| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T139 |
0-9 |
JJ |
denotes |
Potential |
| T140 |
18-27 |
NNS |
denotes |
modifiers |
| T141 |
0-118 |
sentence |
denotes |
Potential genetic modifiers of the cystic fibrosis intestinal inflammatory phenotype on mouse chromosomes 1, 9, and 10 |
| T142 |
10-17 |
JJ |
denotes |
genetic |
| T143 |
28-30 |
IN |
denotes |
of |
| T144 |
31-34 |
DT |
denotes |
the |
| T145 |
75-84 |
NN |
denotes |
phenotype |
| T146 |
35-41 |
JJ |
denotes |
cystic |
| T147 |
42-50 |
NN |
denotes |
fibrosis |
| T148 |
51-61 |
JJ |
denotes |
intestinal |
| T149 |
62-74 |
JJ |
denotes |
inflammatory |
| T150 |
85-87 |
IN |
denotes |
on |
| T151 |
88-93 |
NN |
denotes |
mouse |
| T152 |
106-107 |
CD |
denotes |
1 |
| T153 |
94-105 |
NNS |
denotes |
chromosomes |
| T155 |
109-110 |
CD |
denotes |
9 |
| T156 |
110-112 |
, |
denotes |
, |
| T157 |
112-115 |
CC |
denotes |
and |
| T158 |
116-118 |
CD |
denotes |
10 |
| T159 |
118-119 |
sentence |
denotes |
|
| T160 |
129-139 |
sentence |
denotes |
Background |
| T161 |
129-139 |
NN |
denotes |
Background |
| T162 |
139-346 |
sentence |
denotes |
Although cystic fibrosis is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the severity of disease is highly variable indicating the influence of modifier genes. |
| T163 |
140-148 |
IN |
denotes |
Although |
| T164 |
168-174 |
VBN |
denotes |
caused |
| T165 |
149-155 |
JJ |
denotes |
cystic |
| T166 |
156-164 |
NN |
denotes |
fibrosis |
| T167 |
165-167 |
VBZ |
denotes |
is |
| T168 |
284-286 |
VBZ |
denotes |
is |
| T169 |
175-177 |
IN |
denotes |
by |
| T170 |
178-187 |
NNS |
denotes |
mutations |
| T171 |
188-190 |
IN |
denotes |
in |
| T172 |
191-194 |
DT |
denotes |
the |
| T173 |
254-258 |
NN |
denotes |
gene |
| T174 |
195-201 |
JJ |
denotes |
cystic |
| T175 |
237-246 |
NN |
denotes |
regulator |
| T176 |
202-210 |
NN |
denotes |
fibrosis |
| T177 |
211-224 |
JJ |
denotes |
transmembrane |
| T178 |
225-236 |
NN |
denotes |
conductance |
| T179 |
247-248 |
-LRB- |
denotes |
( |
| T180 |
248-252 |
NN |
denotes |
CFTR |
| T181 |
252-253 |
-RRB- |
denotes |
) |
| T182 |
258-260 |
, |
denotes |
, |
| T183 |
260-263 |
DT |
denotes |
the |
| T184 |
264-272 |
NN |
denotes |
severity |
| T185 |
273-275 |
IN |
denotes |
of |
| T186 |
276-283 |
NN |
denotes |
disease |
| T187 |
287-293 |
RB |
denotes |
highly |
| T188 |
294-302 |
JJ |
denotes |
variable |
| T189 |
303-313 |
VBG |
denotes |
indicating |
| T190 |
314-317 |
DT |
denotes |
the |
| T191 |
318-327 |
NN |
denotes |
influence |
| T192 |
328-330 |
IN |
denotes |
of |
| T193 |
331-339 |
NN |
denotes |
modifier |
| T194 |
340-345 |
NNS |
denotes |
genes |
| T195 |
345-346 |
. |
denotes |
. |
| T196 |
346-549 |
sentence |
denotes |
The intestines of Cftr deficient mice (CF mice: Cftrtm1Unc) are prone to obstruction by excessive mucus accumulation and are used as a model of meconium ileus and distal intestinal obstruction syndrome. |
| T197 |
347-350 |
DT |
denotes |
The |
| T198 |
351-361 |
NNS |
denotes |
intestines |
| T199 |
407-410 |
VBP |
denotes |
are |
| T200 |
362-364 |
IN |
denotes |
of |
| T201 |
365-369 |
NN |
denotes |
Cftr |
| T202 |
370-379 |
JJ |
denotes |
deficient |
| T203 |
380-384 |
NNS |
denotes |
mice |
| T204 |
385-386 |
-LRB- |
denotes |
( |
| T205 |
386-388 |
NN |
denotes |
CF |
| T206 |
389-393 |
NNS |
denotes |
mice |
| T207 |
393-395 |
: |
denotes |
: |
| T208 |
395-405 |
NN |
denotes |
Cftrtm1Unc |
| T209 |
405-406 |
-RRB- |
denotes |
) |
| T210 |
411-416 |
JJ |
denotes |
prone |
| T211 |
417-419 |
IN |
denotes |
to |
| T212 |
420-431 |
NN |
denotes |
obstruction |
| T213 |
432-434 |
IN |
denotes |
by |
| T214 |
435-444 |
JJ |
denotes |
excessive |
| T215 |
451-463 |
NN |
denotes |
accumulation |
| T216 |
445-450 |
NN |
denotes |
mucus |
| T217 |
464-467 |
CC |
denotes |
and |
| T218 |
468-471 |
VBP |
denotes |
are |
| T219 |
472-476 |
VBN |
denotes |
used |
| T220 |
477-479 |
IN |
denotes |
as |
| T221 |
480-481 |
DT |
denotes |
a |
| T222 |
482-487 |
NN |
denotes |
model |
| T223 |
488-490 |
IN |
denotes |
of |
| T224 |
491-499 |
NN |
denotes |
meconium |
| T225 |
500-505 |
NN |
denotes |
ileus |
| T226 |
506-509 |
CC |
denotes |
and |
| T227 |
510-516 |
JJ |
denotes |
distal |
| T228 |
528-539 |
NN |
denotes |
obstruction |
| T229 |
517-527 |
JJ |
denotes |
intestinal |
| T230 |
540-548 |
NN |
denotes |
syndrome |
| T231 |
548-549 |
. |
denotes |
. |
| T232 |
549-625 |
sentence |
denotes |
This phenotype is strongly dependent on the genetic background of the mice. |
| T233 |
550-554 |
DT |
denotes |
This |
| T234 |
555-564 |
NN |
denotes |
phenotype |
| T235 |
565-567 |
VBZ |
denotes |
is |
| T236 |
568-576 |
RB |
denotes |
strongly |
| T237 |
577-586 |
JJ |
denotes |
dependent |
| T238 |
587-589 |
IN |
denotes |
on |
| T239 |
590-593 |
DT |
denotes |
the |
| T240 |
602-612 |
NN |
denotes |
background |
| T241 |
594-601 |
JJ |
denotes |
genetic |
| T242 |
613-615 |
IN |
denotes |
of |
| T243 |
616-619 |
DT |
denotes |
the |
| T244 |
620-624 |
NNS |
denotes |
mice |
| T245 |
624-625 |
. |
denotes |
. |
| T246 |
625-808 |
sentence |
denotes |
On the C57Bl/6 background, the majority of CF mice cannot survive on solid mouse chow, have inflammation of the small intestine, and are about 30% smaller than wild type littermates. |
| T247 |
626-628 |
IN |
denotes |
On |
| T248 |
684-691 |
VB |
denotes |
survive |
| T249 |
629-632 |
DT |
denotes |
the |
| T250 |
641-651 |
NN |
denotes |
background |
| T251 |
633-638 |
NN |
denotes |
C57Bl |
| T252 |
638-639 |
HYPH |
denotes |
/ |
| T253 |
639-640 |
CD |
denotes |
6 |
| T254 |
651-653 |
, |
denotes |
, |
| T255 |
653-656 |
DT |
denotes |
the |
| T256 |
657-665 |
NN |
denotes |
majority |
| T257 |
666-668 |
IN |
denotes |
of |
| T258 |
669-671 |
NN |
denotes |
CF |
| T259 |
672-676 |
NNS |
denotes |
mice |
| T260 |
677-680 |
MD |
denotes |
can |
| T261 |
680-683 |
RB |
denotes |
not |
| T262 |
692-694 |
IN |
denotes |
on |
| T263 |
695-700 |
JJ |
denotes |
solid |
| T264 |
707-711 |
NN |
denotes |
chow |
| T265 |
701-706 |
NN |
denotes |
mouse |
| T266 |
711-713 |
, |
denotes |
, |
| T267 |
713-717 |
VBP |
denotes |
have |
| T268 |
718-730 |
NN |
denotes |
inflammation |
| T269 |
731-733 |
IN |
denotes |
of |
| T270 |
734-737 |
DT |
denotes |
the |
| T271 |
744-753 |
NN |
denotes |
intestine |
| T272 |
738-743 |
JJ |
denotes |
small |
| T273 |
753-755 |
, |
denotes |
, |
| T274 |
755-758 |
CC |
denotes |
and |
| T275 |
759-762 |
VBP |
denotes |
are |
| T276 |
763-768 |
IN |
denotes |
about |
| T277 |
769-771 |
CD |
denotes |
30 |
| T278 |
771-772 |
NN |
denotes |
% |
| T279 |
773-780 |
JJR |
denotes |
smaller |
| T280 |
781-785 |
IN |
denotes |
than |
| T281 |
786-790 |
JJ |
denotes |
wild |
| T282 |
791-795 |
NN |
denotes |
type |
| T283 |
796-807 |
NNS |
denotes |
littermates |
| T284 |
807-808 |
. |
denotes |
. |
| T285 |
808-893 |
sentence |
denotes |
In this work potential modifier loci of the CF intestinal phenotype were identified. |
| T286 |
809-811 |
IN |
denotes |
In |
| T287 |
882-892 |
VBN |
denotes |
identified |
| T288 |
812-816 |
DT |
denotes |
this |
| T289 |
817-821 |
NN |
denotes |
work |
| T290 |
822-831 |
NN |
denotes |
potential |
| T291 |
841-845 |
NNS |
denotes |
loci |
| T292 |
832-840 |
NN |
denotes |
modifier |
| T293 |
846-848 |
IN |
denotes |
of |
| T294 |
849-852 |
DT |
denotes |
the |
| T295 |
867-876 |
NN |
denotes |
phenotype |
| T296 |
853-855 |
NN |
denotes |
CF |
| T297 |
856-866 |
JJ |
denotes |
intestinal |
| T298 |
877-881 |
VBD |
denotes |
were |
| T299 |
892-893 |
. |
denotes |
. |
| T300 |
893-902 |
sentence |
denotes |
Results |
| T301 |
895-902 |
NNS |
denotes |
Results |
| T302 |
902-1082 |
sentence |
denotes |
CF mice on a mixed genetic background (95% C57Bl/6 and 5% 129Sv) were compared to CF mice congenic on the C57Bl/6 background for several parameters of the intestinal CF phenotype. |
| T303 |
903-905 |
NN |
denotes |
CF |
| T304 |
906-910 |
NNS |
denotes |
mice |
| T305 |
973-981 |
VBN |
denotes |
compared |
| T306 |
911-913 |
IN |
denotes |
on |
| T307 |
914-915 |
DT |
denotes |
a |
| T308 |
930-940 |
NN |
denotes |
background |
| T309 |
916-921 |
JJ |
denotes |
mixed |
| T310 |
922-929 |
JJ |
denotes |
genetic |
| T311 |
941-942 |
-LRB- |
denotes |
( |
| T312 |
946-951 |
NN |
denotes |
C57Bl |
| T313 |
942-944 |
CD |
denotes |
95 |
| T314 |
944-945 |
NN |
denotes |
% |
| T315 |
951-952 |
HYPH |
denotes |
/ |
| T316 |
952-953 |
CD |
denotes |
6 |
| T317 |
954-957 |
CC |
denotes |
and |
| T318 |
958-959 |
CD |
denotes |
5 |
| T319 |
961-966 |
NN |
denotes |
129Sv |
| T320 |
959-960 |
NN |
denotes |
% |
| T321 |
966-967 |
-RRB- |
denotes |
) |
| T322 |
968-972 |
VBD |
denotes |
were |
| T323 |
982-984 |
IN |
denotes |
to |
| T324 |
985-987 |
NN |
denotes |
CF |
| T325 |
988-992 |
NNS |
denotes |
mice |
| T326 |
993-1001 |
JJ |
denotes |
congenic |
| T327 |
1002-1004 |
IN |
denotes |
on |
| T328 |
1005-1008 |
DT |
denotes |
the |
| T329 |
1017-1027 |
NN |
denotes |
background |
| T330 |
1009-1014 |
NN |
denotes |
C57Bl |
| T331 |
1014-1015 |
HYPH |
denotes |
/ |
| T332 |
1015-1016 |
CD |
denotes |
6 |
| T333 |
1028-1031 |
IN |
denotes |
for |
| T334 |
1032-1039 |
JJ |
denotes |
several |
| T335 |
1040-1050 |
NNS |
denotes |
parameters |
| T336 |
1051-1053 |
IN |
denotes |
of |
| T337 |
1054-1057 |
DT |
denotes |
the |
| T338 |
1072-1081 |
NN |
denotes |
phenotype |
| T339 |
1058-1068 |
JJ |
denotes |
intestinal |
| T340 |
1069-1071 |
NN |
denotes |
CF |
| T341 |
1081-1082 |
. |
denotes |
. |
| T342 |
1082-1365 |
sentence |
denotes |
CF mice on the mixed background exhibit significantly greater survival when fed dry mouse chow, have reduced intestinal inflammation as measured by quantitative RT-PCR for marker genes, have near normal body weight gain, and have reduced mucus accumulation in the intestinal crypts. |
| T343 |
1083-1085 |
NN |
denotes |
CF |
| T344 |
1086-1090 |
NNS |
denotes |
mice |
| T345 |
1115-1122 |
VBP |
denotes |
exhibit |
| T346 |
1091-1093 |
IN |
denotes |
on |
| T347 |
1094-1097 |
DT |
denotes |
the |
| T348 |
1104-1114 |
NN |
denotes |
background |
| T349 |
1098-1103 |
JJ |
denotes |
mixed |
| T350 |
1123-1136 |
RB |
denotes |
significantly |
| T351 |
1137-1144 |
JJR |
denotes |
greater |
| T352 |
1145-1153 |
NN |
denotes |
survival |
| T353 |
1154-1158 |
WRB |
denotes |
when |
| T354 |
1159-1162 |
VBN |
denotes |
fed |
| T355 |
1163-1166 |
JJ |
denotes |
dry |
| T356 |
1173-1177 |
NN |
denotes |
chow |
| T357 |
1167-1172 |
NN |
denotes |
mouse |
| T358 |
1177-1179 |
, |
denotes |
, |
| T359 |
1179-1183 |
VBP |
denotes |
have |
| T360 |
1184-1191 |
VBN |
denotes |
reduced |
| T361 |
1203-1215 |
NN |
denotes |
inflammation |
| T362 |
1192-1202 |
JJ |
denotes |
intestinal |
| T363 |
1216-1218 |
IN |
denotes |
as |
| T364 |
1219-1227 |
VBN |
denotes |
measured |
| T365 |
1228-1230 |
IN |
denotes |
by |
| T366 |
1231-1243 |
JJ |
denotes |
quantitative |
| T367 |
1247-1250 |
NN |
denotes |
PCR |
| T368 |
1244-1246 |
NN |
denotes |
RT |
| T369 |
1246-1247 |
HYPH |
denotes |
- |
| T370 |
1251-1254 |
IN |
denotes |
for |
| T371 |
1255-1261 |
NN |
denotes |
marker |
| T372 |
1262-1267 |
NNS |
denotes |
genes |
| T373 |
1267-1269 |
, |
denotes |
, |
| T374 |
1269-1273 |
VBP |
denotes |
have |
| T375 |
1274-1278 |
RB |
denotes |
near |
| T376 |
1279-1285 |
JJ |
denotes |
normal |
| T377 |
1298-1302 |
NN |
denotes |
gain |
| T378 |
1286-1290 |
NN |
denotes |
body |
| T379 |
1291-1297 |
NN |
denotes |
weight |
| T380 |
1302-1304 |
, |
denotes |
, |
| T381 |
1304-1307 |
CC |
denotes |
and |
| T382 |
1308-1312 |
VBP |
denotes |
have |
| T383 |
1313-1320 |
VBN |
denotes |
reduced |
| T384 |
1327-1339 |
NN |
denotes |
accumulation |
| T385 |
1321-1326 |
NN |
denotes |
mucus |
| T386 |
1340-1342 |
IN |
denotes |
in |
| T387 |
1343-1346 |
DT |
denotes |
the |
| T388 |
1358-1364 |
NNS |
denotes |
crypts |
| T389 |
1347-1357 |
JJ |
denotes |
intestinal |
| T390 |
1364-1365 |
. |
denotes |
. |
| T392 |
1366-1371 |
EX |
denotes |
There |
| T393 |
1372-1375 |
VBD |
denotes |
was |
| T394 |
1445-1449 |
VB |
denotes |
show |
| T395 |
1376-1378 |
DT |
denotes |
an |
| T396 |
1379-1389 |
NN |
denotes |
indication |
| T397 |
1390-1392 |
IN |
denotes |
of |
| T398 |
1393-1394 |
DT |
denotes |
a |
| T399 |
1402-1408 |
NN |
denotes |
effect |
| T400 |
1395-1401 |
NN |
denotes |
gender |
| T401 |
1409-1412 |
IN |
denotes |
for |
| T402 |
1413-1417 |
NN |
denotes |
body |
| T403 |
1425-1429 |
NN |
denotes |
gain |
| T404 |
1418-1424 |
NN |
denotes |
weight |
| T405 |
1429-1431 |
: |
denotes |
: |
| T406 |
1431-1436 |
NNS |
denotes |
males |
| T407 |
1437-1440 |
VBD |
denotes |
did |
| T408 |
1441-1444 |
RB |
denotes |
not |
| T409 |
1450-1451 |
DT |
denotes |
a |
| T410 |
1464-1475 |
NN |
denotes |
improvement |
| T411 |
1452-1463 |
JJ |
denotes |
significant |
| T412 |
1476-1478 |
IN |
denotes |
at |
| T413 |
1479-1480 |
CD |
denotes |
4 |
| T414 |
1481-1486 |
NNS |
denotes |
weeks |
| T415 |
1487-1489 |
IN |
denotes |
of |
| T416 |
1490-1493 |
NN |
denotes |
age |
| T417 |
1493-1495 |
, |
denotes |
, |
| T418 |
1495-1498 |
CC |
denotes |
but |
| T419 |
1499-1503 |
VBD |
denotes |
were |
| T420 |
1504-1506 |
IN |
denotes |
of |
| T421 |
1507-1513 |
JJ |
denotes |
normal |
| T422 |
1514-1520 |
NN |
denotes |
weight |
| T423 |
1521-1523 |
IN |
denotes |
at |
| T424 |
1524-1525 |
CD |
denotes |
8 |
| T425 |
1526-1531 |
NNS |
denotes |
weeks |
| T426 |
1531-1533 |
, |
denotes |
, |
| T427 |
1533-1538 |
IN |
denotes |
while |
| T428 |
1547-1553 |
VBD |
denotes |
showed |
| T429 |
1539-1546 |
NNS |
denotes |
females |
| T430 |
1554-1565 |
NN |
denotes |
improvement |
| T431 |
1566-1568 |
IN |
denotes |
at |
| T432 |
1569-1573 |
CC |
denotes |
both |
| T433 |
1574-1575 |
CD |
denotes |
4 |
| T435 |
1576-1579 |
CC |
denotes |
and |
| T154 |
107-109 |
, |
denotes |
, |
| R79 |
T227 |
T228 |
amod |
distal,obstruction |
| R5 |
T145 |
T143 |
pobj |
phenotype,of |
| R6 |
T146 |
T147 |
amod |
cystic,fibrosis |
| R7 |
T147 |
T145 |
nmod |
fibrosis,phenotype |
| R8 |
T148 |
T145 |
amod |
intestinal,phenotype |
| R9 |
T149 |
T145 |
amod |
inflammatory,phenotype |
| R12 |
T152 |
T150 |
pobj |
1,on |
| R13 |
T153 |
T152 |
nmod |
chromosomes,1 |
| R14 |
T155 |
T152 |
conj |
9,1 |
| R15 |
T156 |
T155 |
punct |
", ",9 |
| R16 |
T157 |
T155 |
cc |
and,9 |
| R17 |
T158 |
T155 |
conj |
10,9 |
| R18 |
T163 |
T164 |
mark |
Although,caused |
| R19 |
T164 |
T168 |
advcl |
caused,is |
| R23 |
T169 |
T164 |
agent |
by,caused |
| R24 |
T170 |
T169 |
pobj |
mutations,by |
| R25 |
T171 |
T170 |
prep |
in,mutations |
| R26 |
T172 |
T173 |
det |
the,gene |
| R27 |
T173 |
T171 |
pobj |
gene,in |
| R29 |
T175 |
T173 |
nmod |
regulator,gene |
| R30 |
T176 |
T175 |
nmod |
fibrosis,regulator |
| R31 |
T177 |
T175 |
amod |
transmembrane,regulator |
| R32 |
T178 |
T175 |
nmod |
conductance,regulator |
| R36 |
T182 |
T168 |
punct |
", ",is |
| R37 |
T183 |
T184 |
det |
the,severity |
| R38 |
T184 |
T168 |
nsubj |
severity,is |
| R39 |
T185 |
T184 |
prep |
of,severity |
| R40 |
T186 |
T185 |
pobj |
disease,of |
| R41 |
T187 |
T188 |
advmod |
highly,variable |
| R42 |
T188 |
T168 |
acomp |
variable,is |
| R43 |
T189 |
T168 |
advcl |
indicating,is |
| R44 |
T190 |
T191 |
det |
the,influence |
| R45 |
T191 |
T189 |
dobj |
influence,indicating |
| R46 |
T192 |
T191 |
prep |
of,influence |
| R47 |
T193 |
T194 |
compound |
modifier,genes |
| R48 |
T194 |
T192 |
pobj |
genes,of |
| R49 |
T195 |
T168 |
punct |
.,is |
| R50 |
T197 |
T198 |
det |
The,intestines |
| R51 |
T198 |
T199 |
nsubj |
intestines,are |
| R52 |
T200 |
T198 |
prep |
of,intestines |
| R53 |
T201 |
T202 |
npadvmod |
Cftr,deficient |
| R54 |
T202 |
T203 |
amod |
deficient,mice |
| R55 |
T203 |
T200 |
pobj |
mice,of |
| R56 |
T204 |
T203 |
punct |
(,mice |
| R57 |
T205 |
T206 |
compound |
CF,mice |
| R58 |
T206 |
T203 |
appos |
mice,mice |
| R59 |
T207 |
T206 |
punct |
: ,mice |
| R60 |
T208 |
T206 |
appos |
Cftrtm1Unc,mice |
| R61 |
T209 |
T199 |
punct |
),are |
| R62 |
T210 |
T199 |
acomp |
prone,are |
| R63 |
T211 |
T210 |
prep |
to,prone |
| R64 |
T212 |
T211 |
pobj |
obstruction,to |
| R65 |
T213 |
T212 |
prep |
by,obstruction |
| R66 |
T214 |
T215 |
amod |
excessive,accumulation |
| R67 |
T215 |
T213 |
pobj |
accumulation,by |
| R69 |
T217 |
T199 |
cc |
and,are |
| R70 |
T218 |
T219 |
auxpass |
are,used |
| R71 |
T219 |
T199 |
conj |
used,are |
| R72 |
T220 |
T219 |
prep |
as,used |
| R73 |
T221 |
T222 |
det |
a,model |
| R74 |
T222 |
T220 |
pobj |
model,as |
| R75 |
T223 |
T222 |
prep |
of,model |
| R76 |
T224 |
T225 |
compound |
meconium,ileus |
| R77 |
T225 |
T223 |
pobj |
ileus,of |
| R78 |
T226 |
T225 |
cc |
and,ileus |
| R80 |
T228 |
T230 |
compound |
obstruction,syndrome |
| R82 |
T230 |
T225 |
conj |
syndrome,ileus |
| R83 |
T231 |
T199 |
punct |
.,are |
| R84 |
T233 |
T234 |
det |
This,phenotype |
| R85 |
T234 |
T235 |
nsubj |
phenotype,is |
| R86 |
T236 |
T237 |
advmod |
strongly,dependent |
| R87 |
T237 |
T235 |
acomp |
dependent,is |
| R88 |
T238 |
T237 |
prep |
on,dependent |
| R89 |
T239 |
T240 |
det |
the,background |
| R90 |
T240 |
T238 |
pobj |
background,on |
| R92 |
T242 |
T240 |
prep |
of,background |
| R93 |
T243 |
T244 |
det |
the,mice |
| R94 |
T244 |
T242 |
pobj |
mice,of |
| R95 |
T245 |
T235 |
punct |
.,is |
| R96 |
T247 |
T248 |
prep |
On,survive |
| R97 |
T249 |
T250 |
det |
the,background |
| R98 |
T250 |
T247 |
pobj |
background,On |
| R102 |
T254 |
T248 |
punct |
", ",survive |
| R103 |
T255 |
T256 |
det |
the,majority |
| R104 |
T256 |
T248 |
nsubj |
majority,survive |
| R105 |
T257 |
T256 |
prep |
of,majority |
| R106 |
T258 |
T259 |
compound |
CF,mice |
| R107 |
T259 |
T257 |
pobj |
mice,of |
| R108 |
T260 |
T248 |
aux |
can,survive |
| R109 |
T261 |
T248 |
neg |
not,survive |
| R110 |
T262 |
T248 |
prep |
on,survive |
| R111 |
T263 |
T264 |
amod |
solid,chow |
| R112 |
T264 |
T262 |
pobj |
chow,on |
| R114 |
T266 |
T248 |
punct |
", ",survive |
| R115 |
T267 |
T248 |
conj |
have,survive |
| R116 |
T268 |
T267 |
dobj |
inflammation,have |
| R117 |
T269 |
T268 |
prep |
of,inflammation |
| R118 |
T270 |
T271 |
det |
the,intestine |
| R119 |
T271 |
T269 |
pobj |
intestine,of |
| R121 |
T273 |
T267 |
punct |
", ",have |
| R122 |
T274 |
T267 |
cc |
and,have |
| R123 |
T275 |
T267 |
conj |
are,have |
| R124 |
T276 |
T277 |
quantmod |
about,30 |
| R125 |
T277 |
T278 |
nummod |
30,% |
| R126 |
T278 |
T279 |
npadvmod |
%,smaller |
| R127 |
T279 |
T275 |
acomp |
smaller,are |
| R128 |
T280 |
T279 |
prep |
than,smaller |
| R129 |
T281 |
T282 |
amod |
wild,type |
| R130 |
T282 |
T283 |
compound |
type,littermates |
| R131 |
T283 |
T280 |
pobj |
littermates,than |
| R132 |
T284 |
T248 |
punct |
.,survive |
| R133 |
T286 |
T287 |
prep |
In,identified |
| R134 |
T288 |
T289 |
det |
this,work |
| R135 |
T289 |
T286 |
pobj |
work,In |
| R136 |
T290 |
T291 |
compound |
potential,loci |
| R137 |
T291 |
T287 |
nsubjpass |
loci,identified |
| R139 |
T293 |
T291 |
prep |
of,loci |
| R140 |
T294 |
T295 |
det |
the,phenotype |
| R141 |
T295 |
T293 |
pobj |
phenotype,of |
| R144 |
T298 |
T287 |
auxpass |
were,identified |
| R145 |
T299 |
T287 |
punct |
.,identified |
| R146 |
T303 |
T304 |
compound |
CF,mice |
| R147 |
T304 |
T305 |
nsubjpass |
mice,compared |
| R148 |
T306 |
T304 |
prep |
on,mice |
| R149 |
T307 |
T308 |
det |
a,background |
| R150 |
T308 |
T306 |
pobj |
background,on |
| R153 |
T311 |
T312 |
punct |
(,C57Bl |
| R154 |
T312 |
T304 |
parataxis |
C57Bl,mice |
| R157 |
T315 |
T312 |
punct |
/,C57Bl |
| R158 |
T316 |
T312 |
nummod |
6,C57Bl |
| R159 |
T317 |
T312 |
cc |
and,C57Bl |
| R160 |
T318 |
T319 |
nummod |
5,129Sv |
| R161 |
T319 |
T312 |
conj |
129Sv,C57Bl |
| R163 |
T321 |
T312 |
punct |
),C57Bl |
| R164 |
T322 |
T305 |
auxpass |
were,compared |
| R165 |
T323 |
T305 |
prep |
to,compared |
| R166 |
T324 |
T325 |
compound |
CF,mice |
| R167 |
T325 |
T323 |
pobj |
mice,to |
| R168 |
T326 |
T325 |
amod |
congenic,mice |
| R169 |
T327 |
T326 |
prep |
on,congenic |
| R170 |
T328 |
T329 |
det |
the,background |
| R171 |
T329 |
T327 |
pobj |
background,on |
| R175 |
T333 |
T305 |
prep |
for,compared |
| R176 |
T334 |
T335 |
amod |
several,parameters |
| R177 |
T335 |
T333 |
pobj |
parameters,for |
| R178 |
T336 |
T335 |
prep |
of,parameters |
| R179 |
T337 |
T338 |
det |
the,phenotype |
| R180 |
T338 |
T336 |
pobj |
phenotype,of |
| R183 |
T341 |
T305 |
punct |
.,compared |
| R184 |
T343 |
T344 |
compound |
CF,mice |
| R185 |
T344 |
T345 |
nsubj |
mice,exhibit |
| R186 |
T346 |
T344 |
prep |
on,mice |
| R187 |
T347 |
T348 |
det |
the,background |
| R188 |
T348 |
T346 |
pobj |
background,on |
| R190 |
T350 |
T351 |
advmod |
significantly,greater |
| R191 |
T351 |
T352 |
amod |
greater,survival |
| R192 |
T352 |
T345 |
dobj |
survival,exhibit |
| R193 |
T353 |
T354 |
advmod |
when,fed |
| R194 |
T354 |
T345 |
advcl |
fed,exhibit |
| R195 |
T355 |
T356 |
amod |
dry,chow |
| R196 |
T356 |
T354 |
dobj |
chow,fed |
| R198 |
T358 |
T345 |
punct |
", ",exhibit |
| R199 |
T359 |
T345 |
conj |
have,exhibit |
| R200 |
T360 |
T361 |
amod |
reduced,inflammation |
| R201 |
T361 |
T359 |
dobj |
inflammation,have |
| R203 |
T363 |
T364 |
mark |
as,measured |
| R204 |
T364 |
T359 |
advcl |
measured,have |
| R205 |
T365 |
T364 |
prep |
by,measured |
| R206 |
T366 |
T367 |
amod |
quantitative,PCR |
| R207 |
T367 |
T365 |
pobj |
PCR,by |
| R210 |
T370 |
T367 |
prep |
for,PCR |
| R211 |
T371 |
T372 |
compound |
marker,genes |
| R212 |
T372 |
T370 |
pobj |
genes,for |
| R213 |
T373 |
T359 |
punct |
", ",have |
| R214 |
T374 |
T359 |
conj |
have,have |
| R215 |
T375 |
T376 |
advmod |
near,normal |
| R216 |
T376 |
T377 |
amod |
normal,gain |
| R217 |
T377 |
T374 |
dobj |
gain,have |
| R220 |
T380 |
T374 |
punct |
", ",have |
| R221 |
T381 |
T374 |
cc |
and,have |
| R222 |
T382 |
T374 |
conj |
have,have |
| R223 |
T383 |
T384 |
amod |
reduced,accumulation |
| R224 |
T384 |
T382 |
dobj |
accumulation,have |
| R226 |
T386 |
T382 |
prep |
in,have |
| R227 |
T387 |
T388 |
det |
the,crypts |
| R228 |
T388 |
T386 |
pobj |
crypts,in |
| R230 |
T390 |
T345 |
punct |
.,exhibit |
| R231 |
T392 |
T393 |
expl |
There,was |
| R232 |
T393 |
T394 |
ccomp |
was,show |
| R233 |
T395 |
T396 |
det |
an,indication |
| R234 |
T396 |
T393 |
attr |
indication,was |
| R235 |
T397 |
T396 |
prep |
of,indication |
| R236 |
T398 |
T399 |
det |
a,effect |
| R237 |
T399 |
T397 |
pobj |
effect,of |
| R239 |
T401 |
T399 |
prep |
for,effect |
| R240 |
T402 |
T403 |
compound |
body,gain |
| R241 |
T403 |
T401 |
pobj |
gain,for |
| R243 |
T405 |
T394 |
punct |
: ,show |
| R244 |
T406 |
T394 |
nsubj |
males,show |
| R245 |
T407 |
T394 |
aux |
did,show |
| R246 |
T408 |
T394 |
neg |
not,show |
| R247 |
T409 |
T410 |
det |
a,improvement |
| R248 |
T410 |
T394 |
dobj |
improvement,show |
| R250 |
T412 |
T394 |
prep |
at,show |
| R251 |
T413 |
T414 |
nummod |
4,weeks |
| R252 |
T414 |
T412 |
pobj |
weeks,at |
| R253 |
T415 |
T414 |
prep |
of,weeks |
| R254 |
T416 |
T415 |
pobj |
age,of |
| R255 |
T417 |
T394 |
punct |
", ",show |
| R256 |
T418 |
T394 |
cc |
but,show |
| R257 |
T419 |
T394 |
conj |
were,show |
| R258 |
T420 |
T419 |
prep |
of,were |
| R259 |
T421 |
T422 |
amod |
normal,weight |
| R260 |
T422 |
T420 |
pobj |
weight,of |
| R261 |
T423 |
T419 |
prep |
at,were |
| R262 |
T424 |
T425 |
nummod |
8,weeks |
| R263 |
T425 |
T423 |
pobj |
weeks,at |
| R264 |
T426 |
T394 |
punct |
", ",show |
| R265 |
T427 |
T428 |
mark |
while,showed |
| R266 |
T428 |
T394 |
advcl |
showed,show |
| R268 |
T430 |
T428 |
dobj |
improvement,showed |
| R269 |
T431 |
T428 |
prep |
at,showed |
| R270 |
T432 |
T433 |
preconj |
both,4 |
| R371 |
T154 |
T152 |
punct |
", ",1 |
| R1 |
T139 |
T140 |
amod |
Potential,modifiers |
| R2 |
T142 |
T140 |
amod |
genetic,modifiers |
| R3 |
T143 |
T140 |
prep |
of,modifiers |
| R4 |
T144 |
T145 |
det |
the,phenotype |
| R10 |
T150 |
T140 |
prep |
on,modifiers |
| R11 |
T151 |
T152 |
nmod |
mouse,1 |
| R20 |
T165 |
T166 |
amod |
cystic,fibrosis |
| R21 |
T166 |
T164 |
nsubjpass |
fibrosis,caused |
| R22 |
T167 |
T164 |
auxpass |
is,caused |
| R28 |
T174 |
T175 |
amod |
cystic,regulator |
| R33 |
T179 |
T175 |
punct |
(,regulator |
| R34 |
T180 |
T175 |
appos |
CFTR,regulator |
| R35 |
T181 |
T173 |
punct |
),gene |
| R68 |
T216 |
T215 |
compound |
mucus,accumulation |
| R81 |
T229 |
T228 |
amod |
intestinal,obstruction |
| R91 |
T241 |
T240 |
amod |
genetic,background |
| R99 |
T251 |
T250 |
nmod |
C57Bl,background |
| R100 |
T252 |
T251 |
punct |
/,C57Bl |
| R101 |
T253 |
T251 |
nummod |
6,C57Bl |
| R113 |
T265 |
T264 |
compound |
mouse,chow |
| R120 |
T272 |
T271 |
amod |
small,intestine |
| R138 |
T292 |
T291 |
compound |
modifier,loci |
| R142 |
T296 |
T295 |
nmod |
CF,phenotype |
| R143 |
T297 |
T295 |
amod |
intestinal,phenotype |
| R151 |
T309 |
T308 |
amod |
mixed,background |
| R152 |
T310 |
T308 |
amod |
genetic,background |
| R155 |
T313 |
T312 |
nummod |
95,C57Bl |
| R156 |
T314 |
T313 |
quantmod |
%,95 |
| R162 |
T320 |
T318 |
quantmod |
%,5 |
| R172 |
T330 |
T329 |
nmod |
C57Bl,background |
| R173 |
T331 |
T330 |
punct |
/,C57Bl |
| R174 |
T332 |
T330 |
nummod |
6,C57Bl |
| R181 |
T339 |
T338 |
amod |
intestinal,phenotype |
| R182 |
T340 |
T338 |
compound |
CF,phenotype |
| R189 |
T349 |
T348 |
amod |
mixed,background |
| R197 |
T357 |
T356 |
compound |
mouse,chow |
| R202 |
T362 |
T361 |
amod |
intestinal,inflammation |
| R208 |
T368 |
T367 |
compound |
RT,PCR |
| R209 |
T369 |
T367 |
punct |
-,PCR |
| R218 |
T378 |
T379 |
compound |
body,weight |
| R219 |
T379 |
T377 |
compound |
weight,gain |
| R225 |
T385 |
T384 |
compound |
mucus,accumulation |
| R229 |
T389 |
T388 |
amod |
intestinal,crypts |
| R238 |
T400 |
T399 |
compound |
gender,effect |
| R242 |
T404 |
T403 |
compound |
weight,gain |
| R249 |
T411 |
T410 |
amod |
significant,improvement |
| R267 |
T429 |
T428 |
nsubj |
females,showed |
| R273 |
T435 |
T433 |
cc |
and,4 |