PMC:1140370 / 35353-35968
Annnotations
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11122 | 0-2 | IN | denotes | On |
T11123 | 82-90 | VBD | denotes | restored |
T11124 | 3-4 | NN | denotes | Y |
T11125 | 5-9 | NN | denotes | fork |
T11126 | 4-5 | HYPH | denotes | - |
T11127 | 10-20 | NNS | denotes | substrates |
T11128 | 20-22 | , | denotes | , |
T11129 | 22-30 | NN | denotes | increase |
T11130 | 31-33 | IN | denotes | of |
T11131 | 34-36 | NN | denotes | AT |
T11132 | 42-47 | NNS | denotes | pairs |
T11133 | 37-41 | NN | denotes | base |
T11134 | 48-50 | IN | denotes | in |
T11135 | 51-54 | DT | denotes | the |
T11136 | 55-61 | NN | denotes | duplex |
T11137 | 62-63 | -LRB- | denotes | ( |
T11138 | 66-73 | NNS | denotes | repeats |
T11139 | 63-65 | CD | denotes | 10 |
T11140 | 74-76 | IN | denotes | of |
T11141 | 77-80 | NN | denotes | CTT |
T11142 | 80-81 | -RRB- | denotes | ) |
T11143 | 91-94 | DT | denotes | the |
T11144 | 95-104 | NN | denotes | unwinding |
T11145 | 104-105 | . | denotes | . |
T11146 | 105-293 | sentence | denotes | These results indicate either that thymine residues are required on the duplex DNA for continuous unwinding, or that Mcm4/6/7 is simply not efficient enough to unwind the stable GC pairs. |
T11147 | 106-111 | DT | denotes | These |
T11148 | 112-119 | NNS | denotes | results |
T11149 | 120-128 | VBP | denotes | indicate |
T11150 | 129-135 | CC | denotes | either |
T11151 | 162-170 | VBN | denotes | required |
T11152 | 136-140 | IN | denotes | that |
T11153 | 141-148 | NN | denotes | thymine |
T11154 | 149-157 | NNS | denotes | residues |
T11155 | 158-161 | VBP | denotes | are |
T11156 | 171-173 | IN | denotes | on |
T11157 | 174-177 | DT | denotes | the |
T11158 | 185-188 | NN | denotes | DNA |
T11159 | 178-184 | NN | denotes | duplex |
T11160 | 189-192 | IN | denotes | for |
T11161 | 193-203 | JJ | denotes | continuous |
T11162 | 204-213 | NN | denotes | unwinding |
T11163 | 213-215 | , | denotes | , |
T11164 | 215-217 | CC | denotes | or |
T11165 | 218-222 | IN | denotes | that |
T11166 | 232-234 | VBZ | denotes | is |
T11167 | 223-227 | NN | denotes | Mcm4 |
T11168 | 227-228 | HYPH | denotes | / |
T11169 | 228-229 | CD | denotes | 6 |
T11170 | 229-230 | HYPH | denotes | / |
T11171 | 230-231 | CD | denotes | 7 |
T11172 | 235-241 | RB | denotes | simply |
T11173 | 242-245 | RB | denotes | not |
T11174 | 246-255 | JJ | denotes | efficient |
T11175 | 256-262 | RB | denotes | enough |
T11176 | 263-265 | TO | denotes | to |
T11177 | 266-272 | VB | denotes | unwind |
T11178 | 273-276 | DT | denotes | the |
T11179 | 287-292 | NNS | denotes | pairs |
T11180 | 277-283 | JJ | denotes | stable |
T11181 | 284-286 | NN | denotes | GC |
T11182 | 292-293 | . | denotes | . |
T11183 | 293-615 | sentence | denotes | Replacement of the central guanosine with inosine in the CGG repeat duplex DNA resulted in displacement (Figure 8E) (31), suggesting that the continuous presence of AT base pair may not be essential for the Mcm helicase function and that the thermostability of GC base pairs is inhibitory for helicase action of Mcm4/6/7. |
T11184 | 294-305 | NN | denotes | Replacement |
T11185 | 373-381 | VBD | denotes | resulted |
T11186 | 306-308 | IN | denotes | of |
T11187 | 309-312 | DT | denotes | the |
T11188 | 321-330 | NN | denotes | guanosine |
T11189 | 313-320 | JJ | denotes | central |
T11190 | 331-335 | IN | denotes | with |
T11191 | 336-343 | NN | denotes | inosine |
T11192 | 344-346 | IN | denotes | in |
T11193 | 347-350 | DT | denotes | the |
T11194 | 369-372 | NN | denotes | DNA |
T11195 | 351-354 | NN | denotes | CGG |
T11196 | 355-361 | NN | denotes | repeat |
T11197 | 362-368 | NN | denotes | duplex |
T11198 | 382-384 | IN | denotes | in |
T11199 | 385-397 | NN | denotes | displacement |
T11200 | 398-399 | -LRB- | denotes | ( |
T11201 | 406-408 | NN | denotes | 8E |
T11202 | 399-405 | NN | denotes | Figure |
T11203 | 408-409 | -RRB- | denotes | ) |
T11204 | 410-411 | -LRB- | denotes | ( |
T11205 | 411-413 | CD | denotes | 31 |
T11206 | 413-414 | -RRB- | denotes | ) |
T11207 | 414-416 | , | denotes | , |
T11208 | 416-426 | VBG | denotes | suggesting |
T11209 | 427-431 | IN | denotes | that |
T11210 | 480-482 | VB | denotes | be |
T11211 | 432-435 | DT | denotes | the |
T11212 | 447-455 | NN | denotes | presence |
T11213 | 436-446 | JJ | denotes | continuous |
T11214 | 456-458 | IN | denotes | of |
T11215 | 459-461 | NN | denotes | AT |
T11216 | 467-471 | NN | denotes | pair |
T11217 | 462-466 | NN | denotes | base |
T11218 | 472-475 | MD | denotes | may |
T11219 | 476-479 | RB | denotes | not |
T11220 | 483-492 | JJ | denotes | essential |
T11221 | 493-496 | IN | denotes | for |
T11222 | 497-500 | DT | denotes | the |
T11223 | 514-522 | NN | denotes | function |
T11224 | 501-504 | NN | denotes | Mcm |
T11225 | 505-513 | NN | denotes | helicase |
T11226 | 523-526 | CC | denotes | and |
T11227 | 527-531 | IN | denotes | that |
T11228 | 569-571 | VBZ | denotes | is |
T11229 | 532-535 | DT | denotes | the |
T11230 | 536-551 | NN | denotes | thermostability |
T11231 | 552-554 | IN | denotes | of |
T11232 | 555-557 | NN | denotes | GC |
T11233 | 563-568 | NNS | denotes | pairs |
T11234 | 558-562 | NN | denotes | base |
T11235 | 572-582 | JJ | denotes | inhibitory |
T11236 | 583-586 | IN | denotes | for |
T11237 | 587-595 | NN | denotes | helicase |
T11238 | 596-602 | NN | denotes | action |
T11239 | 603-605 | IN | denotes | of |
T11240 | 606-610 | NN | denotes | Mcm4 |
T11241 | 610-611 | HYPH | denotes | / |
T11242 | 611-612 | CD | denotes | 6 |
T11243 | 612-613 | HYPH | denotes | / |
T11244 | 613-614 | CD | denotes | 7 |
T11245 | 614-615 | . | denotes | . |
R7316 | T11122 | T11123 | prep | On,restored |
R7317 | T11124 | T11125 | compound | Y,fork |
R7318 | T11125 | T11127 | compound | fork,substrates |
R7319 | T11126 | T11125 | punct | -,fork |
R7320 | T11127 | T11122 | pobj | substrates,On |
R7321 | T11128 | T11123 | punct | ", ",restored |
R7322 | T11129 | T11123 | nsubj | increase,restored |
R7323 | T11130 | T11129 | prep | of,increase |
R7324 | T11131 | T11132 | compound | AT,pairs |
R7325 | T11132 | T11130 | pobj | pairs,of |
R7326 | T11133 | T11132 | compound | base,pairs |
R7327 | T11134 | T11129 | prep | in,increase |
R7328 | T11135 | T11136 | det | the,duplex |
R7329 | T11136 | T11134 | pobj | duplex,in |
R7330 | T11137 | T11138 | punct | (,repeats |
R7331 | T11138 | T11136 | parataxis | repeats,duplex |
R7332 | T11139 | T11138 | nummod | 10,repeats |
R7333 | T11140 | T11138 | prep | of,repeats |
R7334 | T11141 | T11140 | pobj | CTT,of |
R7335 | T11142 | T11138 | punct | ),repeats |
R7336 | T11143 | T11144 | det | the,unwinding |
R7337 | T11144 | T11123 | dobj | unwinding,restored |
R7338 | T11145 | T11123 | punct | .,restored |
R7339 | T11147 | T11148 | det | These,results |
R7340 | T11148 | T11149 | nsubj | results,indicate |
R7341 | T11150 | T11151 | preconj | either,required |
R7342 | T11151 | T11149 | advcl | required,indicate |
R7343 | T11152 | T11151 | mark | that,required |
R7344 | T11153 | T11154 | compound | thymine,residues |
R7345 | T11154 | T11151 | nsubjpass | residues,required |
R7346 | T11155 | T11151 | auxpass | are,required |
R7347 | T11156 | T11151 | prep | on,required |
R7348 | T11157 | T11158 | det | the,DNA |
R7349 | T11158 | T11156 | pobj | DNA,on |
R7350 | T11159 | T11158 | compound | duplex,DNA |
R7351 | T11160 | T11151 | prep | for,required |
R7352 | T11161 | T11162 | amod | continuous,unwinding |
R7353 | T11162 | T11160 | pobj | unwinding,for |
R7354 | T11163 | T11151 | punct | ", ",required |
R7355 | T11164 | T11151 | cc | or,required |
R7356 | T11165 | T11166 | mark | that,is |
R7357 | T11166 | T11151 | conj | is,required |
R7358 | T11167 | T11166 | nsubj | Mcm4,is |
R7359 | T11168 | T11167 | punct | /,Mcm4 |
R7360 | T11169 | T11167 | nummod | 6,Mcm4 |
R7361 | T11170 | T11167 | punct | /,Mcm4 |
R7362 | T11171 | T11167 | nummod | 7,Mcm4 |
R7363 | T11172 | T11166 | advmod | simply,is |
R7364 | T11173 | T11166 | neg | not,is |
R7365 | T11174 | T11166 | acomp | efficient,is |
R7366 | T11175 | T11174 | advmod | enough,efficient |
R7367 | T11176 | T11177 | aux | to,unwind |
R7368 | T11177 | T11174 | xcomp | unwind,efficient |
R7369 | T11178 | T11179 | det | the,pairs |
R7370 | T11179 | T11177 | dobj | pairs,unwind |
R7371 | T11180 | T11179 | amod | stable,pairs |
R7372 | T11181 | T11179 | compound | GC,pairs |
R7373 | T11182 | T11149 | punct | .,indicate |
R7374 | T11184 | T11185 | nsubj | Replacement,resulted |
R7375 | T11186 | T11184 | prep | of,Replacement |
R7376 | T11187 | T11188 | det | the,guanosine |
R7377 | T11188 | T11186 | pobj | guanosine,of |
R7378 | T11189 | T11188 | amod | central,guanosine |
R7379 | T11190 | T11184 | prep | with,Replacement |
R7380 | T11191 | T11190 | pobj | inosine,with |
R7381 | T11192 | T11184 | prep | in,Replacement |
R7382 | T11193 | T11194 | det | the,DNA |
R7383 | T11194 | T11192 | pobj | DNA,in |
R7384 | T11195 | T11196 | compound | CGG,repeat |
R7385 | T11196 | T11194 | compound | repeat,DNA |
R7386 | T11197 | T11194 | compound | duplex,DNA |
R7387 | T11198 | T11185 | prep | in,resulted |
R7388 | T11199 | T11198 | pobj | displacement,in |
R7389 | T11200 | T11201 | punct | (,8E |
R7390 | T11201 | T11185 | parataxis | 8E,resulted |
R7391 | T11202 | T11201 | compound | Figure,8E |
R7392 | T11203 | T11201 | punct | ),8E |
R7393 | T11204 | T11205 | punct | (,31 |
R7394 | T11205 | T11185 | parataxis | 31,resulted |
R7395 | T11206 | T11205 | punct | ),31 |
R7396 | T11207 | T11185 | punct | ", ",resulted |
R7397 | T11208 | T11185 | advcl | suggesting,resulted |
R7398 | T11209 | T11210 | mark | that,be |
R7399 | T11210 | T11208 | advcl | be,suggesting |
R7400 | T11211 | T11212 | det | the,presence |
R7401 | T11212 | T11210 | nsubj | presence,be |
R7402 | T11213 | T11212 | amod | continuous,presence |
R7403 | T11214 | T11212 | prep | of,presence |
R7404 | T11215 | T11216 | compound | AT,pair |
R7405 | T11216 | T11214 | pobj | pair,of |
R7406 | T11217 | T11216 | compound | base,pair |
R7407 | T11218 | T11210 | aux | may,be |
R7408 | T11219 | T11210 | neg | not,be |
R7409 | T11220 | T11210 | acomp | essential,be |
R7410 | T11221 | T11220 | prep | for,essential |
R7411 | T11222 | T11223 | det | the,function |
R7412 | T11223 | T11221 | pobj | function,for |
R7413 | T11224 | T11225 | compound | Mcm,helicase |
R7414 | T11225 | T11223 | compound | helicase,function |
R7415 | T11226 | T11210 | cc | and,be |
R7416 | T11227 | T11228 | mark | that,is |
R7417 | T11228 | T11210 | conj | is,be |
R7418 | T11229 | T11230 | det | the,thermostability |
R7419 | T11230 | T11228 | nsubj | thermostability,is |
R7420 | T11231 | T11230 | prep | of,thermostability |
R7421 | T11232 | T11233 | compound | GC,pairs |
R7422 | T11233 | T11231 | pobj | pairs,of |
R7423 | T11234 | T11233 | compound | base,pairs |
R7424 | T11235 | T11228 | acomp | inhibitory,is |
R7425 | T11236 | T11235 | prep | for,inhibitory |
R7426 | T11237 | T11238 | compound | helicase,action |
R7427 | T11238 | T11236 | pobj | action,for |
R7428 | T11239 | T11238 | prep | of,action |
R7429 | T11240 | T11239 | pobj | Mcm4,of |
R7430 | T11241 | T11240 | punct | /,Mcm4 |
R7431 | T11242 | T11240 | nummod | 6,Mcm4 |
R7432 | T11243 | T11240 | punct | /,Mcm4 |
R7433 | T11244 | T11240 | nummod | 7,Mcm4 |
R7434 | T11245 | T11185 | punct | .,resulted |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the bag model. You can change it to the chain model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10754 | 5-9 | GO:0005657 | denotes | fork |
T10755 | 37-41 | CHEBI_SO_EXT:base | denotes | base |
T10756 | 37-47 | SO_EXT:0000028 | denotes | base pairs |
T10757 | 66-73 | SO_EXT:sequence_repeat_unit_or_region | denotes | repeats |
T10758 | 141-148 | CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | thymine |
T10759 | 149-157 | CHEBI_EXT:residue | denotes | residues |
T10760 | 178-188 | CHEBI_SO_EXT:double_stranded_DNA | denotes | duplex DNA |
T10761 | 223-227 | PR_EXT:000010246 | denotes | Mcm4 |
T10762 | 223-231 | GO:0097373 | denotes | Mcm4/6/7 |
T10763 | 287-292 | SO_EXT:0000028 | denotes | pairs |
T10764 | 294-305 | SO_EXT:sequence_substitution_entity_or_process | denotes | Replacement |
T10765 | 321-330 | CHEBI_EXT:guanine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | guanosine |
T10766 | 336-343 | CHEBI_SO_EXT:inosine | denotes | inosine |
T10767 | 355-361 | SO_EXT:sequence_repeat_unit_or_region | denotes | repeat |
T10768 | 362-372 | CHEBI_SO_EXT:double_stranded_DNA | denotes | duplex DNA |
T10769 | 462-466 | CHEBI_SO_EXT:base | denotes | base |
T10770 | 462-471 | SO_EXT:0000028 | denotes | base pair |
T10771 | 501-504 | GO:0042555 | denotes | Mcm |
T10772 | 505-513 | GO_EXT:0004386 | denotes | helicase |
T10773 | 558-562 | CHEBI_SO_EXT:base | denotes | base |
T10774 | 558-568 | SO_EXT:0000028 | denotes | base pairs |
T10775 | 587-595 | GO_EXT:0004386 | denotes | helicase |
T10776 | 606-610 | PR_EXT:000010246 | denotes | Mcm4 |
T10777 | 606-614 | GO:0097373 | denotes | Mcm4/6/7 |
craft-ca-core-dev
Below, discontinuous spans are shown in the bag model. You can change it to the chain model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10650 | 5-9 | GO:0005657 | denotes | fork |
T10651 | 37-47 | SO:0000028 | denotes | base pairs |
T10652 | 178-184 | SO:0000985 | denotes | duplex |
T10653 | 223-227 | PR:000010246 | denotes | Mcm4 |
T10654 | 223-231 | GO:0097373 | denotes | Mcm4/6/7 |
T10655 | 287-292 | SO:0000028 | denotes | pairs |
T10656 | 362-368 | SO:0000985 | denotes | duplex |
T10657 | 462-471 | SO:0000028 | denotes | base pair |
T10658 | 501-504 | GO:0042555 | denotes | Mcm |
T10659 | 558-568 | SO:0000028 | denotes | base pairs |
T10660 | 606-610 | PR:000010246 | denotes | Mcm4 |
T10661 | 606-614 | GO:0097373 | denotes | Mcm4/6/7 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
15917436-4080553-76775545 | 411-413 | 4080553 | denotes | 31 |