotes | , |
T2837 | 4531-4536 | IN | denotes | while |
T2838 | 4551-4555 | VBP | denotes | have |
T2839 | 4537-4542 | JJ | denotes | other |
T2840 | 4543-4550 | NNS | denotes | centers |
T2841 | 4556-4563 | NN | denotes | success |
T2842 | 4564-4569 | VBG | denotes | using |
T2843 | 4570-4575 | JJ | denotes | other |
T2844 | 4596-4606 | NNS | denotes | techniques |
T2845 | 4576-4587 | JJ | denotes | ventilatory |
T2846 | 4588-4595 | NN | denotes | support |
T2847 | 4607-4608 | -LRB- | denotes | [ |
T2848 | 4608-4609 | CD | denotes | 7 |
T2849 | 4609-4610 | -RRB- | denotes | ] |
T2850 | 4610-4611 | . | denotes | . |
T2851 | 4611-4901 | sentence | denotes | The morbidity in those who survive is high, and many patients survive with chronic respiratory insufficiency, cognitive and neuromotor deficits, and hearing loss as a result of necessary intensive interventions and associated structural and irreversible developmental abnormalities [8–11]. |
T2852 | 4612-4615 | DT | denotes | The |
T2853 | 4616-4625 | NN | denotes | morbidity |
T2854 | 4647-4649 | VBZ | denotes | is |
T2855 | 4626-4628 | IN | denotes | in |
T2856 | 4629-4634 | DT | denotes | those |
T2857 | 4635-4638 | WP | denotes | who |
T2858 | 4639-4646 | VBP | denotes | survive |
T2859 | 4650-4654 | JJ | denotes | high |
T2860 | 4654-4656 | , | denotes | , |
T2861 | 4656-4659 | CC | denotes | and |
T2862 | 4660-4664 | JJ | denotes | many |
T2863 | 4665-4673 | NNS | denotes | patients |
T2864 | 4674-4681 | VBP | denotes | survive |
T2865 | 4682-4686 | IN | denotes | with |
T2866 | 4687-4694 | JJ | denotes | chronic |
T2867 | 4707-4720 | NN | denotes | insufficiency |
T2868 | 4695-4706 | JJ | denotes | respiratory |
T2869 | 4720-4722 | , | denotes | , |
T2870 | 4722-4731 | JJ | denotes | cognitive |
T2871 | 4747-4755 | NNS | denotes | deficits |
T2872 | 4732-4735 | CC | denotes | and |
T2873 | 4736-4746 | JJ | denotes | neuromotor |
T2874 | 4755-4757 | , | denotes | , |
T2875 | 4757-4760 | CC | denotes | and |
T2876 | 4761-4768 | NN | denotes | hearing |
T2877 | 4769-4773 | NN | denotes | loss |
T2878 | 4774-4776 | IN | denotes | as |
T2879 | 4777-4778 | DT | denotes | a |
T2880 | 4779-4785 | NN | denotes | result |
T2881 | 4786-4788 | IN | denotes | of |
T2882 | 4789-4798 | JJ | denotes | necessary |
T2883 | 4809-4822 | NNS | denotes | interventions |
T2884 | 4799-4808 | JJ | denotes | intensive |
T2885 | 4823-4826 | CC | denotes | and |
T2886 | 4827-4837 | VBN | denotes | associated |
T2887 | 4880-4893 | NNS | denotes | abnormalities |
T2888 | 4838-4848 | JJ | denotes | structural |
T2889 | 4849-4852 | CC | denotes | and |
T2890 | 4853-4865 | JJ | denotes | irreversible |
T2891 | 4866-4879 | JJ | denotes | developmental |
T2892 | 4894-4895 | -LRB- | denotes | [ |
T2893 | 4895-4896 | CD | denotes | 8 |
T2894 | 4896-4897 | SYM | denotes | – |
T2895 | 4897-4899 | CD | denotes | 11 |
T2896 | 4899-4900 | -RRB- | denotes | ] |
T2897 | 4900-4901 | . | denotes | . |
T2898 | 4901-5047 | sentence | denotes | To date, there have been no specific mutations found to be associated with nonsyndromic diaphragmatic defects and pulmonary hypoplasia in humans. |
T2899 | 4902-4904 | IN | denotes | To |
T2900 | 4922-4926 | VBN | denotes | been |
T2901 | 4905-4909 | NN | denotes | date |
T2902 | 4909-4911 | , | denotes | , |
T2903 | 4911-4916 | EX | denotes | there |
T2904 | 4917-4921 | VBP | denotes | have |
T2905 | 4927-4929 | DT | denotes | no |
T2906 | 4939-4948 | NNS | denotes | mutations |
T2907 | 4930-4938 | JJ | denotes | specific |
T2908 | 4949-4954 | VBN | denotes | found |
T2909 | 4955-4957 | TO | denotes | to |
T2910 | 4958-4960 | VB | denotes | be |
T2911 | 4961-4971 | JJ | denotes | associated |
T2912 | 4972-4976 | IN | denotes | with |
T2913 | 4977-4989 | JJ | denotes | nonsyndromic |
T2914 | 5004-5011 | NNS | denotes | defects |
T2915 | 4990-5003 | JJ | denotes | diaphragmatic |
T2916 | 5012-5015 | CC | denotes | and |
T2917 | 5016-5025 | JJ | denotes | pulmonary |
T2918 | 5026-5036 | NN | denotes | hypoplasia |
T2919 | 5037-5039 | IN | denotes | in |
T2920 | 5040-5046 | NNS | denotes | humans |
T2921 | 5046-5047 | . | denotes | . |
T2922 | 5047-5194 | sentence | denotes | The heritability of these defects is unclear, as the high morbidity and mortality limit the collection of multigenerational families for analysis. |
T2923 | 5048-5051 | DT | denotes | The |
T2924 | 5052-5064 | NN | denotes | heritability |
T2925 | 5082-5084 | VBZ | denotes | is |
T2926 | 5065-5067 | IN | denotes | of |
T2927 | 5068-5073 | DT | denotes | these |
T2928 | 5074-5081 | NNS | denotes | defects |
T2929 | 5085-5092 | JJ | denotes | unclear |
T2930 | 5092-5094 | , | denotes | , |
T2931 | 5094-5096 | IN | denotes | as |
T2932 | 5130-5135 | VBP | denotes | limit |
T2933 | 5097-5100 | DT | denotes | the |
T2934 | 5106-5115 | NN | denotes | morbidity |
T2935 | 5101-5105 | JJ | denotes | high |
T2936 | 5116-5119 | CC | denotes | and |
T2937 | 5120-5129 | NN | denotes | mortality |
T2938 | 5136-5139 | DT | denotes | the |
T2939 | 5140-5150 | NN | denotes | collection |
T2940 | 5151-5153 | IN | denotes | of |
T2941 | 5154-5171 | JJ | denotes | multigenerational |
T2942 | 5172-5180 | NNS | denotes | families |
T2943 | 5181-5184 | IN | denotes | for |
T2944 | 5185-5193 | NN | denotes | analysis |
T2945 | 5193-5194 | . | denotes | . |
T2946 | 5194-5383 | sentence | denotes | The genetic etiologies are likely to be complex and probably arise from different mutations in various parts of the molecular developmental pathways required for diaphragmatic development. |
T2947 | 5195-5198 | DT | denotes | The |
T2948 | 5207-5217 | NNS | denotes | etiologies |
T2949 | 5199-5206 | JJ | denotes | genetic |
T2950 | 5218-5221 | VBP | denotes | are |
T2951 | 5222-5228 | JJ | denotes | likely |
T2952 | 5229-5231 | TO | denotes | to |
T2953 | 5232-5234 | VB | denotes | be |
T2954 | 5235-5242 | JJ | denotes | complex |
T2955 | 5243-5246 | CC | denotes | and |
T2956 | 5247-5255 | RB | denotes | probably |
T2957 | 5256-5261 | VBP | denotes | arise |
T2958 | 5262-5266 | IN | denotes | from |
T2959 | 5267-5276 | JJ | denotes | different |
T2960 | 5277-5286 | NNS | denotes | mutations |
T2961 | 5287-5289 | IN | denotes | in |
T2962 | 5290-5297 | JJ | denotes | various |
T2963 | 5298-5303 | NNS | denotes | parts |
T2964 | 5304-5306 | IN | denotes | of |
T2965 | 5307-5310 | DT | denotes | the |
T2966 | 5335-5343 | NNS | denotes | pathways |
T2967 | 5311-5320 | JJ | denotes | molecular |
T2968 | 5321-5334 | JJ | denotes | developmental |
T2969 | 5344-5352 | VBN | denotes | required |
T2970 | 5353-5356 | IN | denotes | for |
T2971 | 5357-5370 | JJ | denotes | diaphragmatic |
T2972 | 5371-5382 | NN | denotes | development |
T2973 | 5382-5383 | . | denotes | . |
T2974 | 5383-5502 | sentence | denotes | Indeed, there are numerous reports implicating different chromosomal abnormalities in the pathogenesis of CDH [12,13]. |
T2975 | 5384-5390 | RB | denotes | Indeed |
T2976 | 5398-5401 | VBP | denotes | are |
T2977 | 5390-5392 | , | denotes | , |
T2978 | 5392-5397 | EX | denotes | there |
T2979 | 5402-5410 | JJ | denotes | numerous |
T2980 | 5411-5418 | NNS | denotes | reports |
T2981 | 5419-5430 | VBG | denotes | implicating |
T2982 | 5431-5440 | JJ | denotes | different |
T2983 | 5453-5466 | NNS | denotes | abnormalities |
T2984 | 5441-5452 | JJ | denotes | chromosomal |
T2985 | 5467-5469 | IN | denotes | in |
T2986 | 5470-5473 | DT | denotes | the |
T2987 | 5474-5486 | NN | denotes | pathogenesis |
T2988 | 5487-5489 | IN | denotes | of |
T2989 | 5490-5493 | NN | denotes | CDH |
T2990 | 5494-5495 | -LRB- | denotes | [ |
T2991 | 5498-5500 | CD | denotes | 13 |
T2992 | 5495-5497 | CD | denotes | 12 |
T2993 | 5497-5498 | , | denotes | , |
T2994 | 5500-5501 | -RRB- | denotes | ] |
T2995 | 5501-5502 | . | denotes | . |
T2996 | 5502-5771 | sentence | denotes | Given the difficulty of studying lethal developmental abnormalities in humans, it is of great potential utility to develop animal models of human birth defects, as the specific genetic abnormalities found in animal models can then be investigated in human populations. |
T2997 | 5503-5508 | VBN | denotes | Given |
T2998 | 5585-5587 | VBZ | denotes | is |
T2999 | 5509-5512 | DT | denotes | the |
T3000 | 5513-5523 | NN | denotes | difficulty |
T3001 | 5524-5526 | IN | denotes | of |
T3002 | 5527-5535 | VBG | denotes | studying |
T3003 | 5536-5542 | JJ | denotes | lethal |
T3004 | 5557-5570 | NNS | denotes | abnormalities |
T3005 | 5543-5556 | JJ | denotes | developmental |
T3006 | 5571-5573 | IN | denotes | in |
T3007 | 5574-5580 | NNS | denotes | humans |
T3008 | 5580-5582 | , | denotes | , |
T3009 | 5582-5584 | PRP | denotes | it |
T3010 | 5588-5590 | IN | denotes | of |
T3011 | 5591-5596 | JJ | denotes | great |
T3012 | 5607-5614 | NN | denotes | utility |
T3013 | 5597-5606 | JJ | denotes | potential |
T3014 | 5615-5617 | TO | denotes | to |
T3015 | 5618-5625 | VB | denotes | develop |
T3016 | 5626-5632 | NN | denotes | animal |
T3017 | 5633-5639 | NNS | denotes | models |
T3018 | 5640-5642 | IN | denotes | of |
T3019 | 5643-5648 | JJ | denotes | human |
T3020 | 5655-5662 | NNS | denotes | defects |
T3021 | 5649-5654 | NN | denotes | birth |
T3022 | 5662-5664 | , | denotes | , |
T3023 | 5664-5666 | IN | denotes | as |
T3024 | 5737-5749 | VBN | denotes | investigated |
T3025 | 5667-5670 | DT | denotes | the |
T3026 | 5688-5701 | NNS | denotes | abnormalities |
T3027 | 5671-5679 | JJ | denotes | specific |
T3028 | 5680-5687 | JJ | denotes | genetic |
T3029 | 5702-5707 | VBN | denotes | found |
T3030 | 5708-5710 | IN | denotes | in |
T3031 | 5711-5717 | NN | denotes | animal |
T3032 | 5718-5724 | NNS | denotes | models |
T3033 | 5725-5728 | MD | denotes | can |
T3034 | 5729-5733 | RB | denotes | then |
T3035 | 5734-5736 | VB | denotes | be |
T3036 | 5750-5752 | IN | denotes | in |
T3037 | 5753-5758 | JJ | denotes | human |
T3038 | 5759-5770 | NNS | denotes | populations |
T3039 | 5770-5771 | . | denotes | . |
T3040 | 5771-5930 | sentence | denotes | We screened mice treated with the chemical mutagen N-ethyl-N-nitrosourea (ENU) for lines with developmental defects that present in the perinatal period [14]. |
T3041 | 5772-5774 | PRP | denotes | We |
T3042 | 5775-5783 | VBD | denotes | screened |
T3043 | 5784-5788 | NNS | denotes | mice |
T3044 | 5789-5796 | VBN | denotes | treated |
T3045 | 5797-5801 | IN | denotes | with |
T3046 | 5802-5805 | DT | denotes | the |
T3047 | 5815-5822 | NN | denotes | mutagen |
T3048 | 5806-5814 | JJ | denotes | chemical |
T3049 | 5823-5824 | NN | denotes | N |
T3050 | 5825-5830 | NN | denotes | ethyl |
T3051 | 5824-5825 | HYPH | denotes | - |
T3052 | 5830-5831 | HYPH | denotes | - |
T3053 | 5831-5832 | NN | denotes | N |
T3054 | 5833-5844 | NN | denotes | nitrosourea |
T3055 | 5832-5833 | HYPH | denotes | - |
T3056 | 5845-5846 | -LRB- | denotes | ( |
T3057 | 5846-5849 | NN | denotes | ENU |
T3058 | 5849-5850 | -RRB- | denotes | ) |
T3059 | 5851-5854 | IN | denotes | for |
T3060 | 5855-5860 | NNS | denotes | lines |
T3061 | 5861-5865 | IN | denotes | with |
T3062 | 5866-5879 | JJ | denotes | developmental |
T3063 | 5880-5887 | NNS | denotes | defects |
T3064 | 5888-5892 | WDT | denotes | that |
T3065 | 5893-5900 | VBP | denotes | present |
T3066 | 5901-5903 | IN | denotes | in |
T3067 | 5904-5907 | DT | denotes | the |
T3068 | 5918-5924 | NN | denotes | period |
T3069 | 5908-5917 | JJ | denotes | perinatal |
T3070 | 5925-5926 | -LRB- | denotes | [ |
T3071 | 5926-5928 | CD | denotes | 14 |
T3072 | 5928-5929 | -RRB- | denotes | ] |
T3073 | 5929-5930 | . | denotes | . |
T3074 | 5930-6104 | sentence | denotes | From this screen, we identified a line of mice carrying a recessive mutation that results in primary pulmonary hypoplasia and abnormal diaphragmatic and cardiac development. |
T3075 | 5931-5935 | IN | denotes | From |
T3076 | 5952-5962 | VBD | denotes | identified |
T3077 | 5936-5940 | DT | denotes | this |
T3078 | 5941-5947 | NN | denotes | screen |
T3079 | 5947-5949 | , | denotes | , |
T3080 | 5949-5951 | PRP | denotes | we |
T3081 | 5963-5964 | DT | denotes | a |
T3082 | 5965-5969 | NN | denotes | line |
T3083 | 5970-5972 | IN | denotes | of |
T3084 | 5973-5977 | NNS | denotes | mice |
T3085 | 5978-5986 | VBG | denotes | carrying |
T3086 | 5987-5988 | DT | denotes | a |
T3087 | 5999-6007 | NN | denotes | mutation |
T3088 | 5989-5998 | JJ | denotes | recessive |
T3089 | 6008-6012 | WDT | denotes | that |
T3090 | 6013-6020 | VBZ | denotes | results |
T3091 | 6021-6023 | IN | denotes | in |
T3092 | 6024-6031 | JJ | denotes | primary |
T3093 | 6042-6052 | NN | denotes | hypoplasia |
T3094 | 6032-6041 | JJ | denotes | pulmonary |
T3095 | 6053-6056 | CC | denotes | and |
T3096 | 6057-6065 | JJ | denotes | abnormal |
T3097 | 6092-6103 | NN | denotes | development |
T3098 | 6066-6079 | JJ | denotes | diaphragmatic |
T3099 | 6080-6083 | CC | denotes | and |
T3100 | 6084-6091 | JJ | denotes | cardiac |
T3101 | 6103-6104 | . | denotes | . |
T3102 | 6104-6309 | sentence | denotes | Positional cloning analysis identified Fog2 (Zfpm2) as a likely candidate, and DNA sequencing revealed a mutation in a splice donor site that generates an abnormal transcript encoding a truncated protein. |
T3103 | 6105-6115 | JJ | denotes | Positional |
T3104 | 6124-6132 | NN | denotes | analysis |
T3105 | 6116-6123 | NN | denotes | cloning |
T3106 | 6133-6143 | VBD | denotes | identified |
T3107 | 6144-6148 | NN | denotes | Fog2 |
T3108 | 6149-6150 | -LRB- | denotes | ( |
T3109 | 6150-6155 | NN | denotes | Zfpm2 |
T3110 | 6155-6156 | -RRB- | denotes | ) |
T3111 | 6157-6159 | IN | denotes | as |
T3112 | 6160-6161 | DT | denotes | a |
T3113 | 6169-6178 | NN | denotes | candidate |
T3114 | 6162-6168 | JJ | denotes | likely |
T3115 | 6178-6180 | , | denotes | , |
T3116 | 6180-6183 | CC | denotes | and |
T3117 | 6184-6187 | NN | denotes | DNA |
T3118 | 6188-6198 | NN | denotes | sequencing |
T3119 | 6199-6207 | VBD | denotes | revealed |
T3120 | 6208-6209 | DT | denotes | a |
T3121 | 6210-6218 | NN | denotes | mutation |
T3122 | 6219-6221 | IN | denotes | in |
T3123 | 6222-6223 | DT | denotes | a |
T3124 | 6237-6241 | NN | denotes | site |
T3125 | 6224-6230 | NN | denotes | splice |
T3126 | 6231-6236 | NN | denotes | donor |
T3127 | 6242-6246 | WDT | denotes | that |
T3128 | 6247-6256 | VBZ | denotes | generates |
T3129 | 6257-6259 | DT | denotes | an |
T3130 | 6269-6279 | NN | denotes | transcript |
T3131 | 6260-6268 | JJ | denotes | abnormal |
T3132 | 6280-6288 | VBG | denotes | encoding |
T3133 | 6289-6290 | DT | denotes | a |
T3134 | 6301-6308 | NN | denotes | protein |
T3135 | 6291-6300 | VBN | denotes | truncated |
T3136 | 6308-6309 | . | denotes | . |
T3137 | 6309-6571 | sentence | denotes | This result suggested that we examine the orthologous gene in humans with similar developmental defects, and we report the finding of a de novo nonsense mutation in FOG2 in a patient who died at birth with a diaphragmatic defect and severe pulmonary hypoplasia. |
T3138 | 6310-6314 | DT | denotes | This |
T3139 | 6315-6321 | NN | denotes | result |
T3140 | 6322-6331 | VBD | denotes | suggested |
T3141 | 6332-6336 | IN | denotes | that |
T3142 | 6340-6347 | VBP | denotes | examine |
T3143 | 6337-6339 | PRP | denotes | we |
T3144 | 6348-6351 | DT | denotes | the |
T3145 | 6364-6368 | NN | denotes | gene |
T3146 | 6352-6363 | JJ | denotes | orthologous |
T3147 | 6369-6371 | IN | denotes | in |
T3148 | 6372-6378 | NNS | denotes | humans |
T3149 | 6379-6383 | IN | denotes | with |
T3150 | 6384-6391 | JJ | denotes | similar |
T3151 | 6406-6413 | NNS | denotes | defects |
T3152 | 6392-6405 | JJ | denotes | developmental |
T3153 | 6413-6415 | , | denotes | , |
T3154 | 6415-6418 | CC | denotes | and |
T3155 | 6419-6421 | PRP | denotes | we |
T3156 | 6422-6428 | VBP | denotes | report |
T3157 | 6429-6432 | DT | denotes | the |
T3158 | 6433-6440 | NN | denotes | finding |
T3159 | 6441-6443 | IN | denotes | of |
T3160 | 6444-6445 | DT | denotes | a |
T3161 | 6463-6471 | NN | denotes | mutation |
T3162 | 6446-6448 | FW | denotes | de |
T3163 | 6449-6453 | FW | denotes | novo |
T3164 | 6454-6462 | NN | denotes | nonsense |
T3165 | 6472-6474 | IN | denotes | in |
T3166 | 6475-6479 | NN | denotes | FOG2 |
T3167 | 6480-6482 | IN | denotes | in |
T3168 | 6483-6484 | DT | denotes | a |
T3169 | 6485-6492 | NN | denotes | patient |
T3170 | 6493-6496 | WP | denotes | who |
T3171 | 6497-6501 | VBD | denotes | died |
T3172 | 6502-6504 | IN | denotes | at |
T3173 | 6505-6510 | NN | denotes | birth |
T3174 | 6511-6515 | IN | denotes | with |
T3175 | 6516-6517 | DT | denotes | a |
T3176 | 6532-6538 | NN | denotes | defect |
T3177 | 6518-6531 | JJ | denotes | diaphragmatic |
T3178 | 6539-6542 | CC | denotes | and |
T3179 | 6543-6549 | JJ | denotes | severe |
T3180 | 6560-6570 | NN | denotes | hypoplasia |
T3181 | 6550-6559 | JJ | denotes | pulmonary |
T3182 | 6570-6571 | . | denotes | . |
T3183 | 6571-6655 | sentence | denotes | This is the first reported mutation associated with these abnormalities in a human. |
T3184 | 6572-6576 | DT | denotes | This |
T3185 | 6577-6579 | VBZ | denotes | is |
T3186 | 6580-6583 | DT | denotes | the |
T3187 | 6599-6607 | NN | denotes | mutation |
T3188 | 6584-6589 | JJ | denotes | first |
T3189 | 6590-6598 | VBN | denotes | reported |
T3190 | 6608-6618 | JJ | denotes | associated |
T3191 | 6619-6623 | IN | denotes | with |
T3192 | 6624-6629 | DT | denotes | these |
T3193 | 6630-6643 | NNS | denotes | abnormalities |
T3194 | 6644-6646 | IN | denotes | in |
T3195 | 6647-6648 | DT | denotes | a |
T3196 | 6649-6654 | NN | denotes | human |
T3197 | 6654-6655 | . | denotes | . |
T3198 | 6655-6795 | sentence | denotes | We present additional data that provide direct evidence that pulmonary hypoplasia may be a primary component of this spectrum of disorders. |
T3199 | 6656-6658 | PRP | denotes | We |
T3200 | 6659-6666 | VBP | denotes | present |
T3201 | 6667-6677 | JJ | denotes | additional |
T3202 | 6678-6682 | NNS | denotes | data |
T3203 | 6683-6687 | WDT | denotes | that |
T3204 | 6688-6695 | VBP | denotes | provide |
T3205 | 6696-6702 | JJ | denotes | direct |
T3206 | 6703-6711 | NN | denotes | evidence |
T3207 | 6712-6716 | IN | denotes | that |
T3208 | 6742-6744 | VB | denotes | be |
T3209 | 6717-6726 | JJ | denotes | pulmonary |
T3210 | 6727-6737 | NN | denotes | hypoplasia |
T3211 | 6738-6741 | MD | denotes | may |
T3212 | 6745-6746 | DT | denotes | a |
T3213 | 6755-6764 | NN | denotes | component |
T3214 | 6747-6754 | JJ | denotes | primary |
T3215 | 6765-6767 | IN | denotes | of |
T3216 | 6768-6772 | DT | denotes | this |
T3217 | 6773-6781 | NN | denotes | spectrum |
T3218 | 6782-6784 | IN | denotes | of |
T3219 | 6785-6794 | NNS | denotes | disorders |
T3220 | 6794-6795 | . | denotes | . |
T5356 | 6806-6820 | NN | denotes | Identification |
T5357 | 6821-6823 | IN | denotes | of |
T5358 | 6824-6827 | DT | denotes | the |
T5359 | 6840-6848 | NN | denotes | Mutation |
T5360 | 6828-6834 | JJ | denotes | little |
T5361 | 6835-6839 | NN | denotes | lung |
T5362 | 6849-6851 | IN | denotes | in |
T5363 | 6852-6856 | NN | denotes | Fog2 |
T5364 | 6856-6991 | sentence | denotes | We screened third-generation progeny of ENU-mutagenized mice at embryonic day 18.5 (E18.5) for abnormal developmental phenotypes [14]. |
T5365 | 6857-6859 | PRP | denotes | We |
T5366 | 6860-6868 | VBD | denotes | screened |
T5367 | 6869-6874 | JJ | denotes | third |
T5368 | 6875-6885 | NN | denotes | generation |
T5369 | 6874-6875 | HYPH | denotes | - |
T5370 | 6886-6893 | NN | denotes | progeny |
T5371 | 6894-6896 | IN | denotes | of |
T5372 | 6897-6900 | NN | denotes | ENU |
T5373 | 6901-6912 | VBN | denotes | mutagenized |
T5374 | 6900-6901 | HYPH | denotes | - |
T5375 | 6913-6917 | NNS | denotes | mice |
T5376 | 6918-6920 | IN | denotes | at |
T5377 | 6921-6930 | JJ | denotes | embryonic |
T5378 | 6931-6934 | NN | denotes | day |
T5379 | 6935-6939 | CD | denotes | 18.5 |
T5380 | 6940-6941 | -LRB- | denotes | ( |
T5381 | 6941-6946 | NN | denotes | E18.5 |
T5382 | 6946-6947 | -RRB- | denotes | ) |
T5383 | 6948-6951 | IN | denotes | for |
T5384 | 6952-6960 | JJ | denotes | abnormal |
T5385 | 6975-6985 | NNS | denotes | phenotypes |
T5386 | 6961-6974 | JJ | denotes | developmental |
T5387 | 6986-6987 | -LRB- | denotes | [ |
T5388 | 6987-6989 | CD | denotes | 14 |
T5389 | 6989-6990 | -RRB- | denotes | ] |
T5390 | 6990-6991 | . | denotes | . |
T5391 | 6991-7124 | sentence | denotes | One line of mice was found to have multiple embryos in independent litters that displayed pulmonary hypoplasia and a thin diaphragm. |
T5392 | 6992-6995 | CD | denotes | One |
T5393 | 6996-7000 | NN | denotes | line |
T5394 | 7013-7018 | VBN | denotes | found |
T5395 | 7001-7003 | IN | denotes | of |
T5396 | 7004-7008 | NNS | denotes | mice |
T5397 | 7009-7012 | VBD | denotes | was |
T5398 | 7019-7021 | TO | denotes | to |
T5399 | 7022-7026 | VB | denotes | have |
T5400 | 7027-7035 | JJ | denotes | multiple |
T5401 | 7036-7043 | NNS | denotes | embryos |
T5402 | 7044-7046 | IN | denotes | in |
T5403 | 7047-7058 | JJ | denotes | independent |
T5404 | 7059-7066 | NNS | denotes | litters |
T5405 | 7067-7071 | WDT | denotes | that |
T5406 | 7072-7081 | VBD | denotes | displayed |
T5407 | 7082-7091 | JJ | denotes | pulmonary |
T5408 | 7092-7102 | NN | denotes | hypoplasia |
T5409 | 7103-7106 | CC | denotes | and |
T5410 | 7107-7108 | DT | denotes | a |
T5411 | 7114-7123 | NN | denotes | diaphragm |
T5412 | 7109-7113 | JJ | denotes | thin |
T5413 | 7123-7124 | . | denotes | . |
T5414 | 7124-7279 | sentence | denotes | The mutation, which we called little lung (lil), was mapped to Chromosome 15 by utilizing a strategy of interval haplotype analysis (data not shown) [15]. |
T5415 | 7125-7128 | DT | denotes | The |
T5416 | 7129-7137 | NN | denotes | mutation |
T5417 | 7178-7184 | VBN | denotes | mapped |
T5418 | 7137-7139 | , | denotes | , |
T5419 | 7139-7144 | WDT | denotes | which |
T5420 | 7148-7154 | VBD | denotes | called |
T5421 | 7145-7147 | PRP | denotes | we |
T5422 | 7155-7161 | JJ | denotes | little |
T5423 | 7162-7166 | NN | denotes | lung |
T5424 | 7167-7168 | -LRB- | denotes | ( |
T5425 | 7168-7171 | NN | denotes | lil |
T5426 | 7171-7172 | -RRB- | denotes | ) |
T5427 | 7172-7174 | , | denotes | , |
T5428 | 7174-7177 | VBD | denotes | was |
T5429 | 7185-7187 | IN | denotes | to |
T5430 | 7188-7198 | NN | denotes | Chromosome |
T5431 | 7199-7201 | CD | denotes | 15 |
T5432 | 7202-7204 | IN | denotes | by |
T5433 | 7205-7214 | VBG | denotes | utilizing |
T5434 | 7215-7216 | DT | denotes | a |
T5435 | 7217-7225 | NN | denotes | strategy |
T5436 | 7226-7228 | IN | denotes | of |
T5437 | 7229-7237 | JJ | denotes | interval |
T5438 | 7248-7256 | NN | denotes | analysis |
T5439 | 7238-7247 | NN | denotes | haplotype |
T5440 | 7257-7258 | -LRB- | denotes | ( |
T5441 | 7267-7272 | VBN | denotes | shown |
T5442 | 7258-7262 | NNS | denotes | data |
T5443 | 7263-7266 | RB | denotes | not |
T5444 | 7272-7273 | -RRB- | denotes | ) |
T5445 | 7274-7275 | -LRB- | denotes | [ |
T5446 | 7275-7277 | CD | denotes | 15 |
T5447 | 7277-7278 | -RRB- | denotes | ] |
T5448 | 7278-7279 | . | denotes | . |
T5449 | 7279-7351 | sentence | denotes | For high-resolution mapping, F2 progeny from two crosses were analyzed. |
T5450 | 7280-7283 | IN | denotes | For |
T5451 | 7342-7350 | VBN | denotes | analyzed |
T5452 | 7284-7288 | JJ | denotes | high |
T5453 | 7289-7299 | NN | denotes | resolution |
T5454 | 7288-7289 | HYPH | denotes | - |
T5455 | 7300-7307 | NN | denotes | mapping |
T5456 | 7307-7309 | , | denotes | , |
T5457 | 7309-7311 | NN | denotes | F2 |
T5458 | 7312-7319 | NN | denotes | progeny |
T5459 | 7320-7324 | IN | denotes | from |
T5460 | 7325-7328 | CD | denotes | two |
T5461 | 7329-7336 | NNS | denotes | crosses |
T5462 | 7337-7341 | VBD | denotes | were |
T5463 | 7350-7351 | . | denotes | . |
T5464 | 7351-7516 | sentence | denotes | In 450 progeny of an intercross of F1 (A/J × FVB/N) lil/+ mice, the interval containing the mutation was defined by 19 recombinants between D15Mit220 and D15Mit154. |
T5465 | 7352-7354 | IN | denotes | In |
T5466 | 7457-7464 | VBN | denotes | defined |
T5467 | 7355-7358 | CD | denotes | 450 |
T5468 | 7359-7366 | NN | denotes | progeny |
T5469 | 7367-7369 | IN | denotes | of |
T5470 | 7370-7372 | DT | denotes | an |
T5471 | 7373-7383 | NN | denotes | intercross |
T5472 | 7384-7386 | IN | denotes | of |
T5473 | 7387-7389 | NN | denotes | F1 |
T5474 | 7410-7414 | NNS | denotes | mice |
T5475 | 7390-7391 | -LRB- | denotes | ( |
T5476 | 7393-7394 | NN | denotes | J |
T5477 | 7391-7392 | NN | denotes | A |
T5478 | 7392-7393 | SYM | denotes | / |
T5479 | 7395-7396 | SYM | denotes | × |
T5480 | 7397-7400 | NN | denotes | FVB |
T5481 | 7401-7402 | NN | denotes | N |
T5482 | 7400-7401 | HYPH | denotes | / |
T5483 | 7402-7403 | -RRB- | denotes | ) |
T5484 | 7404-7407 | NN | denotes | lil |
T5485 | 7407-7408 | HYPH | denotes | / |
T5486 | 7408-7409 | SYM | denotes | + |
T5487 | 7414-7416 | , | denotes | , |
T5488 | 7416-7419 | DT | denotes | the |
T5489 | 7420-7428 | NN | denotes | interval |
T5490 | 7429-7439 | VBG | denotes | containing |
T5491 | 7440-7443 | DT | denotes | the |
T5492 | 7444-7452 | NN | denotes | mutation |
T5493 | 7453-7456 | VBD | denotes | was |
T5494 | 7465-7467 | IN | denotes | by |
T5495 | 7468-7470 | CD | denotes | 19 |
T5496 | 7471-7483 | NNS | denotes | recombinants |
T5497 | 7484-7491 | IN | denotes | between |
T5498 | 7492-7501 | NN | denotes | D15Mit220 |
T5499 | 7502-7505 | CC | denotes | and |
T5500 | 7506-7515 | NN | denotes | D15Mit154 |
T5501 | 7515-7516 | . | denotes | . |
T5502 | 7516-7651 | sentence | denotes | Because of the lack of informative markers within this interval, an additional 39 F2 progeny from an A/J × C57BL/6J cross were tested. |
T5503 | 7517-7524 | IN | denotes | Because |
T5504 | 7644-7650 | VBN | denotes | tested |
T5505 | 7525-7527 | IN | denotes | of |
T5506 | 7528-7531 | DT | denotes | the |
T5507 | 7532-7536 | NN | denotes | lack |
T5508 | 7537-7539 | IN | denotes | of |
T5509 | 7540-7551 | JJ | denotes | informative |
T5510 | 7552-7559 | NNS | denotes | markers |
T5511 | 7560-7566 | IN | denotes | within |
T5512 | 7567-7571 | DT | denotes | this |
T5513 | 7572-7580 | NN | denotes | interval |
T5514 | 7580-7582 | , | denotes | , |
T5515 | 7582-7584 | DT | denotes | an |
T5516 | 7596-7598 | CD | denotes | 39 |
T5517 | 7585-7595 | JJ | denotes | additional |
T5518 | 7602-7609 | NN | denotes | progeny |
T5519 | 7599-7601 | NN | denotes | F2 |
T5520 | 7610-7614 | IN | denotes | from |
T5521 | 7615-7617 | DT | denotes | an |
T5522 | 7633-7638 | NN | denotes | cross |
T5523 | 7618-7619 | NN | denotes | A |
T5524 | 7620-7621 | NN | denotes | J |
T5525 | 7619-7620 | HYPH | denotes | / |
T5526 | 7622-7623 | SYM | denotes | × |
T5527 | 7624-7629 | NN | denotes | C57BL |
T5528 | 7630-7632 | NN | denotes | 6J |
T5529 | 7629-7630 | HYPH | denotes | / |
T5530 | 7639-7643 | VBD | denotes | were |
T5531 | 7650-7651 | . | denotes | . |
T5532 | 7651-7771 | sentence | denotes | The identification of two recombinants established D15Mit85 as the proximal and D15Mit5 as the distal flanking markers. |
T5533 | 7652-7655 | DT | denotes | The |
T5534 | 7656-7670 | NN | denotes | identification |
T5535 | 7691-7702 | VBD | denotes | established |
T5536 | 7671-7673 | IN | denotes | of |
T5537 | 7674-7677 | CD | denotes | two |
T5538 | 7678-7690 | NNS | denotes | recombinants |
T5539 | 7703-7711 | NN | denotes | D15Mit85 |
T5540 | 7712-7714 | IN | denotes | as |
T5541 | 7715-7718 | DT | denotes | the |
T5542 | 7719-7727 | JJ | denotes | proximal |
T5543 | 7728-7731 | CC | denotes | and |
T5544 | 7732-7739 | NN | denotes | D15Mit5 |
T5545 | 7740-7742 | IN | denotes | as |
T5546 | 7743-7746 | DT | denotes | the |
T5547 | 7747-7753 | JJ | denotes | distal |
T5548 | 7754-7762 | NN | denotes | flanking |
T5549 | 7763-7770 | NNS | denotes | markers |
T5550 | 7770-7771 | . | denotes | . |
T5551 | 7771-7879 | sentence | denotes | The lil phenotype was identified at E18.5 to have bilateral pulmonary hypoplasia and an abnormal diaphragm. |
T5552 | 7772-7775 | DT | denotes | The |
T5553 | 7780-7789 | NN | denotes | phenotype |
T5554 | 7776-7779 | NN | denotes | lil |
T5555 | 7794-7804 | VBN | denotes | identified |
T5556 | 7790-7793 | VBD | denotes | was |
T5557 | 7805-7807 | IN | denotes | at |
T5558 | 7808-7813 | NN | denotes | E18.5 |
T5559 | 7814-7816 | TO | denotes | to |
T5560 | 7817-7821 | VB | denotes | have |
T5561 | 7822-7831 | JJ | denotes | bilateral |
T5562 | 7842-7852 | NN | denotes | hypoplasia |
T5563 | 7832-7841 | JJ | denotes | pulmonary |
T5564 | 7853-7856 | CC | denotes | and |
T5565 | 7857-7859 | DT | denotes | an |
T5566 | 7869-7878 | NN | denotes | diaphragm |
T5567 | 7860-7868 | JJ | denotes | abnormal |
T5568 | 7878-7879 | . | denotes | . |
T5569 | 7879-7956 | sentence | denotes | Pulmonary hypoplasia was apparent in all mutant mice that survived to birth. |
T5570 | 7880-7889 | JJ | denotes | Pulmonary |
T5571 | 7890-7900 | NN | denotes | hypoplasia |
T5572 | 7901-7904 | VBD | denotes | was |
T5573 | 7905-7913 | JJ | denotes | apparent |
T5574 | 7914-7916 | IN | denotes | in |
T5575 | 7917-7920 | DT | denotes | all |
T5576 | 7928-7932 | NNS | denotes | mice |
T5577 | 7921-7927 | NN | denotes | mutant |
T5578 | 7933-7937 | WDT | denotes | that |
T5579 | 7938-7946 | VBD | denotes | survived |
T5580 | 7947-7949 | IN | denotes | to |
T5581 | 7950-7955 | NN | denotes | birth |
T5582 | 7955-7956 | . | denotes | . |
T5583 | 7956-8141 | sentence | denotes | In a comparison between wild-type and mutant mice found dead on day one of life, body weights were not different; however, the lung weights were significantly lower in the mutant mice. |
T5584 | 7957-7959 | IN | denotes | In |
T5585 | 8097-8101 | VBD | denotes | were |
T5586 | 7960-7961 | DT | denotes | a |
T5587 | 7962-7972 | NN | denotes | comparison |
T5588 | 7973-7980 | IN | denotes | between |
T5589 | 7981-7985 | JJ | denotes | wild |
T5590 | 7986-7990 | NN | denotes | type |
T5591 | 7985-7986 | HYPH | denotes | - |
T5592 | 8002-8006 | NNS | denotes | mice |
T5593 | 7991-7994 | CC | denotes | and |
T5594 | 7995-8001 | NN | denotes | mutant |
T5595 | 8007-8012 | VBN | denotes | found |
T5596 | 8013-8017 | JJ | denotes | dead |
T5597 | 8018-8020 | IN | denotes | on |
T5598 | 8021-8024 | NN | denotes | day |
T5599 | 8025-8028 | CD | denotes | one |
T5600 | 8029-8031 | IN | denotes | of |
T5601 | 8032-8036 | NN | denotes | life |
T5602 | 8036-8038 | , | denotes | , |
T5603 | 8038-8042 | NN | denotes | body |
T5604 | 8043-8050 | NNS | denotes | weights |
T5605 | 8051-8055 | VBD | denotes | were |
T5606 | 8056-8059 | RB | denotes | not |
T5607 | 8060-8069 | JJ | denotes | different |
T5608 | 8069-8070 | : | denotes | ; |
T5609 | 8071-8078 | RB | denotes | however |
T5610 | 8078-8080 | , | denotes | , |
T5611 | 8080-8083 | DT | denotes | the |
T5612 | 8089-8096 | NNS | denotes | weights |
T5613 | 8084-8088 | NN | denotes | lung |
T5614 | 8102-8115 | RB | denotes | significantly |
T5615 | 8116-8121 | JJR | denotes | lower |
T5616 | 8122-8124 | IN | denotes | in |
T5617 | 8125-8128 | DT | denotes | the |
T5618 | 8136-8140 | NNS | denotes | mice |
T5619 | 8129-8135 | NN | denotes | mutant |
T5620 | 8140-8141 | . | denotes | . |
T5621 | 8141-8260 | sentence | denotes | The average mutant lung weight was 9.6 ± 2.5 mg while the average wild-type lung weight was 26.4 ± 4.6 mg (p < 0.001). |
T5622 | 8142-8145 | DT | denotes | The |
T5623 | 8166-8172 | NN | denotes | weight |
T5624 | 8146-8153 | JJ | denotes | average |
T5625 | 8154-8160 | NN | denotes | mutant |
T5626 | 8161-8165 | NN | denotes | lung |
T5627 | 8173-8176 | VBD | denotes | was |
T5628 | 8177-8180 | CD | denotes | 9.6 |
T5629 | 8183-8186 | CD | denotes | 2.5 |
T5630 | 8181-8182 | SYM | denotes | ± |
T5631 | 8187-8189 | NN | denotes | mg |
T5632 | 8190-8195 | IN | denotes | while |
T5633 | 8230-8233 | VBD | denotes | was |
T5634 | 8196-8199 | DT | denotes | the |
T5635 | 8223-8229 | NN | denotes | weight |
T5636 | 8200-8207 | JJ | denotes | average |
T5637 | 8208-8212 | JJ | denotes | wild |
T5638 | 8213-8217 | NN | denotes | type |
T5639 | 8212-8213 | HYPH | denotes | - |
T5640 | 8218-8222 | NN | denotes | lung |
T5641 | 8234-8238 | CD | denotes | 26.4 |
T5642 | 8241-8244 | CD | denotes | 4.6 |
T5643 | 8239-8240 | SYM | denotes | ± |
T5644 | 8245-8247 | NN | denotes | mg |
T5645 | 8248-8249 | -LRB- | denotes | ( |
T5646 | 8253-8258 | CD | denotes | 0.001 |
T5647 | 8249-8250 | NN | denotes | p |
T5648 | 8251-8252 | SYM | denotes | < |
T5649 | 8258-8259 | -RRB- | denotes | ) |
T5650 | 8259-8260 | . | denotes | . |
T5651 | 8260-8408 | sentence | denotes | All lungs from mutant mice were lacking an accessory lobe on the right side and had underdevelopment of the anterior right middle lobe (Figure 1A). |
T5652 | 8261-8264 | DT | denotes | All |
T5653 | 8265-8270 | NNS | denotes | lungs |
T5654 | 8293-8300 | VBG | denotes | lacking |
T5655 | 8271-8275 | IN | denotes | from |
T5656 | 8276-8282 | NN | denotes | mutant |
T5657 | 8283-8287 | NNS | denotes | mice |
T5658 | 8288-8292 | VBD | denotes | were |
T5659 | 8301-8303 | DT | denotes | an |
T5660 | 8314-8318 | NN | denotes | lobe |
T5661 | 8304-8313 | JJ | denotes | accessory |
T5662 | 8319-8321 | IN | denotes | on |
T5663 | 8322-8325 | DT | denotes | the |
T5664 | 8332-8336 | NN | denotes | side |
T5665 | 8326-8331 | JJ | denotes | right |
T5666 | 8337-8340 | CC | denotes | and |
T5667 | 8341-8344 | VBD | denotes | had |
T5668 | 8345-8361 | NN | denotes | underdevelopment |
T5669 | 8362-8364 | IN | denotes | of |
T5670 | 8365-8368 | DT | denotes | the |
T5671 | 8391-8395 | NN | denotes | lobe |
T5672 | 8369-8377 | JJ | denotes | anterior |
T5673 | 8378-8383 | JJ | denotes | right |
T5674 | 8384-8390 | JJ | denotes | middle |
T5675 | 8396-8397 | -LRB- | denotes | ( |
T5676 | 8397-8403 | NN | denotes | Figure |
T5677 | 8404-8406 | CD | denotes | 1A |
T5678 | 8406-8407 | -RRB- | denotes | ) |
T5679 | 8407-8408 | . | denotes | . |
T5680 | 8408-8507 | sentence | denotes | Diaphragms from mutant lil mice were intact, but muscularization was absent in the dorsal regions. |
T5681 | 8409-8419 | NNS | denotes | Diaphragms |
T5682 | 8441-8445 | VBD | denotes | were |
T5683 | 8420-8424 | IN | denotes | from |
T5684 | 8425-8431 | NN | denotes | mutant |
T5685 | 8436-8440 | NNS | denotes | mice |
T5686 | 8432-8435 | NN | denotes | lil |
T5687 | 8446-8452 | JJ | denotes | intact |
T5688 | 8452-8454 | , | denotes | , |
T5689 | 8454-8457 | CC | denotes | but |
T5690 | 8458-8473 | NN | denotes | muscularization |
T5691 | 8474-8477 | VBD | denotes | was |
T5692 | 8478-8484 | JJ | denotes | absent |
T5693 | 8485-8487 | IN | denotes | in |
T5694 | 8488-8491 | DT | denotes | the |
T5695 | 8499-8506 | NNS | denotes | regions |
T5696 | 8492-8498 | JJ | denotes | dorsal |
T5697 | 8506-8507 | . | denotes | . |
T5698 | 8507-8571 | sentence | denotes | Myotubules were present in a limited and abnormal distribution. |
T5699 | 8508-8518 | NNS | denotes | Myotubules |
T5700 | 8519-8523 | VBD | denotes | were |
T5701 | 8524-8531 | JJ | denotes | present |
T5702 | 8532-8534 | IN | denotes | in |
T5703 | 8535-8536 | DT | denotes | a |
T5704 | 8558-8570 | NN | denotes | distribution |
T5705 | 8537-8544 | JJ | denotes | limited |
T5706 | 8545-8548 | CC | denotes | and |
T5707 | 8549-8557 | JJ | denotes | abnormal |
T5708 | 8570-8571 | . | denotes | . |
T5709 | 8571-8748 | sentence | denotes | More specifically, myotubules normally radiate in a mediolateral fashion to meet the lateral body walls, with a normal paucity of muscle fibers in the central tendonous region. |
T5710 | 8572-8576 | RBR | denotes | More |
T5711 | 8577-8589 | RB | denotes | specifically |
T5712 | 8611-8618 | VBP | denotes | radiate |
T5713 | 8589-8591 | , | denotes | , |
T5714 | 8591-8601 | NNS | denotes | myotubules |
T5715 | 8602-8610 | RB | denotes | normally |
T5716 | 8619-8621 | IN | denotes | in |
T5717 | 8622-8623 | DT | denotes | a |
T5718 | 8637-8644 | NN | denotes | fashion |
T5719 | 8624-8636 | JJ | denotes | mediolateral |
T5720 | 8645-8647 | TO | denotes | to |
T5721 | 8648-8652 | VB | denotes | meet |
T5722 | 8653-8656 | DT | denotes | the |
T5723 | 8670-8675 | NNS | denotes | walls |
T5724 | 8657-8664 | JJ | denotes | lateral |
T5725 | 8665-8669 | NN | denotes | body |
T5726 | 8675-8677 | , | denotes | , |
T5727 | 8677-8681 | IN | denotes | with |
T5728 | 8682-8683 | DT | denotes | a |
T5729 | 8691-8698 | NN | denotes | paucity |
T5730 | 8684-8690 | JJ | denotes | normal |
T5731 | 8699-8701 | IN | denotes | of |
T5732 | 8702-8708 | NN | denotes | muscle |
T5733 | 8709-8715 | NNS | denotes | fibers |
T5734 | 8716-8718 | IN | denotes | in |
T5735 | 8719-8722 | DT | denotes | the |
T5736 | 8741-8747 | NN | denotes | region |
T5737 | 8723-8730 | JJ | denotes | central |
T5738 | 8731-8740 | JJ | denotes | tendonous |
T5739 | 8747-8748 | . | denotes | . |
T5740 | 8748-8907 | sentence | denotes | In the mutant diaphragm, myotubules radiated in a dorsal–ventral orientation, and muscle tissue did not meet the entire surface of the body walls (Figure 1B). |
T5741 | 8749-8751 | IN | denotes | In |
T5742 | 8785-8793 | VBN | denotes | radiated |
T5743 | 8752-8755 | DT | denotes | the |
T5744 | 8763-8772 | NN | denotes | diaphragm |
T5745 | 8756-8762 | NN | denotes | mutant |
T5746 | 8772-8774 | , | denotes | , |
T5747 | 8774-8784 | NNS | denotes | myotubules |
T5748 | 8794-8796 | IN | denotes | in |
T5749 | 8797-8798 | DT | denotes | a |
T5750 | 8814-8825 | NN | denotes | orientation |
T5751 | 8799-8805 | JJ | denotes | dorsal |
T5752 | 8806-8813 | JJ | denotes | ventral |
T5753 | 8805-8806 | HYPH | denotes | – |
T5754 | 8825-8827 | , | denotes | , |
T5755 | 8827-8830 | CC | denotes | and |
T5756 | 8831-8837 | NN | denotes | muscle |
T5757 | 8838-8844 | NN | denotes | tissue |
T5758 | 8853-8857 | VB | denotes | meet |
T5759 | 8845-8848 | VBD | denotes | did |
T5760 | 8849-8852 | RB | denotes | not |
T5869 | 9855-9868 | RB | denotes | progressively |
T5870 | 9869-9875 | JJR | denotes | higher |
T5871 | 9881-9883 | IN | denotes | of |
T5872 | 9884-9890 | NN | denotes | demise |
T5873 | 9891-9898 | IN | denotes | between |
T5874 | 9899-9904 | NN | denotes | E13.5 |
T5875 | 9905-9908 | CC | denotes | and |
T5876 | 9909-9914 | NN | denotes | E15.5 |
T5877 | 9914-9915 | . | denotes | . |
T5878 | 9915-10012 | sentence | denotes | At E12.5, 20 out of 87 (23%) were homozygous for the mutation, and all of these appeared viable. |
T5879 | 9916-9918 | IN | denotes | At |
T5880 | 9945-9949 | VBD | denotes | were |
T5881 | 9919-9924 | NN | denotes | E12.5 |
T5882 | 9924-9926 | , | denotes | , |
T5883 | 9926-9928 | CD | denotes | 20 |
T5884 | 9936-9938 | CD | denotes | 87 |
T5885 | 9929-9932 | IN | denotes | out |
T5886 | 9933-9935 | IN | denotes | of |
T5887 | 9939-9940 | -LRB- | denotes | ( |
T5888 | 9942-9943 | NN | denotes | % |
T5889 | 9940-9942 | CD | denotes | 23 |
T5890 | 9943-9944 | -RRB- | denotes | ) |
T5891 | 9950-9960 | JJ | denotes | homozygous |
T5892 | 9961-9964 | IN | denotes | for |
T5893 | 9965-9968 | DT | denotes | the |
T5894 | 9969-9977 | NN | denotes | mutation |
T5895 | 9977-9979 | , | denotes | , |
T5896 | 9979-9982 | CC | denotes | and |
T5897 | 9983-9986 | DT | denotes | all |
T5898 | 9996-10004 | VBD | denotes | appeared |
T5899 | 9987-9989 | IN | denotes | of |
T5900 | 9990-9995 | DT | denotes | these |
T5901 | 10005-10011 | JJ | denotes | viable |
T5902 | 10011-10012 | . | denotes | . |
T5903 | 10012-10067 | sentence | denotes | At E13.5, 13 of 49 (27%) were mutant and two had died. |
T5904 | 10013-10015 | IN | denotes | At |
T5905 | 10038-10042 | VBD | denotes | were |
T5906 | 10016-10021 | NN | denotes | E13.5 |
T5907 | 10021-10023 | , | denotes | , |
T5908 | 10023-10025 | CD | denotes | 13 |
T5909 | 10029-10031 | CD | denotes | 49 |
T5910 | 10026-10028 | IN | denotes | of |
T5911 | 10032-10033 | -LRB- | denotes | ( |
T5912 | 10035-10036 | NN | denotes | % |
T5913 | 10033-10035 | CD | denotes | 27 |
T5914 | 10036-10037 | -RRB- | denotes | ) |
T5915 | 10043-10049 | JJ | denotes | mutant |
T5916 | 10050-10053 | CC | denotes | and |
T5917 | 10054-10057 | CD | denotes | two |
T5918 | 10062-10066 | VBN | denotes | died |
T5919 | 10058-10061 | VBD | denotes | had |
T5920 | 10066-10067 | . | denotes | . |
T5921 | 10067-10172 | sentence | denotes | At E15.5, 22 out of 91 (24%) were mutant and the majority of mutant embryos (17 out of the 22) had died. |
T5922 | 10068-10070 | IN | denotes | At |
T5923 | 10097-10101 | VBD | denotes | were |
T5924 | 10071-10076 | NN | denotes | E15.5 |
T5925 | 10076-10078 | , | denotes | , |
T5926 | 10078-10080 | CD | denotes | 22 |
T5927 | 10088-10090 | CD | denotes | 91 |
T5928 | 10081-10084 | IN | denotes | out |
T5929 | 10085-10087 | IN | denotes | of |
T5930 | 10091-10092 | -LRB- | denotes | ( |
T5931 | 10094-10095 | NN | denotes | % |
T5932 | 10092-10094 | CD | denotes | 24 |
T5933 | 10095-10096 | -RRB- | denotes | ) |
T5934 | 10102-10108 | JJ | denotes | mutant |
T5935 | 10109-10112 | CC | denotes | and |
T5936 | 10113-10116 | DT | denotes | the |
T5937 | 10117-10125 | NN | denotes | majority |
T5938 | 10167-10171 | VBN | denotes | died |
T5939 | 10126-10128 | IN | denotes | of |
T5940 | 10129-10135 | NN | denotes | mutant |
T5941 | 10136-10143 | NNS | denotes | embryos |
T5942 | 10144-10145 | -LRB- | denotes | ( |
T5943 | 10159-10161 | CD | denotes | 22 |
T5944 | 10145-10147 | CD | denotes | 17 |
T5945 | 10148-10151 | IN | denotes | out |
T5946 | 10152-10154 | IN | denotes | of |
T5947 | 10155-10158 | DT | denotes | the |
T5948 | 10161-10162 | -RRB- | denotes | ) |
T5949 | 10163-10166 | VBD | denotes | had |
T5950 | 10171-10172 | . | denotes | . |
T5951 | 10172-10278 | sentence | denotes | By E18.5, nine of 29 embryos (31%) were homozygous for the mutation, of which only one embryo was viable. |
T5952 | 10173-10175 | IN | denotes | By |
T5953 | 10208-10212 | VBD | denotes | were |
T5954 | 10176-10181 | NN | denotes | E18.5 |
T5955 | 10181-10183 | , | denotes | , |
T5956 | 10183-10187 | CD | denotes | nine |
T5957 | 10191-10193 | CD | denotes | 29 |
T5958 | 10188-10190 | IN | denotes | of |
T5959 | 10194-10201 | NNS | denotes | embryos |
T5960 | 10202-10203 | -LRB- | denotes | ( |
T5961 | 10205-10206 | NN | denotes | % |
T5962 | 10203-10205 | CD | denotes | 31 |
T5963 | 10206-10207 | -RRB- | denotes | ) |
T5964 | 10213-10223 | JJ | denotes | homozygous |
T5965 | 10224-10227 | IN | denotes | for |
T5966 | 10228-10231 | DT | denotes | the |
T5967 | 10232-10240 | NN | denotes | mutation |
T5968 | 10240-10242 | , | denotes | , |
T5969 | 10242-10244 | IN | denotes | of |
T5970 | 10267-10270 | VBD | denotes | was |
T5971 | 10245-10250 | WDT | denotes | which |
T5972 | 10251-10255 | RB | denotes | only |
T5973 | 10260-10266 | NN | denotes | embryo |
T5974 | 10256-10259 | CD | denotes | one |
T5975 | 10271-10277 | JJ | denotes | viable |
T5976 | 10277-10278 | . | denotes | . |
T5977 | 10278-10359 | sentence | denotes | Diaphragmatic muscularization was abnormal in all mutant mice examined (n > 25). |
T5978 | 10279-10292 | JJ | denotes | Diaphragmatic |
T5979 | 10293-10308 | NN | denotes | muscularization |
T5980 | 10309-10312 | VBD | denotes | was |
T5981 | 10313-10321 | JJ | denotes | abnormal |
T5982 | 10322-10324 | IN | denotes | in |
T5983 | 10325-10328 | DT | denotes | all |
T5984 | 10336-10340 | NNS | denotes | mice |
T5985 | 10329-10335 | NN | denotes | mutant |
T5986 | 10341-10349 | VBN | denotes | examined |
T5987 | 10350-10351 | -LRB- | denotes | ( |
T5988 | 10355-10357 | CD | denotes | 25 |
T5989 | 10351-10352 | NN | denotes | n |
T5990 | 10353-10354 | SYM | denotes | > |
T5991 | 10357-10358 | -RRB- | denotes | ) |
T5992 | 10358-10359 | . | denotes | . |
T5993 | 10359-10475 | sentence | denotes | Pulmonary hypoplasia was observed in 100% of mutants evaluated for that phenotype between E11.5 and birth (n > 50). |
T5994 | 10360-10369 | JJ | denotes | Pulmonary |
T5995 | 10370-10380 | NN | denotes | hypoplasia |
T5996 | 10385-10393 | VBN | denotes | observed |
T5997 | 10381-10384 | VBD | denotes | was |
T5998 | 10394-10396 | IN | denotes | in |
T5999 | 10397-10400 | CD | denotes | 100 |
T6000 | 10400-10401 | NN | denotes | % |
T6001 | 10402-10404 | IN | denotes | of |
T6002 | 10405-10412 | NNS | denotes | mutants |
T6003 | 10413-10422 | VBN | denotes | evaluated |
T6004 | 10423-10426 | IN | denotes | for |
T6005 | 10427-10431 | DT | denotes | that |
T6006 | 10432-10441 | NN | denotes | phenotype |
T6007 | 10442-10449 | IN | denotes | between |
T6008 | 10450-10455 | NN | denotes | E11.5 |
T6009 | 10456-10459 | CC | denotes | and |
T6010 | 10460-10465 | NN | denotes | birth |
T6011 | 10466-10467 | -LRB- | denotes | ( |
T6012 | 10471-10473 | CD | denotes | 50 |
T6013 | 10467-10468 | NN | denotes | n |
T6014 | 10469-10470 | SYM | denotes | > |
T6015 | 10473-10474 | -RRB- | denotes | ) |
T6016 | 10474-10475 | . | denotes | . |
T6017 | 10475-10733 | sentence | denotes | Examination of cardiac morphology showed that hearts from E15.5 lil mutant mice had a variety of developmental defects, including enlarged and abnormally developed endocardial cushions, a double-outlet right ventricle, and a complete atrioventricular canal. |
T6018 | 10476-10487 | NN | denotes | Examination |
T6019 | 10510-10516 | VBD | denotes | showed |
T6020 | 10488-10490 | IN | denotes | of |
T6021 | 10491-10498 | JJ | denotes | cardiac |
T6022 | 10499-10509 | NN | denotes | morphology |
T6023 | 10517-10521 | IN | denotes | that |
T6024 | 10556-10559 | VBD | denotes | had |
T6025 | 10522-10528 | NNS | denotes | hearts |
T6026 | 10529-10533 | IN | denotes | from |
T6027 | 10534-10539 | NN | denotes | E15.5 |
T6028 | 10551-10555 | NNS | denotes | mice |
T6029 | 10540-10543 | NN | denotes | lil |
T6030 | 10544-10550 | NN | denotes | mutant |
T6031 | 10560-10561 | DT | denotes | a |
T6032 | 10562-10569 | NN | denotes | variety |
T6033 | 10570-10572 | IN | denotes | of |
T6034 | 10573-10586 | JJ | denotes | developmental |
T6035 | 10587-10594 | NNS | denotes | defects |
T6036 | 10594-10596 | , | denotes | , |
T6037 | 10596-10605 | VBG | denotes | including |
T6038 | 10606-10614 | VBN | denotes | enlarged |
T6039 | 10652-10660 | NNS | denotes | cushions |
T6040 | 10615-10618 | CC | denotes | and |
T6041 | 10619-10629 | RB | denotes | abnormally |
T6042 | 10630-10639 | VBN | denotes | developed |
T6043 | 10640-10651 | JJ | denotes | endocardial |
T6044 | 10660-10662 | , | denotes | , |
T6045 | 10662-10663 | DT | denotes | a |
T6046 | 10684-10693 | NN | denotes | ventricle |
T6047 | 10664-10670 | JJ | denotes | double |
T6048 | 10671-10677 | NN | denotes | outlet |
T6049 | 10670-10671 | HYPH | denotes | - |
T6050 | 10678-10683 | JJ | denotes | right |
T6051 | 10693-10695 | , | denotes | , |
T6052 | 10695-10698 | CC | denotes | and |
T6053 | 10699-10700 | DT | denotes | a |
T6054 | 10727-10732 | NN | denotes | canal |
T6055 | 10701-10709 | JJ | denotes | complete |
T6056 | 10710-10726 | JJ | denotes | atrioventricular |
T6057 | 10732-10733 | . | denotes | . |
T6058 | 10733-10843 | sentence | denotes | The myocardium was also poorly developed, with thinning of the outer compact layer and decreased vascularity. |
T6059 | 10734-10737 | DT | denotes | The |
T6060 | 10738-10748 | NN | denotes | myocardium |
T6061 | 10749-10752 | VBD | denotes | was |
T6062 | 10753-10757 | RB | denotes | also |
T6063 | 10758-10764 | RB | denotes | poorly |
T6064 | 10765-10774 | VBN | denotes | developed |
T6065 | 10774-10776 | , | denotes | , |
T6066 | 10776-10780 | IN | denotes | with |
T6067 | 10781-10789 | NN | denotes | thinning |
T6068 | 10790-10792 | IN | denotes | of |
T6069 | 10793-10796 | DT | denotes | the |
T6070 | 10811-10816 | NN | denotes | layer |
T6071 | 10797-10802 | JJ | denotes | outer |
T6072 | 10803-10810 | JJ | denotes | compact |
T6073 | 10817-10820 | CC | denotes | and |
T6074 | 10821-10830 | VBN | denotes | decreased |
T6075 | 10831-10842 | NN | denotes | vascularity |
T6076 | 10842-10843 | . | denotes | . |
T6077 | 10843-11063 | sentence | denotes | The cohort of mutant mice that survived to birth also had cardiac malformations including atrioventricular-canal-type ventricular septal defects, ostium primum atrial septal defects, and enlarged atria (data not shown). |
T6078 | 10844-10847 | DT | denotes | The |
T6079 | 10848-10854 | NN | denotes | cohort |
T6080 | 10898-10901 | VBD | denotes | had |
T6081 | 10855-10857 | IN | denotes | of |
T6082 | 10858-10864 | NN | denotes | mutant |
T6083 | 10865-10869 | NNS | denotes | mice |
T6084 | 10870-10874 | WDT | denotes | that |
T6085 | 10875-10883 | VBD | denotes | survived |
T6086 | 10884-10886 | IN | denotes | to |
T6087 | 10887-10892 | NN | denotes | birth |
T6088 | 10893-10897 | RB | denotes | also |
T6089 | 10902-10909 | JJ | denotes | cardiac |
T6090 | 10910-10923 | NNS | denotes | malformations |
T6091 | 10924-10933 | VBG | denotes | including |
T6092 | 10934-10950 | JJ | denotes | atrioventricular |
T6093 | 10951-10956 | NN | denotes | canal |
T6094 | 10950-10951 | HYPH | denotes | - |
T6095 | 10957-10961 | NN | denotes | type |
T6096 | 10956-10957 | HYPH | denotes | - |
T6097 | 10981-10988 | NNS | denotes | defects |
T6098 | 10962-10973 | JJ | denotes | ventricular |
T6099 | 10974-10980 | JJ | denotes | septal |
T6100 | 10988-10990 | , | denotes | , |
T6101 | 10990-10996 | NN | denotes | ostium |
T6102 | 11018-11025 | NNS | denotes | defects |
T6103 | 10997-11003 | NN | denotes | primum |
T6104 | 11004-11010 | JJ | denotes | atrial |
T6105 | 11011-11017 | JJ | denotes | septal |
T6106 | 11025-11027 | , | denotes | , |
T6107 | 11027-11030 | CC | denotes | and |
T6108 | 11031-11039 | VBN | denotes | enlarged |
T6109 | 11040-11045 | NNS | denotes | atria |
T6110 | 11046-11047 | -LRB- | denotes | ( |
T6111 | 11056-11061 | VBN | denotes | shown |
T6112 | 11047-11051 | NNS | denotes | data |
T6113 | 11052-11055 | RB | denotes | not |
T6114 | 11061-11062 | -RRB- | denotes | ) |
T6115 | 11062-11063 | . | denotes | . |
T6116 | 11063-11165 | sentence | denotes | All mutants specifically evaluated for a cardiac phenotype (n = 10) had abnormal cardiac development. |
T6117 | 11064-11067 | DT | denotes | All |
T6118 | 11068-11075 | NNS | denotes | mutants |
T6119 | 11132-11135 | VBD | denotes | had |
T6120 | 11076-11088 | RB | denotes | specifically |
T6121 | 11089-11098 | VBN | denotes | evaluated |
T6122 | 11099-11102 | IN | denotes | for |
T6123 | 11103-11104 | DT | denotes | a |
T6124 | 11113-11122 | NN | denotes | phenotype |
T6125 | 11105-11112 | JJ | denotes | cardiac |
T6126 | 11123-11124 | -LRB- | denotes | ( |
T6127 | 11128-11130 | CD | denotes | 10 |
T6128 | 11124-11125 | NN | denotes | n |
T6129 | 11126-11127 | SYM | denotes | = |
T6130 | 11130-11131 | -RRB- | denotes | ) |
T6131 | 11136-11144 | JJ | denotes | abnormal |
T6132 | 11153-11164 | NN | denotes | development |
T6133 | 11145-11152 | JJ | denotes | cardiac |
T6134 | 11164-11165 | . | denotes | . |
T6135 | 11165-11320 | sentence | denotes | Examination of the 3-Mb region between D15Mit85 and D15Mit5 in DNA sequence databases revealed three predicted genes and four known genes, including Fog2. |
T6136 | 11166-11177 | NN | denotes | Examination |
T6137 | 11252-11260 | VBD | denotes | revealed |
T6138 | 11178-11180 | IN | denotes | of |
T6139 | 11181-11184 | DT | denotes | the |
T6140 | 11190-11196 | NN | denotes | region |
T6141 | 11185-11186 | CD | denotes | 3 |
T6142 | 11187-11189 | NN | denotes | Mb |
T6143 | 11186-11187 | HYPH | denotes | - |
T6144 | 11197-11204 | IN | denotes | between |
T6145 | 11205-11213 | NN | denotes | D15Mit85 |
T6146 | 11214-11217 | CC | denotes | and |
T6147 | 11218-11225 | NN | denotes | D15Mit5 |
T6148 | 11226-11228 | IN | denotes | in |
T6149 | 11229-11232 | NN | denotes | DNA |
T6150 | 11233-11241 | NN | denotes | sequence |
T6151 | 11242-11251 | NNS | denotes | databases |
T6152 | 11261-11266 | CD | denotes | three |
T6153 | 11277-11282 | NNS | denotes | genes |
T6154 | 11267-11276 | VBN | denotes | predicted |
T6155 | 11283-11286 | CC | denotes | and |
T6156 | 11287-11291 | CD | denotes | four |
T6157 | 11298-11303 | NNS | denotes | genes |
T6158 | 11292-11297 | JJ | denotes | known |
T6159 | 11303-11305 | , | denotes | , |
T6160 | 11305-11314 | VBG | denotes | including |
T6161 | 11315-11319 | NN | denotes | Fog2 |
T6162 | 11319-11320 | . | denotes | . |
T6163 | 11320-11530 | sentence | denotes | Targeted mutations of Fog2 have cardiac defects strikingly similar to those we identified in lil mutant mice, including atrioventricular canal defects, thinned myocardium, and absent coronary vasculature [16]. |
T6164 | 11321-11329 | VBN | denotes | Targeted |
T6165 | 11330-11339 | NNS | denotes | mutations |
T6166 | 11348-11352 | VBP | denotes | have |
T6167 | 11340-11342 | IN | denotes | of |
T6168 | 11343-11347 | NN | denotes | Fog2 |
T6169 | 11353-11360 | JJ | denotes | cardiac |
T6170 | 11361-11368 | NNS | denotes | defects |
T6171 | 11369-11379 | RB | denotes | strikingly |
T6172 | 11380-11387 | JJ | denotes | similar |
T6173 | 11388-11390 | IN | denotes | to |
T6174 | 11391-11396 | DT | denotes | those |
T6175 | 11397-11399 | PRP | denotes | we |
T6176 | 11400-11410 | VBD | denotes | identified |
T6177 | 11411-11413 | IN | denotes | in |
T6178 | 11414-11417 | NN | denotes | lil |
T6179 | 11425-11429 | NNS | denotes | mice |
T6180 | 11418-11424 | NN | denotes | mutant |
T6181 | 11429-11431 | , | denotes | , |
T6182 | 11431-11440 | VBG | denotes | including |
T6183 | 11441-11457 | JJ | denotes | atrioventricular |
T6184 | 11464-11471 | NNS | denotes | defects |
T6185 | 11458-11463 | NN | denotes | canal |
T6186 | 11471-11473 | , | denotes | , |
T6187 | 11473-11480 | VBN | denotes | thinned |
T6188 | 11481-11491 | NN | denotes | myocardium |
T6189 | 11491-11493 | , | denotes | , |
T6190 | 11493-11496 | CC | denotes | and |
T6191 | 11497-11503 | JJ | denotes | absent |
T6192 | 11513-11524 | NN | denotes | vasculature |
T6193 | 11504-11512 | JJ | denotes | coronary |
T6194 | 11525-11526 | -LRB- | denotes | [ |
T6195 | 11526-11528 | CD | denotes | 16 |
T6196 | 11528-11529 | -RRB- | denotes | ] |
T6197 | 11529-11530 | . | denotes | . |
T6198 | 11530-11672 | sentence | denotes | RT-PCR amplification of the proximal portion of Fog2 revealed longer transcripts in the lil mutant than in the wild-type embryos (Figure 2A). |
T6199 | 11531-11533 | NN | denotes | RT |
T6200 | 11534-11537 | NN | denotes | PCR |
T6201 | 11533-11534 | HYPH | denotes | - |
T6202 | 11538-11551 | NN | denotes | amplification |
T6203 | 11584-11592 | VBD | denotes | revealed |
T6204 | 11552-11554 | IN | denotes | of |
T6205 | 11555-11558 | DT | denotes | the |
T6206 | 11568-11575 | NN | denotes | portion |
T6207 | 11559-11567 | JJ | denotes | proximal |
T6208 | 11576-11578 | IN | denotes | of |
T6209 | 11579-11583 | NN | denotes | Fog2 |
T6210 | 11593-11599 | JJR | denotes | longer |
T6211 | 11600-11611 | NNS | denotes | transcripts |
T6212 | 11612-11614 | IN | denotes | in |
T6213 | 11615-11618 | DT | denotes | the |
T6214 | 11623-11629 | NN | denotes | mutant |
T6215 | 11619-11622 | NN | denotes | lil |
T6216 | 11630-11634 | IN | denotes | than |
T6217 | 11635-11637 | IN | denotes | in |
T6218 | 11638-11641 | DT | denotes | the |
T6219 | 11647-11651 | NN | denotes | type |
T6220 | 11642-11646 | JJ | denotes | wild |
T6221 | 11646-11647 | HYPH | denotes | - |
T6222 | 11652-11659 | NNS | denotes | embryos |
T6223 | 11660-11661 | -LRB- | denotes | ( |
T6224 | 11661-11667 | NN | denotes | Figure |
T6225 | 11668-11670 | CD | denotes | 2A |
T6226 | 11670-11671 | -RRB- | denotes | ) |
T6227 | 11671-11672 | . | denotes | . |
T6228 | 11672-11850 | sentence | denotes | Sequencing of the mutant transcript revealed a point mutation (from thymine to cytosine) 2 bp after position 301, which is in the splice donor site at the end of the third exon. |
T6229 | 11673-11683 | NN | denotes | Sequencing |
T6230 | 11709-11717 | VBD | denotes | revealed |
T6231 | 11684-11686 | IN | denotes | of |
T6232 | 11687-11690 | DT | denotes | the |
T6233 | 11698-11708 | NN | denotes | transcript |
T6234 | 11691-11697 | NN | denotes | mutant |
T6235 | 11718-11719 | DT | denotes | a |
T6236 | 11726-11734 | NN | denotes | mutation |
T6237 | 11720-11725 | NN | denotes | point |
T6238 | 11735-11736 | -LRB- | denotes | ( |
T6239 | 11736-11740 | IN | denotes | from |
T6240 | 11741-11748 | NN | denotes | thymine |
T6241 | 11749-11751 | IN | denotes | to |
T6242 | 11752-11760 | NN | denotes | cytosine |
T6243 | 11760-11761 | -RRB- | denotes | ) |
T6244 | 11762-11763 | CD | denotes | 2 |
T6245 | 11764-11766 | NN | denotes | bp |
T6246 | 11767-11772 | IN | denotes | after |
T6247 | 11773-11781 | NN | denotes | position |
T6248 | 11782-11785 | CD | denotes | 301 |
T6249 | 11785-11787 | , | denotes | , |
T6250 | 11787-11792 | WDT | denotes | which |
T6251 | 11793-11795 | VBZ | denotes | is |
T6252 | 11796-11798 | IN | denotes | in |
T6253 | 11799-11802 | DT | denotes | the |
T6254 | 11816-11820 | NN | denotes | site |
T6255 | 11803-11809 | NN | denotes | splice |
T6256 | 11810-11815 | NN | denotes | donor |
T6257 | 11821-11823 | IN | denotes | at |
T6258 | 11824-11827 | DT | denotes | the |
T6259 | 11828-11831 | NN | denotes | end |
T6260 | 11832-11834 | IN | denotes | of |
T6261 | 11835-11838 | DT | denotes | the |
T6262 | 11845-11849 | NN | denotes | exon |
T6263 | 11839-11844 | JJ | denotes | third |
T6264 | 11849-11850 | . | denotes | . |
T6265 | 11850-12070 | sentence | denotes | This mutation causes a splicing defect that results in the insertion of 85 bp of intronic sequence into the mutant transcript, and introduces a stop codon that generates a severely truncated protein product (Figure 2B). |
T6266 | 11851-11855 | DT | denotes | This |
T6267 | 11856-11864 | NN | denotes | mutation |
T6268 | 11865-11871 | VBZ | denotes | causes |
T6269 | 11872-11873 | DT | denotes | a |
T6270 | 11883-11889 | NN | denotes | defect |
T6271 | 11874-11882 | NN | denotes | splicing |
T6272 | 11890-11894 | WDT | denotes | that |
T6273 | 11895-11902 | VBZ | denotes | results |
T6274 | 11903-11905 | IN | denotes | in |
T6275 | 11906-11909 | DT | denotes | the |
T6276 | 11910-11919 | NN | denotes | insertion |
T6277 | 11920-11922 | IN | denotes | of |
T6278 | 11923-11925 | CD | denotes | 85 |
T6279 | 11926-11928 | NN | denotes | bp |
T6280 | 11929-11931 | IN | denotes | of |
T6281 | 11932-11940 | JJ | denotes | intronic |
T6282 | 11941-11949 | NN | denotes | sequence |
T6283 | 11950-11954 | IN | denotes | into |
T6284 | 11955-11958 | DT | denotes | the |
T6285 | 11966-11976 | NN | denotes | transcript |
T6286 | 11959-11965 | NN | denotes | mutant |
T6287 | 11976-11978 | , | denotes | , |
T6288 | 11978-11981 | CC | denotes | and |
T6289 | 11982-11992 | VBZ | denotes | introduces |
T6290 | 11993-11994 | DT | denotes | a |
T6291 | 12000-12005 | NN | denotes | codon |
T6292 | 11995-11999 | NN | denotes | stop |
T6293 | 12006-12010 | WDT | denotes | that |
T6294 | 12011-12020 | VBZ | denotes | generates |
T6295 | 12021-12022 | DT | denotes | a |
T6296 | 12050-12057 | NN | denotes | product |
T6297 | 12023-12031 | RB | denotes | severely |
T6298 | 12032-12041 | VBN | denotes | truncated |
T6299 | 12042-12049 | NN | denotes | protein |
T6300 | 12058-12059 | -LRB- | denotes | ( |
T6301 | 12059-12065 | NN | denotes | Figure |
T6302 | 12066-12068 | CD | denotes | 2B |
T6303 | 12068-12069 | -RRB- | denotes | ) |
T6304 | 12069-12070 | . | denotes | . |
T6305 | 12070-12183 | sentence | denotes | Heterozygous lil mutant mice were crossed with a Fog2 +/− (null allele) mutant generated by gene targeting [16]. |
T6306 | 12071-12083 | JJ | denotes | Heterozygous |
T6307 | 12095-12099 | NNS | denotes | mice |
T6308 | 12084-12087 | NN | denotes | lil |
T6309 | 12088-12094 | NN | denotes | mutant |
T6310 | 12105-12112 | VBN | denotes | crossed |
T6311 | 12100-12104 | VBD | denotes | were |
T6312 | 12113-12117 | IN | denotes | with |
T6313 | 12118-12119 | DT | denotes | a |
T6314 | 12143-12149 | NN | denotes | mutant |
T6315 | 12120-12124 | NN | denotes | Fog2 |
T6316 | 12125-12126 | SYM | denotes | + |
T6317 | 12126-12127 | HYPH | denotes | / |
T6318 | 12127-12128 | SYM | denotes | − |
T6319 | 12129-12130 | -LRB- | denotes | ( |
T6320 | 12135-12141 | NN | denotes | allele |
T6321 | 12130-12134 | JJ | denotes | null |
T6322 | 12141-12142 | -RRB- | denotes | ) |
T6323 | 12150-12159 | VBN | denotes | generated |
T6324 | 12160-12162 | IN | denotes | by |
T6325 | 12163-12167 | NN | denotes | gene |
T6326 | 12168-12177 | NN | denotes | targeting |
T6327 | 12178-12179 | -LRB- | denotes | [ |
T6328 | 12179-12181 | CD | denotes | 16 |
T6329 | 12181-12182 | -RRB- | denotes | ] |
T6330 | 12182-12183 | . | denotes | . |
T6331 | 12183-12309 | sentence | denotes | Doubly heterozygous mice had an embryonic lethal phenotype; this failure to complement proves that lil is a mutation in Fog2. |
T6332 | 12184-12190 | RB | denotes | Doubly |
T6333 | 12191-12203 | JJ | denotes | heterozygous |
T6334 | 12204-12208 | NNS | denotes | mice |
T6335 | 12209-12212 | VBD | denotes | had |
T6336 | 12271-12277 | VBZ | denotes | proves |
T6337 | 12213-12215 | DT | denotes | an |
T6338 | 12233-12242 | NN | denotes | phenotype |
T6339 | 12216-12225 | JJ | denotes | embryonic |
T6340 | 12226-12232 | JJ | denotes | lethal |
T6341 | 12242-12243 | : | denotes | ; |
T6342 | 12244-12248 | DT | denotes | this |
T6343 | 12249-12256 | NN | denotes | failure |
T6344 | 12257-12259 | TO | denotes | to |
T6345 | 12260-12270 | VB | denotes | complement |
T6346 | 12278-12282 | IN | denotes | that |
T6347 | 12287-12289 | VBZ | denotes | is |
T6348 | 12283-12286 | NN | denotes | lil |
T6349 | 12290-12291 | DT | denotes | a |
T6350 | 12292-12300 | NN | denotes | mutation |
T6351 | 12301-12303 | IN | denotes | in |
T6352 | 12304-12308 | NN | denotes | Fog2 |
T6353 | 12308-12309 | . | denotes | . |
T6354 | 12309-12512 | sentence | denotes | The variable phenotype of lil mice (relative to that found for the Fog2 null mutant) is likely due to the generation of a low level of normal transcript despite the presence of the splice site mutation. |
T6355 | 12310-12313 | DT | denotes | The |
T6356 | 12323-12332 | NN | denotes | phenotype |
T6357 | 12314-12322 | JJ | denotes | variable |
T6358 | 12395-12397 | VBZ | denotes | is |
T6359 | 12333-12335 | IN | denotes | of |
T6360 | 12336-12339 | NN | denotes | lil |
T6361 | 12340-12344 | NNS | denotes | mice |
T6362 | 12345-12346 | -LRB- | denotes | ( |
T6363 | 12346-12354 | JJ | denotes | relative |
T6364 | 12355-12357 | IN | denotes | to |
T6365 | 12358-12362 | DT | denotes | that |
T6366 | 12363-12368 | VBN | denotes | found |
T6367 | 12369-12372 | IN | denotes | for |
T6368 | 12373-12376 | DT | denotes | the |
T6369 | 12387-12393 | NN | denotes | mutant |
T6370 | 12377-12381 | NN | denotes | Fog2 |
T6371 | 12382-12386 | JJ | denotes | null |
T6372 | 12393-12394 | -RRB- | denotes | ) |
T6373 | 12398-12404 | RB | denotes | likely |
T6374 | 12405-12408 | IN | denotes | due |
T6375 | 12409-12411 | IN | denotes | to |
T6376 | 12412-12415 | DT | denotes | the |
T6377 | 12416-12426 | NN | denotes | generation |
T6378 | 12427-12429 | IN | denotes | of |
T6379 | 12430-12431 | DT | denotes | a |
T6380 | 12436-12441 | NN | denotes | level |
T6381 | 12432-12435 | JJ | denotes | low |
T6382 | 12442-12444 | IN | denotes | of |
T6383 | 12445-12451 | JJ | denotes | normal |
T6384 | 12452-12462 | NN | denotes | transcript |
T6385 | 12463-12470 | IN | denotes | despite |
T6386 | 12471-12474 | DT | denotes | the |
T6387 | 12475-12483 | NN | denotes | presence |
T6388 | 12484-12486 | IN | denotes | of |
T6389 | 12487-12490 | DT | denotes | the |
T6390 | 12503-12511 | NN | denotes | mutation |
T6391 | 12491-12497 | NN | denotes | splice |
T6392 | 12498-12502 | NN | denotes | site |
T6393 | 12511-12512 | . | denotes | . |
T8822 | 17580-17584 | DT | denotes | this |
T8121 | 12938-12942 | NN | denotes | Lung |
T8122 | 12957-12968 | NN | denotes | Development |
T8123 | 12943-12946 | CC | denotes | and |
T8124 | 12947-12956 | NN | denotes | Diaphragm |
T8125 | 12969-12971 | IN | denotes | in |
T8126 | 12972-12975 | DT | denotes | the |
T8127 | 12988-12993 | NN | denotes | Mouse |
T8128 | 12976-12980 | NN | denotes | Fog2 |
T8129 | 12981-12987 | NN | denotes | Mutant |
T8130 | 12993-13093 | sentence | denotes | Experiments were conducted to evaluate the role of Fog2 in pulmonary and diaphragmatic development. |
T8131 | 12994-13005 | NNS | denotes | Experiments |
T8132 | 13011-13020 | VBN | denotes | conducted |
T8133 | 13006-13010 | VBD | denotes | were |
T8134 | 13021-13023 | TO | denotes | to |
T8135 | 13024-13032 | VB | denotes | evaluate |
T8136 | 13033-13036 | DT | denotes | the |
T8137 | 13037-13041 | NN | denotes | role |
T8138 | 13042-13044 | IN | denotes | of |
T8139 | 13045-13049 | NN | denotes | Fog2 |
T8140 | 13050-13052 | IN | denotes | in |
T8141 | 13053-13062 | JJ | denotes | pulmonary |
T8142 | 13081-13092 | NN | denotes | development |
T8143 | 13063-13066 | CC | denotes | and |
T8144 | 13067-13080 | JJ | denotes | diaphragmatic |
T8145 | 13092-13093 | . | denotes | . |
T8146 | 13093-13236 | sentence | denotes | The pulmonary phenotype is characterized by diffuse hypoplasia and specific loss of the accessory lobe and a portion of the right middle lobe. |
T8147 | 13094-13097 | DT | denotes | The |
T8148 | 13108-13117 | NN | denotes | phenotype |
T8149 | 13098-13107 | JJ | denotes | pulmonary |
T8150 | 13121-13134 | VBN | denotes | characterized |
T8151 | 13118-13120 | VBZ | denotes | is |
T8152 | 13135-13137 | IN | denotes | by |
T8153 | 13138-13145 | JJ | denotes | diffuse |
T8154 | 13146-13156 | NN | denotes | hypoplasia |
T8155 | 13157-13160 | CC | denotes | and |
T8156 | 13161-13169 | JJ | denotes | specific |
T8157 | 13170-13174 | NN | denotes | loss |
T8158 | 13175-13177 | IN | denotes | of |
T8159 | 13178-13181 | DT | denotes | the |
T8160 | 13192-13196 | NN | denotes | lobe |
T8161 | 13182-13191 | JJ | denotes | accessory |
T8162 | 13197-13200 | CC | denotes | and |
T8163 | 13201-13202 | DT | denotes | a |
T8164 | 13203-13210 | NN | denotes | portion |
T8165 | 13211-13213 | IN | denotes | of |
T8166 | 13214-13217 | DT | denotes | the |
T8167 | 13231-13235 | NN | denotes | lobe |
T8168 | 13218-13223 | JJ | denotes | right |
T8169 | 13224-13230 | JJ | denotes | middle |
T8170 | 13235-13236 | . | denotes | . |
T8171 | 13236-13466 | sentence | denotes | It is well established that abnormalities in either diaphragmatic development or fetal breathing can result in a secondary pulmonary hypoplasia, although loss of normal structure has never been documented in this context [17,18]. |
T8172 | 13237-13239 | PRP | denotes | It |
T8173 | 13240-13242 | VBZ | denotes | is |
T8174 | 13243-13247 | RB | denotes | well |
T8175 | 13248-13259 | VBN | denotes | established |
T8176 | 13260-13264 | IN | denotes | that |
T8177 | 13338-13344 | VB | denotes | result |
T8178 | 13265-13278 | NNS | denotes | abnormalities |
T8179 | 13279-13281 | IN | denotes | in |
T8180 | 13282-13288 | CC | denotes | either |
T8181 | 13303-13314 | NN | denotes | development |
T8182 | 13289-13302 | JJ | denotes | diaphragmatic |
T8183 | 13315-13317 | CC | denotes | or |
T8184 | 13318-13323 | JJ | denotes | fetal |
T8185 | 13324-13333 | NN | denotes | breathing |
T8186 | 13334-13337 | MD | denotes | can |
T8187 | 13345-13347 | IN | denotes | in |
T8188 | 13348-13349 | DT | denotes | a |
T8189 | 13370-13380 | NN | denotes | hypoplasia |
T8190 | 13350-13359 | JJ | denotes | secondary |
T8191 | 13360-13369 | JJ | denotes | pulmonary |
T8192 | 13380-13382 | , | denotes | , |
T8193 | 13382-13390 | IN | denotes | although |
T8194 | 13431-13441 | VBN | denotes | documented |
T8195 | 13391-13395 | NN | denotes | loss |
T8196 | 13396-13398 | IN | denotes | of |
T8197 | 13399-13405 | JJ | denotes | normal |
T8198 | 13406-13415 | NN | denotes | structure |
T8199 | 13416-13419 | VBZ | denotes | has |
T8200 | 13420-13425 | RB | denotes | never |
T8201 | 13426-13430 | VBN | denotes | been |
T8202 | 13442-13444 | IN | denotes | in |
T8203 | 13445-13449 | DT | denotes | this |
T8204 | 13450-13457 | NN | denotes | context |
T8205 | 13458-13459 | -LRB- | denotes | [ |
T8206 | 13462-13464 | CD | denotes | 18 |
T8207 | 13459-13461 | CD | denotes | 17 |
T8208 | 13461-13462 | , | denotes | , |
T8209 | 13464-13465 | -RRB- | denotes | ] |
T8210 | 13465-13466 | . | denotes | . |
T8211 | 13466-13672 | sentence | denotes | Fog2 is expressed diffusely in the pulmonary mesenchyme during the period of branching morphogenesis, while later expression is restricted to the smooth muscles of airways and pulmonary vessels (Figure 3). |
T8212 | 13467-13471 | NN | denotes | Fog2 |
T8213 | 13475-13484 | VBN | denotes | expressed |
T8214 | 13472-13474 | VBZ | denotes | is |
T8215 | 13485-13494 | RB | denotes | diffusely |
T8216 | 13495-13497 | IN | denotes | in |
T8217 | 13498-13501 | DT | denotes | the |
T8218 | 13512-13522 | NN | denotes | mesenchyme |
T8219 | 13502-13511 | JJ | denotes | pulmonary |
T8220 | 13523-13529 | IN | denotes | during |
T8221 | 13530-13533 | DT | denotes | the |
T8222 | 13534-13540 | NN | denotes | period |
T8223 | 13541-13543 | IN | denotes | of |
T8224 | 13544-13553 | NN | denotes | branching |
T8225 | 13554-13567 | NN | denotes | morphogenesis |
T8226 | 13567-13569 | , | denotes | , |
T8227 | 13569-13574 | IN | denotes | while |
T8228 | 13595-13605 | VBN | denotes | restricted |
T8229 | 13575-13580 | JJ | denotes | later |
T8230 | 13581-13591 | NN | denotes | expression |
T8231 | 13592-13594 | VBZ | denotes | is |
T8232 | 13606-13608 | IN | denotes | to |
T8233 | 13609-13612 | DT | denotes | the |
T8234 | 13620-13627 | NNS | denotes | muscles |
T8235 | 13613-13619 | JJ | denotes | smooth |
T8236 | 13628-13630 | IN | denotes | of |
T8237 | 13631-13638 | NNS | denotes | airways |
T8238 | 13639-13642 | CC | denotes | and |
T8239 | 13643-13652 | JJ | denotes | pulmonary |
T8240 | 13653-13660 | NNS | denotes | vessels |
T8241 | 13661-13662 | -LRB- | denotes | ( |
T8242 | 13662-13668 | NN | denotes | Figure |
T8243 | 13669-13670 | CD | denotes | 3 |
T8244 | 13670-13671 | -RRB- | denotes | ) |
T8245 | 13671-13672 | . | denotes | . |
T8246 | 13672-13898 | sentence | denotes | This, and the observation that lungs appeared small on transverse sections evaluated prior to diaphragmatic muscularization or function, suggests that the pulmonary hypoplasia occurs independently of the diaphragmatic defect. |
T8247 | 13673-13677 | DT | denotes | This |
T8248 | 13810-13818 | VBZ | denotes | suggests |
T8249 | 13677-13679 | , | denotes | , |
T8250 | 13679-13682 | CC | denotes | and |
T8251 | 13683-13686 | DT | denotes | the |
T8252 | 13687-13698 | NN | denotes | observation |
T8253 | 13699-13703 | IN | denotes | that |
T8254 | 13710-13718 | VBD | denotes | appeared |
T8255 | 13704-13709 | NNS | denotes | lungs |
T8256 | 13719-13724 | JJ | denotes | small |
T8257 | 13725-13727 | IN | denotes | on |
T8258 | 13728-13738 | JJ | denotes | transverse |
T8259 | 13739-13747 | NNS | denotes | sections |
T8260 | 13748-13757 | VBN | denotes | evaluated |
T8261 | 13758-13763 | JJ | denotes | prior |
T8262 | 13764-13766 | IN | denotes | to |
T8263 | 13767-13780 | JJ | denotes | diaphragmatic |
T8264 | 13781-13796 | NN | denotes | muscularization |
T8265 | 13797-13799 | CC | denotes | or |
T8266 | 13800-13808 | NN | denotes | function |
T8267 | 13808-13810 | , | denotes | , |
T8268 | 13819-13823 | IN | denotes | that |
T8269 | 13849-13855 | VBZ | denotes | occurs |
T8270 | 13824-13827 | DT | denotes | the |
T8271 | 13838-13848 | NN | denotes | hypoplasia |
T8272 | 13828-13837 | JJ | denotes | pulmonary |
T8273 | 13856-13869 | RB | denotes | independently |
T8274 | 13870-13872 | IN | denotes | of |
T8275 | 13873-13876 | DT | denotes | the |
T8276 | 13891-13897 | NN | denotes | defect |
T8277 | 13877-13890 | JJ | denotes | diaphragmatic |
T8278 | 13897-13898 | . | denotes | . |
T8279 | 13898-14035 | sentence | denotes | To test this hypothesis, lungs were dissected from Fog2 −/− mice and littermate controls before the onset of fetal diaphragmatic motion. |
T8280 | 13899-13901 | TO | denotes | To |
T8281 | 13902-13906 | VB | denotes | test |
T8282 | 13935-13944 | VBN | denotes | dissected |
T8283 | 13907-13911 | DT | denotes | this |
T8284 | 13912-13922 | NN | denotes | hypothesis |
T8285 | 13922-13924 | , | denotes | , |
T8286 | 13924-13929 | NNS | denotes | lungs |
T8287 | 13930-13934 | VBD | denotes | were |
T8288 | 13945-13949 | IN | denotes | from |
T8289 | 13950-13954 | NN | denotes | Fog2 |
T8290 | 13959-13963 | NNS | denotes | mice |
T8291 | 13955-13956 | SYM | denotes | − |
T8292 | 13956-13957 | HYPH | denotes | / |
T8293 | 13957-13958 | SYM | denotes | − |
T8294 | 13964-13967 | CC | denotes | and |
T8295 | 13968-13978 | NN | denotes | littermate |
T8296 | 13979-13987 | NNS | denotes | controls |
T8297 | 13988-13994 | IN | denotes | before |
T8298 | 13995-13998 | DT | denotes | the |
T8299 | 13999-14004 | NN | denotes | onset |
T8300 | 14005-14007 | IN | denotes | of |
T8301 | 14008-14013 | JJ | denotes | fetal |
T8302 | 14028-14034 | NN | denotes | motion |
T8303 | 14014-14027 | JJ | denotes | diaphragmatic |
T8304 | 14034-14035 | . | denotes | . |
T8305 | 14035-14167 | sentence | denotes | Fog2 −/− mice were used for this experiment, as we wanted to avoid potential phenotypic variance from the lil hypomorphic mutation. |
T8306 | 14036-14040 | NN | denotes | Fog2 |
T8307 | 14045-14049 | NNS | denotes | mice |
T8308 | 14041-14042 | SYM | denotes | − |
T8309 | 14042-14043 | HYPH | denotes | / |
T8310 | 14043-14044 | SYM | denotes | − |
T8311 | 14055-14059 | VBN | denotes | used |
T8312 | 14050-14054 | VBD | denotes | were |
T8313 | 14060-14063 | IN | denotes | for |
T8314 | 14064-14068 | DT | denotes | this |
T8315 | 14069-14079 | NN | denotes | experiment |
T8316 | 14079-14081 | , | denotes | , |
T8317 | 14081-14083 | IN | denotes | as |
T8318 | 14087-14093 | VBD | denotes | wanted |
T8319 | 14084-14086 | PRP | denotes | we |
T8320 | 14094-14096 | TO | denotes | to |
T8321 | 14097-14102 | VB | denotes | avoid |
T8322 | 14103-14112 | JJ | denotes | potential |
T8323 | 14124-14132 | NN | denotes | variance |
T8324 | 14113-14123 | JJ | denotes | phenotypic |
T8325 | 14133-14137 | IN | denotes | from |
T8326 | 14138-14141 | DT | denotes | the |
T8327 | 14158-14166 | NN | denotes | mutation |
T8328 | 14142-14145 | NN | denotes | lil |
T8329 | 14146-14157 | JJ | denotes | hypomorphic |
T8330 | 14166-14167 | . | denotes | . |
T8331 | 14167-14282 | sentence | denotes | Lungs dissected at E12 from Fog2 −/− embryos were smaller in size and lacked the development of an accessory lobe. |
T8332 | 14168-14173 | NNS | denotes | Lungs |
T8333 | 14213-14217 | VBD | denotes | were |
T8334 | 14174-14183 | VBN | denotes | dissected |
T8335 | 14184-14186 | IN | denotes | at |
T8336 | 14187-14190 | NN | denotes | E12 |
T8337 | 14191-14195 | IN | denotes | from |
T8338 | 14196-14200 | NN | denotes | Fog2 |
T8339 | 14205-14212 | NNS | denotes | embryos |
T8340 | 14201-14202 | SYM | denotes | − |
T8341 | 14202-14203 | HYPH | denotes | / |
T8342 | 14203-14204 | SYM | denotes | − |
T8343 | 14218-14225 | JJR | denotes | smaller |
T8344 | 14226-14228 | IN | denotes | in |
T8345 | 14229-14233 | NN | denotes | size |
T8346 | 14234-14237 | CC | denotes | and |
T8347 | 14238-14244 | VBD | denotes | lacked |
T8348 | 14245-14248 | DT | denotes | the |
T8349 | 14249-14260 | NN | denotes | development |
T8350 | 14261-14263 | IN | denotes | of |
T8351 | 14264-14266 | DT | denotes | an |
T8352 | 14277-14281 | NN | denotes | lobe |
T8353 | 14267-14276 | JJ | denotes | accessory |
T8354 | 14281-14282 | . | denotes | . |
T8355 | 14282-14497 | sentence | denotes | In 11 viable Fog2− /− lung culture explants, there was never development of an accessory lobe, and the weights of mutant lungs cultured for 5 d were significantly lower than those of littermate controls (Figure 4). |
T8356 | 14283-14285 | IN | denotes | In |
T8357 | 14334-14337 | VBD | denotes | was |
T8358 | 14286-14288 | CD | denotes | 11 |
T8359 | 14318-14326 | NNS | denotes | explants |
T8360 | 14289-14295 | JJ | denotes | viable |
T8361 | 14296-14300 | NN | denotes | Fog2 |
T8362 | 14300-14301 | SYM | denotes | − |
T8363 | 14302-14303 | HYPH | denotes | / |
T8364 | 14303-14304 | SYM | denotes | − |
T8365 | 14305-14309 | NN | denotes | lung |
T8366 | 14310-14317 | NN | denotes | culture |
T8367 | 14326-14328 | , | denotes | , |
T8368 | 14328-14333 | EX | denotes | there |
T8369 | 14338-14343 | RB | denotes | never |
T8370 | 14344-14355 | NN | denotes | development |
T8371 | 14356-14358 | IN | denotes | of |
T8372 | 14359-14361 | DT | denotes | an |
T8373 | 14372-14376 | NN | denotes | lobe |
T8374 | 14362-14371 | JJ | denotes | accessory |
T8375 | 14376-14378 | , | denotes | , |
T8376 | 14378-14381 | CC | denotes | and |
T8377 | 14382-14385 | DT | denotes | the |
T8378 | 14386-14393 | NNS | denotes | weights |
T8379 | 14427-14431 | VBD | denotes | were |
T8380 | 14394-14396 | IN | denotes | of |
T8381 | 14397-14403 | NN | denotes | mutant |
T8382 | 14404-14409 | NNS | denotes | lungs |
T8383 | 14410-14418 | VBN | denotes | cultured |
T8384 | 14419-14422 | IN | denotes | for |
T8385 | 14423-14424 | CD | denotes | 5 |
T8386 | 14425-14426 | NN | denotes | d |
T8387 | 14432-14445 | RB | denotes | significantly |
T8388 | 14446-14451 | JJR | denotes | lower |
T8389 | 14452-14456 | IN | denotes | than |
T8390 | 14457-14462 | DT | denotes | those |
T8391 | 14463-14465 | IN | denotes | of |
T8392 | 14466-14476 | NN | denotes | littermate |
T8393 | 14477-14485 | NNS | denotes | controls |
T8394 | 14486-14487 | -LRB- | denotes | ( |
T8395 | 14487-14493 | NN | denotes | Figure |
T8396 | 14494-14495 | CD | denotes | 4 |
T8397 | 14495-14496 | -RRB- | denotes | ) |
T8398 | 14496-14497 | . | denotes | . |
T8399 | 14497-14591 | sentence | denotes | These data demonstrate that the pulmonary hypoplasia in Fog2 mutant mice is a primary defect. |
T8400 | 14498-14503 | DT | denotes | These |
T8401 | 14504-14508 | NNS | denotes | data |
T8402 | 14509-14520 | VBP | denotes | demonstrate |
T8403 | 14521-14525 | IN | denotes | that |
T8404 | 14571-14573 | VBZ | denotes | is |
T8405 | 14526-14529 | DT | denotes | the |
T8406 | 14540-14550 | NN | denotes | hypoplasia |
T8407 | 14530-14539 | JJ | denotes | pulmonary |
T8408 | 14551-14553 | IN | denotes | in |
T8409 | 14554-14558 | NN | denotes | Fog2 |
T8410 | 14566-14570 | NNS | denotes | mice |
T8411 | 14559-14565 | NN | denotes | mutant |
T8412 | 14574-14575 | DT | denotes | a |
T8413 | 14584-14590 | NN | denotes | defect |
T8414 | 14576-14583 | JJ | denotes | primary |
T8415 | 14590-14591 | . | denotes | . |
T8416 | 14591-15375 | sentence | denotes | Figure 3 Fog2 Is Expressed in the Developing Lung and Diaphragm Fog2 is expressed in the diffuse pulmonary mesenchyme at E13.5 (A) (arrow shows mesenchyme) and is restricted to the bronchial and vascular smooth muscle (sm) at E16.5 (B). Fog2 is expressed diffusely in the developing diaphragm (Dia) both prior to (E11.5) (C) and after muscularization (E13.5) (D). Figure 4 Fog2 Is Necessary for Primary Lung Development Fog2 null lungs removed prior to diaphragmatic muscularization and grown in vitro show no accessory lobe development. Accessory lobe is labeled with black arrow in control littermate lungs. Branching in the unaffected lobes appeared to be delayed by 6–12 h, but all mutants developed an intricate branching pattern in the unaffected lobes after culture for 5 d. |
T8417 | 15204-15213 | NN | denotes | Branching |
T8418 | 15238-15246 | VBD | denotes | appeared |
T8419 | 15214-15216 | IN | denotes | in |
T8420 | 15217-15220 | DT | denotes | the |
T8421 | 15232-15237 | NNS | denotes | lobes |
T8422 | 15221-15231 | JJ | denotes | unaffected |
T8423 | 15247-15249 | TO | denotes | to |
T8424 | 15253-15260 | VBN | denotes | delayed |
T8425 | 15250-15252 | VB | denotes | be |
T8426 | 15261-15263 | IN | denotes | by |
T8427 | 15264-15265 | CD | denotes | 6 |
T8428 | 15266-15268 | CD | denotes | 12 |
T8429 | 15265-15266 | SYM | denotes | – |
T8430 | 15269-15270 | NN | denotes | h |
T8431 | 15270-15272 | , | denotes | , |
T8432 | 15272-15275 | CC | denotes | but |
T8433 | 15276-15279 | DT | denotes | all |
T8434 | 15280-15287 | NNS | denotes | mutants |
T8435 | 15288-15297 | VBD | denotes | developed |
T8436 | 15298-15300 | DT | denotes | an |
T8437 | 15321-15328 | NN | denotes | pattern |
T8438 | 15301-15310 | JJ | denotes | intricate |
T8439 | 15311-15320 | NN | denotes | branching |
T8440 | 15329-15331 | IN | denotes | in |
T8441 | 15332-15335 | DT | denotes | the |
T8442 | 15347-15352 | NNS | denotes | lobes |
T8443 | 15336-15346 | JJ | denotes | unaffected |
T8444 | 15353-15358 | IN | denotes | after |
T8445 | 15359-15366 | NN | denotes | culture |
T8446 | 15367-15370 | IN | denotes | for |
T8447 | 15371-15372 | CD | denotes | 5 |
T8448 | 15373-15374 | NN | denotes | d |
T8449 | 15374-15375 | . | denotes | . |
T8450 | 15375-15641 | sentence | denotes | Because the Fog2 phenotype is striking for specific lobar loss, the spatial pattern of Fog2 expression was evaluated in normal embryos during the period of early lobar establishment to determine whether Fog2 expression is specifically different at these lobar buds. |
T8451 | 15376-15383 | IN | denotes | Because |
T8452 | 15403-15405 | VBZ | denotes | is |
T8453 | 15384-15387 | DT | denotes | the |
T8454 | 15393-15402 | NN | denotes | phenotype |
T8455 | 15388-15392 | NN | denotes | Fog2 |
T8456 | 15483-15492 | VBN | denotes | evaluated |
T8457 | 15406-15414 | JJ | denotes | striking |
T8458 | 15415-15418 | IN | denotes | for |
T8459 | 15419-15427 | JJ | denotes | specific |
T8460 | 15434-15438 | NN | denotes | loss |
T8461 | 15428-15433 | NN | denotes | lobar |
T8462 | 15438-15440 | , | denotes | , |
T8463 | 15440-15443 | DT | denotes | the |
T8464 | 15452-15459 | NN | denotes | pattern |
T8465 | 15444-15451 | JJ | denotes | spatial |
T8466 | 15460-15462 | IN | denotes | of |
T8467 | 15463-15467 | NN | denotes | Fog2 |
T8468 | 15468-15478 | NN | denotes | expression |
T8469 | 15479-15482 | VBD | denotes | was |
T8470 | 15493-15495 | IN | denotes | in |
T8471 | 15496-15502 | JJ | denotes | normal |
T8472 | 15503-15510 | NNS | denotes | embryos |
T8473 | 15511-15517 | IN | denotes | during |
T8474 | 15518-15521 | DT | denotes | the |
T8475 | 15522-15528 | NN | denotes | period |
T8476 | 15529-15531 | IN | denotes | of |
T8477 | 15532-15537 | JJ | denotes | early |
T8478 | 15544-15557 | NN | denotes | establishment |
T8479 | 15538-15543 | NN | denotes | lobar |
T8480 | 15558-15560 | TO | denotes | to |
T8481 | 15561-15570 | VB | denotes | determine |
T8482 | 15571-15578 | IN | denotes | whether |
T8483 | 15595-15597 | VBZ | denotes | is |
T8484 | 15579-15583 | NN | denotes | Fog2 |
T8485 | 15584-15594 | NN | denotes | expression |
T8486 | 15598-15610 | RB | denotes | specifically |
T8487 | 15611-15620 | JJ | denotes | different |
T8488 | 15621-15623 | IN | denotes | at |
T8489 | 15624-15629 | DT | denotes | these |
T8490 | 15636-15640 | NNS | denotes | buds |
T8491 | 15630-15635 | NN | denotes | lobar |
T8492 | 15640-15641 | . | denotes | . |
T8493 | 15641-15761 | sentence | denotes | Expression was evaluated in mice carrying a lacZ gene incorporated into the Fog2 locus (S. Tevosian, unpublished data). |
T8494 | 15642-15652 | NN | denotes | Expression |
T8495 | 15657-15666 | VBN | denotes | evaluated |
T8496 | 15653-15656 | VBD | denotes | was |
T8497 | 15667-15669 | IN | denotes | in |
T8498 | 15670-15674 | NNS | denotes | mice |
T8499 | 15675-15683 | VBG | denotes | carrying |
T8500 | 15684-15685 | DT | denotes | a |
T8501 | 15691-15695 | NN | denotes | gene |
T8502 | 15686-15690 | NN | denotes | lacZ |
T8503 | 15696-15708 | VBN | denotes | incorporated |
T8504 | 15709-15713 | IN | denotes | into |
T8505 | 15714-15717 | DT | denotes | the |
T8506 | 15723-15728 | NN | denotes | locus |
T8507 | 15718-15722 | NN | denotes | Fog2 |
T8508 | 15729-15730 | -LRB- | denotes | ( |
T8509 | 15730-15732 | NNP | denotes | S. |
T8510 | 15733-15741 | NNP | denotes | Tevosian |
T8511 | 15741-15743 | , | denotes | , |
T8512 | 15743-15754 | JJ | denotes | unpublished |
T8513 | 15755-15759 | NNS | denotes | data |
T8514 | 15759-15760 | -RRB- | denotes | ) |
T8515 | 15760-15761 | . | denotes | . |
T8516 | 15761-16012 | sentence | denotes | In nine mice examined at E11.5, all lungs showed a specific enhancement of Fog2 expression in the mesenchyme surrounding the accessory bud and the right middle lobe bud, which are the lobes that do not develop normally in Fog2 mutant mice (Figure 5). |
T8517 | 15762-15764 | IN | denotes | In |
T8518 | 15804-15810 | VBD | denotes | showed |
T8519 | 15765-15769 | CD | denotes | nine |
T8520 | 15770-15774 | NNS | denotes | mice |
T8521 | 15775-15783 | VBN | denotes | examined |
T8522 | 15784-15786 | IN | denotes | at |
T8523 | 15787-15792 | NN | denotes | E11.5 |
T8524 | 15792-15794 | , | denotes | , |
T8525 | 15794-15797 | DT | denotes | all |
T8526 | 15798-15803 | NNS | denotes | lungs |
T8527 | 15811-15812 | DT | denotes | a |
T8528 | 15822-15833 | NN | denotes | enhancement |
T8529 | 15813-15821 | JJ | denotes | specific |
T8530 | 15834-15836 | IN | denotes | of |
T8531 | 15837-15841 | NN | denotes | Fog2 |
T8532 | 15842-15852 | NN | denotes | expression |
T8533 | 15853-15855 | IN | denotes | in |
T8534 | 15856-15859 | DT | denotes | the |
T8535 | 15860-15870 | NN | denotes | mesenchyme |
T8536 | 15871-15882 | VBG | denotes | surrounding |
T8537 | 15883-15886 | DT | denotes | the |
T8538 | 15897-15900 | NN | denotes | bud |
T8539 | 15887-15896 | JJ | denotes | accessory |
T8540 | 15901-15904 | CC | denotes | and |
T8541 | 15905-15908 | DT | denotes | the |
T8542 | 15927-15930 | NN | denotes | bud |
T8543 | 15909-15914 | JJ | denotes | right |
T8544 | 15915-15921 | JJ | denotes | middle |
T8545 | 15922-15926 | NN | denotes | lobe |
T8546 | 15930-15932 | , | denotes | , |
T8547 | 15932-15937 | WDT | denotes | which |
T8548 | 15938-15941 | VBP | denotes | are |
T8549 | 15942-15945 | DT | denotes | the |
T8550 | 15946-15951 | NNS | denotes | lobes |
T8551 | 15952-15956 | WDT | denotes | that |
T8552 | 15964-15971 | VB | denotes | develop |
T8553 | 15957-15959 | VBP | denotes | do |
T8554 | 15960-15963 | RB | denotes | not |
T8555 | 15972-15980 | RB | denotes | normally |
T8556 | 15981-15983 | IN | denotes | in |
T8557 | 15984-15988 | NN | denotes | Fog2 |
T8558 | 15996-16000 | NNS | denotes | mice |
T8559 | 15989-15995 | NN | denotes | mutant |
T8560 | 16001-16002 | -LRB- | denotes | ( |
T8561 | 16002-16008 | NN | denotes | Figure |
T8562 | 16009-16010 | CD | denotes | 5 |
T8563 | 16010-16011 | -RRB- | denotes | ) |
T8564 | 16011-16012 | . | denotes | . |
T8565 | 16012-16144 | sentence | denotes | By E12.5, expression was diffuse in the pulmonary mesenchyme, as was seen previously with in situ hybridization on tissue sections. |
T8566 | 16013-16015 | IN | denotes | By |
T8567 | 16034-16037 | VBD | denotes | was |
T8568 | 16016-16021 | NN | denotes | E12.5 |
T8569 | 16021-16023 | , | denotes | , |
T8570 | 16023-16033 | NN | denotes | expression |
T8571 | 16038-16045 | JJ | denotes | diffuse |
T8572 | 16046-16048 | IN | denotes | in |
T8573 | 16049-16052 | DT | denotes | the |
T8574 | 16063-16073 | NN | denotes | mesenchyme |
T8575 | 16053-16062 | JJ | denotes | pulmonary |
T8576 | 16073-16075 | , | denotes | , |
T8577 | 16075-16077 | IN | denotes | as |
T8578 | 16082-16086 | VBN | denotes | seen |
T8579 | 16078-16081 | VBD | denotes | was |
T8580 | 16087-16097 | RB | denotes | previously |
T8581 | 16098-16102 | IN | denotes | with |
T8582 | 16103-16105 | FW | denotes | in |
T8583 | 16106-16110 | FW | denotes | situ |
T8584 | 16111-16124 | NN | denotes | hybridization |
T8585 | 16125-16127 | IN | denotes | on |
T8586 | 16128-16134 | NN | denotes | tissue |
T8587 | 16135-16143 | NNS | denotes | sections |
T8588 | 16143-16144 | . | denotes | . |
T8589 | 16144-16526 | sentence | denotes | Figure 5 Fog2 Expression in Embryonic Non-Mutant Lungs In embryonic non-mutant lungs, Fog2 is most highly expressed at the tips of the accessory (single arrows) and right middle lobes (double arrows) at E11.25 (A) and E11.75 (B), while expression is diffuse by E12.75 (C). Diaphragms from Fog2 lil mice show an intact membrane with a defect in muscular patterning (see Figure 1B). |
T8590 | 16419-16429 | NNS | denotes | Diaphragms |
T8591 | 16449-16453 | VBP | denotes | show |
T8592 | 16430-16434 | IN | denotes | from |
T8593 | 16435-16439 | NN | denotes | Fog2 |
T8594 | 16444-16448 | NNS | denotes | mice |
T8595 | 16440-16443 | NN | denotes | lil |
T8596 | 16454-16456 | DT | denotes | an |
T8597 | 16464-16472 | NN | denotes | membrane |
T8598 | 16457-16463 | JJ | denotes | intact |
T8599 | 16473-16477 | IN | denotes | with |
T8600 | 16478-16479 | DT | denotes | a |
T8601 | 16480-16486 | NN | denotes | defect |
T8602 | 16487-16489 | IN | denotes | in |
T8603 | 16490-16498 | JJ | denotes | muscular |
T8604 | 16499-16509 | NN | denotes | patterning |
T8605 | 16510-16511 | -LRB- | denotes | ( |
T8606 | 16511-16514 | VB | denotes | see |
T8607 | 16515-16521 | NN | denotes | Figure |
T8608 | 16522-16524 | CD | denotes | 1B |
T8609 | 16524-16525 | -RRB- | denotes | ) |
T8610 | 16525-16526 | . | denotes | . |
T8611 | 16526-16661 | sentence | denotes | The membranous portion of the diaphragm is populated by a migratory population of muscle precursor cells, much like the limbs [19,20]. |
T8612 | 16527-16530 | DT | denotes | The |
T8613 | 16542-16549 | NN | denotes | portion |
T8614 | 16531-16541 | JJ | denotes | membranous |
T8615 | 16570-16579 | VBN | denotes | populated |
T8616 | 16550-16552 | IN | denotes | of |
T8617 | 16553-16556 | DT | denotes | the |
T8618 | 16557-16566 | NN | denotes | diaphragm |
T8619 | 16567-16569 | VBZ | denotes | is |
T8620 | 16580-16582 | IN | denotes | by |
T8621 | 16583-16584 | DT | denotes | a |
T8622 | 16595-16605 | NN | denotes | population |
T8623 | 16585-16594 | JJ | denotes | migratory |
T8624 | 16606-16608 | IN | denotes | of |
T8625 | 16609-16615 | NN | denotes | muscle |
T8626 | 16626-16631 | NNS | denotes | cells |
T8627 | 16616-16625 | NN | denotes | precursor |
T8628 | 16631-16633 | , | denotes | , |
T8629 | 16633-16637 | RB | denotes | much |
T8630 | 16638-16642 | IN | denotes | like |
T8631 | 16643-16646 | DT | denotes | the |
T8632 | 16647-16652 | NNS | denotes | limbs |
T8633 | 16653-16654 | -LRB- | denotes | [ |
T8634 | 16657-16659 | CD | denotes | 20 |
T8635 | 16654-16656 | CD | denotes | 19 |
T8636 | 16656-16657 | , | denotes | , |
T8637 | 16659-16660 | -RRB- | denotes | ] |
T8638 | 16660-16661 | . | denotes | . |
T8639 | 16661-16791 | sentence | denotes | Mice with defects in genes known to be important for the control of this process have intact but amuscular diaphragms [17,21,22]. |
T8640 | 16662-16666 | NNS | denotes | Mice |
T8641 | 16743-16747 | VBP | denotes | have |
T8642 | 16667-16671 | IN | denotes | with |
T8643 | 16672-16679 | NNS | denotes | defects |
T8644 | 16680-16682 | IN | denotes | in |
T8645 | 16683-16688 | NNS | denotes | genes |
T8646 | 16689-16694 | VBN | denotes | known |
T8647 | 16695-16697 | TO | denotes | to |
T8648 | 16698-16700 | VB | denotes | be |
T8649 | 16701-16710 | JJ | denotes | important |
T8650 | 16711-16714 | IN | denotes | for |
T8651 | 16715-16718 | DT | denotes | the |
T8652 | 16719-16726 | NN | denotes | control |
T8653 | 16727-16729 | IN | denotes | of |
T8654 | 16730-16734 | DT | denotes | this |
T8655 | 16735-16742 | NN | denotes | process |
T8656 | 16748-16754 | JJ | denotes | intact |
T8657 | 16769-16779 | NNS | denotes | diaphragms |
T8658 | 16755-16758 | CC | denotes | but |
T8659 | 16759-16768 | JJ | denotes | amuscular |
T8660 | 16780-16781 | -LRB- | denotes | [ |
T8661 | 16787-16789 | CD | denotes | 22 |
T8662 | 16781-16783 | CD | denotes | 17 |
T8663 | 16783-16784 | , | denotes | , |
T8664 | 16784-16786 | CD | denotes | 21 |
T8665 | 16786-16787 | , | denotes | , |
T8666 | 16789-16790 | -RRB- | denotes | ] |
T8667 | 16790-16791 | . | denotes | . |
T8668 | 16791-16943 | sentence | denotes | Hepatocyte growth factor/Scatter factor (HGF) is one potential candidate responsible for the guidance of muscle precursors to the membranous diaphragm. |
T8669 | 16792-16802 | NN | denotes | Hepatocyte |
T8670 | 16810-16816 | NN | denotes | factor |
T8671 | 16803-16809 | NN | denotes | growth |
T8672 | 16838-16840 | VBZ | denotes | is |
T8673 | 16816-16817 | HYPH | denotes | / |
T8674 | 16817-16824 | NN | denotes | Scatter |
T8675 | 16825-16831 | NN | denotes | factor |
T8676 | 16832-16833 | -LRB- | denotes | ( |
T8677 | 16833-16836 | NN | denotes | HGF |
T8678 | 16836-16837 | -RRB- | denotes | ) |
T8679 | 16841-16844 | CD | denotes | one |
T8680 | 16855-16864 | NN | denotes | candidate |
T8681 | 16845-16854 | JJ | denotes | potential |
T8682 | 16865-16876 | JJ | denotes | responsible |
T8683 | 16877-16880 | IN | denotes | for |
T8684 | 16881-16884 | DT | denotes | the |
T8685 | 16885-16893 | NN | denotes | guidance |
T8686 | 16894-16896 | IN | denotes | of |
T8687 | 16897-16903 | NN | denotes | muscle |
T8688 | 16904-16914 | NNS | denotes | precursors |
T8689 | 16915-16917 | IN | denotes | to |
T8690 | 16918-16921 | DT | denotes | the |
T8691 | 16933-16942 | NN | denotes | diaphragm |
T8692 | 16922-16932 | JJ | denotes | membranous |
T8693 | 16942-16943 | . | denotes | . |
T8694 | 16943-17166 | sentence | denotes | It has been shown that HGF is expressed along this anatomic pathway [23], and mice with absence of the HGF receptor c-Met fail to form muscularized pleuroperitoneal folds (PPFs), and thus have amuscular diaphragms [24,25]. |
T8695 | 16944-16946 | PRP | denotes | It |
T8696 | 16956-16961 | VBN | denotes | shown |
T8697 | 16947-16950 | VBZ | denotes | has |
T8698 | 16951-16955 | VBN | denotes | been |
T8699 | 16962-16966 | IN | denotes | that |
T8700 | 16974-16983 | VBN | denotes | expressed |
T8701 | 16967-16970 | NN | denotes | HGF |
T8702 | 16971-16973 | VBZ | denotes | is |
T8703 | 16984-16989 | IN | denotes | along |
T8704 | 16990-16994 | DT | denotes | this |
T8705 | 17004-17011 | NN | denotes | pathway |
T8706 | 16995-17003 | JJ | denotes | anatomic |
T8707 | 17012-17013 | -LRB- | denotes | [ |
T8708 | 17013-17015 | CD | denotes | 23 |
T8709 | 17015-17016 | -RRB- | denotes | ] |
T8710 | 17016-17018 | , | denotes | , |
T8711 | 17018-17021 | CC | denotes | and |
T8712 | 17022-17026 | NNS | denotes | mice |
T8713 | 17066-17070 | VBP | denotes | fail |
T8714 | 17027-17031 | IN | denotes | with |
T8715 | 17032-17039 | NN | denotes | absence |
T8716 | 17040-17042 | IN | denotes | of |
T8717 | 17043-17046 | DT | denotes | the |
T8718 | 17051-17059 | NN | denotes | receptor |
T8719 | 17047-17050 | NN | denotes | HGF |
T8720 | 17060-17061 | NN | denotes | c |
T8721 | 17062-17065 | NN | denotes | Met |
T8722 | 17061-17062 | HYPH | denotes | - |
T8723 | 17071-17073 | TO | denotes | to |
T8724 | 17074-17078 | VB | denotes | form |
T8725 | 17079-17091 | VBN | denotes | muscularized |
T8726 | 17109-17114 | NNS | denotes | folds |
T8727 | 17092-17108 | JJ | denotes | pleuroperitoneal |
T8728 | 17115-17116 | -LRB- | denotes | ( |
T8729 | 17116-17120 | NNS | denotes | PPFs |
T8730 | 17120-17121 | -RRB- | denotes | ) |
T8731 | 17121-17123 | , | denotes | , |
T8732 | 17123-17126 | CC | denotes | and |
T8733 | 17127-17131 | RB | denotes | thus |
T8734 | 17132-17136 | VBP | denotes | have |
T8735 | 17137-17146 | JJ | denotes | amuscular |
T8736 | 17147-17157 | NNS | denotes | diaphragms |
T8737 | 17158-17159 | -LRB- | denotes | [ |
T8738 | 17162-17164 | CD | denotes | 25 |
T8739 | 17159-17161 | CD | denotes | 24 |
T8740 | 17161-17162 | , | denotes | , |
T8741 | 17164-17165 | -RRB- | denotes | ] |
T8742 | 17165-17166 | . | denotes | . |
T8743 | 17166-17307 | sentence | denotes | Fog2 is expressed diffusely in the early amuscular diaphragm at E11.5 as well as in the later muscularized diaphragm (see Figure 3C and 3D). |
T8744 | 17167-17171 | NN | denotes | Fog2 |
T8745 | 17175-17184 | VBN | denotes | expressed |
T8746 | 17172-17174 | VBZ | denotes | is |
T8747 | 17185-17194 | RB | denotes | diffusely |
T8748 | 17195-17197 | IN | denotes | in |
T8749 | 17198-17201 | DT | denotes | the |
T8750 | 17218-17227 | NN | denotes | diaphragm |
T8751 | 17202-17207 | JJ | denotes | early |
T8752 | 17208-17217 | JJ | denotes | amuscular |
T8753 | 17228-17230 | IN | denotes | at |
T8754 | 17231-17236 | NN | denotes | E11.5 |
T8755 | 17237-17239 | RB | denotes | as |
T8756 | 17245-17247 | IN | denotes | as |
T8757 | 17240-17244 | RB | denotes | well |
T8758 | 17248-17250 | IN | denotes | in |
T8759 | 17251-17254 | DT | denotes | the |
T8760 | 17274-17283 | NN | denotes | diaphragm |
T8761 | 17255-17260 | JJ | denotes | later |
T8762 | 17261-17273 | VBN | denotes | muscularized |
T8763 | 17284-17285 | -LRB- | denotes | ( |
T8764 | 17285-17288 | VB | denotes | see |
T8765 | 17289-17295 | NN | denotes | Figure |
T8766 | 17296-17298 | CD | denotes | 3C |
T8767 | 17299-17302 | CC | denotes | and |
T8768 | 17303-17305 | CD | denotes | 3D |
T8769 | 17305-17306 | -RRB- | denotes | ) |
T8770 | 17306-17307 | . | denotes | . |
T8771 | 17307-17482 | sentence | denotes | Pax3 and MyoD, transcription factors required for appropriate migration and determination of myogenic precursors, were detected in the PPFs of Fog2 lil mice (data not shown). |
T8772 | 17308-17312 | NN | denotes | Pax3 |
T8773 | 17427-17435 | VBN | denotes | detected |
T8774 | 17313-17316 | CC | denotes | and |
T8775 | 17317-17321 | NN | denotes | MyoD |
T8776 | 17321-17323 | , | denotes | , |
T8777 | 17323-17336 | NN | denotes | transcription |
T8778 | 17337-17344 | NNS | denotes | factors |
T8779 | 17345-17353 | VBN | denotes | required |
T8780 | 17354-17357 | IN | denotes | for |
T8781 | 17358-17369 | JJ | denotes | appropriate |
T8782 | 17370-17379 | NN | denotes | migration |
T8783 | 17380-17383 | CC | denotes | and |
T8784 | 17384-17397 | NN | denotes | determination |
T8785 | 17398-17400 | IN | denotes | of |
T8786 | 17401-17409 | JJ | denotes | myogenic |
T8787 | 17410-17420 | NNS | denotes | precursors |
T8788 | 17420-17422 | , | denotes | , |
T8789 | 17422-17426 | VBD | denotes | were |
T8790 | 17436-17438 | IN | denotes | in |
T8791 | 17439-17442 | DT | denotes | the |
T8792 | 17443-17447 | NNS | denotes | PPFs |
T8793 | 17448-17450 | IN | denotes | of |
T8794 | 17451-17455 | NN | denotes | Fog2 |
T8795 | 17460-17464 | NNS | denotes | mice |
T8796 | 17456-17459 | NN | denotes | lil |
T8797 | 17465-17466 | -LRB- | denotes | ( |
T8798 | 17475-17480 | VBN | denotes | shown |
T8799 | 17466-17470 | NNS | denotes | data |
T8800 | 17471-17474 | RB | denotes | not |
T8801 | 17480-17481 | -RRB- | denotes | ) |
T8802 | 17481-17482 | . | denotes | . |
T8803 | 17482-17678 | sentence | denotes | However, in situ expression analysis demonstrated that the expression of HGF in the region where this structure meets the membranous diaphragm was markedly reduced in Fog2 mutant mice (Figure 6). |
T8804 | 17483-17490 | RB | denotes | However |
T8805 | 17520-17532 | VBD | denotes | demonstrated |
T8806 | 17490-17492 | , | denotes | , |
T8807 | 17492-17494 | FW | denotes | in |
T8808 | 17495-17499 | FW | denotes | situ |
T8809 | 17511-17519 | NN | denotes | analysis |
T8810 | 17500-17510 | NN | denotes | expression |
T8811 | 17533-17537 | IN | denotes | that |
T8812 | 17639-17646 | VBN | denotes | reduced |
T8813 | 17538-17541 | DT | denotes | the |
T8814 | 17542-17552 | NN | denotes | expression |
T8815 | 17553-17555 | IN | denotes | of |
T8816 | 17556-17559 | NN | denotes | HGF |
T8817 | 17560-17562 | IN | denotes | in |
T8818 | 17563-17566 | DT | denotes | the |
T8819 | 17567-17573 | NN | denotes | region |
T8820 | 17574-17579 | WRB | denotes | where |
T8821 | 17595-17600 | VBZ | denotes | meets |
T8823 | 17585-17594 | NN | denotes | structure |
T8824 | 17601-17604 | DT | denotes | the |
T8825 | 17616-17625 | NN | denotes | diaphragm |
T8826 | 17605-17615 | JJ | denotes | membranous |
T8827 | 17626-17629 | VBD | denotes | was |
T8828 | 17630-17638 | RB | denotes | markedly |
T8829 | 17647-17649 | IN | denotes | in |
T8830 | 17650-17654 | NN | denotes | Fog2 |
T8831 | 17662-17666 | NNS | denotes | mice |
T8832 | 17655-17661 | NN | denotes | mutant |
T8833 | 17667-17668 | -LRB- | denotes | ( |
T8834 | 17668-17674 | NN | denotes | Figure |
T8835 | 17675-17676 | CD | denotes | 6 |
T8836 | 17676-17677 | -RRB- | denotes | ) |
T8837 | 17677-17678 | . | denotes | . |
T8838 | 17678-17972 | sentence | denotes | We hypothesize that Fog2 is required (either directly or indirectly) for the induction of HGF in the developing diaphragm, and dysregulation of HGF patterning along the path of muscle precursor cell migration between the PPF and the diaphragm accounts for the abnormal phenotype in these mice. |
T8839 | 17679-17681 | PRP | denotes | We |
T8840 | 17682-17693 | VBP | denotes | hypothesize |
T8841 | 17694-17698 | IN | denotes | that |
T8842 | 17707-17715 | VBN | denotes | required |
T8843 | 17699-17703 | NN | denotes | Fog2 |
T8844 | 17704-17706 | VBZ | denotes | is |
T8845 | 17716-17717 | -LRB- | denotes | ( |
T8846 | 17717-17723 | CC | denotes | either |
T8847 | 17724-17732 | RB | denotes | directly |
T8848 | 17733-17735 | CC | denotes | or |
T8849 | 17736-17746 | RB | denotes | indirectly |
T8850 | 17746-17747 | -RRB- | denotes | ) |
T8851 | 17748-17751 | IN | denotes | for |
T8852 | 17752-17755 | DT | denotes | the |
T8853 | 17756-17765 | NN | denotes | induction |
T8854 | 17766-17768 | IN | denotes | of |
T8855 | 17769-17772 | NN | denotes | HGF |
T8856 | 17773-17775 | IN | denotes | in |
T8857 | 17776-17779 | DT | denotes | the |
T8858 | 17791-17800 | NN | denotes | diaphragm |
T8859 | 17780-17790 | VBG | denotes | developing |
T8860 | 17800-17802 | , | denotes | , |
T8861 | 17802-17805 | CC | denotes | and |
T8862 | 17806-17819 | NN | denotes | dysregulation |
T8863 | 17922-17930 | VBZ | denotes | accounts |
T8864 | 17820-17822 | IN | denotes | of |
T8865 | 17823-17826 | NN | denotes | HGF |
T8866 | 17827-17837 | NN | denotes | patterning |
T8867 | 17838-17843 | IN | denotes | along |
T8868 | 17844-17847 | DT | denotes | the |
T8869 | 17848-17852 | NN | denotes | path |
T8870 | 17853-17855 | IN | denotes | of |
T8871 | 17856-17862 | NN | denotes | muscle |
T8872 | 17873-17877 | NN | denotes | cell |
T8873 | 17863-17872 | NN | denotes | precursor |
T8874 | 17878-17887 | NN | denotes | migration |
T8875 | 17888-17895 | IN | denotes | between |
T8876 | 17896-17899 | DT | denotes | the |
T8877 | 17900-17903 | NN | denotes | PPF |
T8878 | 17904-17907 | CC | denotes | and |
T8879 | 17908-17911 | DT | denotes | the |
T8880 | 17912-17921 | NN | denotes | diaphragm |
T8881 | 17931-17934 | IN | denotes | for |
T8882 | 17935-17938 | DT | denotes | the |
T8883 | 17948-17957 | NN | denotes | phenotype |
T8884 | 17939-17947 | JJ | denotes | abnormal |
T8885 | 17958-17960 | IN | denotes | in |
T8886 | 17961-17966 | DT | denotes | these |
T8887 | 17967-17971 | NNS | denotes | mice |
T8888 | 17971-17972 | . | denotes | . |
T9907 | 18221-18225 | NN | denotes | FOG2 |
T9908 | 18226-18234 | NN | denotes | Mutation |
T9909 | 18235-18237 | IN | denotes | in |
T9910 | 18238-18239 | DT | denotes | a |
T9911 | 18240-18247 | NN | denotes | Patient |
T9912 | 18248-18252 | IN | denotes | with |
T9913 | 18253-18262 | NN | denotes | Diaphragm |
T9914 | 18272-18285 | NNS | denotes | Abnormalities |
T9915 | 18263-18266 | CC | denotes | and |
T9916 | 18267-18271 | NN | denotes | Lung |
T9917 | 18285-18509 | sentence | denotes | FOG2 sequence analysis was performed on autopsy tissue from 30 of 32 deceased children with an anatomic diagnosis of diaphragmatic defect evaluated at the Children's Hospital in Boston, Massachusetts, between 1993 and 2003. |
T9918 | 18286-18290 | NN | denotes | FOG2 |
T9919 | 18300-18308 | NN | denotes | analysis |
T9920 | 18291-18299 | NN | denotes | sequence |
T9921 | 18313-18322 | VBN | denotes | performed |
T9922 | 18309-18312 | VBD | denotes | was |
T9923 | 18323-18325 | IN | denotes | on |
T9924 | 18326-18333 | NN | denotes | autopsy |
T9925 | 18334-18340 | NN | denotes | tissue |
T9926 | 18341-18345 | IN | denotes | from |
T9927 | 18346-18348 | CD | denotes | 30 |
T9928 | 18352-18354 | CD | denotes | 32 |
T9929 | 18349-18351 | IN | denotes | of |
T9930 | 18364-18372 | NNS | denotes | children |
T9931 | 18355-18363 | VBN | denotes | deceased |
T9932 | 18373-18377 | IN | denotes | with |
T9933 | 18378-18380 | DT | denotes | an |
T9934 | 18390-18399 | NN | denotes | diagnosis |
T9935 | 18381-18389 | JJ | denotes | anatomic |
T9936 | 18400-18402 | IN | denotes | of |
T9937 | 18403-18416 | JJ | denotes | diaphragmatic |
T9938 | 18417-18423 | NN | denotes | defect |
T9939 | 18424-18433 | VBN | denotes | evaluated |
T9940 | 18434-18436 | IN | denotes | at |
T9941 | 18437-18440 | DT | denotes | the |
T9942 | 18452-18460 | NNP | denotes | Hospital |
T9943 | 18441-18449 | NNPS | denotes | Children |
T9944 | 18449-18451 | POS | denotes | 's |
T9945 | 18461-18463 | IN | denotes | in |
T9946 | 18464-18470 | NNP | denotes | Boston |
T9947 | 18470-18472 | , | denotes | , |
T9948 | 18472-18485 | NNP | denotes | Massachusetts |
T9949 | 18485-18487 | , | denotes | , |
T9950 | 18487-18494 | IN | denotes | between |
T9951 | 18495-18499 | CD | denotes | 1993 |
T9952 | 18500-18503 | CC | denotes | and |
T9953 | 18504-18508 | CD | denotes | 2003 |
T9954 | 18508-18509 | . | denotes | . |
T9955 | 18509-18576 | sentence | denotes | Autopsy reports were reviewed to determine the specific diagnoses. |
T9956 | 18510-18517 | NN | denotes | Autopsy |
T9957 | 18518-18525 | NNS | denotes | reports |
T9958 | 18531-18539 | VBN | denotes | reviewed |
T9959 | 18526-18530 | VBD | denotes | were |
T9960 | 18540-18542 | TO | denotes | to |
T9961 | 18543-18552 | VB | denotes | determine |
T9962 | 18553-18556 | DT | denotes | the |
T9963 | 18566-18575 | NNS | denotes | diagnoses |
T9964 | 18557-18565 | JJ | denotes | specific |
T9965 | 18575-18576 | . | denotes | . |
T9966 | 18576-18838 | sentence | denotes | Of these 30 cases, 17 (57%) had Bochdalek CDH, two (7%) had diaphragmatic agenesis, seven (23%) had diaphragmatic eventration/muscularization defects (without Bochdalek CDH), and four (13%) had Bochdalek hernia of one hemidiaphragm and eventration of the other. |
T9967 | 18577-18579 | IN | denotes | Of |
T9968 | 18605-18608 | VBD | denotes | had |
T9969 | 18580-18585 | DT | denotes | these |
T9970 | 18589-18594 | NNS | denotes | cases |
T9971 | 18586-18588 | CD | denotes | 30 |
T9972 | 18594-18596 | , | denotes | , |
T9973 | 18596-18598 | CD | denotes | 17 |
T9974 | 18599-18600 | -LRB- | denotes | ( |
T9975 | 18602-18603 | NN | denotes | % |
T9976 | 18600-18602 | CD | denotes | 57 |
T9977 | 18603-18604 | -RRB- | denotes | ) |
T9978 | 18609-18618 | NNP | denotes | Bochdalek |
T9979 | 18619-18622 | NN | denotes | CDH |
T9980 | 18622-18624 | , | denotes | , |
T9981 | 18624-18627 | CD | denotes | two |
T9982 | 18633-18636 | VBD | denotes | had |
T9983 | 18628-18629 | -LRB- | denotes | ( |
T9984 | 18630-18631 | NN | denotes | % |
T9985 | 18629-18630 | CD | denotes | 7 |
T9986 | 18631-18632 | -RRB- | denotes | ) |
T9987 | 18637-18650 | JJ | denotes | diaphragmatic |
T9988 | 18651-18659 | NN | denotes | agenesis |
T9989 | 18659-18661 | , | denotes | , |
T9990 | 18661-18666 | CD | denotes | seven |
T9991 | 18673-18676 | VBD | denotes | had |
T9992 | 18667-18668 | -LRB- | denotes | ( |
T9993 | 18670-18671 | NN | denotes | % |
T9994 | 18668-18670 | CD | denotes | 23 |
T9995 | 18671-18672 | -RRB- | denotes | ) |
T9996 | 18677-18690 | JJ | denotes | diaphragmatic |
T9997 | 18691-18702 | NN | denotes | eventration |
T9998 | 18702-18703 | HYPH | denotes | / |
T9999 | 18703-18718 | NN | denotes | muscularization |
T10000 | 18719-18726 | NNS | denotes | defects |
T10001 | 18727-18728 | -LRB- | denotes | ( |
T10002 | 18728-18735 | IN | denotes | without |
T10003 | 18736-18745 | NNP | denotes | Bochdalek |
T10004 | 18746-18749 | NN | denotes | CDH |
T10005 | 18749-18750 | -RRB- | denotes | ) |
T10006 | 18750-18752 | , | denotes | , |
T10007 | 18752-18755 | CC | denotes | and |
T10008 | 18756-18760 | CD | denotes | four |
T10009 | 18767-18770 | VBD | denotes | had |
T10010 | 18761-18762 | -LRB- | denotes | ( |
T10011 | 18764-18765 | NN | denotes | % |
T10012 | 18762-18764 | CD | denotes | 13 |
T10013 | 18765-18766 | -RRB- | denotes | ) |
T10014 | 18771-18780 | NNP | denotes | Bochdalek |
T10015 | 18781-18787 | NN | denotes | hernia |
T10016 | 18788-18790 | IN | denotes | of |
T10017 | 18791-18794 | CD | denotes | one |
T10018 | 18795-18808 | NN | denotes | hemidiaphragm |
T10019 | 18809-18812 | CC | denotes | and |
T10020 | 18813-18824 | NN | denotes | eventration |
T10021 | 18825-18827 | IN | denotes | of |
T10022 | 18828-18831 | DT | denotes | the |
T10023 | 18832-18837 | NN | denotes | other |
T10024 | 18837-18838 | . | denotes | . |
T10025 | 18838-18934 | sentence | denotes | Pulmonary hypoplasia was assessed using lung/body weight ratio and radial alveolar counts [26]. |
T10026 | 18839-18848 | JJ | denotes | Pulmonary |
T10027 | 18849-18859 | NN | denotes | hypoplasia |
T10028 | 18864-18872 | VBN | denotes | assessed |
T10029 | 18860-18863 | VBD | denotes | was |
T10030 | 18873-18878 | VBG | denotes | using |
T10031 | 18879-18883 | NN | denotes | lung |
T10032 | 18884-18888 | NN | denotes | body |
T10033 | 18883-18884 | HYPH | denotes | / |
T10034 | 18896-18901 | NN | denotes | ratio |
T10035 | 18889-18895 | NN | denotes | weight |
T10036 | 18902-18905 | CC | denotes | and |
T10037 | 18906-18912 | JJ | denotes | radial |
T10038 | 18922-18928 | NNS | denotes | counts |
T10039 | 18913-18921 | JJ | denotes | alveolar |
T10040 | 18929-18930 | -LRB- | denotes | [ |
T10041 | 18930-18932 | CD | denotes | 26 |
T10042 | 18932-18933 | -RRB- | denotes | ] |
T10043 | 18933-18934 | . | denotes | . |
T10044 | 18934-19072 | sentence | denotes | The material available for review included written reports and histologic slides in all cases and gross kodachromes in a subset of cases. |
T10045 | 18935-18938 | DT | denotes | The |
T10046 | 18939-18947 | NN | denotes | material |
T10047 | 18969-18977 | VBN | denotes | included |
T10048 | 18948-18957 | JJ | denotes | available |
T10049 | 18958-18961 | IN | denotes | for |
T10050 | 18962-18968 | NN | denotes | review |
T10051 | 18978-18985 | VBN | denotes | written |
T10052 | 18986-18993 | NNS | denotes | reports |
T10053 | 18994-18997 | CC | denotes | and |
T10054 | 18998-19008 | JJ | denotes | histologic |
T10055 | 19009-19015 | NNS | denotes | slides |
T10056 | 19016-19018 | IN | denotes | in |
T10057 | 19019-19022 | DT | denotes | all |
T10058 | 19023-19028 | NNS | denotes | cases |
T10059 | 19029-19032 | CC | denotes | and |
T10060 | 19033-19038 | JJ | denotes | gross |
T10061 | 19039-19050 | NNS | denotes | kodachromes |
T10062 | 19051-19053 | IN | denotes | in |
T10063 | 19054-19055 | DT | denotes | a |
T10064 | 19056-19062 | NN | denotes | subset |
T10065 | 19063-19065 | IN | denotes | of |
T10066 | 19066-19071 | NNS | denotes | cases |
T10067 | 19071-19072 | . | denotes | . |
T10068 | 19072-19133 | sentence | denotes | One child carried a highly significant FOG2 sequence change. |
T10069 | 19073-19076 | CD | denotes | One |
T10070 | 19077-19082 | NN | denotes | child |
T10071 | 19083-19090 | VBD | denotes | carried |
T10072 | 19091-19092 | DT | denotes | a |
T10073 | 19126-19132 | NN | denotes | change |
T10074 | 19093-19099 | RB | denotes | highly |
T10075 | 19100-19111 | JJ | denotes | significant |
T10076 | 19112-19116 | NN | denotes | FOG2 |
T10077 | 19117-19125 | NN | denotes | sequence |
T10078 | 19132-19133 | . | denotes | . |
T10079 | 19133-19266 | sentence | denotes | The patient was a full-term 3,500-g baby girl who developed severe respiratory failure at birth and died after 5 h of resuscitation. |
T10080 | 19134-19137 | DT | denotes | The |
T10081 | 19138-19145 | NN | denotes | patient |
T10082 | 19146-19149 | VBD | denotes | was |
T10083 | 19150-19151 | DT | denotes | a |
T10084 | 19175-19179 | NN | denotes | girl |
T10085 | 19152-19156 | JJ | denotes | full |
T10086 | 19157-19161 | NN | denotes | term |
T10087 | 19156-19157 | HYPH | denotes | - |
T10088 | 19162-19167 | CD | denotes | 3,500 |
T10089 | 19168-19169 | NN | denotes | g |
T10090 | 19167-19168 | HYPH | denotes | - |
T10091 | 19170-19174 | NN | denotes | baby |
T10092 | 19180-19183 | WP | denotes | who |
T10093 | 19184-19193 | VBD | denotes | developed |
T10094 | 19194-19200 | JJ | denotes | severe |
T10095 | 19213-19220 | NN | denotes | failure |
T10096 | 19201-19212 | JJ | denotes | respiratory |
T10097 | 19221-19223 | IN | denotes | at |
T10098 | 19224-19229 | NN | denotes | birth |
T10099 | 19230-19233 | CC | denotes | and |
T10100 | 19234-19238 | VBD | denotes | died |
T10101 | 19239-19244 | IN | denotes | after |
T10102 | 19245-19246 | CD | denotes | 5 |
T10103 | 19247-19248 | NN | denotes | h |
T10104 | 19249-19251 | IN | denotes | of |
T10105 | 19252-19265 | NN | denotes | resuscitation |
T10106 | 19265-19266 | . | denotes | . |
T10107 | 19266-19351 | sentence | denotes | Antemortem radiographs showed opacified lung fields and possible bowel in the chest. |
T10108 | 19267-19277 | NN | denotes | Antemortem |
T10109 | 19278-19289 | NNS | denotes | radiographs |
T10110 | 19290-19296 | VBD | denotes | showed |
T10111 | 19297-19306 | VBN | denotes | opacified |
T10112 | 19312-19318 | NNS | denotes | fields |
T10113 | 19307-19311 | NN | denotes | lung |
T10114 | 19319-19322 | CC | denotes | and |
T10115 | 19323-19331 | JJ | denotes | possible |
T10116 | 19332-19337 | NN | denotes | bowel |
T10117 | 19338-19340 | IN | denotes | in |
T10118 | 19341-19344 | DT | denotes | the |
T10119 | 19345-19350 | NN | denotes | chest |
T10120 | 19350-19351 | . | denotes | . |
T10121 | 19351-19393 | sentence | denotes | The patient's clinical diagnosis was CDH. |
T10122 | 19352-19355 | DT | denotes | The |
T10123 | 19356-19363 | NN | denotes | patient |
T10124 | 19375-19384 | NN | denotes | diagnosis |
T10125 | 19363-19365 | POS | denotes | 's |
T10126 | 19366-19374 | JJ | denotes | clinical |
T10127 | 19385-19388 | VBD | denotes | was |
T10128 | 19389-19392 | NN | denotes | CDH |
T10129 | 19392-19393 | . | denotes | . |
T10130 | 19393-19592 | sentence | denotes | Review of autopsy material revealed severe bilateral pulmonary hypoplasia (combined lung weight, 11.1 g; expected for body length/weight, 46.8 ± 26.2 g; [27]), most markedly involving the left lung. |
T10131 | 19394-19400 | NN | denotes | Review |
T10132 | 19421-19429 | VBD | denotes | revealed |
T10133 | 19401-19403 | IN | denotes | of |
T10134 | 19404-19411 | NN | denotes | autopsy |
T10135 | 19412-19420 | NN | denotes | material |
T10136 | 19430-19436 | JJ | denotes | severe |
T10137 | 19457-19467 | NN | denotes | hypoplasia |
T10138 | 19437-19446 | JJ | denotes | bilateral |
T10139 | 19447-19456 | JJ | denotes | pulmonary |
T10140 | 19468-19469 | -LRB- | denotes | ( |
T10141 | 19548-19550 | CD | denotes | 27 |
T10142 | 19469-19477 | VBN | denotes | combined |
T10143 | 19483-19489 | NN | denotes | weight |
T10144 | 19478-19482 | NN | denotes | lung |
T10145 | 19496-19497 | NN | denotes | g |
T10146 | 19489-19491 | , | denotes | , |
T10147 | 19491-19495 | CD | denotes | 11.1 |
T10148 | 19497-19498 | : | denotes | ; |
T10149 | 19499-19507 | VBN | denotes | expected |
T10150 | 19508-19511 | IN | denotes | for |
T10151 | 19512-19516 | NN | denotes | body |
T10152 | 19524-19530 | NN | denotes | weight |
T10153 | 19517-19523 | NN | denotes | length |
T10154 | 19523-19524 | HYPH | denotes | / |
T10155 | 19530-19532 | , | denotes | , |
T10156 | 19532-19536 | CD | denotes | 46.8 |
T10157 | 19539-19543 | CD | denotes | 26.2 |
T10158 | 19537-19538 | SYM | denotes | ± |
T10159 | 19544-19545 | NN | denotes | g |
T10160 | 19545-19546 | : | denotes | ; |
T10161 | 19547-19548 | -LRB- | denotes | [ |
T10162 | 19550-19551 | -RRB- | denotes | ] |
T10163 | 19551-19552 | -RRB- | denotes | ) |
T10164 | 19552-19554 | , | denotes | , |
T10165 | 19554-19558 | RBS | denotes | most |
T10166 | 19559-19567 | RB | denotes | markedly |
T10167 | 19568-19577 | VBG | denotes | involving |
T10168 | 19578-19581 | DT | denotes | the |
T10169 | 19587-19591 | NN | denotes | lung |
T10170 | 19582-19586 | JJ | denotes | left |
T10171 | 19591-19592 | . | denotes | . |
T10172 | 19592-19655 | sentence | denotes | The lung/body weight ratio was 0.0037 (expected > 0.010) [28]. |
T10173 | 19593-19596 | DT | denotes | The |
T10174 | 19614-19619 | NN | denotes | ratio |
T10175 | 19597-19601 | NN | denotes | lung |
T10176 | 19601-19602 | SYM | denotes | / |
T10177 | 19602-19606 | NN | denotes | body |
T10178 | 19607-19613 | NN | denotes | weight |
T10179 | 19620-19623 | VBD | denotes | was |
T10180 | 19624-19630 | CD | denotes | 0.0037 |
T10181 | 19631-19632 | -LRB- | denotes | ( |
T10182 | 19643-19648 | CD | denotes | 0.010 |
T10183 | 19632-19640 | VBN | denotes | expected |
T10184 | 19641-19642 | SYM | denotes | > |
T10185 | 19648-19649 | -RRB- | denotes | ) |
T10186 | 19650-19651 | -LRB- | denotes | [ |
T10187 | 19651-19653 | CD | denotes | 28 |
T10188 | 19653-19654 | -RRB- | denotes | ] |
T10189 | 19654-19655 | . | denotes | . |
T10190 | 19655-19768 | sentence | denotes | There were a reduced number of bronchial generations, and the radial alveolar count was 2–3 (expected = 5) [29]. |
T10191 | 19656-19661 | EX | denotes | There |
T10192 | 19662-19666 | VBD | denotes | were |
T10193 | 19667-19668 | DT | denotes | a |
T10194 | 19677-19683 | NN | denotes | number |
T10195 | 19669-19676 | VBN | denotes | reduced |
T10196 | 19684-19686 | IN | denotes | of |
T10197 | 19687-19696 | JJ | denotes | bronchial |
T10198 | 19697-19708 | NNS | denotes | generations |
T10199 | 19708-19710 | , | denotes | , |
T10200 | 19710-19713 | CC | denotes | and |
T10201 | 19714-19717 | DT | denotes | the |
T10202 | 19734-19739 | NN | denotes | count |
T10203 | 19718-19724 | JJ | denotes | radial |
T10204 | 19725-19733 | JJ | denotes | alveolar |
T10205 | 19740-19743 | VBD | denotes | was |
T10206 | 19744-19745 | CD | denotes | 2 |
T10207 | 19746-19747 | CD | denotes | 3 |
T10208 | 19745-19746 | SYM | denotes | – |
T10209 | 19748-19749 | -LRB- | denotes | ( |
T10210 | 19760-19761 | CD | denotes | 5 |
T10211 | 19749-19757 | VBN | denotes | expected |
T10212 | 19758-19759 | SYM | denotes | = |
T10213 | 19761-19762 | -RRB- | denotes | ) |
T10214 | 19763-19764 | -LRB- | denotes | [ |
T10215 | 19764-19766 | CD | denotes | 29 |
T10216 | 19766-19767 | -RRB- | denotes | ] |
T10217 | 19767-19768 | . | denotes | . |
T10218 | 19768-19817 | sentence | denotes | There were incomplete lung fissures bilaterally. |
T10219 | 19769-19774 | EX | denotes | There |
T10220 | 19775-19779 | VBD | denotes | were |
T10221 | 19780-19790 | JJ | denotes | incomplete |
T10222 | 19796-19804 | NNS | denotes | fissures |
T10223 | 19791-19795 | NN | denotes | lung |
T10224 | 19805-19816 | RB | denotes | bilaterally |
T10225 | 19816-19817 | . | denotes | . |
T10226 | 19817-19890 | sentence | denotes | A deep posterior diaphragmatic eventration was present on the left side. |
T10227 | 19818-19819 | DT | denotes | A |
T10228 | 19849-19860 | NN | denotes | eventration |
T10229 | 19820-19824 | JJ | denotes | deep |
T10230 | 19825-19834 | JJ | denotes | posterior |
T10231 | 19835-19848 | JJ | denotes | diaphragmatic |
T10232 | 19861-19864 | VBD | denotes | was |
T10233 | 19865-19872 | JJ | denotes | present |
T10234 | 19873-19875 | IN | denotes | on |
T10235 | 19876-19879 | DT | denotes | the |
T10236 | 19885-19889 | NN | denotes | side |
T10237 | 19880-19884 | JJ | denotes | left |
T10238 | 19889-19890 | . | denotes | . |
T10239 | 19890-20056 | sentence | denotes | Additionally, two muscularized ligamentous bands resembling diaphragmatic remnants encircled the left lobe of the liver, creating an abnormal fissured liver contour. |
T10240 | 19891-19903 | RB | denotes | Additionally |
T10241 | 19974-19983 | VBD | denotes | encircled |
T10242 | 19903-19905 | , | denotes | , |
T10243 | 19905-19908 | CD | denotes | two |
T10244 | 19934-19939 | NNS | denotes | bands |
T10245 | 19909-19921 | VBN | denotes | muscularized |
T10246 | 19922-19933 | JJ | denotes | ligamentous |
T10247 | 19940-19950 | VBG | denotes | resembling |
T10248 | 19951-19964 | JJ | denotes | diaphragmatic |
T10249 | 19965-19973 | NNS | denotes | remnants |
T10250 | 19984-19987 | DT | denotes | the |
T10251 | 19993-19997 | NN | denotes | lobe |
T10252 | 19988-19992 | JJ | denotes | left |
T10253 | 19998-20000 | IN | denotes | of |
T10254 | 20001-20004 | DT | denotes | the |
T10255 | 20005-20010 | NN | denotes | liver |
T10256 | 20010-20012 | , | denotes | , |
T10257 | 20012-20020 | VBG | denotes | creating |
T10258 | 20021-20023 | DT | denotes | an |
T10259 | 20048-20055 | NN | denotes | contour |
T10260 | 20024-20032 | JJ | denotes | abnormal |
T10261 | 20033-20041 | VBN | denotes | fissured |
T10262 | 20042-20047 | NN | denotes | liver |
T10263 | 20055-20056 | . | denotes | . |
T10264 | 20056-20156 | sentence | denotes | Away from the eventration, the diaphragm appeared well muscularized, measuring 0.3 cm in thickness. |
T10265 | 20057-20061 | RB | denotes | Away |
T10266 | 20098-20106 | VBD | denotes | appeared |
T10267 | 20062-20066 | IN | denotes | from |
T10268 | 20067-20070 | DT | denotes | the |
T10269 | 20071-20082 | NN | denotes | eventration |
T10270 | 20082-20084 | , | denotes | , |
T10271 | 20084-20087 | DT | denotes | the |
T10272 | 20088-20097 | NN | denotes | diaphragm |
T10273 | 20107-20111 | RB | denotes | well |
T10274 | 20112-20124 | VBN | denotes | muscularized |
T10275 | 20124-20126 | , | denotes | , |
T10276 | 20126-20135 | VBG | denotes | measuring |
T10277 | 20136-20139 | CD | denotes | 0.3 |
T10278 | 20140-20142 | NN | denotes | cm |
T10279 | 20143-20145 | IN | denotes | in |
T10280 | 20146-20155 | NN | denotes | thickness |
T10281 | 20155-20156 | . | denotes | . |
T10282 | 20156-20289 | sentence | denotes | A complete autopsy revealed no other malformations; the heart was determined to be grossly normal and was donated for valve harvest. |
T10283 | 20157-20158 | DT | denotes | A |
T10284 | 20168-20175 | NN | denotes | autopsy |
T10285 | 20159-20167 | JJ | denotes | complete |
T10286 | 20176-20184 | VBD | denotes | revealed |
T10287 | 20223-20233 | VBN | denotes | determined |
T10288 | 20185-20187 | DT | denotes | no |
T10289 | 20194-20207 | NNS | denotes | malformations |
T10290 | 20188-20193 | JJ | denotes | other |
T10291 | 20207-20208 | : | denotes | ; |
T10292 | 20209-20212 | DT | denotes | the |
T10293 | 20213-20218 | NN | denotes | heart |
T10294 | 20219-20222 | VBD | denotes | was |
T10295 | 20234-20236 | TO | denotes | to |
T10296 | 20237-20239 | VB | denotes | be |
T10297 | 20240-20247 | RB | denotes | grossly |
T10298 | 20248-20254 | JJ | denotes | normal |
T10299 | 20255-20258 | CC | denotes | and |
T10300 | 20259-20262 | VBD | denotes | was |
T10301 | 20263-20270 | VBN | denotes | donated |
T10302 | 20271-20274 | IN | denotes | for |
T10303 | 20275-20280 | NN | denotes | valve |
T10304 | 20281-20288 | NN | denotes | harvest |
T10305 | 20288-20289 | . | denotes | . |
T10306 | 20289-20433 | sentence | denotes | Sequence analysis revealed a cytosine to thymine heterozygous change in exon 4 that changes the 112th amino acid from arginine to a stop codon. |
T10307 | 20290-20298 | NN | denotes | Sequence |
T10308 | 20299-20307 | NN | denotes | analysis |
T10309 | 20308-20316 | VBD | denotes | revealed |
T10310 | 20317-20318 | DT | denotes | a |
T10311 | 20352-20358 | NN | denotes | change |
T10312 | 20319-20327 | NN | denotes | cytosine |
T10313 | 20328-20330 | IN | denotes | to |
T10314 | 20331-20338 | NN | denotes | thymine |
T10315 | 20339-20351 | JJ | denotes | heterozygous |
T10316 | 20359-20361 | IN | denotes | in |
T10317 | 20362-20366 | NN | denotes | exon |
T10318 | 20367-20368 | CD | denotes | 4 |
T10319 | 20369-20373 | WDT | denotes | that |
T10320 | 20374-20381 | VBZ | denotes | changes |
T10321 | 20382-20385 | DT | denotes | the |
T10322 | 20398-20402 | NN | denotes | acid |
T10323 | 20386-20391 | JJ | denotes | 112th |
T10324 | 20392-20397 | NN | denotes | amino |
T10325 | 20403-20407 | IN | denotes | from |
T10326 | 20408-20416 | NN | denotes | arginine |
T10327 | 20417-20419 | IN | denotes | to |
T10328 | 20420-20421 | DT | denotes | a |
T10329 | 20427-20432 | NN | denotes | codon |
T10330 | 20422-20426 | NN | denotes | stop |
T10331 | 20432-20433 | . | denotes | . |
T10332 | 20433-20539 | sentence | denotes | This mutation produces a severely truncated peptide that does not contain zinc finger domains (Figure 7). |
T10333 | 20434-20438 | DT | denotes | This |
T10334 | 20439-20447 | NN | denotes | mutation |
T10335 | 20448-20456 | VBZ | denotes | produces |
T10336 | 20457-20458 | DT | denotes | a |
T10337 | 20478-20485 | NN | denotes | peptide |
T10338 | 20459-20467 | RB | denotes | severely |
T10339 | 20468-20477 | VBN | denotes | truncated |
T10340 | 20486-20490 | WDT | denotes | that |
T10341 | 20500-20507 | VB | denotes | contain |
T10342 | 20491-20495 | VBZ | denotes | does |
T10343 | 20496-20499 | RB | denotes | not |
T10344 | 20508-20512 | NN | denotes | zinc |
T10345 | 20513-20519 | NN | denotes | finger |
T10346 | 20520-20527 | NNS | denotes | domains |
T10347 | 20528-20529 | -LRB- | denotes | ( |
T10348 | 20529-20535 | NN | denotes | Figure |
T10349 | 20536-20537 | CD | denotes | 7 |
T10350 | 20537-20538 | -RRB- | denotes | ) |
T10351 | 20538-20539 | . | denotes | . |
T10352 | 20539-20619 | sentence | denotes | This base change was not present in the analysis of DNA from 400 normal adults. |
T10353 | 20540-20544 | DT | denotes | This |
T10354 | 20550-20556 | NN | denotes | change |
T10355 | 20545-20549 | NN | denotes | base |
T10356 | 20557-20560 | VBD | denotes | was |
T10357 | 20561-20564 | RB | denotes | not |
T10358 | 20565-20572 | JJ | denotes | present |
T10359 | 20573-20575 | IN | denotes | in |
T10360 | 20576-20579 | DT | denotes | the |
T10361 | 20580-20588 | NN | denotes | analysis |
T10362 | 20589-20591 | IN | denotes | of |
T10363 | 20592-20595 | NN | denotes | DNA |
T10364 | 20596-20600 | IN | denotes | from |
T10365 | 20601-20604 | CD | denotes | 400 |
T10366 | 20612-20618 | NNS | denotes | adults |
T10367 | 20605-20611 | JJ | denotes | normal |
T10368 | 20618-20619 | . | denotes | . |
T10369 | 20619-20732 | sentence | denotes | To assess the likelihood that the mutation was causal for the developmental phenotype, we examined both parents. |
T10370 | 20620-20622 | TO | denotes | To |
T10371 | 20623-20629 | VB | denotes | assess |
T10372 | 20710-20718 | VBD | denotes | examined |
T10373 | 20630-20633 | DT | denotes | the |
T10374 | 20634-20644 | NN | denotes | likelihood |
T10375 | 20645-20649 | IN | denotes | that |
T10376 | 20663-20666 | VBD | denotes | was |
T10377 | 20650-20653 | DT | denotes | the |
T10378 | 20654-20662 | NN | denotes | mutation |
T10379 | 20667-20673 | JJ | denotes | causal |
T10380 | 20674-20677 | IN | denotes | for |
T10381 | 20678-20681 | DT | denotes | the |
T10382 | 20696-20705 | NN | denotes | phenotype |
T10383 | 20682-20695 | JJ | denotes | developmental |
T10384 | 20705-20707 | , | denotes | , |
T10385 | 20707-20709 | PRP | denotes | we |
T10386 | 20719-20723 | DT | denotes | both |
T10387 | 20724-20731 | NNS | denotes | parents |
T10388 | 20731-20732 | . | denotes | . |
T10389 | 20732-20903 | sentence | denotes | Paternity was confirmed, and sequence analysis revealed that the neither parent carried this mutation, proving that the patient had a de novo mutation in FOG2 (Figure 7). |
T10390 | 20733-20742 | NN | denotes | Paternity |
T10391 | 20747-20756 | VBN | denotes | confirmed |
T10392 | 20743-20746 | VBD | denotes | was |
T10393 | 20756-20758 | , | denotes | , |
T10394 | 20758-20761 | CC | denotes | and |
T10395 | 20762-20770 | NN | denotes | sequence |
T10396 | 20771-20779 | NN | denotes | analysis |
T10397 | 20780-20788 | VBD | denotes | revealed |
T10398 | 20789-20793 | IN | denotes | that |
T10399 | 20813-20820 | VBD | denotes | carried |
T10400 | 20794-20797 | DT | denotes | the |
T10401 | 20806-20812 | NN | denotes | parent |
T10402 | 20798-20805 | CC | denotes | neither |
T10403 | 20821-20825 | DT | denotes | this |
T10404 | 20826-20834 | NN | denotes | mutation |
T10405 | 20834-20836 | , | denotes | , |
T10406 | 20836-20843 | VBG | denotes | proving |
T10407 | 20844-20848 | IN | denotes | that |
T10408 | 20861-20864 | VBD | denotes | had |
T10409 | 20849-20852 | DT | denotes | the |
T10410 | 20853-20860 | NN | denotes | patient |
T10411 | 20865-20866 | DT | denotes | a |
T10412 | 20875-20883 | NN | denotes | mutation |
T10413 | 20867-20869 | FW | denotes | de |
T10414 | 20870-20874 | FW | denotes | novo |
T10415 | 20884-20886 | IN | denotes | in |
T10416 | 20887-20891 | NN | denotes | FOG2 |
T10417 | 20892-20893 | -LRB- | denotes | ( |
T10418 | 20893-20899 | NN | denotes | Figure |
T10419 | 20900-20901 | CD | denotes | 7 |
T10420 | 20901-20902 | -RRB- | denotes | ) |
T10421 | 20902-20903 | . | denotes | . |
T13037 | 21278-21288 | JJ | denotes | Congenital |
T13038 | 21303-21310 | NNS | denotes | defects |
T13039 | 21289-21302 | JJ | denotes | diaphragmatic |
T13040 | 21311-21314 | VBP | denotes | are |
T13041 | 21315-21316 | DT | denotes | a |
T13042 | 21331-21336 | NN | denotes | group |
T13043 | 21317-21330 | JJ | denotes | heterogeneous |
T13044 | 21337-21339 | IN | denotes | of |
T13045 | 21340-21349 | NNS | denotes | disorders |
T13046 | 21350-21352 | IN | denotes | of |
T13047 | 21353-21360 | JJ | denotes | unknown |
T13048 | 21361-21369 | NN | denotes | etiology |
T13049 | 21369-21370 | . | denotes | . |
T13050 | 21370-21540 | sentence | denotes | The defects that present in the pre- or perinatal period include Bochdalek hernia, diaphragmatic aplasia, and various degrees of muscularization defects or eventrations. |
T13051 | 21371-21374 | DT | denotes | The |
T13052 | 21375-21382 | NNS | denotes | defects |
T13053 | 21428-21435 | VBP | denotes | include |
T13054 | 21383-21387 | WDT | denotes | that |
T13055 | 21388-21395 | VBP | denotes | present |
T13056 | 21396-21398 | IN | denotes | in |
T13057 | 21399-21402 | DT | denotes | the |
T13058 | 21421-21427 | NN | denotes | period |
T13059 | 21403-21406 | AFX | denotes | pre |
T13060 | 21411-21420 | JJ | denotes | perinatal |
T13061 | 21406-21407 | HYPH | denotes | - |
T13062 | 21408-21410 | CC | denotes | or |
T13063 | 21436-21445 | NNP | denotes | Bochdalek |
T13064 | 21446-21452 | NN | denotes | hernia |
T13065 | 21452-21454 | , | denotes | , |
T13066 | 21454-21467 | JJ | denotes | diaphragmatic |
T13067 | 21468-21475 | NN | denotes | aplasia |
T13068 | 21475-21477 | , | denotes | , |
T13069 | 21477-21480 | CC | denotes | and |
T13070 | 21481-21488 | JJ | denotes | various |
T13071 | 21489-21496 | NNS | denotes | degrees |
T13072 | 21497-21499 | IN | denotes | of |
T13073 | 21500-21515 | NN | denotes | muscularization |
T13074 | 21516-21523 | NNS | denotes | defects |
T13075 | 21524-21526 | CC | denotes | or |
T13076 | 21527-21539 | NNS | denotes | eventrations |
T13077 | 21539-21540 | . | denotes | . |
T13078 | 21540-21702 | sentence | denotes | Different types of defects occur in the same patients or in siblings, suggesting these represent variable expression of the same underlying pathogenesis [30,31]. |
T13079 | 21541-21550 | JJ | denotes | Different |
T13080 | 21551-21556 | NNS | denotes | types |
T13081 | 21568-21573 | VBP | denotes | occur |
T13082 | 21557-21559 | IN | denotes | of |
T13083 | 21560-21567 | NNS | denotes | defects |
T13084 | 21574-21576 | IN | denotes | in |
T13085 | 21577-21580 | DT | denotes | the |
T13086 | 21586-21594 | NNS | denotes | patients |
T13087 | 21581-21585 | JJ | denotes | same |
T13088 | 21595-21597 | CC | denotes | or |
T13089 | 21598-21600 | IN | denotes | in |
T13090 | 21601-21609 | NNS | denotes | siblings |
T13091 | 21609-21611 | , | denotes | , |
T13092 | 21611-21621 | VBG | denotes | suggesting |
T13093 | 21622-21627 | DT | denotes | these |
T13094 | 21628-21637 | VBP | denotes | represent |
T13095 | 21638-21646 | JJ | denotes | variable |
T13096 | 21647-21657 | NN | denotes | expression |
T13097 | 21658-21660 | IN | denotes | of |
T13098 | 21661-21664 | DT | denotes | the |
T13099 | 21681-21693 | NN | denotes | pathogenesis |
T13100 | 21665-21669 | JJ | denotes | same |
T13101 | 21670-21680 | VBG | denotes | underlying |
T13102 | 21694-21695 | -LRB- | denotes | [ |
T13103 | 21698-21700 | CD | denotes | 31 |
T13104 | 21695-21697 | CD | denotes | 30 |
T13105 | 21697-21698 | , | denotes | , |
T13106 | 21700-21701 | -RRB- | denotes | ] |
T13107 | 21701-21702 | . | denotes | . |
T13108 | 21702-21935 | sentence | denotes | Clinical differentiation between these defects may be very difficult, as the residual membranous diaphragm of a muscularization defect is thin and may not be easily visible on prenatal ultrasound or postnatal chest radiographs [32]. |
T13109 | 21703-21711 | JJ | denotes | Clinical |
T13110 | 21712-21727 | NN | denotes | differentiation |
T13111 | 21754-21756 | VB | denotes | be |
T13112 | 21728-21735 | IN | denotes | between |
T13113 | 21736-21741 | DT | denotes | these |
T13114 | 21742-21749 | NNS | denotes | defects |
T13115 | 21750-21753 | MD | denotes | may |
T13116 | 21757-21761 | RB | denotes | very |
T13117 | 21762-21771 | JJ | denotes | difficult |
T13118 | 21771-21773 | , | denotes | , |
T13119 | 21773-21775 | IN | denotes | as |
T13120 | 21838-21840 | VBZ | denotes | is |
T13121 | 21776-21779 | DT | denotes | the |
T13122 | 21800-21809 | NN | denotes | diaphragm |
T13123 | 21780-21788 | JJ | denotes | residual |
T13124 | 21789-21799 | JJ | denotes | membranous |
T13125 | 21810-21812 | IN | denotes | of |
T13126 | 21813-21814 | DT | denotes | a |
T13127 | 21831-21837 | NN | denotes | defect |
T13128 | 21815-21830 | NN | denotes | muscularization |
T13129 | 21841-21845 | JJ | denotes | thin |
T13130 | 21846-21849 | CC | denotes | and |
T13131 | 21850-21853 | MD | denotes | may |
T13132 | 21858-21860 | VB | denotes | be |
T13133 | 21854-21857 | RB | denotes | not |
T13134 | 21861-21867 | RB | denotes | easily |
T13135 | 21868-21875 | JJ | denotes | visible |
T13136 | 21876-21878 | IN | denotes | on |
T13137 | 21879-21887 | JJ | denotes | prenatal |
T13138 | 21888-21898 | JJ | denotes | ultrasound |
T13139 | 21899-21901 | CC | denotes | or |
T13140 | 21902-21911 | JJ | denotes | postnatal |
T13141 | 21918-21929 | NNS | denotes | radiographs |
T13142 | 21912-21917 | NN | denotes | chest |
T13143 | 21930-21931 | -LRB- | denotes | [ |
T13144 | 21931-21933 | CD | denotes | 32 |
T13145 | 21933-21934 | -RRB- | denotes | ] |
T13146 | 21934-21935 | . | denotes | . |
T13147 | 21935-22194 | sentence | denotes | Although diaphragmatic muscularization defects were historically considered to be predictive of a good outcome, there have been inadequate population-based studies that include fetal or neonatal cases and autopsy diagnoses to make this conclusion definitive. |
T13148 | 21936-21944 | IN | denotes | Although |
T13149 | 22001-22011 | VBN | denotes | considered |
T13150 | 21945-21958 | JJ | denotes | diaphragmatic |
T13151 | 21975-21982 | NNS | denotes | defects |
T13152 | 21959-21974 | NN | denotes | muscularization |
T13153 | 21983-21987 | VBD | denotes | were |
T13154 | 21988-22000 | RB | denotes | historically |
T13155 | 22059-22063 | VBN | denotes | been |
T13156 | 22012-22014 | TO | denotes | to |
T13157 | 22015-22017 | VB | denotes | be |
T13158 | 22018-22028 | JJ | denotes | predictive |
T13159 | 22029-22031 | IN | denotes | of |
T13160 | 22032-22033 | DT | denotes | a |
T13161 | 22039-22046 | NN | denotes | outcome |
T13162 | 22034-22038 | JJ | denotes | good |
T13163 | 22046-22048 | , | denotes | , |
T13164 | 22048-22053 | EX | denotes | there |
T13165 | 22054-22058 | VBP | denotes | have |
T13166 | 22064-22074 | JJ | denotes | inadequate |
T13167 | 22092-22099 | NNS | denotes | studies |
T13168 | 22075-22085 | NN | denotes | population |
T13169 | 22086-22091 | VBN | denotes | based |
T13170 | 22085-22086 | HYPH | denotes | - |
T13171 | 22100-22104 | WDT | denotes | that |
T13172 | 22105-22112 | VBP | denotes | include |
T13173 | 22113-22118 | JJ | denotes | fetal |
T13174 | 22131-22136 | NNS | denotes | cases |
T13175 | 22119-22121 | CC | denotes | or |
T13176 | 22122-22130 | JJ | denotes | neonatal |
T13177 | 22137-22140 | CC | denotes | and |
T13178 | 22141-22148 | NN | denotes | autopsy |
T13179 | 22149-22158 | NNS | denotes | diagnoses |
T13180 | 22159-22161 | TO | denotes | to |
T13181 | 22162-22166 | VB | denotes | make |
T13182 | 22167-22171 | DT | denotes | this |
T13183 | 22172-22182 | NN | denotes | conclusion |
T13184 | 22183-22193 | JJ | denotes | definitive |
T13185 | 22193-22194 | . | denotes | . |
T13186 | 22194-22445 | sentence | denotes | In fact, the series of patients we report here and the published literature indicate that an eventration defect may be associated with displacement of abdominal contents and also with severe pulmonary hypoplasia and respiratory insufficiency [33,34]. |
T13187 | 22195-22197 | IN | denotes | In |
T13188 | 22271-22279 | VBP | denotes | indicate |
T13189 | 22198-22202 | NN | denotes | fact |
T13190 | 22202-22204 | , | denotes | , |
T13191 | 22204-22207 | DT | denotes | the |
T13192 | 22208-22214 | NN | denotes | series |
T13193 | 22215-22217 | IN | denotes | of |
T13194 | 22218-22226 | NNS | denotes | patients |
T13195 | 22227-22229 | PRP | denotes | we |
T13196 | 22230-22236 | VBP | denotes | report |
T13197 | 22237-22241 | RB | denotes | here |
T13198 | 22242-22245 | CC | denotes | and |
T13199 | 22246-22249 | DT | denotes | the |
T13200 | 22260-22270 | NN | denotes | literature |
T13201 | 22250-22259 | VBN | denotes | published |
T13202 | 22280-22284 | IN | denotes | that |
T13203 | 22314-22324 | VBN | denotes | associated |
T13204 | 22285-22287 | DT | denotes | an |
T13205 | 22300-22306 | NN | denotes | defect |
T13206 | 22288-22299 | NN | denotes | eventration |
T13207 | 22307-22310 | MD | denotes | may |
T13208 | 22311-22313 | VB | denotes | be |
T13209 | 22325-22329 | IN | denotes | with |
T13210 | 22330-22342 | NN | denotes | displacement |
T13211 | 22343-22345 | IN | denotes | of |
T13212 | 22346-22355 | JJ | denotes | abdominal |
T13213 | 22356-22364 | NNS | denotes | contents |
T13214 | 22365-22368 | CC | denotes | and |
T13215 | 22369-22373 | RB | denotes | also |
T13216 | 22374-22378 | IN | denotes | with |
T13217 | 22379-22385 | JJ | denotes | severe |
T13218 | 22396-22406 | NN | denotes | hypoplasia |
T13219 | 22386-22395 | JJ | denotes | pulmonary |
T13220 | 22407-22410 | CC | denotes | and |
T13221 | 22411-22422 | JJ | denotes | respiratory |
T13222 | 22423-22436 | NN | denotes | insufficiency |
T13223 | 22437-22438 | -LRB- | denotes | [ |
T13224 | 22441-22443 | CD | denotes | 34 |
T13225 | 22438-22440 | CD | denotes | 33 |
T13226 | 22440-22441 | , | denotes | , |
T13227 | 22443-22444 | -RRB- | denotes | ] |
T13228 | 22444-22445 | . | denotes | . |
T13229 | 22445-22559 | sentence | denotes | Numerous chromosome abnormalities have been found in association with congenital diaphragm abnormalities [12,35]. |
T13230 | 22446-22454 | JJ | denotes | Numerous |
T13231 | 22466-22479 | NNS | denotes | abnormalities |
T13232 | 22455-22465 | NN | denotes | chromosome |
T13233 | 22490-22495 | VBN | denotes | found |
T13234 | 22480-22484 | VBP | denotes | have |
T13235 | 22485-22489 | VBN | denotes | been |
T13236 | 22496-22498 | IN | denotes | in |
T13237 | 22499-22510 | NN | denotes | association |
T13238 | 22511-22515 | IN | denotes | with |
T13239 | 22516-22526 | JJ | denotes | congenital |
T13240 | 22537-22550 | NNS | denotes | abnormalities |
T13241 | 22527-22536 | NN | denotes | diaphragm |
T13242 | 22551-22552 | -LRB- | denotes | [ |
T13243 | 22555-22557 | CD | denotes | 35 |
T13244 | 22552-22554 | CD | denotes | 12 |
T13245 | 22554-22555 | , | denotes | , |
T13246 | 22557-22558 | -RRB- | denotes | ] |
T13247 | 22558-22559 | . | denotes | . |
T13248 | 22559-22715 | sentence | denotes | Human FOG2 maps to Chromosome 8q23.1, and, importantly, several patients with diaphragm defects and rearrangements involving this locus have been reported. |
T13249 | 22560-22565 | JJ | denotes | Human |
T13250 | 22566-22570 | NN | denotes | FOG2 |
T13251 | 22571-22575 | VBZ | denotes | maps |
T13252 | 22576-22578 | IN | denotes | to |
T13253 | 22579-22589 | NN | denotes | Chromosome |
T13254 | 22590-22596 | CD | denotes | 8q23.1 |
T13255 | 22596-22598 | , | denotes | , |
T13256 | 22598-22601 | CC | denotes | and |
T13257 | 22601-22603 | , | denotes | , |
T13258 | 22603-22614 | RB | denotes | importantly |
T13259 | 22706-22714 | VBN | denotes | reported |
T13260 | 22614-22616 | , | denotes | , |
T13261 | 22616-22623 | JJ | denotes | several |
T13262 | 22624-22632 | NNS | denotes | patients |
T13263 | 22633-22637 | IN | denotes | with |
T13264 | 22638-22647 | NN | denotes | diaphragm |
T13265 | 22648-22655 | NNS | denotes | defects |
T13266 | 22656-22659 | CC | denotes | and |
T13267 | 22660-22674 | NNS | denotes | rearrangements |
T13268 | 22675-22684 | VBG | denotes | involving |
T13269 | 22685-22689 | DT | denotes | this |
T13270 | 22690-22695 | NN | denotes | locus |
T13271 | 22696-22700 | VBP | denotes | have |
T13272 | 22701-22705 | VBN | denotes | been |
T13273 | 22714-22715 | . | denotes | . |
T13274 | 22715-22848 | sentence | denotes | Specifically, there are three unrelated CDH patients with cytogenetically balanced translocations at or near the FOG2 locus [36,37]. |
T13275 | 22716-22728 | RB | denotes | Specifically |
T13276 | 22736-22739 | VBP | denotes | are |
T13277 | 22728-22730 | , | denotes | , |
T13278 | 22730-22735 | EX | denotes | there |
T13279 | 22740-22745 | CD | denotes | three |
T13280 | 22760-22768 | NNS | denotes | patients |
T13281 | 22746-22755 | JJ | denotes | unrelated |
T13282 | 22756-22759 | NN | denotes | CDH |
T13283 | 22769-22773 | IN | denotes | with |
T13284 | 22774-22789 | RB | denotes | cytogenetically |
T13285 | 22790-22798 | VBN | denotes | balanced |
T13286 | 22799-22813 | NNS | denotes | translocations |
T13287 | 22814-22816 | IN | denotes | at |
T13288 | 22817-22819 | CC | denotes | or |
T13289 | 22820-22824 | IN | denotes | near |
T13290 | 22825-22828 | DT | denotes | the |
T13291 | 22834-22839 | NN | denotes | locus |
T13292 | 22829-22833 | NN | denotes | FOG2 |
T13293 | 22840-22841 | -LRB- | denotes | [ |
T13294 | 22844-22846 | CD | denotes | 37 |
T13295 | 22841-22843 | CD | denotes | 36 |
T13296 | 22843-22844 | , | denotes | , |
T13297 | 22846-22847 | -RRB- | denotes | ] |
T13298 | 22847-22848 | . | denotes | . |
T13299 | 22848-22997 | sentence | denotes | Additionally, two patients with deletions apparently encompassing the FOG2 locus have died from multiple congenital anomalies including CDH [38–40]. |
T13300 | 22849-22861 | RB | denotes | Additionally |
T13301 | 22935-22939 | VBN | denotes | died |
T13302 | 22861-22863 | , | denotes | , |
T13303 | 22863-22866 | CD | denotes | two |
T13304 | 22867-22875 | NNS | denotes | patients |
T13305 | 22876-22880 | IN | denotes | with |
T13306 | 22881-22890 | NNS | denotes | deletions |
T13307 | 22891-22901 | RB | denotes | apparently |
T13308 | 22902-22914 | VBG | denotes | encompassing |
T13309 | 22915-22918 | DT | denotes | the |
T13310 | 22924-22929 | NN | denotes | locus |
T13311 | 22919-22923 | NN | denotes | FOG2 |
T13312 | 22930-22934 | VBP | denotes | have |
T13313 | 22940-22944 | IN | denotes | from |
T13314 | 22945-22953 | JJ | denotes | multiple |
T13315 | 22965-22974 | NNS | denotes | anomalies |
T13316 | 22954-22964 | JJ | denotes | congenital |
T13317 | 22975-22984 | VBG | denotes | including |
T13318 | 22985-22988 | NN | denotes | CDH |
T13319 | 22989-22990 | -LRB- | denotes | [ |
T13320 | 22990-22992 | CD | denotes | 38 |
T13321 | 22992-22993 | SYM | denotes | – |
T13322 | 22993-22995 | CD | denotes | 40 |
T13323 | 22995-22996 | -RRB- | denotes | ] |
T13324 | 22996-22997 | . | denotes | . |
T13325 | 22997-23161 | sentence | denotes | Inactivation of this gene due to chromosomal rearrangement or deletion would result in a heterozygous null mutation similar to that found in the patient we report. |
T13326 | 22998-23010 | NN | denotes | Inactivation |
T13327 | 23075-23081 | VB | denotes | result |
T13328 | 23011-23013 | IN | denotes | of |
T13329 | 23014-23018 | DT | denotes | this |
T13330 | 23019-23023 | NN | denotes | gene |
T13331 | 23024-23027 | IN | denotes | due |
T13332 | 23028-23030 | IN | denotes | to |
T13333 | 23031-23042 | JJ | denotes | chromosomal |
T13334 | 23043-23056 | NN | denotes | rearrangement |
T13335 | 23057-23059 | CC | denotes | or |
T13336 | 23060-23068 | NN | denotes | deletion |
T13337 | 23069-23074 | MD | denotes | would |
T13338 | 23082-23084 | IN | denotes | in |
T13339 | 23085-23086 | DT | denotes | a |
T13340 | 23105-23113 | NN | denotes | mutation |
T13341 | 23087-23099 | JJ | denotes | heterozygous |
T13342 | 23100-23104 | JJ | denotes | null |
T13343 | 23114-23121 | JJ | denotes | similar |
T13344 | 23122-23124 | IN | denotes | to |
T13345 | 23125-23129 | DT | denotes | that |
T13346 | 23130-23135 | VBN | denotes | found |
T13347 | 23136-23138 | IN | denotes | in |
T13348 | 23139-23142 | DT | denotes | the |
T13349 | 23143-23150 | NN | denotes | patient |
T13350 | 23151-23153 | PRP | denotes | we |
T13351 | 23154-23160 | VBP | denotes | report |
T13352 | 23160-23161 | . | denotes | . |
T13353 | 23161-23434 | sentence | denotes | Because the FOG2 mutation we report is de novo and the phenotypes of the pulmonary and diaphragmatic defects are similar between mouse and human, we suggest that this mutation in FOG2 is the first reported cause of a human developmental diaphragmatic and pulmonary defect. |
T13354 | 23162-23169 | IN | denotes | Because |
T13355 | 23198-23200 | VBZ | denotes | is |
T13356 | 23170-23173 | DT | denotes | the |
T13357 | 23179-23187 | NN | denotes | mutation |
T13358 | 23174-23178 | NN | denotes | FOG2 |
T13359 | 23188-23190 | PRP | denotes | we |
T13360 | 23191-23197 | VBP | denotes | report |
T13361 | 23311-23318 | VBP | denotes | suggest |
T13362 | 23201-23203 | FW | denotes | de |
T13363 | 23204-23208 | FW | denotes | novo |
T13364 | 23209-23212 | CC | denotes | and |
T13365 | 23213-23216 | DT | denotes | the |
T13366 | 23217-23227 | NNS | denotes | phenotypes |
T13367 | 23271-23274 | VBP | denotes | are |
T13368 | 23228-23230 | IN | denotes | of |
T13369 | 23231-23234 | DT | denotes | the |
T13370 | 23263-23270 | NNS | denotes | defects |
T13371 | 23235-23244 | JJ | denotes | pulmonary |
T13372 | 23245-23248 | CC | denotes | and |
T13373 | 23249-23262 | JJ | denotes | diaphragmatic |
T13374 | 23275-23282 | JJ | denotes | similar |
T13375 | 23283-23290 | IN | denotes | between |
T13376 | 23291-23296 | NN | denotes | mouse |
T13377 | 23297-23300 | CC | denotes | and |
T13378 | 23301-23306 | JJ | denotes | human |
T13379 | 23306-23308 | , | denotes | , |
T13380 | 23308-23310 | PRP | denotes | we |
T13381 | 23319-23323 | IN | denotes | that |
T13382 | 23346-23348 | VBZ | denotes | is |
T13383 | 23324-23328 | DT | denotes | this |
T13384 | 23329-23337 | NN | denotes | mutation |
T13385 | 23338-23340 | IN | denotes | in |
T13386 | 23341-23345 | NN | denotes | FOG2 |
T13387 | 23349-23352 | DT | denotes | the |
T13388 | 23368-23373 | NN | denotes | cause |
T13389 | 23353-23358 | JJ | denotes | first |
T13390 | 23359-23367 | VBN | denotes | reported |
T13391 | 23374-23376 | IN | denotes | of |
T13392 | 23377-23378 | DT | denotes | a |
T13393 | 23427-23433 | NN | denotes | defect |
T13394 | 23379-23384 | JJ | denotes | human |
T13395 | 23385-23398 | JJ | denotes | developmental |
T13396 | 23399-23412 | JJ | denotes | diaphragmatic |
T13397 | 23413-23416 | CC | denotes | and |
T13398 | 23417-23426 | JJ | denotes | pulmonary |
T13399 | 23433-23434 | . | denotes | . |
T13400 | 23434-23530 | sentence | denotes | In contrast to the affected child, mice heterozygous for a null mutation of Fog2 appear normal. |
T13401 | 23435-23437 | IN | denotes | In |
T13402 | 23516-23522 | VBP | denotes | appear |
T13403 | 23438-23446 | NN | denotes | contrast |
T13404 | 23447-23449 | IN | denotes | to |
T13405 | 23450-23453 | DT | denotes | the |
T13406 | 23463-23468 | NN | denotes | child |
T13407 | 23454-23462 | VBN | denotes | affected |
T13408 | 23468-23470 | , | denotes | , |
T13409 | 23470-23474 | NNS | denotes | mice |
T13410 | 23475-23487 | JJ | denotes | heterozygous |
T13411 | 23488-23491 | IN | denotes | for |
T13412 | 23492-23493 | DT | denotes | a |
T13413 | 23499-23507 | NN | denotes | mutation |
T13414 | 23494-23498 | JJ | denotes | null |
T13415 | 23508-23510 | IN | denotes | of |
T13416 | 23511-23515 | NN | denotes | Fog2 |
T13417 | 23523-23529 | JJ | denotes | normal |
T13418 | 23529-23530 | . | denotes | . |
T13419 | 23530-23701 | sentence | denotes | However, there is ample precedent for the observation that haploinsufficiency of a gene with developmental functions is much less well tolerated in humans than mice [41]. |
T13420 | 23531-23538 | RB | denotes | However |
T13421 | 23546-23548 | VBZ | denotes | is |
T13422 | 23538-23540 | , | denotes | , |
T13423 | 23540-23545 | EX | denotes | there |
T13424 | 23549-23554 | JJ | denotes | ample |
T13425 | 23555-23564 | NN | denotes | precedent |
T13426 | 23565-23568 | IN | denotes | for |
T13427 | 23569-23572 | DT | denotes | the |
T13428 | 23573-23584 | NN | denotes | observation |
T13429 | 23585-23589 | IN | denotes | that |
T13430 | 23648-23650 | VBZ | denotes | is |
T13431 | 23590-23608 | NN | denotes | haploinsufficiency |
T13432 | 23609-23611 | IN | denotes | of |
T13433 | 23612-23613 | DT | denotes | a |
T13434 | 23614-23618 | NN | denotes | gene |
T13435 | 23619-23623 | IN | denotes | with |
T13436 | 23624-23637 | JJ | denotes | developmental |
T13437 | 23638-23647 | NNS | denotes | functions |
T13438 | 23651-23655 | RB | denotes | much |
T13439 | 23656-23660 | RBR | denotes | less |
T13440 | 23661-23665 | RB | denotes | well |
T13441 | 23666-23675 | VBN | denotes | tolerated |
T13442 | 23676-23678 | IN | denotes | in |
T13443 | 23679-23685 | NNS | denotes | humans |
T13444 | 23686-23690 | IN | denotes | than |
T13445 | 23691-23695 | NNS | denotes | mice |
T13446 | 23696-23697 | -LRB- | denotes | [ |
T13447 | 23697-23699 | CD | denotes | 41 |
T13448 | 23699-23700 | -RRB- | denotes | ] |
T13449 | 23700-23701 | . | denotes | . |
T13450 | 23701-23850 | sentence | denotes | It is unclear how the Fog2 diaphragmatic defect relates to the more common Bochdalek CDH, as the pathogenic mechanisms for both are largely unknown. |
T13451 | 23702-23704 | PRP | denotes | It |
T13452 | 23705-23707 | VBZ | denotes | is |
T13453 | 23708-23715 | JJ | denotes | unclear |
T13454 | 23716-23719 | WRB | denotes | how |
T13455 | 23750-23757 | VBZ | denotes | relates |
T13456 | 23720-23723 | DT | denotes | the |
T13457 | 23743-23749 | NN | denotes | defect |
T13458 | 23724-23728 | NN | denotes | Fog2 |
T13459 | 23729-23742 | JJ | denotes | diaphragmatic |
T13460 | 23758-23760 | IN | denotes | to |
T13461 | 23761-23764 | DT | denotes | the |
T13462 | 23787-23790 | NN | denotes | CDH |
T13463 | 23765-23769 | RBR | denotes | more |
T13464 | 23770-23776 | JJ | denotes | common |
T13465 | 23777-23786 | NNP | denotes | Bochdalek |
T13466 | 23790-23792 | , | denotes | , |
T13467 | 23792-23794 | IN | denotes | as |
T13468 | 23830-23833 | VBP | denotes | are |
T13469 | 23795-23798 | DT | denotes | the |
T13470 | 23810-23820 | NNS | denotes | mechanisms |
T13471 | 23799-23809 | JJ | denotes | pathogenic |
T13472 | 23821-23824 | IN | denotes | for |
T13473 | 23825-23829 | DT | denotes | both |
T13474 | 23834-23841 | RB | denotes | largely |
T13475 | 23842-23849 | JJ | denotes | unknown |
T13476 | 23849-23850 | . | denotes | . |
T13477 | 23850-23962 | sentence | denotes | Muscle precursors destined to populate the diaphragm migrate from the lateral dermomyotome of cervical somites. |
T13478 | 23851-23857 | NN | denotes | Muscle |
T13479 | 23858-23868 | NNS | denotes | precursors |
T13480 | 23904-23911 | VBP | denotes | migrate |
T13481 | 23869-23877 | VBN | denotes | destined |
T13482 | 23878-23880 | TO | denotes | to |
T13483 | 23881-23889 | VB | denotes | populate |
T13484 | 23890-23893 | DT | denotes | the |
T13485 | 23894-23903 | NN | denotes | diaphragm |
T13486 | 23912-23916 | IN | denotes | from |
T13487 | 23917-23920 | DT | denotes | the |
T13488 | 23929-23941 | NN | denotes | dermomyotome |
T13489 | 23921-23928 | JJ | denotes | lateral |
T13490 | 23942-23944 | IN | denotes | of |
T13491 | 23945-23953 | JJ | denotes | cervical |
T13492 | 23954-23961 | NNS | denotes | somites |
T13493 | 23961-23962 | . | denotes | . |
T13494 | 23962-24176 | sentence | denotes | Prior to migration onto the diaphragm, they populate the PPF, a wedge-shaped tissue that tapers medially from the lateral body wall to the esophageal mesentery and fuses ventrally with the septum transversum [42]. |
T13495 | 23963-23968 | RB | denotes | Prior |
T13496 | 23969-23971 | IN | denotes | to |
T13497 | 24007-24015 | VBP | denotes | populate |
T13498 | 23972-23981 | NN | denotes | migration |
T13499 | 23982-23986 | IN | denotes | onto |
T13500 | 23987-23990 | DT | denotes | the |
T13501 | 23991-24000 | NN | denotes | diaphragm |
T13502 | 24000-24002 | , | denotes | , |
T13503 | 24002-24006 | PRP | denotes | they |
T13504 | 24016-24019 | DT | denotes | the |
T13505 | 24020-24023 | NN | denotes | PPF |
T13506 | 24023-24025 | , | denotes | , |
T13507 | 24025-24026 | DT | denotes | a |
T13508 | 24040-24046 | NN | denotes | tissue |
T13509 | 24027-24032 | NN | denotes | wedge |
T13510 | 24033-24039 | VBN | denotes | shaped |
T13511 | 24032-24033 | HYPH | denotes | - |
T13512 | 24047-24051 | WDT | denotes | that |
T13513 | 24052-24058 | VBZ | denotes | tapers |
T13514 | 24059-24067 | RB | denotes | medially |
T13515 | 24068-24072 | IN | denotes | from |
T13516 | 24073-24076 | DT | denotes | the |
T13517 | 24090-24094 | NN | denotes | wall |
T13518 | 24077-24084 | JJ | denotes | lateral |
T13519 | 24085-24089 | NN | denotes | body |
T13520 | 24095-24097 | IN | denotes | to |
T13521 | 24098-24101 | DT | denotes | the |
T13522 | 24113-24122 | NN | denotes | mesentery |
T13523 | 24102-24112 | JJ | denotes | esophageal |
T13524 | 24123-24126 | CC | denotes | and |
T13525 | 24127-24132 | VBZ | denotes | fuses |
T13526 | 24133-24142 | RB | denotes | ventrally |
T13527 | 24143-24147 | IN | denotes | with |
T13528 | 24148-24151 | DT | denotes | the |
T13529 | 24159-24170 | NN | denotes | transversum |
T13530 | 24152-24158 | NN | denotes | septum |
T13531 | 24171-24172 | -LRB- | denotes | [ |
T13532 | 24172-24174 | CD | denotes | 42 |
T13533 | 24174-24175 | -RRB- | denotes | ] |
T13534 | 24175-24176 | . | denotes | . |
T13535 | 24176-24368 | sentence | denotes | Muscle precursors reach the PPF by E11, where they proliferate, differentiate, and then migrate toward the dorsolateral costal, sternal costal, and crural regions of the developing diaphragm. |
T13536 | 24177-24183 | NN | denotes | Muscle |
T13537 | 24184-24194 | NNS | denotes | precursors |
T13538 | 24195-24200 | VBP | denotes | reach |
T13539 | 24201-24204 | DT | denotes | the |
T13540 | 24205-24208 | NN | denotes | PPF |
T13541 | 24209-24211 | IN | denotes | by |
T13542 | 24212-24215 | NN | denotes | E11 |
T13543 | 24215-24217 | , | denotes | , |
T13544 | 24217-24222 | WRB | denotes | where |
T13545 | 24228-24239 | VBP | denotes | proliferate |
T13546 | 24223-24227 | PRP | denotes | they |
T13547 | 24239-24241 | , | denotes | , |
T13548 | 24241-24254 | VBP | denotes | differentiate |
T13549 | 24254-24256 | , | denotes | , |
T13550 | 24256-24259 | CC | denotes | and |
T13551 | 24260-24264 | RB | denotes | then |
T13552 | 24265-24272 | VBP | denotes | migrate |
T13553 | 24273-24279 | IN | denotes | toward |
T13554 | 24280-24283 | DT | denotes | the |
T13555 | 24332-24339 | NNS | denotes | regions |
T13556 | 24284-24296 | JJ | denotes | dorsolateral |
T13557 | 24297-24303 | JJ | denotes | costal |
T13558 | 24303-24305 | , | denotes | , |
T13559 | 24305-24312 | JJ | denotes | sternal |
T13560 | 24313-24319 | JJ | denotes | costal |
T13561 | 24319-24321 | , | denotes | , |
T13562 | 24321-24324 | CC | denotes | and |
T13563 | 24325-24331 | JJ | denotes | crural |
T13564 | 24340-24342 | IN | denotes | of |
T13565 | 24343-24346 | DT | denotes | the |
T13566 | 24358-24367 | NN | denotes | diaphragm |
T13567 | 24347-24357 | VBG | denotes | developing |
T13568 | 24367-24368 | . | denotes | . |
T13569 | 24368-24470 | sentence | denotes | Thus, a defect in PPF formation subsequently results in the abnormal formation of the diaphragm [43]. |
T13570 | 24369-24373 | RB | denotes | Thus |
T13571 | 24414-24421 | VBZ | denotes | results |
T13572 | 24373-24375 | , | denotes | , |
T13573 | 24375-24376 | DT | denotes | a |
T13574 | 24377-24383 | NN | denotes | defect |
T13575 | 24384-24386 | IN | denotes | in |
T13576 | 24387-24390 | NN | denotes | PPF |
T13577 | 24391-24400 | NN | denotes | formation |
T13578 | 24401-24413 | RB | denotes | subsequently |
T13579 | 24422-24424 | IN | denotes | in |
T13580 | 24425-24428 | DT | denotes | the |
T13581 | 24438-24447 | NN | denotes | formation |
T13582 | 24429-24437 | JJ | denotes | abnormal |
T13583 | 24448-24450 | IN | denotes | of |
T13584 | 24451-24454 | DT | denotes | the |
T13585 | 24455-24464 | NN | denotes | diaphragm |
T13586 | 24465-24466 | -LRB- | denotes | [ |
T13587 | 24466-24468 | CD | denotes | 43 |
T13588 | 24468-24469 | -RRB- | denotes | ] |
T13589 | 24469-24470 | . | denotes | . |
T13590 | 24470-24643 | sentence | denotes | We have shown that the Fog2 mutant does have an abnormal pattern of HGF expression in the region through which muscle precursor cells migrate onto the developing diaphragm. |
T13591 | 24471-24473 | PRP | denotes | We |
T13592 | 24479-24484 | VBN | denotes | shown |
T13593 | 24474-24478 | VBP | denotes | have |
T13594 | 24485-24489 | IN | denotes | that |
T13595 | 24511-24515 | VB | denotes | have |
T13596 | 24490-24493 | DT | denotes | the |
T13597 | 24499-24505 | NN | denotes | mutant |
T13598 | 24494-24498 | NN | denotes | Fog2 |
T13599 | 24506-24510 | VBZ | denotes | does |
T13600 | 24516-24518 | DT | denotes | an |
T13601 | 24528-24535 | NN | denotes | pattern |
T13602 | 24519-24527 | JJ | denotes | abnormal |
T13603 | 24536-24538 | IN | denotes | of |
T13604 | 24539-24542 | NN | denotes | HGF |
T13605 | 24543-24553 | NN | denotes | expression |
T13606 | 24554-24556 | IN | denotes | in |
T13607 | 24557-24560 | DT | denotes | the |
T13608 | 24561-24567 | NN | denotes | region |
T13609 | 24568-24575 | IN | denotes | through |
T13610 | 24605-24612 | VBP | denotes | migrate |
T13611 | 24576-24581 | WDT | denotes | which |
T13612 | 24582-24588 | NN | denotes | muscle |
T13613 | 24599-24604 | NNS | denotes | cells |
T13614 | 24589-24598 | NN | denotes | precursor |
T13615 | 24613-24617 | IN | denotes | onto |
T13616 | 24618-24621 | DT | denotes | the |
T13617 | 24633-24642 | NN | denotes | diaphragm |
T13618 | 24622-24632 | VBG | denotes | developing |
T13619 | 24642-24643 | . | denotes | . |
T13620 | 24643-24748 | sentence | denotes | This finding may account for the abnormally patterned muscle that develops in the Fog2 mutant diaphragm. |
T13621 | 24644-24648 | DT | denotes | This |
T13622 | 24649-24656 | NN | denotes | finding |
T13623 | 24661-24668 | VB | denotes | account |
T13624 | 24657-24660 | MD | denotes | may |
T13625 | 24669-24672 | IN | denotes | for |
T13626 | 24673-24676 | DT | denotes | the |
T13627 | 24698-24704 | NN | denotes | muscle |
T13628 | 24677-24687 | RB | denotes | abnormally |
T13629 | 24688-24697 | VBN | denotes | patterned |
T13630 | 24705-24709 | WDT | denotes | that |
T13631 | 24710-24718 | VBZ | denotes | develops |
T13632 | 24719-24721 | IN | denotes | in |
T13633 | 24722-24725 | DT | denotes | the |
T13634 | 24738-24747 | NN | denotes | diaphragm |
T13635 | 24726-24730 | NN | denotes | Fog2 |
T13636 | 24731-24737 | NN | denotes | mutant |
T13637 | 24747-24748 | . | denotes | . |
T13638 | 24748-25064 | sentence | denotes | Although Pax3 and MyoD expression is detected in the PPF, a detailed analysis of transcription factors responsible for muscle precursor cell migration and differentiation will need to be completed both in the PPF and along the pathway of muscle precursor cell migration between the PPF and the membranous diaphragm. |
T13639 | 24749-24757 | IN | denotes | Although |
T13640 | 24786-24794 | VBN | denotes | detected |
T13641 | 24758-24762 | NN | denotes | Pax3 |
T13642 | 24772-24782 | NN | denotes | expression |
T13643 | 24763-24766 | CC | denotes | and |
T13644 | 24767-24771 | NN | denotes | MyoD |
T13645 | 24783-24785 | VBZ | denotes | is |
T13646 | 24925-24929 | VB | denotes | need |
T13647 | 24795-24797 | IN | denotes | in |
T13648 | 24798-24801 | DT | denotes | the |
T13649 | 24802-24805 | NN | denotes | PPF |
T13650 | 24805-24807 | , | denotes | , |
T13651 | 24807-24808 | DT | denotes | a |
T13652 | 24818-24826 | NN | denotes | analysis |
T13653 | 24809-24817 | JJ | denotes | detailed |
T13654 | 24827-24829 | IN | denotes | of |
T13655 | 24830-24843 | NN | denotes | transcription |
T13656 | 24844-24851 | NNS | denotes | factors |
T13657 | 24852-24863 | JJ | denotes | responsible |
T13658 | 24864-24867 | IN | denotes | for |
T13659 | 24868-24874 | NN | denotes | muscle |
T13660 | 24885-24889 | NN | denotes | cell |
T13661 | 24875-24884 | NN | denotes | precursor |
T13662 | 24890-24899 | NN | denotes | migration |
T13663 | 24900-24903 | CC | denotes | and |
T13664 | 24904-24919 | NN | denotes | differentiation |
T13665 | 24920-24924 | MD | denotes | will |
T13666 | 24930-24932 | TO | denotes | to |
T13667 | 24936-24945 | VBN | denotes | completed |
T13668 | 24933-24935 | VB | denotes | be |
T13669 | 24946-24950 | CC | denotes | both |
T13670 | 24951-24953 | IN | denotes | in |
T13671 | 24954-24957 | DT | denotes | the |
T13672 | 24958-24961 | NN | denotes | PPF |
T13673 | 24962-24965 | CC | denotes | and |
T13674 | 24966-24971 | IN | denotes | along |
T13675 | 24972-24975 | DT | denotes | the |
T13676 | 24976-24983 | NN | denotes | pathway |
T13677 | 24984-24986 | IN | denotes | of |
T13678 | 24987-24993 | NN | denotes | muscle |
T13679 | 25004-25008 | NN | denotes | cell |
T13680 | 24994-25003 | NN | denotes | precursor |
T13681 | 25009-25018 | NN | denotes | migration |
T13682 | 25019-25026 | IN | denotes | between |
T13683 | 25027-25030 | DT | denotes | the |
T13684 | 25031-25034 | NN | denotes | PPF |
T13685 | 25035-25038 | CC | denotes | and |
T13686 | 25039-25042 | DT | denotes | the |
T13687 | 25054-25063 | NN | denotes | diaphragm |
T13688 | 25043-25053 | JJ | denotes | membranous |
T13689 | 25063-25064 | . | denotes | . |
T13690 | 25064-25188 | sentence | denotes | Fog2 can interact with any of the Gata factors, Gatas 1–6, as well as other transcription factors such as CoupTFII [44,45]. |
T13691 | 25065-25069 | NN | denotes | Fog2 |
T13692 | 25074-25082 | VB | denotes | interact |
T13693 | 25070-25073 | MD | denotes | can |
T13694 | 25083-25087 | IN | denotes | with |
T13695 | 25088-25091 | DT | denotes | any |
T13696 | 25092-25094 | IN | denotes | of |
T13697 | 25095-25098 | DT | denotes | the |
T13698 | 25104-25111 | NNS | denotes | factors |
T13699 | 25099-25103 | NN | denotes | Gata |
T13700 | 25111-25113 | , | denotes | , |
T13701 | 25113-25118 | NNS | denotes | Gatas |
T13702 | 25119-25120 | CD | denotes | 1 |
T13703 | 25120-25121 | SYM | denotes | – |
T13704 | 25121-25122 | CD | denotes | 6 |
T13705 | 25122-25124 | , | denotes | , |
T13706 | 25124-25126 | RB | denotes | as |
T13707 | 25132-25134 | IN | denotes | as |
T13708 | 25127-25131 | RB | denotes | well |
T13709 | 25135-25140 | JJ | denotes | other |
T13710 | 25155-25162 | NNS | denotes | factors |
T13711 | 25141-25154 | NN | denotes | transcription |
T13712 | 25163-25167 | JJ | denotes | such |
T13713 | 25168-25170 | IN | denotes | as |
T13714 | 25171-25179 | NN | denotes | CoupTFII |
T13715 | 25180-25181 | -LRB- | denotes | [ |
T13716 | 25184-25186 | CD | denotes | 45 |
T13717 | 25181-25183 | CD | denotes | 44 |
T13718 | 25183-25184 | , | denotes | , |
T13719 | 25186-25187 | -RRB- | denotes | ] |
T13720 | 25187-25188 | . | denotes | . |
T13721 | 25188-25366 | sentence | denotes | It is known that a Fog2–Gata4 interaction is critical for normal cardiac and gonadal development, but interacting factors in the lung and diaphragm have not yet been determined. |
T13722 | 25189-25191 | PRP | denotes | It |
T13723 | 25195-25200 | VBN | denotes | known |
T13724 | 25192-25194 | VBZ | denotes | is |
T13725 | 25201-25205 | IN | denotes | that |
T13726 | 25231-25233 | VBZ | denotes | is |
T13727 | 25206-25207 | DT | denotes | a |
T13728 | 25219-25230 | NN | denotes | interaction |
T13729 | 25208-25212 | NN | denotes | Fog2 |
T13730 | 25213-25218 | NN | denotes | Gata4 |
T13731 | 25212-25213 | HYPH | denotes | – |
T13732 | 25234-25242 | JJ | denotes | critical |
T13733 | 25243-25246 | IN | denotes | for |
T13734 | 25247-25253 | JJ | denotes | normal |
T13735 | 25274-25285 | NN | denotes | development |
T13736 | 25254-25261 | JJ | denotes | cardiac |
T13737 | 25262-25265 | CC | denotes | and |
T13738 | 25266-25273 | JJ | denotes | gonadal |
T13739 | 25285-25287 | , | denotes | , |
T13740 | 25287-25290 | CC | denotes | but |
T13741 | 25291-25302 | VBG | denotes | interacting |
T13742 | 25303-25310 | NNS | denotes | factors |
T13743 | 25355-25365 | VBN | denotes | determined |
T13744 | 25311-25313 | IN | denotes | in |
T13745 | 25314-25317 | DT | denotes | the |
T13746 | 25318-25322 | NN | denotes | lung |
T13747 | 25323-25326 | CC | denotes | and |
T13748 | 25327-25336 | NN | denotes | diaphragm |
T13749 | 25337-25341 | VBP | denotes | have |
T13750 | 25342-25345 | RB | denotes | not |
T13751 | 25346-25349 | RB | denotes | yet |
T13752 | 25350-25354 | VBN | denotes | been |
T13753 | 25365-25366 | . | denotes | . |
T13754 | 25366-25483 | sentence | denotes | The severity of pulmonary hypoplasia in the patient we report was out of proportion to that of the diaphragm defect. |
T13755 | 25367-25370 | DT | denotes | The |
T13756 | 25371-25379 | NN | denotes | severity |
T13757 | 25429-25432 | VBD | denotes | was |
T13758 | 25380-25382 | IN | denotes | of |
T13759 | 25383-25392 | JJ | denotes | pulmonary |
T13760 | 25393-25403 | NN | denotes | hypoplasia |
T13761 | 25404-25406 | IN | denotes | in |
T13762 | 25407-25410 | DT | denotes | the |
T13763 | 25411-25418 | NN | denotes | patient |
T13764 | 25419-25421 | PRP | denotes | we |
T13765 | 25422-25428 | VBP | denotes | report |
T13766 | 25433-25436 | IN | denotes | out |
T13767 | 25437-25439 | IN | denotes | of |
T13768 | 25440-25450 | NN | denotes | proportion |
T13769 | 25451-25453 | IN | denotes | to |
T13770 | 25454-25458 | DT | denotes | that |
T13771 | 25459-25461 | IN | denotes | of |
T13772 | 25462-25465 | DT | denotes | the |
T13773 | 25476-25482 | NN | denotes | defect |
T13774 | 25466-25475 | NN | denotes | diaphragm |
T13775 | 25482-25483 | . | denotes | . |
T13776 | 25483-25737 | sentence | denotes | Pulmonary hypoplasia is associated with abnormal diaphragmatic anatomy or function, and is known to occur as a secondary developmental defect in models of diaphragmatic dysfunction such as complete amuscularization [17] or phrenic nerve disruption [46]. |
T13777 | 25484-25493 | JJ | denotes | Pulmonary |
T13778 | 25494-25504 | NN | denotes | hypoplasia |
T13779 | 25505-25507 | VBZ | denotes | is |
T13780 | 25508-25518 | JJ | denotes | associated |
T13781 | 25519-25523 | IN | denotes | with |
T13782 | 25524-25532 | JJ | denotes | abnormal |
T13783 | 25547-25554 | NN | denotes | anatomy |
T13784 | 25533-25546 | JJ | denotes | diaphragmatic |
T13785 | 25555-25557 | CC | denotes | or |
T13786 | 25558-25566 | NN | denotes | function |
T13787 | 25566-25568 | , | denotes | , |
T13788 | 25568-25571 | CC | denotes | and |
T13789 | 25572-25574 | VBZ | denotes | is |
T13790 | 25575-25580 | VBN | denotes | known |
T13791 | 25581-25583 | TO | denotes | to |
T13792 | 25584-25589 | VB | denotes | occur |
T13793 | 25590-25592 | IN | denotes | as |
T13794 | 25593-25594 | DT | denotes | a |
T13795 | 25619-25625 | NN | denotes | defect |
T13796 | 25595-25604 | JJ | denotes | secondary |
T13797 | 25605-25618 | JJ | denotes | developmental |
T13798 | 25626-25628 | IN | denotes | in |
T13799 | 25629-25635 | NNS | denotes | models |
T13800 | 25636-25638 | IN | denotes | of |
T13801 | 25639-25652 | JJ | denotes | diaphragmatic |
T13802 | 25653-25664 | NN | denotes | dysfunction |
T13803 | 25665-25669 | JJ | denotes | such |
T13804 | 25670-25672 | IN | denotes | as |
T13805 | 25673-25681 | JJ | denotes | complete |
T13806 | 25682-25698 | NN | denotes | amuscularization |
T13807 | 25699-25700 | -LRB- | denotes | [ |
T13808 | 25700-25702 | CD | denotes | 17 |
T13809 | 25702-25703 | -RRB- | denotes | ] |
T13810 | 25704-25706 | CC | denotes | or |
T13811 | 25707-25714 | JJ | denotes | phrenic |
T13812 | 25715-25720 | NN | denotes | nerve |
T13813 | 25721-25731 | NN | denotes | disruption |
T13814 | 25732-25733 | -LRB- | denotes | [ |
T13815 | 25733-25735 | CD | denotes | 46 |
T13816 | 25735-25736 | -RRB- | denotes | ] |
T13817 | 25736-25737 | . | denotes | . |
T13818 | 25737-25843 | sentence | denotes | It occurs in a surgical model of CDH in which a hernia is physically created in an in utero lamb [47,48]. |
T13819 | 25738-25740 | PRP | denotes | It |
T13820 | 25741-25747 | VBZ | denotes | occurs |
T13821 | 25748-25750 | IN | denotes | in |
T13822 | 25751-25752 | DT | denotes | a |
T13823 | 25762-25767 | NN | denotes | model |
T13824 | 25753-25761 | JJ | denotes | surgical |
T13825 | 25768-25770 | IN | denotes | of |
T13826 | 25771-25774 | NN | denotes | CDH |
T13827 | 25775-25777 | IN | denotes | in |
T13828 | 25807-25814 | VBN | denotes | created |
T13829 | 25778-25783 | WDT | denotes | which |
T13830 | 25784-25785 | DT | denotes | a |
T13831 | 25786-25792 | NN | denotes | hernia |
T13832 | 25793-25795 | VBZ | denotes | is |
T13833 | 25796-25806 | RB | denotes | physically |
T13834 | 25815-25817 | IN | denotes | in |
T13835 | 25818-25820 | DT | denotes | an |
T13836 | 25830-25834 | NN | denotes | lamb |
T13837 | 25821-25823 | FW | denotes | in |
T13838 | 25824-25829 | FW | denotes | utero |
T13839 | 25835-25836 | -LRB- | denotes | [ |
T13840 | 25839-25841 | CD | denotes | 48 |
T13841 | 25836-25838 | CD | denotes | 47 |
T13842 | 25838-25839 | , | denotes | , |
T13843 | 25841-25842 | -RRB- | denotes | ] |
T13844 | 25842-25843 | . | denotes | . |
T13845 | 25843-26123 | sentence | denotes | However, the possibility that primary pulmonary developmental abnormalities occur with, rather than secondary to, diaphragmatic defects has been suggested by others based on a teratogenic model of CDH [49–51] and has long been suspected by clinicians who care for these patients. |
T13846 | 25844-25851 | RB | denotes | However |
T13847 | 25989-25998 | VBN | denotes | suggested |
T13848 | 25851-25853 | , | denotes | , |
T13849 | 25853-25856 | DT | denotes | the |
T13850 | 25857-25868 | NN | denotes | possibility |
T13851 | 25869-25873 | IN | denotes | that |
T13852 | 25920-25925 | VBP | denotes | occur |
T13853 | 25874-25881 | JJ | denotes | primary |
T13854 | 25906-25919 | NNS | denotes | abnormalities |
T13855 | 25882-25891 | JJ | denotes | pulmonary |
T13856 | 25892-25905 | JJ | denotes | developmental |
T13857 | 25926-25930 | IN | denotes | with |
T13858 | 25930-25932 | , | denotes | , |
T13859 | 25932-25938 | RB | denotes | rather |
T13860 | 25939-25943 | IN | denotes | than |
T13861 | 25944-25953 | RB | denotes | secondary |
T13862 | 25954-25956 | IN | denotes | to |
T13863 | 25956-25958 | , | denotes | , |
T13864 | 25958-25971 | JJ | denotes | diaphragmatic |
T13865 | 25972-25979 | NNS | denotes | defects |
T13866 | 25980-25983 | VBZ | denotes | has |
T13867 | 25984-25988 | VBN | denotes | been |
T13868 | 25999-26001 | IN | denotes | by |
T13869 | 26002-26008 | NNS | denotes | others |
T13870 | 26009-26014 | VBN | denotes | based |
T13871 | 26015-26017 | IN | denotes | on |
T13872 | 26018-26019 | DT | denotes | a |
T13873 | 26032-26037 | NN | denotes | model |
T13874 | 26020-26031 | JJ | denotes | teratogenic |
T13875 | 26038-26040 | IN | denotes | of |
T13876 | 26041-26044 | NN | denotes | CDH |
T13877 | 26045-26046 | -LRB- | denotes | [ |
T13878 | 26046-26048 | CD | denotes | 49 |
T13879 | 26048-26049 | SYM | denotes | – |
T13880 | 26049-26051 | CD | denotes | 51 |
T13881 | 26051-26052 | -RRB- | denotes | ] |
T13882 | 26053-26056 | CC | denotes | and |
T13883 | 26057-26060 | VBZ | denotes | has |
T13884 | 26071-26080 | VBN | denotes | suspected |
T13885 | 26061-26065 | RB | denotes | long |
T13886 | 26066-26070 | VBN | denotes | been |
T13887 | 26081-26083 | IN | denotes | by |
T13888 | 26084-26094 | NNS | denotes | clinicians |
T13889 | 26095-26098 | WP | denotes | who |
T13890 | 26099-26103 | VBP | denotes | care |
T13891 | 26104-26107 | IN | denotes | for |
T13892 | 26108-26113 | DT | denotes | these |
T13893 | 26114-26122 | NNS | denotes | patients |
T13894 | 26122-26123 | . | denotes | . |
T13895 | 26123-26317 | sentence | denotes | In addition, the high incidence of lobar abnormalities associated with CDH [52] supports the possibility that this disorder can be associated with a primary developmental pulmonary abnormality. |
T13896 | 26124-26126 | IN | denotes | In |
T13897 | 26204-26212 | VBZ | denotes | supports |
T13898 | 26127-26135 | NN | denotes | addition |
T13899 | 26135-26137 | , | denotes | , |
T13900 | 26137-26140 | DT | denotes | the |
T13901 | 26146-26155 | NN | denotes | incidence |
T13902 | 26141-26145 | JJ | denotes | high |
T13903 | 26156-26158 | IN | denotes | of |
T13904 | 26159-26164 | NN | denotes | lobar |
T13905 | 26165-26178 | NNS | denotes | abnormalities |
T13906 | 26179-26189 | JJ | denotes | associated |
T13907 | 26190-26194 | IN | denotes | with |
T13908 | 26195-26198 | NN | denotes | CDH |
T13909 | 26199-26200 | -LRB- | denotes | [ |
T13910 | 26200-26202 | CD | denotes | 52 |
T13911 | 26202-26203 | -RRB- | denotes | ] |
T13912 | 26213-26216 | DT | denotes | the |
T13913 | 26217-26228 | NN | denotes | possibility |
T13914 | 26229-26233 | IN | denotes | that |
T13915 | 26255-26265 | VBN | denotes | associated |
T13916 | 26234-26238 | DT | denotes | this |
T13917 | 26239-26247 | NN | denotes | disorder |
T13918 | 26248-26251 | MD | denotes | can |
T13919 | 26252-26254 | VB | denotes | be |
T13920 | 26266-26270 | IN | denotes | with |
T13921 | 26271-26272 | DT | denotes | a |
T13922 | 26305-26316 | NN | denotes | abnormality |
T13923 | 26273-26280 | JJ | denotes | primary |
T13924 | 26281-26294 | JJ | denotes | developmental |
T13925 | 26295-26304 | JJ | denotes | pulmonary |
T13926 | 26316-26317 | . | denotes | . |
T13927 | 26317-26518 | sentence | denotes | Our analysis of mice carrying mutations of Fog2 proves that there is a primary defect in lung development that results in specific loss of the accessory lobe and partial loss of the right middle lobe. |
T13928 | 26318-26321 | PRP$ | denotes | Our |
T13929 | 26322-26330 | NN | denotes | analysis |
T13930 | 26366-26372 | VBZ | denotes | proves |
T13931 | 26331-26333 | IN | denotes | of |
T13932 | 26334-26338 | NNS | denotes | mice |
T13933 | 26339-26347 | VBG | denotes | carrying |
T13934 | 26348-26357 | NNS | denotes | mutations |
T13935 | 26358-26360 | IN | denotes | of |
T13936 | 26361-26365 | NN | denotes | Fog2 |
T13937 | 26373-26377 | IN | denotes | that |
T13938 | 26384-26386 | VBZ | denotes | is |
T13939 | 26378-26383 | EX | denotes | there |
T13940 | 26387-26388 | DT | denotes | a |
T13941 | 26397-26403 | NN | denotes | defect |
T13942 | 26389-26396 | JJ | denotes | primary |
T13943 | 26404-26406 | IN | denotes | in |
T13944 | 26407-26411 | NN | denotes | lung |
T13945 | 26412-26423 | NN | denotes | development |
T13946 | 26424-26428 | WDT | denotes | that |
T13947 | 26429-26436 | VBZ | denotes | results |
T13948 | 26437-26439 | IN | denotes | in |
T13949 | 26440-26448 | JJ | denotes | specific |
T13950 | 26449-26453 | NN | denotes | loss |
T13951 | 26454-26456 | IN | denotes | of |
T13952 | 26457-26460 | DT | denotes | the |
T13953 | 26471-26475 | NN | denotes | lobe |
T13954 | 26461-26470 | JJ | denotes | accessory |
T13955 | 26476-26479 | CC | denotes | and |
T13956 | 26480-26487 | JJ | denotes | partial |
T13957 | 26488-26492 | NN | denotes | loss |
T13958 | 26493-26495 | IN | denotes | of |
T13959 | 26496-26499 | DT | denotes | the |
T13960 | 26513-26517 | NN | denotes | lobe |
T13961 | 26500-26505 | JJ | denotes | right |
T13962 | 26506-26512 | JJ | denotes | middle |
T13963 | 26517-26518 | . | denotes | . |
T13964 | 26518-26621 | sentence | denotes | The specific lobar defects prompted us to evaluate Fog2 expression at the time of early lobar budding. |
T13965 | 26519-26522 | DT | denotes | The |
T13966 | 26538-26545 | NNS | denotes | defects |
T13967 | 26523-26531 | JJ | denotes | specific |
T13968 | 26532-26537 | NN | denotes | lobar |
T13969 | 26546-26554 | VBD | denotes | prompted |
T13970 | 26555-26557 | PRP | denotes | us |
T13971 | 26558-26560 | TO | denotes | to |
T13972 | 26561-26569 | VB | denotes | evaluate |
T13973 | 26570-26574 | NN | denotes | Fog2 |
T13974 | 26575-26585 | NN | denotes | expression |
T13975 | 26586-26588 | IN | denotes | at |
T13976 | 26589-26592 | DT | denotes | the |
T13977 | 26593-26597 | NN | denotes | time |
T13978 | 26598-26600 | IN | denotes | of |
T13979 | 26601-26606 | JJ | denotes | early |
T13980 | 26613-26620 | NN | denotes | budding |
T13981 | 26607-26612 | NN | denotes | lobar |
T13982 | 26620-26621 | . | denotes | . |
T13983 | 26621-26854 | sentence | denotes | While Fog2 expression is diffuse in the pulmonary mesenchyme after lobar structure is well established (E12.5), it is more focally expressed in the mesenchyme surrounding the right middle lobe and accessory buds as these lobes form. |
T13984 | 26622-26627 | IN | denotes | While |
T13985 | 26644-26646 | VBZ | denotes | is |
T13986 | 26628-26632 | NN | denotes | Fog2 |
T13987 | 26633-26643 | NN | denotes | expression |
T13988 | 26753-26762 | VBN | denotes | expressed |
T13989 | 26647-26654 | JJ | denotes | diffuse |
T13990 | 26655-26657 | IN | denotes | in |
T13991 | 26658-26661 | DT | denotes | the |
T13992 | 26672-26682 | NN | denotes | mesenchyme |
T13993 | 26662-26671 | JJ | denotes | pulmonary |
T13994 | 26683-26688 | IN | denotes | after |
T13995 | 26705-26707 | VBZ | denotes | is |
T13996 | 26689-26694 | NN | denotes | lobar |
T13997 | 26695-26704 | NN | denotes | structure |
T13998 | 26708-26712 | RB | denotes | well |
T13999 | 26713-26724 | VBN | denotes | established |
T14000 | 26725-26726 | -LRB- | denotes | ( |
T14001 | 26726-26731 | NN | denotes | E12.5 |
T14002 | 26731-26732 | -RRB- | denotes | ) |
T14003 | 26732-26734 | , | denotes | , |
T14004 | 26734-26736 | PRP | denotes | it |
T14005 | 26737-26739 | VBZ | denotes | is |
T14006 | 26740-26744 | RBR | denotes | more |
T14007 | 26745-26752 | RB | denotes | focally |
T14008 | 26763-26765 | IN | denotes | in |
T14009 | 26766-26769 | DT | denotes | the |
T14010 | 26770-26780 | NN | denotes | mesenchyme |
T14011 | 26781-26792 | VBG | denotes | surrounding |
T14012 | 26793-26796 | DT | denotes | the |
T14013 | 26810-26814 | NN | denotes | lobe |
T14014 | 26797-26802 | JJ | denotes | right |
T14015 | 26803-26809 | JJ | denotes | middle |
T14016 | 26815-26818 | CC | denotes | and |
T14017 | 26819-26828 | JJ | denotes | accessory |
T14018 | 26829-26833 | NNS | denotes | buds |
T14019 | 26834-26836 | IN | denotes | as |
T14020 | 26849-26853 | VBP | denotes | form |
T14021 | 26837-26842 | DT | denotes | these |
T14022 | 26843-26848 | NNS | denotes | lobes |
T14023 | 26853-26854 | . | denotes | . |
T14024 | 26854-27014 | sentence | denotes | This matches the phenotype of right middle lobe and accessory lobe loss, and suggests that Fog2 has a specific patterning role in establishment of these lobes. |
T14025 | 26855-26859 | DT | denotes | This |
T14026 | 26860-26867 | VBZ | denotes | matches |
T14027 | 26868-26871 | DT | denotes | the |
T14028 | 26872-26881 | NN | denotes | phenotype |
T14029 | 26882-26884 | IN | denotes | of |
T14030 | 26885-26890 | JJ | denotes | right |
T14031 | 26898-26902 | NN | denotes | lobe |
T14032 | 26891-26897 | JJ | denotes | middle |
T14033 | 26922-26926 | NN | denotes | loss |
T14034 | 26903-26906 | CC | denotes | and |
T14035 | 26907-26916 | JJ | denotes | accessory |
T14036 | 26917-26921 | NN | denotes | lobe |
T14037 | 26926-26928 | , | denotes | , |
T14038 | 26928-26931 | CC | denotes | and |
T14039 | 26932-26940 | VBZ | denotes | suggests |
T14040 | 26941-26945 | IN | denotes | that |
T14041 | 26951-26954 | VBZ | denotes | has |
T14042 | 26946-26950 | NN | denotes | Fog2 |
T14043 | 26955-26956 | DT | denotes | a |
T14044 | 26977-26981 | NN | denotes | role |
T14045 | 26957-26965 | JJ | denotes | specific |
T14046 | 26966-26976 | NN | denotes | patterning |
T14047 | 26982-26984 | IN | denotes | in |
T14048 | 26985-26998 | NN | denotes | establishment |
T14049 | 26999-27001 | IN | denotes | of |
T14050 | 27002-27007 | DT | denotes | these |
T14051 | 27008-27013 | NNS | denotes | lobes |
T14052 | 27013-27014 | . | denotes | . |
T14053 | 27014-27186 | sentence | denotes | It is less clear whether loss of Fog2 results in a global branching defect, as Fog2 lungs appear to have a slight developmental delay, which could result from many causes. |
T14054 | 27015-27017 | PRP | denotes | It |
T14055 | 27018-27020 | VBZ | denotes | is |
T14056 | 27021-27025 | RBR | denotes | less |
T14057 | 27026-27031 | JJ | denotes | clear |
T14058 | 27032-27039 | IN | denotes | whether |
T14059 | 27053-27060 | VBZ | denotes | results |
T14060 | 27040-27044 | NN | denotes | loss |
T14061 | 27045-27047 | IN | denotes | of |
T14062 | 27048-27052 | NN | denotes | Fog2 |
T14063 | 27061-27063 | IN | denotes | in |
T14064 | 27064-27065 | DT | denotes | a |
T14065 | 27083-27089 | NN | denotes | defect |
T14066 | 27066-27072 | JJ | denotes | global |
T14067 | 27073-27082 | NN | denotes | branching |
T14068 | 27089-27091 | , | denotes | , |
T14069 | 27091-27093 | IN | denotes | as |
T14070 | 27105-27111 | VBP | denotes | appear |
T14071 | 27094-27098 | NN | denotes | Fog2 |
T14072 | 27099-27104 | NNS | denotes | lungs |
T14073 | 27112-27114 | TO | denotes | to |
T14074 | 27115-27119 | VB | denotes | have |
T14075 | 27120-27121 | DT | denotes | a |
T14076 | 27143-27148 | NN | denotes | delay |
T14077 | 27122-27128 | JJ | denotes | slight |
T14078 | 27129-27142 | JJ | denotes | developmental |
T14079 | 27148-27150 | , | denotes | , |
T14080 | 27150-27155 | WDT | denotes | which |
T14081 | 27162-27168 | VB | denotes | result |
T14082 | 27156-27161 | MD | denotes | could |
T14083 | 27169-27173 | IN | denotes | from |
T14084 | 27174-27178 | JJ | denotes | many |
T14085 | 27179-27185 | NNS | denotes | causes |
T14086 | 27185-27186 | . | denotes | . |
T14087 | 27186-27349 | sentence | denotes | Cultured Fog2 lungs do develop an intricate branching pattern in the unaffected lobes that appears similar in the pattern to wild-type lungs after 5 d in culture. |
T14088 | 27187-27195 | VBN | denotes | Cultured |
T14089 | 27201-27206 | NNS | denotes | lungs |
T14090 | 27196-27200 | NN | denotes | Fog2 |
T14091 | 27210-27217 | VB | denotes | develop |
T14092 | 27207-27209 | VBP | denotes | do |
T14093 | 27218-27220 | DT | denotes | an |
T14094 | 27241-27248 | NN | denotes | pattern |
T14095 | 27221-27230 | JJ | denotes | intricate |
T14096 | 27231-27240 | NN | denotes | branching |
T14097 | 27249-27251 | IN | denotes | in |
T14098 | 27252-27255 | DT | denotes | the |
T14099 | 27267-27272 | NNS | denotes | lobes |
T14100 | 27256-27266 | JJ | denotes | unaffected |
T14101 | 27273-27277 | WDT | denotes | that |
T14102 | 27278-27285 | VBZ | denotes | appears |
T14103 | 27286-27293 | JJ | denotes | similar |
T14104 | 27294-27296 | IN | denotes | in |
T14105 | 27297-27300 | DT | denotes | the |
T14106 | 27301-27308 | NN | denotes | pattern |
T14107 | 27309-27311 | IN | denotes | to |
T14108 | 27312-27316 | JJ | denotes | wild |
T14109 | 27317-27321 | NN | denotes | type |
T14110 | 27316-27317 | HYPH | denotes | - |
T14111 | 27322-27327 | NNS | denotes | lungs |
T14112 | 27328-27333 | IN | denotes | after |
T14113 | 27334-27335 | CD | denotes | 5 |
T14114 | 27336-27337 | NN | denotes | d |
T14115 | 27338-27340 | IN | denotes | in |
T14116 | 27341-27348 | NN | denotes | culture |
T14117 | 27348-27349 | . | denotes | . |
T14118 | 27349-27507 | sentence | denotes | In this report, we show that a mutation of Fog2 in the mouse causes the phenotype of abnormal diaphragmatic muscularization and primary pulmonary hypoplasia. |
T14119 | 27350-27352 | IN | denotes | In |
T14120 | 27369-27373 | VBP | denotes | show |
T14121 | 27353-27357 | DT | denotes | this |
T14122 | 27358-27364 | NN | denotes | report |
T14123 | 27364-27366 | , | denotes | , |
T14124 | 27366-27368 | PRP | denotes | we |
T14125 | 27374-27378 | IN | denotes | that |
T14126 | 27411-27417 | VBZ | denotes | causes |
T14127 | 27379-27380 | DT | denotes | a |
T14128 | 27381-27389 | NN | denotes | mutation |
T14129 | 27390-27392 | IN | denotes | of |
T14130 | 27393-27397 | NN | denotes | Fog2 |
T14131 | 27398-27400 | IN | denotes | in |
T14132 | 27401-27404 | DT | denotes | the |
T14133 | 27405-27410 | NN | denotes | mouse |
T14134 | 27418-27421 | DT | denotes | the |
T14135 | 27422-27431 | NN | denotes | phenotype |
T14136 | 27432-27434 | IN | denotes | of |
T14137 | 27435-27443 | JJ | denotes | abnormal |
T14138 | 27458-27473 | NN | denotes | muscularization |
T14139 | 27444-27457 | JJ | denotes | diaphragmatic |
T14140 | 27474-27477 | CC | denotes | and |
T14141 | 27478-27485 | JJ | denotes | primary |
T14142 | 27496-27506 | NN | denotes | hypoplasia |
T14143 | 27486-27495 | JJ | denotes | pulmonary |
T14144 | 27506-27507 | . | denotes | . |
T14145 | 27507-27644 | sentence | denotes | We furthermore demonstrate that a mutation in this gene is associated with a lethal defect in lung and diaphragm development in a child. |
T14146 | 27508-27510 | PRP | denotes | We |
T14147 | 27523-27534 | VBP | denotes | demonstrate |
T14148 | 27511-27522 | RB | denotes | furthermore |
T14149 | 27535-27539 | IN | denotes | that |
T14150 | 27564-27566 | VBZ | denotes | is |
T14151 | 27540-27541 | DT | denotes | a |
T14152 | 27542-27550 | NN | denotes | mutation |
T14153 | 27551-27553 | IN | denotes | in |
T14154 | 27554-27558 | DT | denotes | this |
T14155 | 27559-27563 | NN | denotes | gene |
T14156 | 27567-27577 | JJ | denotes | associated |
T14157 | 27578-27582 | IN | denotes | with |
T14158 | 27583-27584 | DT | denotes | a |
T14159 | 27592-27598 | NN | denotes | defect |
T14160 | 27585-27591 | JJ | denotes | lethal |
T14161 | 27599-27601 | IN | denotes | in |
T14162 | 27602-27606 | NN | denotes | lung |
T14163 | 27621-27632 | NN | denotes | development |
T14164 | 27607-27610 | CC | denotes | and |
T14165 | 27611-27620 | NN | denotes | diaphragm |
T14166 | 27633-27635 | IN | denotes | in |
T14167 | 27636-27637 | DT | denotes | a |
T14168 | 27638-27643 | NN | denotes | child |
T14169 | 27643-27644 | . | denotes | . |
T14170 | 27644-27827 | sentence | denotes | It is notable that, despite extensive analysis of Fog2 biology and the generation of a Fog2 knock-out mouse, its role in diaphragm and lung development was previously not recognized. |
T14171 | 27645-27647 | PRP | denotes | It |
T14172 | 27648-27650 | VBZ | denotes | is |
T14173 | 27651-27658 | JJ | denotes | notable |
T14174 | 27659-27663 | IN | denotes | that |
T14175 | 27816-27826 | VBN | denotes | recognized |
T14176 | 27663-27665 | , | denotes | , |
T14177 | 27665-27672 | IN | denotes | despite |
T14178 | 27673-27682 | JJ | denotes | extensive |
T14179 | 27683-27691 | NN | denotes | analysis |
T14180 | 27692-27694 | IN | denotes | of |
T14181 | 27695-27699 | NN | denotes | Fog2 |
T14182 | 27700-27707 | NN | denotes | biology |
T14183 | 27708-27711 | CC | denotes | and |
T14184 | 27712-27715 | DT | denotes | the |
T14185 | 27716-27726 | NN | denotes | generation |
T14186 | 27727-27729 | IN | denotes | of |
T14187 | 27730-27731 | DT | denotes | a |
T14188 | 27747-27752 | NN | denotes | mouse |
T14189 | 27732-27736 | NN | denotes | Fog2 |
T14190 | 27737-27742 | VB | denotes | knock |
T14191 | 27742-27743 | HYPH | denotes | - |
T14192 | 27743-27746 | RP | denotes | out |
T14193 | 27752-27754 | , | denotes | , |
T14194 | 27754-27757 | PRP$ | denotes | its |
T14195 | 27758-27762 | NN | denotes | role |
T14196 | 27763-27765 | IN | denotes | in |
T14197 | 27766-27775 | NN | denotes | diaphragm |
T14198 | 27785-27796 | NN | denotes | development |
T14199 | 27776-27779 | CC | denotes | and |
T14200 | 27780-27784 | NN | denotes | lung |
T14201 | 27797-27800 | VBD | denotes | was |
T14202 | 27801-27811 | RB | denotes | previously |
T14203 | 27812-27815 | RB | denotes | not |
T14204 | 27826-27827 | . | denotes | . |
T14205 | 27827-28030 | sentence | denotes | It is only as a consequence of phenotype-driven analyses such as those we are pursuing that one has the opportunity to assay all of the potential molecular derangements that may result in human disease. |
T14206 | 27828-27830 | PRP | denotes | It |
T14207 | 27831-27833 | VBZ | denotes | is |
T14208 | 27834-27838 | RB | denotes | only |
T14209 | 27839-27841 | IN | denotes | as |
T14210 | 27842-27843 | DT | denotes | a |
T14211 | 27844-27855 | NN | denotes | consequence |
T14212 | 27856-27858 | IN | denotes | of |
T14213 | 27859-27868 | NN | denotes | phenotype |
T14214 | 27869-27875 | VBN | denotes | driven |
T14215 | 27868-27869 | HYPH | denotes | - |
T14216 | 27876-27884 | NNS | denotes | analyses |
T14217 | 27885-27889 | JJ | denotes | such |
T14218 | 27890-27892 | IN | denotes | as |
T14219 | 27893-27898 | DT | denotes | those |
T14220 | 27899-27901 | PRP | denotes | we |
T14221 | 27906-27914 | VBG | denotes | pursuing |
T14222 | 27902-27905 | VBP | denotes | are |
T14223 | 27915-27919 | IN | denotes | that |
T14224 | 27924-27927 | VBZ | denotes | has |
T14225 | 27920-27923 | PRP | denotes | one |
T14226 | 27928-27931 | DT | denotes | the |
T14227 | 27932-27943 | NN | denotes | opportunity |
T14228 | 27944-27946 | TO | denotes | to |
T14229 | 27947-27952 | VB | denotes | assay |
T14230 | 27953-27956 | DT | denotes | all |
T14231 | 27957-27959 | IN | denotes | of |
T14232 | 27960-27963 | DT | denotes | the |
T14233 | 27984-27996 | NNS | denotes | derangements |
T14234 | 27964-27973 | JJ | denotes | potential |
T14235 | 27974-27983 | JJ | denotes | molecular |
T14236 | 27997-28001 | WDT | denotes | that |
T14237 | 28006-28012 | VB | denotes | result |
T14238 | 28002-28005 | MD | denotes | may |
T14239 | 28013-28015 | IN | denotes | in |
T14240 | 28016-28021 | JJ | denotes | human |
T14241 | 28022-28029 | NN | denotes | disease |
T14242 | 28029-28030 | . | denotes | . |
T14396 | 28325-28332 | JJ | denotes | Genetic |
T14397 | 28333-28340 | NN | denotes | mapping |
T14398 | 28341-28343 | IN | denotes | of |
T14399 | 28344-28347 | DT | denotes | the |
T14400 | 28354-28362 | NN | denotes | mutation |
T14401 | 28348-28353 | NN | denotes | mouse |
T14402 | 28363-28366 | NN | denotes | lil |
T14403 | 28366-28367 | . | denotes | . |
T14404 | 28367-28424 | sentence | denotes | The lil mutation was identified as described in results. |
T14405 | 28368-28371 | DT | denotes | The |
T14406 | 28376-28384 | NN | denotes | mutation |
T14407 | 28372-28375 | NN | denotes | lil |
T14408 | 28389-28399 | VBN | denotes | identified |
T14409 | 28385-28388 | VBD | denotes | was |
T14410 | 28400-28402 | IN | denotes | as |
T14411 | 28403-28412 | VBN | denotes | described |
T14412 | 28413-28415 | IN | denotes | in |
T14413 | 28416-28423 | NNS | denotes | results |
T14414 | 28423-28424 | . | denotes | . |
T14415 | 28424-28561 | sentence | denotes | Wild-type FVB/N and C57BL/6J mice used for genetic crosses were obtained from the Jackson Laboratory (Bar Harbor, Maine, United States). |
T14416 | 28425-28429 | JJ | denotes | Wild |
T14417 | 28430-28434 | NN | denotes | type |
T14418 | 28429-28430 | HYPH | denotes | - |
T14419 | 28454-28458 | NNS | denotes | mice |
T14420 | 28435-28438 | NN | denotes | FVB |
T14421 | 28439-28440 | NN | denotes | N |
T14422 | 28438-28439 | HYPH | denotes | / |
T14423 | 28441-28444 | CC | denotes | and |
T14424 | 28445-28450 | NN | denotes | C57BL |
T14425 | 28451-28453 | NN | denotes | 6J |
T14426 | 28450-28451 | HYPH | denotes | / |
T14427 | 28489-28497 | VBN | denotes | obtained |
T14428 | 28459-28463 | VBN | denotes | used |
T14429 | 28464-28467 | IN | denotes | for |
T14430 | 28468-28475 | JJ | denotes | genetic |
T14431 | 28476-28483 | NNS | denotes | crosses |
T14432 | 28484-28488 | VBD | denotes | were |
T14433 | 28498-28502 | IN | denotes | from |
T14434 | 28503-28506 | DT | denotes | the |
T14435 | 28515-28525 | NNP | denotes | Laboratory |
T14436 | 28507-28514 | NNP | denotes | Jackson |
T14437 | 28526-28527 | -LRB- | denotes | ( |
T14438 | 28531-28537 | NNP | denotes | Harbor |
T14439 | 28527-28530 | NNP | denotes | Bar |
T14440 | 28537-28539 | , | denotes | , |
T14441 | 28539-28544 | NNP | denotes | Maine |
T14442 | 28544-28546 | , | denotes | , |
T14443 | 28546-28552 | NNP | denotes | United |
T14444 | 28553-28559 | NNP | denotes | States |
T14445 | 28559-28560 | -RRB- | denotes | ) |
T14446 | 28560-28561 | . | denotes | . |
T14447 | 28561-28676 | sentence | denotes | Mice carrying a null mutation of Fog2 generated by gene targeting [16] were the generous gift of Dr. Stuart Orkin. |
T14448 | 28562-28566 | NNS | denotes | Mice |
T14449 | 28633-28637 | VBD | denotes | were |
T14450 | 28567-28575 | VBG | denotes | carrying |
T14451 | 28576-28577 | DT | denotes | a |
T14452 | 28583-28591 | NN | denotes | mutation |
T14453 | 28578-28582 | JJ | denotes | null |
T14454 | 28592-28594 | IN | denotes | of |
T14455 | 28595-28599 | NN | denotes | Fog2 |
T14456 | 28600-28609 | VBN | denotes | generated |
T14457 | 28610-28612 | IN | denotes | by |
T14458 | 28613-28617 | NN | denotes | gene |
T14459 | 28618-28627 | NN | denotes | targeting |
T14460 | 28628-28629 | -LRB- | denotes | [ |
T14461 | 28629-28631 | CD | denotes | 16 |
T14462 | 28631-28632 | -RRB- | denotes | ] |
T14463 | 28638-28641 | DT | denotes | the |
T14464 | 28651-28655 | NN | denotes | gift |
T14465 | 28642-28650 | JJ | denotes | generous |
T14466 | 28656-28658 | IN | denotes | of |
T14467 | 28659-28662 | NNP | denotes | Dr. |
T14468 | 28670-28675 | NNP | denotes | Orkin |
T14469 | 28663-28669 | NNP | denotes | Stuart |
T14470 | 28675-28676 | . | denotes | . |
T15313 | 28678-28691 | JJ | denotes | Developmental |
T15314 | 28692-28700 | NN | denotes | analysis |
T15315 | 28701-28703 | IN | denotes | of |
T15316 | 28704-28708 | NNS | denotes | mice |
T15317 | 28708-28709 | . | denotes | . |
T15318 | 28709-28778 | sentence | denotes | Timed pregnancies were set up for collection of E11.5–E17.5 embryos. |
T15319 | 28710-28715 | JJ | denotes | Timed |
T15320 | 28716-28727 | NNS | denotes | pregnancies |
T15321 | 28733-28736 | VBN | denotes | set |
T15322 | 28728-28732 | VBD | denotes | were |
T15323 | 28737-28739 | RP | denotes | up |
T15324 | 28740-28743 | IN | denotes | for |
T15325 | 28744-28754 | NN | denotes | collection |
T15326 | 28755-28757 | IN | denotes | of |
T15327 | 28758-28763 | NN | denotes | E11.5 |
T15328 | 28770-28777 | NNS | denotes | embryos |
T15329 | 28763-28764 | SYM | denotes | – |
T15330 | 28764-28769 | NN | denotes | E17.5 |
T15331 | 28777-28778 | . | denotes | . |
T15332 | 28778-28856 | sentence | denotes | Embryos were fixed, dehydrated, and embedded in paraffin prior to sectioning. |
T15333 | 28779-28786 | NNS | denotes | Embryos |
T15334 | 28792-28797 | VBN | denotes | fixed |
T15335 | 28787-28791 | VBD | denotes | were |
T15336 | 28797-28799 | , | denotes | , |
T15337 | 28799-28809 | VBN | denotes | dehydrated |
T15338 | 28809-28811 | , | denotes | , |
T15339 | 28811-28814 | CC | denotes | and |
T15340 | 28815-28823 | VBN | denotes | embedded |
T15341 | 28824-28826 | IN | denotes | in |
T15342 | 28827-28835 | NN | denotes | paraffin |
T15343 | 28836-28841 | JJ | denotes | prior |
T15344 | 28842-28844 | IN | denotes | to |
T15345 | 28845-28855 | NN | denotes | sectioning |
T15346 | 28855-28856 | . | denotes | . |
T15347 | 28856-28983 | sentence | denotes | In older embryos, a median sternotomy was performed under microscopic guidance, and diaphragm, lungs, and heart were examined. |
T15348 | 28857-28859 | IN | denotes | In |
T15349 | 28899-28908 | VBN | denotes | performed |
T15350 | 28860-28865 | JJR | denotes | older |
T15351 | 28866-28873 | NNS | denotes | embryos |
T15352 | 28873-28875 | , | denotes | , |
T15353 | 28875-28876 | DT | denotes | a |
T15354 | 28884-28894 | NN | denotes | sternotomy |
T15355 | 28877-28883 | JJ | denotes | median |
T15356 | 28895-28898 | VBD | denotes | was |
T15357 | 28909-28914 | IN | denotes | under |
T15358 | 28915-28926 | JJ | denotes | microscopic |
T15359 | 28927-28935 | NN | denotes | guidance |
T15360 | 28935-28937 | , | denotes | , |
T15361 | 28937-28940 | CC | denotes | and |
T15362 | 28941-28950 | NN | denotes | diaphragm |
T15363 | 28974-28982 | VBN | denotes | examined |
T15364 | 28950-28952 | , | denotes | , |
T15365 | 28952-28957 | NNS | denotes | lungs |
T15366 | 28957-28959 | , | denotes | , |
T15367 | 28959-28962 | CC | denotes | and |
T15368 | 28963-28968 | NN | denotes | heart |
T15369 | 28969-28973 | VBD | denotes | were |
T15370 | 28982-28983 | . | denotes | . |
T15371 | 28983-29045 | sentence | denotes | The lungs and tracheobronchial tree were removed and weighed. |
T15372 | 28984-28987 | DT | denotes | The |
T15373 | 28988-28993 | NNS | denotes | lungs |
T15374 | 29025-29032 | VBN | denotes | removed |
T15375 | 28994-28997 | CC | denotes | and |
T15376 | 28998-29014 | JJ | denotes | tracheobronchial |
T15377 | 29015-29019 | NN | denotes | tree |
T15378 | 29020-29024 | VBD | denotes | were |
T15379 | 29033-29036 | CC | denotes | and |
T15380 | 29037-29044 | VBN | denotes | weighed |
T15381 | 29044-29045 | . | denotes | . |
T15382 | 29045-29133 | sentence | denotes | Whole diaphragms were isolated from fixed thoracic tissue from E15.5 and E17.5 embryos. |
T15383 | 29046-29051 | JJ | denotes | Whole |
T15384 | 29052-29062 | NNS | denotes | diaphragms |
T15385 | 29068-29076 | VBN | denotes | isolated |
T15386 | 29063-29067 | VBD | denotes | were |
T15387 | 29077-29081 | IN | denotes | from |
T15388 | 29082-29087 | VBN | denotes | fixed |
T15389 | 29097-29103 | NN | denotes | tissue |
T15390 | 29088-29096 | JJ | denotes | thoracic |
T15391 | 29104-29108 | IN | denotes | from |
T15392 | 29109-29114 | NN | denotes | E15.5 |
T15393 | 29125-29132 | NNS | denotes | embryos |
T15394 | 29115-29118 | CC | denotes | and |
T15395 | 29119-29124 | NN | denotes | E17.5 |
T15396 | 29132-29133 | . | denotes | . |
T15397 | 29133-29572 | sentence | denotes | For lung explant culture, lungs were dissected from fresh embryos at E11.5 and E12.5 and placed on porous 24-mm (0.4-μ) polyester membranes floated in wells containing 2 ml of Dulbecco's modified Eagle's medium, nutrient mixture F-12 (11039–021, Gibco, San Diego, California, United States), supplemented with 10% fetal bovine serum, 0.3 mg/ml L-glutamine, 100 units/ml penicillin, 100 mcg/ml streptomycin, and 0.25 mcg/ml amphotericin B. |
T15398 | 29134-29137 | IN | denotes | For |
T15399 | 29171-29180 | VBN | denotes | dissected |
T15400 | 29138-29142 | NN | denotes | lung |
T15401 | 29151-29158 | NN | denotes | culture |
T15402 | 29143-29150 | NN | denotes | explant |
T15403 | 29158-29160 | , | denotes | , |
T15404 | 29160-29165 | NNS | denotes | lungs |
T15405 | 29166-29170 | VBD | denotes | were |
T15406 | 29181-29185 | IN | denotes | from |
T15407 | 29186-29191 | JJ | denotes | fresh |
T15408 | 29192-29199 | NNS | denotes | embryos |
T15409 | 29200-29202 | IN | denotes | at |
T15410 | 29203-29208 | NN | denotes | E11.5 |
T15411 | 29209-29212 | CC | denotes | and |
T15412 | 29213-29218 | NN | denotes | E12.5 |
T15413 | 29219-29222 | CC | denotes | and |
T15414 | 29223-29229 | VBN | denotes | placed |
T15415 | 29230-29232 | IN | denotes | on |
T15416 | 29233-29239 | JJ | denotes | porous |
T15417 | 29264-29273 | NNS | denotes | membranes |
T15418 | 29240-29242 | CD | denotes | 24 |
T15419 | 29243-29245 | NN | denotes | mm |
T15420 | 29242-29243 | HYPH | denotes | - |
T15421 | 29246-29247 | -LRB- | denotes | ( |
T15422 | 29251-29252 | NN | denotes | μ |
T15423 | 29247-29250 | CD | denotes | 0.4 |
T15424 | 29250-29251 | HYPH | denotes | - |
T15425 | 29252-29253 | -RRB- | denotes | ) |
T15426 | 29254-29263 | NN | denotes | polyester |
T15427 | 29274-29281 | VBN | denotes | floated |
T15428 | 29282-29284 | IN | denotes | in |
T15429 | 29285-29290 | NNS | denotes | wells |
T15430 | 29291-29301 | VBG | denotes | containing |
T15431 | 29302-29303 | CD | denotes | 2 |
T15432 | 29304-29306 | NN | denotes | ml |
T15433 | 29307-29309 | IN | denotes | of |
T15434 | 29310-29318 | NNP | denotes | Dulbecco |
T15435 | 29338-29344 | NN | denotes | medium |
T15436 | 29318-29320 | POS | denotes | 's |
T15437 | 29321-29329 | VBN | denotes | modified |
T15438 | 29330-29335 | NNP | denotes | Eagle |
T15439 | 29335-29337 | POS | denotes | 's |
T15440 | 29344-29346 | , | denotes | , |
T15441 | 29346-29354 | NN | denotes | nutrient |
T15442 | 29355-29362 | NN | denotes | mixture |
T15443 | 29363-29364 | NN | denotes | F |
T15444 | 29364-29365 | HYPH | denotes | - |
T15445 | 29365-29367 | CD | denotes | 12 |
T15446 | 29368-29369 | -LRB- | denotes | ( |
T15447 | 29380-29385 | NNP | denotes | Gibco |
T15448 | 29369-29374 | CD | denotes | 11039 |
T15449 | 29375-29378 | CD | denotes | 021 |
T15450 | 29374-29375 | HYPH | denotes | – |
T15451 | 29378-29380 | , | denotes | , |
T15452 | 29385-29387 | , | denotes | , |
T15453 | 29387-29390 | NNP | denotes | San |
T15454 | 29391-29396 | NNP | denotes | Diego |
T15455 | 29396-29398 | , | denotes | , |
T15456 | 29398-29408 | NNP | denotes | California |
T15457 | 29408-29410 | , | denotes | , |
T15458 | 29410-29416 | NNP | denotes | United |
T15459 | 29417-29423 | NNP | denotes | States |
T15460 | 29423-29424 | -RRB- | denotes | ) |
T15461 | 29424-29426 | , | denotes | , |
T15462 | 29426-29438 | VBN | denotes | supplemented |
T15463 | 29439-29443 | IN | denotes | with |
T15464 | 29444-29446 | CD | denotes | 10 |
T15465 | 29446-29447 | NN | denotes | % |
T15466 | 29461-29466 | NN | denotes | serum |
T15467 | 29448-29453 | JJ | denotes | fetal |
T15468 | 29454-29460 | JJ | denotes | bovine |
T15469 | 29466-29468 | , | denotes | , |
T15470 | 29468-29471 | CD | denotes | 0.3 |
T15471 | 29472-29474 | NN | denotes | mg |
T15472 | 29480-29489 | NN | denotes | glutamine |
T15473 | 29474-29475 | SYM | denotes | / |
T15474 | 29475-29477 | NN | denotes | ml |
T15475 | 29478-29479 | NN | denotes | L |
T15476 | 29479-29480 | HYPH | denotes | - |
T15477 | 29489-29491 | , | denotes | , |
T15478 | 29491-29494 | CD | denotes | 100 |
T15479 | 29495-29500 | NNS | denotes | units |
T15480 | 29504-29514 | NN | denotes | penicillin |
T15481 | 29500-29501 | SYM | denotes | / |
T15482 | 29501-29503 | NN | denotes | ml |
T15483 | 29514-29516 | , | denotes | , |
T15484 | 29516-29519 | CD | denotes | 100 |
T15485 | 29520-29523 | NN | denotes | mcg |
T15486 | 29527-29539 | NN | denotes | streptomycin |
T15487 | 29523-29524 | SYM | denotes | / |
T15488 | 29524-29526 | NN | denotes | ml |
T15489 | 29539-29541 | , | denotes | , |
T15490 | 29541-29544 | CC | denotes | and |
T15491 | 29545-29549 | CD | denotes | 0.25 |
T15492 | 29550-29553 | NN | denotes | mcg |
T15493 | 29570-29571 | NN | denotes | B |
T15494 | 29553-29554 | SYM | denotes | / |
T15495 | 29554-29556 | NN | denotes | ml |
T15496 | 29557-29569 | NN | denotes | amphotericin |
T15497 | 29571-29572 | . | denotes | . |
T15498 | 29572-29642 | sentence | denotes | Lung explants were cultured at 37 °C in 95% air/5% CO2 for up to 5 d. |
T15499 | 29573-29577 | NN | denotes | Lung |
T15500 | 29578-29586 | NNS | denotes | explants |
T15501 | 29592-29600 | VBN | denotes | cultured |
T15502 | 29587-29591 | VBD | denotes | were |
T15503 | 29601-29603 | IN | denotes | at |
T15504 | 29604-29606 | CD | denotes | 37 |
T15505 | 29607-29609 | NN | denotes | °C |
T15506 | 29610-29612 | IN | denotes | in |
T15507 | 29613-29615 | CD | denotes | 95 |
T15508 | 29615-29616 | NN | denotes | % |
T15509 | 29617-29620 | NN | denotes | air |
T15510 | 29620-29621 | HYPH | denotes | / |
T15511 | 29621-29622 | CD | denotes | 5 |
T15512 | 29622-29623 | NN | denotes | % |
T15513 | 29624-29627 | NN | denotes | CO2 |
T15514 | 29628-29631 | IN | denotes | for |
T15515 | 29632-29634 | RB | denotes | up |
T15516 | 29638-29639 | CD | denotes | 5 |
T15517 | 29635-29637 | IN | denotes | to |
T15518 | 29640-29641 | NN | denotes | d |
T15519 | 29641-29642 | . | denotes | . |
T15520 | 29642-29778 | sentence | denotes | They were photographed daily with a dissecting microscope (MZ12.5, Leica, Wetzlar, Germany) equipped with a Leica DC500 digital camera. |
T15521 | 29643-29647 | PRP | denotes | They |
T15522 | 29653-29665 | VBN | denotes | photographed |
T15523 | 29648-29652 | VBD | denotes | were |
T15524 | 29666-29671 | RB | denotes | daily |
T15525 | 29672-29676 | IN | denotes | with |
T15526 | 29677-29678 | DT | denotes | a |
T15527 | 29690-29700 | NN | denotes | microscope |
T15528 | 29679-29689 | VBG | denotes | dissecting |
T15529 | 29701-29702 | -LRB- | denotes | ( |
T15530 | 29702-29708 | NN | denotes | MZ12.5 |
T15531 | 29708-29710 | , | denotes | , |
T15532 | 29710-29715 | NNP | denotes | Leica |
T15533 | 29715-29717 | , | denotes | , |
T15534 | 29717-29724 | NNP | denotes | Wetzlar |
T15535 | 29724-29726 | , | denotes | , |
T15536 | 29726-29733 | NNP | denotes | Germany |
T15537 | 29733-29734 | -RRB- | denotes | ) |
T15538 | 29735-29743 | VBN | denotes | equipped |
T15539 | 29744-29748 | IN | denotes | with |
T15540 | 29749-29750 | DT | denotes | a |
T15541 | 29771-29777 | NN | denotes | camera |
T15542 | 29751-29756 | NNP | denotes | Leica |
T15543 | 29757-29762 | NN | denotes | DC500 |
T15544 | 29763-29770 | JJ | denotes | digital |
T15545 | 29777-29778 | . | denotes | . |
T15546 | 29778-29881 | sentence | denotes | Transgenic mice carrying the lacZ gene driven by the Fog2 promoter have been developed by S. Tevosian. |
T15547 | 29779-29789 | JJ | denotes | Transgenic |
T15548 | 29790-29794 | NNS | denotes | mice |
T15549 | 29856-29865 | VBN | denotes | developed |
T15550 | 29795-29803 | VBG | denotes | carrying |
T15551 | 29804-29807 | DT | denotes | the |
T15552 | 29813-29817 | NN | denotes | gene |
T15553 | 29808-29812 | NN | denotes | lacZ |
T15554 | 29818-29824 | VBN | denotes | driven |
T15555 | 29825-29827 | IN | denotes | by |
T15556 | 29828-29831 | DT | denotes | the |
T15557 | 29837-29845 | NN | denotes | promoter |
T15558 | 29832-29836 | NN | denotes | Fog2 |
T15559 | 29846-29850 | VBP | denotes | have |
T15560 | 29851-29855 | VBN | denotes | been |
T15561 | 29866-29868 | IN | denotes | by |
T15562 | 29869-29871 | NNP | denotes | S. |
T15563 | 29872-29880 | NNP | denotes | Tevosian |
T15564 | 29880-29881 | . | denotes | . |
T15565 | 29881-30081 | sentence | denotes | In these animals, the lacZ gene is incorporated (“knocked-in”) into the Fog2 locus to allow β-galactosidase expression as a fusion protein in frame with the first 235 amino acids of the FOG2 protein. |
T15566 | 29882-29884 | IN | denotes | In |
T15567 | 29917-29929 | VBN | denotes | incorporated |
T15568 | 29885-29890 | DT | denotes | these |
T15569 | 29891-29898 | NNS | denotes | animals |
T15570 | 29898-29900 | , | denotes | , |
T15571 | 29900-29903 | DT | denotes | the |
T15572 | 29909-29913 | NN | denotes | gene |
T15573 | 29904-29908 | NN | denotes | lacZ |
T15574 | 29914-29916 | VBZ | denotes | is |
T15575 | 29930-29931 | -LRB- | denotes | ( |
T15576 | 29932-29939 | VBN | denotes | knocked |
T15577 | 29931-29932 | `` | denotes | “ |
T15578 | 29939-29940 | HYPH | denotes | - |
T15579 | 29940-29942 | RP | denotes | in |
T15580 | 29942-29943 | '' | denotes | ” |
T15581 | 29943-29944 | -RRB- | denotes | ) |
T15582 | 29945-29949 | IN | denotes | into |
T15583 | 29950-29953 | DT | denotes | the |
T15584 | 29959-29964 | NN | denotes | locus |
T15585 | 29954-29958 | NN | denotes | Fog2 |
T15586 | 29965-29967 | TO | denotes | to |
T15587 | 29968-29973 | VB | denotes | allow |
T15588 | 29974-29975 | NN | denotes | β |
T15589 | 29976-29989 | NN | denotes | galactosidase |
T15590 | 29975-29976 | HYPH | denotes | - |
T15591 | 29990-30000 | NN | denotes | expression |
T15592 | 30001-30003 | IN | denotes | as |
T15593 | 30004-30005 | DT | denotes | a |
T15594 | 30013-30020 | NN | denotes | protein |
T15595 | 30006-30012 | NN | denotes | fusion |
T15596 | 30021-30023 | IN | denotes | in |
T15597 | 30024-30029 | NN | denotes | frame |
T15598 | 30030-30034 | IN | denotes | with |
T15599 | 30035-30038 | DT | denotes | the |
T15600 | 30055-30060 | NNS | denotes | acids |
T15601 | 30039-30044 | JJ | denotes | first |
T15602 | 30045-30048 | CD | denotes | 235 |
T15603 | 30049-30054 | NN | denotes | amino |
T15604 | 30061-30063 | IN | denotes | of |
T15605 | 30064-30067 | DT | denotes | the |
T15606 | 30073-30080 | NN | denotes | protein |
T15607 | 30068-30072 | NN | denotes | FOG2 |
T15608 | 30080-30081 | . | denotes | . |
T15609 | 30081-30140 | sentence | denotes | The Fog2-lacZ module is followed by an ires-eGFP cassette. |
T15610 | 30082-30085 | DT | denotes | The |
T15611 | 30096-30102 | NN | denotes | module |
T15612 | 30086-30090 | NN | denotes | Fog2 |
T15613 | 30091-30095 | NN | denotes | lacZ |
T15614 | 30090-30091 | HYPH | denotes | - |
T15615 | 30106-30114 | VBN | denotes | followed |
T15616 | 30103-30105 | VBZ | denotes | is |
T15617 | 30115-30117 | IN | denotes | by |
T15618 | 30118-30120 | DT | denotes | an |
T15619 | 30131-30139 | NN | denotes | cassette |
T15620 | 30121-30125 | NN | denotes | ires |
T15621 | 30126-30130 | NN | denotes | eGFP |
T15622 | 30125-30126 | HYPH | denotes | - |
T15623 | 30139-30140 | . | denotes | . |
T15624 | 30140-30181 | sentence | denotes | This creates a null allele of Fog2 gene. |
T15625 | 30141-30145 | DT | denotes | This |
T15626 | 30146-30153 | VBZ | denotes | creates |
T15627 | 30154-30155 | DT | denotes | a |
T15628 | 30161-30167 | NN | denotes | allele |
T15629 | 30156-30160 | JJ | denotes | null |
T15630 | 30168-30170 | IN | denotes | of |
T15631 | 30171-30175 | NN | denotes | Fog2 |
T15632 | 30176-30180 | NN | denotes | gene |
T15633 | 30180-30181 | . | denotes | . |
T15634 | 30181-30277 | sentence | denotes | The Fog2-LacZ-eGFP construct was linearized with KspI and electroporated into the CJ7 ES cells. |
T15635 | 30182-30185 | DT | denotes | The |
T15636 | 30201-30210 | NN | denotes | construct |
T15637 | 30186-30190 | NN | denotes | Fog2 |
T15638 | 30196-30200 | NN | denotes | eGFP |
T15639 | 30190-30191 | HYPH | denotes | - |
T15640 | 30191-30195 | NN | denotes | LacZ |
T15641 | 30195-30196 | HYPH | denotes | - |
T15642 | 30215-30225 | VBN | denotes | linearized |
T15643 | 30211-30214 | VBD | denotes | was |
T15644 | 30226-30230 | IN | denotes | with |
T15645 | 30231-30235 | NN | denotes | KspI |
T15646 | 30236-30239 | CC | denotes | and |
T15647 | 30240-30254 | VBN | denotes | electroporated |
T15648 | 30255-30259 | IN | denotes | into |
T15649 | 30260-30263 | DT | denotes | the |
T15650 | 30271-30276 | NNS | denotes | cells |
T15651 | 30264-30267 | NN | denotes | CJ7 |
T15652 | 30268-30270 | NN | denotes | ES |
T15653 | 30276-30277 | . | denotes | . |
T15654 | 30277-30389 | sentence | denotes | The correctly targeted clone was selected by the Southern blot analysis and injected into C57BL/6J blastocysts. |
T15655 | 30278-30281 | DT | denotes | The |
T15656 | 30301-30306 | NN | denotes | clone |
T15657 | 30282-30291 | RB | denotes | correctly |
T15658 | 30292-30300 | VBN | denotes | targeted |
T15659 | 30311-30319 | VBN | denotes | selected |
T15660 | 30307-30310 | VBD | denotes | was |
T15661 | 30320-30322 | IN | denotes | by |
T15662 | 30323-30326 | DT | denotes | the |
T15663 | 30341-30349 | NN | denotes | analysis |
T15664 | 30327-30335 | NNP | denotes | Southern |
T15665 | 30336-30340 | NN | denotes | blot |
T15666 | 30350-30353 | CC | denotes | and |
T15667 | 30354-30362 | VBN | denotes | injected |
T15668 | 30363-30367 | IN | denotes | into |
T15669 | 30368-30373 | NN | denotes | C57BL |
T15670 | 30374-30376 | NN | denotes | 6J |
T15671 | 30373-30374 | HYPH | denotes | / |
T15672 | 30377-30388 | NNS | denotes | blastocysts |
T15673 | 30388-30389 | . | denotes | . |
T15674 | 30389-30466 | sentence | denotes | Fog2-lacZ-eGFP animals were maintained on the mixed C57BL/6J/129 background. |
T15675 | 30390-30394 | NN | denotes | Fog2 |
T15676 | 30400-30404 | NN | denotes | eGFP |
T15677 | 30394-30395 | HYPH | denotes | - |
T15678 | 30395-30399 | NN | denotes | lacZ |
T15679 | 30399-30400 | HYPH | denotes | - |
T15680 | 30405-30412 | NNS | denotes | animals |
T15681 | 30418-30428 | VBN | denotes | maintained |
T15682 | 30413-30417 | VBD | denotes | were |
T15683 | 30429-30431 | IN | denotes | on |
T15684 | 30432-30435 | DT | denotes | the |
T15685 | 30455-30465 | NN | denotes | background |
T15686 | 30436-30441 | JJ | denotes | mixed |
T15687 | 30442-30447 | NN | denotes | C57BL |
T15688 | 30448-30450 | NN | denotes | 6J |
T15689 | 30447-30448 | HYPH | denotes | / |
T15690 | 30450-30451 | HYPH | denotes | / |
T15691 | 30451-30454 | CD | denotes | 129 |
T15692 | 30465-30466 | . | denotes | . |
T15693 | 30466-30609 | sentence | denotes | lacZ Expression in whole dissected embryonic lungs was analyzed by staining for β-galactosidase activity with X-gal after fixation for 30 min. |
T15694 | 30467-30471 | NN | denotes | lacZ |
T15695 | 30472-30482 | NN | denotes | Expression |
T15696 | 30522-30530 | VBN | denotes | analyzed |
T15697 | 30483-30485 | IN | denotes | in |
T15698 | 30486-30491 | JJ | denotes | whole |
T15699 | 30512-30517 | NNS | denotes | lungs |
T15700 | 30492-30501 | VBN | denotes | dissected |
T15701 | 30502-30511 | JJ | denotes | embryonic |
T15702 | 30518-30521 | VBD | denotes | was |
T15703 | 30531-30533 | IN | denotes | by |
T15704 | 30534-30542 | VBG | denotes | staining |
T15705 | 30543-30546 | IN | denotes | for |
T15706 | 30547-30548 | NN | denotes | β |
T15707 | 30549-30562 | NN | denotes | galactosidase |
T15708 | 30548-30549 | HYPH | denotes | - |
T15709 | 30563-30571 | NN | denotes | activity |
T15710 | 30572-30576 | IN | denotes | with |
T15711 | 30577-30578 | NN | denotes | X |
T15712 | 30579-30582 | NN | denotes | gal |
T15713 | 30578-30579 | HYPH | denotes | - |
T15714 | 30583-30588 | IN | denotes | after |
T15715 | 30589-30597 | NN | denotes | fixation |
T15716 | 30598-30601 | IN | denotes | for |
T15717 | 30602-30604 | CD | denotes | 30 |
T15718 | 30605-30608 | NN | denotes | min |
T15719 | 30608-30609 | . | denotes | . |
T16000 | 30611-30613 | NN | denotes | RT |
T16001 | 30614-30617 | NN | denotes | PCR |
T16002 | 30613-30614 | HYPH | denotes | - |
T16003 | 30618-30621 | CC | denotes | and |
T16004 | 30622-30630 | NN | denotes | sequence |
T16005 | 30631-30639 | NN | denotes | analysis |
T16006 | 30640-30642 | IN | denotes | in |
T16007 | 30643-30646 | DT | denotes | the |
T16008 | 30647-30652 | NN | denotes | mouse |
T16009 | 30652-30653 | . | denotes | . |
T16010 | 30653-30726 | sentence | denotes | RNA was extracted by standard techniques from thoracic embryonic tissue. |
T16011 | 30654-30657 | NN | denotes | RNA |
T16012 | 30662-30671 | VBN | denotes | extracted |
T16013 | 30658-30661 | VBD | denotes | was |
T16014 | 30672-30674 | IN | denotes | by |
T16015 | 30675-30683 | JJ | denotes | standard |
T16016 | 30684-30694 | NNS | denotes | techniques |
T16017 | 30695-30699 | IN | denotes | from |
T16018 | 30700-30708 | JJ | denotes | thoracic |
T16019 | 30719-30725 | NN | denotes | tissue |
T16020 | 30709-30718 | JJ | denotes | embryonic |
T16021 | 30725-30726 | . | denotes | . |
T16022 | 30726-30802 | sentence | denotes | RT-PCR was performed using six primer sets designed to cover the Fog2 gene. |
T16023 | 30727-30729 | NN | denotes | RT |
T16024 | 30730-30733 | NN | denotes | PCR |
T16025 | 30729-30730 | HYPH | denotes | - |
T16026 | 30738-30747 | VBN | denotes | performed |
T16027 | 30734-30737 | VBD | denotes | was |
T16028 | 30748-30753 | VBG | denotes | using |
T16029 | 30754-30757 | CD | denotes | six |
T16030 | 30765-30769 | NNS | denotes | sets |
T16031 | 30758-30764 | NN | denotes | primer |
T16032 | 30770-30778 | VBN | denotes | designed |
T16033 | 30779-30781 | TO | denotes | to |
T16034 | 30782-30787 | VB | denotes | cover |
T16035 | 30788-30791 | DT | denotes | the |
T16036 | 30797-30801 | NN | denotes | gene |
T16037 | 30792-30796 | NN | denotes | Fog2 |
T16038 | 30801-30802 | . | denotes | . |
T16039 | 30802-31001 | sentence | denotes | RT-PCR was repeated with radiolabeled primers to amplify an abnormally spliced region of the gene (Table S1), and the product was run on a denaturing sequencing gel according to standard techniques. |
T16040 | 30803-30805 | NN | denotes | RT |
T16041 | 30806-30809 | NN | denotes | PCR |
T16042 | 30805-30806 | HYPH | denotes | - |
T16043 | 30814-30822 | VBN | denotes | repeated |
T16044 | 30810-30813 | VBD | denotes | was |
T16045 | 30823-30827 | IN | denotes | with |
T16046 | 30828-30840 | VBN | denotes | radiolabeled |
T16047 | 30841-30848 | NNS | denotes | primers |
T16048 | 30849-30851 | TO | denotes | to |
T16049 | 30852-30859 | VB | denotes | amplify |
T16050 | 30860-30862 | DT | denotes | an |
T16051 | 30882-30888 | NN | denotes | region |
T16052 | 30863-30873 | RB | denotes | abnormally |
T16053 | 30874-30881 | VBN | denotes | spliced |
T16054 | 30889-30891 | IN | denotes | of |
T16055 | 30892-30895 | DT | denotes | the |
T16056 | 30896-30900 | NN | denotes | gene |
T16057 | 30901-30902 | -LRB- | denotes | ( |
T16058 | 30908-30910 | NN | denotes | S1 |
T16059 | 30902-30907 | NN | denotes | Table |
T16060 | 30910-30911 | -RRB- | denotes | ) |
T16061 | 30911-30913 | , | denotes | , |
T16062 | 30913-30916 | CC | denotes | and |
T16063 | 30917-30920 | DT | denotes | the |
T16064 | 30921-30928 | NN | denotes | product |
T16065 | 30933-30936 | VBN | denotes | run |
T16066 | 30929-30932 | VBD | denotes | was |
T16067 | 30937-30939 | IN | denotes | on |
T16068 | 30940-30941 | DT | denotes | a |
T16069 | 30964-30967 | NN | denotes | gel |
T16070 | 30942-30952 | VBG | denotes | denaturing |
T16071 | 30953-30963 | NN | denotes | sequencing |
T16072 | 30968-30977 | VBG | denotes | according |
T16073 | 30978-30980 | IN | denotes | to |
T16074 | 30981-30989 | JJ | denotes | standard |
T16075 | 30990-31000 | NNS | denotes | techniques |
T16076 | 31000-31001 | . | denotes | . |
T16077 | 31001-31169 | sentence | denotes | The RT-PCR product was cloned into pCR2.1 vector using TOPO TA Cloning Kit (Invitrogen, Carlsbad, California, United States) and sequenced using gene-specific primers. |
T16078 | 31002-31005 | DT | denotes | The |
T16079 | 31013-31020 | NN | denotes | product |
T16080 | 31006-31008 | NN | denotes | RT |
T16081 | 31009-31012 | NN | denotes | PCR |
T16082 | 31008-31009 | HYPH | denotes | - |
T16083 | 31025-31031 | VBN | denotes | cloned |
T16084 | 31021-31024 | VBD | denotes | was |
T16085 | 31032-31036 | IN | denotes | into |
T16086 | 31037-31043 | NN | denotes | pCR2.1 |
T16087 | 31044-31050 | NN | denotes | vector |
T16088 | 31051-31056 | VBG | denotes | using |
T16089 | 31057-31061 | NN | denotes | TOPO |
T16090 | 31073-31076 | NNP | denotes | Kit |
T16091 | 31062-31064 | NN | denotes | TA |
T16092 | 31065-31072 | NNP | denotes | Cloning |
T16093 | 31077-31078 | -LRB- | denotes | ( |
T16094 | 31078-31088 | NNP | denotes | Invitrogen |
T16095 | 31088-31090 | , | denotes | , |
T16096 | 31090-31098 | NNP | denotes | Carlsbad |
T16097 | 31098-31100 | , | denotes | , |
T16098 | 31100-31110 | NNP | denotes | California |
T16099 | 31110-31112 | , | denotes | , |
T16100 | 31112-31118 | NNP | denotes | United |
T16101 | 31119-31125 | NNP | denotes | States |
T16102 | 31125-31126 | -RRB- | denotes | ) |
T16103 | 31127-31130 | CC | denotes | and |
T16104 | 31131-31140 | VBN | denotes | sequenced |
T16105 | 31141-31146 | VBG | denotes | using |
T16106 | 31147-31151 | NN | denotes | gene |
T16107 | 31152-31160 | JJ | denotes | specific |
T16108 | 31151-31152 | HYPH | denotes | - |
T16109 | 31161-31168 | NNS | denotes | primers |
T16110 | 31168-31169 | . | denotes | . |
T16111 | 31169-31267 | sentence | denotes | Sequence analysis was done using Sequencher 4.1 (Gene Codes, Ann Arbor, Michigan, United States). |
T16112 | 31170-31178 | NN | denotes | Sequence |
T16113 | 31179-31187 | NN | denotes | analysis |
T16114 | 31192-31196 | VBN | denotes | done |
T16115 | 31188-31191 | VBD | denotes | was |
T16116 | 31197-31202 | VBG | denotes | using |
T16117 | 31203-31213 | NNP | denotes | Sequencher |
T16118 | 31214-31217 | CD | denotes | 4.1 |
T16119 | 31218-31219 | -LRB- | denotes | ( |
T16120 | 31224-31229 | NNPS | denotes | Codes |
T16121 | 31219-31223 | NNP | denotes | Gene |
T16122 | 31229-31231 | , | denotes | , |
T16123 | 31231-31234 | NNP | denotes | Ann |
T16124 | 31235-31240 | NNP | denotes | Arbor |
T16125 | 31240-31242 | , | denotes | , |
T16126 | 31242-31250 | NNP | denotes | Michigan |
T16127 | 31250-31252 | , | denotes | , |
T16128 | 31252-31258 | NNP | denotes | United |
T16129 | 31259-31265 | NNP | denotes | States |
T16130 | 31265-31266 | -RRB- | denotes | ) |
T16131 | 31266-31267 | . | denotes | . |
T16289 | 31269-31271 | FW | denotes | In |
T16290 | 31272-31276 | FW | denotes | situ |
T16291 | 31277-31290 | NN | denotes | hybridization |
T16292 | 31290-31291 | . | denotes | . |
T16293 | 31291-31425 | sentence | denotes | After dehydration and embedding in paraffin wax, 10-μ sections were subjected to radioactive in situ hybridization as described [53]. |
T16294 | 31292-31297 | IN | denotes | After |
T16295 | 31360-31369 | VBN | denotes | subjected |
T16296 | 31298-31309 | NN | denotes | dehydration |
T16297 | 31310-31313 | CC | denotes | and |
T16298 | 31314-31323 | NN | denotes | embedding |
T16299 | 31324-31326 | IN | denotes | in |
T16300 | 31327-31335 | NN | denotes | paraffin |
T16301 | 31336-31339 | NN | denotes | wax |
T16302 | 31339-31341 | , | denotes | , |
T16303 | 31341-31343 | CD | denotes | 10 |
T16304 | 31344-31345 | NN | denotes | μ |
T16305 | 31343-31344 | HYPH | denotes | - |
T16306 | 31346-31354 | NNS | denotes | sections |
T16307 | 31355-31359 | VBD | denotes | were |
T16308 | 31370-31372 | IN | denotes | to |
T16309 | 31373-31384 | JJ | denotes | radioactive |
T16310 | 31393-31406 | NN | denotes | hybridization |
T16311 | 31385-31387 | FW | denotes | in |
T16312 | 31388-31392 | FW | denotes | situ |
T16313 | 31407-31409 | IN | denotes | as |
T16314 | 31410-31419 | VBN | denotes | described |
T16315 | 31420-31421 | -LRB- | denotes | [ |
T16316 | 31421-31423 | CD | denotes | 53 |
T16317 | 31423-31424 | -RRB- | denotes | ] |
T16318 | 31424-31425 | . | denotes | . |
T16319 | 31425-31555 | sentence | denotes | Probes labeled with 35S were prepared by run-off transcription of linearized plasmid templates and hybridized to tissue sections. |
T16320 | 31426-31432 | NNS | denotes | Probes |
T16321 | 31455-31463 | VBN | denotes | prepared |
T16322 | 31433-31440 | VBN | denotes | labeled |
T16323 | 31441-31445 | IN | denotes | with |
T16324 | 31446-31449 | NN | denotes | 35S |
T16325 | 31450-31454 | VBD | denotes | were |
T16326 | 31464-31466 | IN | denotes | by |
T16327 | 31467-31470 | VB | denotes | run |
T16328 | 31475-31488 | NN | denotes | transcription |
T16329 | 31470-31471 | HYPH | denotes | - |
T16330 | 31471-31474 | RP | denotes | off |
T16331 | 31489-31491 | IN | denotes | of |
T16332 | 31492-31502 | VBN | denotes | linearized |
T16333 | 31511-31520 | NNS | denotes | templates |
T16334 | 31503-31510 | NN | denotes | plasmid |
T16335 | 31521-31524 | CC | denotes | and |
T16336 | 31525-31535 | VBN | denotes | hybridized |
T16337 | 31536-31538 | IN | denotes | to |
T16338 | 31539-31545 | NN | denotes | tissue |
T16339 | 31546-31554 | NNS | denotes | sections |
T16340 | 31554-31555 | . | denotes | . |
T16341 | 31555-31668 | sentence | denotes | Nuclei were counterstained with Hoescht 33258, and signal was imaged using fluorescent and darkfield microscopy. |
T16342 | 31556-31562 | NNS | denotes | Nuclei |
T16343 | 31568-31582 | VBN | denotes | counterstained |
T16344 | 31563-31567 | VBD | denotes | were |
T16345 | 31583-31587 | IN | denotes | with |
T16346 | 31588-31595 | NNP | denotes | Hoescht |
T16347 | 31596-31601 | CD | denotes | 33258 |
T16348 | 31601-31603 | , | denotes | , |
T16349 | 31603-31606 | CC | denotes | and |
T16350 | 31607-31613 | NN | denotes | signal |
T16351 | 31618-31624 | VBN | denotes | imaged |
T16352 | 31614-31617 | VBD | denotes | was |
T16353 | 31625-31630 | VBG | denotes | using |
T16354 | 31631-31642 | JJ | denotes | fluorescent |
T16355 | 31657-31667 | NN | denotes | microscopy |
T16356 | 31643-31646 | CC | denotes | and |
T16357 | 31647-31656 | NN | denotes | darkfield |
T16358 | 31667-31668 | . | denotes | . |
T16688 | 31670-31675 | JJ | denotes | Human |
T16689 | 31680-31690 | NN | denotes | extraction |
T16690 | 31676-31679 | NN | denotes | DNA |
T16691 | 31691-31694 | CC | denotes | and |
T16692 | 31695-31703 | NN | denotes | sequence |
T16693 | 31704-31712 | NN | denotes | analysis |
T16694 | 31712-31713 | . | denotes | . |
T16695 | 31713-31840 | sentence | denotes | DNA was isolated from paraffin blocks by phenol-chloroform extraction [54,55], and from frozen tissues by standard techniques. |
T16696 | 31714-31717 | NN | denotes | DNA |
T16697 | 31722-31730 | VBN | denotes | isolated |
T16698 | 31718-31721 | VBD | denotes | was |
T16699 | 31731-31735 | IN | denotes | from |
T16700 | 31736-31744 | NN | denotes | paraffin |
T16701 | 31745-31751 | NNS | denotes | blocks |
T16702 | 31752-31754 | IN | denotes | by |
T16703 | 31755-31761 | NN | denotes | phenol |
T16704 | 31762-31772 | NN | denotes | chloroform |
T16705 | 31761-31762 | HYPH | denotes | - |
T16706 | 31773-31783 | NN | denotes | extraction |
T16707 | 31784-31785 | -LRB- | denotes | [ |
T16708 | 31788-31790 | CD | denotes | 55 |
T16709 | 31785-31787 | CD | denotes | 54 |
T16710 | 31787-31788 | , | denotes | , |
T16711 | 31790-31791 | -RRB- | denotes | ] |
T16712 | 31791-31793 | , | denotes | , |
T16713 | 31793-31796 | CC | denotes | and |
T16714 | 31797-31801 | IN | denotes | from |
T16715 | 31802-31808 | VBN | denotes | frozen |
T16716 | 31809-31816 | NNS | denotes | tissues |
T16717 | 31817-31819 | IN | denotes | by |
T16718 | 31820-31828 | JJ | denotes | standard |
T16719 | 31829-31839 | NNS | denotes | techniques |
T16720 | 31839-31840 | . | denotes | . |
T16721 | 31840-31948 | sentence | denotes | Primers were designed to amplify FOG2 coding exons plus 50 bp of flanking upstream and downstream sequence. |
T16722 | 31841-31848 | NNS | denotes | Primers |
T16723 | 31854-31862 | VBN | denotes | designed |
T16724 | 31849-31853 | VBD | denotes | were |
T16725 | 31863-31865 | TO | denotes | to |
T16726 | 31866-31873 | VB | denotes | amplify |
T16727 | 31874-31878 | NN | denotes | FOG2 |
T16728 | 31886-31891 | NNS | denotes | exons |
T16729 | 31879-31885 | NN | denotes | coding |
T16730 | 31892-31896 | CC | denotes | plus |
T16731 | 31897-31899 | CD | denotes | 50 |
T16732 | 31900-31902 | NN | denotes | bp |
T16733 | 31903-31905 | IN | denotes | of |
T16734 | 31906-31914 | VBG | denotes | flanking |
T16735 | 31939-31947 | NN | denotes | sequence |
T16736 | 31915-31923 | JJ | denotes | upstream |
T16737 | 31924-31927 | CC | denotes | and |
T16738 | 31928-31938 | JJ | denotes | downstream |
T16739 | 31947-31948 | . | denotes | . |
T16740 | 31948-32017 | sentence | denotes | PCR amplification and sequencing were performed by standard methods. |
T16741 | 31949-31952 | NN | denotes | PCR |
T16742 | 31953-31966 | NN | denotes | amplification |
T16743 | 31987-31996 | VBN | denotes | performed |
T16744 | 31967-31970 | CC | denotes | and |
T16745 | 31971-31981 | NN | denotes | sequencing |
T16746 | 31982-31986 | VBD | denotes | were |
T16747 | 31997-31999 | IN | denotes | by |
T16748 | 32000-32008 | JJ | denotes | standard |
T16749 | 32009-32016 | NNS | denotes | methods |
T16750 | 32016-32017 | . | denotes | . |
T16751 | 32017-32063 | sentence | denotes | Primer sequences used are listed in Table S2. |
T16752 | 32018-32024 | NN | denotes | Primer |
T16753 | 32025-32034 | NNS | denotes | sequences |
T16754 | 32044-32050 | VBN | denotes | listed |
T16755 | 32035-32039 | VBN | denotes | used |
T16756 | 32040-32043 | VBP | denotes | are |
T16757 | 32051-32053 | IN | denotes | in |
T16758 | 32054-32059 | NN | denotes | Table |
T16759 | 32060-32062 | NN | denotes | S2 |
T16760 | 32062-32063 | . | denotes | . |
T16761 | 32063-32124 | sentence | denotes | Sequence analysis was done with Sequencher 4.1 (Gene Codes). |
T16762 | 32064-32072 | NN | denotes | Sequence |
T16763 | 32073-32081 | NN | denotes | analysis |
T16764 | 32086-32090 | VBN | denotes | done |
T16765 | 32082-32085 | VBD | denotes | was |
T16766 | 32091-32095 | IN | denotes | with |
T16767 | 32096-32106 | NNP | denotes | Sequencher |
T16768 | 32107-32110 | CD | denotes | 4.1 |
T16769 | 32111-32112 | -LRB- | denotes | ( |
T16770 | 32117-32122 | NNPS | denotes | Codes |
T16771 | 32112-32116 | NNP | denotes | Gene |
T16772 | 32122-32123 | -RRB- | denotes | ) |
T16773 | 32123-32124 | . | denotes | . |
T16774 | 32124-32208 | sentence | denotes | DNA from the parents of one autopsy patient was extracted from fresh blood samples. |
T16775 | 32125-32128 | NN | denotes | DNA |
T16776 | 32173-32182 | VBN | denotes | extracted |
T16777 | 32129-32133 | IN | denotes | from |
T16778 | 32134-32137 | DT | denotes | the |
T16779 | 32138-32145 | NNS | denotes | parents |
T16780 | 32146-32148 | IN | denotes | of |
T16781 | 32149-32152 | CD | denotes | one |
T16782 | 32161-32168 | NN | denotes | patient |
T16783 | 32153-32160 | NN | denotes | autopsy |
T16784 | 32169-32172 | VBD | denotes | was |
T16785 | 32183-32187 | IN | denotes | from |
T16786 | 32188-32193 | JJ | denotes | fresh |
T16787 | 32200-32207 | NNS | denotes | samples |
T16788 | 32194-32199 | NN | denotes | blood |
T16789 | 32207-32208 | . | denotes | . |
T16790 | 32208-32338 | sentence | denotes | A second set of blood samples was sent to an outside CLIA-certified laboratory for DNA extraction, PCR, sequencing, and analysis. |
T16791 | 32209-32210 | DT | denotes | A |
T16792 | 32218-32221 | NN | denotes | set |
T16793 | 32211-32217 | JJ | denotes | second |
T16794 | 32243-32247 | VBN | denotes | sent |
T16795 | 32222-32224 | IN | denotes | of |
T16796 | 32225-32230 | NN | denotes | blood |
T16797 | 32231-32238 | NNS | denotes | samples |
T16798 | 32239-32242 | VBD | denotes | was |
T16799 | 32248-32250 | IN | denotes | to |
T16800 | 32251-32253 | DT | denotes | an |
T16801 | 32277-32287 | NN | denotes | laboratory |
T16802 | 32254-32261 | JJ | denotes | outside |
T16803 | 32262-32266 | NN | denotes | CLIA |
T16804 | 32267-32276 | VBN | denotes | certified |
T16805 | 32266-32267 | HYPH | denotes | - |
T16806 | 32288-32291 | IN | denotes | for |
T16807 | 32292-32295 | NN | denotes | DNA |
T16808 | 32296-32306 | NN | denotes | extraction |
T16809 | 32306-32308 | , | denotes | , |
T16810 | 32308-32311 | NN | denotes | PCR |
T16811 | 32311-32313 | , | denotes | , |
T16812 | 32313-32323 | NN | denotes | sequencing |
T16813 | 32323-32325 | , | denotes | , |
T16814 | 32325-32328 | CC | denotes | and |
T16815 | 32329-32337 | NN | denotes | analysis |
T16816 | 32337-32338 | . | denotes | . |
T16817 | 32338-32431 | sentence | denotes | Paternity testing was performed by the outside laboratory using a standard panel of markers. |
T16818 | 32339-32348 | NN | denotes | Paternity |
T16819 | 32349-32356 | NN | denotes | testing |
T16820 | 32361-32370 | VBN | denotes | performed |
T16821 | 32357-32360 | VBD | denotes | was |
T16822 | 32371-32373 | IN | denotes | by |
T16823 | 32374-32377 | DT | denotes | the |
T16824 | 32386-32396 | NN | denotes | laboratory |
T16825 | 32378-32385 | JJ | denotes | outside |
T16826 | 32397-32402 | VBG | denotes | using |
T16827 | 32403-32404 | DT | denotes | a |
T16828 | 32414-32419 | NN | denotes | panel |
T16829 | 32405-32413 | JJ | denotes | standard |
T16830 | 32420-32422 | IN | denotes | of |
T16831 | 32423-32430 | NNS | denotes | markers |
T16832 | 32430-32431 | . | denotes | . |
T16833 | 32431-32579 | sentence | denotes | SNP genotyping was done using Harvard Partners Center for Genetics and Genomics genotyping core facility (Cambridge, Massachusetts, United States). |
T16834 | 32432-32435 | NN | denotes | SNP |
T16835 | 32436-32446 | NN | denotes | genotyping |
T16836 | 32451-32455 | VBN | denotes | done |
T16837 | 32447-32450 | VBD | denotes | was |
T16838 | 32456-32461 | VBG | denotes | using |
T16839 | 32462-32469 | NNP | denotes | Harvard |
T16840 | 32479-32485 | NNP | denotes | Center |
T16841 | 32470-32478 | NNPS | denotes | Partners |
T16842 | 32528-32536 | NN | denotes | facility |
T16843 | 32486-32489 | IN | denotes | for |
T16844 | 32490-32498 | NNP | denotes | Genetics |
T16845 | 32499-32502 | CC | denotes | and |
T16846 | 32503-32511 | NNP | denotes | Genomics |
T16847 | 32512-32522 | NN | denotes | genotyping |
T16848 | 32523-32527 | NN | denotes | core |
T16849 | 32537-32538 | -LRB- | denotes | ( |
T16850 | 32538-32547 | NNP | denotes | Cambridge |
T16851 | 32547-32549 | , | denotes | , |
T16852 | 32549-32562 | NNP | denotes | Massachusetts |
T16853 | 32562-32564 | , | denotes | , |
T16854 | 32564-32570 | NNP | denotes | United |
T16855 | 32571-32577 | NNP | denotes | States |
T16856 | 32577-32578 | -RRB- | denotes | ) |
T16857 | 32578-32579 | . | denotes | . |
T1018 | 212-215 | VBP | denotes | are |
R3 | T1001 | T1000 | auxpass | Is,Required |
R4 | T1002 | T1000 | prep | for,Required |
R5 | T1003 | T1004 | amod | Normal,Development |
R6 | T1004 | T1002 | pobj | Development,for |
R7 | T1005 | T1004 | nmod | Diaphragm,Development |
R8 | T1006 | T1005 | cc | and,Diaphragm |
R9 | T1007 | T1005 | conj | Lung,Diaphragm |
R10 | T1008 | T1000 | prep | in,Required |
R11 | T1009 | T1008 | pobj | Mice,in |
R12 | T1010 | T1009 | cc | and,Mice |
R13 | T1011 | T1009 | conj | Humans,Mice |
R14 | T1015 | T1016 | amod | Congenital,hernia |
R16 | T1017 | T1016 | amod | diaphragmatic,hernia |
R17 | T1019 | T1016 | cc | and,hernia |
R18 | T1020 | T1021 | amod | other,defects |
R19 | T1021 | T1016 | conj | defects,hernia |
R20 | T1022 | T1021 | amod | congenital,defects |
R21 | T1023 | T1021 | amod | diaphragmatic,defects |
R34 | T1037 | T1024 | nsubj | basis,is |
R35 | T1038 | T1037 | amod | molecular,basis |
R38 | T1041 | T1039 | pobj | anomalies,of |
R39 | T1042 | T1041 | amod | developmental,anomalies |
R54 | T1059 | T1057 | pobj | ethyl,with |
R55 | T1060 | T1059 | punct | -,ethyl |
R58 | T1063 | T1059 | appos | nitrosourea,ethyl |
R59 | T1064 | T1063 | punct | -,nitrosourea |
R70 | T1075 | T1072 | conj | development,hypoplasia |
R71 | T1076 | T1075 | amod | diaphragmatic,development |
R79 | T1086 | T1084 | pobj | interval,within |
R80 | T1087 | T1086 | amod | recombinant,interval |
R83 | T1090 | T1088 | dobj | mutation,carrying |
R84 | T1091 | T1092 | compound | N,ethyl |
R86 | T1093 | T1092 | punct | -,ethyl |
R87 | T1094 | T1090 | amod | induced,mutation |
R88 | T1095 | T1092 | punct | -,ethyl |
R89 | T1096 | T1097 | compound | N,nitrosourea |
R90 | T1097 | T1092 | appos | nitrosourea,ethyl |
R91 | T1098 | T1097 | punct | -,nitrosourea |
R92 | T1099 | T1094 | punct | -,induced |
R97 | T1104 | T1080 | conj | identified,maps |
R98 | T1105 | T1103 | prep | of,sequencing |
R99 | T1106 | T1105 | pobj | Fog2,of |
R104 | T1111 | T1109 | pobj | site,in |
R105 | T1112 | T1111 | compound | splice,site |
R106 | T1113 | T1111 | compound | donor,site |
R110 | T1117 | T1115 | dobj | transcript,generates |
R111 | T1118 | T1117 | amod | abnormal,transcript |
R114 | T1121 | T1119 | dobj | protein,encoding |
R115 | T1122 | T1121 | amod | truncated,protein |
R118 | T1126 | T1128 | nsubjpass | cases,evaluated |
R119 | T1127 | T1126 | compound | autopsy,cases |
R135 | T1146 | T1144 | dobj | mutation,revealed |
R136 | T1147 | T1148 | advmod | de,novo |
R137 | T1148 | T1146 | amod | novo,mutation |
R141 | T1152 | T1150 | pobj | codon,in |
R142 | T1153 | T1152 | amod | premature,codon |
R143 | T1154 | T1152 | compound | stop,codon |
R151 | T1162 | T1160 | pobj | day,on |
R152 | T1163 | T1162 | amod | first,day |
R158 | T1169 | T1167 | pobj | hypoplasia,to |
R159 | T1170 | T1169 | amod | bilateral,hypoplasia |
R160 | T1171 | T1169 | amod | pulmonary,hypoplasia |
R163 | T1174 | T1169 | conj | diaphragm,hypoplasia |
R164 | T1175 | T1176 | advmod | abnormally,muscularized |
R165 | T1176 | T1174 | amod | muscularized,diaphragm |
R169 | T1182 | T1179 | dobj | approach,Using |
R170 | T1183 | T1184 | npadvmod | phenotype,driven |
R172 | T1185 | T1184 | punct | -,driven |
R177 | T1190 | T1180 | ccomp | required,established |
R178 | T1191 | T1190 | nsubjpass | Fog2,required |
R179 | T1192 | T1190 | auxpass | is,required |
R182 | T1195 | T1193 | pobj | development,for |
R183 | T1196 | T1195 | nmod | diaphragm,development |
R184 | T1197 | T1196 | cc | and,diaphragm |
R185 | T1198 | T1196 | conj | lung,diaphragm |
R190 | T1203 | T1201 | relcl | appreciated,role |
R191 | T1204 | T1203 | aux | has,appreciated |
R192 | T1205 | T1203 | neg | not,appreciated |
R193 | T1206 | T1203 | auxpass | been,appreciated |
R194 | T1207 | T1203 | advmod | previously,appreciated |
R198 | T1213 | T1211 | attr | gene,is |
R199 | T1214 | T1213 | amod | first,gene |
R206 | T1221 | T1219 | pobj | defects,of |
R207 | T1222 | T1221 | amod | human,defects |
R208 | T1223 | T1221 | amod | congenital,defects |
R209 | T1224 | T1221 | amod | diaphragmatic,defects |
R214 | T1229 | T1211 | conj | validates,is |
R215 | T1230 | T1228 | prep | for,necessity |
R216 | T1231 | T1232 | amod | pulmonary,development |
R217 | T1232 | T1230 | pobj | development,for |
R221 | T1236 | T1234 | acl | have,hypothesis |
R222 | T1237 | T1236 | nsubj | neonates,have |
R223 | T1238 | T1237 | prep | with,neonates |
R224 | T1239 | T1240 | amod | congenital,hernia |
R226 | T1241 | T1240 | amod | diaphragmatic,hernia |
R227 | T1242 | T1236 | aux | may,have |
R228 | T1243 | T1236 | advmod | also,have |
R230 | T1245 | T1236 | dobj | abnormalities,have |
R231 | T1246 | T1245 | amod | pulmonary,abnormalities |
R232 | T1247 | T1245 | amod | developmental,abnormalities |
R234 | T1018 | T1024 | ccomp | are,is |
R237 | T2580 | T2581 | amod | Congenital,defects |
R238 | T2581 | T2583 | nsubj | defects,are |
R239 | T2582 | T2581 | amod | diaphragmatic,defects |
R240 | T2584 | T2585 | det | a,spectrum |
R241 | T2585 | T2583 | attr | spectrum,are |
R242 | T2586 | T2585 | prep | of,spectrum |
R243 | T2587 | T2588 | advmod | relatively,common |
R244 | T2588 | T2589 | amod | common,defects |
R245 | T2589 | T2586 | pobj | defects,of |
R246 | T2590 | T2589 | compound | birth,defects |
R247 | T2591 | T2583 | punct | .,are |
R248 | T2593 | T2594 | det | The,Bochdalek |
R249 | T2594 | T2595 | nsubj | Bochdalek,occur |
R250 | T2596 | T2594 | cc | or,Bochdalek |
R251 | T2597 | T2598 | amod | posterolateral,hernias |
R252 | T2598 | T2594 | conj | hernias,Bochdalek |
R253 | T2599 | T2594 | punct | (,Bochdalek |
R254 | T2600 | T2601 | advmod | often,referred |
R255 | T2601 | T2594 | acl | referred,Bochdalek |
R256 | T2602 | T2601 | prep | to,referred |
R257 | T2603 | T2601 | prep | as,referred |
R258 | T2604 | T2605 | amod | congenital,hernia |
R259 | T2605 | T2603 | pobj | hernia,as |
R260 | T2606 | T2605 | amod | diaphragmatic,hernia |
R261 | T2607 | T2605 | punct | [,hernia |
R262 | T2608 | T2605 | appos | CDH,hernia |
R263 | T2609 | T2594 | punct | ],Bochdalek |
R264 | T2610 | T2594 | punct | ),Bochdalek |
R265 | T2611 | T2595 | prep | in,occur |
R266 | T2612 | T2613 | quantmod | 1,"3,000" |
R267 | T2613 | T2615 | nummod | "3,000",births |
R268 | T2614 | T2613 | punct | /,"3,000" |
R269 | T2615 | T2611 | pobj | births,in |
R270 | T2616 | T2615 | amod | live,births |
R271 | T2617 | T2618 | punct | [,1 |
R272 | T2618 | T2595 | parataxis | 1,occur |
R273 | T2619 | T2618 | punct | ],1 |
R274 | T2620 | T2595 | punct | ", ",occur |
R275 | T2621 | T2595 | cc | and,occur |
R276 | T2622 | T2623 | mark | although,are |
R277 | T2623 | T2625 | advcl | are,have |
R278 | T2624 | T2623 | nsubj | these,are |
R279 | T2625 | T2595 | conj | have,occur |
R280 | T2626 | T2627 | det | the,type |
R281 | T2627 | T2623 | attr | type,are |
R282 | T2628 | T2629 | advmod | most,common |
R283 | T2629 | T2627 | amod | common,type |
R284 | T2630 | T2627 | prep | of,type |
R285 | T2631 | T2632 | amod | diaphragmatic,defect |
R286 | T2632 | T2630 | pobj | defect,of |
R287 | T2633 | T2627 | acl | presenting,type |
R288 | T2634 | T2633 | prep | at,presenting |
R289 | T2635 | T2634 | pobj | birth,at |
R290 | T2636 | T2625 | punct | ", ",have |
R291 | T2637 | T2638 | amod | diaphragmatic,aplasia |
R292 | T2638 | T2625 | nsubj | aplasia,have |
R293 | T2639 | T2638 | cc | and,aplasia |
R294 | T2640 | T2641 | amod | diaphragmatic,defects |
R295 | T2641 | T2638 | conj | defects,aplasia |
R296 | T2642 | T2641 | compound | muscularization,defects |
R297 | T2643 | T2644 | punct | (,eventrations |
R298 | T2644 | T2641 | parataxis | eventrations,defects |
R299 | T2645 | T2644 | punct | ),eventrations |
R300 | T2646 | T2625 | aux | may,have |
R301 | T2647 | T2648 | det | a,presentation |
R302 | T2648 | T2625 | dobj | presentation,have |
R303 | T2649 | T2648 | amod | similar,presentation |
R304 | T2650 | T2648 | amod | clinical,presentation |
R305 | T2651 | T2625 | punct | .,have |
R306 | T2653 | T2654 | csubj | Making,be |
R307 | T2655 | T2656 | amod | specific,distinctions |
R308 | T2656 | T2653 | dobj | distinctions,Making |
R309 | T2657 | T2656 | amod | anatomic,distinctions |
R310 | T2658 | T2653 | prep | among,Making |
R311 | T2659 | T2660 | det | these,types |
R312 | T2660 | T2658 | pobj | types,among |
R313 | T2661 | T2660 | prep | of,types |
R314 | T2662 | T2661 | pobj | defects,of |
R315 | T2663 | T2654 | aux | can,be |
R316 | T2664 | T2654 | acomp | difficult,be |
R317 | T2665 | T2654 | prep | without,be |
R318 | T2666 | T2667 | amod | direct,examination |
R319 | T2667 | T2665 | pobj | examination,without |
R320 | T2668 | T2667 | amod | gross,examination |
R321 | T2669 | T2667 | punct | (,examination |
R322 | T2670 | T2667 | amod | intraoperative,examination |
R323 | T2671 | T2670 | cc | or,intraoperative |
R324 | T2672 | T2670 | conj | postmortem,intraoperative |
R325 | T2673 | T2667 | punct | ),examination |
R326 | T2674 | T2654 | punct | .,be |
R327 | T2676 | T2677 | amod | Pulmonary,hypoplasia |
R328 | T2677 | T2678 | nsubj | hypoplasia,causes |
R329 | T2679 | T2677 | amod | associated,hypoplasia |
R330 | T2680 | T2679 | prep | with,associated |
R331 | T2681 | T2682 | det | these,defects |
R332 | T2682 | T2680 | pobj | defects,with |
R333 | T2683 | T2682 | amod | diaphragmatic,defects |
R334 | T2684 | T2685 | amod | severe,mortality |
R335 | T2685 | T2678 | dobj | mortality,causes |
R336 | T2686 | T2685 | cc | and,mortality |
R337 | T2687 | T2685 | conj | morbidity,mortality |
R338 | T2688 | T2678 | punct | .,causes |
R339 | T2690 | T2691 | det | The,pathogenesis |
R340 | T2691 | T2692 | nsubjpass | pathogenesis,understood |
R341 | T2693 | T2691 | cc | and,pathogenesis |
R342 | T2694 | T2695 | amod | developmental,relationship |
R343 | T2695 | T2691 | conj | relationship,pathogenesis |
R344 | T2696 | T2695 | prep | between,relationship |
R345 | T2697 | T2698 | amod | diaphragmatic,defects |
R346 | T2698 | T2696 | pobj | defects,between |
R347 | T2699 | T2698 | cc | and,defects |
R348 | T2700 | T2701 | amod | pulmonary,hypoplasia |
R349 | T2701 | T2698 | conj | hypoplasia,defects |
R350 | T2702 | T2692 | auxpass | is,understood |
R351 | T2703 | T2692 | neg | not,understood |
R352 | T2704 | T2692 | punct | .,understood |
R353 | T2706 | T2707 | mark | Although,decreased |
R354 | T2707 | T2718 | advcl | decreased,reported |
R355 | T2708 | T2707 | nsubj | advances,decreased |
R356 | T2709 | T2708 | prep | in,advances |
R357 | T2710 | T2711 | det | the,management |
R358 | T2711 | T2709 | pobj | management,in |
R359 | T2712 | T2711 | amod | medical,management |
R360 | T2713 | T2711 | prep | of,management |
R361 | T2714 | T2715 | amod | pulmonary,hypoplasia |
R362 | T2715 | T2713 | pobj | hypoplasia,of |
R363 | T2716 | T2707 | aux | may,decreased |
R364 | T2717 | T2707 | aux | have,decreased |
R365 | T2719 | T2720 | det | the,mortality |
R366 | T2720 | T2707 | dobj | mortality,decreased |
R367 | T2721 | T2720 | amod | associated,mortality |
R368 | T2722 | T2721 | prep | with,associated |
R369 | T2723 | T2724 | compound | CDH,patients |
R370 | T2724 | T2722 | pobj | patients,with |
R371 | T2725 | T2726 | dep | who,survive |
R372 | T2726 | T2724 | relcl | survive,patients |
R373 | T2727 | T2728 | aux | to,receive |
R374 | T2728 | T2726 | advcl | receive,survive |
R375 | T2729 | T2728 | dobj | care,receive |
R376 | T2730 | T2728 | prep | at,receive |
R377 | T2731 | T2732 | amod | high,volume |
R378 | T2732 | T2734 | compound | volume,centers |
R379 | T2733 | T2732 | punct | -,volume |
R380 | T2734 | T2730 | pobj | centers,at |
R381 | T2735 | T2736 | punct | [,3 |
R382 | T2736 | T2707 | parataxis | 3,decreased |
R383 | T2737 | T2736 | nummod | 2,3 |
R384 | T2738 | T2736 | punct | ",",3 |
R385 | T2739 | T2736 | punct | ],3 |
R386 | T2740 | T2718 | punct | ", ",reported |
R387 | T2741 | T2742 | det | the,mortality |
R388 | T2742 | T2718 | nsubjpass | mortality,reported |
R389 | T2743 | T2744 | npadvmod | population,based |
R390 | T2744 | T2742 | amod | based,mortality |
R391 | T2745 | T2744 | punct | -,based |
R392 | T2746 | T2718 | aux | has,reported |
R393 | T2747 | T2718 | auxpass | been,reported |
R394 | T2748 | T2749 | aux | to,be |
R395 | T2749 | T2718 | xcomp | be,reported |
R396 | T2750 | T2751 | advmod | as,62 |
R397 | T2751 | T2754 | nummod | 62,% |
R398 | T2752 | T2751 | amod | great,62 |
R399 | T2753 | T2751 | quantmod | as,62 |
R400 | T2754 | T2749 | attr | %,be |
R401 | T2755 | T2718 | punct | ", ",reported |
R402 | T2756 | T2718 | cc | and,reported |
R403 | T2757 | T2758 | expl | there,are |
R404 | T2758 | T2718 | conj | are,reported |
R405 | T2759 | T2760 | det | a,number |
R406 | T2760 | T2758 | attr | number,are |
R407 | T2761 | T2760 | amod | large,number |
R408 | T2762 | T2760 | prep | of,number |
R409 | T2763 | T2762 | pobj | deaths,of |
R410 | T2764 | T2765 | amod | prior,to |
R411 | T2765 | T2758 | prep | to,are |
R412 | T2766 | T2765 | pobj | birth,to |
R413 | T2767 | T2765 | cc | or,to |
R414 | T2768 | T2765 | conj | to,to |
R415 | T2769 | T2768 | pobj | transfer,to |
R416 | T2770 | T2769 | prep | to,transfer |
R417 | T2771 | T2772 | det | a,facility |
R418 | T2772 | T2770 | pobj | facility,to |
R419 | T2773 | T2774 | amod | tertiary,care |
R420 | T2774 | T2772 | compound | care,facility |
R421 | T2775 | T2776 | punct | [,4 |
R422 | T2776 | T2758 | parataxis | 4,are |
R423 | T2777 | T2776 | punct | ],4 |
R424 | T2778 | T2718 | punct | .,reported |
R425 | T2780 | T2781 | mark | As,present |
R426 | T2781 | T2785 | advcl | present,centered |
R427 | T2782 | T2783 | det | these,patients |
R428 | T2783 | T2781 | nsubj | patients,present |
R429 | T2784 | T2781 | advmod | commonly,present |
R430 | T2786 | T2781 | prep | with,present |
R431 | T2787 | T2788 | amod | severe,failure |
R432 | T2788 | T2786 | pobj | failure,with |
R433 | T2789 | T2788 | amod | respiratory,failure |
R434 | T2790 | T2781 | prep | at,present |
R435 | T2791 | T2790 | pobj | birth,at |
R436 | T2792 | T2785 | punct | ", ",centered |
R437 | T2793 | T2785 | nsubjpass | therapy,centered |
R438 | T2794 | T2785 | aux | has,centered |
R439 | T2795 | T2785 | auxpass | been,centered |
R440 | T2796 | T2785 | prep | around,centered |
R441 | T2797 | T2796 | pcomp | developing,around |
R442 | T2798 | T2799 | amod | better,methods |
R443 | T2799 | T2797 | dobj | methods,developing |
R444 | T2800 | T2801 | aux | to,provide |
R445 | T2801 | T2799 | advcl | provide,methods |
R446 | T2802 | T2803 | amod | ventilatory,support |
R447 | T2803 | T2801 | dobj | support,provide |
R448 | T2804 | T2805 | mark | while,producing |
R449 | T2805 | T2801 | advcl | producing,provide |
R450 | T2806 | T2805 | neg | not,producing |
R451 | T2807 | T2808 | amod | further,injury |
R452 | T2808 | T2805 | dobj | injury,producing |
R453 | T2809 | T2808 | compound | lung,injury |
R454 | T2810 | T2785 | punct | .,centered |
R455 | T2812 | T2813 | amod | Extracorporeal,oxygenation |
R456 | T2813 | T2815 | nsubjpass | oxygenation,used |
R457 | T2814 | T2813 | compound | membrane,oxygenation |
R458 | T2816 | T2813 | punct | (,oxygenation |
R459 | T2817 | T2813 | appos | ECMO,oxygenation |
R460 | T2818 | T2813 | punct | ),oxygenation |
R461 | T2819 | T2815 | auxpass | is,used |
R462 | T2820 | T2815 | prep | in,used |
R463 | T2821 | T2822 | det | some,centers |
R464 | T2822 | T2820 | pobj | centers,in |
R465 | T2823 | T2824 | aux | to,provide |
R466 | T2824 | T2815 | advcl | provide,used |
R467 | T2825 | T2826 | det | an,period |
R468 | T2826 | T2824 | dobj | period,provide |
R469 | T2827 | T2826 | amod | extended,period |
R470 | T2828 | T2826 | prep | of,period |
R471 | T2829 | T2830 | amod | cardiopulmonary,bypass |
R472 | T2830 | T2828 | pobj | bypass,of |
R473 | T2831 | T2832 | punct | [,6 |
R474 | T2832 | T2815 | parataxis | 6,used |
R475 | T2833 | T2832 | nummod | 5,6 |
R476 | T2834 | T2832 | punct | ",",6 |
R477 | T2835 | T2832 | punct | ],6 |
R478 | T2836 | T2815 | punct | ", ",used |
R479 | T2837 | T2838 | mark | while,have |
R480 | T2838 | T2815 | advcl | have,used |
R481 | T2839 | T2840 | amod | other,centers |
R482 | T2840 | T2838 | nsubj | centers,have |
R483 | T2841 | T2838 | dobj | success,have |
R484 | T2842 | T2838 | advcl | using,have |
R485 | T2843 | T2844 | amod | other,techniques |
R486 | T2844 | T2842 | dobj | techniques,using |
R487 | T2845 | T2846 | amod | ventilatory,support |
R488 | T2846 | T2844 | compound | support,techniques |
R489 | T2847 | T2848 | punct | [,7 |
R490 | T2848 | T2838 | parataxis | 7,have |
R491 | T2849 | T2848 | punct | ],7 |
R492 | T2850 | T2815 | punct | .,used |
R493 | T2852 | T2853 | det | The,morbidity |
R494 | T2853 | T2854 | nsubj | morbidity,is |
R495 | T2855 | T2853 | prep | in,morbidity |
R496 | T2856 | T2855 | pobj | those,in |
R497 | T2857 | T2858 | dep | who,survive |
R498 | T2858 | T2856 | relcl | survive,those |
R499 | T2859 | T2854 | acomp | high,is |
R500 | T2860 | T2854 | punct | ", ",is |
R501 | T2861 | T2854 | cc | and,is |
R502 | T2862 | T2863 | amod | many,patients |
R503 | T2863 | T2864 | nsubj | patients,survive |
R504 | T2864 | T2854 | conj | survive,is |
R505 | T2865 | T2864 | prep | with,survive |
R506 | T2866 | T2867 | amod | chronic,insufficiency |
R507 | T2867 | T2865 | pobj | insufficiency,with |
R508 | T2868 | T2867 | amod | respiratory,insufficiency |
R509 | T2869 | T2867 | punct | ", ",insufficiency |
R510 | T2870 | T2871 | amod | cognitive,deficits |
R511 | T2871 | T2867 | conj | deficits,insufficiency |
R512 | T2872 | T2870 | cc | and,cognitive |
R513 | T2873 | T2870 | conj | neuromotor,cognitive |
R514 | T2874 | T2871 | punct | ", ",deficits |
R515 | T2875 | T2871 | cc | and,deficits |
R516 | T2876 | T2877 | compound | hearing,loss |
R517 | T2877 | T2871 | conj | loss,deficits |
R518 | T2878 | T2864 | prep | as,survive |
R519 | T2879 | T2880 | det | a,result |
R520 | T2880 | T2878 | pobj | result,as |
R521 | T2881 | T2880 | prep | of,result |
R522 | T2882 | T2883 | amod | necessary,interventions |
R523 | T2883 | T2881 | pobj | interventions,of |
R524 | T2884 | T2883 | amod | intensive,interventions |
R525 | T2885 | T2883 | cc | and,interventions |
R526 | T2886 | T2887 | amod | associated,abnormalities |
R527 | T2887 | T2883 | conj | abnormalities,interventions |
R528 | T2888 | T2887 | amod | structural,abnormalities |
R529 | T2889 | T2888 | cc | and,structural |
R530 | T2890 | T2888 | conj | irreversible,structural |
R531 | T2891 | T2887 | amod | developmental,abnormalities |
R532 | T2892 | T2893 | punct | [,8 |
R533 | T2893 | T2864 | parataxis | 8,survive |
R534 | T2894 | T2895 | punct | –,11 |
R535 | T2895 | T2893 | prep | 11,8 |
R536 | T2896 | T2893 | punct | ],8 |
R537 | T2897 | T2864 | punct | .,survive |
R538 | T2899 | T2900 | prep | To,been |
R539 | T2901 | T2899 | pobj | date,To |
R540 | T2902 | T2900 | punct | ", ",been |
R541 | T2903 | T2900 | expl | there,been |
R542 | T2904 | T2900 | aux | have,been |
R543 | T2905 | T2906 | det | no,mutations |
R544 | T2906 | T2900 | attr | mutations,been |
R545 | T2907 | T2906 | amod | specific,mutations |
R546 | T2908 | T2906 | acl | found,mutations |
R547 | T3015 | T2998 | xcomp | develop,is |
R548 | T3016 | T3017 | compound | animal,models |
R549 | T3017 | T3015 | dobj | models,develop |
R550 | T3018 | T3017 | prep | of,models |
R551 | T3019 | T3020 | amod | human,defects |
R552 | T3020 | T3018 | pobj | defects,of |
R553 | T3021 | T3020 | compound | birth,defects |
R554 | T3022 | T3015 | punct | ", ",develop |
R555 | T3023 | T3024 | mark | as,investigated |
R556 | T3024 | T3015 | advcl | investigated,develop |
R557 | T3025 | T3026 | det | the,abnormalities |
R558 | T3026 | T3024 | nsubjpass | abnormalities,investigated |
R559 | T2909 | T2910 | aux | to,be |
R560 | T3027 | T3026 | amod | specific,abnormalities |
R561 | T2910 | T2908 | xcomp | be,found |
R562 | T3028 | T3026 | amod | genetic,abnormalities |
R563 | T2911 | T2910 | acomp | associated,be |
R564 | T2912 | T2911 | prep | with,associated |
R565 | T3029 | T3026 | acl | found,abnormalities |
R566 | T2913 | T2914 | amod | nonsyndromic,defects |
R567 | T2914 | T2912 | pobj | defects,with |
R568 | T2915 | T2914 | amod | diaphragmatic,defects |
R569 | T3030 | T3029 | prep | in,found |
R570 | T2916 | T2914 | cc | and,defects |
R571 | T2917 | T2918 | amod | pulmonary,hypoplasia |
R572 | T3031 | T3032 | compound | animal,models |
R573 | T2918 | T2914 | conj | hypoplasia,defects |
R574 | T2919 | T2910 | prep | in,be |
R575 | T2920 | T2919 | pobj | humans,in |
R576 | T3032 | T3030 | pobj | models,in |
R577 | T2921 | T2900 | punct | .,been |
R578 | T3033 | T3024 | aux | can,investigated |
R579 | T2923 | T2924 | det | The,heritability |
R580 | T2924 | T2925 | nsubj | heritability,is |
R581 | T3034 | T3024 | advmod | then,investigated |
R582 | T2926 | T2924 | prep | of,heritability |
R583 | T2927 | T2928 | det | these,defects |
R584 | T3035 | T3024 | auxpass | be,investigated |
R585 | T2928 | T2926 | pobj | defects,of |
R586 | T2929 | T2925 | acomp | unclear,is |
R587 | T3036 | T3024 | prep | in,investigated |
R588 | T3037 | T3038 | amod | human,populations |
R589 | T2930 | T2925 | punct | ", ",is |
R590 | T2931 | T2932 | mark | as,limit |
R591 | T3038 | T3036 | pobj | populations,in |
R592 | T2932 | T2925 | advcl | limit,is |
R593 | T2933 | T2934 | det | the,morbidity |
R594 | T3039 | T2998 | punct | .,is |
R595 | T2934 | T2932 | nsubj | morbidity,limit |
R596 | T2935 | T2934 | amod | high,morbidity |
R597 | T2936 | T2934 | cc | and,morbidity |
R598 | T3041 | T3042 | nsubj | We,screened |
R599 | T2937 | T2934 | conj | mortality,morbidity |
R600 | T2938 | T2939 | det | the,collection |
R601 | T2939 | T2932 | dobj | collection,limit |
R602 | T2940 | T2939 | prep | of,collection |
R603 | T3043 | T3042 | dobj | mice,screened |
R604 | T2941 | T2942 | amod | multigenerational,families |
R605 | T2942 | T2940 | pobj | families,of |
R606 | T2943 | T2939 | prep | for,collection |
R607 | T2944 | T2943 | pobj | analysis,for |
R608 | T2945 | T2925 | punct | .,is |
R609 | T3044 | T3043 | acl | treated,mice |
R610 | T2947 | T2948 | det | The,etiologies |
R611 | T2948 | T2950 | nsubj | etiologies,are |
R612 | T2949 | T2948 | amod | genetic,etiologies |
R613 | T3045 | T3044 | prep | with,treated |
R614 | T2951 | T2950 | acomp | likely,are |
R615 | T2952 | T2953 | aux | to,be |
R616 | T3046 | T3047 | det | the,mutagen |
R617 | T2953 | T2951 | xcomp | be,likely |
R618 | T2954 | T2953 | acomp | complex,be |
R619 | T3047 | T3045 | pobj | mutagen,with |
R620 | T2955 | T2950 | cc | and,are |
R621 | T2956 | T2957 | advmod | probably,arise |
R622 | T2957 | T2950 | conj | arise,are |
R623 | T3048 | T3047 | amod | chemical,mutagen |
R624 | T2958 | T2957 | prep | from,arise |
R625 | T2959 | T2960 | amod | different,mutations |
R626 | T2960 | T2958 | pobj | mutations,from |
R627 | T3049 | T3050 | compound | N,ethyl |
R628 | T2961 | T2957 | prep | in,arise |
R629 | T2962 | T2963 | amod | various,parts |
R630 | T2963 | T2961 | pobj | parts,in |
R631 | T2964 | T2963 | prep | of,parts |
R632 | T3050 | T3047 | appos | ethyl,mutagen |
R633 | T2965 | T2966 | det | the,pathways |
R634 | T2966 | T2964 | pobj | pathways,of |
R635 | T3051 | T3050 | punct | -,ethyl |
R636 | T2967 | T2966 | amod | molecular,pathways |
R637 | T2968 | T2966 | amod | developmental,pathways |
R638 | T2969 | T2966 | acl | required,pathways |
R639 | T3052 | T3050 | punct | -,ethyl |
R640 | T2970 | T2969 | prep | for,required |
R641 | T2971 | T2972 | amod | diaphragmatic,development |
R642 | T2972 | T2970 | pobj | development,for |
R643 | T3053 | T3054 | compound | N,nitrosourea |
R644 | T2973 | T2950 | punct | .,are |
R645 | T3054 | T3050 | appos | nitrosourea,ethyl |
R646 | T2975 | T2976 | advmod | Indeed,are |
R647 | T3055 | T3054 | punct | -,nitrosourea |
R648 | T2977 | T2976 | punct | ", ",are |
R649 | T2978 | T2976 | expl | there,are |
R650 | T2979 | T2980 | amod | numerous,reports |
R651 | T3056 | T3050 | punct | (,ethyl |
R652 | T2980 | T2976 | attr | reports,are |
R653 | T2981 | T2980 | acl | implicating,reports |
R654 | T2982 | T2983 | amod | different,abnormalities |
R655 | T2983 | T2981 | dobj | abnormalities,implicating |
R656 | T3057 | T3050 | appos | ENU,ethyl |
R657 | T2984 | T2983 | amod | chromosomal,abnormalities |
R658 | T2985 | T2981 | prep | in,implicating |
R659 | T2986 | T2987 | det | the,pathogenesis |
R660 | T2987 | T2985 | pobj | pathogenesis,in |
R661 | T2988 | T2987 | prep | of,pathogenesis |
R662 | T3058 | T3042 | punct | ),screened |
R663 | T2989 | T2988 | pobj | CDH,of |
R664 | T2990 | T2991 | punct | [,13 |
R665 | T2991 | T2976 | parataxis | 13,are |
R666 | T3059 | T3042 | prep | for,screened |
R667 | T2992 | T2991 | nummod | 12,13 |
R668 | T2993 | T2991 | punct | ",",13 |
R669 | T2994 | T2991 | punct | ],13 |
R670 | T3060 | T3059 | pobj | lines,for |
R671 | T2995 | T2976 | punct | .,are |
R672 | T3061 | T3060 | prep | with,lines |
R673 | T2997 | T2998 | prep | Given,is |
R674 | T2999 | T3000 | det | the,difficulty |
R675 | T3062 | T3063 | amod | developmental,defects |
R676 | T3000 | T2997 | pobj | difficulty,Given |
R677 | T3001 | T3000 | prep | of,difficulty |
R678 | T3002 | T3001 | pcomp | studying,of |
R679 | T3063 | T3061 | pobj | defects,with |
R680 | T3003 | T3004 | amod | lethal,abnormalities |
R681 | T3004 | T3002 | dobj | abnormalities,studying |
R682 | T3064 | T3065 | dep | that,present |
R683 | T3005 | T3004 | amod | developmental,abnormalities |
R684 | T3006 | T3002 | prep | in,studying |
R685 | T3007 | T3006 | pobj | humans,in |
R686 | T3065 | T3063 | relcl | present,defects |
R687 | T3008 | T2998 | punct | ", ",is |
R688 | T3009 | T2998 | nsubj | it,is |
R689 | T3010 | T2998 | prep | of,is |
R690 | T3066 | T3065 | prep | in,present |
R691 | T3011 | T3012 | amod | great,utility |
R692 | T3012 | T3010 | pobj | utility,of |
R693 | T3067 | T3068 | det | the,period |
R694 | T3013 | T3012 | amod | potential,utility |
R695 | T3014 | T3015 | aux | to,develop |
R696 | T3068 | T3066 | pobj | period,in |
R697 | T3069 | T3068 | amod | perinatal,period |
R698 | T3070 | T3071 | punct | [,14 |
R699 | T3071 | T3042 | parataxis | 14,screened |
R700 | T3072 | T3071 | punct | ],14 |
R701 | T3073 | T3042 | punct | .,screened |
R702 | T3075 | T3076 | prep | From,identified |
R703 | T3121 | T3119 | dobj | mutation,revealed |
R704 | T3122 | T3119 | prep | in,revealed |
R705 | T3123 | T3124 | det | a,site |
R706 | T3124 | T3122 | pobj | site,in |
R707 | T3125 | T3124 | compound | splice,site |
R708 | T3126 | T3124 | compound | donor,site |
R709 | T3077 | T3078 | det | this,screen |
R710 | T3127 | T3128 | dep | that,generates |
R711 | T3128 | T3124 | relcl | generates,site |
R712 | T3129 | T3130 | det | an,transcript |
R713 | T3130 | T3128 | dobj | transcript,generates |
R714 | T3131 | T3130 | amod | abnormal,transcript |
R715 | T3078 | T3075 | pobj | screen,From |
R716 | T3132 | T3130 | acl | encoding,transcript |
R717 | T3133 | T3134 | det | a,protein |
R718 | T3134 | T3132 | dobj | protein,encoding |
R719 | T3079 | T3076 | punct | ", ",identified |
R720 | T3135 | T3134 | amod | truncated,protein |
R721 | T3136 | T3119 | punct | .,revealed |
R722 | T3080 | T3076 | nsubj | we,identified |
R723 | T3138 | T3139 | det | This,result |
R724 | T3139 | T3140 | nsubj | result,suggested |
R725 | T3081 | T3082 | det | a,line |
R726 | T3141 | T3142 | mark | that,examine |
R727 | T3142 | T3140 | ccomp | examine,suggested |
R728 | T3082 | T3076 | dobj | line,identified |
R729 | T3143 | T3142 | nsubj | we,examine |
R730 | T3144 | T3145 | det | the,gene |
R731 | T3083 | T3082 | prep | of,line |
R732 | T3145 | T3142 | dobj | gene,examine |
R733 | T3146 | T3145 | amod | orthologous,gene |
R734 | T3147 | T3142 | prep | in,examine |
R735 | T3084 | T3083 | pobj | mice,of |
R736 | T3148 | T3147 | pobj | humans,in |
R737 | T3149 | T3148 | prep | with,humans |
R738 | T3150 | T3151 | amod | similar,defects |
R739 | T3085 | T3084 | acl | carrying,mice |
R740 | T3151 | T3149 | pobj | defects,with |
R741 | T3152 | T3151 | amod | developmental,defects |
R742 | T3086 | T3087 | det | a,mutation |
R743 | T3153 | T3140 | punct | ", ",suggested |
R744 | T3154 | T3140 | cc | and,suggested |
R745 | T3155 | T3156 | nsubj | we,report |
R746 | T3087 | T3085 | dobj | mutation,carrying |
R747 | T3156 | T3140 | conj | report,suggested |
R748 | T3157 | T3158 | det | the,finding |
R749 | T3088 | T3087 | amod | recessive,mutation |
R750 | T3158 | T3156 | dobj | finding,report |
R751 | T3159 | T3158 | prep | of,finding |
R752 | T3160 | T3161 | det | a,mutation |
R753 | T3089 | T3090 | dep | that,results |
R754 | T3161 | T3159 | pobj | mutation,of |
R755 | T3162 | T3163 | advmod | de,novo |
R756 | T3163 | T3161 | amod | novo,mutation |
R757 | T3164 | T3161 | compound | nonsense,mutation |
R758 | T3165 | T3158 | prep | in,finding |
R759 | T3166 | T3165 | pobj | FOG2,in |
R760 | T3090 | T3087 | relcl | results,mutation |
R761 | T3167 | T3158 | prep | in,finding |
R762 | T3168 | T3169 | det | a,patient |
R763 | T3091 | T3090 | prep | in,results |
R764 | T3169 | T3167 | pobj | patient,in |
R765 | T3170 | T3171 | dep | who,died |
R766 | T3171 | T3169 | relcl | died,patient |
R767 | T3172 | T3171 | prep | at,died |
R768 | T3092 | T3093 | amod | primary,hypoplasia |
R769 | T3173 | T3172 | pobj | birth,at |
R770 | T3174 | T3171 | prep | with,died |
R771 | T3093 | T3091 | pobj | hypoplasia,in |
R772 | T3175 | T3176 | det | a,defect |
R773 | T3176 | T3174 | pobj | defect,with |
R774 | T3177 | T3176 | amod | diaphragmatic,defect |
R775 | T3178 | T3176 | cc | and,defect |
R776 | T3094 | T3093 | amod | pulmonary,hypoplasia |
R777 | T3179 | T3180 | amod | severe,hypoplasia |
R778 | T3180 | T3176 | conj | hypoplasia,defect |
R779 | T3181 | T3180 | amod | pulmonary,hypoplasia |
R780 | T3095 | T3093 | cc | and,hypoplasia |
R781 | T3182 | T3156 | punct | .,report |
R782 | T3096 | T3097 | amod | abnormal,development |
R783 | T3184 | T3185 | nsubj | This,is |
R784 | T3186 | T3187 | det | the,mutation |
R785 | T3097 | T3093 | conj | development,hypoplasia |
R786 | T3098 | T3097 | amod | diaphragmatic,development |
R787 | T3099 | T3098 | cc | and,diaphragmatic |
R788 | T3187 | T3185 | attr | mutation,is |
R789 | T3100 | T3098 | conj | cardiac,diaphragmatic |
R790 | T3188 | T3187 | amod | first,mutation |
R791 | T3189 | T3187 | amod | reported,mutation |
R792 | T3190 | T3187 | amod | associated,mutation |
R793 | T3101 | T3076 | punct | .,identified |
R794 | T3191 | T3190 | prep | with,associated |
R795 | T3192 | T3193 | det | these,abnormalities |
R796 | T3193 | T3191 | pobj | abnormalities,with |
R797 | T3103 | T3104 | amod | Positional,analysis |
R798 | T3194 | T3185 | prep | in,is |
R799 | T3195 | T3196 | det | a,human |
R800 | T3196 | T3194 | pobj | human,in |
R801 | T3197 | T3185 | punct | .,is |
R802 | T3104 | T3106 | nsubj | analysis,identified |
R803 | T3199 | T3200 | nsubj | We,present |
R804 | T3105 | T3104 | compound | cloning,analysis |
R805 | T3201 | T3202 | amod | additional,data |
R806 | T3202 | T3200 | dobj | data,present |
R807 | T3107 | T3106 | dobj | Fog2,identified |
R808 | T3203 | T3204 | dep | that,provide |
R809 | T3204 | T3202 | relcl | provide,data |
R810 | T3205 | T3206 | amod | direct,evidence |
R811 | T3206 | T3204 | dobj | evidence,provide |
R812 | T3207 | T3208 | mark | that,be |
R813 | T3208 | T3206 | acl | be,evidence |
R814 | T3108 | T3109 | punct | (,Zfpm2 |
R815 | T3209 | T3210 | amod | pulmonary,hypoplasia |
R816 | T3210 | T3208 | nsubj | hypoplasia,be |
R817 | T3109 | T3107 | parataxis | Zfpm2,Fog2 |
R818 | T3211 | T3208 | aux | may,be |
R819 | T3212 | T3213 | det | a,component |
R820 | T3213 | T3208 | attr | component,be |
R821 | T3110 | T3109 | punct | ),Zfpm2 |
R822 | T3214 | T3213 | amod | primary,component |
R823 | T3215 | T3213 | prep | of,component |
R824 | T3216 | T3217 | det | this,spectrum |
R825 | T3111 | T3106 | prep | as,identified |
R826 | T3217 | T3215 | pobj | spectrum,of |
R827 | T3218 | T3217 | prep | of,spectrum |
R828 | T3219 | T3218 | pobj | disorders,of |
R829 | T3112 | T3113 | det | a,candidate |
R830 | T3220 | T3200 | punct | .,present |
R831 | T3113 | T3111 | pobj | candidate,as |
R832 | T3114 | T3113 | amod | likely,candidate |
R833 | T3115 | T3106 | punct | ", ",identified |
R834 | T3116 | T3106 | cc | and,identified |
R835 | T3117 | T3118 | compound | DNA,sequencing |
R836 | T3118 | T3119 | nsubj | sequencing,revealed |
R837 | T3119 | T3106 | conj | revealed,identified |
R838 | T3120 | T3121 | det | a,mutation |
R839 | T5357 | T5356 | prep | of,Identification |
R840 | T5358 | T5359 | det | the,Mutation |
R841 | T5359 | T5357 | pobj | Mutation,of |
R842 | T5360 | T5361 | amod | little,lung |
R843 | T5361 | T5359 | compound | lung,Mutation |
R844 | T5362 | T5356 | prep | in,Identification |
R845 | T5363 | T5362 | pobj | Fog2,in |
R846 | T5365 | T5366 | nsubj | We,screened |
R847 | T5367 | T5368 | amod | third,generation |
R848 | T5368 | T5370 | compound | generation,progeny |
R849 | T5369 | T5368 | punct | -,generation |
R850 | T5370 | T5366 | dobj | progeny,screened |
R851 | T5371 | T5370 | prep | of,progeny |
R852 | T5372 | T5373 | npadvmod | ENU,mutagenized |
R853 | T5373 | T5375 | amod | mutagenized,mice |
R854 | T5374 | T5373 | punct | -,mutagenized |
R855 | T5375 | T5371 | pobj | mice,of |
R856 | T5376 | T5366 | prep | at,screened |
R857 | T5377 | T5378 | amod | embryonic,day |
R858 | T5378 | T5376 | pobj | day,at |
R859 | T5379 | T5378 | nummod | 18.5,day |
R860 | T5380 | T5378 | punct | (,day |
R861 | T5381 | T5378 | appos | E18.5,day |
R862 | T5382 | T5366 | punct | ),screened |
R863 | T5383 | T5366 | prep | for,screened |
R864 | T5384 | T5385 | amod | abnormal,phenotypes |
R865 | T5385 | T5383 | pobj | phenotypes,for |
R866 | T5386 | T5385 | amod | developmental,phenotypes |
R867 | T5387 | T5388 | punct | [,14 |
R868 | T5388 | T5366 | parataxis | 14,screened |
R869 | T5389 | T5388 | punct | ],14 |
R870 | T5390 | T5366 | punct | .,screened |
R871 | T5392 | T5393 | nummod | One,line |
R872 | T5393 | T5394 | nsubjpass | line,found |
R873 | T5395 | T5393 | prep | of,line |
R874 | T5396 | T5395 | pobj | mice,of |
R875 | T5397 | T5394 | auxpass | was,found |
R876 | T5398 | T5399 | aux | to,have |
R877 | T5399 | T5394 | xcomp | have,found |
R878 | T5400 | T5401 | amod | multiple,embryos |
R879 | T5401 | T5399 | dobj | embryos,have |
R880 | T5402 | T5401 | prep | in,embryos |
R881 | T5403 | T5404 | amod | independent,litters |
R882 | T5404 | T5402 | pobj | litters,in |
R883 | T5405 | T5406 | dep | that,displayed |
R884 | T5406 | T5401 | relcl | displayed,embryos |
R885 | T5407 | T5408 | amod | pulmonary,hypoplasia |
R886 | T5408 | T5406 | dobj | hypoplasia,displayed |
R887 | T5409 | T5408 | cc | and,hypoplasia |
R888 | T5410 | T5411 | det | a,diaphragm |
R889 | T5411 | T5408 | conj | diaphragm,hypoplasia |
R890 | T5412 | T5411 | amod | thin,diaphragm |
R891 | T5413 | T5394 | punct | .,found |
R892 | T5415 | T5416 | det | The,mutation |
R893 | T5416 | T5417 | nsubjpass | mutation,mapped |
R894 | T5418 | T5416 | punct | ", ",mutation |
R895 | T5419 | T5420 | dep | which,called |
R896 | T5420 | T5416 | relcl | called,mutation |
R897 | T5421 | T5420 | nsubj | we,called |
R898 | T5422 | T5423 | amod | little,lung |
R899 | T5423 | T5420 | oprd | lung,called |
R900 | T5424 | T5423 | punct | (,lung |
R901 | T5425 | T5423 | appos | lil,lung |
R902 | T5426 | T5423 | punct | ),lung |
R903 | T5427 | T5417 | punct | ", ",mapped |
R904 | T5428 | T5417 | auxpass | was,mapped |
R905 | T5429 | T5417 | prep | to,mapped |
R906 | T5430 | T5429 | pobj | Chromosome,to |
R907 | T5431 | T5430 | nummod | 15,Chromosome |
R908 | T5432 | T5417 | prep | by,mapped |
R909 | T5433 | T5432 | pcomp | utilizing,by |
R910 | T5434 | T5435 | det | a,strategy |
R911 | T5435 | T5433 | dobj | strategy,utilizing |
R912 | T5442 | T5441 | nsubj | data,shown |
R913 | T5436 | T5435 | prep | of,strategy |
R914 | T5443 | T5441 | neg | not,shown |
R915 | T5444 | T5441 | punct | ),shown |
R916 | T5437 | T5438 | amod | interval,analysis |
R917 | T5445 | T5446 | punct | [,15 |
R918 | T5446 | T5417 | parataxis | 15,mapped |
R919 | T5438 | T5436 | pobj | analysis,of |
R920 | T5447 | T5446 | punct | ],15 |
R921 | T5448 | T5417 | punct | .,mapped |
R922 | T5439 | T5438 | compound | haplotype,analysis |
R923 | T5450 | T5451 | prep | For,analyzed |
R924 | T5440 | T5441 | punct | (,shown |
R925 | T5452 | T5453 | amod | high,resolution |
R926 | T5441 | T5417 | parataxis | shown,mapped |
R927 | T5453 | T5455 | compound | resolution,mapping |
R928 | T5454 | T5453 | punct | -,resolution |
R929 | T5455 | T5450 | pobj | mapping,For |
R930 | T5548 | T5549 | compound | flanking,markers |
R931 | T5456 | T5451 | punct | ", ",analyzed |
R932 | T5457 | T5458 | compound | F2,progeny |
R933 | T5458 | T5451 | nsubjpass | progeny,analyzed |
R934 | T5549 | T5544 | dobj | markers,D15Mit5 |
R935 | T5459 | T5458 | prep | from,progeny |
R936 | T5460 | T5461 | nummod | two,crosses |
R937 | T5461 | T5459 | pobj | crosses,from |
R938 | T5550 | T5535 | punct | .,established |
R939 | T5462 | T5451 | auxpass | were,analyzed |
R940 | T5463 | T5451 | punct | .,analyzed |
R941 | T5465 | T5466 | prep | In,defined |
R942 | T5552 | T5553 | det | The,phenotype |
R943 | T5467 | T5468 | nummod | 450,progeny |
R944 | T5468 | T5465 | pobj | progeny,In |
R945 | T5469 | T5468 | prep | of,progeny |
R946 | T5470 | T5471 | det | an,intercross |
R947 | T5553 | T5555 | nsubjpass | phenotype,identified |
R948 | T5471 | T5469 | pobj | intercross,of |
R949 | T5472 | T5471 | prep | of,intercross |
R950 | T5473 | T5474 | nmod | F1,mice |
R951 | T5554 | T5553 | compound | lil,phenotype |
R952 | T5474 | T5472 | pobj | mice,of |
R953 | T5475 | T5476 | punct | (,J |
R954 | T5556 | T5555 | auxpass | was,identified |
R955 | T5476 | T5474 | nmod | J,mice |
R956 | T5477 | T5476 | nmod | A,J |
R957 | T5478 | T5476 | punct | /,J |
R958 | T5479 | T5476 | punct | ×,J |
R959 | T5480 | T5481 | compound | FVB,N |
R960 | T5481 | T5476 | appos | N,J |
R961 | T5557 | T5555 | prep | at,identified |
R962 | T5482 | T5481 | punct | /,N |
R963 | T5483 | T5476 | punct | ),J |
R964 | T5484 | T5474 | nmod | lil,mice |
R965 | T5485 | T5484 | punct | /,lil |
R966 | T5558 | T5557 | pobj | E18.5,at |
R967 | T5486 | T5484 | punct | +,lil |
R968 | T5487 | T5466 | punct | ", ",defined |
R969 | T5488 | T5489 | det | the,interval |
R970 | T5559 | T5560 | aux | to,have |
R971 | T5489 | T5466 | nsubjpass | interval,defined |
R972 | T5490 | T5489 | acl | containing,interval |
R973 | T5491 | T5492 | det | the,mutation |
R974 | T5560 | T5555 | xcomp | have,identified |
R975 | T5492 | T5490 | dobj | mutation,containing |
R976 | T5493 | T5466 | auxpass | was,defined |
R977 | T5494 | T5466 | prep | by,defined |
R978 | T5561 | T5562 | amod | bilateral,hypoplasia |
R979 | T5495 | T5496 | nummod | 19,recombinants |
R980 | T5496 | T5494 | pobj | recombinants,by |
R981 | T5497 | T5496 | prep | between,recombinants |
R982 | T5562 | T5560 | dobj | hypoplasia,have |
R983 | T5498 | T5497 | pobj | D15Mit220,between |
R984 | T5499 | T5498 | cc | and,D15Mit220 |
R985 | T5500 | T5498 | conj | D15Mit154,D15Mit220 |
R986 | T5563 | T5562 | amod | pulmonary,hypoplasia |
R987 | T5501 | T5466 | punct | .,defined |
R988 | T5564 | T5562 | cc | and,hypoplasia |
R989 | T5503 | T5504 | prep | Because,tested |
R990 | T5505 | T5503 | pcomp | of,Because |
R991 | T5506 | T5507 | det | the,lack |
R992 | T5565 | T5566 | det | an,diaphragm |
R993 | T5507 | T5503 | pobj | lack,Because |
R994 | T5508 | T5507 | prep | of,lack |
R995 | T5509 | T5510 | amod | informative,markers |
R996 | T5510 | T5508 | pobj | markers,of |
R997 | T5566 | T5562 | conj | diaphragm,hypoplasia |
R998 | T5567 | T5566 | amod | abnormal,diaphragm |
R999 | T5511 | T5507 | prep | within,lack |
R1000 | T5568 | T5555 | punct | .,identified |
R1001 | T5512 | T5513 | det | this,interval |
R1002 | T5570 | T5571 | amod | Pulmonary,hypoplasia |
R1003 | T5513 | T5511 | pobj | interval,within |
R1004 | T5514 | T5504 | punct | ", ",tested |
R1005 | T5515 | T5516 | quantmod | an,39 |
R1006 | T5516 | T5518 | nummod | 39,progeny |
R1007 | T5571 | T5572 | nsubj | hypoplasia,was |
R1008 | T5517 | T5516 | amod | additional,39 |
R1009 | T5518 | T5504 | nsubjpass | progeny,tested |
R1010 | T5573 | T5572 | acomp | apparent,was |
R1011 | T5519 | T5518 | compound | F2,progeny |
R1012 | T5520 | T5518 | prep | from,progeny |
R1013 | T5521 | T5522 | det | an,cross |
R1014 | T5574 | T5572 | prep | in,was |
R1015 | T5522 | T5520 | pobj | cross,from |
R1016 | T5523 | T5524 | nmod | A,J |
R1017 | T5524 | T5522 | nmod | J,cross |
R1018 | T5575 | T5576 | det | all,mice |
R1019 | T5525 | T5524 | punct | /,J |
R1020 | T5526 | T5524 | punct | ×,J |
R1021 | T5576 | T5574 | pobj | mice,in |
R1022 | T5527 | T5528 | compound | C57BL,6J |
R1023 | T5528 | T5524 | appos | 6J,J |
R1024 | T5529 | T5528 | punct | /,6J |
R1025 | T5530 | T5504 | auxpass | were,tested |
R1026 | T5577 | T5576 | compound | mutant,mice |
R1027 | T5531 | T5504 | punct | .,tested |
R1028 | T5578 | T5579 | dep | that,survived |
R1029 | T5533 | T5534 | det | The,identification |
R1030 | T5534 | T5535 | nsubj | identification,established |
R1031 | T5579 | T5576 | relcl | survived,mice |
R1032 | T5536 | T5534 | prep | of,identification |
R1033 | T5537 | T5538 | nummod | two,recombinants |
R1034 | T5538 | T5536 | pobj | recombinants,of |
R1035 | T5539 | T5535 | dobj | D15Mit85,established |
R1036 | T5580 | T5579 | prep | to,survived |
R1037 | T5540 | T5535 | prep | as,established |
R1038 | T5541 | T5542 | det | the,proximal |
R1039 | T5542 | T5540 | pobj | proximal,as |
R1040 | T5581 | T5580 | pobj | birth,to |
R1041 | T5543 | T5535 | cc | and,established |
R1042 | T5544 | T5535 | conj | D15Mit5,established |
R1043 | T5582 | T5572 | punct | .,was |
R1044 | T5545 | T5544 | prep | as,D15Mit5 |
R1045 | T5546 | T5547 | det | the,distal |
R1046 | T5547 | T5545 | pobj | distal,as |
R1047 | T5584 | T5585 | prep | In,were |
R1048 | T5586 | T5587 | det | a,comparison |
R1049 | T5587 | T5584 | pobj | comparison,In |
R1050 | T5655 | T5653 | prep | from,lungs |
R1051 | T5656 | T5657 | compound | mutant,mice |
R1052 | T5588 | T5587 | prep | between,comparison |
R1053 | T5657 | T5655 | pobj | mice,from |
R1054 | T5658 | T5654 | aux | were,lacking |
R1055 | T5659 | T5660 | det | an,lobe |
R1056 | T5589 | T5590 | amod | wild,type |
R1057 | T5660 | T5654 | dobj | lobe,lacking |
R1058 | T5661 | T5660 | amod | accessory,lobe |
R1059 | T5590 | T5592 | nmod | type,mice |
R1060 | T5662 | T5654 | prep | on,lacking |
R1061 | T5663 | T5664 | det | the,side |
R1062 | T5664 | T5662 | pobj | side,on |
R1063 | T5591 | T5590 | punct | -,type |
R1064 | T5665 | T5664 | amod | right,side |
R1065 | T5592 | T5588 | pobj | mice,between |
R1066 | T5666 | T5654 | cc | and,lacking |
R1067 | T5667 | T5654 | conj | had,lacking |
R1068 | T5668 | T5667 | dobj | underdevelopment,had |
R1069 | T5669 | T5668 | prep | of,underdevelopment |
R1070 | T5593 | T5590 | cc | and,type |
R1071 | T5670 | T5671 | det | the,lobe |
R1072 | T5671 | T5669 | pobj | lobe,of |
R1073 | T5672 | T5671 | amod | anterior,lobe |
R1074 | T5594 | T5590 | conj | mutant,type |
R1075 | T5673 | T5671 | amod | right,lobe |
R1076 | T5674 | T5671 | amod | middle,lobe |
R1077 | T5595 | T5592 | acl | found,mice |
R1078 | T5675 | T5676 | punct | (,Figure |
R1079 | T5676 | T5667 | parataxis | Figure,had |
R1080 | T5677 | T5676 | nummod | 1A,Figure |
R1081 | T5596 | T5595 | oprd | dead,found |
R1082 | T5678 | T5676 | punct | ),Figure |
R1083 | T5679 | T5654 | punct | .,lacking |
R1084 | T5597 | T5595 | prep | on,found |
R1085 | T5681 | T5682 | nsubj | Diaphragms,were |
R1086 | T5683 | T5681 | prep | from,Diaphragms |
R1087 | T5598 | T5597 | pobj | day,on |
R1088 | T5684 | T5685 | compound | mutant,mice |
R1089 | T5685 | T5683 | pobj | mice,from |
R1090 | T5686 | T5685 | compound | lil,mice |
R1091 | T5599 | T5598 | nummod | one,day |
R1092 | T5600 | T5598 | prep | of,day |
R1093 | T5687 | T5682 | acomp | intact,were |
R1094 | T5688 | T5682 | punct | ", ",were |
R1095 | T5689 | T5682 | cc | but,were |
R1096 | T5601 | T5600 | pobj | life,of |
R1097 | T5690 | T5691 | nsubj | muscularization,was |
R1098 | T5691 | T5682 | conj | was,were |
R1099 | T5692 | T5691 | acomp | absent,was |
R1100 | T5693 | T5691 | prep | in,was |
R1101 | T5694 | T5695 | det | the,regions |
R1102 | T5695 | T5693 | pobj | regions,in |
R1103 | T5602 | T5585 | punct | ", ",were |
R1104 | T5696 | T5695 | amod | dorsal,regions |
R1105 | T5697 | T5691 | punct | .,was |
R1106 | T5603 | T5604 | compound | body,weights |
R1107 | T5699 | T5700 | nsubj | Myotubules,were |
R1108 | T5701 | T5700 | acomp | present,were |
R1109 | T5604 | T5605 | nsubj | weights,were |
R1110 | T5702 | T5700 | prep | in,were |
R1111 | T5703 | T5704 | det | a,distribution |
R1112 | T5704 | T5702 | pobj | distribution,in |
R1113 | T5705 | T5704 | amod | limited,distribution |
R1114 | T5605 | T5585 | ccomp | were,were |
R1115 | T5706 | T5705 | cc | and,limited |
R1116 | T5707 | T5705 | conj | abnormal,limited |
R1117 | T5708 | T5700 | punct | .,were |
R1118 | T5606 | T5605 | neg | not,were |
R1119 | T5710 | T5711 | advmod | More,specifically |
R1120 | T5607 | T5605 | acomp | different,were |
R1121 | T5711 | T5712 | advmod | specifically,radiate |
R1122 | T5713 | T5712 | punct | ", ",radiate |
R1123 | T5608 | T5585 | punct | ;,were |
R1124 | T5714 | T5712 | nsubj | myotubules,radiate |
R1125 | T5715 | T5712 | advmod | normally,radiate |
R1126 | T5716 | T5712 | prep | in,radiate |
R1127 | T5717 | T5718 | det | a,fashion |
R1128 | T5609 | T5585 | advmod | however,were |
R1129 | T5718 | T5716 | pobj | fashion,in |
R1130 | T5719 | T5718 | amod | mediolateral,fashion |
R1131 | T5610 | T5585 | punct | ", ",were |
R1132 | T5720 | T5721 | aux | to,meet |
R1133 | T5721 | T5712 | advcl | meet,radiate |
R1134 | T5722 | T5723 | det | the,walls |
R1135 | T5611 | T5612 | det | the,weights |
R1136 | T5723 | T5721 | dobj | walls,meet |
R1137 | T5724 | T5723 | amod | lateral,walls |
R1138 | T5725 | T5723 | compound | body,walls |
R1139 | T5726 | T5712 | punct | ", ",radiate |
R1140 | T5612 | T5585 | nsubj | weights,were |
R1141 | T5727 | T5712 | prep | with,radiate |
R1142 | T5728 | T5729 | det | a,paucity |
R1143 | T5613 | T5612 | compound | lung,weights |
R1144 | T5729 | T5727 | pobj | paucity,with |
R1145 | T5730 | T5729 | amod | normal,paucity |
R1146 | T5731 | T5729 | prep | of,paucity |
R1147 | T5614 | T5615 | advmod | significantly,lower |
R1148 | T5732 | T5733 | compound | muscle,fibers |
R1149 | T5733 | T5731 | pobj | fibers,of |
R1150 | T5734 | T5729 | prep | in,paucity |
R1151 | T5735 | T5736 | det | the,region |
R1152 | T5736 | T5734 | pobj | region,in |
R1153 | T5737 | T5736 | amod | central,region |
R1154 | T5738 | T5736 | amod | tendonous,region |
R1155 | T5615 | T5585 | acomp | lower,were |
R1156 | T5739 | T5712 | punct | .,radiate |
R1157 | T5616 | T5585 | prep | in,were |
R1158 | T5741 | T5742 | prep | In,radiated |
R1159 | T5617 | T5618 | det | the,mice |
R1160 | T5743 | T5744 | det | the,diaphragm |
R1161 | T5744 | T5741 | pobj | diaphragm,In |
R1162 | T5745 | T5744 | compound | mutant,diaphragm |
R1163 | T5746 | T5742 | punct | ", ",radiated |
R1164 | T5618 | T5616 | pobj | mice,in |
R1165 | T5747 | T5742 | nsubj | myotubules,radiated |
R1166 | T5748 | T5742 | prep | in,radiated |
R1167 | T5749 | T5750 | det | a,orientation |
R1168 | T5619 | T5618 | compound | mutant,mice |
R1169 | T5750 | T5748 | pobj | orientation,in |
R1170 | T5751 | T5752 | amod | dorsal,ventral |
R1171 | T5620 | T5585 | punct | .,were |
R1172 | T5752 | T5750 | amod | ventral,orientation |
R1173 | T5753 | T5752 | punct | –,ventral |
R1174 | T5754 | T5742 | punct | ", ",radiated |
R1175 | T5622 | T5623 | det | The,weight |
R1176 | T5755 | T5742 | cc | and,radiated |
R1177 | T5756 | T5757 | compound | muscle,tissue |
R1178 | T5757 | T5758 | nsubj | tissue,meet |
R1179 | T5758 | T5742 | conj | meet,radiated |
R1180 | T5623 | T5627 | nsubj | weight,was |
R1181 | T5759 | T5758 | aux | did,meet |
R1182 | T5624 | T5623 | amod | average,weight |
R1183 | T5625 | T5626 | compound | mutant,lung |
R1184 | T5626 | T5623 | compound | lung,weight |
R1185 | T5760 | T5758 | neg | not,meet |
R1186 | T5761 | T5762 | det | the,surface |
R1187 | T5628 | T5629 | quantmod | 9.6,2.5 |
R1188 | T5762 | T5758 | dobj | surface,meet |
R1189 | T5763 | T5762 | amod | entire,surface |
R1190 | T5764 | T5762 | prep | of,surface |
R1191 | T5765 | T5766 | det | the,walls |
R1192 | T5629 | T5631 | nummod | 2.5,mg |
R1193 | T5766 | T5764 | pobj | walls,of |
R1194 | T5767 | T5766 | compound | body,walls |
R1195 | T5768 | T5769 | punct | (,Figure |
R1196 | T5630 | T5629 | punct | ±,2.5 |
R1197 | T5769 | T5758 | parataxis | Figure,meet |
R1198 | T5770 | T5769 | nummod | 1B,Figure |
R1199 | T5771 | T5769 | punct | ),Figure |
R1200 | T5631 | T5627 | attr | mg,was |
R1201 | T5772 | T5758 | punct | .,meet |
R1202 | T5774 | T5775 | det | The,number |
R1203 | T5632 | T5633 | mark | while,was |
R1204 | T5775 | T5776 | nsubj | number,was |
R1205 | T5633 | T5627 | advcl | was,was |
R1206 | T5777 | T5775 | prep | of,number |
R1207 | T5778 | T5779 | compound | lil,mice |
R1208 | T5634 | T5635 | det | the,weight |
R1209 | T5779 | T5777 | pobj | mice,of |
R1210 | T5780 | T5779 | compound | mutant,mice |
R1211 | T5781 | T5782 | dep | that,survived |
R1212 | T5635 | T5633 | nsubj | weight,was |
R1213 | T5782 | T5779 | relcl | survived,mice |
R1214 | T5783 | T5782 | prep | to,survived |
R1215 | T5784 | T5783 | pobj | birth,to |
R1216 | T5636 | T5635 | amod | average,weight |
R1217 | T5785 | T5786 | amod | less,5 |
R1218 | T5786 | T5788 | nummod | 5,% |
R1219 | T5787 | T5786 | quantmod | than,5 |
R1220 | T5637 | T5638 | amod | wild,type |
R1221 | T5788 | T5776 | attr | %,was |
R1222 | T5789 | T5788 | prep | of,% |
R1223 | T5638 | T5640 | compound | type,lung |
R1224 | T5790 | T5791 | amod | total,progeny |
R1225 | T5791 | T5789 | pobj | progeny,of |
R1226 | T5792 | T5776 | punct | ", ",was |
R1227 | T5793 | T5794 | advmod | rather,than |
R1228 | T5639 | T5638 | punct | -,type |
R1229 | T5794 | T5776 | prep | than,was |
R1230 | T5795 | T5796 | det | the,% |
R1231 | T5640 | T5635 | compound | lung,weight |
R1232 | T5796 | T5794 | pobj | %,than |
R1233 | T5797 | T5796 | nummod | 25,% |
R1234 | T5641 | T5642 | quantmod | 26.4,4.6 |
R1235 | T5642 | T5644 | nummod | 4.6,mg |
R1236 | T5798 | T5796 | acl | expected,% |
R1237 | T5799 | T5798 | prep | for,expected |
R1238 | T5643 | T5642 | punct | ±,4.6 |
R1239 | T5800 | T5801 | det | a,mutation |
R1240 | T5801 | T5799 | pobj | mutation,for |
R1241 | T5802 | T5801 | amod | recessive,mutation |
R1242 | T5644 | T5633 | attr | mg,was |
R1243 | T5803 | T5776 | punct | .,was |
R1244 | T5645 | T5646 | punct | (,0.001 |
R1245 | T5805 | T5806 | nsubj | We,evaluated |
R1246 | T5807 | T5806 | dobj | litters,evaluated |
R1247 | T5646 | T5627 | parataxis | 0.001,was |
R1248 | T5808 | T5806 | prep | at,evaluated |
R1249 | T5809 | T5810 | amod | different,points |
R1250 | T5810 | T5808 | pobj | points,at |
R1251 | T5647 | T5646 | nsubj | p,0.001 |
R1252 | T5811 | T5810 | amod | embryonic,points |
R1253 | T5812 | T5810 | compound | time,points |
R1254 | T5813 | T5814 | aux | to,determine |
R1255 | T5814 | T5806 | advcl | determine,evaluated |
R1256 | T5815 | T5816 | mark | whether,was |
R1257 | T5816 | T5814 | ccomp | was,determine |
R1258 | T5648 | T5646 | punct | <,0.001 |
R1259 | T5817 | T5818 | det | the,number |
R1260 | T5818 | T5816 | nsubj | number,was |
R1261 | T5819 | T5818 | amod | reduced,number |
R1262 | T5820 | T5816 | prep | due,was |
R1263 | T5649 | T5646 | punct | ),0.001 |
R1264 | T5821 | T5820 | pcomp | to,due |
R1265 | T5822 | T5823 | amod | intra-uterine,demise |
R1266 | T5650 | T5627 | punct | .,was |
R1267 | T5823 | T5820 | pobj | demise,due |
R1268 | T5824 | T5806 | punct | .,evaluated |
R1269 | T5826 | T5827 | nsubjpass | Litters,collected |
R1270 | T5652 | T5653 | det | All,lungs |
R1271 | T5828 | T5827 | auxpass | were,collected |
R1272 | T5829 | T5827 | prep | at,collected |
R1273 | T5830 | T5829 | pobj | E12.5,at |
R1274 | T5653 | T5654 | nsubj | lungs,lacking |
R1275 | T5831 | T5830 | punct | ", ",E12.5 |
R1276 | T5832 | T5830 | nummod | 13.5,E12.5 |
R1277 | T5833 | T5830 | punct | ", ",E12.5 |
R1278 | T5867 | T5868 | det | a,rate |
R1279 | T5834 | T5830 | nummod | 15.5,E12.5 |
R1280 | T5835 | T5830 | punct | ", ",E12.5 |
R1281 | T5836 | T5830 | nummod | 17.5,E12.5 |
R1282 | T5837 | T5830 | punct | ", ",E12.5 |
R1283 | T5838 | T5830 | cc | and,E12.5 |
R1284 | T5839 | T5830 | conj | 18.5,E12.5 |
R1285 | T5840 | T5827 | punct | ", ",collected |
R1286 | T5841 | T5827 | cc | and,collected |
R1287 | T5842 | T5843 | nsubjpass | embryos,genotyped |
R1288 | T5868 | T5866 | dobj | rate,had |
R1289 | T5843 | T5827 | conj | genotyped,collected |
R1290 | T5844 | T5843 | auxpass | were,genotyped |
R1291 | T5845 | T5843 | cc | and,genotyped |
R1292 | T5869 | T5870 | advmod | progressively,higher |
R1293 | T5846 | T5843 | conj | evaluated,genotyped |
R1294 | T5847 | T5846 | prep | for,evaluated |
R1295 | T5848 | T5847 | pobj | evidence,for |
R1296 | T5870 | T5868 | amod | higher,rate |
R1297 | T5849 | T5848 | prep | of,evidence |
R1298 | T5850 | T5851 | amod | intra-uterine,demise |
R1299 | T5871 | T5868 | prep | of,rate |
R1300 | T5851 | T5849 | pobj | demise,of |
R1301 | T5852 | T5848 | punct | ", ",evidence |
R1302 | T5853 | T5848 | prep | including,evidence |
R1303 | T5872 | T5871 | pobj | demise,of |
R1304 | T5854 | T5855 | compound | growth,retardation |
R1305 | T5855 | T5853 | pobj | retardation,including |
R1306 | T5856 | T5855 | punct | ", ",retardation |
R1307 | T5857 | T5855 | conj | pallor,retardation |
R1308 | T5858 | T5857 | punct | ", ",pallor |
R1309 | T5873 | T5866 | prep | between,had |
R1310 | T5859 | T5857 | cc | and,pallor |
R1311 | T5860 | T5861 | compound | tissue,friability |
R1312 | T5874 | T5873 | pobj | E13.5,between |
R1313 | T5861 | T5857 | conj | friability,pallor |
R1314 | T5875 | T5874 | cc | and,E13.5 |
R1315 | T5862 | T5843 | punct | .,genotyped |
R1316 | T5876 | T5874 | conj | E15.5,E13.5 |
R1317 | T5864 | T5865 | compound | lil,embryos |
R1318 | T5865 | T5866 | nsubj | embryos,had |
R1319 | T5877 | T5866 | punct | .,had |
R1320 | T5879 | T5880 | prep | At,were |
R1321 | T5881 | T5879 | pobj | E12.5,At |
R1322 | T5972 | T5973 | advmod | only,embryo |
R1323 | T5973 | T5970 | nsubj | embryo,was |
R1324 | T5882 | T5880 | punct | ", ",were |
R1325 | T5974 | T5973 | nummod | one,embryo |
R1326 | T5975 | T5970 | acomp | viable,was |
R1327 | T5976 | T5953 | punct | .,were |
R1328 | T5883 | T5884 | quantmod | 20,87 |
R1329 | T5978 | T5979 | amod | Diaphragmatic,muscularization |
R1330 | T5979 | T5980 | nsubj | muscularization,was |
R1331 | T5884 | T5880 | nsubj | 87,were |
R1332 | T5981 | T5980 | acomp | abnormal,was |
R1333 | T5982 | T5980 | prep | in,was |
R1334 | T5885 | T5884 | quantmod | out,87 |
R1335 | T5983 | T5984 | det | all,mice |
R1336 | T5886 | T5884 | quantmod | of,87 |
R1337 | T5984 | T5982 | pobj | mice,in |
R1338 | T5887 | T5888 | punct | (,% |
R1339 | T5985 | T5984 | compound | mutant,mice |
R1340 | T5986 | T5984 | acl | examined,mice |
R1341 | T5987 | T5988 | punct | (,25 |
R1342 | T5988 | T5980 | parataxis | 25,was |
R1343 | T5888 | T5884 | parataxis | %,87 |
R1344 | T5989 | T5988 | nsubj | n,25 |
R1345 | T5990 | T5988 | punct | >,25 |
R1346 | T5991 | T5988 | punct | ),25 |
R1347 | T5889 | T5888 | nummod | 23,% |
R1348 | T5992 | T5980 | punct | .,was |
R1349 | T5890 | T5888 | punct | ),% |
R1350 | T5994 | T5995 | amod | Pulmonary,hypoplasia |
R1351 | T5995 | T5996 | nsubjpass | hypoplasia,observed |
R1352 | T5891 | T5880 | acomp | homozygous,were |
R1353 | T5997 | T5996 | auxpass | was,observed |
R1354 | T5998 | T5996 | prep | in,observed |
R1355 | T5999 | T6000 | nummod | 100,% |
R1356 | T5892 | T5891 | prep | for,homozygous |
R1357 | T6000 | T5998 | pobj | %,in |
R1358 | T6001 | T6000 | prep | of,% |
R1359 | T6002 | T6001 | pobj | mutants,of |
R1360 | T6003 | T6002 | acl | evaluated,mutants |
R1361 | T6004 | T6003 | prep | for,evaluated |
R1362 | T6005 | T6006 | det | that,phenotype |
R1363 | T5893 | T5894 | det | the,mutation |
R1364 | T6006 | T6004 | pobj | phenotype,for |
R1365 | T6007 | T6003 | prep | between,evaluated |
R1366 | T6008 | T6007 | pobj | E11.5,between |
R1367 | T5894 | T5892 | pobj | mutation,for |
R1368 | T6009 | T6008 | cc | and,E11.5 |
R1369 | T6010 | T6008 | conj | birth,E11.5 |
R1370 | T6011 | T6012 | punct | (,50 |
R1371 | T5895 | T5880 | punct | ", ",were |
R1372 | T6012 | T5996 | parataxis | 50,observed |
R1373 | T6013 | T6012 | nsubj | n,50 |
R1374 | T6014 | T6012 | punct | >,50 |
R1375 | T6015 | T6012 | punct | ),50 |
R1376 | T5896 | T5880 | cc | and,were |
R1377 | T6016 | T5996 | punct | .,observed |
R1378 | T5897 | T5898 | nsubj | all,appeared |
R1379 | T6018 | T6019 | nsubj | Examination,showed |
R1380 | T6020 | T6018 | prep | of,Examination |
R1381 | T5898 | T5880 | conj | appeared,were |
R1382 | T5899 | T5897 | prep | of,all |
R1383 | T6021 | T6022 | amod | cardiac,morphology |
R1384 | T5900 | T5899 | pobj | these,of |
R1385 | T6022 | T6020 | pobj | morphology,of |
R1386 | T6023 | T6024 | mark | that,had |
R1387 | T6024 | T6019 | ccomp | had,showed |
R1388 | T5901 | T5898 | oprd | viable,appeared |
R1389 | T6025 | T6024 | nsubj | hearts,had |
R1390 | T6026 | T6025 | prep | from,hearts |
R1391 | T5902 | T5880 | punct | .,were |
R1392 | T6027 | T6028 | compound | E15.5,mice |
R1393 | T5904 | T5905 | prep | At,were |
R1394 | T6028 | T6026 | pobj | mice,from |
R1395 | T6029 | T6030 | compound | lil,mutant |
R1396 | T6030 | T6028 | compound | mutant,mice |
R1397 | T6031 | T6032 | det | a,variety |
R1398 | T6032 | T6024 | dobj | variety,had |
R1399 | T5906 | T5904 | pobj | E13.5,At |
R1400 | T6033 | T6032 | prep | of,variety |
R1401 | T6034 | T6035 | amod | developmental,defects |
R1402 | T6035 | T6033 | pobj | defects,of |
R1403 | T6036 | T6032 | punct | ", ",variety |
R1404 | T5907 | T5905 | punct | ", ",were |
R1405 | T6037 | T6032 | prep | including,variety |
R1406 | T6038 | T6039 | amod | enlarged,cushions |
R1407 | T5908 | T5909 | quantmod | 13,49 |
R1408 | T5909 | T5905 | nsubj | 49,were |
R1409 | T6039 | T6037 | pobj | cushions,including |
R1410 | T6040 | T6038 | cc | and,enlarged |
R1411 | T6041 | T6042 | advmod | abnormally,developed |
R1412 | T6042 | T6038 | conj | developed,enlarged |
R1413 | T6043 | T6039 | amod | endocardial,cushions |
R1414 | T6044 | T6039 | punct | ", ",cushions |
R1415 | T5910 | T5909 | quantmod | of,49 |
R1416 | T6045 | T6046 | det | a,ventricle |
R1417 | T6046 | T6039 | conj | ventricle,cushions |
R1418 | T6047 | T6048 | amod | double,outlet |
R1419 | T5911 | T5912 | punct | (,% |
R1420 | T6048 | T6046 | nmod | outlet,ventricle |
R1421 | T6049 | T6048 | punct | -,outlet |
R1422 | T6050 | T6046 | amod | right,ventricle |
R1423 | T5912 | T5909 | parataxis | %,49 |
R1424 | T6051 | T6046 | punct | ", ",ventricle |
R1425 | T6052 | T6046 | cc | and,ventricle |
R1426 | T6053 | T6054 | det | a,canal |
R1427 | T5913 | T5912 | nummod | 27,% |
R1428 | T6054 | T6046 | conj | canal,ventricle |
R1429 | T6055 | T6054 | amod | complete,canal |
R1430 | T6056 | T6054 | amod | atrioventricular,canal |
R1431 | T5914 | T5912 | punct | ),% |
R1432 | T6057 | T6019 | punct | .,showed |
R1433 | T5915 | T5905 | acomp | mutant,were |
R1434 | T6059 | T6060 | det | The,myocardium |
R1435 | T6060 | T6061 | nsubj | myocardium,was |
R1436 | T5916 | T5905 | cc | and,were |
R1437 | T6062 | T6061 | advmod | also,was |
R1438 | T6063 | T6064 | advmod | poorly,developed |
R1439 | T5917 | T5918 | nsubj | two,died |
R1440 | T6064 | T6061 | acomp | developed,was |
R1441 | T6065 | T6061 | punct | ", ",was |
R1442 | T6066 | T6061 | prep | with,was |
R1443 | T6067 | T6066 | pobj | thinning,with |
R1444 | T5918 | T5905 | conj | died,were |
R1445 | T6068 | T6067 | prep | of,thinning |
R1446 | T6069 | T6070 | det | the,layer |
R1447 | T5919 | T5918 | aux | had,died |
R1448 | T6070 | T6068 | pobj | layer,of |
R1449 | T6071 | T6070 | amod | outer,layer |
R1450 | T6072 | T6070 | amod | compact,layer |
R1451 | T5920 | T5905 | punct | .,were |
R1452 | T6073 | T6067 | cc | and,thinning |
R1453 | T6074 | T6075 | amod | decreased,vascularity |
R1454 | T5922 | T5923 | prep | At,were |
R1455 | T6075 | T6067 | conj | vascularity,thinning |
R1456 | T6076 | T6061 | punct | .,was |
R1457 | T5924 | T5922 | pobj | E15.5,At |
R1458 | T5925 | T5923 | punct | ", ",were |
R1459 | T6078 | T6079 | det | The,cohort |
R1460 | T5926 | T5927 | quantmod | 22,91 |
R1461 | T6079 | T6080 | nsubj | cohort,had |
R1462 | T6081 | T6079 | prep | of,cohort |
R1463 | T6082 | T6083 | compound | mutant,mice |
R1464 | T6083 | T6081 | pobj | mice,of |
R1465 | T6084 | T6085 | dep | that,survived |
R1466 | T6085 | T6083 | relcl | survived,mice |
R1467 | T5927 | T5923 | nsubj | 91,were |
R1468 | T6086 | T6085 | prep | to,survived |
R1469 | T6087 | T6086 | pobj | birth,to |
R1470 | T6088 | T6080 | advmod | also,had |
R1471 | T5928 | T5927 | quantmod | out,91 |
R1472 | T6089 | T6090 | amod | cardiac,malformations |
R1473 | T6090 | T6080 | dobj | malformations,had |
R1474 | T6091 | T6090 | prep | including,malformations |
R1475 | T5929 | T5927 | quantmod | of,91 |
R1476 | T6092 | T6093 | amod | atrioventricular,canal |
R1477 | T6093 | T6095 | nmod | canal,type |
R1478 | T6094 | T6093 | punct | -,canal |
R1479 | T5930 | T5931 | punct | (,% |
R1480 | T6095 | T6097 | nmod | type,defects |
R1481 | T6096 | T6095 | punct | -,type |
R1482 | T5931 | T5927 | parataxis | %,91 |
R1483 | T6097 | T6091 | pobj | defects,including |
R1484 | T6098 | T6097 | amod | ventricular,defects |
R1485 | T6099 | T6097 | amod | septal,defects |
R1486 | T5932 | T5931 | nummod | 24,% |
R1487 | T6100 | T6097 | punct | ", ",defects |
R1488 | T6101 | T6102 | nmod | ostium,defects |
R1489 | T6102 | T6097 | conj | defects,defects |
R1490 | T5933 | T5931 | punct | ),% |
R1491 | T6103 | T6102 | nmod | primum,defects |
R1492 | T6104 | T6102 | amod | atrial,defects |
R1493 | T5934 | T5923 | acomp | mutant,were |
R1494 | T6105 | T6102 | amod | septal,defects |
R1495 | T6106 | T6102 | punct | ", ",defects |
R1496 | T6107 | T6102 | cc | and,defects |
R1497 | T5935 | T5923 | cc | and,were |
R1498 | T6108 | T6109 | amod | enlarged,atria |
R1499 | T6109 | T6102 | conj | atria,defects |
R1500 | T6110 | T6111 | punct | (,shown |
R1501 | T5936 | T5937 | det | the,majority |
R1502 | T6111 | T6080 | parataxis | shown,had |
R1503 | T6112 | T6111 | nsubj | data,shown |
R1504 | T5937 | T5938 | nsubj | majority,died |
R1505 | T6113 | T6111 | neg | not,shown |
R1506 | T6114 | T6111 | punct | ),shown |
R1507 | T6115 | T6080 | punct | .,had |
R1508 | T5938 | T5923 | conj | died,were |
R1509 | T6117 | T6118 | det | All,mutants |
R1510 | T6118 | T6119 | nsubj | mutants,had |
R1511 | T5939 | T5937 | prep | of,majority |
R1512 | T6120 | T6121 | advmod | specifically,evaluated |
R1513 | T6121 | T6118 | acl | evaluated,mutants |
R1514 | T6122 | T6121 | prep | for,evaluated |
R1515 | T6123 | T6124 | det | a,phenotype |
R1516 | T6124 | T6122 | pobj | phenotype,for |
R1517 | T5940 | T5941 | compound | mutant,embryos |
R1518 | T6125 | T6124 | amod | cardiac,phenotype |
R1519 | T5941 | T5939 | pobj | embryos,of |
R1520 | T6126 | T6127 | punct | (,10 |
R1521 | T6127 | T6118 | parataxis | 10,mutants |
R1522 | T6128 | T6127 | nsubj | n,10 |
R1523 | T5942 | T5943 | punct | (,22 |
R1524 | T6129 | T6127 | punct | =,10 |
R1525 | T6130 | T6127 | punct | ),10 |
R1526 | T5943 | T5937 | parataxis | 22,majority |
R1527 | T6131 | T6132 | amod | abnormal,development |
R1528 | T6132 | T6119 | dobj | development,had |
R1529 | T6133 | T6132 | amod | cardiac,development |
R1530 | T6134 | T6119 | punct | .,had |
R1531 | T5944 | T5943 | quantmod | 17,22 |
R1532 | T6136 | T6137 | nsubj | Examination,revealed |
R1533 | T5945 | T5943 | quantmod | out,22 |
R1534 | T6138 | T6136 | prep | of,Examination |
R1535 | T5946 | T5943 | quantmod | of,22 |
R1536 | T6139 | T6140 | det | the,region |
R1537 | T6140 | T6138 | pobj | region,of |
R1538 | T6141 | T6142 | nummod | 3,Mb |
R1539 | T6142 | T6140 | compound | Mb,region |
R1540 | T5947 | T5943 | quantmod | the,22 |
R1541 | T6143 | T6142 | punct | -,Mb |
R1542 | T6144 | T6140 | prep | between,region |
R1543 | T5948 | T5943 | punct | ),22 |
R1544 | T6145 | T6144 | pobj | D15Mit85,between |
R1545 | T6146 | T6145 | cc | and,D15Mit85 |
R1546 | T6147 | T6145 | conj | D15Mit5,D15Mit85 |
R1547 | T5949 | T5938 | aux | had,died |
R1548 | T6148 | T6140 | prep | in,region |
R1549 | T6149 | T6150 | compound | DNA,sequence |
R1550 | T6150 | T6151 | compound | sequence,databases |
R1551 | T5950 | T5938 | punct | .,died |
R1552 | T6151 | T6148 | pobj | databases,in |
R1553 | T6152 | T6153 | nummod | three,genes |
R1554 | T6153 | T6137 | dobj | genes,revealed |
R1555 | T5952 | T5953 | prep | By,were |
R1556 | T6154 | T6153 | amod | predicted,genes |
R1557 | T6155 | T6153 | cc | and,genes |
R1558 | T6156 | T6157 | nummod | four,genes |
R1559 | T6157 | T6153 | conj | genes,genes |
R1560 | T6158 | T6157 | amod | known,genes |
R1561 | T5954 | T5952 | pobj | E18.5,By |
R1562 | T6159 | T6157 | punct | ", ",genes |
R1563 | T6160 | T6157 | prep | including,genes |
R1564 | T6161 | T6160 | pobj | Fog2,including |
R1565 | T6162 | T6137 | punct | .,revealed |
R1566 | T6164 | T6165 | amod | Targeted,mutations |
R1567 | T5955 | T5953 | punct | ", ",were |
R1568 | T6165 | T6166 | nsubj | mutations,have |
R1569 | T6167 | T6165 | prep | of,mutations |
R1570 | T5956 | T5957 | quantmod | nine,29 |
R1571 | T6168 | T6167 | pobj | Fog2,of |
R1572 | T6169 | T6170 | amod | cardiac,defects |
R1573 | T6170 | T6166 | dobj | defects,have |
R1574 | T6171 | T6172 | advmod | strikingly,similar |
R1575 | T5957 | T5959 | nummod | 29,embryos |
R1576 | T6172 | T6170 | amod | similar,defects |
R1577 | T6173 | T6172 | prep | to,similar |
R1578 | T6174 | T6173 | pobj | those,to |
R1579 | T5958 | T5957 | quantmod | of,29 |
R1580 | T6175 | T6176 | nsubj | we,identified |
R1581 | T6176 | T6174 | advcl | identified,those |
R1582 | T5959 | T5953 | nsubj | embryos,were |
R1583 | T6177 | T6176 | prep | in,identified |
R1584 | T5960 | T5961 | punct | (,% |
R1585 | T6178 | T6179 | compound | lil,mice |
R1586 | T6179 | T6177 | pobj | mice,in |
R1587 | T6180 | T6179 | compound | mutant,mice |
R1588 | T6181 | T6170 | punct | ", ",defects |
R1589 | T5961 | T5959 | parataxis | %,embryos |
R1590 | T6182 | T6170 | prep | including,defects |
R1591 | T6183 | T6184 | amod | atrioventricular,defects |
R1592 | T5962 | T5961 | nummod | 31,% |
R1593 | T5963 | T5961 | punct | ),% |
R1594 | T5964 | T5953 | acomp | homozygous,were |
R1595 | T6184 | T6182 | pobj | defects,including |
R1596 | T5965 | T5964 | prep | for,homozygous |
R1597 | T6185 | T6184 | compound | canal,defects |
R1598 | T6186 | T6184 | punct | ", ",defects |
R1599 | T6187 | T6188 | amod | thinned,myocardium |
R1600 | T5966 | T5967 | det | the,mutation |
R1601 | T6188 | T6184 | conj | myocardium,defects |
R1602 | T6189 | T6188 | punct | ", ",myocardium |
R1603 | T6190 | T6188 | cc | and,myocardium |
R1604 | T5967 | T5965 | pobj | mutation,for |
R1605 | T6191 | T6192 | amod | absent,vasculature |
R1606 | T6192 | T6188 | conj | vasculature,myocardium |
R1607 | T6193 | T6192 | amod | coronary,vasculature |
R1608 | T5968 | T5953 | punct | ", ",were |
R1609 | T5969 | T5970 | prep | of,was |
R1610 | T6194 | T6195 | punct | [,16 |
R1611 | T5970 | T5953 | ccomp | was,were |
R1612 | T6195 | T6166 | parataxis | 16,have |
R1613 | T5971 | T5969 | pobj | which,of |
R1614 | T6196 | T6195 | punct | ],16 |
R1615 | T6197 | T6166 | punct | .,have |
R1616 | T6290 | T6291 | det | a,codon |
R1617 | T6199 | T6200 | compound | RT,PCR |
R1618 | T6200 | T6202 | compound | PCR,amplification |
R1619 | T6201 | T6200 | punct | -,PCR |
R1620 | T6202 | T6203 | nsubj | amplification,revealed |
R1621 | T6204 | T6202 | prep | of,amplification |
R1622 | T6205 | T6206 | det | the,portion |
R1623 | T6206 | T6204 | pobj | portion,of |
R1624 | T6207 | T6206 | amod | proximal,portion |
R1625 | T6208 | T6206 | prep | of,portion |
R1626 | T6209 | T6208 | pobj | Fog2,of |
R1627 | T6210 | T6211 | amod | longer,transcripts |
R1628 | T6211 | T6203 | dobj | transcripts,revealed |
R1629 | T6291 | T6289 | dobj | codon,introduces |
R1630 | T6212 | T6211 | prep | in,transcripts |
R1631 | T6213 | T6214 | det | the,mutant |
R1632 | T6292 | T6291 | compound | stop,codon |
R1633 | T6214 | T6212 | pobj | mutant,in |
R1634 | T6215 | T6214 | compound | lil,mutant |
R1635 | T6216 | T6211 | prep | than,transcripts |
R1636 | T6293 | T6294 | dep | that,generates |
R1637 | T6217 | T6216 | prep | in,than |
R1638 | T6218 | T6219 | det | the,type |
R1639 | T6219 | T6217 | pobj | type,in |
R1640 | T6294 | T6291 | relcl | generates,codon |
R1641 | T6220 | T6219 | amod | wild,type |
R1642 | T6221 | T6219 | punct | -,type |
R1643 | T6295 | T6296 | det | a,product |
R1644 | T6222 | T6211 | appos | embryos,transcripts |
R1645 | T6223 | T6224 | punct | (,Figure |
R1646 | T6224 | T6203 | parataxis | Figure,revealed |
R1647 | T6296 | T6294 | dobj | product,generates |
R1648 | T6225 | T6224 | nummod | 2A,Figure |
R1649 | T6226 | T6224 | punct | ),Figure |
R1650 | T6227 | T6203 | punct | .,revealed |
R1651 | T6229 | T6230 | nsubj | Sequencing,revealed |
R1652 | T6297 | T6298 | advmod | severely,truncated |
R1653 | T6231 | T6229 | prep | of,Sequencing |
R1654 | T6232 | T6233 | det | the,transcript |
R1655 | T6298 | T6296 | amod | truncated,product |
R1656 | T6233 | T6231 | pobj | transcript,of |
R1657 | T6234 | T6233 | compound | mutant,transcript |
R1658 | T6235 | T6236 | det | a,mutation |
R1659 | T6299 | T6296 | compound | protein,product |
R1660 | T6236 | T6230 | dobj | mutation,revealed |
R1661 | T6237 | T6236 | compound | point,mutation |
R1662 | T6238 | T6236 | punct | (,mutation |
R1663 | T6300 | T6301 | punct | (,Figure |
R1664 | T6239 | T6236 | prep | from,mutation |
R1665 | T6240 | T6239 | pobj | thymine,from |
R1666 | T6301 | T6289 | parataxis | Figure,introduces |
R1667 | T6241 | T6239 | prep | to,from |
R1668 | T6242 | T6241 | pobj | cytosine,to |
R1669 | T6243 | T6236 | punct | ),mutation |
R1670 | T6244 | T6245 | nummod | 2,bp |
R1671 | T6245 | T6246 | npadvmod | bp,after |
R1672 | T6246 | T6230 | prep | after,revealed |
R1673 | T6302 | T6301 | nummod | 2B,Figure |
R1674 | T6247 | T6246 | pobj | position,after |
R1675 | T6248 | T6247 | nummod | 301,position |
R1676 | T6303 | T6301 | punct | ),Figure |
R1677 | T6249 | T6247 | punct | ", ",position |
R1678 | T6250 | T6251 | dep | which,is |
R1679 | T6251 | T6247 | relcl | is,position |
R1680 | T6304 | T6268 | punct | .,causes |
R1681 | T6252 | T6251 | prep | in,is |
R1682 | T6253 | T6254 | det | the,site |
R1683 | T6254 | T6252 | pobj | site,in |
R1684 | T6306 | T6307 | amod | Heterozygous,mice |
R1685 | T6255 | T6254 | compound | splice,site |
R1686 | T6256 | T6254 | compound | donor,site |
R1687 | T6257 | T6254 | prep | at,site |
R1688 | T6258 | T6259 | det | the,end |
R1689 | T6259 | T6257 | pobj | end,at |
R1690 | T6307 | T6310 | nsubjpass | mice,crossed |
R1691 | T6260 | T6259 | prep | of,end |
R1692 | T6261 | T6262 | det | the,exon |
R1693 | T6262 | T6260 | pobj | exon,of |
R1694 | T6308 | T6309 | compound | lil,mutant |
R1695 | T6263 | T6262 | amod | third,exon |
R1696 | T6264 | T6230 | punct | .,revealed |
R1697 | T6309 | T6307 | compound | mutant,mice |
R1698 | T6266 | T6267 | det | This,mutation |
R1699 | T6267 | T6268 | nsubj | mutation,causes |
R1700 | T6311 | T6310 | auxpass | were,crossed |
R1701 | T6269 | T6270 | det | a,defect |
R1702 | T6270 | T6268 | dobj | defect,causes |
R1703 | T6271 | T6270 | compound | splicing,defect |
R1704 | T6272 | T6273 | dep | that,results |
R1705 | T6312 | T6310 | prep | with,crossed |
R1706 | T6273 | T6270 | relcl | results,defect |
R1707 | T6274 | T6273 | prep | in,results |
R1708 | T6313 | T6314 | det | a,mutant |
R1709 | T6275 | T6276 | det | the,insertion |
R1710 | T6276 | T6274 | pobj | insertion,in |
R1711 | T6277 | T6276 | prep | of,insertion |
R1712 | T6314 | T6312 | pobj | mutant,with |
R1713 | T6278 | T6279 | nummod | 85,bp |
R1714 | T6279 | T6277 | pobj | bp,of |
R1715 | T6315 | T6314 | nmod | Fog2,mutant |
R1716 | T6280 | T6279 | prep | of,bp |
R1717 | T6281 | T6282 | amod | intronic,sequence |
R1718 | T6316 | T6315 | punct | +,Fog2 |
R1719 | T6282 | T6280 | pobj | sequence,of |
R1720 | T6283 | T6276 | prep | into,insertion |
R1721 | T6284 | T6285 | det | the,transcript |
R1722 | T6285 | T6283 | pobj | transcript,into |
R1723 | T6286 | T6285 | compound | mutant,transcript |
R1724 | T6317 | T6315 | punct | /,Fog2 |
R1725 | T6287 | T6268 | punct | ", ",causes |
R1726 | T6288 | T6268 | cc | and,causes |
R1727 | T6289 | T6268 | conj | introduces,causes |
R1728 | T6318 | T6315 | punct | −,Fog2 |
R1729 | T6319 | T6320 | punct | (,allele |
R1730 | T6320 | T6314 | parataxis | allele,mutant |
R1731 | T6321 | T6320 | amod | null,allele |
R1732 | T6322 | T6320 | punct | ),allele |
R1733 | T6323 | T6314 | acl | generated,mutant |
R1734 | T6324 | T6323 | prep | by,generated |
R1735 | T6325 | T6326 | compound | gene,targeting |
R1736 | T6326 | T6324 | pobj | targeting,by |
R1737 | T6327 | T6328 | punct | [,16 |
R1738 | T6328 | T6310 | parataxis | 16,crossed |
R1739 | T6329 | T6328 | punct | ],16 |
R1740 | T6330 | T6310 | punct | .,crossed |
R1741 | T6332 | T6333 | advmod | Doubly,heterozygous |
R1742 | T6333 | T6334 | amod | heterozygous,mice |
R1743 | T6334 | T6335 | nsubj | mice,had |
R1744 | T6335 | T6336 | ccomp | had,proves |
R1745 | T6337 | T6338 | det | an,phenotype |
R1746 | T6338 | T6335 | dobj | phenotype,had |
R1747 | T6339 | T6338 | amod | embryonic,phenotype |
R1748 | T6340 | T6338 | amod | lethal,phenotype |
R1749 | T6341 | T6336 | punct | ;,proves |
R1750 | T6342 | T6343 | det | this,failure |
R1751 | T6343 | T6336 | nsubj | failure,proves |
R1752 | T6344 | T6345 | aux | to,complement |
R1753 | T6345 | T6343 | acl | complement,failure |
R1754 | T6346 | T6347 | mark | that,is |
R1755 | T6347 | T6336 | ccomp | is,proves |
R1756 | T6348 | T6347 | nsubj | lil,is |
R1757 | T6349 | T6350 | det | a,mutation |
R1758 | T6350 | T6347 | attr | mutation,is |
R1759 | T6351 | T6350 | prep | in,mutation |
R1760 | T6352 | T6351 | pobj | Fog2,in |
R1761 | T6353 | T6336 | punct | .,proves |
R1762 | T6355 | T6356 | det | The,phenotype |
R1763 | T6356 | T6358 | nsubj | phenotype,is |
R1764 | T6357 | T6356 | amod | variable,phenotype |
R1765 | T6359 | T6356 | prep | of,phenotype |
R1766 | T6360 | T6361 | compound | lil,mice |
R1767 | T6361 | T6359 | pobj | mice,of |
R1768 | T6362 | T6356 | punct | (,phenotype |
R1769 | T6363 | T6356 | amod | relative,phenotype |
R1770 | T6364 | T6363 | prep | to,relative |
R1771 | T6365 | T6364 | pobj | that,to |
R1772 | T6366 | T6365 | acl | found,that |
R1773 | T6367 | T6366 | prep | for,found |
R1774 | T6368 | T6369 | det | the,mutant |
R1775 | T6369 | T6367 | pobj | mutant,for |
R1776 | T6370 | T6369 | nmod | Fog2,mutant |
R1777 | T6371 | T6370 | amod | null,Fog2 |
R1778 | T6372 | T6358 | punct | ),is |
R1779 | T6373 | T6358 | advmod | likely,is |
R1780 | T6374 | T6358 | prep | due,is |
R1781 | T6375 | T6374 | pcomp | to,due |
R1782 | T6376 | T6377 | det | the,generation |
R1783 | T6377 | T6374 | pobj | generation,due |
R1784 | T6378 | T6377 | prep | of,generation |
R1785 | T6379 | T6380 | det | a,level |
R1786 | T6380 | T6378 | pobj | level,of |
R1787 | T6381 | T6380 | amod | low,level |
R1788 | T6382 | T6380 | prep | of,level |
R1789 | T6383 | T6384 | amod | normal,transcript |
R1790 | T6384 | T6382 | pobj | transcript,of |
R1791 | T6385 | T6377 | prep | despite,generation |
R1792 | T6386 | T6387 | det | the,presence |
R1793 | T6387 | T6385 | pobj | presence,despite |
R1794 | T6388 | T6387 | prep | of,presence |
R1795 | T6389 | T6390 | det | the,mutation |
R1796 | T6390 | T6388 | pobj | mutation,of |
R1797 | T6391 | T6392 | compound | splice,site |
R1798 | T6392 | T6390 | compound | site,mutation |
R1799 | T6393 | T6358 | punct | .,is |
R1805 | T8121 | T8122 | nmod | Lung,Development |
R1806 | T8123 | T8121 | cc | and,Lung |
R1807 | T8124 | T8121 | conj | Diaphragm,Lung |
R1808 | T8125 | T8122 | prep | in,Development |
R1809 | T8126 | T8127 | det | the,Mouse |
R1810 | T8127 | T8125 | pobj | Mouse,in |
R1811 | T8128 | T8129 | compound | Fog2,Mutant |
R1812 | T8129 | T8127 | compound | Mutant,Mouse |
R1813 | T8131 | T8132 | nsubjpass | Experiments,conducted |
R1814 | T8133 | T8132 | auxpass | were,conducted |
R1815 | T8134 | T8135 | aux | to,evaluate |
R1816 | T8135 | T8132 | advcl | evaluate,conducted |
R1817 | T8136 | T8137 | det | the,role |
R1818 | T8137 | T8135 | dobj | role,evaluate |
R1819 | T8138 | T8137 | prep | of,role |
R1820 | T8139 | T8138 | pobj | Fog2,of |
R1821 | T8140 | T8137 | prep | in,role |
R1822 | T8141 | T8142 | amod | pulmonary,development |
R1823 | T8142 | T8140 | pobj | development,in |
R1824 | T8143 | T8141 | cc | and,pulmonary |
R1825 | T8144 | T8141 | conj | diaphragmatic,pulmonary |
R1826 | T8145 | T8132 | punct | .,conducted |
R1827 | T8147 | T8148 | det | The,phenotype |
R1828 | T8148 | T8150 | nsubjpass | phenotype,characterized |
R1829 | T8149 | T8148 | amod | pulmonary,phenotype |
R1830 | T8151 | T8150 | auxpass | is,characterized |
R1831 | T8152 | T8150 | agent | by,characterized |
R1832 | T8153 | T8154 | amod | diffuse,hypoplasia |
R1833 | T8154 | T8152 | pobj | hypoplasia,by |
R1834 | T8155 | T8154 | cc | and,hypoplasia |
R1835 | T8156 | T8157 | amod | specific,loss |
R1836 | T8157 | T8154 | conj | loss,hypoplasia |
R1837 | T8158 | T8157 | prep | of,loss |
R1838 | T8159 | T8160 | det | the,lobe |
R1839 | T8160 | T8158 | pobj | lobe,of |
R1840 | T8161 | T8160 | amod | accessory,lobe |
R1841 | T8162 | T8160 | cc | and,lobe |
R1842 | T8163 | T8164 | det | a,portion |
R1843 | T8164 | T8160 | conj | portion,lobe |
R1844 | T8165 | T8164 | prep | of,portion |
R1845 | T8166 | T8167 | det | the,lobe |
R1846 | T8167 | T8165 | pobj | lobe,of |
R1847 | T8168 | T8167 | amod | right,lobe |
R1848 | T8169 | T8167 | amod | middle,lobe |
R1849 | T8170 | T8150 | punct | .,characterized |
R1850 | T8172 | T8173 | nsubj | It,is |
R1851 | T8174 | T8175 | advmod | well,established |
R1852 | T8175 | T8173 | acomp | established,is |
R1853 | T8176 | T8177 | mark | that,result |
R1854 | T8177 | T8173 | ccomp | result,is |
R1855 | T8178 | T8177 | nsubj | abnormalities,result |
R1856 | T8179 | T8178 | prep | in,abnormalities |
R1857 | T8180 | T8181 | preconj | either,development |
R1858 | T8181 | T8179 | pobj | development,in |
R1859 | T8182 | T8181 | amod | diaphragmatic,development |
R1860 | T8183 | T8181 | cc | or,development |
R1861 | T8184 | T8185 | amod | fetal,breathing |
R1862 | T8185 | T8181 | conj | breathing,development |
R1863 | T8186 | T8177 | aux | can,result |
R1864 | T8187 | T8177 | prep | in,result |
R1865 | T8188 | T8189 | det | a,hypoplasia |
R1866 | T8189 | T8187 | pobj | hypoplasia,in |
R1867 | T8190 | T8189 | amod | secondary,hypoplasia |
R1868 | T8191 | T8189 | amod | pulmonary,hypoplasia |
R1869 | T8192 | T8177 | punct | ", ",result |
R1870 | T8193 | T8194 | mark | although,documented |
R1871 | T8194 | T8177 | advcl | documented,result |
R1872 | T8195 | T8194 | nsubjpass | loss,documented |
R1873 | T8196 | T8195 | prep | of,loss |
R1874 | T8197 | T8198 | amod | normal,structure |
R1875 | T8198 | T8196 | pobj | structure,of |
R1876 | T8199 | T8194 | aux | has,documented |
R1877 | T8200 | T8194 | neg | never,documented |
R1878 | T8201 | T8194 | auxpass | been,documented |
R1879 | T8202 | T8194 | prep | in,documented |
R1880 | T8203 | T8204 | det | this,context |
R1881 | T8204 | T8202 | pobj | context,in |
R1882 | T8205 | T8206 | punct | [,18 |
R1883 | T8206 | T8173 | parataxis | 18,is |
R1884 | T8207 | T8206 | nummod | 17,18 |
R1885 | T8208 | T8206 | punct | ",",18 |
R1886 | T8209 | T8206 | punct | ],18 |
R1887 | T8210 | T8173 | punct | .,is |
R1888 | T8212 | T8213 | nsubjpass | Fog2,expressed |
R1889 | T8214 | T8213 | auxpass | is,expressed |
R1890 | T8215 | T8213 | advmod | diffusely,expressed |
R1891 | T8216 | T8213 | prep | in,expressed |
R1892 | T8217 | T8218 | det | the,mesenchyme |
R1893 | T8218 | T8216 | pobj | mesenchyme,in |
R1894 | T8219 | T8218 | amod | pulmonary,mesenchyme |
R1895 | T8220 | T8213 | prep | during,expressed |
R1896 | T8221 | T8222 | det | the,period |
R1897 | T8222 | T8220 | pobj | period,during |
R1898 | T8223 | T8222 | prep | of,period |
R1899 | T8224 | T8225 | compound | branching,morphogenesis |
R1900 | T8225 | T8223 | pobj | morphogenesis,of |
R1901 | T8226 | T8213 | punct | ", ",expressed |
R1902 | T8227 | T8228 | mark | while,restricted |
R1903 | T8228 | T8213 | advcl | restricted,expressed |
R1904 | T8229 | T8230 | amod | later,expression |
R1905 | T8230 | T8228 | nsubjpass | expression,restricted |
R1906 | T8231 | T8228 | auxpass | is,restricted |
R1907 | T8232 | T8228 | prep | to,restricted |
R1908 | T8233 | T8234 | det | the,muscles |
R1909 | T8234 | T8232 | pobj | muscles,to |
R1910 | T8235 | T8234 | amod | smooth,muscles |
R1911 | T8236 | T8234 | prep | of,muscles |
R1912 | T8237 | T8236 | pobj | airways,of |
R1913 | T8238 | T8237 | cc | and,airways |
R1914 | T8239 | T8240 | amod | pulmonary,vessels |
R1915 | T8240 | T8237 | conj | vessels,airways |
R1916 | T8241 | T8242 | punct | (,Figure |
R1917 | T8242 | T8213 | parataxis | Figure,expressed |
R1918 | T8243 | T8242 | nummod | 3,Figure |
R1919 | T8244 | T8242 | punct | ),Figure |
R1920 | T8245 | T8213 | punct | .,expressed |
R1921 | T8247 | T8248 | nsubj | This,suggests |
R1922 | T8249 | T8247 | punct | ", ",This |
R1923 | T8250 | T8247 | cc | and,This |
R1924 | T8251 | T8252 | det | the,observation |
R1925 | T8252 | T8247 | conj | observation,This |
R1926 | T8253 | T8254 | mark | that,appeared |
R1927 | T8254 | T8252 | acl | appeared,observation |
R1928 | T8255 | T8254 | nsubj | lungs,appeared |
R1929 | T8256 | T8254 | oprd | small,appeared |
R1930 | T8257 | T8254 | prep | on,appeared |
R1931 | T8258 | T8259 | amod | transverse,sections |
R1932 | T8259 | T8257 | pobj | sections,on |
R1933 | T8260 | T8259 | acl | evaluated,sections |
R1934 | T8261 | T8262 | amod | prior,to |
R1935 | T8262 | T8260 | prep | to,evaluated |
R1936 | T8263 | T8264 | amod | diaphragmatic,muscularization |
R1937 | T8264 | T8262 | pobj | muscularization,to |
R1938 | T8265 | T8264 | cc | or,muscularization |
R1939 | T8266 | T8264 | conj | function,muscularization |
R1940 | T8267 | T8248 | punct | ", ",suggests |
R1941 | T8268 | T8269 | mark | that,occurs |
R1942 | T8269 | T8248 | ccomp | occurs,suggests |
R1943 | T8270 | T8271 | det | the,hypoplasia |
R1944 | T8271 | T8269 | nsubj | hypoplasia,occurs |
R1945 | T8272 | T8271 | amod | pulmonary,hypoplasia |
R1946 | T8273 | T8269 | advmod | independently,occurs |
R1947 | T8274 | T8273 | prep | of,independently |
R1948 | T8275 | T8276 | det | the,defect |
R1949 | T8276 | T8274 | pobj | defect,of |
R1950 | T8277 | T8276 | amod | diaphragmatic,defect |
R1951 | T8278 | T8248 | punct | .,suggests |
R1952 | T8280 | T8281 | aux | To,test |
R1953 | T8281 | T8282 | advcl | test,dissected |
R1954 | T8283 | T8284 | det | this,hypothesis |
R1955 | T8284 | T8281 | dobj | hypothesis,test |
R1956 | T8285 | T8282 | punct | ", ",dissected |
R1957 | T8286 | T8282 | nsubjpass | lungs,dissected |
R1958 | T8287 | T8282 | auxpass | were,dissected |
R1959 | T8288 | T8282 | prep | from,dissected |
R1960 | T8289 | T8290 | nmod | Fog2,mice |
R1961 | T8290 | T8288 | pobj | mice,from |
R1962 | T8291 | T8289 | punct | −,Fog2 |
R1963 | T8292 | T8289 | punct | /,Fog2 |
R1964 | T8293 | T8289 | punct | −,Fog2 |
R1965 | T8294 | T8290 | cc | and,mice |
R1966 | T8295 | T8296 | compound | littermate,controls |
R1967 | T8296 | T8290 | conj | controls,mice |
R1968 | T8297 | T8282 | prep | before,dissected |
R1969 | T8298 | T8299 | det | the,onset |
R1970 | T8299 | T8297 | pobj | onset,before |
R1971 | T8300 | T8299 | prep | of,onset |
R1972 | T8301 | T8302 | amod | fetal,motion |
R1973 | T8302 | T8300 | pobj | motion,of |
R1974 | T8303 | T8302 | amod | diaphragmatic,motion |
R1975 | T8304 | T8282 | punct | .,dissected |
R1976 | T8306 | T8307 | nmod | Fog2,mice |
R1977 | T8307 | T8311 | nsubjpass | mice,used |
R1978 | T8308 | T8306 | punct | −,Fog2 |
R1979 | T8309 | T8306 | punct | /,Fog2 |
R1980 | T8310 | T8306 | punct | −,Fog2 |
R1981 | T8312 | T8311 | auxpass | were,used |
R1982 | T8313 | T8311 | prep | for,used |
R1983 | T8314 | T8315 | det | this,experiment |
R1984 | T8315 | T8313 | pobj | experiment,for |
R1985 | T8316 | T8311 | punct | ", ",used |
R1986 | T8317 | T8318 | mark | as,wanted |
R1987 | T8318 | T8311 | advcl | wanted,used |
R1988 | T8319 | T8318 | nsubj | we,wanted |
R1989 | T8320 | T8321 | aux | to,avoid |
R1990 | T8321 | T8318 | xcomp | avoid,wanted |
R1991 | T8322 | T8323 | amod | potential,variance |
R1992 | T8323 | T8321 | dobj | variance,avoid |
R1993 | T8324 | T8323 | amod | phenotypic,variance |
R1994 | T8325 | T8323 | prep | from,variance |
R1995 | T8326 | T8327 | det | the,mutation |
R1996 | T8327 | T8325 | pobj | mutation,from |
R1997 | T8328 | T8327 | nmod | lil,mutation |
R1998 | T8329 | T8327 | amod | hypomorphic,mutation |
R1999 | T8330 | T8311 | punct | .,used |
R2000 | T8332 | T8333 | nsubj | Lungs,were |
R2001 | T8334 | T8332 | acl | dissected,Lungs |
R2002 | T8335 | T8334 | prep | at,dissected |
R2003 | T8336 | T8335 | pobj | E12,at |
R2004 | T8337 | T8332 | prep | from,Lungs |
R2005 | T8338 | T8339 | nmod | Fog2,embryos |
R2006 | T8339 | T8337 | pobj | embryos,from |
R2007 | T8340 | T8338 | punct | −,Fog2 |
R2008 | T8341 | T8338 | punct | /,Fog2 |
R2009 | T8342 | T8338 | punct | −,Fog2 |
R2010 | T8343 | T8333 | acomp | smaller,were |
R2011 | T8344 | T8343 | prep | in,smaller |
R2012 | T8345 | T8344 | pobj | size,in |
R2013 | T8346 | T8333 | cc | and,were |
R2014 | T8347 | T8333 | conj | lacked,were |
R2015 | T8348 | T8349 | det | the,development |
R2016 | T8349 | T8347 | dobj | development,lacked |
R2017 | T8350 | T8349 | prep | of,development |
R2018 | T8351 | T8352 | det | an,lobe |
R2019 | T8352 | T8350 | pobj | lobe,of |
R2020 | T8353 | T8352 | amod | accessory,lobe |
R2021 | T8354 | T8333 | punct | .,were |
R2022 | T8356 | T8357 | prep | In,was |
R2023 | T8358 | T8359 | nummod | 11,explants |
R2024 | T8359 | T8356 | pobj | explants,In |
R2025 | T8360 | T8359 | amod | viable,explants |
R2026 | T8361 | T8359 | nmod | Fog2,explants |
R2027 | T8362 | T8361 | punct | −,Fog2 |
R2028 | T8363 | T8361 | punct | /,Fog2 |
R2029 | T8364 | T8361 | punct | −,Fog2 |
R2030 | T8365 | T8366 | compound | lung,culture |
R2031 | T8366 | T8359 | compound | culture,explants |
R2032 | T8367 | T8357 | punct | ", ",was |
R2033 | T8368 | T8357 | expl | there,was |
R2034 | T8369 | T8357 | neg | never,was |
R2035 | T8370 | T8357 | attr | development,was |
R2036 | T8371 | T8370 | prep | of,development |
R2037 | T8372 | T8373 | det | an,lobe |
R2038 | T8373 | T8371 | pobj | lobe,of |
R2039 | T8374 | T8373 | amod | accessory,lobe |
R2040 | T8375 | T8357 | punct | ", ",was |
R2041 | T8376 | T8357 | cc | and,was |
R2042 | T8377 | T8378 | det | the,weights |
R2043 | T8378 | T8379 | nsubj | weights,were |
R2044 | T8379 | T8357 | conj | were,was |
R2045 | T8380 | T8378 | prep | of,weights |
R2046 | T8381 | T8382 | compound | mutant,lungs |
R2047 | T8382 | T8380 | pobj | lungs,of |
R2048 | T8383 | T8382 | acl | cultured,lungs |
R2049 | T8384 | T8383 | prep | for,cultured |
R2050 | T8385 | T8386 | nummod | 5,d |
R2051 | T8386 | T8384 | pobj | d,for |
R2052 | T8387 | T8388 | advmod | significantly,lower |
R2053 | T8388 | T8379 | acomp | lower,were |
R2054 | T8389 | T8388 | prep | than,lower |
R2055 | T8390 | T8389 | pobj | those,than |
R2056 | T8391 | T8390 | prep | of,those |
R2057 | T8392 | T8393 | compound | littermate,controls |
R2058 | T8393 | T8391 | pobj | controls,of |
R2059 | T8394 | T8395 | punct | (,Figure |
R2060 | T8395 | T8379 | parataxis | Figure,were |
R2061 | T8396 | T8395 | nummod | 4,Figure |
R2062 | T8397 | T8395 | punct | ),Figure |
R2063 | T8398 | T8357 | punct | .,was |
R2064 | T8400 | T8401 | det | These,data |
R2065 | T8401 | T8402 | nsubj | data,demonstrate |
R2066 | T8403 | T8404 | mark | that,is |
R2067 | T8404 | T8402 | ccomp | is,demonstrate |
R2068 | T8405 | T8406 | det | the,hypoplasia |
R2069 | T8406 | T8404 | nsubj | hypoplasia,is |
R2070 | T8407 | T8406 | amod | pulmonary,hypoplasia |
R2071 | T8408 | T8406 | prep | in,hypoplasia |
R2072 | T8409 | T8410 | compound | Fog2,mice |
R2073 | T8410 | T8408 | pobj | mice,in |
R2074 | T8411 | T8410 | compound | mutant,mice |
R2075 | T8412 | T8413 | det | a,defect |
R2076 | T8413 | T8404 | attr | defect,is |
R2077 | T8414 | T8413 | amod | primary,defect |
R2078 | T8415 | T8402 | punct | .,demonstrate |
R2079 | T8417 | T8418 | nsubj | Branching,appeared |
R2080 | T8419 | T8417 | prep | in,Branching |
R2081 | T8420 | T8421 | det | the,lobes |
R2082 | T8421 | T8419 | pobj | lobes,in |
R2083 | T8422 | T8421 | amod | unaffected,lobes |
R2084 | T8423 | T8424 | aux | to,delayed |
R2085 | T8424 | T8418 | xcomp | delayed,appeared |
R2086 | T8425 | T8424 | auxpass | be,delayed |
R2087 | T8426 | T8424 | prep | by,delayed |
R2088 | T8427 | T8428 | quantmod | 6,12 |
R2089 | T8428 | T8430 | nummod | 12,h |
R2090 | T8429 | T8428 | punct | –,12 |
R2091 | T8430 | T8426 | pobj | h,by |
R2092 | T8431 | T8418 | punct | ", ",appeared |
R2093 | T8432 | T8418 | cc | but,appeared |
R2094 | T8433 | T8434 | det | all,mutants |
R2095 | T8434 | T8435 | nsubj | mutants,developed |
R2096 | T8435 | T8418 | conj | developed,appeared |
R2097 | T8436 | T8437 | det | an,pattern |
R2098 | T8437 | T8435 | dobj | pattern,developed |
R2099 | T8438 | T8437 | amod | intricate,pattern |
R2100 | T8439 | T8437 | compound | branching,pattern |
R2101 | T8440 | T8435 | prep | in,developed |
R2102 | T8441 | T8442 | det | the,lobes |
R2103 | T8442 | T8440 | pobj | lobes,in |
R2104 | T8443 | T8442 | amod | unaffected,lobes |
R2105 | T8444 | T8435 | prep | after,developed |
R2106 | T8445 | T8444 | pobj | culture,after |
R2107 | T8446 | T8445 | prep | for,culture |
R2108 | T8447 | T8448 | nummod | 5,d |
R2109 | T8448 | T8446 | pobj | d,for |
R2110 | T8449 | T8435 | punct | .,developed |
R2111 | T8451 | T8452 | mark | Because,is |
R2112 | T8452 | T8456 | advcl | is,evaluated |
R2113 | T8453 | T8454 | det | the,phenotype |
R2114 | T8454 | T8452 | nsubj | phenotype,is |
R2115 | T8455 | T8454 | compound | Fog2,phenotype |
R2116 | T8457 | T8452 | acomp | striking,is |
R2117 | T8458 | T8457 | prep | for,striking |
R2118 | T8459 | T8460 | amod | specific,loss |
R2119 | T8460 | T8458 | pobj | loss,for |
R2120 | T8461 | T8460 | compound | lobar,loss |
R2121 | T8462 | T8456 | punct | ", ",evaluated |
R2122 | T8463 | T8464 | det | the,pattern |
R2123 | T8464 | T8456 | nsubjpass | pattern,evaluated |
R2124 | T8465 | T8464 | amod | spatial,pattern |
R2125 | T8466 | T8464 | prep | of,pattern |
R2126 | T8467 | T8468 | compound | Fog2,expression |
R2127 | T8468 | T8466 | pobj | expression,of |
R2128 | T8469 | T8456 | auxpass | was,evaluated |
R2129 | T8470 | T8456 | prep | in,evaluated |
R2130 | T8471 | T8472 | amod | normal,embryos |
R2131 | T8472 | T8470 | pobj | embryos,in |
R2132 | T8473 | T8456 | prep | during,evaluated |
R2133 | T8474 | T8475 | det | the,period |
R2134 | T8475 | T8473 | pobj | period,during |
R2135 | T8476 | T8475 | prep | of,period |
R2136 | T8477 | T8478 | amod | early,establishment |
R2137 | T8478 | T8476 | pobj | establishment,of |
R2138 | T8479 | T8478 | compound | lobar,establishment |
R2139 | T8480 | T8481 | aux | to,determine |
R2140 | T8481 | T8456 | advcl | determine,evaluated |
R2141 | T8482 | T8483 | mark | whether,is |
R2142 | T8483 | T8481 | ccomp | is,determine |
R2143 | T8484 | T8485 | compound | Fog2,expression |
R2144 | T8485 | T8483 | nsubj | expression,is |
R2145 | T8486 | T8487 | advmod | specifically,different |
R2146 | T8487 | T8483 | acomp | different,is |
R2147 | T8488 | T8483 | prep | at,is |
R2148 | T8489 | T8490 | det | these,buds |
R2149 | T8490 | T8488 | pobj | buds,at |
R2150 | T8491 | T8490 | compound | lobar,buds |
R2151 | T8492 | T8456 | punct | .,evaluated |
R2152 | T8494 | T8495 | nsubjpass | Expression,evaluated |
R2153 | T8496 | T8495 | auxpass | was,evaluated |
R2154 | T8497 | T8495 | prep | in,evaluated |
R2155 | T8498 | T8497 | pobj | mice,in |
R2156 | T8499 | T8498 | acl | carrying,mice |
R2157 | T8500 | T8501 | det | a,gene |
R2158 | T8501 | T8499 | dobj | gene,carrying |
R2159 | T8502 | T8501 | compound | lacZ,gene |
R2160 | T8503 | T8501 | acl | incorporated,gene |
R2161 | T8504 | T8503 | prep | into,incorporated |
R2162 | T8505 | T8506 | det | the,locus |
R2163 | T8506 | T8504 | pobj | locus,into |
R2164 | T8507 | T8506 | compound | Fog2,locus |
R2165 | T8508 | T8509 | punct | (,S. |
R2166 | T8509 | T8495 | meta | S.,evaluated |
R2167 | T8510 | T8509 | nmod | Tevosian,S. |
R2168 | T8511 | T8509 | punct | ", ",S. |
R2169 | T8512 | T8509 | amod | unpublished,S. |
R2170 | T8513 | T8509 | nmod | data,S. |
R2171 | T8514 | T8509 | punct | ),S. |
R2172 | T8515 | T8495 | punct | .,evaluated |
R2173 | T8517 | T8518 | prep | In,showed |
R2174 | T8519 | T8520 | nummod | nine,mice |
R2175 | T8520 | T8517 | pobj | mice,In |
R2176 | T8521 | T8520 | acl | examined,mice |
R2177 | T8522 | T8521 | prep | at,examined |
R2178 | T8523 | T8522 | pobj | E11.5,at |
R2179 | T8524 | T8518 | punct | ", ",showed |
R2180 | T8525 | T8526 | det | all,lungs |
R2181 | T8526 | T8518 | nsubj | lungs,showed |
R2182 | T8527 | T8528 | det | a,enhancement |
R2183 | T8528 | T8518 | dobj | enhancement,showed |
R2184 | T8529 | T8528 | amod | specific,enhancement |
R2185 | T8530 | T8528 | prep | of,enhancement |
R2186 | T8531 | T8532 | compound | Fog2,expression |
R2187 | T8532 | T8530 | pobj | expression,of |
R2188 | T8533 | T8518 | prep | in,showed |
R2189 | T8534 | T8535 | det | the,mesenchyme |
R2190 | T8535 | T8533 | pobj | mesenchyme,in |
R2191 | T8536 | T8535 | acl | surrounding,mesenchyme |
R2192 | T8537 | T8538 | det | the,bud |
R2193 | T8538 | T8536 | dobj | bud,surrounding |
R2194 | T8539 | T8538 | amod | accessory,bud |
R2195 | T8540 | T8538 | cc | and,bud |
R2196 | T8541 | T8542 | det | the,bud |
R2197 | T8542 | T8538 | conj | bud,bud |
R2198 | T8543 | T8542 | amod | right,bud |
R2199 | T8544 | T8542 | amod | middle,bud |
R2200 | T8545 | T8542 | compound | lobe,bud |
R2201 | T8546 | T8538 | punct | ", ",bud |
R2202 | T8547 | T8548 | dep | which,are |
R2203 | T8548 | T8538 | relcl | are,bud |
R2204 | T8549 | T8550 | det | the,lobes |
R2205 | T8550 | T8548 | attr | lobes,are |
R2206 | T8551 | T8552 | dep | that,develop |
R2207 | T8552 | T8550 | relcl | develop,lobes |
R2208 | T8553 | T8552 | aux | do,develop |
R2209 | T8554 | T8552 | neg | not,develop |
R2210 | T8555 | T8552 | advmod | normally,develop |
R2211 | T8556 | T8552 | prep | in,develop |
R2212 | T8557 | T8558 | compound | Fog2,mice |
R2213 | T8558 | T8556 | pobj | mice,in |
R2214 | T8559 | T8558 | compound | mutant,mice |
R2215 | T8560 | T8561 | punct | (,Figure |
R2216 | T8561 | T8518 | parataxis | Figure,showed |
R2217 | T8562 | T8561 | nummod | 5,Figure |
R2218 | T8563 | T8561 | punct | ),Figure |
R2219 | T8564 | T8518 | punct | .,showed |
R2220 | T8566 | T8567 | prep | By,was |
R2221 | T8568 | T8566 | pobj | E12.5,By |
R2222 | T8569 | T8567 | punct | ", ",was |
R2223 | T8570 | T8567 | nsubj | expression,was |
R2224 | T8571 | T8567 | acomp | diffuse,was |
R2225 | T8572 | T8567 | prep | in,was |
R2226 | T8573 | T8574 | det | the,mesenchyme |
R2227 | T8574 | T8572 | pobj | mesenchyme,in |
R2228 | T8575 | T8574 | amod | pulmonary,mesenchyme |
R2229 | T8576 | T8567 | punct | ", ",was |
R2230 | T8577 | T8578 | mark | as,seen |
R2231 | T8578 | T8567 | advcl | seen,was |
R2232 | T8579 | T8578 | auxpass | was,seen |
R2233 | T8580 | T8578 | advmod | previously,seen |
R2234 | T8581 | T8578 | prep | with,seen |
R2235 | T8582 | T8583 | advmod | in,situ |
R2236 | T8583 | T8584 | amod | situ,hybridization |
R2237 | T8584 | T8581 | pobj | hybridization,with |
R2238 | T8585 | T8584 | prep | on,hybridization |
R2239 | T8586 | T8587 | compound | tissue,sections |
R2240 | T8587 | T8585 | pobj | sections,on |
R2241 | T8588 | T8567 | punct | .,was |
R2242 | T8590 | T8591 | nsubj | Diaphragms,show |
R2243 | T8592 | T8590 | prep | from,Diaphragms |
R2244 | T8593 | T8594 | compound | Fog2,mice |
R2245 | T8594 | T8592 | pobj | mice,from |
R2246 | T8595 | T8594 | compound | lil,mice |
R2247 | T8596 | T8597 | det | an,membrane |
R2248 | T8597 | T8591 | dobj | membrane,show |
R2249 | T8598 | T8597 | amod | intact,membrane |
R2250 | T8599 | T8597 | prep | with,membrane |
R2251 | T8600 | T8601 | det | a,defect |
R2252 | T8601 | T8599 | pobj | defect,with |
R2253 | T8602 | T8601 | prep | in,defect |
R2254 | T8603 | T8604 | amod | muscular,patterning |
R2255 | T8604 | T8602 | pobj | patterning,in |
R2256 | T8605 | T8606 | punct | (,see |
R2257 | T8606 | T8591 | parataxis | see,show |
R2258 | T8607 | T8606 | dobj | Figure,see |
R2259 | T8608 | T8607 | nummod | 1B,Figure |
R2260 | T8609 | T8606 | punct | ),see |
R2261 | T8610 | T8591 | punct | .,show |
R2262 | T8612 | T8613 | det | The,portion |
R2263 | T8613 | T8615 | nsubjpass | portion,populated |
R2264 | T8614 | T8613 | amod | membranous,portion |
R2265 | T8658 | T8656 | cc | but,intact |
R2266 | T8659 | T8656 | conj | amuscular,intact |
R2267 | T8616 | T8613 | prep | of,portion |
R2268 | T8660 | T8661 | punct | [,22 |
R2269 | T8661 | T8641 | parataxis | 22,have |
R2270 | T8662 | T8661 | nummod | 17,22 |
R2271 | T8617 | T8618 | det | the,diaphragm |
R2272 | T8663 | T8661 | punct | ",",22 |
R2273 | T8664 | T8661 | nummod | 21,22 |
R2274 | T8665 | T8661 | punct | ",",22 |
R2275 | T8618 | T8616 | pobj | diaphragm,of |
R2276 | T8666 | T8661 | punct | ],22 |
R2277 | T8667 | T8641 | punct | .,have |
R2278 | T8619 | T8615 | auxpass | is,populated |
R2279 | T8669 | T8670 | compound | Hepatocyte,factor |
R2280 | T8670 | T8672 | nsubj | factor,is |
R2281 | T8620 | T8615 | agent | by,populated |
R2282 | T8671 | T8670 | compound | growth,factor |
R2283 | T8673 | T8670 | punct | /,factor |
R2284 | T8621 | T8622 | det | a,population |
R2285 | T8674 | T8675 | compound | Scatter,factor |
R2286 | T8675 | T8670 | appos | factor,factor |
R2287 | T8676 | T8670 | punct | (,factor |
R2288 | T8622 | T8620 | pobj | population,by |
R2289 | T8677 | T8670 | appos | HGF,factor |
R2290 | T8678 | T8672 | punct | ),is |
R2291 | T8679 | T8680 | nummod | one,candidate |
R2292 | T8623 | T8622 | amod | migratory,population |
R2293 | T8680 | T8672 | attr | candidate,is |
R2294 | T8681 | T8680 | amod | potential,candidate |
R2295 | T8624 | T8622 | prep | of,population |
R2296 | T8682 | T8680 | amod | responsible,candidate |
R2297 | T8683 | T8682 | prep | for,responsible |
R2298 | T8684 | T8685 | det | the,guidance |
R2299 | T8625 | T8626 | compound | muscle,cells |
R2300 | T8685 | T8683 | pobj | guidance,for |
R2301 | T8686 | T8685 | prep | of,guidance |
R2302 | T8687 | T8688 | compound | muscle,precursors |
R2303 | T8626 | T8624 | pobj | cells,of |
R2304 | T8688 | T8686 | pobj | precursors,of |
R2305 | T8689 | T8688 | prep | to,precursors |
R2306 | T8627 | T8626 | compound | precursor,cells |
R2307 | T8690 | T8691 | det | the,diaphragm |
R2308 | T8691 | T8689 | pobj | diaphragm,to |
R2309 | T8692 | T8691 | amod | membranous,diaphragm |
R2310 | T8628 | T8615 | punct | ", ",populated |
R2311 | T8693 | T8672 | punct | .,is |
R2312 | T8629 | T8630 | advmod | much,like |
R2313 | T8695 | T8696 | nsubjpass | It,shown |
R2314 | T8697 | T8696 | aux | has,shown |
R2315 | T8630 | T8615 | prep | like,populated |
R2316 | T8698 | T8696 | auxpass | been,shown |
R2317 | T8631 | T8632 | det | the,limbs |
R2318 | T8699 | T8700 | mark | that,expressed |
R2319 | T8700 | T8696 | ccomp | expressed,shown |
R2320 | T8701 | T8700 | nsubjpass | HGF,expressed |
R2321 | T8702 | T8700 | auxpass | is,expressed |
R2322 | T8632 | T8630 | pobj | limbs,like |
R2323 | T8703 | T8700 | prep | along,expressed |
R2324 | T8704 | T8705 | det | this,pathway |
R2325 | T8633 | T8634 | punct | [,20 |
R2326 | T8705 | T8703 | pobj | pathway,along |
R2327 | T8706 | T8705 | amod | anatomic,pathway |
R2328 | T8707 | T8708 | punct | [,23 |
R2329 | T8634 | T8615 | parataxis | 20,populated |
R2330 | T8708 | T8696 | parataxis | 23,shown |
R2331 | T8709 | T8708 | punct | ],23 |
R2332 | T8635 | T8634 | nummod | 19,20 |
R2333 | T8710 | T8696 | punct | ", ",shown |
R2334 | T8711 | T8696 | cc | and,shown |
R2335 | T8712 | T8713 | nsubj | mice,fail |
R2336 | T8636 | T8634 | punct | ",",20 |
R2337 | T8713 | T8696 | conj | fail,shown |
R2338 | T8714 | T8712 | prep | with,mice |
R2339 | T8637 | T8634 | punct | ],20 |
R2340 | T8715 | T8714 | pobj | absence,with |
R2341 | T8716 | T8715 | prep | of,absence |
R2342 | T8717 | T8718 | det | the,receptor |
R2343 | T8638 | T8615 | punct | .,populated |
R2344 | T8718 | T8716 | pobj | receptor,of |
R2345 | T8719 | T8718 | compound | HGF,receptor |
R2346 | T8720 | T8721 | compound | c,Met |
R2347 | T8640 | T8641 | nsubj | Mice,have |
R2348 | T8721 | T8718 | appos | Met,receptor |
R2349 | T8722 | T8721 | punct | -,Met |
R2350 | T8723 | T8724 | aux | to,form |
R2351 | T8724 | T8713 | xcomp | form,fail |
R2352 | T8725 | T8726 | amod | muscularized,folds |
R2353 | T8642 | T8640 | prep | with,Mice |
R2354 | T8726 | T8724 | dobj | folds,form |
R2355 | T8727 | T8726 | amod | pleuroperitoneal,folds |
R2356 | T8728 | T8726 | punct | (,folds |
R2357 | T8729 | T8726 | appos | PPFs,folds |
R2358 | T8643 | T8642 | pobj | defects,with |
R2359 | T8730 | T8713 | punct | ),fail |
R2360 | T8644 | T8643 | prep | in,defects |
R2361 | T8731 | T8713 | punct | ", ",fail |
R2362 | T8732 | T8713 | cc | and,fail |
R2363 | T8733 | T8734 | advmod | thus,have |
R2364 | T8645 | T8644 | pobj | genes,in |
R2365 | T8734 | T8713 | conj | have,fail |
R2366 | T8735 | T8736 | amod | amuscular,diaphragms |
R2367 | T8736 | T8734 | dobj | diaphragms,have |
R2368 | T8646 | T8645 | acl | known,genes |
R2369 | T8737 | T8738 | punct | [,25 |
R2370 | T8738 | T8734 | parataxis | 25,have |
R2371 | T8739 | T8738 | nummod | 24,25 |
R2372 | T8740 | T8738 | punct | ",",25 |
R2373 | T8741 | T8738 | punct | ],25 |
R2374 | T8742 | T8713 | punct | .,fail |
R2375 | T8647 | T8648 | aux | to,be |
R2376 | T8744 | T8745 | nsubjpass | Fog2,expressed |
R2377 | T8746 | T8745 | auxpass | is,expressed |
R2378 | T8648 | T8646 | xcomp | be,known |
R2379 | T8747 | T8745 | advmod | diffusely,expressed |
R2380 | T8748 | T8745 | prep | in,expressed |
R2381 | T8649 | T8648 | acomp | important,be |
R2382 | T8650 | T8649 | prep | for,important |
R2383 | T8749 | T8750 | det | the,diaphragm |
R2384 | T8651 | T8652 | det | the,control |
R2385 | T8750 | T8748 | pobj | diaphragm,in |
R2386 | T8751 | T8750 | amod | early,diaphragm |
R2387 | T8652 | T8650 | pobj | control,for |
R2388 | T8752 | T8750 | amod | amuscular,diaphragm |
R2389 | T8753 | T8750 | prep | at,diaphragm |
R2390 | T8653 | T8652 | prep | of,control |
R2391 | T8754 | T8753 | pobj | E11.5,at |
R2392 | T8755 | T8756 | advmod | as,as |
R2393 | T8756 | T8748 | cc | as,in |
R2394 | T8654 | T8655 | det | this,process |
R2395 | T8757 | T8756 | advmod | well,as |
R2396 | T8758 | T8748 | conj | in,in |
R2397 | T8759 | T8760 | det | the,diaphragm |
R2398 | T8655 | T8653 | pobj | process,of |
R2399 | T8760 | T8758 | pobj | diaphragm,in |
R2400 | T8761 | T8760 | amod | later,diaphragm |
R2401 | T8762 | T8760 | amod | muscularized,diaphragm |
R2402 | T8656 | T8657 | amod | intact,diaphragms |
R2403 | T8657 | T8641 | dobj | diaphragms,have |
R2404 | T8869 | T8867 | pobj | path,along |
R2405 | T8763 | T8764 | punct | (,see |
R2406 | T8870 | T8869 | prep | of,path |
R2407 | T8764 | T8745 | parataxis | see,expressed |
R2408 | T8765 | T8766 | nmod | Figure,3C |
R2409 | T8871 | T8872 | compound | muscle,cell |
R2410 | T8766 | T8764 | dobj | 3C,see |
R2411 | T8767 | T8766 | cc | and,3C |
R2412 | T8768 | T8766 | conj | 3D,3C |
R2413 | T8872 | T8874 | compound | cell,migration |
R2414 | T8769 | T8764 | punct | ),see |
R2415 | T8770 | T8745 | punct | .,expressed |
R2416 | T8873 | T8872 | compound | precursor,cell |
R2417 | T8772 | T8773 | nsubjpass | Pax3,detected |
R2418 | T8874 | T8870 | pobj | migration,of |
R2419 | T8774 | T8772 | cc | and,Pax3 |
R2420 | T8775 | T8772 | conj | MyoD,Pax3 |
R2421 | T8776 | T8772 | punct | ", ",Pax3 |
R2422 | T8777 | T8778 | compound | transcription,factors |
R2423 | T8778 | T8772 | appos | factors,Pax3 |
R2424 | T8779 | T8778 | acl | required,factors |
R2425 | T8875 | T8869 | prep | between,path |
R2426 | T8780 | T8779 | prep | for,required |
R2427 | T8781 | T8782 | amod | appropriate,migration |
R2428 | T8782 | T8780 | pobj | migration,for |
R2429 | T8783 | T8782 | cc | and,migration |
R2430 | T8876 | T8877 | det | the,PPF |
R2431 | T8877 | T8875 | pobj | PPF,between |
R2432 | T8784 | T8782 | conj | determination,migration |
R2433 | T8878 | T8877 | cc | and,PPF |
R2434 | T8785 | T8782 | prep | of,migration |
R2435 | T8786 | T8787 | amod | myogenic,precursors |
R2436 | T8787 | T8785 | pobj | precursors,of |
R2437 | T8879 | T8880 | det | the,diaphragm |
R2438 | T8788 | T8773 | punct | ", ",detected |
R2439 | T8789 | T8773 | auxpass | were,detected |
R2440 | T8790 | T8773 | prep | in,detected |
R2441 | T8880 | T8877 | conj | diaphragm,PPF |
R2442 | T8791 | T8792 | det | the,PPFs |
R2443 | T8792 | T8790 | pobj | PPFs,in |
R2444 | T8881 | T8863 | prep | for,accounts |
R2445 | T8793 | T8792 | prep | of,PPFs |
R2446 | T8794 | T8795 | compound | Fog2,mice |
R2447 | T8795 | T8793 | pobj | mice,of |
R2448 | T8796 | T8795 | compound | lil,mice |
R2449 | T8882 | T8883 | det | the,phenotype |
R2450 | T8797 | T8798 | punct | (,shown |
R2451 | T8798 | T8773 | parataxis | shown,detected |
R2452 | T8799 | T8798 | nsubj | data,shown |
R2453 | T8883 | T8881 | pobj | phenotype,for |
R2454 | T8800 | T8798 | neg | not,shown |
R2455 | T8801 | T8798 | punct | ),shown |
R2456 | T8884 | T8883 | amod | abnormal,phenotype |
R2457 | T8802 | T8773 | punct | .,detected |
R2458 | T8804 | T8805 | advmod | However,demonstrated |
R2459 | T8885 | T8863 | prep | in,accounts |
R2460 | T8806 | T8805 | punct | ", ",demonstrated |
R2461 | T8807 | T8808 | advmod | in,situ |
R2462 | T8886 | T8887 | det | these,mice |
R2463 | T8808 | T8809 | amod | situ,analysis |
R2464 | T8809 | T8805 | nsubj | analysis,demonstrated |
R2465 | T8810 | T8809 | compound | expression,analysis |
R2466 | T8887 | T8885 | pobj | mice,in |
R2467 | T8811 | T8812 | mark | that,reduced |
R2468 | T8812 | T8805 | ccomp | reduced,demonstrated |
R2469 | T8813 | T8814 | det | the,expression |
R2470 | T8888 | T8863 | punct | .,accounts |
R2471 | T8814 | T8812 | nsubjpass | expression,reduced |
R2472 | T8815 | T8814 | prep | of,expression |
R2473 | T8816 | T8815 | pobj | HGF,of |
R2474 | T8817 | T8814 | prep | in,expression |
R2475 | T8818 | T8819 | det | the,region |
R2476 | T8819 | T8817 | pobj | region,in |
R2477 | T8820 | T8821 | advmod | where,meets |
R2478 | T8821 | T8819 | relcl | meets,region |
R2479 | T8822 | T8823 | det | this,structure |
R2480 | T8823 | T8821 | nsubj | structure,meets |
R2481 | T8824 | T8825 | det | the,diaphragm |
R2482 | T8825 | T8821 | dobj | diaphragm,meets |
R2483 | T8826 | T8825 | amod | membranous,diaphragm |
R2484 | T8827 | T8812 | auxpass | was,reduced |
R2485 | T8828 | T8812 | advmod | markedly,reduced |
R2486 | T8829 | T8812 | prep | in,reduced |
R2487 | T8830 | T8831 | compound | Fog2,mice |
R2488 | T8831 | T8829 | pobj | mice,in |
R2489 | T8832 | T8831 | compound | mutant,mice |
R2490 | T8833 | T8834 | punct | (,Figure |
R2491 | T8834 | T8805 | parataxis | Figure,demonstrated |
R2492 | T8835 | T8834 | nummod | 6,Figure |
R2493 | T8836 | T8834 | punct | ),Figure |
R2494 | T8837 | T8805 | punct | .,demonstrated |
R2495 | T8839 | T8840 | nsubj | We,hypothesize |
R2496 | T8841 | T8842 | mark | that,required |
R2497 | T8842 | T8840 | ccomp | required,hypothesize |
R2498 | T8843 | T8842 | nsubjpass | Fog2,required |
R2499 | T8844 | T8842 | auxpass | is,required |
R2500 | T8845 | T8842 | punct | (,required |
R2501 | T8846 | T8847 | preconj | either,directly |
R2502 | T8847 | T8842 | advmod | directly,required |
R2503 | T8848 | T8847 | cc | or,directly |
R2504 | T8849 | T8847 | conj | indirectly,directly |
R2505 | T8850 | T8842 | punct | ),required |
R2506 | T8851 | T8842 | prep | for,required |
R2507 | T8852 | T8853 | det | the,induction |
R2508 | T8853 | T8851 | pobj | induction,for |
R2509 | T8854 | T8853 | prep | of,induction |
R2510 | T8855 | T8854 | pobj | HGF,of |
R2511 | T8856 | T8853 | prep | in,induction |
R2512 | T8857 | T8858 | det | the,diaphragm |
R2513 | T8858 | T8856 | pobj | diaphragm,in |
R2514 | T8859 | T8858 | amod | developing,diaphragm |
R2515 | T8860 | T8840 | punct | ", ",hypothesize |
R2516 | T8861 | T8840 | cc | and,hypothesize |
R2517 | T8862 | T8863 | nsubj | dysregulation,accounts |
R2518 | T8863 | T8840 | conj | accounts,hypothesize |
R2519 | T8864 | T8862 | prep | of,dysregulation |
R2520 | T8865 | T8866 | compound | HGF,patterning |
R2521 | T8866 | T8864 | pobj | patterning,of |
R2522 | T8867 | T8866 | prep | along,patterning |
R2523 | T8868 | T8869 | det | the,path |
R2526 | T9907 | T9908 | compound | FOG2,Mutation |
R2527 | T9909 | T9908 | prep | in,Mutation |
R2528 | T9910 | T9911 | det | a,Patient |
R2529 | T9911 | T9909 | pobj | Patient,in |
R2530 | T9912 | T9911 | prep | with,Patient |
R2531 | T9913 | T9914 | nmod | Diaphragm,Abnormalities |
R2532 | T9914 | T9912 | pobj | Abnormalities,with |
R2533 | T9915 | T9913 | cc | and,Diaphragm |
R2534 | T9916 | T9913 | conj | Lung,Diaphragm |
R2535 | T9918 | T9919 | compound | FOG2,analysis |
R2536 | T9919 | T9921 | nsubjpass | analysis,performed |
R2537 | T9920 | T9919 | compound | sequence,analysis |
R2538 | T9922 | T9921 | auxpass | was,performed |
R2539 | T9923 | T9921 | prep | on,performed |
R2540 | T9924 | T9925 | compound | autopsy,tissue |
R2541 | T9925 | T9923 | pobj | tissue,on |
R2542 | T9926 | T9925 | prep | from,tissue |
R2543 | T9927 | T9928 | quantmod | 30,32 |
R2544 | T9928 | T9930 | nummod | 32,children |
R2545 | T9929 | T9928 | quantmod | of,32 |
R2546 | T9930 | T9926 | pobj | children,from |
R2547 | T9931 | T9930 | amod | deceased,children |
R2548 | T9932 | T9930 | prep | with,children |
R2549 | T9933 | T9934 | det | an,diagnosis |
R2550 | T9934 | T9932 | pobj | diagnosis,with |
R2551 | T9935 | T9934 | amod | anatomic,diagnosis |
R2552 | T9936 | T9934 | prep | of,diagnosis |
R2553 | T9937 | T9938 | amod | diaphragmatic,defect |
R2554 | T9938 | T9936 | pobj | defect,of |
R2555 | T9939 | T9925 | acl | evaluated,tissue |
R2556 | T9940 | T9939 | prep | at,evaluated |
R2557 | T9941 | T9942 | det | the,Hospital |
R2558 | T9942 | T9940 | pobj | Hospital,at |
R2559 | T9943 | T9942 | poss | Children,Hospital |
R2560 | T9944 | T9943 | case | 's,Children |
R2561 | T9945 | T9942 | prep | in,Hospital |
R2562 | T9946 | T9945 | pobj | Boston,in |
R2563 | T9947 | T9946 | punct | ", ",Boston |
R2564 | T9948 | T9946 | npadvmod | Massachusetts,Boston |
R2565 | T9949 | T9939 | punct | ", ",evaluated |
R2566 | T9950 | T9939 | prep | between,evaluated |
R2567 | T9951 | T9950 | pobj | 1993,between |
R2568 | T9952 | T9951 | cc | and,1993 |
R2569 | T9953 | T9951 | conj | 2003,1993 |
R2570 | T9954 | T9921 | punct | .,performed |
R2571 | T9956 | T9957 | compound | Autopsy,reports |
R2572 | T9957 | T9958 | nsubjpass | reports,reviewed |
R2573 | T9959 | T9958 | auxpass | were,reviewed |
R2574 | T9960 | T9961 | aux | to,determine |
R2575 | T9961 | T9958 | advcl | determine,reviewed |
R2576 | T9962 | T9963 | det | the,diagnoses |
R2577 | T9963 | T9961 | dobj | diagnoses,determine |
R2578 | T9964 | T9963 | amod | specific,diagnoses |
R2579 | T9965 | T9958 | punct | .,reviewed |
R2580 | T9967 | T9968 | prep | Of,had |
R2581 | T9969 | T9970 | det | these,cases |
R2582 | T9970 | T9967 | pobj | cases,Of |
R2583 | T9971 | T9970 | nummod | 30,cases |
R2584 | T9972 | T9968 | punct | ", ",had |
R2585 | T9973 | T9968 | nsubj | 17,had |
R2586 | T9974 | T9975 | punct | (,% |
R2587 | T9975 | T9973 | parataxis | %,17 |
R2588 | T9976 | T9975 | nummod | 57,% |
R2589 | T9977 | T9975 | punct | ),% |
R2590 | T9978 | T9979 | compound | Bochdalek,CDH |
R2591 | T9979 | T9968 | dobj | CDH,had |
R2592 | T9980 | T9968 | punct | ", ",had |
R2593 | T9981 | T9982 | nsubj | two,had |
R2594 | T9982 | T9968 | conj | had,had |
R2595 | T9983 | T9984 | punct | (,% |
R2596 | T9984 | T9981 | parataxis | %,two |
R2597 | T9985 | T9984 | nummod | 7,% |
R2598 | T9986 | T9984 | punct | ),% |
R2599 | T9987 | T9988 | amod | diaphragmatic,agenesis |
R2600 | T9988 | T9982 | dobj | agenesis,had |
R2601 | T9989 | T9982 | punct | ", ",had |
R2602 | T9990 | T9991 | nsubj | seven,had |
R2603 | T9991 | T9982 | conj | had,had |
R2604 | T9992 | T9993 | punct | (,% |
R2605 | T9993 | T9990 | parataxis | %,seven |
R2606 | T9994 | T9993 | nummod | 23,% |
R2607 | T9995 | T9993 | punct | ),% |
R2608 | T9996 | T9997 | amod | diaphragmatic,eventration |
R2609 | T9997 | T9991 | dobj | eventration,had |
R2610 | T9998 | T9997 | punct | /,eventration |
R2611 | T9999 | T10000 | compound | muscularization,defects |
R2612 | T10000 | T9997 | appos | defects,eventration |
R2613 | T10001 | T9997 | punct | (,eventration |
R2614 | T10002 | T9997 | prep | without,eventration |
R2615 | T10003 | T10004 | compound | Bochdalek,CDH |
R2616 | T10004 | T10002 | pobj | CDH,without |
R2617 | T10005 | T9991 | punct | ),had |
R2618 | T10006 | T9991 | punct | ", ",had |
R2619 | T10007 | T9991 | cc | and,had |
R2620 | T10008 | T10009 | nsubj | four,had |
R2621 | T10009 | T9991 | conj | had,had |
R2622 | T10010 | T10011 | punct | (,% |
R2623 | T10011 | T10008 | parataxis | %,four |
R2624 | T10012 | T10011 | nummod | 13,% |
R2625 | T10013 | T10011 | punct | ),% |
R2626 | T10014 | T10015 | compound | Bochdalek,hernia |
R2627 | T10015 | T10009 | dobj | hernia,had |
R2628 | T10016 | T10015 | prep | of,hernia |
R2629 | T10017 | T10018 | nummod | one,hemidiaphragm |
R2630 | T10018 | T10016 | pobj | hemidiaphragm,of |
R2631 | T10019 | T10015 | cc | and,hernia |
R2632 | T10020 | T10015 | conj | eventration,hernia |
R2633 | T10021 | T10020 | prep | of,eventration |
R2634 | T10022 | T10023 | det | the,other |
R2635 | T10023 | T10021 | pobj | other,of |
R2636 | T10024 | T10009 | punct | .,had |
R2637 | T10026 | T10027 | amod | Pulmonary,hypoplasia |
R2638 | T10027 | T10028 | nsubjpass | hypoplasia,assessed |
R2639 | T10029 | T10028 | auxpass | was,assessed |
R2640 | T10030 | T10028 | advcl | using,assessed |
R2641 | T10031 | T10032 | compound | lung,body |
R2642 | T10032 | T10034 | compound | body,ratio |
R2643 | T10033 | T10032 | punct | /,body |
R2644 | T10034 | T10030 | dobj | ratio,using |
R2645 | T10035 | T10034 | compound | weight,ratio |
R2646 | T10036 | T10034 | cc | and,ratio |
R2647 | T10037 | T10038 | amod | radial,counts |
R2648 | T10038 | T10034 | conj | counts,ratio |
R2649 | T10039 | T10038 | amod | alveolar,counts |
R2650 | T10040 | T10041 | punct | [,26 |
R2651 | T10041 | T10028 | parataxis | 26,assessed |
R2652 | T10042 | T10041 | punct | ],26 |
R2653 | T10043 | T10028 | punct | .,assessed |
R2654 | T10045 | T10046 | det | The,material |
R2655 | T10046 | T10047 | nsubj | material,included |
R2656 | T10048 | T10046 | amod | available,material |
R2657 | T10049 | T10048 | prep | for,available |
R2658 | T10050 | T10049 | pobj | review,for |
R2659 | T10051 | T10052 | amod | written,reports |
R2660 | T10052 | T10047 | dobj | reports,included |
R2661 | T10053 | T10052 | cc | and,reports |
R2662 | T10054 | T10055 | amod | histologic,slides |
R2663 | T10055 | T10052 | conj | slides,reports |
R2664 | T10056 | T10047 | prep | in,included |
R2665 | T10057 | T10058 | det | all,cases |
R2666 | T10058 | T10056 | pobj | cases,in |
R2667 | T10059 | T10047 | cc | and,included |
R2668 | T10060 | T10061 | amod | gross,kodachromes |
R2669 | T10061 | T10047 | conj | kodachromes,included |
R2670 | T10062 | T10061 | prep | in,kodachromes |
R2671 | T10063 | T10064 | det | a,subset |
R2672 | T10064 | T10062 | pobj | subset,in |
R2673 | T10065 | T10064 | prep | of,subset |
R2674 | T10066 | T10065 | pobj | cases,of |
R2675 | T10067 | T10047 | punct | .,included |
R2676 | T10069 | T10070 | nummod | One,child |
R2677 | T10070 | T10071 | nsubj | child,carried |
R2678 | T10072 | T10073 | det | a,change |
R2679 | T10073 | T10071 | dobj | change,carried |
R2680 | T10074 | T10075 | advmod | highly,significant |
R2681 | T10075 | T10073 | amod | significant,change |
R2682 | T10076 | T10073 | compound | FOG2,change |
R2683 | T10077 | T10073 | compound | sequence,change |
R2684 | T10078 | T10071 | punct | .,carried |
R2685 | T10080 | T10081 | det | The,patient |
R2686 | T10081 | T10082 | nsubj | patient,was |
R2687 | T10083 | T10084 | det | a,girl |
R2688 | T10084 | T10082 | attr | girl,was |
R2689 | T10085 | T10086 | amod | full,term |
R2690 | T10086 | T10084 | nmod | term,girl |
R2691 | T10087 | T10086 | punct | -,term |
R2692 | T10088 | T10089 | nummod | "3,500",g |
R2693 | T10089 | T10084 | compound | g,girl |
R2694 | T10090 | T10089 | punct | -,g |
R2695 | T10091 | T10084 | compound | baby,girl |
R2696 | T10092 | T10093 | dep | who,developed |
R2697 | T10093 | T10084 | relcl | developed,girl |
R2698 | T10094 | T10095 | amod | severe,failure |
R2699 | T10095 | T10093 | dobj | failure,developed |
R2700 | T10096 | T10095 | amod | respiratory,failure |
R2701 | T10097 | T10093 | prep | at,developed |
R2702 | T10098 | T10097 | pobj | birth,at |
R2703 | T10099 | T10093 | cc | and,developed |
R2704 | T10100 | T10093 | conj | died,developed |
R2705 | T10101 | T10100 | prep | after,died |
R2706 | T10102 | T10103 | nummod | 5,h |
R2707 | T10103 | T10101 | pobj | h,after |
R2708 | T10104 | T10103 | prep | of,h |
R2709 | T10105 | T10104 | pobj | resuscitation,of |
R2710 | T10106 | T10082 | punct | .,was |
R2711 | T10108 | T10109 | compound | Antemortem,radiographs |
R2712 | T10109 | T10110 | nsubj | radiographs,showed |
R2713 | T10111 | T10112 | amod | opacified,fields |
R2714 | T10112 | T10110 | dobj | fields,showed |
R2715 | T10113 | T10112 | compound | lung,fields |
R2716 | T10114 | T10112 | cc | and,fields |
R2717 | T10115 | T10116 | amod | possible,bowel |
R2718 | T10116 | T10112 | conj | bowel,fields |
R2719 | T10117 | T10116 | prep | in,bowel |
R2720 | T10118 | T10119 | det | the,chest |
R2721 | T10119 | T10117 | pobj | chest,in |
R2722 | T10120 | T10110 | punct | .,showed |
R2723 | T10122 | T10123 | det | The,patient |
R2724 | T10123 | T10124 | poss | patient,diagnosis |
R2725 | T10124 | T10127 | nsubj | diagnosis,was |
R2726 | T10125 | T10123 | case | 's,patient |
R2727 | T10126 | T10124 | amod | clinical,diagnosis |
R2728 | T10128 | T10127 | attr | CDH,was |
R2729 | T10129 | T10127 | punct | .,was |
R2730 | T10131 | T10132 | nsubj | Review,revealed |
R2731 | T10133 | T10131 | prep | of,Review |
R2732 | T10134 | T10135 | compound | autopsy,material |
R2733 | T10135 | T10133 | pobj | material,of |
R2734 | T10136 | T10137 | amod | severe,hypoplasia |
R2735 | T10137 | T10132 | dobj | hypoplasia,revealed |
R2736 | T10138 | T10137 | amod | bilateral,hypoplasia |
R2737 | T10139 | T10137 | amod | pulmonary,hypoplasia |
R2738 | T10140 | T10141 | punct | (,27 |
R2739 | T10141 | T10137 | parataxis | 27,hypoplasia |
R2740 | T10142 | T10143 | amod | combined,weight |
R2741 | T10143 | T10145 | dep | weight,g |
R2742 | T10144 | T10143 | compound | lung,weight |
R2743 | T10145 | T10141 | dep | g,27 |
R2744 | T10146 | T10145 | punct | ", ",g |
R2745 | T10147 | T10145 | nummod | 11.1,g |
R2746 | T10148 | T10141 | punct | ;,27 |
R2747 | T10149 | T10141 | dep | expected,27 |
R2748 | T10150 | T10149 | prep | for,expected |
R2749 | T10151 | T10152 | compound | body,weight |
R2750 | T10152 | T10150 | pobj | weight,for |
R2751 | T10153 | T10152 | compound | length,weight |
R2752 | T10154 | T10152 | punct | /,weight |
R2753 | T10155 | T10149 | punct | ", ",expected |
R2754 | T10156 | T10157 | quantmod | 46.8,26.2 |
R2755 | T10157 | T10159 | nummod | 26.2,g |
R2756 | T10158 | T10157 | punct | ±,26.2 |
R2757 | T10159 | T10149 | dep | g,expected |
R2758 | T10160 | T10141 | punct | ;,27 |
R2759 | T10161 | T10141 | punct | [,27 |
R2760 | T10162 | T10141 | punct | ],27 |
R2761 | T10163 | T10141 | punct | ),27 |
R2762 | T10164 | T10137 | punct | ", ",hypoplasia |
R2763 | T10165 | T10166 | advmod | most,markedly |
R2764 | T10166 | T10167 | advmod | markedly,involving |
R2765 | T10167 | T10137 | acl | involving,hypoplasia |
R2766 | T10168 | T10169 | det | the,lung |
R2767 | T10169 | T10167 | dobj | lung,involving |
R2768 | T10170 | T10169 | amod | left,lung |
R2769 | T10171 | T10132 | punct | .,revealed |
R2770 | T10173 | T10174 | det | The,ratio |
R2771 | T10174 | T10179 | nsubj | ratio,was |
R2772 | T10175 | T10174 | nmod | lung,ratio |
R2773 | T10176 | T10177 | punct | /,body |
R2774 | T10177 | T10175 | prep | body,lung |
R2775 | T10178 | T10174 | compound | weight,ratio |
R2776 | T10180 | T10179 | attr | 0.0037,was |
R2777 | T10181 | T10182 | punct | (,0.010 |
R2778 | T10182 | T10179 | parataxis | 0.010,was |
R2779 | T10183 | T10182 | nsubj | expected,0.010 |
R2780 | T10184 | T10182 | punct | >,0.010 |
R2781 | T10185 | T10182 | punct | ),0.010 |
R2782 | T10186 | T10187 | punct | [,28 |
R2783 | T10187 | T10179 | parataxis | 28,was |
R2784 | T10188 | T10187 | punct | ],28 |
R2785 | T10189 | T10179 | punct | .,was |
R2786 | T10191 | T10192 | expl | There,were |
R2787 | T10193 | T10194 | det | a,number |
R2788 | T10194 | T10192 | attr | number,were |
R2789 | T10195 | T10194 | amod | reduced,number |
R2790 | T10196 | T10194 | prep | of,number |
R2791 | T10197 | T10198 | amod | bronchial,generations |
R2792 | T10198 | T10196 | pobj | generations,of |
R2793 | T10199 | T10192 | punct | ", ",were |
R2794 | T10200 | T10192 | cc | and,were |
R2795 | T10201 | T10202 | det | the,count |
R2796 | T10202 | T10205 | nsubj | count,was |
R2797 | T10203 | T10202 | amod | radial,count |
R2798 | T10204 | T10202 | amod | alveolar,count |
R2799 | T10205 | T10192 | conj | was,were |
R2800 | T10206 | T10207 | quantmod | 2,3 |
R2801 | T10207 | T10205 | attr | 3,was |
R2802 | T10208 | T10207 | punct | –,3 |
R2803 | T10209 | T10210 | punct | (,5 |
R2804 | T10210 | T10205 | parataxis | 5,was |
R2805 | T10211 | T10210 | nsubj | expected,5 |
R2806 | T10212 | T10210 | punct | =,5 |
R2807 | T10213 | T10210 | punct | ),5 |
R2808 | T10214 | T10215 | punct | [,29 |
R2809 | T10215 | T10205 | parataxis | 29,was |
R2810 | T10216 | T10215 | punct | ],29 |
R2811 | T10217 | T10205 | punct | .,was |
R2812 | T10219 | T10220 | expl | There,were |
R2813 | T10221 | T10222 | amod | incomplete,fissures |
R2814 | T10222 | T10220 | attr | fissures,were |
R2815 | T10223 | T10222 | compound | lung,fissures |
R2816 | T10224 | T10220 | advmod | bilaterally,were |
R2817 | T10225 | T10220 | punct | .,were |
R2818 | T10227 | T10228 | det | A,eventration |
R2819 | T10228 | T10232 | nsubj | eventration,was |
R2820 | T10229 | T10228 | amod | deep,eventration |
R2821 | T10230 | T10228 | amod | posterior,eventration |
R2822 | T10231 | T10228 | amod | diaphragmatic,eventration |
R2823 | T10233 | T10232 | acomp | present,was |
R2824 | T10234 | T10232 | prep | on,was |
R2825 | T10235 | T10236 | det | the,side |
R2826 | T10236 | T10234 | pobj | side,on |
R2827 | T10237 | T10236 | amod | left,side |
R2828 | T10238 | T10232 | punct | .,was |
R2829 | T10240 | T10241 | advmod | Additionally,encircled |
R2830 | T10242 | T10241 | punct | ", ",encircled |
R2831 | T10243 | T10244 | nummod | two,bands |
R2832 | T10244 | T10241 | nsubj | bands,encircled |
R2833 | T10245 | T10244 | amod | muscularized,bands |
R2834 | T10246 | T10244 | amod | ligamentous,bands |
R2835 | T10247 | T10244 | acl | resembling,bands |
R2836 | T10248 | T10249 | amod | diaphragmatic,remnants |
R2837 | T10249 | T10247 | dobj | remnants,resembling |
R2838 | T10250 | T10251 | det | the,lobe |
R2839 | T10251 | T10241 | dobj | lobe,encircled |
R2840 | T10252 | T10251 | amod | left,lobe |
R2841 | T10253 | T10251 | prep | of,lobe |
R2842 | T10254 | T10255 | det | the,liver |
R2843 | T10255 | T10253 | pobj | liver,of |
R2844 | T10256 | T10241 | punct | ", ",encircled |
R2845 | T10257 | T10241 | advcl | creating,encircled |
R2846 | T10258 | T10259 | det | an,contour |
R2847 | T10259 | T10257 | dobj | contour,creating |
R2848 | T10260 | T10259 | amod | abnormal,contour |
R2849 | T10261 | T10259 | amod | fissured,contour |
R2850 | T10262 | T10259 | compound | liver,contour |
R2851 | T10263 | T10241 | punct | .,encircled |
R2852 | T10265 | T10266 | advmod | Away,appeared |
R2853 | T10267 | T10265 | prep | from,Away |
R2854 | T10268 | T10269 | det | the,eventration |
R2855 | T10269 | T10267 | pobj | eventration,from |
R2856 | T10270 | T10266 | punct | ", ",appeared |
R2857 | T10271 | T10272 | det | the,diaphragm |
R2858 | T10272 | T10266 | nsubj | diaphragm,appeared |
R2859 | T10273 | T10274 | advmod | well,muscularized |
R2860 | T10274 | T10266 | oprd | muscularized,appeared |
R2861 | T10275 | T10266 | punct | ", ",appeared |
R2862 | T10276 | T10266 | advcl | measuring,appeared |
R2863 | T10277 | T10278 | nummod | 0.3,cm |
R2864 | T10278 | T10276 | dobj | cm,measuring |
R2865 | T10279 | T10278 | prep | in,cm |
R2866 | T10280 | T10279 | pobj | thickness,in |
R2867 | T10281 | T10266 | punct | .,appeared |
R2868 | T10283 | T10284 | det | A,autopsy |
R2869 | T10284 | T10286 | nsubj | autopsy,revealed |
R2870 | T10285 | T10284 | amod | complete,autopsy |
R2871 | T10286 | T10287 | ccomp | revealed,determined |
R2872 | T10288 | T10289 | det | no,malformations |
R2873 | T10289 | T10286 | dobj | malformations,revealed |
R2874 | T10290 | T10289 | amod | other,malformations |
R2875 | T10291 | T10287 | punct | ;,determined |
R2876 | T10292 | T10293 | det | the,heart |
R2877 | T10293 | T10287 | nsubjpass | heart,determined |
R2878 | T10294 | T10287 | auxpass | was,determined |
R2879 | T10295 | T10296 | aux | to,be |
R2880 | T10296 | T10287 | xcomp | be,determined |
R2881 | T10297 | T10298 | advmod | grossly,normal |
R2882 | T10298 | T10296 | acomp | normal,be |
R2883 | T10299 | T10287 | cc | and,determined |
R2884 | T10300 | T10301 | auxpass | was,donated |
R2885 | T10301 | T10287 | conj | donated,determined |
R2886 | T10302 | T10301 | prep | for,donated |
R2887 | T10303 | T10304 | compound | valve,harvest |
R2888 | T10304 | T10302 | pobj | harvest,for |
R2889 | T10305 | T10287 | punct | .,determined |
R2890 | T10307 | T10308 | compound | Sequence,analysis |
R2891 | T10308 | T10309 | nsubj | analysis,revealed |
R2892 | T10310 | T10311 | det | a,change |
R2893 | T10311 | T10309 | dobj | change,revealed |
R2894 | T10312 | T10311 | nmod | cytosine,change |
R2895 | T10313 | T10312 | prep | to,cytosine |
R2896 | T10314 | T10313 | pobj | thymine,to |
R2897 | T10315 | T10311 | amod | heterozygous,change |
R2898 | T10316 | T10311 | prep | in,change |
R2899 | T10317 | T10316 | pobj | exon,in |
R2900 | T10318 | T10317 | nummod | 4,exon |
R2901 | T10319 | T10320 | dep | that,changes |
R2902 | T10320 | T10311 | relcl | changes,change |
R2903 | T10321 | T10322 | det | the,acid |
R2904 | T10322 | T10320 | dobj | acid,changes |
R2905 | T10323 | T10322 | amod | 112th,acid |
R2906 | T10324 | T10322 | compound | amino,acid |
R2907 | T10325 | T10320 | prep | from,changes |
R2908 | T10326 | T10325 | pobj | arginine,from |
R2909 | T10327 | T10320 | prep | to,changes |
R2910 | T10328 | T10329 | det | a,codon |
R2911 | T10329 | T10327 | pobj | codon,to |
R2912 | T10330 | T10329 | compound | stop,codon |
R2913 | T10331 | T10309 | punct | .,revealed |
R2914 | T10333 | T10334 | det | This,mutation |
R2915 | T10334 | T10335 | nsubj | mutation,produces |
R2916 | T10336 | T10337 | det | a,peptide |
R2917 | T10337 | T10335 | dobj | peptide,produces |
R2918 | T10338 | T10339 | advmod | severely,truncated |
R2919 | T10339 | T10337 | amod | truncated,peptide |
R2920 | T10340 | T10341 | dep | that,contain |
R2921 | T10341 | T10337 | relcl | contain,peptide |
R2922 | T10342 | T10341 | aux | does,contain |
R2923 | T10343 | T10341 | neg | not,contain |
R2924 | T10344 | T10345 | compound | zinc,finger |
R2925 | T10345 | T10346 | compound | finger,domains |
R2926 | T10346 | T10341 | dobj | domains,contain |
R2927 | T10347 | T10348 | punct | (,Figure |
R2928 | T10348 | T10335 | parataxis | Figure,produces |
R2929 | T10349 | T10348 | nummod | 7,Figure |
R2930 | T10350 | T10348 | punct | ),Figure |
R2931 | T10351 | T10335 | punct | .,produces |
R2932 | T10353 | T10354 | det | This,change |
R2933 | T10354 | T10356 | nsubj | change,was |
R2934 | T10355 | T10354 | compound | base,change |
R2935 | T10357 | T10356 | neg | not,was |
R2936 | T10358 | T10356 | acomp | present,was |
R2937 | T10359 | T10356 | prep | in,was |
R2938 | T10360 | T10361 | det | the,analysis |
R2939 | T10361 | T10359 | pobj | analysis,in |
R2940 | T10362 | T10361 | prep | of,analysis |
R2941 | T10363 | T10362 | pobj | DNA,of |
R2942 | T10364 | T10363 | prep | from,DNA |
R2943 | T10365 | T10366 | nummod | 400,adults |
R2944 | T10366 | T10364 | pobj | adults,from |
R2945 | T10367 | T10366 | amod | normal,adults |
R2946 | T10368 | T10356 | punct | .,was |
R2947 | T10370 | T10371 | aux | To,assess |
R2948 | T10371 | T10372 | advcl | assess,examined |
R2949 | T10373 | T10374 | det | the,likelihood |
R2950 | T10374 | T10371 | dobj | likelihood,assess |
R2951 | T10375 | T10376 | mark | that,was |
R2952 | T10376 | T10374 | acl | was,likelihood |
R2953 | T10377 | T10378 | det | the,mutation |
R2954 | T10378 | T10376 | nsubj | mutation,was |
R2955 | T10379 | T10376 | acomp | causal,was |
R2956 | T10380 | T10379 | prep | for,causal |
R2957 | T10381 | T10382 | det | the,phenotype |
R2958 | T10382 | T10380 | pobj | phenotype,for |
R2959 | T10383 | T10382 | amod | developmental,phenotype |
R2960 | T10384 | T10372 | punct | ", ",examined |
R2961 | T10385 | T10372 | nsubj | we,examined |
R2962 | T10386 | T10387 | det | both,parents |
R2963 | T10387 | T10372 | dobj | parents,examined |
R2964 | T10388 | T10372 | punct | .,examined |
R2965 | T10390 | T10391 | nsubjpass | Paternity,confirmed |
R2966 | T10392 | T10391 | auxpass | was,confirmed |
R2967 | T10393 | T10391 | punct | ", ",confirmed |
R2968 | T10394 | T10391 | cc | and,confirmed |
R2969 | T10395 | T10396 | compound | sequence,analysis |
R2970 | T10396 | T10397 | nsubj | analysis,revealed |
R2971 | T10397 | T10391 | conj | revealed,confirmed |
R2972 | T10398 | T10399 | mark | that,carried |
R2973 | T10399 | T10397 | ccomp | carried,revealed |
R2974 | T10400 | T10401 | det | the,parent |
R2975 | T10401 | T10399 | nsubj | parent,carried |
R2976 | T10402 | T10401 | preconj | neither,parent |
R2977 | T10403 | T10404 | det | this,mutation |
R2978 | T10404 | T10399 | dobj | mutation,carried |
R2979 | T10405 | T10397 | punct | ", ",revealed |
R2980 | T10406 | T10397 | advcl | proving,revealed |
R2981 | T10407 | T10408 | mark | that,had |
R2982 | T10408 | T10406 | ccomp | had,proving |
R2983 | T10409 | T10410 | det | the,patient |
R2984 | T10410 | T10408 | nsubj | patient,had |
R2985 | T10411 | T10412 | det | a,mutation |
R2986 | T10412 | T10408 | dobj | mutation,had |
R2987 | T10413 | T10414 | advmod | de,novo |
R2988 | T10414 | T10412 | amod | novo,mutation |
R2989 | T10415 | T10408 | prep | in,had |
R2990 | T10416 | T10415 | pobj | FOG2,in |
R2991 | T10417 | T10418 | punct | (,Figure |
R2992 | T10418 | T10397 | parataxis | Figure,revealed |
R2993 | T10419 | T10418 | nummod | 7,Figure |
R2994 | T10420 | T10418 | punct | ),Figure |
R2995 | T10421 | T10397 | punct | .,revealed |
R3008 | T13037 | T13038 | amod | Congenital,defects |
R3009 | T13038 | T13040 | nsubj | defects,are |
R3010 | T13039 | T13038 | amod | diaphragmatic,defects |
R3011 | T13041 | T13042 | det | a,group |
R3012 | T13042 | T13040 | attr | group,are |
R3013 | T13043 | T13042 | amod | heterogeneous,group |
R3014 | T13044 | T13042 | prep | of,group |
R3015 | T13045 | T13044 | pobj | disorders,of |
R3016 | T13046 | T13045 | prep | of,disorders |
R3017 | T13047 | T13048 | amod | unknown,etiology |
R3018 | T13048 | T13046 | pobj | etiology,of |
R3019 | T13049 | T13040 | punct | .,are |
R3020 | T13051 | T13052 | det | The,defects |
R3021 | T13052 | T13053 | nsubj | defects,include |
R3022 | T13054 | T13055 | dep | that,present |
R3023 | T13055 | T13052 | relcl | present,defects |
R3024 | T13056 | T13055 | prep | in,present |
R3025 | T13057 | T13058 | det | the,period |
R3026 | T13058 | T13056 | pobj | period,in |
R3027 | T13059 | T13060 | advmod | pre,perinatal |
R3028 | T13060 | T13058 | amod | perinatal,period |
R3029 | T13061 | T13060 | punct | -,perinatal |
R3030 | T13062 | T13060 | cc | or,perinatal |
R3031 | T13063 | T13064 | compound | Bochdalek,hernia |
R3032 | T13064 | T13053 | dobj | hernia,include |
R3033 | T13065 | T13064 | punct | ", ",hernia |
R3034 | T13066 | T13067 | amod | diaphragmatic,aplasia |
R3035 | T13067 | T13064 | conj | aplasia,hernia |
R3036 | T13068 | T13067 | punct | ", ",aplasia |
R3037 | T13069 | T13067 | cc | and,aplasia |
R3038 | T13070 | T13071 | amod | various,degrees |
R3039 | T13071 | T13067 | conj | degrees,aplasia |
R3040 | T13072 | T13071 | prep | of,degrees |
R3041 | T13073 | T13074 | compound | muscularization,defects |
R3042 | T13074 | T13072 | pobj | defects,of |
R3043 | T13075 | T13074 | cc | or,defects |
R3044 | T13076 | T13074 | conj | eventrations,defects |
R3045 | T13077 | T13053 | punct | .,include |
R3046 | T13079 | T13080 | amod | Different,types |
R3047 | T13080 | T13081 | nsubj | types,occur |
R3048 | T13082 | T13080 | prep | of,types |
R3049 | T13083 | T13082 | pobj | defects,of |
R3050 | T13084 | T13081 | prep | in,occur |
R3051 | T13085 | T13086 | det | the,patients |
R3052 | T13086 | T13084 | pobj | patients,in |
R3053 | T13087 | T13086 | amod | same,patients |
R3054 | T13088 | T13084 | cc | or,in |
R3055 | T13089 | T13084 | conj | in,in |
R3056 | T13090 | T13089 | pobj | siblings,in |
R3057 | T13091 | T13081 | punct | ", ",occur |
R3058 | T13092 | T13081 | advcl | suggesting,occur |
R3059 | T13093 | T13094 | nsubj | these,represent |
R3060 | T13094 | T13092 | advcl | represent,suggesting |
R3061 | T13095 | T13096 | amod | variable,expression |
R3062 | T13096 | T13094 | dobj | expression,represent |
R3063 | T13097 | T13096 | prep | of,expression |
R3064 | T13098 | T13099 | det | the,pathogenesis |
R3065 | T13099 | T13097 | pobj | pathogenesis,of |
R3066 | T13100 | T13099 | amod | same,pathogenesis |
R3067 | T13101 | T13099 | amod | underlying,pathogenesis |
R3068 | T13102 | T13103 | punct | [,31 |
R3069 | T13103 | T13081 | parataxis | 31,occur |
R3070 | T13104 | T13103 | nummod | 30,31 |
R3071 | T13105 | T13103 | punct | ",",31 |
R3072 | T13106 | T13103 | punct | ],31 |
R3073 | T13107 | T13081 | punct | .,occur |
R3074 | T13109 | T13110 | amod | Clinical,differentiation |
R3075 | T13110 | T13111 | nsubj | differentiation,be |
R3076 | T13112 | T13110 | prep | between,differentiation |
R3077 | T13113 | T13114 | det | these,defects |
R3078 | T13114 | T13112 | pobj | defects,between |
R3079 | T13115 | T13111 | aux | may,be |
R3080 | T13116 | T13117 | advmod | very,difficult |
R3081 | T13117 | T13111 | acomp | difficult,be |
R3082 | T13118 | T13111 | punct | ", ",be |
R3083 | T13119 | T13120 | mark | as,is |
R3084 | T13120 | T13111 | advcl | is,be |
R3085 | T13121 | T13122 | det | the,diaphragm |
R3086 | T13122 | T13120 | nsubj | diaphragm,is |
R3087 | T13123 | T13122 | amod | residual,diaphragm |
R3088 | T13124 | T13122 | amod | membranous,diaphragm |
R3089 | T13125 | T13122 | prep | of,diaphragm |
R3090 | T13126 | T13127 | det | a,defect |
R3091 | T13127 | T13125 | pobj | defect,of |
R3092 | T13128 | T13127 | compound | muscularization,defect |
R3093 | T13129 | T13120 | acomp | thin,is |
R3094 | T13130 | T13120 | cc | and,is |
R3095 | T13131 | T13132 | aux | may,be |
R3096 | T13132 | T13120 | conj | be,is |
R3097 | T13133 | T13132 | neg | not,be |
R3098 | T13134 | T13135 | advmod | easily,visible |
R3099 | T13135 | T13132 | acomp | visible,be |
R3100 | T13136 | T13132 | prep | on,be |
R3101 | T13137 | T13138 | amod | prenatal,ultrasound |
R3102 | T13138 | T13136 | pobj | ultrasound,on |
R3103 | T13139 | T13138 | cc | or,ultrasound |
R3104 | T13140 | T13141 | amod | postnatal,radiographs |
R3105 | T13141 | T13138 | conj | radiographs,ultrasound |
R3106 | T13142 | T13141 | compound | chest,radiographs |
R3107 | T13143 | T13144 | punct | [,32 |
R3108 | T13144 | T13111 | parataxis | 32,be |
R3109 | T13145 | T13144 | punct | ],32 |
R3110 | T13146 | T13111 | punct | .,be |
R3111 | T13148 | T13149 | mark | Although,considered |
R3112 | T13149 | T13155 | advcl | considered,been |
R3113 | T13150 | T13151 | amod | diaphragmatic,defects |
R3114 | T13151 | T13149 | nsubjpass | defects,considered |
R3115 | T13152 | T13151 | compound | muscularization,defects |
R3116 | T13153 | T13149 | auxpass | were,considered |
R3117 | T13154 | T13149 | advmod | historically,considered |
R3118 | T13156 | T13157 | aux | to,be |
R3119 | T13157 | T13149 | xcomp | be,considered |
R3120 | T13158 | T13157 | acomp | predictive,be |
R3121 | T13159 | T13158 | prep | of,predictive |
R3122 | T13160 | T13161 | det | a,outcome |
R3123 | T13161 | T13159 | pobj | outcome,of |
R3124 | T13162 | T13161 | amod | good,outcome |
R3125 | T13163 | T13155 | punct | ", ",been |
R3126 | T13164 | T13155 | expl | there,been |
R3127 | T13165 | T13155 | aux | have,been |
R3128 | T13166 | T13167 | amod | inadequate,studies |
R3129 | T13167 | T13155 | attr | studies,been |
R3130 | T13168 | T13169 | npadvmod | population,based |
R3131 | T13169 | T13167 | amod | based,studies |
R3132 | T13170 | T13169 | punct | -,based |
R3133 | T13171 | T13172 | dep | that,include |
R3134 | T13172 | T13167 | relcl | include,studies |
R3135 | T13173 | T13174 | amod | fetal,cases |
R3136 | T13174 | T13172 | dobj | cases,include |
R3137 | T13175 | T13173 | cc | or,fetal |
R3138 | T13176 | T13173 | conj | neonatal,fetal |
R3139 | T13177 | T13174 | cc | and,cases |
R3140 | T13178 | T13179 | compound | autopsy,diagnoses |
R3141 | T13179 | T13174 | conj | diagnoses,cases |
R3142 | T13180 | T13181 | aux | to,make |
R3143 | T13181 | T13172 | advcl | make,include |
R3144 | T13182 | T13183 | det | this,conclusion |
R3145 | T13183 | T13184 | nsubj | conclusion,definitive |
R3146 | T13184 | T13181 | ccomp | definitive,make |
R3147 | T13185 | T13155 | punct | .,been |
R3148 | T13187 | T13188 | prep | In,indicate |
R3149 | T13189 | T13187 | pobj | fact,In |
R3150 | T13190 | T13188 | punct | ", ",indicate |
R3151 | T13191 | T13192 | det | the,series |
R3152 | T13192 | T13188 | nsubj | series,indicate |
R3153 | T13193 | T13192 | prep | of,series |
R3154 | T13194 | T13193 | pobj | patients,of |
R3155 | T13195 | T13196 | nsubj | we,report |
R3156 | T13196 | T13194 | advcl | report,patients |
R3157 | T13197 | T13196 | advmod | here,report |
R3158 | T13198 | T13192 | cc | and,series |
R3159 | T13199 | T13200 | det | the,literature |
R3160 | T13200 | T13192 | conj | literature,series |
R3161 | T13201 | T13200 | amod | published,literature |
R3162 | T13202 | T13203 | mark | that,associated |
R3163 | T13203 | T13188 | ccomp | associated,indicate |
R3164 | T13204 | T13205 | det | an,defect |
R3165 | T13205 | T13203 | nsubjpass | defect,associated |
R3166 | T13206 | T13205 | compound | eventration,defect |
R3167 | T13207 | T13203 | aux | may,associated |
R3168 | T13208 | T13203 | auxpass | be,associated |
R3169 | T13209 | T13203 | prep | with,associated |
R3170 | T13210 | T13209 | pobj | displacement,with |
R3171 | T13211 | T13210 | prep | of,displacement |
R3172 | T13212 | T13213 | amod | abdominal,contents |
R3173 | T13213 | T13211 | pobj | contents,of |
R3174 | T13214 | T13209 | cc | and,with |
R3175 | T13215 | T13214 | advmod | also,and |
R3176 | T13216 | T13209 | conj | with,with |
R3177 | T13217 | T13218 | amod | severe,hypoplasia |
R3178 | T13218 | T13216 | pobj | hypoplasia,with |
R3179 | T13219 | T13218 | amod | pulmonary,hypoplasia |
R3180 | T13220 | T13218 | cc | and,hypoplasia |
R3181 | T13221 | T13222 | amod | respiratory,insufficiency |
R3182 | T13222 | T13218 | conj | insufficiency,hypoplasia |
R3183 | T13223 | T13224 | punct | [,34 |
R3184 | T13224 | T13188 | parataxis | 34,indicate |
R3185 | T13225 | T13224 | nummod | 33,34 |
R3186 | T13226 | T13224 | punct | ",",34 |
R3187 | T13227 | T13224 | punct | ],34 |
R3188 | T13228 | T13188 | punct | .,indicate |
R3189 | T13230 | T13231 | amod | Numerous,abnormalities |
R3190 | T13231 | T13233 | nsubjpass | abnormalities,found |
R3191 | T13232 | T13231 | compound | chromosome,abnormalities |
R3192 | T13234 | T13233 | aux | have,found |
R3193 | T13235 | T13233 | auxpass | been,found |
R3194 | T13236 | T13233 | prep | in,found |
R3195 | T13237 | T13236 | pobj | association,in |
R3196 | T13238 | T13237 | prep | with,association |
R3197 | T13239 | T13240 | amod | congenital,abnormalities |
R3198 | T13240 | T13238 | pobj | abnormalities,with |
R3199 | T13241 | T13240 | compound | diaphragm,abnormalities |
R3200 | T13242 | T13243 | punct | [,35 |
R3201 | T13243 | T13233 | parataxis | 35,found |
R3202 | T13244 | T13243 | nummod | 12,35 |
R3203 | T13245 | T13243 | punct | ",",35 |
R3204 | T13246 | T13243 | punct | ],35 |
R3205 | T13247 | T13233 | punct | .,found |
R3206 | T13249 | T13250 | amod | Human,FOG2 |
R3207 | T13250 | T13251 | nsubj | FOG2,maps |
R3208 | T13252 | T13251 | prep | to,maps |
R3209 | T13253 | T13252 | pobj | Chromosome,to |
R3210 | T13254 | T13253 | nummod | 8q23.1,Chromosome |
R3211 | T13255 | T13251 | punct | ", ",maps |
R3212 | T13256 | T13251 | cc | and,maps |
R3213 | T13257 | T13251 | punct | ", ",maps |
R3214 | T13258 | T13259 | advmod | importantly,reported |
R3215 | T13259 | T13251 | conj | reported,maps |
R3216 | T13260 | T13259 | punct | ", ",reported |
R3217 | T13261 | T13262 | amod | several,patients |
R3218 | T13262 | T13259 | nsubjpass | patients,reported |
R3219 | T13263 | T13262 | prep | with,patients |
R3220 | T13264 | T13265 | compound | diaphragm,defects |
R3221 | T13265 | T13263 | pobj | defects,with |
R3222 | T13266 | T13265 | cc | and,defects |
R3223 | T13267 | T13265 | conj | rearrangements,defects |
R3224 | T13268 | T13267 | acl | involving,rearrangements |
R3225 | T13269 | T13270 | det | this,locus |
R3226 | T13270 | T13268 | dobj | locus,involving |
R3227 | T13271 | T13259 | aux | have,reported |
R3228 | T13272 | T13259 | auxpass | been,reported |
R3229 | T13273 | T13259 | punct | .,reported |
R3230 | T13275 | T13276 | advmod | Specifically,are |
R3231 | T13277 | T13276 | punct | ", ",are |
R3232 | T13278 | T13276 | expl | there,are |
R3233 | T13279 | T13280 | nummod | three,patients |
R3234 | T13280 | T13276 | attr | patients,are |
R3235 | T13281 | T13280 | amod | unrelated,patients |
R3236 | T13282 | T13280 | compound | CDH,patients |
R3237 | T13283 | T13280 | prep | with,patients |
R3238 | T13284 | T13285 | advmod | cytogenetically,balanced |
R3239 | T13285 | T13286 | amod | balanced,translocations |
R3240 | T13286 | T13283 | pobj | translocations,with |
R3241 | T13287 | T13286 | prep | at,translocations |
R3242 | T13288 | T13287 | cc | or,at |
R3243 | T13289 | T13287 | conj | near,at |
R3244 | T13290 | T13291 | det | the,locus |
R3245 | T13291 | T13289 | pobj | locus,near |
R3246 | T13292 | T13291 | compound | FOG2,locus |
R3247 | T13293 | T13294 | punct | [,37 |
R3248 | T13294 | T13276 | parataxis | 37,are |
R3249 | T13295 | T13294 | nummod | 36,37 |
R3250 | T13296 | T13294 | punct | ",",37 |
R3251 | T13297 | T13294 | punct | ],37 |
R3252 | T13298 | T13276 | punct | .,are |
R3253 | T13300 | T13301 | advmod | Additionally,died |
R3254 | T13302 | T13301 | punct | ", ",died |
R3255 | T13303 | T13304 | nummod | two,patients |
R3256 | T13304 | T13301 | nsubj | patients,died |
R3257 | T13305 | T13304 | prep | with,patients |
R3258 | T13306 | T13305 | pobj | deletions,with |
R3259 | T13307 | T13308 | advmod | apparently,encompassing |
R3260 | T13308 | T13306 | acl | encompassing,deletions |
R3261 | T13309 | T13310 | det | the,locus |
R3262 | T13310 | T13308 | dobj | locus,encompassing |
R3263 | T13311 | T13310 | compound | FOG2,locus |
R3264 | T13312 | T13301 | aux | have,died |
R3265 | T13313 | T13301 | prep | from,died |
R3266 | T13314 | T13315 | amod | multiple,anomalies |
R3267 | T13315 | T13313 | pobj | anomalies,from |
R3268 | T13316 | T13315 | amod | congenital,anomalies |
R3269 | T13317 | T13315 | prep | including,anomalies |
R3270 | T13318 | T13317 | pobj | CDH,including |
R3271 | T13319 | T13320 | punct | [,38 |
R3272 | T13320 | T13301 | parataxis | 38,died |
R3273 | T13321 | T13322 | punct | –,40 |
R3274 | T13322 | T13320 | prep | 40,38 |
R3275 | T13323 | T13320 | punct | ],38 |
R3276 | T13324 | T13301 | punct | .,died |
R3277 | T13326 | T13327 | nsubj | Inactivation,result |
R3278 | T13328 | T13326 | prep | of,Inactivation |
R3279 | T13329 | T13330 | det | this,gene |
R3280 | T13330 | T13328 | pobj | gene,of |
R3281 | T13331 | T13326 | prep | due,Inactivation |
R3282 | T13332 | T13331 | pcomp | to,due |
R3283 | T13333 | T13334 | amod | chromosomal,rearrangement |
R3284 | T13334 | T13331 | pobj | rearrangement,due |
R3285 | T13335 | T13334 | cc | or,rearrangement |
R3286 | T13336 | T13334 | conj | deletion,rearrangement |
R3287 | T13337 | T13327 | aux | would,result |
R3288 | T13338 | T13327 | prep | in,result |
R3289 | T13339 | T13340 | det | a,mutation |
R3290 | T13340 | T13338 | pobj | mutation,in |
R3291 | T13341 | T13340 | amod | heterozygous,mutation |
R3292 | T13342 | T13340 | amod | null,mutation |
R3293 | T13343 | T13340 | amod | similar,mutation |
R3294 | T13344 | T13343 | prep | to,similar |
R3295 | T13345 | T13344 | pobj | that,to |
R3296 | T13346 | T13345 | acl | found,that |
R3297 | T13347 | T13346 | prep | in,found |
R3298 | T13348 | T13349 | det | the,patient |
R3299 | T13349 | T13347 | pobj | patient,in |
R3300 | T13350 | T13351 | nsubj | we,report |
R3301 | T13351 | T13349 | advcl | report,patient |
R3302 | T13352 | T13327 | punct | .,result |
R3303 | T13354 | T13355 | mark | Because,is |
R3304 | T13355 | T13361 | advcl | is,suggest |
R3305 | T13356 | T13357 | det | the,mutation |
R3306 | T13463 | T13464 | advmod | more,common |
R3307 | T13464 | T13462 | amod | common,CDH |
R3308 | T13357 | T13355 | nsubj | mutation,is |
R3309 | T13465 | T13462 | compound | Bochdalek,CDH |
R3310 | T13358 | T13357 | compound | FOG2,mutation |
R3311 | T13359 | T13360 | nsubj | we,report |
R3312 | T13466 | T13452 | punct | ", ",is |
R3313 | T13360 | T13357 | advcl | report,mutation |
R3314 | T13467 | T13468 | mark | as,are |
R3315 | T13362 | T13363 | advmod | de,novo |
R3316 | T13363 | T13355 | acomp | novo,is |
R3317 | T13468 | T13452 | advcl | are,is |
R3318 | T13364 | T13355 | cc | and,is |
R3319 | T13365 | T13366 | det | the,phenotypes |
R3320 | T13469 | T13470 | det | the,mechanisms |
R3321 | T13366 | T13367 | nsubj | phenotypes,are |
R3322 | T13367 | T13355 | conj | are,is |
R3323 | T13368 | T13366 | prep | of,phenotypes |
R3324 | T13470 | T13468 | nsubj | mechanisms,are |
R3325 | T13369 | T13370 | det | the,defects |
R3326 | T13370 | T13368 | pobj | defects,of |
R3327 | T13371 | T13370 | amod | pulmonary,defects |
R3328 | T13471 | T13470 | amod | pathogenic,mechanisms |
R3329 | T13372 | T13371 | cc | and,pulmonary |
R3330 | T13373 | T13371 | conj | diaphragmatic,pulmonary |
R3331 | T13374 | T13367 | acomp | similar,are |
R3332 | T13472 | T13470 | prep | for,mechanisms |
R3333 | T13473 | T13472 | pobj | both,for |
R3334 | T13375 | T13367 | prep | between,are |
R3335 | T13474 | T13475 | advmod | largely,unknown |
R3336 | T13376 | T13375 | pobj | mouse,between |
R3337 | T13377 | T13376 | cc | and,mouse |
R3338 | T13475 | T13468 | acomp | unknown,are |
R3339 | T13378 | T13376 | conj | human,mouse |
R3340 | T13379 | T13361 | punct | ", ",suggest |
R3341 | T13476 | T13452 | punct | .,is |
R3342 | T13380 | T13361 | nsubj | we,suggest |
R3343 | T13381 | T13382 | mark | that,is |
R3344 | T13478 | T13479 | compound | Muscle,precursors |
R3345 | T13382 | T13361 | ccomp | is,suggest |
R3346 | T13383 | T13384 | det | this,mutation |
R3347 | T13384 | T13382 | nsubj | mutation,is |
R3348 | T13385 | T13384 | prep | in,mutation |
R3349 | T13479 | T13480 | nsubj | precursors,migrate |
R3350 | T13386 | T13385 | pobj | FOG2,in |
R3351 | T13387 | T13388 | det | the,cause |
R3352 | T13481 | T13479 | acl | destined,precursors |
R3353 | T13388 | T13382 | attr | cause,is |
R3354 | T13389 | T13388 | amod | first,cause |
R3355 | T13390 | T13388 | amod | reported,cause |
R3356 | T13391 | T13388 | prep | of,cause |
R3357 | T13482 | T13483 | aux | to,populate |
R3358 | T13392 | T13393 | det | a,defect |
R3359 | T13393 | T13391 | pobj | defect,of |
R3360 | T13394 | T13393 | amod | human,defect |
R3361 | T13395 | T13393 | amod | developmental,defect |
R3362 | T13396 | T13393 | amod | diaphragmatic,defect |
R3363 | T13483 | T13481 | xcomp | populate,destined |
R3364 | T13397 | T13396 | cc | and,diaphragmatic |
R3365 | T13398 | T13396 | conj | pulmonary,diaphragmatic |
R3366 | T13399 | T13361 | punct | .,suggest |
R3367 | T13484 | T13485 | det | the,diaphragm |
R3368 | T13401 | T13402 | prep | In,appear |
R3369 | T13485 | T13483 | dobj | diaphragm,populate |
R3370 | T13403 | T13401 | pobj | contrast,In |
R3371 | T13404 | T13403 | prep | to,contrast |
R3372 | T13486 | T13480 | prep | from,migrate |
R3373 | T13405 | T13406 | det | the,child |
R3374 | T13406 | T13404 | pobj | child,to |
R3375 | T13407 | T13406 | amod | affected,child |
R3376 | T13487 | T13488 | det | the,dermomyotome |
R3377 | T13408 | T13402 | punct | ", ",appear |
R3378 | T13409 | T13402 | nsubj | mice,appear |
R3379 | T13488 | T13486 | pobj | dermomyotome,from |
R3380 | T13410 | T13409 | amod | heterozygous,mice |
R3381 | T13411 | T13410 | prep | for,heterozygous |
R3382 | T13412 | T13413 | det | a,mutation |
R3383 | T13489 | T13488 | amod | lateral,dermomyotome |
R3384 | T13413 | T13411 | pobj | mutation,for |
R3385 | T13414 | T13413 | amod | null,mutation |
R3386 | T13415 | T13413 | prep | of,mutation |
R3387 | T13490 | T13488 | prep | of,dermomyotome |
R3388 | T13416 | T13415 | pobj | Fog2,of |
R3389 | T13417 | T13402 | oprd | normal,appear |
R3390 | T13491 | T13492 | amod | cervical,somites |
R3391 | T13418 | T13402 | punct | .,appear |
R3392 | T13420 | T13421 | advmod | However,is |
R3393 | T13492 | T13490 | pobj | somites,of |
R3394 | T13422 | T13421 | punct | ", ",is |
R3395 | T13493 | T13480 | punct | .,migrate |
R3396 | T13423 | T13421 | expl | there,is |
R3397 | T13424 | T13425 | amod | ample,precedent |
R3398 | T13425 | T13421 | attr | precedent,is |
R3399 | T13495 | T13496 | advmod | Prior,to |
R3400 | T13426 | T13425 | prep | for,precedent |
R3401 | T13427 | T13428 | det | the,observation |
R3402 | T13428 | T13426 | pobj | observation,for |
R3403 | T13429 | T13430 | mark | that,is |
R3404 | T13496 | T13497 | prep | to,populate |
R3405 | T13430 | T13428 | acl | is,observation |
R3406 | T13498 | T13496 | pobj | migration,to |
R3407 | T13431 | T13430 | nsubj | haploinsufficiency,is |
R3408 | T13432 | T13431 | prep | of,haploinsufficiency |
R3409 | T13433 | T13434 | det | a,gene |
R3410 | T13434 | T13432 | pobj | gene,of |
R3411 | T13435 | T13434 | prep | with,gene |
R3412 | T13436 | T13437 | amod | developmental,functions |
R3413 | T13437 | T13435 | pobj | functions,with |
R3414 | T13499 | T13498 | prep | onto,migration |
R3415 | T13438 | T13439 | advmod | much,less |
R3416 | T13439 | T13440 | advmod | less,well |
R3417 | T13440 | T13441 | advmod | well,tolerated |
R3418 | T13441 | T13430 | acomp | tolerated,is |
R3419 | T13500 | T13501 | det | the,diaphragm |
R3420 | T13442 | T13430 | prep | in,is |
R3421 | T13443 | T13442 | pobj | humans,in |
R3422 | T13501 | T13499 | pobj | diaphragm,onto |
R3423 | T13444 | T13430 | prep | than,is |
R3424 | T13445 | T13444 | pobj | mice,than |
R3425 | T13446 | T13447 | punct | [,41 |
R3426 | T13502 | T13497 | punct | ", ",populate |
R3427 | T13447 | T13421 | parataxis | 41,is |
R3428 | T13448 | T13447 | punct | ],41 |
R3429 | T13503 | T13497 | nsubj | they,populate |
R3430 | T13449 | T13421 | punct | .,is |
R3431 | T13451 | T13452 | nsubj | It,is |
R3432 | T13504 | T13505 | det | the,PPF |
R3433 | T13453 | T13452 | acomp | unclear,is |
R3434 | T13454 | T13455 | advmod | how,relates |
R3435 | T13505 | T13497 | dobj | PPF,populate |
R3436 | T13455 | T13452 | ccomp | relates,is |
R3437 | T13456 | T13457 | det | the,defect |
R3438 | T13506 | T13505 | punct | ", ",PPF |
R3439 | T13457 | T13455 | nsubj | defect,relates |
R3440 | T13458 | T13457 | nmod | Fog2,defect |
R3441 | T13459 | T13457 | amod | diaphragmatic,defect |
R3442 | T13507 | T13508 | det | a,tissue |
R3443 | T13460 | T13455 | prep | to,relates |
R3444 | T13461 | T13462 | det | the,CDH |
R3445 | T13508 | T13505 | appos | tissue,PPF |
R3446 | T13509 | T13510 | npadvmod | wedge,shaped |
R3447 | T13462 | T13460 | pobj | CDH,to |
R3448 | T13510 | T13508 | amod | shaped,tissue |
R3449 | T13511 | T13510 | punct | -,shaped |
R3450 | T13512 | T13513 | dep | that,tapers |
R3451 | T13513 | T13508 | relcl | tapers,tissue |
R3452 | T13514 | T13513 | advmod | medially,tapers |
R3453 | T13515 | T13513 | prep | from,tapers |
R3454 | T13570 | T13571 | advmod | Thus,results |
R3455 | T13516 | T13517 | det | the,wall |
R3456 | T13572 | T13571 | punct | ", ",results |
R3457 | T13517 | T13515 | pobj | wall,from |
R3458 | T13573 | T13574 | det | a,defect |
R3459 | T13574 | T13571 | nsubj | defect,results |
R3460 | T13518 | T13517 | amod | lateral,wall |
R3461 | T13575 | T13574 | prep | in,defect |
R3462 | T13576 | T13577 | compound | PPF,formation |
R3463 | T13577 | T13575 | pobj | formation,in |
R3464 | T13578 | T13571 | advmod | subsequently,results |
R3465 | T13579 | T13571 | prep | in,results |
R3466 | T13580 | T13581 | det | the,formation |
R3467 | T13519 | T13517 | compound | body,wall |
R3468 | T13581 | T13579 | pobj | formation,in |
R3469 | T13582 | T13581 | amod | abnormal,formation |
R3470 | T13583 | T13581 | prep | of,formation |
R3471 | T13520 | T13513 | prep | to,tapers |
R3472 | T13584 | T13585 | det | the,diaphragm |
R3473 | T13585 | T13583 | pobj | diaphragm,of |
R3474 | T13521 | T13522 | det | the,mesentery |
R3475 | T13586 | T13587 | punct | [,43 |
R3476 | T13587 | T13571 | parataxis | 43,results |
R3477 | T13588 | T13587 | punct | ],43 |
R3478 | T13589 | T13571 | punct | .,results |
R3479 | T13522 | T13520 | pobj | mesentery,to |
R3480 | T13591 | T13592 | nsubj | We,shown |
R3481 | T13523 | T13522 | amod | esophageal,mesentery |
R3482 | T13593 | T13592 | aux | have,shown |
R3483 | T13594 | T13595 | mark | that,have |
R3484 | T13524 | T13513 | cc | and,tapers |
R3485 | T13595 | T13592 | ccomp | have,shown |
R3486 | T13596 | T13597 | det | the,mutant |
R3487 | T13597 | T13595 | nsubj | mutant,have |
R3488 | T13525 | T13513 | conj | fuses,tapers |
R3489 | T13598 | T13597 | compound | Fog2,mutant |
R3490 | T13599 | T13595 | aux | does,have |
R3491 | T13600 | T13601 | det | an,pattern |
R3492 | T13526 | T13525 | advmod | ventrally,fuses |
R3493 | T13601 | T13595 | dobj | pattern,have |
R3494 | T13602 | T13601 | amod | abnormal,pattern |
R3495 | T13527 | T13525 | prep | with,fuses |
R3496 | T13603 | T13601 | prep | of,pattern |
R3497 | T13604 | T13605 | compound | HGF,expression |
R3498 | T13605 | T13603 | pobj | expression,of |
R3499 | T13528 | T13529 | det | the,transversum |
R3500 | T13606 | T13595 | prep | in,have |
R3501 | T13607 | T13608 | det | the,region |
R3502 | T13608 | T13606 | pobj | region,in |
R3503 | T13529 | T13527 | pobj | transversum,with |
R3504 | T13609 | T13610 | prep | through,migrate |
R3505 | T13610 | T13608 | relcl | migrate,region |
R3506 | T13611 | T13609 | pobj | which,through |
R3507 | T13530 | T13529 | compound | septum,transversum |
R3508 | T13612 | T13613 | compound | muscle,cells |
R3509 | T13613 | T13610 | nsubj | cells,migrate |
R3510 | T13531 | T13532 | punct | [,42 |
R3511 | T13614 | T13613 | compound | precursor,cells |
R3512 | T13615 | T13610 | prep | onto,migrate |
R3513 | T13616 | T13617 | det | the,diaphragm |
R3514 | T13617 | T13615 | pobj | diaphragm,onto |
R3515 | T13618 | T13617 | amod | developing,diaphragm |
R3516 | T13619 | T13592 | punct | .,shown |
R3517 | T13532 | T13497 | parataxis | 42,populate |
R3518 | T13533 | T13532 | punct | ],42 |
R3519 | T13621 | T13622 | det | This,finding |
R3520 | T13534 | T13497 | punct | .,populate |
R3521 | T13622 | T13623 | nsubj | finding,account |
R3522 | T13536 | T13537 | compound | Muscle,precursors |
R3523 | T13624 | T13623 | aux | may,account |
R3524 | T13625 | T13623 | prep | for,account |
R3525 | T13626 | T13627 | det | the,muscle |
R3526 | T13537 | T13538 | nsubj | precursors,reach |
R3527 | T13627 | T13625 | pobj | muscle,for |
R3528 | T13628 | T13629 | advmod | abnormally,patterned |
R3529 | T13629 | T13627 | amod | patterned,muscle |
R3530 | T13539 | T13540 | det | the,PPF |
R3531 | T13630 | T13631 | dep | that,develops |
R3532 | T13631 | T13627 | relcl | develops,muscle |
R3533 | T13632 | T13631 | prep | in,develops |
R3534 | T13633 | T13634 | det | the,diaphragm |
R3535 | T13540 | T13538 | dobj | PPF,reach |
R3536 | T13541 | T13538 | prep | by,reach |
R3537 | T13634 | T13632 | pobj | diaphragm,in |
R3538 | T13542 | T13541 | pobj | E11,by |
R3539 | T13635 | T13636 | compound | Fog2,mutant |
R3540 | T13636 | T13634 | compound | mutant,diaphragm |
R3541 | T13637 | T13623 | punct | .,account |
R3542 | T13543 | T13538 | punct | ", ",reach |
R3543 | T13639 | T13640 | mark | Although,detected |
R3544 | T13544 | T13545 | advmod | where,proliferate |
R3545 | T13640 | T13646 | advcl | detected,need |
R3546 | T13641 | T13642 | nmod | Pax3,expression |
R3547 | T13642 | T13640 | nsubjpass | expression,detected |
R3548 | T13545 | T13538 | ccomp | proliferate,reach |
R3549 | T13643 | T13641 | cc | and,Pax3 |
R3550 | T13546 | T13545 | nsubj | they,proliferate |
R3551 | T13644 | T13641 | conj | MyoD,Pax3 |
R3552 | T13547 | T13545 | punct | ", ",proliferate |
R3553 | T13645 | T13640 | auxpass | is,detected |
R3554 | T13548 | T13545 | conj | differentiate,proliferate |
R3555 | T13647 | T13640 | prep | in,detected |
R3556 | T13648 | T13649 | det | the,PPF |
R3557 | T13649 | T13647 | pobj | PPF,in |
R3558 | T13549 | T13548 | punct | ", ",differentiate |
R3559 | T13650 | T13646 | punct | ", ",need |
R3560 | T13651 | T13652 | det | a,analysis |
R3561 | T13652 | T13646 | nsubj | analysis,need |
R3562 | T13550 | T13548 | cc | and,differentiate |
R3563 | T13653 | T13652 | amod | detailed,analysis |
R3564 | T13654 | T13652 | prep | of,analysis |
R3565 | T13655 | T13656 | compound | transcription,factors |
R3566 | T13656 | T13654 | pobj | factors,of |
R3567 | T13657 | T13656 | amod | responsible,factors |
R3568 | T13658 | T13657 | prep | for,responsible |
R3569 | T13551 | T13552 | advmod | then,migrate |
R3570 | T13659 | T13660 | compound | muscle,cell |
R3571 | T13660 | T13658 | pobj | cell,for |
R3572 | T13661 | T13660 | compound | precursor,cell |
R3573 | T13662 | T13660 | appos | migration,cell |
R3574 | T13552 | T13548 | conj | migrate,differentiate |
R3575 | T13663 | T13662 | cc | and,migration |
R3576 | T13664 | T13662 | conj | differentiation,migration |
R3577 | T13553 | T13552 | prep | toward,migrate |
R3578 | T13665 | T13646 | aux | will,need |
R3579 | T13666 | T13667 | aux | to,completed |
R3580 | T13667 | T13646 | xcomp | completed,need |
R3581 | T13554 | T13555 | det | the,regions |
R3582 | T13668 | T13667 | auxpass | be,completed |
R3583 | T13669 | T13670 | preconj | both,in |
R3584 | T13670 | T13667 | prep | in,completed |
R3585 | T13555 | T13553 | pobj | regions,toward |
R3586 | T13671 | T13672 | det | the,PPF |
R3587 | T13672 | T13670 | pobj | PPF,in |
R3588 | T13556 | T13557 | amod | dorsolateral,costal |
R3589 | T13673 | T13670 | cc | and,in |
R3590 | T13674 | T13670 | conj | along,in |
R3591 | T13557 | T13555 | amod | costal,regions |
R3592 | T13558 | T13557 | punct | ", ",costal |
R3593 | T13559 | T13560 | amod | sternal,costal |
R3594 | T13560 | T13557 | conj | costal,costal |
R3595 | T13561 | T13560 | punct | ", ",costal |
R3596 | T13675 | T13676 | det | the,pathway |
R3597 | T13676 | T13674 | pobj | pathway,along |
R3598 | T13677 | T13676 | prep | of,pathway |
R3599 | T13562 | T13560 | cc | and,costal |
R3600 | T13678 | T13679 | compound | muscle,cell |
R3601 | T13679 | T13681 | compound | cell,migration |
R3602 | T13680 | T13679 | compound | precursor,cell |
R3603 | T13563 | T13560 | conj | crural,costal |
R3604 | T13681 | T13677 | pobj | migration,of |
R3605 | T13682 | T13676 | prep | between,pathway |
R3606 | T13564 | T13555 | prep | of,regions |
R3607 | T13683 | T13684 | det | the,PPF |
R3608 | T13684 | T13682 | pobj | PPF,between |
R3609 | T13685 | T13684 | cc | and,PPF |
R3610 | T13565 | T13566 | det | the,diaphragm |
R3611 | T13686 | T13687 | det | the,diaphragm |
R3612 | T13687 | T13684 | conj | diaphragm,PPF |
R3613 | T13688 | T13687 | amod | membranous,diaphragm |
R3614 | T13566 | T13564 | pobj | diaphragm,of |
R3615 | T13689 | T13646 | punct | .,need |
R3616 | T13691 | T13692 | nsubj | Fog2,interact |
R3617 | T13567 | T13566 | amod | developing,diaphragm |
R3618 | T13693 | T13692 | aux | can,interact |
R3619 | T13694 | T13692 | prep | with,interact |
R3620 | T13695 | T13694 | pobj | any,with |
R3621 | T13696 | T13695 | prep | of,any |
R3622 | T13697 | T13698 | det | the,factors |
R3623 | T13568 | T13538 | punct | .,reach |
R3624 | T13698 | T13696 | pobj | factors,of |
R3625 | T13699 | T13698 | compound | Gata,factors |
R3626 | T13700 | T13695 | punct | ", ",any |
R3627 | T13701 | T13702 | nmod | Gatas,1 |
R3628 | T13781 | T13780 | prep | with,associated |
R3629 | T13702 | T13695 | appos | 1,any |
R3630 | T13703 | T13704 | punct | –,6 |
R3631 | T13704 | T13702 | prep | 6,1 |
R3632 | T13705 | T13695 | punct | ", ",any |
R3633 | T13782 | T13783 | amod | abnormal,anatomy |
R3634 | T13706 | T13707 | advmod | as,as |
R3635 | T13707 | T13695 | cc | as,any |
R3636 | T13708 | T13707 | advmod | well,as |
R3637 | T13783 | T13781 | pobj | anatomy,with |
R3638 | T13709 | T13710 | amod | other,factors |
R3639 | T13710 | T13695 | conj | factors,any |
R3640 | T13711 | T13710 | compound | transcription,factors |
R3641 | T13784 | T13783 | amod | diaphragmatic,anatomy |
R3642 | T13712 | T13713 | amod | such,as |
R3643 | T13713 | T13710 | prep | as,factors |
R3644 | T13714 | T13713 | pobj | CoupTFII,as |
R3645 | T13785 | T13783 | cc | or,anatomy |
R3646 | T13715 | T13716 | punct | [,45 |
R3647 | T13716 | T13692 | parataxis | 45,interact |
R3648 | T13717 | T13716 | nummod | 44,45 |
R3649 | T13786 | T13783 | conj | function,anatomy |
R3650 | T13718 | T13716 | punct | ",",45 |
R3651 | T13719 | T13716 | punct | ],45 |
R3652 | T13787 | T13779 | punct | ", ",is |
R3653 | T13720 | T13692 | punct | .,interact |
R3654 | T13788 | T13779 | cc | and,is |
R3655 | T13722 | T13723 | nsubjpass | It,known |
R3656 | T13789 | T13790 | auxpass | is,known |
R3657 | T13724 | T13723 | auxpass | is,known |
R3658 | T13790 | T13779 | conj | known,is |
R3659 | T13725 | T13726 | mark | that,is |
R3660 | T13726 | T13723 | ccomp | is,known |
R3661 | T13727 | T13728 | det | a,interaction |
R3662 | T13791 | T13792 | aux | to,occur |
R3663 | T13728 | T13726 | nsubj | interaction,is |
R3664 | T13729 | T13730 | compound | Fog2,Gata4 |
R3665 | T13792 | T13790 | xcomp | occur,known |
R3666 | T13730 | T13728 | compound | Gata4,interaction |
R3667 | T13731 | T13730 | punct | –,Gata4 |
R3668 | T13732 | T13726 | acomp | critical,is |
R3669 | T13793 | T13792 | prep | as,occur |
R3670 | T13733 | T13732 | prep | for,critical |
R3671 | T13734 | T13735 | amod | normal,development |
R3672 | T13735 | T13733 | pobj | development,for |
R3673 | T13736 | T13735 | amod | cardiac,development |
R3674 | T13737 | T13736 | cc | and,cardiac |
R3675 | T13738 | T13736 | conj | gonadal,cardiac |
R3676 | T13794 | T13795 | det | a,defect |
R3677 | T13739 | T13723 | punct | ", ",known |
R3678 | T13740 | T13723 | cc | but,known |
R3679 | T13741 | T13742 | amod | interacting,factors |
R3680 | T13795 | T13793 | pobj | defect,as |
R3681 | T13742 | T13743 | nsubjpass | factors,determined |
R3682 | T13743 | T13723 | conj | determined,known |
R3683 | T13744 | T13742 | prep | in,factors |
R3684 | T13796 | T13795 | amod | secondary,defect |
R3685 | T13745 | T13746 | det | the,lung |
R3686 | T13746 | T13744 | pobj | lung,in |
R3687 | T13747 | T13746 | cc | and,lung |
R3688 | T13797 | T13795 | amod | developmental,defect |
R3689 | T13748 | T13746 | conj | diaphragm,lung |
R3690 | T13749 | T13743 | aux | have,determined |
R3691 | T13750 | T13743 | neg | not,determined |
R3692 | T13798 | T13792 | prep | in,occur |
R3693 | T13751 | T13743 | advmod | yet,determined |
R3694 | T13752 | T13743 | auxpass | been,determined |
R3695 | T13799 | T13798 | pobj | models,in |
R3696 | T13753 | T13743 | punct | .,determined |
R3697 | T13755 | T13756 | det | The,severity |
R3698 | T13800 | T13799 | prep | of,models |
R3699 | T13756 | T13757 | nsubj | severity,was |
R3700 | T13801 | T13802 | amod | diaphragmatic,dysfunction |
R3701 | T13758 | T13756 | prep | of,severity |
R3702 | T13759 | T13760 | amod | pulmonary,hypoplasia |
R3703 | T13760 | T13758 | pobj | hypoplasia,of |
R3704 | T13761 | T13756 | prep | in,severity |
R3705 | T13802 | T13800 | pobj | dysfunction,of |
R3706 | T13762 | T13763 | det | the,patient |
R3707 | T13763 | T13761 | pobj | patient,in |
R3708 | T13803 | T13804 | amod | such,as |
R3709 | T13764 | T13765 | nsubj | we,report |
R3710 | T13765 | T13763 | advcl | report,patient |
R3711 | T13766 | T13757 | prep | out,was |
R3712 | T13767 | T13766 | prep | of,out |
R3713 | T13804 | T13802 | prep | as,dysfunction |
R3714 | T13768 | T13767 | pobj | proportion,of |
R3715 | T13769 | T13768 | prep | to,proportion |
R3716 | T13805 | T13806 | amod | complete,amuscularization |
R3717 | T13770 | T13769 | pobj | that,to |
R3718 | T13771 | T13770 | prep | of,that |
R3719 | T13772 | T13773 | det | the,defect |
R3720 | T13806 | T13804 | pobj | amuscularization,as |
R3721 | T13773 | T13771 | pobj | defect,of |
R3722 | T13774 | T13773 | compound | diaphragm,defect |
R3723 | T13775 | T13757 | punct | .,was |
R3724 | T13777 | T13778 | amod | Pulmonary,hypoplasia |
R3725 | T13807 | T13808 | punct | [,17 |
R3726 | T13778 | T13779 | nsubj | hypoplasia,is |
R3727 | T13780 | T13779 | acomp | associated,is |
R3728 | T13808 | T13806 | parataxis | 17,amuscularization |
R3729 | T13809 | T13808 | punct | ],17 |
R3730 | T13810 | T13806 | cc | or,amuscularization |
R3731 | T13887 | T13884 | agent | by,suspected |
R3732 | T13888 | T13887 | pobj | clinicians,by |
R3733 | T13811 | T13812 | amod | phrenic,nerve |
R3734 | T13889 | T13890 | dep | who,care |
R3735 | T13890 | T13888 | relcl | care,clinicians |
R3736 | T13891 | T13890 | prep | for,care |
R3737 | T13812 | T13813 | compound | nerve,disruption |
R3738 | T13892 | T13893 | det | these,patients |
R3739 | T13813 | T13806 | conj | disruption,amuscularization |
R3740 | T13814 | T13815 | punct | [,46 |
R3741 | T13815 | T13813 | parataxis | 46,disruption |
R3742 | T13893 | T13891 | pobj | patients,for |
R3743 | T13894 | T13847 | punct | .,suggested |
R3744 | T13816 | T13815 | punct | ],46 |
R3745 | T13896 | T13897 | prep | In,supports |
R3746 | T13817 | T13779 | punct | .,is |
R3747 | T13898 | T13896 | pobj | addition,In |
R3748 | T13899 | T13897 | punct | ", ",supports |
R3749 | T13900 | T13901 | det | the,incidence |
R3750 | T13819 | T13820 | nsubj | It,occurs |
R3751 | T13901 | T13897 | nsubj | incidence,supports |
R3752 | T13902 | T13901 | amod | high,incidence |
R3753 | T13903 | T13901 | prep | of,incidence |
R3754 | T13821 | T13820 | prep | in,occurs |
R3755 | T13904 | T13905 | compound | lobar,abnormalities |
R3756 | T13905 | T13903 | pobj | abnormalities,of |
R3757 | T13906 | T13905 | amod | associated,abnormalities |
R3758 | T13907 | T13906 | prep | with,associated |
R3759 | T13822 | T13823 | det | a,model |
R3760 | T13908 | T13907 | pobj | CDH,with |
R3761 | T13909 | T13910 | punct | [,52 |
R3762 | T13910 | T13901 | parataxis | 52,incidence |
R3763 | T13823 | T13821 | pobj | model,in |
R3764 | T13911 | T13910 | punct | ],52 |
R3765 | T13912 | T13913 | det | the,possibility |
R3766 | T13913 | T13897 | dobj | possibility,supports |
R3767 | T13824 | T13823 | amod | surgical,model |
R3768 | T13914 | T13915 | mark | that,associated |
R3769 | T13915 | T13913 | acl | associated,possibility |
R3770 | T13825 | T13823 | prep | of,model |
R3771 | T13916 | T13917 | det | this,disorder |
R3772 | T13917 | T13915 | nsubjpass | disorder,associated |
R3773 | T13918 | T13915 | aux | can,associated |
R3774 | T13919 | T13915 | auxpass | be,associated |
R3775 | T13920 | T13915 | prep | with,associated |
R3776 | T13921 | T13922 | det | a,abnormality |
R3777 | T13826 | T13825 | pobj | CDH,of |
R3778 | T13922 | T13920 | pobj | abnormality,with |
R3779 | T13923 | T13922 | amod | primary,abnormality |
R3780 | T13924 | T13922 | amod | developmental,abnormality |
R3781 | T13827 | T13828 | prep | in,created |
R3782 | T13925 | T13922 | amod | pulmonary,abnormality |
R3783 | T13926 | T13897 | punct | .,supports |
R3784 | T13828 | T13823 | relcl | created,model |
R3785 | T13928 | T13929 | poss | Our,analysis |
R3786 | T13929 | T13930 | nsubj | analysis,proves |
R3787 | T13829 | T13827 | pobj | which,in |
R3788 | T13931 | T13929 | prep | of,analysis |
R3789 | T13932 | T13931 | pobj | mice,of |
R3790 | T13830 | T13831 | det | a,hernia |
R3791 | T13933 | T13932 | acl | carrying,mice |
R3792 | T13934 | T13933 | dobj | mutations,carrying |
R3793 | T13935 | T13934 | prep | of,mutations |
R3794 | T13831 | T13828 | nsubjpass | hernia,created |
R3795 | T13936 | T13935 | pobj | Fog2,of |
R3796 | T13937 | T13938 | mark | that,is |
R3797 | T13938 | T13930 | ccomp | is,proves |
R3798 | T13832 | T13828 | auxpass | is,created |
R3799 | T13939 | T13938 | expl | there,is |
R3800 | T13940 | T13941 | det | a,defect |
R3801 | T13833 | T13828 | advmod | physically,created |
R3802 | T13941 | T13938 | attr | defect,is |
R3803 | T13942 | T13941 | amod | primary,defect |
R3804 | T13943 | T13941 | prep | in,defect |
R3805 | T13944 | T13945 | compound | lung,development |
R3806 | T13834 | T13828 | prep | in,created |
R3807 | T13945 | T13943 | pobj | development,in |
R3808 | T13946 | T13947 | dep | that,results |
R3809 | T13947 | T13941 | relcl | results,defect |
R3810 | T13835 | T13836 | det | an,lamb |
R3811 | T13948 | T13947 | prep | in,results |
R3812 | T13949 | T13950 | amod | specific,loss |
R3813 | T13950 | T13948 | pobj | loss,in |
R3814 | T13836 | T13834 | pobj | lamb,in |
R3815 | T13951 | T13950 | prep | of,loss |
R3816 | T13952 | T13953 | det | the,lobe |
R3817 | T13953 | T13951 | pobj | lobe,of |
R3818 | T13837 | T13838 | advmod | in,utero |
R3819 | T13954 | T13953 | amod | accessory,lobe |
R3820 | T13955 | T13950 | cc | and,loss |
R3821 | T13956 | T13957 | amod | partial,loss |
R3822 | T13838 | T13836 | amod | utero,lamb |
R3823 | T13957 | T13950 | conj | loss,loss |
R3824 | T13958 | T13957 | prep | of,loss |
R3825 | T13959 | T13960 | det | the,lobe |
R3826 | T13960 | T13958 | pobj | lobe,of |
R3827 | T13961 | T13960 | amod | right,lobe |
R3828 | T13839 | T13840 | punct | [,48 |
R3829 | T13962 | T13960 | amod | middle,lobe |
R3830 | T13963 | T13930 | punct | .,proves |
R3831 | T13840 | T13820 | parataxis | 48,occurs |
R3832 | T13965 | T13966 | det | The,defects |
R3833 | T13966 | T13969 | nsubj | defects,prompted |
R3834 | T13967 | T13966 | amod | specific,defects |
R3835 | T13841 | T13840 | nummod | 47,48 |
R3836 | T13968 | T13966 | compound | lobar,defects |
R3837 | T13970 | T13969 | dobj | us,prompted |
R3838 | T13971 | T13972 | aux | to,evaluate |
R3839 | T13842 | T13840 | punct | ",",48 |
R3840 | T13972 | T13969 | xcomp | evaluate,prompted |
R3841 | T13973 | T13974 | compound | Fog2,expression |
R3842 | T13843 | T13840 | punct | ],48 |
R3843 | T13974 | T13972 | dobj | expression,evaluate |
R3844 | T13975 | T13972 | prep | at,evaluate |
R3845 | T13976 | T13977 | det | the,time |
R3846 | T13844 | T13820 | punct | .,occurs |
R3847 | T13977 | T13975 | pobj | time,at |
R3848 | T13978 | T13977 | prep | of,time |
R3849 | T13979 | T13980 | amod | early,budding |
R3850 | T13846 | T13847 | advmod | However,suggested |
R3851 | T13980 | T13978 | pobj | budding,of |
R3852 | T13848 | T13847 | punct | ", ",suggested |
R3853 | T13981 | T13980 | compound | lobar,budding |
R3854 | T13982 | T13969 | punct | .,prompted |
R3855 | T13849 | T13850 | det | the,possibility |
R3856 | T13984 | T13985 | mark | While,is |
R3857 | T13985 | T13988 | advcl | is,expressed |
R3858 | T13986 | T13987 | compound | Fog2,expression |
R3859 | T13850 | T13847 | nsubjpass | possibility,suggested |
R3860 | T13987 | T13985 | nsubj | expression,is |
R3861 | T13989 | T13985 | acomp | diffuse,is |
R3862 | T13851 | T13852 | mark | that,occur |
R3863 | T13990 | T13985 | prep | in,is |
R3864 | T13991 | T13992 | det | the,mesenchyme |
R3865 | T13992 | T13990 | pobj | mesenchyme,in |
R3866 | T13852 | T13850 | acl | occur,possibility |
R3867 | T13853 | T13854 | amod | primary,abnormalities |
R3868 | T13854 | T13852 | nsubj | abnormalities,occur |
R3869 | T13993 | T13992 | amod | pulmonary,mesenchyme |
R3870 | T13994 | T13995 | mark | after,is |
R3871 | T13855 | T13854 | amod | pulmonary,abnormalities |
R3872 | T13995 | T13985 | advcl | is,is |
R3873 | T13996 | T13997 | compound | lobar,structure |
R3874 | T13856 | T13854 | amod | developmental,abnormalities |
R3875 | T13997 | T13995 | nsubj | structure,is |
R3876 | T13998 | T13999 | advmod | well,established |
R3877 | T13999 | T13995 | acomp | established,is |
R3878 | T14000 | T14001 | punct | (,E12.5 |
R3879 | T14001 | T13995 | parataxis | E12.5,is |
R3880 | T14002 | T14001 | punct | ),E12.5 |
R3881 | T13857 | T13852 | prep | with,occur |
R3882 | T14003 | T13988 | punct | ", ",expressed |
R3883 | T14004 | T13988 | nsubjpass | it,expressed |
R3884 | T14005 | T13988 | auxpass | is,expressed |
R3885 | T13858 | T13857 | punct | ", ",with |
R3886 | T14006 | T14007 | advmod | more,focally |
R3887 | T14007 | T13988 | advmod | focally,expressed |
R3888 | T14008 | T13988 | prep | in,expressed |
R3889 | T13859 | T13860 | advmod | rather,than |
R3890 | T14009 | T14010 | det | the,mesenchyme |
R3891 | T13860 | T13857 | cc | than,with |
R3892 | T13861 | T13857 | advmod | secondary,with |
R3893 | T14010 | T14008 | pobj | mesenchyme,in |
R3894 | T14011 | T14010 | acl | surrounding,mesenchyme |
R3895 | T13862 | T13861 | prep | to,secondary |
R3896 | T14012 | T14013 | det | the,lobe |
R3897 | T14013 | T14011 | dobj | lobe,surrounding |
R3898 | T13863 | T13857 | punct | ", ",with |
R3899 | T14014 | T14013 | amod | right,lobe |
R3900 | T14015 | T14013 | amod | middle,lobe |
R3901 | T14016 | T14013 | cc | and,lobe |
R3902 | T13864 | T13865 | amod | diaphragmatic,defects |
R3903 | T14017 | T14018 | amod | accessory,buds |
R3904 | T14018 | T14013 | conj | buds,lobe |
R3905 | T14019 | T14020 | mark | as,form |
R3906 | T13865 | T13857 | conj | defects,with |
R3907 | T14020 | T13988 | advcl | form,expressed |
R3908 | T14021 | T14022 | det | these,lobes |
R3909 | T13866 | T13847 | aux | has,suggested |
R3910 | T14022 | T14020 | nsubj | lobes,form |
R3911 | T14023 | T13988 | punct | .,expressed |
R3912 | T13867 | T13847 | auxpass | been,suggested |
R3913 | T14025 | T14026 | nsubj | This,matches |
R3914 | T13868 | T13847 | agent | by,suggested |
R3915 | T14027 | T14028 | det | the,phenotype |
R3916 | T14028 | T14026 | dobj | phenotype,matches |
R3917 | T14029 | T14028 | prep | of,phenotype |
R3918 | T13869 | T13868 | pobj | others,by |
R3919 | T14030 | T14031 | amod | right,lobe |
R3920 | T14031 | T14033 | nmod | lobe,loss |
R3921 | T14032 | T14031 | amod | middle,lobe |
R3922 | T13870 | T13847 | prep | based,suggested |
R3923 | T14033 | T14029 | pobj | loss,of |
R3924 | T14034 | T14031 | cc | and,lobe |
R3925 | T14035 | T14036 | amod | accessory,lobe |
R3926 | T13871 | T13870 | prep | on,based |
R3927 | T14036 | T14031 | conj | lobe,lobe |
R3928 | T14037 | T14026 | punct | ", ",matches |
R3929 | T14038 | T14026 | cc | and,matches |
R3930 | T14039 | T14026 | conj | suggests,matches |
R3931 | T14040 | T14041 | mark | that,has |
R3932 | T14041 | T14039 | ccomp | has,suggests |
R3933 | T13872 | T13873 | det | a,model |
R3934 | T14042 | T14041 | nsubj | Fog2,has |
R3935 | T14043 | T14044 | det | a,role |
R3936 | T14044 | T14041 | dobj | role,has |
R3937 | T13873 | T13871 | pobj | model,on |
R3938 | T14045 | T14044 | amod | specific,role |
R3939 | T14046 | T14044 | compound | patterning,role |
R3940 | T14047 | T14044 | prep | in,role |
R3941 | T13874 | T13873 | amod | teratogenic,model |
R3942 | T14048 | T14047 | pobj | establishment,in |
R3943 | T14049 | T14048 | prep | of,establishment |
R3944 | T14050 | T14051 | det | these,lobes |
R3945 | T13875 | T13873 | prep | of,model |
R3946 | T14051 | T14049 | pobj | lobes,of |
R3947 | T14052 | T14026 | punct | .,matches |
R3948 | T13876 | T13875 | pobj | CDH,of |
R3949 | T14054 | T14055 | nsubj | It,is |
R3950 | T13877 | T13878 | punct | [,49 |
R3951 | T14056 | T14057 | advmod | less,clear |
R3952 | T14057 | T14055 | acomp | clear,is |
R3953 | T14058 | T14059 | mark | whether,results |
R3954 | T13878 | T13847 | parataxis | 49,suggested |
R3955 | T14059 | T14055 | ccomp | results,is |
R3956 | T14060 | T14059 | nsubj | loss,results |
R3957 | T14061 | T14060 | prep | of,loss |
R3958 | T13879 | T13880 | punct | –,51 |
R3959 | T14062 | T14061 | pobj | Fog2,of |
R3960 | T14063 | T14059 | prep | in,results |
R3961 | T13880 | T13878 | prep | 51,49 |
R3962 | T14064 | T14065 | det | a,defect |
R3963 | T13881 | T13878 | punct | ],49 |
R3964 | T14065 | T14063 | pobj | defect,in |
R3965 | T13882 | T13847 | cc | and,suggested |
R3966 | T14066 | T14065 | amod | global,defect |
R3967 | T13883 | T13884 | aux | has,suspected |
R3968 | T14067 | T14065 | compound | branching,defect |
R3969 | T14068 | T14055 | punct | ", ",is |
R3970 | T14069 | T14070 | mark | as,appear |
R3971 | T13884 | T13847 | conj | suspected,suggested |
R3972 | T14070 | T14055 | advcl | appear,is |
R3973 | T14071 | T14072 | compound | Fog2,lungs |
R3974 | T14072 | T14070 | nsubj | lungs,appear |
R3975 | T13885 | T13884 | advmod | long,suspected |
R3976 | T14073 | T14074 | aux | to,have |
R3977 | T14074 | T14070 | xcomp | have,appear |
R3978 | T13886 | T13884 | auxpass | been,suspected |
R3979 | T14075 | T14076 | det | a,delay |
R3980 | T14076 | T14074 | dobj | delay,have |
R3981 | T14099 | T14097 | pobj | lobes,in |
R3982 | T14077 | T14076 | amod | slight,delay |
R3983 | T14078 | T14076 | amod | developmental,delay |
R3984 | T14079 | T14076 | punct | ", ",delay |
R3985 | T14080 | T14081 | dep | which,result |
R3986 | T14081 | T14076 | relcl | result,delay |
R3987 | T14082 | T14081 | aux | could,result |
R3988 | T14083 | T14081 | prep | from,result |
R3989 | T14100 | T14099 | amod | unaffected,lobes |
R3990 | T14084 | T14085 | amod | many,causes |
R3991 | T14085 | T14083 | pobj | causes,from |
R3992 | T14086 | T14055 | punct | .,is |
R3993 | T14101 | T14102 | dep | that,appears |
R3994 | T14088 | T14089 | amod | Cultured,lungs |
R3995 | T14089 | T14091 | nsubj | lungs,develop |
R3996 | T14090 | T14089 | compound | Fog2,lungs |
R3997 | T14102 | T14094 | relcl | appears,pattern |
R3998 | T14092 | T14091 | aux | do,develop |
R3999 | T14093 | T14094 | det | an,pattern |
R4000 | T14103 | T14102 | oprd | similar,appears |
R4001 | T14094 | T14091 | dobj | pattern,develop |
R4002 | T14095 | T14094 | amod | intricate,pattern |
R4003 | T14096 | T14094 | compound | branching,pattern |
R4004 | T14104 | T14103 | prep | in,similar |
R4005 | T14097 | T14094 | prep | in,pattern |
R4006 | T14098 | T14099 | det | the,lobes |
R4007 | T14105 | T14106 | det | the,pattern |
R4008 | T14106 | T14104 | pobj | pattern,in |
R4009 | T14107 | T14103 | prep | to,similar |
R4010 | T14108 | T14109 | amod | wild,type |
R4011 | T14206 | T14207 | nsubj | It,is |
R4012 | T14109 | T14111 | compound | type,lungs |
R4013 | T14208 | T14209 | advmod | only,as |
R4014 | T14209 | T14207 | prep | as,is |
R4015 | T14110 | T14109 | punct | -,type |
R4016 | T14210 | T14211 | det | a,consequence |
R4017 | T14211 | T14209 | pobj | consequence,as |
R4018 | T14212 | T14211 | prep | of,consequence |
R4019 | T14111 | T14107 | pobj | lungs,to |
R4020 | T14213 | T14214 | npadvmod | phenotype,driven |
R4021 | T14214 | T14216 | amod | driven,analyses |
R4022 | T14215 | T14214 | punct | -,driven |
R4023 | T14112 | T14091 | prep | after,develop |
R4024 | T14216 | T14212 | pobj | analyses,of |
R4025 | T14217 | T14218 | amod | such,as |
R4026 | T14218 | T14216 | prep | as,analyses |
R4027 | T14113 | T14114 | nummod | 5,d |
R4028 | T14219 | T14218 | pobj | those,as |
R4029 | T14220 | T14221 | nsubj | we,pursuing |
R4030 | T14221 | T14219 | advcl | pursuing,those |
R4031 | T14114 | T14112 | pobj | d,after |
R4032 | T14222 | T14221 | aux | are,pursuing |
R4033 | T14223 | T14224 | mark | that,has |
R4034 | T14224 | T14207 | ccomp | has,is |
R4035 | T14225 | T14224 | nsubj | one,has |
R4036 | T14226 | T14227 | det | the,opportunity |
R4037 | T14115 | T14114 | prep | in,d |
R4038 | T14227 | T14224 | dobj | opportunity,has |
R4039 | T14228 | T14229 | aux | to,assay |
R4040 | T14229 | T14227 | acl | assay,opportunity |
R4041 | T14230 | T14229 | dobj | all,assay |
R4042 | T14116 | T14115 | pobj | culture,in |
R4043 | T14231 | T14230 | prep | of,all |
R4044 | T14232 | T14233 | det | the,derangements |
R4045 | T14233 | T14231 | pobj | derangements,of |
R4046 | T14117 | T14091 | punct | .,develop |
R4047 | T14234 | T14233 | amod | potential,derangements |
R4048 | T14235 | T14233 | amod | molecular,derangements |
R4049 | T14119 | T14120 | prep | In,show |
R4050 | T14236 | T14237 | dep | that,result |
R4051 | T14237 | T14233 | relcl | result,derangements |
R4052 | T14238 | T14237 | aux | may,result |
R4053 | T14121 | T14122 | det | this,report |
R4054 | T14239 | T14237 | prep | in,result |
R4055 | T14240 | T14241 | amod | human,disease |
R4056 | T14122 | T14119 | pobj | report,In |
R4057 | T14241 | T14239 | pobj | disease,in |
R4058 | T14242 | T14207 | punct | .,is |
R4059 | T14123 | T14120 | punct | ", ",show |
R4060 | T14124 | T14120 | nsubj | we,show |
R4061 | T14125 | T14126 | mark | that,causes |
R4062 | T14126 | T14120 | ccomp | causes,show |
R4063 | T14127 | T14128 | det | a,mutation |
R4064 | T14128 | T14126 | nsubj | mutation,causes |
R4065 | T14129 | T14128 | prep | of,mutation |
R4066 | T14130 | T14129 | pobj | Fog2,of |
R4067 | T14131 | T14128 | prep | in,mutation |
R4068 | T14132 | T14133 | det | the,mouse |
R4069 | T14133 | T14131 | pobj | mouse,in |
R4070 | T14134 | T14135 | det | the,phenotype |
R4071 | T14135 | T14126 | dobj | phenotype,causes |
R4072 | T14136 | T14135 | prep | of,phenotype |
R4073 | T14137 | T14138 | amod | abnormal,muscularization |
R4074 | T14138 | T14136 | pobj | muscularization,of |
R4075 | T14139 | T14138 | amod | diaphragmatic,muscularization |
R4076 | T14140 | T14138 | cc | and,muscularization |
R4077 | T14141 | T14142 | amod | primary,hypoplasia |
R4078 | T14142 | T14138 | conj | hypoplasia,muscularization |
R4079 | T14143 | T14142 | amod | pulmonary,hypoplasia |
R4080 | T14144 | T14120 | punct | .,show |
R4081 | T14146 | T14147 | nsubj | We,demonstrate |
R4082 | T14148 | T14147 | advmod | furthermore,demonstrate |
R4083 | T14149 | T14150 | mark | that,is |
R4084 | T14150 | T14147 | ccomp | is,demonstrate |
R4085 | T14151 | T14152 | det | a,mutation |
R4086 | T14152 | T14150 | nsubj | mutation,is |
R4087 | T14153 | T14152 | prep | in,mutation |
R4088 | T14154 | T14155 | det | this,gene |
R4089 | T14155 | T14153 | pobj | gene,in |
R4090 | T14156 | T14150 | acomp | associated,is |
R4091 | T14157 | T14156 | prep | with,associated |
R4092 | T14158 | T14159 | det | a,defect |
R4093 | T14159 | T14157 | pobj | defect,with |
R4094 | T14160 | T14159 | amod | lethal,defect |
R4095 | T14161 | T14159 | prep | in,defect |
R4096 | T14162 | T14163 | nmod | lung,development |
R4097 | T14163 | T14161 | pobj | development,in |
R4098 | T14164 | T14162 | cc | and,lung |
R4099 | T14165 | T14162 | conj | diaphragm,lung |
R4100 | T14166 | T14159 | prep | in,defect |
R4101 | T14167 | T14168 | det | a,child |
R4102 | T14168 | T14166 | pobj | child,in |
R4103 | T14169 | T14147 | punct | .,demonstrate |
R4104 | T14171 | T14172 | nsubj | It,is |
R4105 | T14173 | T14172 | acomp | notable,is |
R4106 | T14174 | T14175 | mark | that,recognized |
R4107 | T14175 | T14172 | ccomp | recognized,is |
R4108 | T14176 | T14175 | punct | ", ",recognized |
R4109 | T14177 | T14175 | prep | despite,recognized |
R4110 | T14178 | T14179 | amod | extensive,analysis |
R4111 | T14179 | T14177 | pobj | analysis,despite |
R4112 | T14180 | T14179 | prep | of,analysis |
R4113 | T14181 | T14182 | compound | Fog2,biology |
R4114 | T14182 | T14180 | pobj | biology,of |
R4115 | T14183 | T14179 | cc | and,analysis |
R4116 | T14184 | T14185 | det | the,generation |
R4117 | T14185 | T14179 | conj | generation,analysis |
R4118 | T14186 | T14185 | prep | of,generation |
R4119 | T14187 | T14188 | det | a,mouse |
R4120 | T14188 | T14186 | pobj | mouse,of |
R4121 | T14189 | T14188 | nmod | Fog2,mouse |
R4122 | T14190 | T14188 | amod | knock,mouse |
R4123 | T14191 | T14190 | punct | -,knock |
R4124 | T14192 | T14190 | prt | out,knock |
R4125 | T14193 | T14175 | punct | ", ",recognized |
R4126 | T14194 | T14195 | poss | its,role |
R4127 | T14195 | T14175 | nsubjpass | role,recognized |
R4128 | T14196 | T14195 | prep | in,role |
R4129 | T14197 | T14198 | nmod | diaphragm,development |
R4130 | T14198 | T14196 | pobj | development,in |
R4131 | T14199 | T14197 | cc | and,diaphragm |
R4132 | T14200 | T14197 | conj | lung,diaphragm |
R4133 | T14201 | T14175 | auxpass | was,recognized |
R4134 | T14202 | T14175 | advmod | previously,recognized |
R4135 | T14203 | T14175 | neg | not,recognized |
R4136 | T14204 | T14172 | punct | .,is |
R4137 | T14396 | T14397 | amod | Genetic,mapping |
R4138 | T14398 | T14397 | prep | of,mapping |
R4139 | T14399 | T14400 | det | the,mutation |
R4140 | T14400 | T14398 | pobj | mutation,of |
R4141 | T14401 | T14400 | compound | mouse,mutation |
R4142 | T14402 | T14400 | appos | lil,mutation |
R4143 | T14403 | T14397 | punct | .,mapping |
R4144 | T14405 | T14406 | det | The,mutation |
R4145 | T14406 | T14408 | nsubjpass | mutation,identified |
R4146 | T14407 | T14406 | compound | lil,mutation |
R4147 | T14409 | T14408 | auxpass | was,identified |
R4148 | T14410 | T14411 | mark | as,described |
R4149 | T14411 | T14408 | advcl | described,identified |
R4150 | T14412 | T14411 | prep | in,described |
R4151 | T14413 | T14412 | pobj | results,in |
R4152 | T14414 | T14408 | punct | .,identified |
R4153 | T14416 | T14417 | amod | Wild,type |
R4154 | T14417 | T14419 | nmod | type,mice |
R4155 | T14418 | T14417 | punct | -,type |
R4156 | T14419 | T14427 | nsubjpass | mice,obtained |
R4157 | T14420 | T14421 | nmod | FVB,N |
R4158 | T14421 | T14419 | nmod | N,mice |
R4159 | T14422 | T14421 | punct | /,N |
R4160 | T14423 | T14421 | cc | and,N |
R4161 | T14424 | T14425 | compound | C57BL,6J |
R4162 | T14425 | T14421 | conj | 6J,N |
R4163 | T14426 | T14425 | punct | /,6J |
R4164 | T14428 | T14419 | acl | used,mice |
R4165 | T14429 | T14428 | prep | for,used |
R4166 | T14430 | T14431 | amod | genetic,crosses |
R4167 | T14431 | T14429 | pobj | crosses,for |
R4168 | T14432 | T14427 | auxpass | were,obtained |
R4169 | T14433 | T14427 | prep | from,obtained |
R4170 | T14434 | T14435 | det | the,Laboratory |
R4171 | T14435 | T14433 | pobj | Laboratory,from |
R4172 | T14436 | T14435 | compound | Jackson,Laboratory |
R4173 | T14437 | T14438 | punct | (,Harbor |
R4174 | T14438 | T14435 | parataxis | Harbor,Laboratory |
R4175 | T14439 | T14438 | compound | Bar,Harbor |
R4176 | T14440 | T14438 | punct | ", ",Harbor |
R4177 | T14441 | T14438 | npadvmod | Maine,Harbor |
R4178 | T14442 | T14438 | punct | ", ",Harbor |
R4179 | T14443 | T14444 | compound | United,States |
R4180 | T14444 | T14438 | npadvmod | States,Harbor |
R4181 | T14445 | T14438 | punct | ),Harbor |
R4182 | T14446 | T14427 | punct | .,obtained |
R4183 | T14448 | T14449 | nsubj | Mice,were |
R4184 | T14450 | T14448 | acl | carrying,Mice |
R4185 | T14451 | T14452 | det | a,mutation |
R4186 | T14452 | T14450 | dobj | mutation,carrying |
R4187 | T14453 | T14452 | amod | null,mutation |
R4188 | T14454 | T14452 | prep | of,mutation |
R4189 | T14455 | T14454 | pobj | Fog2,of |
R4190 | T14456 | T14452 | acl | generated,mutation |
R4191 | T14457 | T14456 | prep | by,generated |
R4192 | T14458 | T14459 | compound | gene,targeting |
R4193 | T14459 | T14457 | pobj | targeting,by |
R4194 | T14460 | T14461 | punct | [,16 |
R4195 | T14461 | T14456 | parataxis | 16,generated |
R4196 | T14462 | T14461 | punct | ],16 |
R4197 | T14463 | T14464 | det | the,gift |
R4198 | T14464 | T14449 | attr | gift,were |
R4199 | T14465 | T14464 | amod | generous,gift |
R4200 | T14466 | T14464 | prep | of,gift |
R4201 | T14467 | T14468 | compound | Dr.,Orkin |
R4202 | T14468 | T14466 | pobj | Orkin,of |
R4203 | T14469 | T14468 | compound | Stuart,Orkin |
R4204 | T14470 | T14449 | punct | .,were |
R4205 | T15313 | T15314 | amod | Developmental,analysis |
R4206 | T15315 | T15314 | prep | of,analysis |
R4207 | T15316 | T15315 | pobj | mice,of |
R4208 | T15317 | T15314 | punct | .,analysis |
R4209 | T15319 | T15320 | amod | Timed,pregnancies |
R4210 | T15320 | T15321 | nsubjpass | pregnancies,set |
R4211 | T15322 | T15321 | auxpass | were,set |
R4212 | T15323 | T15321 | prt | up,set |
R4213 | T15324 | T15321 | prep | for,set |
R4214 | T15325 | T15324 | pobj | collection,for |
R4215 | T15326 | T15325 | prep | of,collection |
R4216 | T15327 | T15328 | nmod | E11.5,embryos |
R4217 | T15328 | T15326 | pobj | embryos,of |
R4218 | T15329 | T15330 | punct | –,E17.5 |
R4219 | T15330 | T15327 | prep | E17.5,E11.5 |
R4220 | T15331 | T15321 | punct | .,set |
R4221 | T15333 | T15334 | nsubj | Embryos,fixed |
R4222 | T15335 | T15334 | aux | were,fixed |
R4223 | T15336 | T15334 | punct | ", ",fixed |
R4224 | T15337 | T15334 | conj | dehydrated,fixed |
R4225 | T15338 | T15337 | punct | ", ",dehydrated |
R4226 | T15339 | T15337 | cc | and,dehydrated |
R4227 | T15340 | T15337 | conj | embedded,dehydrated |
R4228 | T15341 | T15340 | prep | in,embedded |
R4229 | T15342 | T15341 | pobj | paraffin,in |
R4230 | T15343 | T15344 | amod | prior,to |
R4231 | T15344 | T15334 | prep | to,fixed |
R4232 | T15345 | T15344 | pobj | sectioning,to |
R4233 | T15346 | T15334 | punct | .,fixed |
R4234 | T15348 | T15349 | prep | In,performed |
R4235 | T15350 | T15351 | amod | older,embryos |
R4236 | T15351 | T15348 | pobj | embryos,In |
R4237 | T15352 | T15349 | punct | ", ",performed |
R4238 | T15353 | T15354 | det | a,sternotomy |
R4239 | T15354 | T15349 | nsubjpass | sternotomy,performed |
R4240 | T15355 | T15354 | amod | median,sternotomy |
R4241 | T15356 | T15349 | auxpass | was,performed |
R4242 | T15357 | T15349 | prep | under,performed |
R4243 | T15358 | T15359 | amod | microscopic,guidance |
R4244 | T15359 | T15357 | pobj | guidance,under |
R4245 | T15360 | T15349 | punct | ", ",performed |
R4246 | T15361 | T15349 | cc | and,performed |
R4247 | T15362 | T15363 | nsubjpass | diaphragm,examined |
R4248 | T15363 | T15349 | conj | examined,performed |
R4249 | T15364 | T15362 | punct | ", ",diaphragm |
R4250 | T15365 | T15362 | conj | lungs,diaphragm |
R4251 | T15366 | T15365 | punct | ", ",lungs |
R4252 | T15367 | T15365 | cc | and,lungs |
R4253 | T15368 | T15365 | conj | heart,lungs |
R4254 | T15369 | T15363 | auxpass | were,examined |
R4255 | T15370 | T15349 | punct | .,performed |
R4256 | T15372 | T15373 | det | The,lungs |
R4257 | T15373 | T15374 | nsubjpass | lungs,removed |
R4258 | T15375 | T15373 | cc | and,lungs |
R4259 | T15376 | T15377 | amod | tracheobronchial,tree |
R4260 | T15377 | T15373 | conj | tree,lungs |
R4261 | T15378 | T15374 | auxpass | were,removed |
R4262 | T15379 | T15374 | cc | and,removed |
R4263 | T15380 | T15374 | conj | weighed,removed |
R4264 | T15381 | T15374 | punct | .,removed |
R4265 | T15383 | T15384 | amod | Whole,diaphragms |
R4266 | T15384 | T15385 | nsubjpass | diaphragms,isolated |
R4267 | T15386 | T15385 | auxpass | were,isolated |
R4268 | T15387 | T15385 | prep | from,isolated |
R4269 | T15388 | T15389 | amod | fixed,tissue |
R4270 | T15389 | T15387 | pobj | tissue,from |
R4271 | T15390 | T15389 | amod | thoracic,tissue |
R4272 | T15391 | T15389 | prep | from,tissue |
R4273 | T15392 | T15393 | nmod | E15.5,embryos |
R4274 | T15393 | T15391 | pobj | embryos,from |
R4275 | T15394 | T15392 | cc | and,E15.5 |
R4276 | T15395 | T15392 | conj | E17.5,E15.5 |
R4277 | T15396 | T15385 | punct | .,isolated |
R4278 | T15398 | T15399 | prep | For,dissected |
R4279 | T15400 | T15401 | compound | lung,culture |
R4280 | T15401 | T15398 | pobj | culture,For |
R4281 | T15402 | T15401 | compound | explant,culture |
R4282 | T15403 | T15399 | punct | ", ",dissected |
R4283 | T15404 | T15399 | nsubjpass | lungs,dissected |
R4284 | T15405 | T15399 | auxpass | were,dissected |
R4285 | T15406 | T15399 | prep | from,dissected |
R4286 | T15407 | T15408 | amod | fresh,embryos |
R4287 | T15408 | T15406 | pobj | embryos,from |
R4288 | T15409 | T15399 | prep | at,dissected |
R4289 | T15410 | T15409 | pobj | E11.5,at |
R4290 | T15411 | T15410 | cc | and,E11.5 |
R4291 | T15412 | T15410 | conj | E12.5,E11.5 |
R4292 | T15413 | T15399 | cc | and,dissected |
R4293 | T15414 | T15399 | conj | placed,dissected |
R4294 | T15415 | T15414 | prep | on,placed |
R4295 | T15416 | T15417 | amod | porous,membranes |
R4296 | T15417 | T15415 | pobj | membranes,on |
R4297 | T15418 | T15419 | nummod | 24,mm |
R4298 | T15419 | T15417 | nmod | mm,membranes |
R4299 | T15420 | T15419 | punct | -,mm |
R4300 | T15421 | T15422 | punct | (,μ |
R4301 | T15422 | T15417 | parataxis | μ,membranes |
R4302 | T15423 | T15422 | nummod | 0.4,μ |
R4303 | T15424 | T15422 | punct | -,μ |
R4304 | T15425 | T15422 | punct | ),μ |
R4305 | T15426 | T15417 | compound | polyester,membranes |
R4306 | T15427 | T15417 | acl | floated,membranes |
R4307 | T15428 | T15427 | prep | in,floated |
R4308 | T15429 | T15428 | pobj | wells,in |
R4309 | T15430 | T15429 | acl | containing,wells |
R4310 | T15431 | T15432 | nummod | 2,ml |
R4311 | T15432 | T15430 | dobj | ml,containing |
R4312 | T15433 | T15432 | prep | of,ml |
R4313 | T15434 | T15435 | poss | Dulbecco,medium |
R4314 | T15435 | T15433 | pobj | medium,of |
R4315 | T15436 | T15434 | case | 's,Dulbecco |
R4316 | T15437 | T15435 | amod | modified,medium |
R4317 | T15438 | T15435 | poss | Eagle,medium |
R4318 | T15439 | T15438 | case | 's,Eagle |
R4319 | T15440 | T15435 | punct | ", ",medium |
R4320 | T15441 | T15442 | compound | nutrient,mixture |
R4321 | T15442 | T15443 | compound | mixture,F |
R4322 | T15443 | T15435 | appos | F,medium |
R4323 | T15444 | T15443 | punct | -,F |
R4324 | T15445 | T15443 | nummod | 12,F |
R4325 | T15446 | T15447 | punct | (,Gibco |
R4326 | T15447 | T15443 | parataxis | Gibco,F |
R4327 | T15448 | T15449 | nummod | 11039,021 |
R4328 | T15449 | T15447 | dep | 021,Gibco |
R4329 | T15450 | T15449 | punct | –,021 |
R4330 | T15451 | T15447 | punct | ", ",Gibco |
R4331 | T15452 | T15447 | punct | ", ",Gibco |
R4332 | T15453 | T15454 | compound | San,Diego |
R4333 | T15454 | T15447 | npadvmod | Diego,Gibco |
R4334 | T15455 | T15447 | punct | ", ",Gibco |
R4335 | T15456 | T15447 | npadvmod | California,Gibco |
R4336 | T15457 | T15447 | punct | ", ",Gibco |
R4337 | T15458 | T15459 | compound | United,States |
R4338 | T15459 | T15447 | npadvmod | States,Gibco |
R4339 | T15460 | T15447 | punct | ),Gibco |
R4340 | T15461 | T15435 | punct | ", ",medium |
R4341 | T15462 | T15435 | acl | supplemented,medium |
R4342 | T15463 | T15462 | prep | with,supplemented |
R4343 | T15464 | T15465 | nummod | 10,% |
R4344 | T15465 | T15466 | nmod | %,serum |
R4345 | T15466 | T15463 | pobj | serum,with |
R4346 | T15467 | T15466 | amod | fetal,serum |
R4347 | T15468 | T15466 | amod | bovine,serum |
R4348 | T15469 | T15466 | punct | ", ",serum |
R4349 | T15470 | T15471 | nummod | 0.3,mg |
R4350 | T15471 | T15472 | nmod | mg,glutamine |
R4351 | T15472 | T15466 | conj | glutamine,serum |
R4352 | T15473 | T15474 | punct | /,ml |
R4353 | T15474 | T15471 | prep | ml,mg |
R4354 | T15475 | T15472 | compound | L,glutamine |
R4355 | T15476 | T15472 | punct | -,glutamine |
R4356 | T15477 | T15472 | punct | ", ",glutamine |
R4357 | T15478 | T15479 | nummod | 100,units |
R4358 | T15479 | T15480 | nmod | units,penicillin |
R4359 | T15480 | T15472 | conj | penicillin,glutamine |
R4360 | T15481 | T15482 | punct | /,ml |
R4361 | T15482 | T15479 | prep | ml,units |
R4362 | T15483 | T15480 | punct | ", ",penicillin |
R4363 | T15484 | T15485 | nummod | 100,mcg |
R4364 | T15485 | T15486 | nmod | mcg,streptomycin |
R4365 | T15486 | T15480 | conj | streptomycin,penicillin |
R4366 | T15487 | T15488 | punct | /,ml |
R4367 | T15488 | T15485 | prep | ml,mcg |
R4368 | T15489 | T15486 | punct | ", ",streptomycin |
R4369 | T15490 | T15486 | cc | and,streptomycin |
R4370 | T15491 | T15492 | nummod | 0.25,mcg |
R4371 | T15492 | T15493 | nmod | mcg,B |
R4372 | T15493 | T15486 | conj | B,streptomycin |
R4373 | T15494 | T15495 | punct | /,ml |
R4374 | T15495 | T15492 | prep | ml,mcg |
R4375 | T15496 | T15493 | compound | amphotericin,B |
R4376 | T15497 | T15399 | punct | .,dissected |
R4377 | T15499 | T15500 | compound | Lung,explants |
R4378 | T15500 | T15501 | nsubjpass | explants,cultured |
R4379 | T15502 | T15501 | auxpass | were,cultured |
R4380 | T15503 | T15501 | prep | at,cultured |
R4381 | T15504 | T15505 | nummod | 37,°C |
R4382 | T15505 | T15503 | pobj | °C,at |
R4383 | T15506 | T15501 | prep | in,cultured |
R4384 | T15507 | T15508 | nummod | 95,% |
R4385 | T15508 | T15509 | compound | %,air |
R4386 | T15509 | T15506 | pobj | air,in |
R4387 | T15510 | T15509 | punct | /,air |
R4388 | T15511 | T15512 | nummod | 5,% |
R4389 | T15512 | T15513 | compound | %,CO2 |
R4390 | T15513 | T15509 | appos | CO2,air |
R4391 | T15514 | T15501 | prep | for,cultured |
R4392 | T15515 | T15516 | advmod | up,5 |
R4393 | T15516 | T15518 | nummod | 5,d |
R4394 | T15517 | T15516 | quantmod | to,5 |
R4395 | T15518 | T15514 | pobj | d,for |
R4396 | T15519 | T15501 | punct | .,cultured |
R4397 | T15521 | T15522 | nsubjpass | They,photographed |
R4398 | T15523 | T15522 | auxpass | were,photographed |
R4399 | T15524 | T15522 | advmod | daily,photographed |
R4400 | T15525 | T15522 | prep | with,photographed |
R4401 | T15526 | T15527 | det | a,microscope |
R4402 | T15527 | T15525 | pobj | microscope,with |
R4403 | T15528 | T15527 | amod | dissecting,microscope |
R4404 | T15529 | T15530 | punct | (,MZ12.5 |
R4405 | T15530 | T15527 | parataxis | MZ12.5,microscope |
R4406 | T15531 | T15530 | punct | ", ",MZ12.5 |
R4407 | T15532 | T15530 | npadvmod | Leica,MZ12.5 |
R4408 | T15533 | T15530 | punct | ", ",MZ12.5 |
R4409 | T15534 | T15530 | npadvmod | Wetzlar,MZ12.5 |
R4410 | T15535 | T15530 | punct | ", ",MZ12.5 |
R4411 | T15536 | T15530 | npadvmod | Germany,MZ12.5 |
R4412 | T15537 | T15530 | punct | ),MZ12.5 |
R4413 | T15538 | T15527 | acl | equipped,microscope |
R4414 | T15539 | T15538 | prep | with,equipped |
R4415 | T15540 | T15541 | det | a,camera |
R4416 | T15541 | T15539 | pobj | camera,with |
R4417 | T15542 | T15543 | nmod | Leica,DC500 |
R4418 | T15543 | T15541 | nmod | DC500,camera |
R4419 | T15544 | T15541 | amod | digital,camera |
R4420 | T15545 | T15522 | punct | .,photographed |
R4421 | T15547 | T15548 | amod | Transgenic,mice |
R4422 | T15548 | T15549 | nsubjpass | mice,developed |
R4423 | T15550 | T15548 | acl | carrying,mice |
R4424 | T15551 | T15552 | det | the,gene |
R4425 | T15552 | T15550 | dobj | gene,carrying |
R4426 | T15553 | T15552 | compound | lacZ,gene |
R4427 | T15554 | T15552 | acl | driven,gene |
R4428 | T15555 | T15554 | agent | by,driven |
R4429 | T15556 | T15557 | det | the,promoter |
R4430 | T15557 | T15555 | pobj | promoter,by |
R4431 | T15558 | T15557 | compound | Fog2,promoter |
R4432 | T15559 | T15549 | aux | have,developed |
R4433 | T15560 | T15549 | auxpass | been,developed |
R4434 | T15561 | T15549 | agent | by,developed |
R4435 | T15562 | T15563 | compound | S.,Tevosian |
R4436 | T15563 | T15561 | pobj | Tevosian,by |
R4437 | T15564 | T15549 | punct | .,developed |
R4438 | T15566 | T15567 | prep | In,incorporated |
R4439 | T15568 | T15569 | det | these,animals |
R4440 | T15569 | T15566 | pobj | animals,In |
R4441 | T15570 | T15567 | punct | ", ",incorporated |
R4442 | T15571 | T15572 | det | the,gene |
R4443 | T15572 | T15567 | nsubjpass | gene,incorporated |
R4444 | T15573 | T15572 | compound | lacZ,gene |
R4445 | T15574 | T15567 | auxpass | is,incorporated |
R4446 | T15575 | T15576 | punct | (,knocked |
R4447 | T15576 | T15567 | parataxis | knocked,incorporated |
R4448 | T15577 | T15576 | punct | “,knocked |
R4449 | T15578 | T15576 | punct | -,knocked |
R4450 | T15579 | T15576 | prt | in,knocked |
R4451 | T15580 | T15576 | punct | ”,knocked |
R4452 | T15581 | T15576 | punct | ),knocked |
R4453 | T15582 | T15567 | prep | into,incorporated |
R4454 | T15583 | T15584 | det | the,locus |
R4455 | T15584 | T15582 | pobj | locus,into |
R4456 | T15585 | T15584 | compound | Fog2,locus |
R4457 | T15586 | T15587 | aux | to,allow |
R4458 | T15587 | T15567 | advcl | allow,incorporated |
R4459 | T15588 | T15589 | compound | β,galactosidase |
R4460 | T15589 | T15591 | compound | galactosidase,expression |
R4461 | T15590 | T15589 | punct | -,galactosidase |
R4462 | T15591 | T15587 | dobj | expression,allow |
R4463 | T15592 | T15587 | prep | as,allow |
R4464 | T15593 | T15594 | det | a,protein |
R4465 | T15594 | T15592 | pobj | protein,as |
R4466 | T15595 | T15594 | compound | fusion,protein |
R4467 | T15596 | T15594 | prep | in,protein |
R4468 | T15597 | T15596 | pobj | frame,in |
R4469 | T15598 | T15597 | prep | with,frame |
R4470 | T15599 | T15600 | det | the,acids |
R4471 | T15600 | T15598 | pobj | acids,with |
R4472 | T15601 | T15600 | amod | first,acids |
R4473 | T15602 | T15600 | nummod | 235,acids |
R4474 | T15603 | T15600 | compound | amino,acids |
R4475 | T15604 | T15600 | prep | of,acids |
R4476 | T15605 | T15606 | det | the,protein |
R4477 | T15606 | T15604 | pobj | protein,of |
R4478 | T15607 | T15606 | compound | FOG2,protein |
R4479 | T15608 | T15567 | punct | .,incorporated |
R4480 | T15610 | T15611 | det | The,module |
R4481 | T15611 | T15615 | nsubjpass | module,followed |
R4482 | T15612 | T15613 | compound | Fog2,lacZ |
R4483 | T15613 | T15611 | compound | lacZ,module |
R4484 | T15614 | T15613 | punct | -,lacZ |
R4485 | T15616 | T15615 | auxpass | is,followed |
R4486 | T15617 | T15615 | agent | by,followed |
R4487 | T15618 | T15619 | det | an,cassette |
R4488 | T15619 | T15617 | pobj | cassette,by |
R4489 | T15620 | T15621 | compound | ires,eGFP |
R4490 | T15621 | T15619 | compound | eGFP,cassette |
R4491 | T15622 | T15621 | punct | -,eGFP |
R4492 | T15623 | T15615 | punct | .,followed |
R4493 | T15625 | T15626 | nsubj | This,creates |
R4494 | T15627 | T15628 | det | a,allele |
R4495 | T15628 | T15626 | dobj | allele,creates |
R4496 | T15629 | T15628 | amod | null,allele |
R4497 | T15630 | T15628 | prep | of,allele |
R4498 | T15631 | T15632 | compound | Fog2,gene |
R4499 | T15632 | T15630 | pobj | gene,of |
R4500 | T15633 | T15626 | punct | .,creates |
R4501 | T15635 | T15636 | det | The,construct |
R4502 | T15636 | T15642 | nsubjpass | construct,linearized |
R4503 | T15637 | T15638 | compound | Fog2,eGFP |
R4504 | T15638 | T15636 | compound | eGFP,construct |
R4505 | T15639 | T15638 | punct | -,eGFP |
R4506 | T15640 | T15638 | compound | LacZ,eGFP |
R4507 | T15641 | T15638 | punct | -,eGFP |
R4508 | T15643 | T15642 | auxpass | was,linearized |
R4509 | T15644 | T15642 | prep | with,linearized |
R4510 | T15645 | T15644 | pobj | KspI,with |
R4511 | T15646 | T15642 | cc | and,linearized |
R4512 | T15647 | T15642 | conj | electroporated,linearized |
R4513 | T15648 | T15647 | prep | into,electroporated |
R4514 | T15649 | T15650 | det | the,cells |
R4515 | T15650 | T15648 | pobj | cells,into |
R4516 | T15651 | T15650 | compound | CJ7,cells |
R4517 | T15652 | T15650 | compound | ES,cells |
R4518 | T15653 | T15642 | punct | .,linearized |
R4519 | T15655 | T15656 | det | The,clone |
R4520 | T15656 | T15659 | nsubjpass | clone,selected |
R4521 | T15657 | T15658 | advmod | correctly,targeted |
R4522 | T15658 | T15656 | amod | targeted,clone |
R4523 | T15660 | T15659 | auxpass | was,selected |
R4524 | T15661 | T15659 | prep | by,selected |
R4525 | T15662 | T15663 | det | the,analysis |
R4526 | T15663 | T15661 | pobj | analysis,by |
R4527 | T15664 | T15665 | compound | Southern,blot |
R4528 | T15665 | T15663 | compound | blot,analysis |
R4529 | T15666 | T15659 | cc | and,selected |
R4530 | T15667 | T15659 | conj | injected,selected |
R4531 | T15668 | T15667 | prep | into,injected |
R4532 | T15669 | T15670 | compound | C57BL,6J |
R4533 | T15670 | T15672 | compound | 6J,blastocysts |
R4534 | T15671 | T15670 | punct | /,6J |
R4535 | T15672 | T15668 | pobj | blastocysts,into |
R4536 | T15673 | T15659 | punct | .,selected |
R4537 | T15675 | T15676 | compound | Fog2,eGFP |
R4538 | T15676 | T15680 | compound | eGFP,animals |
R4539 | T15677 | T15676 | punct | -,eGFP |
R4540 | T15678 | T15676 | compound | lacZ,eGFP |
R4541 | T15679 | T15676 | punct | -,eGFP |
R4542 | T15680 | T15681 | nsubjpass | animals,maintained |
R4543 | T15682 | T15681 | auxpass | were,maintained |
R4544 | T15683 | T15681 | prep | on,maintained |
R4545 | T15684 | T15685 | det | the,background |
R4546 | T15685 | T15683 | pobj | background,on |
R4547 | T15686 | T15685 | amod | mixed,background |
R4548 | T15687 | T15688 | nmod | C57BL,6J |
R4549 | T15688 | T15685 | nmod | 6J,background |
R4550 | T15689 | T15688 | punct | /,6J |
R4551 | T15690 | T15688 | punct | /,6J |
R4552 | T15691 | T15688 | nummod | 129,6J |
R4553 | T15692 | T15681 | punct | .,maintained |
R4554 | T15694 | T15695 | compound | lacZ,Expression |
R4555 | T15695 | T15696 | nsubjpass | Expression,analyzed |
R4556 | T15697 | T15695 | prep | in,Expression |
R4557 | T15698 | T15699 | amod | whole,lungs |
R4558 | T15699 | T15697 | pobj | lungs,in |
R4559 | T15700 | T15699 | amod | dissected,lungs |
R4560 | T15701 | T15699 | amod | embryonic,lungs |
R4561 | T15702 | T15696 | auxpass | was,analyzed |
R4562 | T15703 | T15696 | prep | by,analyzed |
R4563 | T15704 | T15703 | pcomp | staining,by |
R4564 | T15705 | T15704 | prep | for,staining |
R4565 | T15706 | T15707 | compound | β,galactosidase |
R4566 | T15707 | T15709 | compound | galactosidase,activity |
R4567 | T15708 | T15707 | punct | -,galactosidase |
R4568 | T15709 | T15705 | pobj | activity,for |
R4569 | T15710 | T15704 | prep | with,staining |
R4570 | T15711 | T15712 | compound | X,gal |
R4571 | T15712 | T15710 | pobj | gal,with |
R4572 | T15713 | T15712 | punct | -,gal |
R4573 | T15714 | T15704 | prep | after,staining |
R4574 | T15715 | T15714 | pobj | fixation,after |
R4575 | T15716 | T15715 | prep | for,fixation |
R4576 | T15717 | T15718 | nummod | 30,min |
R4577 | T15718 | T15716 | pobj | min,for |
R4578 | T15719 | T15696 | punct | .,analyzed |
R4581 | T16000 | T16001 | compound | RT,PCR |
R4582 | T16002 | T16001 | punct | -,PCR |
R4583 | T16003 | T16001 | cc | and,PCR |
R4584 | T16004 | T16005 | compound | sequence,analysis |
R4585 | T16005 | T16001 | conj | analysis,PCR |
R4586 | T16006 | T16001 | prep | in,PCR |
R4587 | T16007 | T16008 | det | the,mouse |
R4588 | T16008 | T16006 | pobj | mouse,in |
R4589 | T16009 | T16001 | punct | .,PCR |
R4590 | T16011 | T16012 | nsubjpass | RNA,extracted |
R4591 | T16013 | T16012 | auxpass | was,extracted |
R4592 | T16014 | T16012 | prep | by,extracted |
R4593 | T16015 | T16016 | amod | standard,techniques |
R4594 | T16016 | T16014 | pobj | techniques,by |
R4595 | T16017 | T16012 | prep | from,extracted |
R4596 | T16018 | T16019 | amod | thoracic,tissue |
R4597 | T16019 | T16017 | pobj | tissue,from |
R4598 | T16020 | T16019 | amod | embryonic,tissue |
R4599 | T16021 | T16012 | punct | .,extracted |
R4600 | T16023 | T16024 | compound | RT,PCR |
R4601 | T16024 | T16026 | nsubjpass | PCR,performed |
R4602 | T16025 | T16024 | punct | -,PCR |
R4603 | T16027 | T16026 | auxpass | was,performed |
R4604 | T16028 | T16026 | advcl | using,performed |
R4605 | T16029 | T16030 | nummod | six,sets |
R4606 | T16030 | T16028 | dobj | sets,using |
R4607 | T16031 | T16030 | compound | primer,sets |
R4608 | T16032 | T16030 | acl | designed,sets |
R4609 | T16033 | T16034 | aux | to,cover |
R4610 | T16034 | T16032 | advcl | cover,designed |
R4611 | T16035 | T16036 | det | the,gene |
R4612 | T16036 | T16034 | dobj | gene,cover |
R4613 | T16037 | T16036 | compound | Fog2,gene |
R4614 | T16038 | T16026 | punct | .,performed |
R4615 | T16040 | T16041 | compound | RT,PCR |
R4616 | T16041 | T16043 | nsubjpass | PCR,repeated |
R4617 | T16042 | T16041 | punct | -,PCR |
R4618 | T16044 | T16043 | auxpass | was,repeated |
R4619 | T16045 | T16043 | prep | with,repeated |
R4620 | T16046 | T16047 | amod | radiolabeled,primers |
R4621 | T16047 | T16045 | pobj | primers,with |
R4622 | T16048 | T16049 | aux | to,amplify |
R4623 | T16049 | T16043 | advcl | amplify,repeated |
R4624 | T16050 | T16051 | det | an,region |
R4625 | T16051 | T16049 | dobj | region,amplify |
R4626 | T16052 | T16053 | advmod | abnormally,spliced |
R4627 | T16053 | T16051 | amod | spliced,region |
R4628 | T16054 | T16051 | prep | of,region |
R4629 | T16055 | T16056 | det | the,gene |
R4630 | T16056 | T16054 | pobj | gene,of |
R4631 | T16057 | T16058 | punct | (,S1 |
R4632 | T16058 | T16043 | parataxis | S1,repeated |
R4633 | T16059 | T16058 | compound | Table,S1 |
R4634 | T16060 | T16058 | punct | ),S1 |
R4635 | T16061 | T16043 | punct | ", ",repeated |
R4636 | T16062 | T16043 | cc | and,repeated |
R4637 | T16063 | T16064 | det | the,product |
R4638 | T16064 | T16065 | nsubjpass | product,run |
R4639 | T16065 | T16043 | conj | run,repeated |
R4640 | T16066 | T16065 | auxpass | was,run |
R4641 | T16067 | T16065 | prep | on,run |
R4642 | T16068 | T16069 | det | a,gel |
R4643 | T16069 | T16067 | pobj | gel,on |
R4644 | T16070 | T16069 | amod | denaturing,gel |
R4645 | T16071 | T16069 | compound | sequencing,gel |
R4646 | T16072 | T16065 | prep | according,run |
R4647 | T16073 | T16072 | prep | to,according |
R4648 | T16074 | T16075 | amod | standard,techniques |
R4649 | T16075 | T16073 | pobj | techniques,to |
R4650 | T16076 | T16065 | punct | .,run |
R4651 | T16078 | T16079 | det | The,product |
R4652 | T16079 | T16083 | nsubjpass | product,cloned |
R4653 | T16080 | T16081 | compound | RT,PCR |
R4654 | T16081 | T16079 | compound | PCR,product |
R4655 | T16082 | T16081 | punct | -,PCR |
R4656 | T16084 | T16083 | auxpass | was,cloned |
R4657 | T16085 | T16083 | prep | into,cloned |
R4658 | T16086 | T16087 | compound | pCR2.1,vector |
R4659 | T16087 | T16085 | pobj | vector,into |
R4660 | T16088 | T16083 | advcl | using,cloned |
R4661 | T16089 | T16090 | compound | TOPO,Kit |
R4662 | T16090 | T16088 | dobj | Kit,using |
R4663 | T16091 | T16090 | compound | TA,Kit |
R4664 | T16092 | T16090 | compound | Cloning,Kit |
R4665 | T16093 | T16094 | punct | (,Invitrogen |
R4666 | T16094 | T16090 | parataxis | Invitrogen,Kit |
R4667 | T16095 | T16094 | punct | ", ",Invitrogen |
R4668 | T16096 | T16094 | npadvmod | Carlsbad,Invitrogen |
R4669 | T16097 | T16094 | punct | ", ",Invitrogen |
R4670 | T16098 | T16094 | npadvmod | California,Invitrogen |
R4671 | T16099 | T16094 | punct | ", ",Invitrogen |
R4672 | T16100 | T16101 | compound | United,States |
R4673 | T16101 | T16094 | npadvmod | States,Invitrogen |
R4674 | T16102 | T16094 | punct | ),Invitrogen |
R4675 | T16103 | T16083 | cc | and,cloned |
R4676 | T16104 | T16083 | conj | sequenced,cloned |
R4677 | T16105 | T16104 | advcl | using,sequenced |
R4678 | T16106 | T16107 | npadvmod | gene,specific |
R4679 | T16107 | T16109 | amod | specific,primers |
R4680 | T16108 | T16107 | punct | -,specific |
R4681 | T16109 | T16105 | dobj | primers,using |
R4682 | T16110 | T16083 | punct | .,cloned |
R4683 | T16112 | T16113 | compound | Sequence,analysis |
R4684 | T16113 | T16114 | nsubjpass | analysis,done |
R4685 | T16115 | T16114 | auxpass | was,done |
R4686 | T16116 | T16114 | advcl | using,done |
R4687 | T16117 | T16116 | dobj | Sequencher,using |
R4688 | T16118 | T16117 | nummod | 4.1,Sequencher |
R4689 | T16119 | T16120 | punct | (,Codes |
R4690 | T16120 | T16117 | parataxis | Codes,Sequencher |
R4691 | T16121 | T16120 | compound | Gene,Codes |
R4692 | T16122 | T16120 | punct | ", ",Codes |
R4693 | T16123 | T16124 | compound | Ann,Arbor |
R4694 | T16124 | T16120 | npadvmod | Arbor,Codes |
R4695 | T16125 | T16120 | punct | ", ",Codes |
R4696 | T16126 | T16120 | npadvmod | Michigan,Codes |
R4697 | T16127 | T16120 | punct | ", ",Codes |
R4698 | T16128 | T16129 | compound | United,States |
R4699 | T16129 | T16120 | npadvmod | States,Codes |
R4700 | T16130 | T16120 | punct | ),Codes |
R4701 | T16131 | T16114 | punct | .,done |
R4702 | T16289 | T16290 | advmod | In,situ |
R4703 | T16290 | T16291 | amod | situ,hybridization |
R4704 | T16292 | T16291 | punct | .,hybridization |
R4705 | T16294 | T16295 | prep | After,subjected |
R4706 | T16296 | T16294 | pobj | dehydration,After |
R4707 | T16297 | T16296 | cc | and,dehydration |
R4708 | T16298 | T16296 | conj | embedding,dehydration |
R4709 | T16299 | T16298 | prep | in,embedding |
R4710 | T16300 | T16301 | compound | paraffin,wax |
R4711 | T16301 | T16299 | pobj | wax,in |
R4712 | T16302 | T16295 | punct | ", ",subjected |
R4713 | T16303 | T16304 | nummod | 10,μ |
R4714 | T16304 | T16306 | compound | μ,sections |
R4715 | T16305 | T16304 | punct | -,μ |
R4716 | T16306 | T16295 | nsubjpass | sections,subjected |
R4717 | T16307 | T16295 | auxpass | were,subjected |
R4718 | T16308 | T16295 | prep | to,subjected |
R4719 | T16309 | T16310 | amod | radioactive,hybridization |
R4720 | T16310 | T16308 | pobj | hybridization,to |
R4721 | T16311 | T16312 | advmod | in,situ |
R4722 | T16312 | T16310 | amod | situ,hybridization |
R4723 | T16313 | T16314 | mark | as,described |
R4724 | T16314 | T16295 | advcl | described,subjected |
R4725 | T16315 | T16316 | punct | [,53 |
R4726 | T16316 | T16295 | parataxis | 53,subjected |
R4727 | T16317 | T16316 | punct | ],53 |
R4728 | T16318 | T16295 | punct | .,subjected |
R4729 | T16320 | T16321 | nsubjpass | Probes,prepared |
R4730 | T16322 | T16320 | acl | labeled,Probes |
R4731 | T16323 | T16322 | prep | with,labeled |
R4732 | T16324 | T16323 | pobj | 35S,with |
R4733 | T16325 | T16321 | auxpass | were,prepared |
R4734 | T16326 | T16321 | prep | by,prepared |
R4735 | T16327 | T16328 | amod | run,transcription |
R4736 | T16328 | T16326 | pobj | transcription,by |
R4737 | T16329 | T16327 | punct | -,run |
R4738 | T16330 | T16327 | prt | off,run |
R4739 | T16331 | T16328 | prep | of,transcription |
R4740 | T16332 | T16333 | amod | linearized,templates |
R4741 | T16333 | T16331 | pobj | templates,of |
R4742 | T16334 | T16333 | compound | plasmid,templates |
R4743 | T16335 | T16321 | cc | and,prepared |
R4744 | T16336 | T16321 | conj | hybridized,prepared |
R4745 | T16337 | T16336 | prep | to,hybridized |
R4746 | T16338 | T16339 | compound | tissue,sections |
R4747 | T16339 | T16337 | pobj | sections,to |
R4748 | T16340 | T16321 | punct | .,prepared |
R4749 | T16342 | T16343 | nsubjpass | Nuclei,counterstained |
R4750 | T16344 | T16343 | auxpass | were,counterstained |
R4751 | T16345 | T16343 | prep | with,counterstained |
R4752 | T16346 | T16345 | pobj | Hoescht,with |
R4753 | T16347 | T16346 | nummod | 33258,Hoescht |
R4754 | T16348 | T16343 | punct | ", ",counterstained |
R4755 | T16349 | T16343 | cc | and,counterstained |
R4756 | T16350 | T16351 | nsubjpass | signal,imaged |
R4757 | T16351 | T16343 | conj | imaged,counterstained |
R4758 | T16352 | T16351 | auxpass | was,imaged |
R4759 | T16353 | T16351 | advcl | using,imaged |
R4760 | T16354 | T16355 | amod | fluorescent,microscopy |
R4761 | T16355 | T16353 | dobj | microscopy,using |
R4762 | T16356 | T16354 | cc | and,fluorescent |
R4763 | T16357 | T16354 | conj | darkfield,fluorescent |
R4764 | T16358 | T16351 | punct | .,imaged |
R4765 | T16688 | T16689 | amod | Human,extraction |
R4766 | T16690 | T16689 | compound | DNA,extraction |
R4767 | T16691 | T16689 | cc | and,extraction |
R4768 | T16692 | T16693 | compound | sequence,analysis |
R4769 | T16693 | T16689 | conj | analysis,extraction |
R4770 | T16694 | T16693 | punct | .,analysis |
R4771 | T16696 | T16697 | nsubjpass | DNA,isolated |
R4772 | T16698 | T16697 | auxpass | was,isolated |
R4773 | T16699 | T16697 | prep | from,isolated |
R4774 | T16700 | T16701 | compound | paraffin,blocks |
R4775 | T16701 | T16699 | pobj | blocks,from |
R4776 | T16702 | T16697 | prep | by,isolated |
R4777 | T16703 | T16704 | compound | phenol,chloroform |
R4778 | T16704 | T16706 | compound | chloroform,extraction |
R4779 | T16705 | T16704 | punct | -,chloroform |
R4780 | T16706 | T16702 | pobj | extraction,by |
R4781 | T16707 | T16708 | punct | [,55 |
R4782 | T16708 | T16697 | parataxis | 55,isolated |
R4783 | T16709 | T16708 | nummod | 54,55 |
R4784 | T16710 | T16708 | punct | ",",55 |
R4785 | T16711 | T16708 | punct | ],55 |
R4786 | T16712 | T16697 | punct | ", ",isolated |
R4787 | T16713 | T16697 | cc | and,isolated |
R4788 | T16714 | T16697 | conj | from,isolated |
R4789 | T16715 | T16716 | amod | frozen,tissues |
R4790 | T16716 | T16714 | pobj | tissues,from |
R4791 | T16717 | T16714 | prep | by,from |
R4792 | T16718 | T16719 | amod | standard,techniques |
R4793 | T16719 | T16717 | pobj | techniques,by |
R4794 | T16720 | T16697 | punct | .,isolated |
R4795 | T16722 | T16723 | nsubjpass | Primers,designed |
R4796 | T16724 | T16723 | auxpass | were,designed |
R4797 | T16725 | T16726 | aux | to,amplify |
R4798 | T16726 | T16723 | advcl | amplify,designed |
R4799 | T16727 | T16728 | compound | FOG2,exons |
R4800 | T16728 | T16726 | dobj | exons,amplify |
R4801 | T16729 | T16728 | compound | coding,exons |
R4802 | T16730 | T16728 | cc | plus,exons |
R4803 | T16731 | T16732 | nummod | 50,bp |
R4804 | T16732 | T16728 | conj | bp,exons |
R4805 | T16733 | T16732 | prep | of,bp |
R4806 | T16734 | T16735 | amod | flanking,sequence |
R4807 | T16735 | T16733 | pobj | sequence,of |
R4808 | T16736 | T16735 | amod | upstream,sequence |
R4809 | T16737 | T16736 | cc | and,upstream |
R4810 | T16738 | T16736 | conj | downstream,upstream |
R4811 | T16739 | T16723 | punct | .,designed |
R4812 | T16741 | T16742 | compound | PCR,amplification |
R4813 | T16742 | T16743 | nsubjpass | amplification,performed |
R4814 | T16744 | T16742 | cc | and,amplification |
R4815 | T16745 | T16742 | conj | sequencing,amplification |
R4816 | T16746 | T16743 | auxpass | were,performed |
R4817 | T16747 | T16743 | prep | by,performed |
R4818 | T16748 | T16749 | amod | standard,methods |
R4819 | T16749 | T16747 | pobj | methods,by |
R4820 | T16750 | T16743 | punct | .,performed |
R4821 | T16752 | T16753 | compound | Primer,sequences |
R4822 | T16753 | T16754 | nsubjpass | sequences,listed |
R4823 | T16755 | T16753 | acl | used,sequences |
R4824 | T16756 | T16754 | auxpass | are,listed |
R4825 | T16757 | T16754 | prep | in,listed |
R4826 | T16758 | T16759 | compound | Table,S2 |
R4827 | T16759 | T16757 | pobj | S2,in |
R4828 | T16760 | T16754 | punct | .,listed |
R4829 | T16762 | T16763 | compound | Sequence,analysis |
R4830 | T16763 | T16764 | nsubjpass | analysis,done |
R4831 | T16765 | T16764 | auxpass | was,done |
R4832 | T16766 | T16764 | prep | with,done |
R4833 | T16767 | T16766 | pobj | Sequencher,with |
R4834 | T16768 | T16767 | nummod | 4.1,Sequencher |
R4835 | T16769 | T16770 | punct | (,Codes |
R4836 | T16770 | T16767 | parataxis | Codes,Sequencher |
R4837 | T16771 | T16770 | compound | Gene,Codes |
R4838 | T16772 | T16770 | punct | ),Codes |
R4839 | T16773 | T16764 | punct | .,done |
R4840 | T16775 | T16776 | nsubjpass | DNA,extracted |
R4841 | T16777 | T16775 | prep | from,DNA |
R4842 | T16778 | T16779 | det | the,parents |
R4843 | T16779 | T16777 | pobj | parents,from |
R4844 | T16780 | T16779 | prep | of,parents |
R4845 | T16781 | T16782 | nummod | one,patient |
R4846 | T16782 | T16780 | pobj | patient,of |
R4847 | T16783 | T16782 | compound | autopsy,patient |
R4848 | T16784 | T16776 | auxpass | was,extracted |
R4849 | T16785 | T16776 | prep | from,extracted |
R4850 | T16786 | T16787 | amod | fresh,samples |
R4851 | T16787 | T16785 | pobj | samples,from |
R4852 | T16788 | T16787 | compound | blood,samples |
R4853 | T16789 | T16776 | punct | .,extracted |
R4854 | T16791 | T16792 | det | A,set |
R4855 | T16792 | T16794 | nsubjpass | set,sent |
R4856 | T16793 | T16792 | amod | second,set |
R4857 | T16795 | T16792 | prep | of,set |
R4858 | T16796 | T16797 | compound | blood,samples |
R4859 | T16797 | T16795 | pobj | samples,of |
R4860 | T16798 | T16794 | auxpass | was,sent |
R4861 | T16799 | T16794 | prep | to,sent |
R4862 | T16800 | T16801 | det | an,laboratory |
R4863 | T16801 | T16799 | pobj | laboratory,to |
R4864 | T16802 | T16801 | amod | outside,laboratory |
R4865 | T16803 | T16804 | npadvmod | CLIA,certified |
R4866 | T16804 | T16801 | amod | certified,laboratory |
R4867 | T16805 | T16804 | punct | -,certified |
R4868 | T16806 | T16794 | prep | for,sent |
R4869 | T16807 | T16808 | compound | DNA,extraction |
R4870 | T16808 | T16806 | pobj | extraction,for |
R4871 | T16809 | T16808 | punct | ", ",extraction |
R4872 | T16810 | T16808 | conj | PCR,extraction |
R4873 | T16811 | T16810 | punct | ", ",PCR |
R4874 | T16812 | T16810 | conj | sequencing,PCR |
R4875 | T16813 | T16812 | punct | ", ",sequencing |
R4876 | T16814 | T16812 | cc | and,sequencing |
R4877 | T16815 | T16812 | conj | analysis,sequencing |
R4878 | T16816 | T16794 | punct | .,sent |
R4879 | T16818 | T16819 | compound | Paternity,testing |
R4880 | T16819 | T16820 | nsubjpass | testing,performed |
R4881 | T16821 | T16820 | auxpass | was,performed |
R4882 | T16822 | T16820 | agent | by,performed |
R4883 | T16823 | T16824 | det | the,laboratory |
R4884 | T16824 | T16822 | pobj | laboratory,by |
R4885 | T16825 | T16824 | amod | outside,laboratory |
R4886 | T16826 | T16820 | advcl | using,performed |
R4887 | T16827 | T16828 | det | a,panel |
R4888 | T16828 | T16826 | dobj | panel,using |
R4889 | T16829 | T16828 | amod | standard,panel |
R4890 | T16830 | T16828 | prep | of,panel |
R4891 | T16831 | T16830 | pobj | markers,of |
R4892 | T16832 | T16820 | punct | .,performed |
R4893 | T16834 | T16835 | compound | SNP,genotyping |
R4894 | T16835 | T16836 | nsubjpass | genotyping,done |
R4895 | T16837 | T16836 | auxpass | was,done |
R4896 | T16838 | T16836 | advcl | using,done |
R4897 | T16839 | T16840 | nmod | Harvard,Center |
R4898 | T16840 | T16842 | nmod | Center,facility |
R4899 | T16841 | T16840 | nmod | Partners,Center |
R4900 | T16842 | T16838 | dobj | facility,using |
R4901 | T16843 | T16840 | prep | for,Center |
R4902 | T16844 | T16843 | pobj | Genetics,for |
R4903 | T16845 | T16844 | cc | and,Genetics |
R4904 | T16846 | T16844 | conj | Genomics,Genetics |
R4905 | T16847 | T16842 | compound | genotyping,facility |
R4906 | T16848 | T16842 | compound | core,facility |
R4907 | T16849 | T16850 | punct | (,Cambridge |
R4908 | T16850 | T16842 | parataxis | Cambridge,facility |
R4909 | T16851 | T16850 | punct | ", ",Cambridge |
R4910 | T16852 | T16850 | npadvmod | Massachusetts,Cambridge |
R4911 | T16853 | T16850 | punct | ", ",Cambridge |
R4912 | T16854 | T16855 | compound | United,States |
R4913 | T16855 | T16850 | npadvmod | States,Cambridge |
R4914 | T16856 | T16850 | punct | ),Cambridge |
R4915 | T16857 | T16836 | punct | .,done |
R45 | T1050 | T1049 | prep | of,analysis |
R42 | T1046 | T1047 | prep | In,identified |
R43 | T1048 | T1049 | det | an,analysis |
R44 | T1049 | T1046 | pobj | analysis,In |
R15 | T1016 | T1018 | nsubj | hernia,are |
R22 | T1025 | T1018 | acomp | associated,are |
R23 | T1026 | T1025 | prep | with,associated |
R24 | T1027 | T1028 | amod | significant,mortality |
R25 | T1028 | T1026 | pobj | mortality,with |
R26 | T1029 | T1028 | cc | and,mortality |
R27 | T1030 | T1028 | conj | morbidity,mortality |
R28 | T1031 | T1018 | prep | in,are |
R29 | T1032 | T1031 | pobj | neonates,in |
R30 | T1033 | T1024 | punct | ;,is |
R31 | T1034 | T1024 | advmod | however,is |
R32 | T1035 | T1024 | punct | ", ",is |
R33 | T1036 | T1037 | det | the,basis |
R36 | T1039 | T1037 | prep | of,basis |
R37 | T1040 | T1041 | det | these,anomalies |
R40 | T1043 | T1024 | acomp | unknown,is |
R41 | T1044 | T1024 | punct | .,is |
R46 | T1051 | T1052 | compound | E18.5,embryos |
R47 | T1052 | T1050 | pobj | embryos,of |
R48 | T1053 | T1052 | acl | derived,embryos |
R49 | T1054 | T1053 | prep | from,derived |
R50 | T1055 | T1054 | pobj | mice,from |
R51 | T1056 | T1055 | acl | treated,mice |
R52 | T1057 | T1056 | prep | with,treated |
R53 | T1058 | T1059 | compound | N,ethyl |
R56 | T1061 | T1059 | punct | -,ethyl |
R57 | T1062 | T1063 | compound | N,nitrosourea |
R60 | T1065 | T1047 | punct | ", ",identified |
R61 | T1066 | T1047 | nsubj | we,identified |
R62 | T1067 | T1068 | det | a,mutation |
R63 | T1068 | T1047 | dobj | mutation,identified |
R64 | T1069 | T1070 | dep | that,causes |
R65 | T1070 | T1068 | relcl | causes,mutation |
R66 | T1071 | T1072 | amod | pulmonary,hypoplasia |
R67 | T1072 | T1070 | dobj | hypoplasia,causes |
R68 | T1073 | T1072 | cc | and,hypoplasia |
R69 | T1074 | T1075 | amod | abnormal,development |
R72 | T1077 | T1047 | punct | .,identified |
R73 | T1079 | T1080 | nsubj | Fog2,maps |
R74 | T1081 | T1082 | punct | (,Zfpm2 |
R75 | T1082 | T1079 | parataxis | Zfpm2,Fog2 |
R76 | T1083 | T1082 | punct | ),Zfpm2 |
R77 | T1084 | T1080 | prep | within,maps |
R78 | T1085 | T1086 | det | the,interval |
R81 | T1088 | T1086 | acl | carrying,interval |
R82 | T1089 | T1090 | det | the,mutation |
R85 | T1092 | T1094 | npadvmod | ethyl,induced |
R93 | T1100 | T1080 | punct | ", ",maps |
R94 | T1101 | T1080 | cc | and,maps |
R95 | T1102 | T1103 | compound | DNA,sequencing |
R96 | T1103 | T1104 | nsubj | sequencing,identified |
R100 | T1107 | T1108 | det | a,mutation |
R101 | T1108 | T1104 | dobj | mutation,identified |
R102 | T1109 | T1104 | prep | in,identified |
R103 | T1110 | T1111 | det | a,site |
R107 | T1114 | T1115 | dep | that,generates |
R108 | T1115 | T1111 | relcl | generates,site |
R109 | T1116 | T1117 | det | an,transcript |
R112 | T1119 | T1117 | acl | encoding,transcript |
R113 | T1120 | T1121 | det | a,protein |
R116 | T1123 | T1104 | punct | .,identified |
R117 | T1125 | T1126 | amod | Human,cases |
R120 | T1129 | T1126 | prep | with,cases |
R121 | T1130 | T1131 | amod | diaphragmatic,defect |
R122 | T1131 | T1129 | pobj | defect,with |
R123 | T1132 | T1131 | cc | and,defect |
R124 | T1133 | T1134 | amod | pulmonary,hypoplasia |
R125 | T1134 | T1131 | conj | hypoplasia,defect |
R126 | T1135 | T1128 | auxpass | were,evaluated |
R127 | T1136 | T1128 | prep | for,evaluated |
R128 | T1137 | T1136 | pobj | mutations,for |
R129 | T1138 | T1137 | prep | in,mutations |
R130 | T1139 | T1138 | pobj | FOG2,in |
R131 | T1140 | T1128 | punct | .,evaluated |
R132 | T1142 | T1143 | compound | Sequence,analysis |
R133 | T1143 | T1144 | nsubj | analysis,revealed |
R134 | T1145 | T1146 | det | a,mutation |
R138 | T1149 | T1146 | acl | resulting,mutation |
R139 | T1150 | T1149 | prep | in,resulting |
R140 | T1151 | T1152 | det | a,codon |
R144 | T1155 | T1152 | prep | in,codon |
R145 | T1156 | T1157 | det | a,child |
R146 | T1157 | T1155 | pobj | child,in |
R147 | T1158 | T1159 | dep | who,died |
R148 | T1159 | T1157 | relcl | died,child |
R149 | T1160 | T1159 | prep | on,died |
R150 | T1161 | T1162 | det | the,day |
R153 | T1164 | T1162 | prep | of,day |
R154 | T1165 | T1164 | pobj | life,of |
R155 | T1166 | T1152 | amod | secondary,codon |
R156 | T1167 | T1166 | prep | to,secondary |
R157 | T1168 | T1169 | amod | severe,hypoplasia |
R161 | T1172 | T1169 | cc | and,hypoplasia |
R162 | T1173 | T1174 | det | an,diaphragm |
R166 | T1177 | T1144 | punct | .,revealed |
R167 | T1179 | T1180 | advcl | Using,established |
R168 | T1181 | T1182 | det | a,approach |
R171 | T1184 | T1182 | amod | driven,approach |
R173 | T1186 | T1180 | punct | ", ",established |
R174 | T1187 | T1180 | nsubj | we,established |
R175 | T1188 | T1180 | aux | have,established |
R176 | T1189 | T1190 | mark | that,required |
R180 | T1193 | T1190 | prep | for,required |
R181 | T1194 | T1195 | amod | normal,development |
R186 | T1199 | T1190 | punct | ", ",required |
R187 | T1200 | T1201 | det | a,role |
R188 | T1201 | T1190 | npadvmod | role,required |
R189 | T1202 | T1203 | dep | that,appreciated |
R195 | T1208 | T1180 | punct | .,established |
R196 | T1210 | T1211 | nsubj | FOG2,is |
R197 | T1212 | T1213 | det | the,gene |
R200 | T1215 | T1213 | acl | implicated,gene |
R201 | T1216 | T1215 | prep | in,implicated |
R202 | T1217 | T1218 | det | the,pathogenesis |
R203 | T1218 | T1216 | pobj | pathogenesis,in |
R204 | T1219 | T1218 | prep | of,pathogenesis |
R205 | T1220 | T1221 | amod | nonsyndromic,defects |
R210 | T1225 | T1211 | punct | ", ",is |
R211 | T1226 | T1211 | cc | and,is |
R212 | T1227 | T1228 | poss | its,necessity |
R213 | T1228 | T1229 | nsubj | necessity,validates |
R218 | T1233 | T1234 | det | the,hypothesis |
R219 | T1234 | T1229 | dobj | hypothesis,validates |
R220 | T1235 | T1236 | mark | that,have |
R225 | T1240 | T1238 | pobj | hernia,with |
R229 | T1244 | T1245 | amod | primary,abnormalities |
R233 | T1248 | T1229 | punct | .,validates |