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3 The QHCl QTL is linked to a single marker on chromosome 6. (A) As shown in the interval map for chromosome 6, the trait value (lick ratio for 1 mM QHCl) correlates strongly across BXD RI strains with the polymorphic marker D6Mit13 (bold). The dashed line indicates genome-wide significance. (B) The QHCl QTL (which lies between unlinked markers D6Mit61 and D6Mit 374) contains a cluster of putative bitter taste receptor genes, the Tas2rs (gray box). Physical positions of the polymorphic markers are given in Mb, and are based on the May, 2004 build of the B6 mouse genome. The physical position of D6Mit194 (*) is tentative."}

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