Id |
Subject |
Object |
Predicate |
Lexical cue |
T264 |
11-15 |
NN |
denotes |
chow |
T265 |
5-10 |
NN |
denotes |
mouse |
T266 |
15-17 |
, |
denotes |
, |
T267 |
17-21 |
VBP |
denotes |
have |
T268 |
22-34 |
NN |
denotes |
inflammation |
T269 |
35-37 |
IN |
denotes |
of |
T270 |
38-41 |
DT |
denotes |
the |
T271 |
48-57 |
NN |
denotes |
intestine |
T272 |
42-47 |
JJ |
denotes |
small |
T273 |
57-59 |
, |
denotes |
, |
T274 |
59-62 |
CC |
denotes |
and |
T275 |
63-66 |
VBP |
denotes |
are |
T276 |
67-72 |
IN |
denotes |
about |
T277 |
73-75 |
CD |
denotes |
30 |
T278 |
75-76 |
NN |
denotes |
% |
T279 |
77-84 |
JJR |
denotes |
smaller |
T280 |
85-89 |
IN |
denotes |
than |
T281 |
90-94 |
JJ |
denotes |
wild |
T282 |
95-99 |
NN |
denotes |
type |
T283 |
100-111 |
NNS |
denotes |
littermates |
T284 |
111-112 |
. |
denotes |
. |
T285 |
112-197 |
sentence |
denotes |
In this work potential modifier loci of the CF intestinal phenotype were identified. |
T286 |
113-115 |
IN |
denotes |
In |
T287 |
186-196 |
VBN |
denotes |
identified |
T288 |
116-120 |
DT |
denotes |
this |
T289 |
121-125 |
NN |
denotes |
work |
T290 |
126-135 |
NN |
denotes |
potential |
T291 |
145-149 |
NNS |
denotes |
loci |
T292 |
136-144 |
NN |
denotes |
modifier |
T293 |
150-152 |
IN |
denotes |
of |
T294 |
153-156 |
DT |
denotes |
the |
T295 |
171-180 |
NN |
denotes |
phenotype |
T296 |
157-159 |
NN |
denotes |
CF |
T297 |
160-170 |
JJ |
denotes |
intestinal |
T298 |
181-185 |
VBD |
denotes |
were |
T299 |
196-197 |
. |
denotes |
. |
T300 |
197-206 |
sentence |
denotes |
Results |
T301 |
199-206 |
NNS |
denotes |
Results |
T302 |
206-386 |
sentence |
denotes |
CF mice on a mixed genetic background (95% C57Bl/6 and 5% 129Sv) were compared to CF mice congenic on the C57Bl/6 background for several parameters of the intestinal CF phenotype. |
T303 |
207-209 |
NN |
denotes |
CF |
T304 |
210-214 |
NNS |
denotes |
mice |
T305 |
277-285 |
VBN |
denotes |
compared |
T306 |
215-217 |
IN |
denotes |
on |
T307 |
218-219 |
DT |
denotes |
a |
T308 |
234-244 |
NN |
denotes |
background |
T309 |
220-225 |
JJ |
denotes |
mixed |
T310 |
226-233 |
JJ |
denotes |
genetic |
T311 |
245-246 |
-LRB- |
denotes |
( |
T312 |
250-255 |
NN |
denotes |
C57Bl |
T313 |
246-248 |
CD |
denotes |
95 |
T314 |
248-249 |
NN |
denotes |
% |
T315 |
255-256 |
HYPH |
denotes |
/ |
T316 |
256-257 |
CD |
denotes |
6 |
T317 |
258-261 |
CC |
denotes |
and |
T318 |
262-263 |
CD |
denotes |
5 |
T319 |
265-270 |
NN |
denotes |
129Sv |
T320 |
263-264 |
NN |
denotes |
% |
T321 |
270-271 |
-RRB- |
denotes |
) |
T322 |
272-276 |
VBD |
denotes |
were |
T323 |
286-288 |
IN |
denotes |
to |
T324 |
289-291 |
NN |
denotes |
CF |
T325 |
292-296 |
NNS |
denotes |
mice |
T326 |
297-305 |
JJ |
denotes |
congenic |
T327 |
306-308 |
IN |
denotes |
on |
T328 |
309-312 |
DT |
denotes |
the |
T329 |
321-331 |
NN |
denotes |
background |
T330 |
313-318 |
NN |
denotes |
C57Bl |
T331 |
318-319 |
HYPH |
denotes |
/ |
T332 |
319-320 |
CD |
denotes |
6 |
T333 |
332-335 |
IN |
denotes |
for |
T334 |
336-343 |
JJ |
denotes |
several |
T335 |
344-354 |
NNS |
denotes |
parameters |
T336 |
355-357 |
IN |
denotes |
of |
T337 |
358-361 |
DT |
denotes |
the |
T338 |
376-385 |
NN |
denotes |
phenotype |
T339 |
362-372 |
JJ |
denotes |
intestinal |
T340 |
373-375 |
NN |
denotes |
CF |
T341 |
385-386 |
. |
denotes |
. |
T342 |
386-669 |
sentence |
denotes |
CF mice on the mixed background exhibit significantly greater survival when fed dry mouse chow, have reduced intestinal inflammation as measured by quantitative RT-PCR for marker genes, have near normal body weight gain, and have reduced mucus accumulation in the intestinal crypts. |
T343 |
387-389 |
NN |
denotes |
CF |
T344 |
390-394 |
NNS |
denotes |
mice |
T345 |
419-426 |
VBP |
denotes |
exhibit |
T346 |
395-397 |
IN |
denotes |
on |
T347 |
398-401 |
DT |
denotes |
the |
T348 |
408-418 |
NN |
denotes |
background |
T349 |
402-407 |
JJ |
denotes |
mixed |
T350 |
427-440 |
RB |
denotes |
significantly |
T351 |
441-448 |
JJR |
denotes |
greater |
T352 |
449-457 |
NN |
denotes |
survival |
T353 |
458-462 |
WRB |
denotes |
when |
T354 |
463-466 |
VBN |
denotes |
fed |
T355 |
467-470 |
JJ |
denotes |
dry |
T356 |
477-481 |
NN |
denotes |
chow |
T357 |
471-476 |
NN |
denotes |
mouse |
T358 |
481-483 |
, |
denotes |
, |
T359 |
483-487 |
VBP |
denotes |
have |
T360 |
488-495 |
VBN |
denotes |
reduced |
T361 |
507-519 |
NN |
denotes |
inflammation |
T362 |
496-506 |
JJ |
denotes |
intestinal |
T363 |
520-522 |
IN |
denotes |
as |
T364 |
523-531 |
VBN |
denotes |
measured |
T365 |
532-534 |
IN |
denotes |
by |
T366 |
535-547 |
JJ |
denotes |
quantitative |
T367 |
551-554 |
NN |
denotes |
PCR |
T368 |
548-550 |
NN |
denotes |
RT |
T369 |
550-551 |
HYPH |
denotes |
- |
T370 |
555-558 |
IN |
denotes |
for |
T371 |
559-565 |
NN |
denotes |
marker |
T372 |
566-571 |
NNS |
denotes |
genes |
T373 |
571-573 |
, |
denotes |
, |
T374 |
573-577 |
VBP |
denotes |
have |
T375 |
578-582 |
RB |
denotes |
near |
T376 |
583-589 |
JJ |
denotes |
normal |
T377 |
602-606 |
NN |
denotes |
gain |
T378 |
590-594 |
NN |
denotes |
body |
T379 |
595-601 |
NN |
denotes |
weight |
T380 |
606-608 |
, |
denotes |
, |
T381 |
608-611 |
CC |
denotes |
and |
T382 |
612-616 |
VBP |
denotes |
have |
T383 |
617-624 |
VBN |
denotes |
reduced |
T384 |
631-643 |
NN |
denotes |
accumulation |
T385 |
625-630 |
NN |
denotes |
mucus |
T386 |
644-646 |
IN |
denotes |
in |
T387 |
647-650 |
DT |
denotes |
the |
T388 |
662-668 |
NNS |
denotes |
crypts |
T389 |
651-661 |
JJ |
denotes |
intestinal |
T390 |
668-669 |
. |
denotes |
. |
T391 |
669-892 |
sentence |
denotes |
There was an indication of a gender effect for body weight gain: males did not show a significant improvement at 4 weeks of age, but were of normal weight at 8 weeks, while females showed improvement at both 4 and 8 weeks. |
T392 |
670-675 |
EX |
denotes |
There |
T393 |
676-679 |
VBD |
denotes |
was |
T394 |
749-753 |
VB |
denotes |
show |
T395 |
680-682 |
DT |
denotes |
an |
T396 |
683-693 |
NN |
denotes |
indication |
T397 |
694-696 |
IN |
denotes |
of |
T398 |
697-698 |
DT |
denotes |
a |
T399 |
706-712 |
NN |
denotes |
effect |
T400 |
699-705 |
NN |
denotes |
gender |
T401 |
713-716 |
IN |
denotes |
for |
T402 |
717-721 |
NN |
denotes |
body |
T403 |
729-733 |
NN |
denotes |
gain |
T404 |
722-728 |
NN |
denotes |
weight |
T405 |
733-735 |
: |
denotes |
: |
T406 |
735-740 |
NNS |
denotes |
males |
T407 |
741-744 |
VBD |
denotes |
did |
T408 |
745-748 |
RB |
denotes |
not |
T409 |
754-755 |
DT |
denotes |
a |
T410 |
768-779 |
NN |
denotes |
improvement |
T411 |
756-767 |
JJ |
denotes |
significant |
T412 |
780-782 |
IN |
denotes |
at |
T413 |
783-784 |
CD |
denotes |
4 |
T414 |
785-790 |
NNS |
denotes |
weeks |
T415 |
791-793 |
IN |
denotes |
of |
T416 |
794-797 |
NN |
denotes |
age |
T417 |
797-799 |
, |
denotes |
, |
T418 |
799-802 |
CC |
denotes |
but |
T419 |
803-807 |
VBD |
denotes |
were |
T420 |
808-810 |
IN |
denotes |
of |
T421 |
811-817 |
JJ |
denotes |
normal |
T422 |
818-824 |
NN |
denotes |
weight |
T423 |
825-827 |
IN |
denotes |
at |
T424 |
828-829 |
CD |
denotes |
8 |
T425 |
830-835 |
NNS |
denotes |
weeks |
T426 |
835-837 |
, |
denotes |
, |
T427 |
837-842 |
IN |
denotes |
while |
T428 |
851-857 |
VBD |
denotes |
showed |
T429 |
843-850 |
NNS |
denotes |
females |
T430 |
858-869 |
NN |
denotes |
improvement |
T431 |
870-872 |
IN |
denotes |
at |
T432 |
873-877 |
CC |
denotes |
both |
T433 |
878-879 |
CD |
denotes |
4 |
T434 |
886-891 |
NNS |
denotes |
weeks |
T435 |
880-883 |
CC |
denotes |
and |
T436 |
884-885 |
CD |
denotes |
8 |
T437 |
891-892 |
. |
denotes |
. |
T439 |
893-895 |
IN |
denotes |
By |
T440 |
962-967 |
VBN |
denotes |
found |
T441 |
896-897 |
DT |
denotes |
a |
T442 |
933-941 |
NN |
denotes |
scanning |
T443 |
898-909 |
JJ |
denotes |
preliminary |
T444 |
910-916 |
NN |
denotes |
genome |
T445 |
917-921 |
JJ |
denotes |
wide |
T446 |
916-917 |
HYPH |
denotes |
- |
T447 |
922-925 |
NN |
denotes |
PCR |
T448 |
926-932 |
NN |
denotes |
allele |
T449 |
941-943 |
, |
denotes |
, |
T450 |
943-948 |
CD |
denotes |
three |
T451 |
949-956 |
NNS |
denotes |
regions |
T452 |
957-961 |
VBD |
denotes |
were |
T453 |
968-970 |
TO |
denotes |
to |
T455 |
971-973 |
VB |
denotes |
be |
T456 |
974-985 |
RB |
denotes |
potentially |
R116 |
T268 |
T267 |
dobj |
inflammation,have |
R117 |
T269 |
T268 |
prep |
of,inflammation |
R118 |
T270 |
T271 |
det |
the,intestine |
R119 |
T271 |
T269 |
pobj |
intestine,of |
R121 |
T273 |
T267 |
punct |
", ",have |
R122 |
T274 |
T267 |
cc |
and,have |
R123 |
T275 |
T267 |
conj |
are,have |
R124 |
T276 |
T277 |
quantmod |
about,30 |
R125 |
T277 |
T278 |
nummod |
30,% |
R126 |
T278 |
T279 |
npadvmod |
%,smaller |
R127 |
T279 |
T275 |
acomp |
smaller,are |
R128 |
T280 |
T279 |
prep |
than,smaller |
R129 |
T281 |
T282 |
amod |
wild,type |
R130 |
T282 |
T283 |
compound |
type,littermates |
R131 |
T283 |
T280 |
pobj |
littermates,than |
R133 |
T286 |
T287 |
prep |
In,identified |
R134 |
T288 |
T289 |
det |
this,work |
R135 |
T289 |
T286 |
pobj |
work,In |
R136 |
T290 |
T291 |
compound |
potential,loci |
R137 |
T291 |
T287 |
nsubjpass |
loci,identified |
R139 |
T293 |
T291 |
prep |
of,loci |
R140 |
T294 |
T295 |
det |
the,phenotype |
R141 |
T295 |
T293 |
pobj |
phenotype,of |
R144 |
T298 |
T287 |
auxpass |
were,identified |
R145 |
T299 |
T287 |
punct |
.,identified |
R146 |
T303 |
T304 |
compound |
CF,mice |
R147 |
T304 |
T305 |
nsubjpass |
mice,compared |
R148 |
T306 |
T304 |
prep |
on,mice |
R149 |
T307 |
T308 |
det |
a,background |
R150 |
T308 |
T306 |
pobj |
background,on |
R153 |
T311 |
T312 |
punct |
(,C57Bl |
R154 |
T312 |
T304 |
parataxis |
C57Bl,mice |
R157 |
T315 |
T312 |
punct |
/,C57Bl |
R158 |
T316 |
T312 |
nummod |
6,C57Bl |
R159 |
T317 |
T312 |
cc |
and,C57Bl |
R160 |
T318 |
T319 |
nummod |
5,129Sv |
R161 |
T319 |
T312 |
conj |
129Sv,C57Bl |
R163 |
T321 |
T312 |
punct |
),C57Bl |
R164 |
T322 |
T305 |
auxpass |
were,compared |
R165 |
T323 |
T305 |
prep |
to,compared |
R166 |
T324 |
T325 |
compound |
CF,mice |
R167 |
T325 |
T323 |
pobj |
mice,to |
R168 |
T326 |
T325 |
amod |
congenic,mice |
R169 |
T327 |
T326 |
prep |
on,congenic |
R170 |
T328 |
T329 |
det |
the,background |
R171 |
T329 |
T327 |
pobj |
background,on |
R175 |
T333 |
T305 |
prep |
for,compared |
R176 |
T334 |
T335 |
amod |
several,parameters |
R177 |
T335 |
T333 |
pobj |
parameters,for |
R178 |
T336 |
T335 |
prep |
of,parameters |
R179 |
T337 |
T338 |
det |
the,phenotype |
R180 |
T338 |
T336 |
pobj |
phenotype,of |
R183 |
T341 |
T305 |
punct |
.,compared |
R184 |
T343 |
T344 |
compound |
CF,mice |
R185 |
T344 |
T345 |
nsubj |
mice,exhibit |
R186 |
T346 |
T344 |
prep |
on,mice |
R187 |
T347 |
T348 |
det |
the,background |
R188 |
T348 |
T346 |
pobj |
background,on |
R190 |
T350 |
T351 |
advmod |
significantly,greater |
R191 |
T351 |
T352 |
amod |
greater,survival |
R192 |
T352 |
T345 |
dobj |
survival,exhibit |
R193 |
T353 |
T354 |
advmod |
when,fed |
R194 |
T354 |
T345 |
advcl |
fed,exhibit |
R195 |
T355 |
T356 |
amod |
dry,chow |
R196 |
T356 |
T354 |
dobj |
chow,fed |
R198 |
T358 |
T345 |
punct |
", ",exhibit |
R199 |
T359 |
T345 |
conj |
have,exhibit |
R200 |
T360 |
T361 |
amod |
reduced,inflammation |
R201 |
T361 |
T359 |
dobj |
inflammation,have |
R203 |
T363 |
T364 |
mark |
as,measured |
R204 |
T364 |
T359 |
advcl |
measured,have |
R205 |
T365 |
T364 |
prep |
by,measured |
R206 |
T366 |
T367 |
amod |
quantitative,PCR |
R207 |
T367 |
T365 |
pobj |
PCR,by |
R210 |
T370 |
T367 |
prep |
for,PCR |
R211 |
T371 |
T372 |
compound |
marker,genes |
R212 |
T372 |
T370 |
pobj |
genes,for |
R213 |
T373 |
T359 |
punct |
", ",have |
R214 |
T374 |
T359 |
conj |
have,have |
R215 |
T375 |
T376 |
advmod |
near,normal |
R216 |
T376 |
T377 |
amod |
normal,gain |
R217 |
T377 |
T374 |
dobj |
gain,have |
R220 |
T380 |
T374 |
punct |
", ",have |
R221 |
T381 |
T374 |
cc |
and,have |
R222 |
T382 |
T374 |
conj |
have,have |
R223 |
T383 |
T384 |
amod |
reduced,accumulation |
R224 |
T384 |
T382 |
dobj |
accumulation,have |
R226 |
T386 |
T382 |
prep |
in,have |
R227 |
T387 |
T388 |
det |
the,crypts |
R228 |
T388 |
T386 |
pobj |
crypts,in |
R230 |
T390 |
T345 |
punct |
.,exhibit |
R231 |
T392 |
T393 |
expl |
There,was |
R232 |
T393 |
T394 |
ccomp |
was,show |
R233 |
T395 |
T396 |
det |
an,indication |
R234 |
T396 |
T393 |
attr |
indication,was |
R235 |
T397 |
T396 |
prep |
of,indication |
R236 |
T398 |
T399 |
det |
a,effect |
R237 |
T399 |
T397 |
pobj |
effect,of |
R239 |
T401 |
T399 |
prep |
for,effect |
R240 |
T402 |
T403 |
compound |
body,gain |
R241 |
T403 |
T401 |
pobj |
gain,for |
R243 |
T405 |
T394 |
punct |
: ,show |
R244 |
T406 |
T394 |
nsubj |
males,show |
R245 |
T407 |
T394 |
aux |
did,show |
R246 |
T408 |
T394 |
neg |
not,show |
R247 |
T409 |
T410 |
det |
a,improvement |
R248 |
T410 |
T394 |
dobj |
improvement,show |
R250 |
T412 |
T394 |
prep |
at,show |
R251 |
T413 |
T414 |
nummod |
4,weeks |
R252 |
T414 |
T412 |
pobj |
weeks,at |
R253 |
T415 |
T414 |
prep |
of,weeks |
R254 |
T416 |
T415 |
pobj |
age,of |
R255 |
T417 |
T394 |
punct |
", ",show |
R256 |
T418 |
T394 |
cc |
but,show |
R257 |
T419 |
T394 |
conj |
were,show |
R258 |
T420 |
T419 |
prep |
of,were |
R259 |
T421 |
T422 |
amod |
normal,weight |
R260 |
T422 |
T420 |
pobj |
weight,of |
R261 |
T423 |
T419 |
prep |
at,were |
R262 |
T424 |
T425 |
nummod |
8,weeks |
R263 |
T425 |
T423 |
pobj |
weeks,at |
R264 |
T426 |
T394 |
punct |
", ",show |
R265 |
T427 |
T428 |
mark |
while,showed |
R266 |
T428 |
T394 |
advcl |
showed,show |
R268 |
T430 |
T428 |
dobj |
improvement,showed |
R269 |
T431 |
T428 |
prep |
at,showed |
R270 |
T432 |
T433 |
preconj |
both,4 |
R271 |
T433 |
T434 |
nummod |
4,weeks |
R272 |
T434 |
T431 |
pobj |
weeks,at |
R275 |
T437 |
T394 |
punct |
.,show |
R276 |
T439 |
T440 |
prep |
By,found |
R277 |
T441 |
T442 |
det |
a,scanning |
R278 |
T442 |
T439 |
pobj |
scanning,By |
R281 |
T445 |
T442 |
amod |
wide,scanning |
R282 |
T446 |
T445 |
punct |
-,wide |
R285 |
T449 |
T440 |
punct |
", ",found |
R286 |
T450 |
T451 |
nummod |
three,regions |
R287 |
T451 |
T440 |
nsubjpass |
regions,found |
R288 |
T452 |
T440 |
auxpass |
were,found |
R113 |
T265 |
T264 |
compound |
mouse,chow |
R120 |
T272 |
T271 |
amod |
small,intestine |
R138 |
T292 |
T291 |
compound |
modifier,loci |
R142 |
T296 |
T295 |
nmod |
CF,phenotype |
R143 |
T297 |
T295 |
amod |
intestinal,phenotype |
R151 |
T309 |
T308 |
amod |
mixed,background |
R152 |
T310 |
T308 |
amod |
genetic,background |
R155 |
T313 |
T312 |
nummod |
95,C57Bl |
R156 |
T314 |
T313 |
quantmod |
%,95 |
R162 |
T320 |
T318 |
quantmod |
%,5 |
R172 |
T330 |
T329 |
nmod |
C57Bl,background |
R173 |
T331 |
T330 |
punct |
/,C57Bl |
R174 |
T332 |
T330 |
nummod |
6,C57Bl |
R181 |
T339 |
T338 |
amod |
intestinal,phenotype |
R182 |
T340 |
T338 |
compound |
CF,phenotype |
R189 |
T349 |
T348 |
amod |
mixed,background |
R197 |
T357 |
T356 |
compound |
mouse,chow |
R202 |
T362 |
T361 |
amod |
intestinal,inflammation |
R208 |
T368 |
T367 |
compound |
RT,PCR |
R209 |
T369 |
T367 |
punct |
-,PCR |
R218 |
T378 |
T379 |
compound |
body,weight |
R219 |
T379 |
T377 |
compound |
weight,gain |
R225 |
T385 |
T384 |
compound |
mucus,accumulation |
R229 |
T389 |
T388 |
amod |
intestinal,crypts |
R238 |
T400 |
T399 |
compound |
gender,effect |
R242 |
T404 |
T403 |
compound |
weight,gain |
R249 |
T411 |
T410 |
amod |
significant,improvement |
R267 |
T429 |
T428 |
nsubj |
females,showed |
R273 |
T435 |
T433 |
cc |
and,4 |
R274 |
T436 |
T433 |
conj |
8,4 |
R279 |
T443 |
T442 |
amod |
preliminary,scanning |
R280 |
T444 |
T445 |
npadvmod |
genome,wide |
R283 |
T447 |
T448 |
compound |
PCR,allele |
R284 |
T448 |
T442 |
compound |
allele,scanning |