Id |
Subject |
Object |
Predicate |
Lexical cue |
T726 |
11-18 |
NNS |
denotes |
Animals |
T727 |
19-22 |
VBP |
denotes |
use |
T728 |
23-26 |
DT |
denotes |
the |
T729 |
37-43 |
NN |
denotes |
system |
T730 |
27-36 |
JJ |
denotes |
gustatory |
T731 |
44-46 |
TO |
denotes |
to |
T732 |
47-54 |
VB |
denotes |
provide |
T733 |
55-66 |
NN |
denotes |
information |
T734 |
67-72 |
IN |
denotes |
about |
T735 |
73-77 |
NN |
denotes |
food |
T736 |
78-85 |
NN |
denotes |
quality |
T737 |
85-86 |
. |
denotes |
. |
T738 |
86-256 |
sentence |
denotes |
For example, sweet-tasting foods may have a high caloric content and are preferred, while bitter-tasting foods often contain toxic substances, and are generally avoided. |
T739 |
87-90 |
IN |
denotes |
For |
T740 |
124-128 |
VB |
denotes |
have |
T741 |
91-98 |
NN |
denotes |
example |
T742 |
98-100 |
, |
denotes |
, |
T743 |
100-105 |
JJ |
denotes |
sweet |
T744 |
106-113 |
VBG |
denotes |
tasting |
T745 |
105-106 |
HYPH |
denotes |
- |
T746 |
114-119 |
NNS |
denotes |
foods |
T747 |
120-123 |
MD |
denotes |
may |
T748 |
129-130 |
DT |
denotes |
a |
T749 |
144-151 |
NN |
denotes |
content |
T750 |
131-135 |
JJ |
denotes |
high |
T751 |
136-143 |
JJ |
denotes |
caloric |
T752 |
152-155 |
CC |
denotes |
and |
T753 |
156-159 |
VBP |
denotes |
are |
T754 |
160-169 |
VBN |
denotes |
preferred |
T755 |
169-171 |
, |
denotes |
, |
T756 |
171-176 |
IN |
denotes |
while |
T757 |
204-211 |
VBP |
denotes |
contain |
T758 |
177-183 |
JJ |
denotes |
bitter |
T759 |
184-191 |
VBG |
denotes |
tasting |
T760 |
183-184 |
HYPH |
denotes |
- |
T761 |
192-197 |
NNS |
denotes |
foods |
T762 |
198-203 |
RB |
denotes |
often |
T763 |
212-217 |
JJ |
denotes |
toxic |
T764 |
218-228 |
NNS |
denotes |
substances |
T765 |
228-230 |
, |
denotes |
, |
T766 |
230-233 |
CC |
denotes |
and |
T767 |
234-237 |
VBP |
denotes |
are |
T768 |
248-255 |
VBN |
denotes |
avoided |
T769 |
238-247 |
RB |
denotes |
generally |
T770 |
255-256 |
. |
denotes |
. |
T771 |
256-596 |
sentence |
denotes |
Two families of G protein-coupled receptors (GPCRs) expressed in subpopulations of taste receptor cells (TRCs) of the gustatory epithelium have been implicated in the detection and transduction of sweet, bitter and umami (i.e., glutamate) taste: T1Rs for sweet-and umami-tasting stimuli [1-8], and T2Rs for bitter-tasting compounds [9-11]. |
T772 |
257-260 |
CD |
denotes |
Two |
T773 |
261-269 |
NNS |
denotes |
families |
T774 |
406-416 |
VBN |
denotes |
implicated |
T775 |
270-272 |
IN |
denotes |
of |
T776 |
273-274 |
NN |
denotes |
G |
T777 |
275-282 |
NN |
denotes |
protein |
T778 |
283-290 |
VBN |
denotes |
coupled |
T779 |
282-283 |
HYPH |
denotes |
- |
T780 |
291-300 |
NNS |
denotes |
receptors |
T781 |
301-302 |
-LRB- |
denotes |
( |
T782 |
302-307 |
NNS |
denotes |
GPCRs |
T783 |
307-308 |
-RRB- |
denotes |
) |
T784 |
309-318 |
VBN |
denotes |
expressed |
T785 |
319-321 |
IN |
denotes |
in |
T786 |
322-336 |
NNS |
denotes |
subpopulations |
T787 |
337-339 |
IN |
denotes |
of |
T788 |
340-345 |
NN |
denotes |
taste |
T789 |
355-360 |
NNS |
denotes |
cells |
T790 |
346-354 |
NN |
denotes |
receptor |
T791 |
361-362 |
-LRB- |
denotes |
( |
T792 |
362-366 |
NNS |
denotes |
TRCs |
T793 |
366-367 |
-RRB- |
denotes |
) |
T794 |
368-370 |
IN |
denotes |
of |
T795 |
371-374 |
DT |
denotes |
the |
T796 |
385-395 |
NN |
denotes |
epithelium |
T797 |
375-384 |
JJ |
denotes |
gustatory |
T798 |
396-400 |
VBP |
denotes |
have |
T799 |
401-405 |
VBN |
denotes |
been |
T800 |
417-419 |
IN |
denotes |
in |
T801 |
420-423 |
DT |
denotes |
the |
T802 |
424-433 |
NN |
denotes |
detection |
T803 |
434-437 |
CC |
denotes |
and |
T804 |
438-450 |
NN |
denotes |
transduction |
T805 |
451-453 |
IN |
denotes |
of |
T806 |
454-459 |
JJ |
denotes |
sweet |
T807 |
496-501 |
NN |
denotes |
taste |
T808 |
459-461 |
, |
denotes |
, |
T809 |
461-467 |
JJ |
denotes |
bitter |
T810 |
468-471 |
CC |
denotes |
and |
T811 |
472-477 |
NN |
denotes |
umami |
T812 |
478-479 |
-LRB- |
denotes |
( |
T813 |
485-494 |
NN |
denotes |
glutamate |
T814 |
479-483 |
FW |
denotes |
i.e. |
T815 |
483-485 |
, |
denotes |
, |
T816 |
494-495 |
-RRB- |
denotes |
) |
T817 |
501-503 |
: |
denotes |
: |
T818 |
503-507 |
NNS |
denotes |
T1Rs |
T819 |
508-511 |
IN |
denotes |
for |
T820 |
512-517 |
JJ |
denotes |
sweet |
T821 |
536-543 |
NNS |
denotes |
stimuli |
T822 |
517-518 |
HYPH |
denotes |
- |
T823 |
518-521 |
CC |
denotes |
and |
T824 |
522-527 |
JJ |
denotes |
umami |
T825 |
528-535 |
VBG |
denotes |
tasting |
T826 |
527-528 |
HYPH |
denotes |
- |
T827 |
544-545 |
-LRB- |
denotes |
[ |
T828 |
545-546 |
CD |
denotes |
1 |
T829 |
546-547 |
SYM |
denotes |
- |
T830 |
547-548 |
CD |
denotes |
8 |
T831 |
548-549 |
-RRB- |
denotes |
] |
T832 |
549-551 |
, |
denotes |
, |
T833 |
551-554 |
CC |
denotes |
and |
T834 |
555-559 |
NNS |
denotes |
T2Rs |
T835 |
560-563 |
IN |
denotes |
for |
T836 |
564-570 |
JJ |
denotes |
bitter |
T837 |
571-578 |
VBG |
denotes |
tasting |
T838 |
570-571 |
HYPH |
denotes |
- |
T839 |
579-588 |
NNS |
denotes |
compounds |
T840 |
589-590 |
-LRB- |
denotes |
[ |
T841 |
590-591 |
CD |
denotes |
9 |
T842 |
591-592 |
SYM |
denotes |
- |
T843 |
592-594 |
CD |
denotes |
11 |
T844 |
594-595 |
-RRB- |
denotes |
] |
T845 |
595-596 |
. |
denotes |
. |
T846 |
596-795 |
sentence |
denotes |
The genes that encode T2Rs, the Tas2rs, were first identified by database mining of mammalian genomes near chromosomal markers previously linked to differences in bitter taste sensitivity [9,11-18]. |
T847 |
597-600 |
DT |
denotes |
The |
T848 |
601-606 |
NNS |
denotes |
genes |
T849 |
648-658 |
VBN |
denotes |
identified |
T850 |
607-611 |
WDT |
denotes |
that |
T851 |
612-618 |
VBP |
denotes |
encode |
T852 |
619-623 |
NNS |
denotes |
T2Rs |
T853 |
623-625 |
, |
denotes |
, |
T854 |
625-628 |
DT |
denotes |
the |
T855 |
629-635 |
NNS |
denotes |
Tas2rs |
T856 |
635-637 |
, |
denotes |
, |
T857 |
637-641 |
VBD |
denotes |
were |
T858 |
642-647 |
RB |
denotes |
first |
T859 |
659-661 |
IN |
denotes |
by |
T860 |
662-670 |
NN |
denotes |
database |
T861 |
671-677 |
NN |
denotes |
mining |
T862 |
678-680 |
IN |
denotes |
of |
T863 |
681-690 |
JJ |
denotes |
mammalian |
T864 |
691-698 |
NNS |
denotes |
genomes |
T865 |
699-703 |
IN |
denotes |
near |
T866 |
704-715 |
JJ |
denotes |
chromosomal |
T867 |
716-723 |
NNS |
denotes |
markers |
T868 |
724-734 |
RB |
denotes |
previously |
T869 |
735-741 |
VBN |
denotes |
linked |
T870 |
742-744 |
IN |
denotes |
to |
T871 |
745-756 |
NNS |
denotes |
differences |
T872 |
757-759 |
IN |
denotes |
in |
T873 |
760-766 |
JJ |
denotes |
bitter |
T874 |
767-772 |
NN |
denotes |
taste |
T875 |
773-784 |
NN |
denotes |
sensitivity |
T876 |
785-786 |
-LRB- |
denotes |
[ |
T877 |
788-790 |
CD |
denotes |
11 |
T878 |
786-787 |
CD |
denotes |
9 |
T879 |
787-788 |
, |
denotes |
, |
T880 |
790-791 |
SYM |
denotes |
- |
T881 |
791-793 |
CD |
denotes |
18 |
T882 |
793-794 |
-RRB- |
denotes |
] |
T883 |
794-795 |
. |
denotes |
. |
T884 |
795-879 |
sentence |
denotes |
In mice, the majority of Tas2rs lie within a single cluster on distal chromosome 6. |
T885 |
796-798 |
IN |
denotes |
In |
T886 |
828-831 |
VBP |
denotes |
lie |
T887 |
799-803 |
NNS |
denotes |
mice |
T888 |
803-805 |
, |
denotes |
, |
T889 |
805-808 |
DT |
denotes |
the |
T890 |
809-817 |
NN |
denotes |
majority |
T891 |
818-820 |
IN |
denotes |
of |
T892 |
821-827 |
NNS |
denotes |
Tas2rs |
T893 |
832-838 |
IN |
denotes |
within |
T894 |
839-840 |
DT |
denotes |
a |
T895 |
848-855 |
NN |
denotes |
cluster |
T896 |
841-847 |
JJ |
denotes |
single |
T897 |
856-858 |
IN |
denotes |
on |
T898 |
859-865 |
JJ |
denotes |
distal |
T899 |
866-876 |
NN |
denotes |
chromosome |
T900 |
877-878 |
CD |
denotes |
6 |
T901 |
878-879 |
. |
denotes |
. |
T902 |
879-1234 |
sentence |
denotes |
Thirty-three human Tas2rs (including 8 pseudogenes) and thirty-six mouse Tas2rs (including 3 pseudogenes in C57BL/6J mice) have been identified [9,11,19], and several of these respond to particular bitter stimuli in heterologous expression assays [10,20-23], or represent a strong candidate gene for a specific bitter taste quantitative trait [18,24,25]. |
T903 |
880-886 |
CD |
denotes |
Thirty |
T904 |
887-892 |
CD |
denotes |
three |
T905 |
886-887 |
HYPH |
denotes |
- |
T906 |
899-905 |
NNS |
denotes |
Tas2rs |
T907 |
893-898 |
JJ |
denotes |
human |
T908 |
1013-1023 |
VBN |
denotes |
identified |
T909 |
906-907 |
-LRB- |
denotes |
( |
T910 |
907-916 |
VBG |
denotes |
including |
T911 |
917-918 |
CD |
denotes |
8 |
T912 |
919-930 |
NNS |
denotes |
pseudogenes |
T913 |
930-931 |
-RRB- |
denotes |
) |
T914 |
932-935 |
CC |
denotes |
and |
T915 |
936-942 |
CD |
denotes |
thirty |
T916 |
943-946 |
CD |
denotes |
six |
T917 |
942-943 |
HYPH |
denotes |
- |
T918 |
953-959 |
NNS |
denotes |
Tas2rs |
T919 |
947-952 |
NN |
denotes |
mouse |
T920 |
960-961 |
-LRB- |
denotes |
( |
T921 |
961-970 |
VBG |
denotes |
including |
T922 |
971-972 |
CD |
denotes |
3 |
T923 |
973-984 |
NNS |
denotes |
pseudogenes |
T924 |
985-987 |
IN |
denotes |
in |
T925 |
988-993 |
NN |
denotes |
C57BL |
T926 |
994-996 |
NN |
denotes |
6J |
T927 |
993-994 |
HYPH |
denotes |
/ |
T928 |
997-1001 |
NNS |
denotes |
mice |
T929 |
1001-1002 |
-RRB- |
denotes |
) |
T930 |
1003-1007 |
VBP |
denotes |
have |
T931 |
1008-1012 |
VBN |
denotes |
been |
T932 |
1024-1025 |
-LRB- |
denotes |
[ |
T933 |
1030-1032 |
CD |
denotes |
19 |
T934 |
1025-1026 |
CD |
denotes |
9 |
T935 |
1026-1027 |
, |
denotes |
, |
T936 |
1027-1029 |
CD |
denotes |
11 |
T937 |
1029-1030 |
, |
denotes |
, |
T938 |
1032-1033 |
-RRB- |
denotes |
] |
T939 |
1033-1035 |
, |
denotes |
, |
T940 |
1035-1038 |
CC |
denotes |
and |
T941 |
1039-1046 |
JJ |
denotes |
several |
T942 |
1056-1063 |
VBP |
denotes |
respond |
T943 |
1047-1049 |
IN |
denotes |
of |
T944 |
1050-1055 |
DT |
denotes |
these |
T945 |
1064-1066 |
IN |
denotes |
to |
T946 |
1067-1077 |
JJ |
denotes |
particular |
T947 |
1085-1092 |
NNS |
denotes |
stimuli |
T948 |
1078-1084 |
JJ |
denotes |
bitter |
T949 |
1093-1095 |
IN |
denotes |
in |
T950 |
1096-1108 |
JJ |
denotes |
heterologous |
T951 |
1120-1126 |
NNS |
denotes |
assays |
T952 |
1109-1119 |
NN |
denotes |
expression |
T953 |
1127-1128 |
-LRB- |
denotes |
[ |
T954 |
1131-1133 |
CD |
denotes |
20 |
T955 |
1128-1130 |
CD |
denotes |
10 |
T956 |
1130-1131 |
, |
denotes |
, |
T957 |
1133-1134 |
SYM |
denotes |
- |
T958 |
1134-1136 |
CD |
denotes |
23 |
T959 |
1136-1137 |
-RRB- |
denotes |
] |
T960 |
1137-1139 |
, |
denotes |
, |
T961 |
1139-1141 |
CC |
denotes |
or |
T962 |
1142-1151 |
VBP |
denotes |
represent |
T963 |
1152-1153 |
DT |
denotes |
a |
T964 |
1171-1175 |
NN |
denotes |
gene |
T965 |
1154-1160 |
JJ |
denotes |
strong |
T966 |
1161-1170 |
NN |
denotes |
candidate |
T967 |
1176-1179 |
IN |
denotes |
for |
T968 |
1180-1181 |
DT |
denotes |
a |
T969 |
1217-1222 |
NN |
denotes |
trait |
T970 |
1182-1190 |
JJ |
denotes |
specific |
T971 |
1191-1197 |
JJ |
denotes |
bitter |
T972 |
1198-1203 |
NN |
denotes |
taste |
T973 |
1204-1216 |
JJ |
denotes |
quantitative |
T974 |
1223-1224 |
-LRB- |
denotes |
[ |
T975 |
1230-1232 |
CD |
denotes |
25 |
T976 |
1224-1226 |
CD |
denotes |
18 |
T977 |
1226-1227 |
, |
denotes |
, |
T978 |
1227-1229 |
CD |
denotes |
24 |
T979 |
1229-1230 |
, |
denotes |
, |
T980 |
1232-1233 |
-RRB- |
denotes |
] |
T981 |
1233-1234 |
. |
denotes |
. |
T982 |
1234-1482 |
sentence |
denotes |
Several quantitative trait loci (QTL) have been identified that influence two-bottle intake of bitter stimuli in the mouse, including loci for quinine (Qui) [12,16,26], cyclohexamide (Cyx) [13] and sucrose octaacetate (Soa) [14,15,17] sensitivity. |
T983 |
1235-1242 |
JJ |
denotes |
Several |
T984 |
1262-1266 |
NNS |
denotes |
loci |
T985 |
1243-1255 |
JJ |
denotes |
quantitative |
T986 |
1256-1261 |
NN |
denotes |
trait |
T987 |
1283-1293 |
VBN |
denotes |
identified |
T988 |
1267-1268 |
-LRB- |
denotes |
( |
T989 |
1268-1271 |
NN |
denotes |
QTL |
T990 |
1271-1272 |
-RRB- |
denotes |
) |
T991 |
1273-1277 |
VBP |
denotes |
have |
T992 |
1278-1282 |
VBN |
denotes |
been |
T993 |
1294-1298 |
WDT |
denotes |
that |
T994 |
1299-1308 |
VBP |
denotes |
influence |
T995 |
1309-1312 |
CD |
denotes |
two |
T996 |
1313-1319 |
NN |
denotes |
bottle |
T997 |
1312-1313 |
HYPH |
denotes |
- |
T998 |
1320-1326 |
NN |
denotes |
intake |
T999 |
1327-1329 |
IN |
denotes |
of |
T1000 |
1330-1336 |
JJ |
denotes |
bitter |
T1001 |
1337-1344 |
NNS |
denotes |
stimuli |
T1002 |
1345-1347 |
IN |
denotes |
in |
T1003 |
1348-1351 |
DT |
denotes |
the |
T1004 |
1352-1357 |
NN |
denotes |
mouse |
T1005 |
1357-1359 |
, |
denotes |
, |
T1006 |
1359-1368 |
VBG |
denotes |
including |
T1007 |
1369-1373 |
NNS |
denotes |
loci |
T1008 |
1374-1377 |
IN |
denotes |
for |
T1009 |
1378-1385 |
NN |
denotes |
quinine |
T1010 |
1470-1481 |
NN |
denotes |
sensitivity |
T1011 |
1386-1387 |
-LRB- |
denotes |
( |
T1012 |
1387-1390 |
NN |
denotes |
Qui |
T1013 |
1390-1391 |
-RRB- |
denotes |
) |
T1014 |
1392-1393 |
-LRB- |
denotes |
[ |
T1015 |
1399-1401 |
CD |
denotes |
26 |
T1016 |
1393-1395 |
CD |
denotes |
12 |
T1017 |
1395-1396 |
, |
denotes |
, |
T1018 |
1396-1398 |
CD |
denotes |
16 |
T1019 |
1398-1399 |
, |
denotes |
, |
T1020 |
1401-1402 |
-RRB- |
denotes |
] |
T1021 |
1402-1404 |
, |
denotes |
, |
T1022 |
1404-1417 |
NN |
denotes |
cyclohexamide |
T1023 |
1418-1419 |
-LRB- |
denotes |
( |
T1024 |
1419-1422 |
NN |
denotes |
Cyx |
T1025 |
1422-1423 |
-RRB- |
denotes |
) |
T1026 |
1424-1425 |
-LRB- |
denotes |
[ |
T1027 |
1425-1427 |
CD |
denotes |
13 |
T1028 |
1427-1428 |
-RRB- |
denotes |
] |
T1029 |
1429-1432 |
CC |
denotes |
and |
T1030 |
1433-1440 |
NN |
denotes |
sucrose |
T1031 |
1441-1452 |
NN |
denotes |
octaacetate |
T1032 |
1453-1454 |
-LRB- |
denotes |
( |
T1033 |
1454-1457 |
NN |
denotes |
Soa |
T1034 |
1457-1458 |
-RRB- |
denotes |
) |
T1035 |
1459-1460 |
-LRB- |
denotes |
[ |
T1036 |
1466-1468 |
CD |
denotes |
17 |
T1037 |
1460-1462 |
CD |
denotes |
14 |
T1038 |
1462-1463 |
, |
denotes |
, |
T1039 |
1463-1465 |
CD |
denotes |
15 |
T1040 |
1465-1466 |
, |
denotes |
, |
T1041 |
1468-1469 |
-RRB- |
denotes |
] |
T1042 |
1481-1482 |
. |
denotes |
. |
T1043 |
1482-1661 |
sentence |
denotes |
Each of these QTL map to mouse distal chromosome 6 and are linked to the marker D6Mit13, which lies within a cluster of 24 intact Tas2rs in the C57BL/6 genome (e.g., [16,27,28]). |
T1044 |
1483-1487 |
DT |
denotes |
Each |
T1045 |
1501-1504 |
VBP |
denotes |
map |
T1046 |
1488-1490 |
IN |
denotes |
of |
T1047 |
1491-1496 |
DT |
denotes |
these |
T1048 |
1497-1500 |
NN |
denotes |
QTL |
T1049 |
1505-1507 |
IN |
denotes |
to |
T1050 |
1508-1513 |
NN |
denotes |
mouse |
T1051 |
1521-1531 |
NN |
denotes |
chromosome |
T1052 |
1514-1520 |
JJ |
denotes |
distal |
T1053 |
1532-1533 |
CD |
denotes |
6 |
T1054 |
1534-1537 |
CC |
denotes |
and |
T1055 |
1538-1541 |
VBP |
denotes |
are |
T1056 |
1542-1548 |
VBN |
denotes |
linked |
T1057 |
1549-1551 |
IN |
denotes |
to |
T1058 |
1552-1555 |
DT |
denotes |
the |
T1059 |
1563-1570 |
NN |
denotes |
D6Mit13 |
T1060 |
1556-1562 |
NN |
denotes |
marker |
T1061 |
1570-1572 |
, |
denotes |
, |
T1062 |
1572-1577 |
WDT |
denotes |
which |
T1063 |
1578-1582 |
VBZ |
denotes |
lies |
T1064 |
1583-1589 |
IN |
denotes |
within |
T1065 |
1590-1591 |
DT |
denotes |
a |
T1066 |
1592-1599 |
NN |
denotes |
cluster |
T1067 |
1600-1602 |
IN |
denotes |
of |
T1068 |
1603-1605 |
CD |
denotes |
24 |
T1069 |
1613-1619 |
NNS |
denotes |
Tas2rs |
T1070 |
1606-1612 |
JJ |
denotes |
intact |
T1071 |
1620-1622 |
IN |
denotes |
in |
T1072 |
1623-1626 |
DT |
denotes |
the |
T1073 |
1635-1641 |
NN |
denotes |
genome |
T1074 |
1627-1632 |
NN |
denotes |
C57BL |
T1075 |
1632-1633 |
HYPH |
denotes |
/ |
T1076 |
1633-1634 |
CD |
denotes |
6 |
T1077 |
1642-1643 |
-LRB- |
denotes |
( |
T1078 |
1656-1658 |
CD |
denotes |
28 |
T1079 |
1643-1647 |
FW |
denotes |
e.g. |
T1080 |
1647-1649 |
, |
denotes |
, |
T1081 |
1649-1650 |
-LRB- |
denotes |
[ |
T1082 |
1650-1652 |
CD |
denotes |
16 |
T1083 |
1652-1653 |
, |
denotes |
, |
T1084 |
1653-1655 |
CD |
denotes |
27 |
T1085 |
1655-1656 |
, |
denotes |
, |
T1086 |
1658-1659 |
-RRB- |
denotes |
] |
T1087 |
1659-1660 |
-RRB- |
denotes |
) |
T1088 |
1660-1661 |
. |
denotes |
. |
T1089 |
1661-1743 |
sentence |
denotes |
However, the interpretation of these studies remains problematic for two reasons. |
T1090 |
1662-1669 |
RB |
denotes |
However |
T1091 |
1707-1714 |
VBZ |
denotes |
remains |
T1092 |
1669-1671 |
, |
denotes |
, |
T1093 |
1671-1674 |
DT |
denotes |
the |
T1094 |
1675-1689 |
NN |
denotes |
interpretation |
T1095 |
1690-1692 |
IN |
denotes |
of |
T1096 |
1693-1698 |
DT |
denotes |
these |
T1097 |
1699-1706 |
NNS |
denotes |
studies |
T1098 |
1715-1726 |
JJ |
denotes |
problematic |
T1099 |
1727-1730 |
IN |
denotes |
for |
T1100 |
1731-1734 |
CD |
denotes |
two |
T1101 |
1735-1742 |
NNS |
denotes |
reasons |
T1102 |
1742-1743 |
. |
denotes |
. |
T1103 |
1743-1938 |
sentence |
denotes |
First, the density of chromosomal markers and number of recombinant inbred (RI) strains used in these earlier studies did not permit the physical definition of the intervals containing each QTL. |
T1104 |
1744-1749 |
RB |
denotes |
First |
T1105 |
1870-1876 |
VB |
denotes |
permit |
T1106 |
1749-1751 |
, |
denotes |
, |
T1107 |
1751-1754 |
DT |
denotes |
the |
T1108 |
1755-1762 |
NN |
denotes |
density |
T1109 |
1763-1765 |
IN |
denotes |
of |
T1110 |
1766-1777 |
JJ |
denotes |
chromosomal |
T1111 |
1778-1785 |
NNS |
denotes |
markers |
T1112 |
1786-1789 |
CC |
denotes |
and |
T1113 |
1790-1796 |
NN |
denotes |
number |
T1114 |
1797-1799 |
IN |
denotes |
of |
T1115 |
1800-1811 |
JJ |
denotes |
recombinant |
T1116 |
1812-1818 |
JJ |
denotes |
inbred |
T1117 |
1820-1822 |
JJ |
denotes |
RI |
T1118 |
1819-1820 |
-LRB- |
denotes |
( |
T1119 |
1824-1831 |
NNS |
denotes |
strains |
T1120 |
1822-1823 |
-RRB- |
denotes |
) |
T1121 |
1832-1836 |
VBN |
denotes |
used |
T1122 |
1837-1839 |
IN |
denotes |
in |
T1123 |
1840-1845 |
DT |
denotes |
these |
T1124 |
1854-1861 |
NNS |
denotes |
studies |
T1125 |
1846-1853 |
JJR |
denotes |
earlier |
T1126 |
1862-1865 |
VBD |
denotes |
did |
T1127 |
1866-1869 |
RB |
denotes |
not |
T1128 |
1877-1880 |
DT |
denotes |
the |
T1129 |
1890-1900 |
NN |
denotes |
definition |
T1130 |
1881-1889 |
JJ |
denotes |
physical |
T1131 |
1901-1903 |
IN |
denotes |
of |
T1132 |
1904-1907 |
DT |
denotes |
the |
T1133 |
1908-1917 |
NNS |
denotes |
intervals |
T1134 |
1918-1928 |
VBG |
denotes |
containing |
T1135 |
1929-1933 |
DT |
denotes |
each |
T1136 |
1934-1937 |
NN |
denotes |
QTL |
T1137 |
1937-1938 |
. |
denotes |
. |
T1138 |
1938-2137 |
sentence |
denotes |
Second, these previous attempts to map bitter taste QTLs relied on behavioral assays that measured consumption, and were thus susceptible to contributions of post-ingestive effects such as toxicity. |
T1139 |
1939-1945 |
RB |
denotes |
Second |
T1140 |
1996-2002 |
VBD |
denotes |
relied |
T1141 |
1945-1947 |
, |
denotes |
, |
T1142 |
1947-1952 |
DT |
denotes |
these |
T1143 |
1962-1970 |
NNS |
denotes |
attempts |
T1144 |
1953-1961 |
JJ |
denotes |
previous |
T1145 |
1971-1973 |
TO |
denotes |
to |
T1146 |
1974-1977 |
VB |
denotes |
map |
T1147 |
1978-1984 |
JJ |
denotes |
bitter |
T1148 |
1985-1990 |
NN |
denotes |
taste |
T1149 |
1991-1995 |
NNS |
denotes |
QTLs |
T1150 |
2003-2005 |
IN |
denotes |
on |
T1151 |
2006-2016 |
JJ |
denotes |
behavioral |
T1152 |
2017-2023 |
NNS |
denotes |
assays |
T1153 |
2024-2028 |
WDT |
denotes |
that |
T1154 |
2029-2037 |
VBN |
denotes |
measured |
T1155 |
2038-2049 |
NN |
denotes |
consumption |
T1156 |
2049-2051 |
, |
denotes |
, |
T1157 |
2051-2054 |
CC |
denotes |
and |
T1158 |
2055-2059 |
VBD |
denotes |
were |
T1159 |
2060-2064 |
RB |
denotes |
thus |
T1160 |
2065-2076 |
JJ |
denotes |
susceptible |
T1161 |
2077-2079 |
IN |
denotes |
to |
T1162 |
2080-2093 |
NNS |
denotes |
contributions |
T1163 |
2094-2096 |
IN |
denotes |
of |
T1164 |
2097-2111 |
JJ |
denotes |
post-ingestive |
T1165 |
2112-2119 |
NNS |
denotes |
effects |
T1166 |
2120-2124 |
JJ |
denotes |
such |
T1167 |
2125-2127 |
IN |
denotes |
as |
T1168 |
2128-2136 |
NN |
denotes |
toxicity |
T1169 |
2136-2137 |
. |
denotes |
. |
T1170 |
2137-2243 |
sentence |
denotes |
As we have shown previously, such effects can confound the quantification of bitter taste behaviors [29]. |
T1171 |
2138-2140 |
IN |
denotes |
As |
T1172 |
2149-2154 |
VBN |
denotes |
shown |
T1173 |
2141-2143 |
PRP |
denotes |
we |
T1174 |
2144-2148 |
VBP |
denotes |
have |
T1175 |
2184-2192 |
VB |
denotes |
confound |
T1176 |
2155-2165 |
RB |
denotes |
previously |
T1177 |
2165-2167 |
, |
denotes |
, |
T1178 |
2167-2171 |
JJ |
denotes |
such |
T1179 |
2172-2179 |
NNS |
denotes |
effects |
T1180 |
2180-2183 |
MD |
denotes |
can |
T1181 |
2193-2196 |
DT |
denotes |
the |
T1182 |
2197-2211 |
NN |
denotes |
quantification |
T1183 |
2212-2214 |
IN |
denotes |
of |
T1184 |
2215-2221 |
JJ |
denotes |
bitter |
T1185 |
2222-2227 |
NN |
denotes |
taste |
T1186 |
2228-2237 |
NNS |
denotes |
behaviors |
T1187 |
2238-2239 |
-LRB- |
denotes |
[ |
T1188 |
2239-2241 |
CD |
denotes |
29 |
T1189 |
2241-2242 |
-RRB- |
denotes |
] |
T1190 |
2242-2243 |
. |
denotes |
. |
T1191 |
2243-2347 |
sentence |
denotes |
Therefore, the relevance and/or contribution of the aforementioned QTLs to bitter taste remain unclear. |
T1192 |
2244-2253 |
RB |
denotes |
Therefore |
T1193 |
2332-2338 |
VBP |
denotes |
remain |
T1194 |
2253-2255 |
, |
denotes |
, |
T1195 |
2255-2258 |
DT |
denotes |
the |
T1196 |
2259-2268 |
NN |
denotes |
relevance |
T1197 |
2269-2272 |
CC |
denotes |
and |
T1198 |
2272-2273 |
HYPH |
denotes |
/ |
T1199 |
2273-2275 |
CC |
denotes |
or |
T1200 |
2276-2288 |
NN |
denotes |
contribution |
T1201 |
2289-2291 |
IN |
denotes |
of |
T1202 |
2292-2295 |
DT |
denotes |
the |
T1203 |
2311-2315 |
NNS |
denotes |
QTLs |
T1204 |
2296-2310 |
JJ |
denotes |
aforementioned |
T1205 |
2316-2318 |
IN |
denotes |
to |
T1206 |
2319-2325 |
JJ |
denotes |
bitter |
T1207 |
2326-2331 |
NN |
denotes |
taste |
T1208 |
2339-2346 |
JJ |
denotes |
unclear |
T1209 |
2346-2347 |
. |
denotes |
. |
T1210 |
2347-2581 |
sentence |
denotes |
Furthermore, a number of physiological studies have suggested that the transduction of some amphiphilic bitter compounds, such as quinine and denatonium benzoate, may stimulate taste receptor cells independently of GPCRs (e.g. [30]). |
T1211 |
2348-2359 |
RB |
denotes |
Furthermore |
T1212 |
2400-2409 |
VBN |
denotes |
suggested |
T1213 |
2359-2361 |
, |
denotes |
, |
T1214 |
2361-2362 |
DT |
denotes |
a |
T1215 |
2363-2369 |
NN |
denotes |
number |
T1216 |
2370-2372 |
IN |
denotes |
of |
T1217 |
2373-2386 |
JJ |
denotes |
physiological |
T1218 |
2387-2394 |
NNS |
denotes |
studies |
T1219 |
2395-2399 |
VBP |
denotes |
have |
T1220 |
2410-2414 |
IN |
denotes |
that |
T1221 |
2515-2524 |
VB |
denotes |
stimulate |
T1222 |
2415-2418 |
DT |
denotes |
the |
T1223 |
2419-2431 |
NN |
denotes |
transduction |
T1224 |
2432-2434 |
IN |
denotes |
of |
T1225 |
2435-2439 |
DT |
denotes |
some |
T1226 |
2459-2468 |
NNS |
denotes |
compounds |
T1227 |
2440-2451 |
JJ |
denotes |
amphiphilic |
T1228 |
2452-2458 |
JJ |
denotes |
bitter |
T1229 |
2468-2470 |
, |
denotes |
, |
T1230 |
2470-2474 |
JJ |
denotes |
such |
T1231 |
2475-2477 |
IN |
denotes |
as |
T1232 |
2478-2485 |
NN |
denotes |
quinine |
T1233 |
2486-2489 |
CC |
denotes |
and |
T1234 |
2490-2500 |
NN |
denotes |
denatonium |
T1235 |
2501-2509 |
NN |
denotes |
benzoate |
T1236 |
2509-2511 |
, |
denotes |
, |
T1237 |
2511-2514 |
MD |
denotes |
may |
T1238 |
2525-2530 |
NN |
denotes |
taste |
T1239 |
2531-2539 |
NN |
denotes |
receptor |
T1240 |
2540-2545 |
NNS |
denotes |
cells |
T1241 |
2546-2559 |
RB |
denotes |
independently |
T1242 |
2560-2562 |
IN |
denotes |
of |
T1243 |
2563-2568 |
NNS |
denotes |
GPCRs |
T1244 |
2569-2570 |
-LRB- |
denotes |
( |
T1245 |
2576-2578 |
CD |
denotes |
30 |
T1246 |
2570-2574 |
FW |
denotes |
e.g. |
T1247 |
2575-2576 |
-LRB- |
denotes |
[ |
T1248 |
2578-2579 |
-RRB- |
denotes |
] |
T1249 |
2579-2580 |
-RRB- |
denotes |
) |
T1250 |
2580-2581 |
. |
denotes |
. |
T1251 |
2581-2787 |
sentence |
denotes |
Quinine may directly activate G proteins, and both quinine and denatonium can block K+ channels [31-36] ; caffeine, another bitter-tasting substance, directly inhibits intracellular phosphodiesterase [33]. |
T1252 |
2582-2589 |
NN |
denotes |
Quinine |
T1253 |
2603-2611 |
VB |
denotes |
activate |
T1254 |
2590-2593 |
MD |
denotes |
may |
T1255 |
2594-2602 |
RB |
denotes |
directly |
T1256 |
2741-2749 |
VBZ |
denotes |
inhibits |
T1257 |
2612-2613 |
NN |
denotes |
G |
T1258 |
2614-2622 |
NN |
denotes |
proteins |
T1259 |
2622-2624 |
, |
denotes |
, |
T1260 |
2624-2627 |
CC |
denotes |
and |
T1261 |
2628-2632 |
CC |
denotes |
both |
T1262 |
2633-2640 |
NN |
denotes |
quinine |
T1263 |
2660-2665 |
VB |
denotes |
block |
T1264 |
2641-2644 |
CC |
denotes |
and |
T1265 |
2645-2655 |
NN |
denotes |
denatonium |
T1266 |
2656-2659 |
MD |
denotes |
can |
T1267 |
2666-2667 |
NN |
denotes |
K |
T1268 |
2669-2677 |
NNS |
denotes |
channels |
T1269 |
2667-2668 |
SYM |
denotes |
+ |
T1270 |
2678-2679 |
-LRB- |
denotes |
[ |
T1271 |
2679-2681 |
CD |
denotes |
31 |
T1272 |
2681-2682 |
SYM |
denotes |
- |
T1273 |
2682-2684 |
CD |
denotes |
36 |
T1274 |
2684-2685 |
-RRB- |
denotes |
] |
T1275 |
2686-2687 |
: |
denotes |
; |
T1276 |
2688-2696 |
NN |
denotes |
caffeine |
T1277 |
2696-2698 |
, |
denotes |
, |
T1278 |
2698-2705 |
DT |
denotes |
another |
T1279 |
2721-2730 |
NN |
denotes |
substance |
T1280 |
2706-2712 |
JJ |
denotes |
bitter |
T1281 |
2713-2720 |
VBG |
denotes |
tasting |
T1282 |
2712-2713 |
HYPH |
denotes |
- |
T1283 |
2730-2732 |
, |
denotes |
, |
T1284 |
2732-2740 |
RB |
denotes |
directly |
T1285 |
2750-2763 |
JJ |
denotes |
intracellular |
T1286 |
2764-2781 |
NN |
denotes |
phosphodiesterase |
T1287 |
2782-2783 |
-LRB- |
denotes |
[ |
T1288 |
2783-2785 |
CD |
denotes |
33 |
T1289 |
2785-2786 |
-RRB- |
denotes |
] |
T1290 |
2786-2787 |
. |
denotes |
. |
T1291 |
2787-2925 |
sentence |
denotes |
However, the relative contributions of T2R-dependent and T2R-independent mechanisms to the detection of these bitter stimuli are unknown. |
T1292 |
2788-2795 |
RB |
denotes |
However |
T1293 |
2913-2916 |
VBP |
denotes |
are |
T1294 |
2795-2797 |
, |
denotes |
, |
T1295 |
2797-2800 |
DT |
denotes |
the |
T1296 |
2810-2823 |
NNS |
denotes |
contributions |
T1297 |
2801-2809 |
JJ |
denotes |
relative |
T1298 |
2824-2826 |
IN |
denotes |
of |
T1299 |
2827-2830 |
NN |
denotes |
T2R |
T1300 |
2831-2840 |
JJ |
denotes |
dependent |
T1301 |
2830-2831 |
HYPH |
denotes |
- |
T1302 |
2861-2871 |
NNS |
denotes |
mechanisms |
T1303 |
2841-2844 |
CC |
denotes |
and |
T1304 |
2845-2848 |
NN |
denotes |
T2R |
T1305 |
2849-2860 |
JJ |
denotes |
independent |
T1306 |
2848-2849 |
HYPH |
denotes |
- |
T1307 |
2872-2874 |
IN |
denotes |
to |
T1308 |
2875-2878 |
DT |
denotes |
the |
T1309 |
2879-2888 |
NN |
denotes |
detection |
T1310 |
2889-2891 |
IN |
denotes |
of |
T1311 |
2892-2897 |
DT |
denotes |
these |
T1312 |
2905-2912 |
NNS |
denotes |
stimuli |
T1313 |
2898-2904 |
JJ |
denotes |
bitter |
T1314 |
2917-2924 |
JJ |
denotes |
unknown |
T1315 |
2924-2925 |
. |
denotes |
. |
T1316 |
2925-3173 |
sentence |
denotes |
Here we use a taste-salient brief-access lick test [29,37] to measure taste sensitivities in C57BL/6J (B6), DBA/2J (D2) and BXD/Ty (BXD) recombinant inbred (RI) mice to two bitter stimuli, quinine hydrochloride (QHCl) and denatonium benzoate (DB). |
T1317 |
2926-2930 |
RB |
denotes |
Here |
T1318 |
2934-2937 |
VBP |
denotes |
use |
T1319 |
2931-2933 |
PRP |
denotes |
we |
T1320 |
2938-2939 |
DT |
denotes |
a |
T1321 |
2972-2976 |
NN |
denotes |
test |
T1322 |
2940-2945 |
NN |
denotes |
taste |
T1323 |
2946-2953 |
JJ |
denotes |
salient |
T1324 |
2945-2946 |
HYPH |
denotes |
- |
T1325 |
2954-2959 |
JJ |
denotes |
brief |
T1326 |
2960-2966 |
NN |
denotes |
access |
T1327 |
2959-2960 |
HYPH |
denotes |
- |
T1328 |
2967-2971 |
NN |
denotes |
lick |
T1329 |
2977-2978 |
-LRB- |
denotes |
[ |
T1330 |
2981-2983 |
CD |
denotes |
37 |
T1331 |
2978-2980 |
CD |
denotes |
29 |
T1332 |
2980-2981 |
, |
denotes |
, |
T1333 |
2983-2984 |
-RRB- |
denotes |
] |
T1334 |
2985-2987 |
TO |
denotes |
to |
T1335 |
2988-2995 |
VB |
denotes |
measure |
T1336 |
2996-3001 |
NN |
denotes |
taste |
T1337 |
3002-3015 |
NNS |
denotes |
sensitivities |
T1338 |
3016-3018 |
IN |
denotes |
in |
T1339 |
3019-3024 |
NN |
denotes |
C57BL |
T1340 |
3025-3027 |
NN |
denotes |
6J |
T1341 |
3024-3025 |
HYPH |
denotes |
/ |
T1342 |
3087-3091 |
NNS |
denotes |
mice |
T1343 |
3028-3029 |
-LRB- |
denotes |
( |
T1344 |
3029-3031 |
NN |
denotes |
B6 |
T1345 |
3031-3032 |
-RRB- |
denotes |
) |
T1346 |
3032-3034 |
, |
denotes |
, |
T1347 |
3034-3037 |
NN |
denotes |
DBA |
T1348 |
3038-3040 |
NN |
denotes |
2J |
T1349 |
3037-3038 |
HYPH |
denotes |
/ |
T1350 |
3041-3042 |
-LRB- |
denotes |
( |
T1351 |
3042-3044 |
NN |
denotes |
D2 |
T1352 |
3044-3045 |
-RRB- |
denotes |
) |
T1353 |
3046-3049 |
CC |
denotes |
and |
T1354 |
3050-3053 |
NN |
denotes |
BXD |
T1355 |
3054-3056 |
NN |
denotes |
Ty |
T1356 |
3053-3054 |
HYPH |
denotes |
/ |
T1357 |
3057-3058 |
-LRB- |
denotes |
( |
T1358 |
3058-3061 |
NN |
denotes |
BXD |
T1359 |
3061-3062 |
-RRB- |
denotes |
) |
T1360 |
3063-3074 |
JJ |
denotes |
recombinant |
T1361 |
3075-3081 |
JJ |
denotes |
inbred |
T1362 |
3082-3083 |
-LRB- |
denotes |
( |
T1363 |
3083-3085 |
JJ |
denotes |
RI |
T1364 |
3085-3086 |
-RRB- |
denotes |
) |
T1365 |
3092-3094 |
IN |
denotes |
to |
T1366 |
3095-3098 |
CD |
denotes |
two |
T1367 |
3106-3113 |
NNS |
denotes |
stimuli |
T1368 |
3099-3105 |
JJ |
denotes |
bitter |
T1369 |
3113-3115 |
, |
denotes |
, |
T1370 |
3115-3122 |
NN |
denotes |
quinine |
T1371 |
3123-3136 |
NN |
denotes |
hydrochloride |
T1372 |
3137-3138 |
-LRB- |
denotes |
( |
T1373 |
3138-3142 |
NN |
denotes |
QHCl |
T1374 |
3142-3143 |
-RRB- |
denotes |
) |
T1375 |
3144-3147 |
CC |
denotes |
and |
T1376 |
3148-3158 |
NN |
denotes |
denatonium |
T1377 |
3159-3167 |
NN |
denotes |
benzoate |
T1378 |
3168-3169 |
-LRB- |
denotes |
( |
T1379 |
3169-3171 |
NN |
denotes |
DB |
T1380 |
3171-3172 |
-RRB- |
denotes |
) |
T1381 |
3172-3173 |
. |
denotes |
. |
T1382 |
3173-3395 |
sentence |
denotes |
Using 17 BXD lines that were genotyped at 762 informative chromosomal markers, we mapped a major QTL for QHCl taste to a ~5 Mb interval on distal chromosome 6 that contains all 24 of the Tas2r genes in the distal cluster. |
T1383 |
3174-3179 |
VBG |
denotes |
Using |
T1384 |
3256-3262 |
VBD |
denotes |
mapped |
T1385 |
3180-3182 |
CD |
denotes |
17 |
T1386 |
3187-3192 |
NNS |
denotes |
lines |
T1387 |
3183-3186 |
NN |
denotes |
BXD |
T1388 |
3193-3197 |
WDT |
denotes |
that |
T1389 |
3203-3212 |
VBN |
denotes |
genotyped |
T1390 |
3198-3202 |
VBD |
denotes |
were |
T1391 |
3213-3215 |
IN |
denotes |
at |
T1392 |
3216-3219 |
CD |
denotes |
762 |
T1393 |
3244-3251 |
NNS |
denotes |
markers |
T1394 |
3220-3231 |
JJ |
denotes |
informative |
T1395 |
3232-3243 |
JJ |
denotes |
chromosomal |
T1396 |
3251-3253 |
, |
denotes |
, |
T1397 |
3253-3255 |
PRP |
denotes |
we |
T1398 |
3263-3264 |
DT |
denotes |
a |
T1399 |
3271-3274 |
NN |
denotes |
QTL |
T1400 |
3265-3270 |
JJ |
denotes |
major |
T1401 |
3275-3278 |
IN |
denotes |
for |
T1402 |
3279-3283 |
NN |
denotes |
QHCl |
T1403 |
3284-3289 |
NN |
denotes |
taste |
T1404 |
3290-3292 |
IN |
denotes |
to |
T1405 |
3293-3294 |
DT |
denotes |
a |
T1406 |
3301-3309 |
NN |
denotes |
interval |
T1407 |
3295-3296 |
SYM |
denotes |
~ |
T1408 |
3296-3297 |
CD |
denotes |
5 |
T1409 |
3298-3300 |
NN |
denotes |
Mb |
T1410 |
3310-3312 |
IN |
denotes |
on |
T1411 |
3313-3319 |
JJ |
denotes |
distal |
T1412 |
3320-3330 |
NN |
denotes |
chromosome |
T1413 |
3331-3332 |
CD |
denotes |
6 |
T1414 |
3333-3337 |
WDT |
denotes |
that |
T1415 |
3338-3346 |
VBZ |
denotes |
contains |
T1416 |
3347-3350 |
DT |
denotes |
all |
T1417 |
3351-3353 |
CD |
denotes |
24 |
T1418 |
3354-3356 |
IN |
denotes |
of |
T1419 |
3357-3360 |
DT |
denotes |
the |
T1420 |
3367-3372 |
NNS |
denotes |
genes |
T1421 |
3361-3366 |
NN |
denotes |
Tas2r |
T1422 |
3373-3375 |
IN |
denotes |
in |
T1423 |
3376-3379 |
DT |
denotes |
the |
T1424 |
3387-3394 |
NN |
denotes |
cluster |
T1425 |
3380-3386 |
JJ |
denotes |
distal |
T1426 |
3394-3395 |
. |
denotes |
. |
T1427 |
3395-3494 |
sentence |
denotes |
We analyzed the sequence of each Tas2r allele in the parental strains (B6 and D2) and 29 RI lines. |
T1428 |
3396-3398 |
PRP |
denotes |
We |
T1429 |
3399-3407 |
VBD |
denotes |
analyzed |
T1430 |
3408-3411 |
DT |
denotes |
the |
T1431 |
3412-3420 |
NN |
denotes |
sequence |
T1432 |
3421-3423 |
IN |
denotes |
of |
T1433 |
3424-3428 |
DT |
denotes |
each |
T1434 |
3435-3441 |
NN |
denotes |
allele |
T1435 |
3429-3434 |
NN |
denotes |
Tas2r |
T1436 |
3442-3444 |
IN |
denotes |
in |
T1437 |
3445-3448 |
DT |
denotes |
the |
T1438 |
3458-3465 |
NNS |
denotes |
strains |
T1439 |
3449-3457 |
JJ |
denotes |
parental |
T1440 |
3466-3467 |
-LRB- |
denotes |
( |
T1441 |
3467-3469 |
NN |
denotes |
B6 |
T1442 |
3470-3473 |
CC |
denotes |
and |
T1443 |
3474-3476 |
NN |
denotes |
D2 |
T1444 |
3476-3477 |
-RRB- |
denotes |
) |
T1445 |
3478-3481 |
CC |
denotes |
and |
T1446 |
3482-3484 |
CD |
denotes |
29 |
T1447 |
3488-3493 |
NNS |
denotes |
lines |
T1448 |
3485-3487 |
JJ |
denotes |
RI |
T1449 |
3493-3494 |
. |
denotes |
. |
T1450 |
3494-3674 |
sentence |
denotes |
This analysis revealed that all 24 genes are polymorphic between the two strains, and that these 24 Tas2rs comprise a single haplotype that correlates with QHCl taste sensitivity. |
T1451 |
3495-3499 |
DT |
denotes |
This |
T1452 |
3500-3508 |
NN |
denotes |
analysis |
T1453 |
3509-3517 |
VBD |
denotes |
revealed |
T1454 |
3518-3522 |
IN |
denotes |
that |
T1455 |
3536-3539 |
VBP |
denotes |
are |
T1456 |
3523-3526 |
DT |
denotes |
all |
T1457 |
3530-3535 |
NNS |
denotes |
genes |
T1458 |
3527-3529 |
CD |
denotes |
24 |
T1459 |
3540-3551 |
JJ |
denotes |
polymorphic |
T1460 |
3552-3559 |
IN |
denotes |
between |
T1461 |
3560-3563 |
DT |
denotes |
the |
T1462 |
3568-3575 |
NNS |
denotes |
strains |
T1463 |
3564-3567 |
CD |
denotes |
two |
T1464 |
3575-3577 |
, |
denotes |
, |
T1465 |
3577-3580 |
CC |
denotes |
and |
T1466 |
3581-3585 |
IN |
denotes |
that |
T1467 |
3602-3610 |
VBP |
denotes |
comprise |
T1468 |
3586-3591 |
DT |
denotes |
these |
T1469 |
3595-3601 |
NNS |
denotes |
Tas2rs |
T1470 |
3592-3594 |
CD |
denotes |
24 |
T1471 |
3611-3612 |
DT |
denotes |
a |
T1472 |
3620-3629 |
NN |
denotes |
haplotype |
T1473 |
3613-3619 |
JJ |
denotes |
single |
T1474 |
3630-3634 |
WDT |
denotes |
that |
T1475 |
3635-3645 |
VBZ |
denotes |
correlates |
T1476 |
3646-3650 |
IN |
denotes |
with |
T1477 |
3651-3655 |
NN |
denotes |
QHCl |
T1478 |
3656-3661 |
NN |
denotes |
taste |
T1479 |
3662-3673 |
NN |
denotes |
sensitivity |
T1480 |
3673-3674 |
. |
denotes |
. |
R359 |
T726 |
T727 |
nsubj |
Animals,use |
R360 |
T728 |
T729 |
det |
the,system |
R361 |
T729 |
T727 |
dobj |
system,use |
R362 |
T730 |
T729 |
amod |
gustatory,system |
R363 |
T731 |
T732 |
aux |
to,provide |
R364 |
T732 |
T727 |
advcl |
provide,use |
R365 |
T733 |
T732 |
dobj |
information,provide |
R366 |
T734 |
T733 |
prep |
about,information |
R367 |
T735 |
T736 |
compound |
food,quality |
R368 |
T736 |
T734 |
pobj |
quality,about |
R369 |
T737 |
T727 |
punct |
.,use |
R370 |
T739 |
T740 |
prep |
For,have |
R371 |
T741 |
T739 |
pobj |
example,For |
R372 |
T742 |
T740 |
punct |
", ",have |
R373 |
T743 |
T744 |
amod |
sweet,tasting |
R374 |
T744 |
T746 |
amod |
tasting,foods |
R375 |
T745 |
T744 |
punct |
-,tasting |
R376 |
T746 |
T740 |
nsubj |
foods,have |
R377 |
T747 |
T740 |
aux |
may,have |
R378 |
T748 |
T749 |
det |
a,content |
R379 |
T749 |
T740 |
dobj |
content,have |
R380 |
T750 |
T749 |
amod |
high,content |
R381 |
T751 |
T749 |
amod |
caloric,content |
R382 |
T752 |
T740 |
cc |
and,have |
R383 |
T753 |
T754 |
auxpass |
are,preferred |
R384 |
T754 |
T740 |
conj |
preferred,have |
R385 |
T755 |
T740 |
punct |
", ",have |
R386 |
T756 |
T757 |
mark |
while,contain |
R387 |
T757 |
T740 |
advcl |
contain,have |
R388 |
T758 |
T759 |
amod |
bitter,tasting |
R389 |
T759 |
T761 |
amod |
tasting,foods |
R390 |
T760 |
T759 |
punct |
-,tasting |
R391 |
T761 |
T757 |
nsubj |
foods,contain |
R392 |
T762 |
T757 |
advmod |
often,contain |
R393 |
T763 |
T764 |
amod |
toxic,substances |
R394 |
T764 |
T757 |
dobj |
substances,contain |
R395 |
T765 |
T757 |
punct |
", ",contain |
R396 |
T766 |
T757 |
cc |
and,contain |
R397 |
T767 |
T768 |
auxpass |
are,avoided |
R398 |
T768 |
T757 |
conj |
avoided,contain |
R399 |
T769 |
T768 |
advmod |
generally,avoided |
R400 |
T770 |
T740 |
punct |
.,have |
R401 |
T772 |
T773 |
nummod |
Two,families |
R402 |
T773 |
T774 |
nsubjpass |
families,implicated |
R403 |
T775 |
T773 |
prep |
of,families |
R404 |
T776 |
T777 |
compound |
G,protein |
R405 |
T777 |
T778 |
npadvmod |
protein,coupled |
R406 |
T778 |
T780 |
amod |
coupled,receptors |
R407 |
T779 |
T778 |
punct |
-,coupled |
R408 |
T780 |
T775 |
pobj |
receptors,of |
R409 |
T781 |
T780 |
punct |
(,receptors |
R410 |
T782 |
T780 |
appos |
GPCRs,receptors |
R411 |
T783 |
T773 |
punct |
),families |
R412 |
T784 |
T773 |
acl |
expressed,families |
R413 |
T785 |
T784 |
prep |
in,expressed |
R414 |
T786 |
T785 |
pobj |
subpopulations,in |
R415 |
T787 |
T786 |
prep |
of,subpopulations |
R416 |
T788 |
T789 |
compound |
taste,cells |
R417 |
T789 |
T787 |
pobj |
cells,of |
R418 |
T790 |
T789 |
compound |
receptor,cells |
R419 |
T791 |
T789 |
punct |
(,cells |
R420 |
T792 |
T789 |
appos |
TRCs,cells |
R421 |
T793 |
T789 |
punct |
),cells |
R422 |
T794 |
T789 |
prep |
of,cells |
R423 |
T795 |
T796 |
det |
the,epithelium |
R424 |
T796 |
T794 |
pobj |
epithelium,of |
R425 |
T797 |
T796 |
amod |
gustatory,epithelium |
R426 |
T798 |
T774 |
aux |
have,implicated |
R427 |
T799 |
T774 |
auxpass |
been,implicated |
R428 |
T800 |
T774 |
prep |
in,implicated |
R429 |
T801 |
T802 |
det |
the,detection |
R430 |
T802 |
T800 |
pobj |
detection,in |
R431 |
T803 |
T802 |
cc |
and,detection |
R432 |
T804 |
T802 |
conj |
transduction,detection |
R433 |
T805 |
T802 |
prep |
of,detection |
R434 |
T806 |
T807 |
amod |
sweet,taste |
R435 |
T807 |
T805 |
pobj |
taste,of |
R436 |
T808 |
T806 |
punct |
", ",sweet |
R437 |
T809 |
T806 |
conj |
bitter,sweet |
R438 |
T810 |
T809 |
cc |
and,bitter |
R439 |
T811 |
T809 |
conj |
umami,bitter |
R440 |
T812 |
T813 |
punct |
(,glutamate |
R441 |
T813 |
T811 |
parataxis |
glutamate,umami |
R442 |
T814 |
T813 |
advmod |
i.e.,glutamate |
R443 |
T815 |
T813 |
punct |
", ",glutamate |
R444 |
T816 |
T813 |
punct |
),glutamate |
R445 |
T817 |
T774 |
punct |
: ,implicated |
R446 |
T818 |
T774 |
dobj |
T1Rs,implicated |
R447 |
T819 |
T818 |
prep |
for,T1Rs |
R448 |
T820 |
T821 |
amod |
sweet,stimuli |
R449 |
T821 |
T819 |
pobj |
stimuli,for |
R450 |
T822 |
T820 |
punct |
-,sweet |
R451 |
T823 |
T820 |
cc |
and,sweet |
R452 |
T824 |
T825 |
amod |
umami,tasting |
R453 |
T825 |
T820 |
conj |
tasting,sweet |
R454 |
T826 |
T825 |
punct |
-,tasting |
R455 |
T827 |
T828 |
punct |
[,1 |
R456 |
T828 |
T818 |
parataxis |
1,T1Rs |
R457 |
T829 |
T830 |
punct |
-,8 |
R458 |
T830 |
T828 |
prep |
8,1 |
R459 |
T831 |
T828 |
punct |
],1 |
R460 |
T832 |
T818 |
punct |
", ",T1Rs |
R461 |
T833 |
T818 |
cc |
and,T1Rs |
R462 |
T834 |
T818 |
conj |
T2Rs,T1Rs |
R463 |
T835 |
T834 |
prep |
for,T2Rs |
R464 |
T836 |
T837 |
amod |
bitter,tasting |
R465 |
T837 |
T839 |
amod |
tasting,compounds |
R466 |
T838 |
T837 |
punct |
-,tasting |
R467 |
T839 |
T835 |
pobj |
compounds,for |
R468 |
T840 |
T841 |
punct |
[,9 |
R469 |
T841 |
T834 |
parataxis |
9,T2Rs |
R470 |
T842 |
T843 |
punct |
-,11 |
R471 |
T843 |
T841 |
prep |
11,9 |
R472 |
T844 |
T841 |
punct |
],9 |
R473 |
T845 |
T774 |
punct |
.,implicated |
R474 |
T847 |
T848 |
det |
The,genes |
R475 |
T848 |
T849 |
nsubjpass |
genes,identified |
R476 |
T850 |
T851 |
dep |
that,encode |
R477 |
T851 |
T848 |
relcl |
encode,genes |
R478 |
T852 |
T851 |
dobj |
T2Rs,encode |
R479 |
T853 |
T848 |
punct |
", ",genes |
R480 |
T854 |
T855 |
det |
the,Tas2rs |
R481 |
T855 |
T848 |
appos |
Tas2rs,genes |
R482 |
T856 |
T849 |
punct |
", ",identified |
R483 |
T857 |
T849 |
auxpass |
were,identified |
R484 |
T858 |
T849 |
advmod |
first,identified |
R485 |
T859 |
T849 |
agent |
by,identified |
R486 |
T860 |
T861 |
compound |
database,mining |
R487 |
T861 |
T859 |
pobj |
mining,by |
R488 |
T862 |
T861 |
prep |
of,mining |
R489 |
T863 |
T864 |
amod |
mammalian,genomes |
R490 |
T864 |
T862 |
pobj |
genomes,of |
R491 |
T865 |
T864 |
prep |
near,genomes |
R492 |
T866 |
T867 |
amod |
chromosomal,markers |
R493 |
T867 |
T865 |
pobj |
markers,near |
R494 |
T868 |
T869 |
advmod |
previously,linked |
R495 |
T869 |
T867 |
acl |
linked,markers |
R496 |
T870 |
T869 |
prep |
to,linked |
R497 |
T871 |
T870 |
pobj |
differences,to |
R498 |
T872 |
T871 |
prep |
in,differences |
R499 |
T873 |
T874 |
amod |
bitter,taste |
R500 |
T874 |
T875 |
compound |
taste,sensitivity |
R501 |
T875 |
T872 |
pobj |
sensitivity,in |
R502 |
T876 |
T877 |
punct |
[,11 |
R503 |
T877 |
T869 |
parataxis |
11,linked |
R504 |
T878 |
T877 |
dep |
9,11 |
R505 |
T879 |
T877 |
punct |
",",11 |
R506 |
T880 |
T881 |
punct |
-,18 |
R507 |
T881 |
T877 |
prep |
18,11 |
R508 |
T882 |
T877 |
punct |
],11 |
R509 |
T883 |
T849 |
punct |
.,identified |
R510 |
T885 |
T886 |
prep |
In,lie |
R511 |
T887 |
T885 |
pobj |
mice,In |
R512 |
T888 |
T886 |
punct |
", ",lie |
R513 |
T889 |
T890 |
det |
the,majority |
R514 |
T890 |
T886 |
nsubj |
majority,lie |
R515 |
T891 |
T890 |
prep |
of,majority |
R516 |
T892 |
T891 |
pobj |
Tas2rs,of |
R517 |
T893 |
T886 |
prep |
within,lie |
R518 |
T894 |
T895 |
det |
a,cluster |
R519 |
T895 |
T893 |
pobj |
cluster,within |
R520 |
T896 |
T895 |
amod |
single,cluster |
R521 |
T897 |
T895 |
prep |
on,cluster |
R522 |
T898 |
T899 |
amod |
distal,chromosome |
R523 |
T899 |
T897 |
pobj |
chromosome,on |
R524 |
T900 |
T899 |
nummod |
6,chromosome |
R525 |
T901 |
T886 |
punct |
.,lie |
R526 |
T903 |
T904 |
compound |
Thirty,three |
R527 |
T904 |
T906 |
nummod |
three,Tas2rs |
R528 |
T905 |
T904 |
punct |
-,three |
R529 |
T906 |
T908 |
nsubjpass |
Tas2rs,identified |
R530 |
T907 |
T906 |
amod |
human,Tas2rs |
R531 |
T909 |
T906 |
punct |
(,Tas2rs |
R532 |
T910 |
T906 |
prep |
including,Tas2rs |
R533 |
T911 |
T912 |
nummod |
8,pseudogenes |
R534 |
T912 |
T910 |
pobj |
pseudogenes,including |
R535 |
T913 |
T906 |
punct |
),Tas2rs |
R536 |
T914 |
T906 |
cc |
and,Tas2rs |
R537 |
T915 |
T916 |
compound |
thirty,six |
R538 |
T916 |
T918 |
nummod |
six,Tas2rs |
R539 |
T917 |
T916 |
punct |
-,six |
R540 |
T918 |
T906 |
conj |
Tas2rs,Tas2rs |
R541 |
T919 |
T918 |
compound |
mouse,Tas2rs |
R542 |
T920 |
T918 |
punct |
(,Tas2rs |
R543 |
T921 |
T918 |
prep |
including,Tas2rs |
R544 |
T922 |
T923 |
nummod |
3,pseudogenes |
R545 |
T923 |
T921 |
pobj |
pseudogenes,including |
R546 |
T924 |
T923 |
prep |
in,pseudogenes |
R547 |
T925 |
T926 |
compound |
C57BL,6J |
R548 |
T926 |
T928 |
compound |
6J,mice |
R549 |
T927 |
T926 |
punct |
/,6J |
R550 |
T928 |
T924 |
pobj |
mice,in |
R551 |
T929 |
T918 |
punct |
),Tas2rs |
R552 |
T930 |
T908 |
aux |
have,identified |
R553 |
T931 |
T908 |
auxpass |
been,identified |
R554 |
T932 |
T933 |
punct |
[,19 |
R555 |
T933 |
T908 |
parataxis |
19,identified |
R556 |
T934 |
T933 |
nummod |
9,19 |
R557 |
T935 |
T933 |
punct |
",",19 |
R558 |
T936 |
T933 |
nummod |
11,19 |
R559 |
T937 |
T933 |
punct |
",",19 |
R560 |
T938 |
T933 |
punct |
],19 |
R561 |
T939 |
T908 |
punct |
", ",identified |
R562 |
T940 |
T908 |
cc |
and,identified |
R563 |
T941 |
T942 |
nsubj |
several,respond |
R564 |
T942 |
T908 |
conj |
respond,identified |
R565 |
T943 |
T941 |
prep |
of,several |
R566 |
T944 |
T943 |
pobj |
these,of |
R567 |
T945 |
T942 |
prep |
to,respond |
R568 |
T946 |
T947 |
amod |
particular,stimuli |
R569 |
T947 |
T945 |
pobj |
stimuli,to |
R570 |
T948 |
T947 |
amod |
bitter,stimuli |
R571 |
T949 |
T942 |
prep |
in,respond |
R572 |
T950 |
T951 |
amod |
heterologous,assays |
R573 |
T951 |
T949 |
pobj |
assays,in |
R574 |
T952 |
T951 |
compound |
expression,assays |
R575 |
T953 |
T954 |
punct |
[,20 |
R576 |
T954 |
T942 |
parataxis |
20,respond |
R577 |
T955 |
T954 |
dep |
10,20 |
R578 |
T956 |
T954 |
punct |
",",20 |
R579 |
T957 |
T958 |
punct |
-,23 |
R580 |
T958 |
T954 |
prep |
23,20 |
R581 |
T959 |
T954 |
punct |
],20 |
R582 |
T960 |
T942 |
punct |
", ",respond |
R583 |
T961 |
T942 |
cc |
or,respond |
R584 |
T962 |
T942 |
conj |
represent,respond |
R585 |
T963 |
T964 |
det |
a,gene |
R586 |
T964 |
T962 |
dobj |
gene,represent |
R587 |
T965 |
T964 |
amod |
strong,gene |
R588 |
T966 |
T964 |
compound |
candidate,gene |
R589 |
T967 |
T964 |
prep |
for,gene |
R590 |
T968 |
T969 |
det |
a,trait |
R591 |
T969 |
T967 |
pobj |
trait,for |
R592 |
T970 |
T969 |
amod |
specific,trait |
R593 |
T971 |
T972 |
amod |
bitter,taste |
R594 |
T972 |
T969 |
nmod |
taste,trait |
R595 |
T973 |
T969 |
amod |
quantitative,trait |
R596 |
T974 |
T975 |
punct |
[,25 |
R597 |
T975 |
T962 |
parataxis |
25,represent |
R598 |
T976 |
T975 |
nummod |
18,25 |
R599 |
T977 |
T975 |
punct |
",",25 |
R600 |
T978 |
T975 |
nummod |
24,25 |
R601 |
T979 |
T975 |
punct |
",",25 |
R602 |
T980 |
T975 |
punct |
],25 |
R603 |
T981 |
T942 |
punct |
.,respond |
R604 |
T983 |
T984 |
amod |
Several,loci |
R605 |
T984 |
T987 |
nsubjpass |
loci,identified |
R606 |
T985 |
T984 |
amod |
quantitative,loci |
R607 |
T986 |
T984 |
compound |
trait,loci |
R608 |
T988 |
T984 |
punct |
(,loci |
R609 |
T989 |
T984 |
appos |
QTL,loci |
R610 |
T990 |
T987 |
punct |
),identified |
R611 |
T991 |
T987 |
aux |
have,identified |
R612 |
T992 |
T987 |
auxpass |
been,identified |
R613 |
T993 |
T994 |
dep |
that,influence |
R614 |
T994 |
T987 |
ccomp |
influence,identified |
R615 |
T995 |
T996 |
nummod |
two,bottle |
R616 |
T996 |
T998 |
compound |
bottle,intake |
R617 |
T997 |
T996 |
punct |
-,bottle |
R618 |
T998 |
T994 |
dobj |
intake,influence |
R619 |
T999 |
T998 |
prep |
of,intake |
R620 |
T1000 |
T1001 |
amod |
bitter,stimuli |
R621 |
T1001 |
T999 |
pobj |
stimuli,of |
R622 |
T1002 |
T998 |
prep |
in,intake |
R623 |
T1003 |
T1004 |
det |
the,mouse |
R624 |
T1004 |
T1002 |
pobj |
mouse,in |
R625 |
T1005 |
T987 |
punct |
", ",identified |
R626 |
T1006 |
T987 |
prep |
including,identified |
R627 |
T1007 |
T1006 |
pobj |
loci,including |
R628 |
T1008 |
T1007 |
prep |
for,loci |
R629 |
T1009 |
T1010 |
nmod |
quinine,sensitivity |
R630 |
T1010 |
T1008 |
pobj |
sensitivity,for |
R631 |
T1011 |
T1009 |
punct |
(,quinine |
R632 |
T1012 |
T1009 |
appos |
Qui,quinine |
R633 |
T1013 |
T1009 |
punct |
),quinine |
R634 |
T1014 |
T1015 |
punct |
[,26 |
R635 |
T1015 |
T1009 |
parataxis |
26,quinine |
R636 |
T1016 |
T1015 |
nummod |
12,26 |
R637 |
T1017 |
T1015 |
punct |
",",26 |
R638 |
T1018 |
T1015 |
nummod |
16,26 |
R639 |
T1019 |
T1015 |
punct |
",",26 |
R640 |
T1020 |
T1015 |
punct |
],26 |
R641 |
T1021 |
T1009 |
punct |
", ",quinine |
R642 |
T1022 |
T1009 |
conj |
cyclohexamide,quinine |
R643 |
T1023 |
T1022 |
punct |
(,cyclohexamide |
R644 |
T1024 |
T1022 |
appos |
Cyx,cyclohexamide |
R645 |
T1025 |
T1022 |
punct |
),cyclohexamide |
R646 |
T1026 |
T1027 |
punct |
[,13 |
R647 |
T1027 |
T1022 |
parataxis |
13,cyclohexamide |
R648 |
T1028 |
T1027 |
punct |
],13 |
R649 |
T1029 |
T1022 |
cc |
and,cyclohexamide |
R650 |
T1030 |
T1031 |
compound |
sucrose,octaacetate |
R651 |
T1031 |
T1022 |
conj |
octaacetate,cyclohexamide |
R652 |
T1032 |
T1031 |
punct |
(,octaacetate |
R653 |
T1033 |
T1031 |
appos |
Soa,octaacetate |
R654 |
T1034 |
T1031 |
punct |
),octaacetate |
R655 |
T1035 |
T1036 |
punct |
[,17 |
R656 |
T1036 |
T1031 |
parataxis |
17,octaacetate |
R657 |
T1037 |
T1036 |
nummod |
14,17 |
R658 |
T1038 |
T1036 |
punct |
",",17 |
R659 |
T1039 |
T1036 |
nummod |
15,17 |
R660 |
T1040 |
T1036 |
punct |
",",17 |
R661 |
T1041 |
T1036 |
punct |
],17 |
R662 |
T1042 |
T987 |
punct |
.,identified |
R663 |
T1044 |
T1045 |
nsubj |
Each,map |
R664 |
T1046 |
T1044 |
prep |
of,Each |
R665 |
T1047 |
T1048 |
det |
these,QTL |
R666 |
T1048 |
T1046 |
pobj |
QTL,of |
R667 |
T1049 |
T1045 |
prep |
to,map |
R668 |
T1050 |
T1051 |
nmod |
mouse,chromosome |
R669 |
T1051 |
T1049 |
pobj |
chromosome,to |
R670 |
T1052 |
T1051 |
amod |
distal,chromosome |
R671 |
T1053 |
T1051 |
nummod |
6,chromosome |
R672 |
T1054 |
T1045 |
cc |
and,map |
R673 |
T1055 |
T1056 |
auxpass |
are,linked |
R674 |
T1056 |
T1045 |
conj |
linked,map |
R675 |
T1057 |
T1056 |
prep |
to,linked |
R676 |
T1058 |
T1059 |
det |
the,D6Mit13 |
R677 |
T1059 |
T1057 |
pobj |
D6Mit13,to |
R678 |
T1060 |
T1059 |
compound |
marker,D6Mit13 |
R679 |
T1061 |
T1059 |
punct |
", ",D6Mit13 |
R680 |
T1062 |
T1063 |
dep |
which,lies |
R681 |
T1063 |
T1059 |
relcl |
lies,D6Mit13 |
R682 |
T1064 |
T1063 |
prep |
within,lies |
R683 |
T1065 |
T1066 |
det |
a,cluster |
R684 |
T1066 |
T1064 |
pobj |
cluster,within |
R685 |
T1067 |
T1066 |
prep |
of,cluster |
R686 |
T1068 |
T1069 |
nummod |
24,Tas2rs |
R687 |
T1069 |
T1067 |
pobj |
Tas2rs,of |
R688 |
T1070 |
T1069 |
amod |
intact,Tas2rs |
R689 |
T1071 |
T1063 |
prep |
in,lies |
R690 |
T1072 |
T1073 |
det |
the,genome |
R691 |
T1073 |
T1071 |
pobj |
genome,in |
R692 |
T1074 |
T1073 |
nmod |
C57BL,genome |
R693 |
T1075 |
T1074 |
punct |
/,C57BL |
R694 |
T1076 |
T1074 |
nummod |
6,C57BL |
R695 |
T1077 |
T1078 |
punct |
(,28 |
R696 |
T1078 |
T1063 |
parataxis |
28,lies |
R697 |
T1079 |
T1078 |
advmod |
e.g.,28 |
R698 |
T1080 |
T1078 |
punct |
", ",28 |
R699 |
T1081 |
T1078 |
punct |
[,28 |
R700 |
T1082 |
T1078 |
nummod |
16,28 |
R701 |
T1083 |
T1078 |
punct |
",",28 |
R702 |
T1084 |
T1078 |
nummod |
27,28 |
R703 |
T1085 |
T1078 |
punct |
",",28 |
R704 |
T1086 |
T1078 |
punct |
],28 |
R705 |
T1087 |
T1078 |
punct |
),28 |
R706 |
T1088 |
T1045 |
punct |
.,map |
R707 |
T1090 |
T1091 |
advmod |
However,remains |
R708 |
T1092 |
T1091 |
punct |
", ",remains |
R709 |
T1093 |
T1094 |
det |
the,interpretation |
R710 |
T1094 |
T1091 |
nsubj |
interpretation,remains |
R711 |
T1095 |
T1094 |
prep |
of,interpretation |
R712 |
T1096 |
T1097 |
det |
these,studies |
R713 |
T1097 |
T1095 |
pobj |
studies,of |
R714 |
T1098 |
T1091 |
acomp |
problematic,remains |
R715 |
T1099 |
T1091 |
prep |
for,remains |
R716 |
T1100 |
T1101 |
nummod |
two,reasons |
R717 |
T1101 |
T1099 |
pobj |
reasons,for |
R718 |
T1102 |
T1091 |
punct |
.,remains |
R719 |
T1104 |
T1105 |
advmod |
First,permit |
R720 |
T1106 |
T1105 |
punct |
", ",permit |
R721 |
T1107 |
T1108 |
det |
the,density |
R722 |
T1108 |
T1105 |
nsubj |
density,permit |
R723 |
T1109 |
T1108 |
prep |
of,density |
R724 |
T1110 |
T1111 |
amod |
chromosomal,markers |
R725 |
T1111 |
T1109 |
pobj |
markers,of |
R726 |
T1112 |
T1108 |
cc |
and,density |
R727 |
T1113 |
T1108 |
conj |
number,density |
R728 |
T1114 |
T1113 |
prep |
of,number |
R729 |
T1115 |
T1116 |
amod |
recombinant,inbred |
R730 |
T1116 |
T1117 |
amod |
inbred,RI |
R731 |
T1117 |
T1119 |
amod |
RI,strains |
R732 |
T1118 |
T1117 |
punct |
(,RI |
R733 |
T1119 |
T1114 |
pobj |
strains,of |
R734 |
T1120 |
T1119 |
punct |
),strains |
R735 |
T1121 |
T1113 |
acl |
used,number |
R736 |
T1122 |
T1121 |
prep |
in,used |
R737 |
T1123 |
T1124 |
det |
these,studies |
R738 |
T1124 |
T1122 |
pobj |
studies,in |
R739 |
T1125 |
T1124 |
amod |
earlier,studies |
R740 |
T1126 |
T1105 |
aux |
did,permit |
R741 |
T1127 |
T1105 |
neg |
not,permit |
R742 |
T1128 |
T1129 |
det |
the,definition |
R743 |
T1129 |
T1105 |
dobj |
definition,permit |
R744 |
T1130 |
T1129 |
amod |
physical,definition |
R745 |
T1131 |
T1129 |
prep |
of,definition |
R746 |
T1132 |
T1133 |
det |
the,intervals |
R747 |
T1133 |
T1131 |
pobj |
intervals,of |
R748 |
T1134 |
T1133 |
acl |
containing,intervals |
R749 |
T1135 |
T1136 |
det |
each,QTL |
R750 |
T1136 |
T1134 |
dobj |
QTL,containing |
R751 |
T1137 |
T1105 |
punct |
.,permit |
R752 |
T1139 |
T1140 |
advmod |
Second,relied |
R753 |
T1141 |
T1140 |
punct |
", ",relied |
R754 |
T1142 |
T1143 |
det |
these,attempts |
R755 |
T1143 |
T1140 |
nsubj |
attempts,relied |
R756 |
T1144 |
T1143 |
amod |
previous,attempts |
R757 |
T1145 |
T1146 |
aux |
to,map |
R758 |
T1146 |
T1143 |
acl |
map,attempts |
R759 |
T1147 |
T1148 |
amod |
bitter,taste |
R760 |
T1148 |
T1149 |
compound |
taste,QTLs |
R761 |
T1149 |
T1146 |
dobj |
QTLs,map |
R762 |
T1150 |
T1140 |
prep |
on,relied |
R763 |
T1151 |
T1152 |
amod |
behavioral,assays |
R764 |
T1152 |
T1150 |
pobj |
assays,on |
R765 |
T1153 |
T1154 |
dep |
that,measured |
R766 |
T1154 |
T1152 |
relcl |
measured,assays |
R767 |
T1155 |
T1154 |
dobj |
consumption,measured |
R768 |
T1156 |
T1140 |
punct |
", ",relied |
R769 |
T1157 |
T1140 |
cc |
and,relied |
R770 |
T1158 |
T1140 |
conj |
were,relied |
R771 |
T1159 |
T1158 |
advmod |
thus,were |
R772 |
T1160 |
T1158 |
acomp |
susceptible,were |
R773 |
T1161 |
T1160 |
prep |
to,susceptible |
R774 |
T1162 |
T1161 |
pobj |
contributions,to |
R775 |
T1163 |
T1162 |
prep |
of,contributions |
R776 |
T1164 |
T1165 |
amod |
post-ingestive,effects |
R777 |
T1165 |
T1163 |
pobj |
effects,of |
R778 |
T1166 |
T1167 |
amod |
such,as |
R779 |
T1167 |
T1165 |
prep |
as,effects |
R780 |
T1168 |
T1167 |
pobj |
toxicity,as |
R781 |
T1169 |
T1140 |
punct |
.,relied |
R782 |
T1171 |
T1172 |
mark |
As,shown |
R783 |
T1172 |
T1175 |
advcl |
shown,confound |
R784 |
T1173 |
T1172 |
nsubj |
we,shown |
R785 |
T1174 |
T1172 |
aux |
have,shown |
R786 |
T1176 |
T1172 |
advmod |
previously,shown |
R787 |
T1177 |
T1175 |
punct |
", ",confound |
R788 |
T1178 |
T1179 |
amod |
such,effects |
R789 |
T1179 |
T1175 |
nsubj |
effects,confound |
R790 |
T1180 |
T1175 |
aux |
can,confound |
R791 |
T1181 |
T1182 |
det |
the,quantification |
R792 |
T1182 |
T1175 |
dobj |
quantification,confound |
R793 |
T1183 |
T1182 |
prep |
of,quantification |
R794 |
T1184 |
T1185 |
amod |
bitter,taste |
R795 |
T1185 |
T1186 |
compound |
taste,behaviors |
R796 |
T1186 |
T1183 |
pobj |
behaviors,of |
R797 |
T1187 |
T1188 |
punct |
[,29 |
R798 |
T1188 |
T1175 |
parataxis |
29,confound |
R799 |
T1189 |
T1188 |
punct |
],29 |
R800 |
T1190 |
T1175 |
punct |
.,confound |
R801 |
T1192 |
T1193 |
advmod |
Therefore,remain |
R802 |
T1194 |
T1193 |
punct |
", ",remain |
R803 |
T1195 |
T1196 |
det |
the,relevance |
R804 |
T1196 |
T1193 |
nsubj |
relevance,remain |
R805 |
T1197 |
T1196 |
cc |
and,relevance |
R806 |
T1198 |
T1197 |
punct |
/,and |
R807 |
T1199 |
T1197 |
cc |
or,and |
R808 |
T1200 |
T1196 |
conj |
contribution,relevance |
R809 |
T1201 |
T1196 |
prep |
of,relevance |
R810 |
T1202 |
T1203 |
det |
the,QTLs |
R811 |
T1203 |
T1201 |
pobj |
QTLs,of |
R812 |
T1204 |
T1203 |
amod |
aforementioned,QTLs |
R813 |
T1205 |
T1196 |
prep |
to,relevance |
R814 |
T1206 |
T1207 |
amod |
bitter,taste |
R815 |
T1207 |
T1205 |
pobj |
taste,to |
R816 |
T1208 |
T1193 |
acomp |
unclear,remain |
R817 |
T1209 |
T1193 |
punct |
.,remain |
R818 |
T1211 |
T1212 |
advmod |
Furthermore,suggested |
R819 |
T1213 |
T1212 |
punct |
", ",suggested |
R820 |
T1214 |
T1215 |
det |
a,number |
R821 |
T1215 |
T1212 |
nsubj |
number,suggested |
R822 |
T1216 |
T1215 |
prep |
of,number |
R823 |
T1217 |
T1218 |
amod |
physiological,studies |
R824 |
T1218 |
T1216 |
pobj |
studies,of |
R825 |
T1219 |
T1212 |
aux |
have,suggested |
R826 |
T1220 |
T1221 |
mark |
that,stimulate |
R827 |
T1221 |
T1212 |
ccomp |
stimulate,suggested |
R828 |
T1222 |
T1223 |
det |
the,transduction |
R829 |
T1223 |
T1221 |
nsubj |
transduction,stimulate |
R830 |
T1224 |
T1223 |
prep |
of,transduction |
R831 |
T1225 |
T1226 |
det |
some,compounds |
R832 |
T1226 |
T1224 |
pobj |
compounds,of |
R833 |
T1227 |
T1226 |
amod |
amphiphilic,compounds |
R834 |
T1228 |
T1226 |
amod |
bitter,compounds |
R835 |
T1229 |
T1226 |
punct |
", ",compounds |
R836 |
T1230 |
T1231 |
amod |
such,as |
R837 |
T1231 |
T1226 |
prep |
as,compounds |
R838 |
T1232 |
T1231 |
pobj |
quinine,as |
R839 |
T1233 |
T1232 |
cc |
and,quinine |
R840 |
T1234 |
T1235 |
compound |
denatonium,benzoate |
R841 |
T1235 |
T1232 |
conj |
benzoate,quinine |
R842 |
T1236 |
T1221 |
punct |
", ",stimulate |
R843 |
T1237 |
T1221 |
aux |
may,stimulate |
R844 |
T1238 |
T1239 |
compound |
taste,receptor |
R845 |
T1239 |
T1240 |
compound |
receptor,cells |
R846 |
T1240 |
T1221 |
dobj |
cells,stimulate |
R847 |
T1241 |
T1221 |
advmod |
independently,stimulate |
R848 |
T1242 |
T1241 |
prep |
of,independently |
R849 |
T1243 |
T1242 |
pobj |
GPCRs,of |
R850 |
T1244 |
T1245 |
punct |
(,30 |
R851 |
T1245 |
T1221 |
parataxis |
30,stimulate |
R852 |
T1246 |
T1245 |
advmod |
e.g.,30 |
R853 |
T1247 |
T1245 |
punct |
[,30 |
R854 |
T1248 |
T1245 |
punct |
],30 |
R855 |
T1249 |
T1245 |
punct |
),30 |
R856 |
T1250 |
T1212 |
punct |
.,suggested |
R857 |
T1252 |
T1253 |
nsubj |
Quinine,activate |
R858 |
T1253 |
T1256 |
ccomp |
activate,inhibits |
R859 |
T1254 |
T1253 |
aux |
may,activate |
R860 |
T1255 |
T1253 |
advmod |
directly,activate |
R861 |
T1257 |
T1258 |
compound |
G,proteins |
R862 |
T1258 |
T1253 |
dobj |
proteins,activate |
R863 |
T1259 |
T1253 |
punct |
", ",activate |
R864 |
T1260 |
T1253 |
cc |
and,activate |
R865 |
T1261 |
T1262 |
preconj |
both,quinine |
R866 |
T1262 |
T1263 |
nsubj |
quinine,block |
R867 |
T1263 |
T1253 |
conj |
block,activate |
R868 |
T1264 |
T1262 |
cc |
and,quinine |
R869 |
T1265 |
T1262 |
conj |
denatonium,quinine |
R870 |
T1266 |
T1263 |
aux |
can,block |
R871 |
T1267 |
T1268 |
nmod |
K,channels |
R872 |
T1268 |
T1263 |
dobj |
channels,block |
R873 |
T1269 |
T1267 |
punct |
+,K |
R874 |
T1270 |
T1271 |
punct |
[,31 |
R875 |
T1271 |
T1263 |
parataxis |
31,block |
R876 |
T1272 |
T1273 |
punct |
-,36 |
R877 |
T1273 |
T1271 |
prep |
36,31 |
R878 |
T1274 |
T1271 |
punct |
],31 |
R879 |
T1275 |
T1256 |
punct |
;,inhibits |
R880 |
T1276 |
T1256 |
nsubj |
caffeine,inhibits |
R881 |
T1277 |
T1276 |
punct |
", ",caffeine |
R882 |
T1278 |
T1279 |
det |
another,substance |
R883 |
T1279 |
T1276 |
appos |
substance,caffeine |
R884 |
T1280 |
T1281 |
amod |
bitter,tasting |
R885 |
T1281 |
T1279 |
amod |
tasting,substance |
R886 |
T1282 |
T1281 |
punct |
-,tasting |
R887 |
T1283 |
T1256 |
punct |
", ",inhibits |
R888 |
T1284 |
T1256 |
advmod |
directly,inhibits |
R889 |
T1285 |
T1286 |
amod |
intracellular,phosphodiesterase |
R890 |
T1286 |
T1256 |
dobj |
phosphodiesterase,inhibits |
R891 |
T1287 |
T1288 |
punct |
[,33 |
R892 |
T1288 |
T1256 |
parataxis |
33,inhibits |
R893 |
T1289 |
T1288 |
punct |
],33 |
R894 |
T1290 |
T1256 |
punct |
.,inhibits |
R895 |
T1292 |
T1293 |
advmod |
However,are |
R896 |
T1294 |
T1293 |
punct |
", ",are |
R897 |
T1295 |
T1296 |
det |
the,contributions |
R898 |
T1296 |
T1293 |
nsubj |
contributions,are |
R899 |
T1297 |
T1296 |
amod |
relative,contributions |
R900 |
T1298 |
T1296 |
prep |
of,contributions |
R901 |
T1299 |
T1300 |
npadvmod |
T2R,dependent |
R902 |
T1300 |
T1302 |
amod |
dependent,mechanisms |
R903 |
T1301 |
T1300 |
punct |
-,dependent |
R904 |
T1302 |
T1298 |
pobj |
mechanisms,of |
R905 |
T1303 |
T1300 |
cc |
and,dependent |
R906 |
T1304 |
T1305 |
npadvmod |
T2R,independent |
R907 |
T1305 |
T1300 |
conj |
independent,dependent |
R908 |
T1306 |
T1305 |
punct |
-,independent |
R909 |
T1307 |
T1296 |
prep |
to,contributions |
R910 |
T1308 |
T1309 |
det |
the,detection |
R911 |
T1309 |
T1307 |
pobj |
detection,to |
R912 |
T1310 |
T1309 |
prep |
of,detection |
R913 |
T1311 |
T1312 |
det |
these,stimuli |
R914 |
T1312 |
T1310 |
pobj |
stimuli,of |
R915 |
T1313 |
T1312 |
amod |
bitter,stimuli |
R916 |
T1314 |
T1293 |
acomp |
unknown,are |
R917 |
T1315 |
T1293 |
punct |
.,are |
R918 |
T1317 |
T1318 |
advmod |
Here,use |
R919 |
T1319 |
T1318 |
nsubj |
we,use |
R920 |
T1320 |
T1321 |
det |
a,test |
R921 |
T1321 |
T1318 |
dobj |
test,use |
R922 |
T1322 |
T1323 |
npadvmod |
taste,salient |
R923 |
T1323 |
T1321 |
amod |
salient,test |
R924 |
T1324 |
T1323 |
punct |
-,salient |
R925 |
T1325 |
T1326 |
amod |
brief,access |
R926 |
T1326 |
T1321 |
compound |
access,test |
R927 |
T1327 |
T1326 |
punct |
-,access |
R928 |
T1328 |
T1321 |
compound |
lick,test |
R929 |
T1329 |
T1330 |
punct |
[,37 |
R930 |
T1330 |
T1321 |
parataxis |
37,test |
R931 |
T1331 |
T1330 |
nummod |
29,37 |
R932 |
T1332 |
T1330 |
punct |
",",37 |
R933 |
T1333 |
T1330 |
punct |
],37 |
R934 |
T1334 |
T1335 |
aux |
to,measure |
R935 |
T1335 |
T1318 |
advcl |
measure,use |
R936 |
T1336 |
T1337 |
compound |
taste,sensitivities |
R937 |
T1337 |
T1335 |
dobj |
sensitivities,measure |
R938 |
T1338 |
T1337 |
prep |
in,sensitivities |
R939 |
T1339 |
T1340 |
nmod |
C57BL,6J |
R940 |
T1340 |
T1342 |
nmod |
6J,mice |
R941 |
T1341 |
T1340 |
punct |
/,6J |
R942 |
T1342 |
T1338 |
pobj |
mice,in |
R943 |
T1343 |
T1340 |
punct |
(,6J |
R944 |
T1344 |
T1340 |
appos |
B6,6J |
R945 |
T1345 |
T1340 |
punct |
),6J |
R946 |
T1346 |
T1340 |
punct |
", ",6J |
R947 |
T1347 |
T1348 |
compound |
DBA,2J |
R948 |
T1348 |
T1340 |
conj |
2J,6J |
R949 |
T1349 |
T1348 |
punct |
/,2J |
R950 |
T1350 |
T1348 |
punct |
(,2J |
R951 |
T1351 |
T1348 |
appos |
D2,2J |
R952 |
T1352 |
T1348 |
punct |
),2J |
R953 |
T1353 |
T1348 |
cc |
and,2J |
R954 |
T1354 |
T1355 |
compound |
BXD,Ty |
R955 |
T1355 |
T1348 |
conj |
Ty,2J |
R956 |
T1356 |
T1355 |
punct |
/,Ty |
R957 |
T1357 |
T1355 |
punct |
(,Ty |
R958 |
T1358 |
T1355 |
appos |
BXD,Ty |
R959 |
T1359 |
T1355 |
punct |
),Ty |
R960 |
T1360 |
T1361 |
amod |
recombinant,inbred |
R961 |
T1361 |
T1342 |
amod |
inbred,mice |
R962 |
T1362 |
T1363 |
punct |
(,RI |
R963 |
T1363 |
T1361 |
parataxis |
RI,inbred |
R964 |
T1364 |
T1363 |
punct |
),RI |
R965 |
T1365 |
T1337 |
prep |
to,sensitivities |
R966 |
T1366 |
T1367 |
nummod |
two,stimuli |
R967 |
T1367 |
T1365 |
pobj |
stimuli,to |
R968 |
T1368 |
T1367 |
amod |
bitter,stimuli |
R969 |
T1369 |
T1367 |
punct |
", ",stimuli |
R970 |
T1370 |
T1371 |
compound |
quinine,hydrochloride |
R971 |
T1371 |
T1367 |
appos |
hydrochloride,stimuli |
R972 |
T1372 |
T1371 |
punct |
(,hydrochloride |
R973 |
T1373 |
T1371 |
appos |
QHCl,hydrochloride |
R974 |
T1374 |
T1371 |
punct |
),hydrochloride |
R975 |
T1375 |
T1371 |
cc |
and,hydrochloride |
R976 |
T1376 |
T1377 |
compound |
denatonium,benzoate |
R977 |
T1377 |
T1371 |
conj |
benzoate,hydrochloride |
R978 |
T1378 |
T1377 |
punct |
(,benzoate |
R979 |
T1379 |
T1377 |
appos |
DB,benzoate |
R980 |
T1380 |
T1318 |
punct |
),use |
R981 |
T1381 |
T1318 |
punct |
.,use |
R982 |
T1383 |
T1384 |
advcl |
Using,mapped |
R983 |
T1385 |
T1386 |
nummod |
17,lines |
R984 |
T1386 |
T1383 |
dobj |
lines,Using |
R985 |
T1387 |
T1386 |
compound |
BXD,lines |
R986 |
T1388 |
T1389 |
dep |
that,genotyped |
R987 |
T1389 |
T1386 |
relcl |
genotyped,lines |
R988 |
T1390 |
T1389 |
auxpass |
were,genotyped |
R989 |
T1391 |
T1389 |
prep |
at,genotyped |
R990 |
T1392 |
T1393 |
nummod |
762,markers |
R991 |
T1393 |
T1391 |
pobj |
markers,at |
R992 |
T1394 |
T1393 |
amod |
informative,markers |
R993 |
T1395 |
T1393 |
amod |
chromosomal,markers |
R994 |
T1396 |
T1384 |
punct |
", ",mapped |
R995 |
T1397 |
T1384 |
nsubj |
we,mapped |
R996 |
T1398 |
T1399 |
det |
a,QTL |
R997 |
T1399 |
T1384 |
dobj |
QTL,mapped |
R998 |
T1400 |
T1399 |
amod |
major,QTL |
R999 |
T1401 |
T1399 |
prep |
for,QTL |
R1000 |
T1402 |
T1403 |
compound |
QHCl,taste |
R1001 |
T1403 |
T1401 |
pobj |
taste,for |
R1002 |
T1404 |
T1384 |
prep |
to,mapped |
R1003 |
T1405 |
T1406 |
det |
a,interval |
R1004 |
T1406 |
T1404 |
pobj |
interval,to |
R1005 |
T1407 |
T1408 |
punct |
~,5 |
R1006 |
T1408 |
T1409 |
nummod |
5,Mb |
R1007 |
T1409 |
T1406 |
compound |
Mb,interval |
R1008 |
T1410 |
T1406 |
prep |
on,interval |
R1009 |
T1411 |
T1412 |
amod |
distal,chromosome |
R1010 |
T1412 |
T1410 |
pobj |
chromosome,on |
R1011 |
T1413 |
T1412 |
nummod |
6,chromosome |
R1012 |
T1414 |
T1415 |
dep |
that,contains |
R1013 |
T1415 |
T1406 |
relcl |
contains,interval |
R1014 |
T1416 |
T1417 |
det |
all,24 |
R1015 |
T1417 |
T1415 |
dobj |
24,contains |
R1016 |
T1418 |
T1417 |
prep |
of,24 |
R1017 |
T1419 |
T1420 |
det |
the,genes |
R1018 |
T1420 |
T1418 |
pobj |
genes,of |
R1019 |
T1421 |
T1420 |
compound |
Tas2r,genes |
R1020 |
T1422 |
T1420 |
prep |
in,genes |
R1021 |
T1423 |
T1424 |
det |
the,cluster |
R1022 |
T1424 |
T1422 |
pobj |
cluster,in |
R1023 |
T1425 |
T1424 |
amod |
distal,cluster |
R1024 |
T1426 |
T1384 |
punct |
.,mapped |
R1025 |
T1428 |
T1429 |
nsubj |
We,analyzed |
R1026 |
T1430 |
T1431 |
det |
the,sequence |
R1027 |
T1431 |
T1429 |
dobj |
sequence,analyzed |
R1028 |
T1432 |
T1431 |
prep |
of,sequence |
R1029 |
T1433 |
T1434 |
det |
each,allele |
R1030 |
T1434 |
T1432 |
pobj |
allele,of |
R1031 |
T1435 |
T1434 |
compound |
Tas2r,allele |
R1032 |
T1436 |
T1429 |
prep |
in,analyzed |
R1033 |
T1437 |
T1438 |
det |
the,strains |
R1034 |
T1438 |
T1436 |
pobj |
strains,in |
R1035 |
T1439 |
T1438 |
amod |
parental,strains |
R1036 |
T1440 |
T1438 |
punct |
(,strains |
R1037 |
T1441 |
T1438 |
appos |
B6,strains |
R1038 |
T1442 |
T1441 |
cc |
and,B6 |
R1039 |
T1443 |
T1441 |
conj |
D2,B6 |
R1040 |
T1444 |
T1438 |
punct |
),strains |
R1041 |
T1445 |
T1438 |
cc |
and,strains |
R1042 |
T1446 |
T1447 |
nummod |
29,lines |
R1043 |
T1447 |
T1438 |
conj |
lines,strains |
R1044 |
T1448 |
T1447 |
amod |
RI,lines |
R1045 |
T1449 |
T1429 |
punct |
.,analyzed |
R1046 |
T1451 |
T1452 |
det |
This,analysis |
R1047 |
T1452 |
T1453 |
nsubj |
analysis,revealed |
R1048 |
T1454 |
T1455 |
mark |
that,are |
R1049 |
T1455 |
T1453 |
advcl |
are,revealed |
R1050 |
T1456 |
T1457 |
det |
all,genes |
R1051 |
T1457 |
T1455 |
nsubj |
genes,are |
R1052 |
T1458 |
T1457 |
nummod |
24,genes |
R1053 |
T1459 |
T1455 |
acomp |
polymorphic,are |
R1054 |
T1460 |
T1459 |
prep |
between,polymorphic |
R1055 |
T1461 |
T1462 |
det |
the,strains |
R1056 |
T1462 |
T1460 |
pobj |
strains,between |
R1057 |
T1463 |
T1462 |
nummod |
two,strains |
R1058 |
T1464 |
T1455 |
punct |
", ",are |
R1059 |
T1465 |
T1455 |
cc |
and,are |
R1060 |
T1466 |
T1467 |
mark |
that,comprise |
R1061 |
T1467 |
T1455 |
conj |
comprise,are |
R1062 |
T1468 |
T1469 |
det |
these,Tas2rs |
R1063 |
T1469 |
T1467 |
nsubj |
Tas2rs,comprise |
R1064 |
T1470 |
T1469 |
nummod |
24,Tas2rs |
R1065 |
T1471 |
T1472 |
det |
a,haplotype |
R1066 |
T1472 |
T1467 |
dobj |
haplotype,comprise |
R1067 |
T1473 |
T1472 |
amod |
single,haplotype |
R1068 |
T1474 |
T1475 |
dep |
that,correlates |
R1069 |
T1475 |
T1472 |
relcl |
correlates,haplotype |
R1070 |
T1476 |
T1475 |
prep |
with,correlates |
R1071 |
T1477 |
T1478 |
compound |
QHCl,taste |
R1072 |
T1478 |
T1479 |
compound |
taste,sensitivity |
R1073 |
T1479 |
T1476 |
pobj |
sensitivity,with |
R1074 |
T1480 |
T1453 |
punct |
.,revealed |