![Logo](/assets/logo-d3f1fdf60522f0983e71f9fcc720cb7da5b55c0b748ed5bded3d2fbf81387bf0.png)
PMC:1140370 / 32645-34053
Annnotations
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10242 | 0-2 | PRP | denotes | We |
T10243 | 8-16 | VBN | denotes | examined |
T10244 | 3-7 | VBP | denotes | have |
T10245 | 17-19 | IN | denotes | in |
T10246 | 20-26 | NN | denotes | detail |
T10247 | 27-30 | DT | denotes | the |
T10248 | 31-37 | NN | denotes | effect |
T10249 | 38-40 | IN | denotes | of |
T10250 | 41-49 | NN | denotes | sequence |
T10251 | 50-57 | NN | denotes | context |
T10252 | 58-60 | IN | denotes | of |
T10253 | 61-64 | DT | denotes | the |
T10254 | 81-84 | NN | denotes | DNA |
T10255 | 65-71 | JJ | denotes | single |
T10256 | 72-80 | VBN | denotes | stranded |
T10257 | 71-72 | HYPH | denotes | - |
T10258 | 85-87 | IN | denotes | on |
T10259 | 88-91 | DT | denotes | the |
T10260 | 101-109 | NN | denotes | activity |
T10261 | 92-100 | NN | denotes | helicase |
T10262 | 110-112 | IN | denotes | of |
T10263 | 113-116 | NN | denotes | Mcm |
T10264 | 116-117 | . | denotes | . |
T10265 | 117-215 | sentence | denotes | The results indicate that thymine content of 50% is sufficient for the maximum helicase activity. |
T10266 | 118-121 | DT | denotes | The |
T10267 | 122-129 | NNS | denotes | results |
T10268 | 130-138 | VBP | denotes | indicate |
T10269 | 139-143 | IN | denotes | that |
T10270 | 167-169 | VBZ | denotes | is |
T10271 | 144-151 | NN | denotes | thymine |
T10272 | 152-159 | NN | denotes | content |
T10273 | 160-162 | IN | denotes | of |
T10274 | 163-165 | CD | denotes | 50 |
T10275 | 165-166 | NN | denotes | % |
T10276 | 170-180 | JJ | denotes | sufficient |
T10277 | 181-184 | IN | denotes | for |
T10278 | 185-188 | DT | denotes | the |
T10279 | 206-214 | NN | denotes | activity |
T10280 | 189-196 | JJ | denotes | maximum |
T10281 | 197-205 | NN | denotes | helicase |
T10282 | 214-215 | . | denotes | . |
T10283 | 215-321 | sentence | denotes | The efficiency of displacement decreased as the thymine content of the 3′-tail dropped to 33% (Figure 6). |
T10284 | 216-219 | DT | denotes | The |
T10285 | 220-230 | NN | denotes | efficiency |
T10286 | 247-256 | VBD | denotes | decreased |
T10287 | 231-233 | IN | denotes | of |
T10288 | 234-246 | NN | denotes | displacement |
T10289 | 257-259 | IN | denotes | as |
T10290 | 295-302 | VBD | denotes | dropped |
T10291 | 260-263 | DT | denotes | the |
T10292 | 272-279 | NN | denotes | content |
T10293 | 264-271 | NN | denotes | thymine |
T10294 | 280-282 | IN | denotes | of |
T10295 | 283-286 | DT | denotes | the |
T10296 | 290-294 | NN | denotes | tail |
T10297 | 287-288 | CD | denotes | 3 |
T10298 | 288-289 | SYM | denotes | ′ |
T10299 | 289-290 | HYPH | denotes | - |
T10300 | 303-305 | IN | denotes | to |
T10301 | 306-308 | CD | denotes | 33 |
T10302 | 308-309 | NN | denotes | % |
T10303 | 310-311 | -LRB- | denotes | ( |
T10304 | 311-317 | NN | denotes | Figure |
T10305 | 318-319 | CD | denotes | 6 |
T10306 | 319-320 | -RRB- | denotes | ) |
T10307 | 320-321 | . | denotes | . |
T10308 | 321-465 | sentence | denotes | The stretches of thymine residues may not be necessarily required, since repeats of TC dinucleotides served as a potent activator for Mcm4/6/7. |
T10309 | 322-325 | DT | denotes | The |
T10310 | 326-335 | NNS | denotes | stretches |
T10311 | 379-387 | VBN | denotes | required |
T10312 | 336-338 | IN | denotes | of |
T10313 | 339-346 | NN | denotes | thymine |
T10314 | 347-355 | NNS | denotes | residues |
T10315 | 356-359 | MD | denotes | may |
T10316 | 360-363 | RB | denotes | not |
T10317 | 364-366 | VB | denotes | be |
T10318 | 367-378 | RB | denotes | necessarily |
T10319 | 387-389 | , | denotes | , |
T10320 | 389-394 | IN | denotes | since |
T10321 | 423-429 | VBD | denotes | served |
T10322 | 395-402 | NNS | denotes | repeats |
T10323 | 403-405 | IN | denotes | of |
T10324 | 406-408 | NN | denotes | TC |
T10325 | 409-422 | NNS | denotes | dinucleotides |
T10326 | 430-432 | IN | denotes | as |
T10327 | 433-434 | DT | denotes | a |
T10328 | 442-451 | NN | denotes | activator |
T10329 | 435-441 | JJ | denotes | potent |
T10330 | 452-455 | IN | denotes | for |
T10331 | 456-460 | NN | denotes | Mcm4 |
T10332 | 460-461 | HYPH | denotes | / |
T10333 | 461-462 | CD | denotes | 6 |
T10334 | 462-463 | HYPH | denotes | / |
T10335 | 463-464 | CD | denotes | 7 |
T10336 | 464-465 | . | denotes | . |
T10337 | 465-590 | sentence | denotes | We also noticed that the presence of a secondary structure within the single-stranded DNA is inhibitory for helicase action. |
T10338 | 466-468 | PRP | denotes | We |
T10339 | 474-481 | VBD | denotes | noticed |
T10340 | 469-473 | RB | denotes | also |
T10341 | 482-486 | IN | denotes | that |
T10342 | 556-558 | VBZ | denotes | is |
T10343 | 487-490 | DT | denotes | the |
T10344 | 491-499 | NN | denotes | presence |
T10345 | 500-502 | IN | denotes | of |
T10346 | 503-504 | DT | denotes | a |
T10347 | 515-524 | NN | denotes | structure |
T10348 | 505-514 | JJ | denotes | secondary |
T10349 | 525-531 | IN | denotes | within |
T10350 | 532-535 | DT | denotes | the |
T10351 | 552-555 | NN | denotes | DNA |
T10352 | 536-542 | JJ | denotes | single |
T10353 | 543-551 | VBN | denotes | stranded |
T10354 | 542-543 | HYPH | denotes | - |
T10355 | 559-569 | JJ | denotes | inhibitory |
T10356 | 570-573 | IN | denotes | for |
T10357 | 574-582 | NN | denotes | helicase |
T10358 | 583-589 | NN | denotes | action |
T10359 | 589-590 | . | denotes | . |
T10360 | 590-702 | sentence | denotes | Nuclease footprinting assays indicated that binding was interfered by the secondary structure (data not shown). |
T10361 | 591-599 | NN | denotes | Nuclease |
T10362 | 600-612 | NN | denotes | footprinting |
T10363 | 613-619 | NNS | denotes | assays |
T10364 | 620-629 | VBD | denotes | indicated |
T10365 | 630-634 | IN | denotes | that |
T10366 | 647-657 | VBN | denotes | interfered |
T10367 | 635-642 | NN | denotes | binding |
T10368 | 643-646 | VBD | denotes | was |
T10369 | 658-660 | IN | denotes | by |
T10370 | 661-664 | DT | denotes | the |
T10371 | 675-684 | NN | denotes | structure |
T10372 | 665-674 | JJ | denotes | secondary |
T10373 | 685-686 | -LRB- | denotes | ( |
T10374 | 695-700 | VBN | denotes | shown |
T10375 | 686-690 | NNS | denotes | data |
T10376 | 691-694 | RB | denotes | not |
T10377 | 700-701 | -RRB- | denotes | ) |
T10378 | 701-702 | . | denotes | . |
T10379 | 702-1110 | sentence | denotes | Thus, we have concluded that Mcm4/6/7 helicase is most efficiently activated by non-structured single-stranded DNA with thymine content of 50% or more, although significant stimulation is observed also by DNA with less thymine content (Figure 7), suggesting that the sequence specificity for Mcm helicase activation is rather relaxed and that the extent of the activation may depend on the sequence context. |
T10380 | 703-707 | RB | denotes | Thus |
T10381 | 717-726 | VBN | denotes | concluded |
T10382 | 707-709 | , | denotes | , |
T10383 | 709-711 | PRP | denotes | we |
T10384 | 712-716 | VBP | denotes | have |
T10385 | 727-731 | IN | denotes | that |
T10386 | 770-779 | VBN | denotes | activated |
T10387 | 732-736 | NN | denotes | Mcm4 |
T10388 | 741-749 | NN | denotes | helicase |
T10389 | 736-737 | HYPH | denotes | / |
T10390 | 737-738 | CD | denotes | 6 |
T10391 | 738-739 | HYPH | denotes | / |
T10392 | 739-740 | CD | denotes | 7 |
T10393 | 750-752 | VBZ | denotes | is |
T10394 | 753-757 | RBS | denotes | most |
T10395 | 758-769 | RB | denotes | efficiently |
T10396 | 780-782 | IN | denotes | by |
T10397 | 783-797 | JJ | denotes | non-structured |
T10398 | 814-817 | NN | denotes | DNA |
T10399 | 798-804 | JJ | denotes | single |
T10400 | 805-813 | VBN | denotes | stranded |
T10401 | 804-805 | HYPH | denotes | - |
T10402 | 818-822 | IN | denotes | with |
T10403 | 823-830 | NN | denotes | thymine |
T10404 | 831-838 | NN | denotes | content |
T10405 | 839-841 | IN | denotes | of |
T10406 | 842-844 | CD | denotes | 50 |
T10407 | 844-845 | NN | denotes | % |
T10408 | 846-848 | CC | denotes | or |
T10409 | 849-853 | JJR | denotes | more |
T10410 | 853-855 | , | denotes | , |
T10411 | 855-863 | IN | denotes | although |
T10412 | 891-899 | VBN | denotes | observed |
T10413 | 864-875 | JJ | denotes | significant |
T10414 | 876-887 | NN | denotes | stimulation |
T10415 | 888-890 | VBZ | denotes | is |
T10416 | 900-904 | RB | denotes | also |
T10417 | 905-907 | IN | denotes | by |
T10418 | 908-911 | NN | denotes | DNA |
T10419 | 912-916 | IN | denotes | with |
T10420 | 917-921 | JJR | denotes | less |
T10421 | 930-937 | NN | denotes | content |
T10422 | 922-929 | NN | denotes | thymine |
T10423 | 938-939 | -LRB- | denotes | ( |
T10424 | 939-945 | NN | denotes | Figure |
T10425 | 946-947 | CD | denotes | 7 |
T10426 | 947-948 | -RRB- | denotes | ) |
T10427 | 948-950 | , | denotes | , |
T10428 | 950-960 | VBG | denotes | suggesting |
T10429 | 961-965 | IN | denotes | that |
T10430 | 1019-1021 | VBZ | denotes | is |
T10431 | 966-969 | DT | denotes | the |
T10432 | 979-990 | NN | denotes | specificity |
T10433 | 970-978 | NN | denotes | sequence |
T10434 | 991-994 | IN | denotes | for |
T10435 | 995-998 | NN | denotes | Mcm |
T10436 | 999-1007 | NN | denotes | helicase |
T10437 | 1008-1018 | NN | denotes | activation |
T10438 | 1022-1028 | RB | denotes | rather |
T10439 | 1029-1036 | JJ | denotes | relaxed |
T10440 | 1037-1040 | CC | denotes | and |
T10441 | 1041-1045 | IN | denotes | that |
T10442 | 1079-1085 | VB | denotes | depend |
T10443 | 1046-1049 | DT | denotes | the |
T10444 | 1050-1056 | NN | denotes | extent |
T10445 | 1057-1059 | IN | denotes | of |
T10446 | 1060-1063 | DT | denotes | the |
T10447 | 1064-1074 | NN | denotes | activation |
T10448 | 1075-1078 | MD | denotes | may |
T10449 | 1086-1088 | IN | denotes | on |
T10450 | 1089-1092 | DT | denotes | the |
T10451 | 1102-1109 | NN | denotes | context |
T10452 | 1093-1101 | NN | denotes | sequence |
T10453 | 1109-1110 | . | denotes | . |
T10454 | 1110-1408 | sentence | denotes | This would be reasonable given the flexibility and differential regulation of site selection for initiation of DNA replication during development or in various cell types, as well as the variability in initiation potential of each replication origin on the genome even within the single cell type. |
T10455 | 1111-1115 | DT | denotes | This |
T10456 | 1122-1124 | VB | denotes | be |
T10457 | 1116-1121 | MD | denotes | would |
T10458 | 1125-1135 | JJ | denotes | reasonable |
T10459 | 1136-1141 | VBN | denotes | given |
T10460 | 1142-1145 | DT | denotes | the |
T10461 | 1146-1157 | NN | denotes | flexibility |
T10462 | 1158-1161 | CC | denotes | and |
T10463 | 1162-1174 | JJ | denotes | differential |
T10464 | 1175-1185 | NN | denotes | regulation |
T10465 | 1186-1188 | IN | denotes | of |
T10466 | 1189-1193 | NN | denotes | site |
T10467 | 1194-1203 | NN | denotes | selection |
T10468 | 1204-1207 | IN | denotes | for |
T10469 | 1208-1218 | NN | denotes | initiation |
T10470 | 1219-1221 | IN | denotes | of |
T10471 | 1222-1225 | NN | denotes | DNA |
T10472 | 1226-1237 | NN | denotes | replication |
T10473 | 1238-1244 | IN | denotes | during |
T10474 | 1245-1256 | NN | denotes | development |
T10475 | 1257-1259 | CC | denotes | or |
T10476 | 1260-1262 | IN | denotes | in |
T10477 | 1263-1270 | JJ | denotes | various |
T10478 | 1276-1281 | NNS | denotes | types |
T10479 | 1271-1275 | NN | denotes | cell |
T10480 | 1281-1283 | , | denotes | , |
T10481 | 1283-1285 | RB | denotes | as |
T10482 | 1291-1293 | IN | denotes | as |
T10483 | 1286-1290 | RB | denotes | well |
T10484 | 1294-1297 | DT | denotes | the |
T10485 | 1298-1309 | NN | denotes | variability |
T10486 | 1310-1312 | IN | denotes | in |
T10487 | 1313-1323 | NN | denotes | initiation |
T10488 | 1324-1333 | NN | denotes | potential |
T10489 | 1334-1336 | IN | denotes | of |
T10490 | 1337-1341 | DT | denotes | each |
T10491 | 1354-1360 | NN | denotes | origin |
T10492 | 1342-1353 | NN | denotes | replication |
T10493 | 1361-1363 | IN | denotes | on |
T10494 | 1364-1367 | DT | denotes | the |
T10495 | 1368-1374 | NN | denotes | genome |
T10496 | 1375-1379 | RB | denotes | even |
T10497 | 1380-1386 | IN | denotes | within |
T10498 | 1387-1390 | DT | denotes | the |
T10499 | 1403-1407 | NN | denotes | type |
T10500 | 1391-1397 | JJ | denotes | single |
T10501 | 1398-1402 | NN | denotes | cell |
T10502 | 1407-1408 | . | denotes | . |
R6819 | T10242 | T10243 | nsubj | We,examined |
R6820 | T10244 | T10243 | aux | have,examined |
R6821 | T10245 | T10243 | prep | in,examined |
R6822 | T10246 | T10245 | pobj | detail,in |
R6823 | T10247 | T10248 | det | the,effect |
R6824 | T10248 | T10243 | dobj | effect,examined |
R6825 | T10249 | T10248 | prep | of,effect |
R6826 | T10250 | T10251 | compound | sequence,context |
R6827 | T10251 | T10249 | pobj | context,of |
R6828 | T10252 | T10251 | prep | of,context |
R6829 | T10253 | T10254 | det | the,DNA |
R6830 | T10254 | T10252 | pobj | DNA,of |
R6831 | T10255 | T10256 | amod | single,stranded |
R6832 | T10256 | T10254 | amod | stranded,DNA |
R6833 | T10257 | T10256 | punct | -,stranded |
R6834 | T10258 | T10248 | prep | on,effect |
R6835 | T10259 | T10260 | det | the,activity |
R6836 | T10260 | T10258 | pobj | activity,on |
R6837 | T10261 | T10260 | compound | helicase,activity |
R6838 | T10262 | T10260 | prep | of,activity |
R6839 | T10263 | T10262 | pobj | Mcm,of |
R6840 | T10264 | T10243 | punct | .,examined |
R6841 | T10266 | T10267 | det | The,results |
R6842 | T10267 | T10268 | nsubj | results,indicate |
R6843 | T10269 | T10270 | mark | that,is |
R6844 | T10270 | T10268 | ccomp | is,indicate |
R6845 | T10271 | T10272 | compound | thymine,content |
R6846 | T10272 | T10270 | nsubj | content,is |
R6847 | T10273 | T10272 | prep | of,content |
R6848 | T10274 | T10275 | nummod | 50,% |
R6849 | T10275 | T10273 | pobj | %,of |
R6850 | T10276 | T10270 | acomp | sufficient,is |
R6851 | T10277 | T10276 | prep | for,sufficient |
R6852 | T10278 | T10279 | det | the,activity |
R6853 | T10279 | T10277 | pobj | activity,for |
R6854 | T10280 | T10279 | amod | maximum,activity |
R6855 | T10281 | T10279 | compound | helicase,activity |
R6856 | T10282 | T10268 | punct | .,indicate |
R6857 | T10284 | T10285 | det | The,efficiency |
R6858 | T10285 | T10286 | nsubj | efficiency,decreased |
R6859 | T10287 | T10285 | prep | of,efficiency |
R6860 | T10288 | T10287 | pobj | displacement,of |
R6861 | T10289 | T10290 | mark | as,dropped |
R6862 | T10290 | T10286 | advcl | dropped,decreased |
R6863 | T10291 | T10292 | det | the,content |
R6864 | T10292 | T10290 | nsubj | content,dropped |
R6865 | T10293 | T10292 | compound | thymine,content |
R6866 | T10294 | T10292 | prep | of,content |
R6867 | T10295 | T10296 | det | the,tail |
R6868 | T10296 | T10294 | pobj | tail,of |
R6869 | T10297 | T10296 | nummod | 3,tail |
R6870 | T10298 | T10297 | punct | ′,3 |
R6871 | T10299 | T10296 | punct | -,tail |
R6872 | T10300 | T10290 | prep | to,dropped |
R6873 | T10301 | T10302 | nummod | 33,% |
R6874 | T10302 | T10300 | pobj | %,to |
R6875 | T10303 | T10304 | punct | (,Figure |
R6876 | T10304 | T10290 | parataxis | Figure,dropped |
R6877 | T10305 | T10304 | nummod | 6,Figure |
R6878 | T10306 | T10304 | punct | ),Figure |
R6879 | T10307 | T10286 | punct | .,decreased |
R6880 | T10309 | T10310 | det | The,stretches |
R6881 | T10310 | T10311 | nsubjpass | stretches,required |
R6882 | T10312 | T10310 | prep | of,stretches |
R6883 | T10313 | T10314 | compound | thymine,residues |
R6884 | T10314 | T10312 | pobj | residues,of |
R6885 | T10315 | T10311 | aux | may,required |
R6886 | T10316 | T10311 | neg | not,required |
R6887 | T10317 | T10311 | auxpass | be,required |
R6888 | T10318 | T10311 | advmod | necessarily,required |
R6889 | T10319 | T10311 | punct | ", ",required |
R6890 | T10320 | T10321 | mark | since,served |
R6891 | T10321 | T10311 | advcl | served,required |
R6892 | T10322 | T10321 | nsubj | repeats,served |
R6893 | T10323 | T10322 | prep | of,repeats |
R6894 | T10324 | T10325 | compound | TC,dinucleotides |
R6895 | T10325 | T10323 | pobj | dinucleotides,of |
R6896 | T10326 | T10321 | prep | as,served |
R6897 | T10327 | T10328 | det | a,activator |
R6898 | T10328 | T10326 | pobj | activator,as |
R6899 | T10329 | T10328 | amod | potent,activator |
R6900 | T10330 | T10328 | prep | for,activator |
R6901 | T10331 | T10330 | pobj | Mcm4,for |
R6902 | T10332 | T10331 | punct | /,Mcm4 |
R6903 | T10333 | T10331 | nummod | 6,Mcm4 |
R6904 | T10334 | T10331 | punct | /,Mcm4 |
R6905 | T10335 | T10331 | nummod | 7,Mcm4 |
R6906 | T10336 | T10311 | punct | .,required |
R6907 | T10338 | T10339 | nsubj | We,noticed |
R6908 | T10340 | T10339 | advmod | also,noticed |
R6909 | T10341 | T10342 | mark | that,is |
R6910 | T10342 | T10339 | ccomp | is,noticed |
R6911 | T10343 | T10344 | det | the,presence |
R6912 | T10344 | T10342 | nsubj | presence,is |
R6913 | T10345 | T10344 | prep | of,presence |
R6914 | T10346 | T10347 | det | a,structure |
R6915 | T10347 | T10345 | pobj | structure,of |
R6916 | T10348 | T10347 | amod | secondary,structure |
R6917 | T10349 | T10347 | prep | within,structure |
R6918 | T10350 | T10351 | det | the,DNA |
R6919 | T10351 | T10349 | pobj | DNA,within |
R6920 | T10352 | T10353 | amod | single,stranded |
R6921 | T10353 | T10351 | amod | stranded,DNA |
R6922 | T10354 | T10353 | punct | -,stranded |
R6923 | T10355 | T10342 | acomp | inhibitory,is |
R6924 | T10356 | T10355 | prep | for,inhibitory |
R6925 | T10357 | T10358 | compound | helicase,action |
R6926 | T10358 | T10356 | pobj | action,for |
R6927 | T10359 | T10339 | punct | .,noticed |
R6928 | T10361 | T10362 | compound | Nuclease,footprinting |
R6929 | T10362 | T10363 | compound | footprinting,assays |
R6930 | T10363 | T10364 | nsubj | assays,indicated |
R6931 | T10365 | T10366 | mark | that,interfered |
R6932 | T10366 | T10364 | ccomp | interfered,indicated |
R6933 | T10367 | T10366 | nsubjpass | binding,interfered |
R6934 | T10368 | T10366 | auxpass | was,interfered |
R6935 | T10369 | T10366 | agent | by,interfered |
R6936 | T10370 | T10371 | det | the,structure |
R6937 | T10371 | T10369 | pobj | structure,by |
R6938 | T10372 | T10371 | amod | secondary,structure |
R6939 | T10373 | T10374 | punct | (,shown |
R6940 | T10374 | T10366 | parataxis | shown,interfered |
R6941 | T10375 | T10374 | nsubj | data,shown |
R6942 | T10376 | T10374 | neg | not,shown |
R6943 | T10377 | T10374 | punct | ),shown |
R6944 | T10378 | T10364 | punct | .,indicated |
R6945 | T10380 | T10381 | advmod | Thus,concluded |
R6946 | T10382 | T10381 | punct | ", ",concluded |
R6947 | T10383 | T10381 | nsubj | we,concluded |
R6948 | T10384 | T10381 | aux | have,concluded |
R6949 | T10385 | T10386 | mark | that,activated |
R6950 | T10386 | T10381 | ccomp | activated,concluded |
R6951 | T10387 | T10388 | nmod | Mcm4,helicase |
R6952 | T10388 | T10386 | nsubjpass | helicase,activated |
R6953 | T10389 | T10387 | punct | /,Mcm4 |
R6954 | T10390 | T10387 | nummod | 6,Mcm4 |
R6955 | T10391 | T10387 | punct | /,Mcm4 |
R6956 | T10392 | T10387 | nummod | 7,Mcm4 |
R6957 | T10393 | T10386 | auxpass | is,activated |
R6958 | T10394 | T10395 | advmod | most,efficiently |
R6959 | T10395 | T10386 | advmod | efficiently,activated |
R6960 | T10396 | T10386 | agent | by,activated |
R6961 | T10397 | T10398 | amod | non-structured,DNA |
R6962 | T10398 | T10396 | pobj | DNA,by |
R6963 | T10399 | T10400 | amod | single,stranded |
R6964 | T10400 | T10398 | amod | stranded,DNA |
R6965 | T10401 | T10400 | punct | -,stranded |
R6966 | T10402 | T10398 | prep | with,DNA |
R6967 | T10403 | T10404 | compound | thymine,content |
R6968 | T10404 | T10402 | pobj | content,with |
R6969 | T10405 | T10404 | prep | of,content |
R6970 | T10406 | T10407 | nummod | 50,% |
R6971 | T10407 | T10405 | pobj | %,of |
R6972 | T10408 | T10409 | cc | or,more |
R6973 | T10409 | T10407 | nummod | more,% |
R6974 | T10410 | T10386 | punct | ", ",activated |
R6975 | T10411 | T10412 | mark | although,observed |
R6976 | T10412 | T10386 | advcl | observed,activated |
R6977 | T10413 | T10414 | amod | significant,stimulation |
R6978 | T10414 | T10412 | nsubjpass | stimulation,observed |
R6979 | T10415 | T10412 | auxpass | is,observed |
R6980 | T10416 | T10412 | advmod | also,observed |
R6981 | T10417 | T10412 | agent | by,observed |
R6982 | T10418 | T10417 | pobj | DNA,by |
R6983 | T10419 | T10418 | prep | with,DNA |
R6984 | T10420 | T10421 | amod | less,content |
R6985 | T10421 | T10419 | pobj | content,with |
R6986 | T10422 | T10421 | compound | thymine,content |
R6987 | T10423 | T10424 | punct | (,Figure |
R6988 | T10424 | T10418 | parataxis | Figure,DNA |
R6989 | T10425 | T10424 | nummod | 7,Figure |
R6990 | T10426 | T10424 | punct | ),Figure |
R6991 | T10427 | T10412 | punct | ", ",observed |
R6992 | T10428 | T10412 | advcl | suggesting,observed |
R6993 | T10429 | T10430 | mark | that,is |
R6994 | T10430 | T10428 | advcl | is,suggesting |
R6995 | T10431 | T10432 | det | the,specificity |
R6996 | T10432 | T10430 | nsubj | specificity,is |
R6997 | T10433 | T10432 | compound | sequence,specificity |
R6998 | T10434 | T10432 | prep | for,specificity |
R6999 | T10435 | T10436 | compound | Mcm,helicase |
R7000 | T10436 | T10437 | compound | helicase,activation |
R7001 | T10437 | T10434 | pobj | activation,for |
R7002 | T10438 | T10439 | advmod | rather,relaxed |
R7003 | T10439 | T10430 | acomp | relaxed,is |
R7004 | T10440 | T10430 | cc | and,is |
R7005 | T10441 | T10442 | mark | that,depend |
R7006 | T10442 | T10430 | conj | depend,is |
R7007 | T10443 | T10444 | det | the,extent |
R7008 | T10444 | T10442 | nsubj | extent,depend |
R7009 | T10445 | T10444 | prep | of,extent |
R7010 | T10446 | T10447 | det | the,activation |
R7011 | T10447 | T10445 | pobj | activation,of |
R7012 | T10448 | T10442 | aux | may,depend |
R7013 | T10449 | T10442 | prep | on,depend |
R7014 | T10450 | T10451 | det | the,context |
R7015 | T10451 | T10449 | pobj | context,on |
R7016 | T10452 | T10451 | compound | sequence,context |
R7017 | T10453 | T10381 | punct | .,concluded |
R7018 | T10455 | T10456 | nsubj | This,be |
R7019 | T10457 | T10456 | aux | would,be |
R7020 | T10458 | T10456 | acomp | reasonable,be |
R7021 | T10459 | T10456 | prep | given,be |
R7022 | T10460 | T10461 | det | the,flexibility |
R7023 | T10461 | T10459 | pobj | flexibility,given |
R7024 | T10462 | T10461 | cc | and,flexibility |
R7025 | T10463 | T10464 | amod | differential,regulation |
R7026 | T10464 | T10461 | conj | regulation,flexibility |
R7027 | T10465 | T10461 | prep | of,flexibility |
R7028 | T10466 | T10467 | compound | site,selection |
R7029 | T10467 | T10465 | pobj | selection,of |
R7030 | T10468 | T10461 | prep | for,flexibility |
R7031 | T10469 | T10468 | pobj | initiation,for |
R7032 | T10470 | T10469 | prep | of,initiation |
R7033 | T10471 | T10472 | compound | DNA,replication |
R7034 | T10472 | T10470 | pobj | replication,of |
R7035 | T10473 | T10469 | prep | during,initiation |
R7036 | T10474 | T10473 | pobj | development,during |
R7037 | T10475 | T10468 | cc | or,for |
R7038 | T10476 | T10468 | conj | in,for |
R7039 | T10477 | T10478 | amod | various,types |
R7040 | T10478 | T10476 | pobj | types,in |
R7041 | T10479 | T10478 | compound | cell,types |
R7042 | T10480 | T10461 | punct | ", ",flexibility |
R7043 | T10481 | T10482 | advmod | as,as |
R7044 | T10482 | T10461 | cc | as,flexibility |
R7045 | T10483 | T10482 | advmod | well,as |
R7046 | T10484 | T10485 | det | the,variability |
R7047 | T10485 | T10461 | conj | variability,flexibility |
R7048 | T10486 | T10485 | prep | in,variability |
R7049 | T10487 | T10488 | compound | initiation,potential |
R7050 | T10488 | T10486 | pobj | potential,in |
R7051 | T10489 | T10488 | prep | of,potential |
R7052 | T10490 | T10491 | det | each,origin |
R7053 | T10491 | T10489 | pobj | origin,of |
R7054 | T10492 | T10491 | compound | replication,origin |
R7055 | T10493 | T10491 | prep | on,origin |
R7056 | T10494 | T10495 | det | the,genome |
R7057 | T10495 | T10493 | pobj | genome,on |
R7058 | T10496 | T10497 | advmod | even,within |
R7059 | T10497 | T10485 | prep | within,variability |
R7060 | T10498 | T10499 | det | the,type |
R7061 | T10499 | T10497 | pobj | type,within |
R7062 | T10500 | T10499 | amod | single,type |
R7063 | T10501 | T10499 | compound | cell,type |
R7064 | T10502 | T10456 | punct | .,be |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9820 | 41-49 | SO_EXT:biological_sequence | denotes | sequence |
T9821 | 65-84 | CHEBI_SO_EXT:single_stranded_DNA | denotes | single-stranded DNA |
T9822 | 92-100 | GO_EXT:0004386 | denotes | helicase |
T9823 | 113-116 | GO:0042555 | denotes | Mcm |
T9824 | 144-151 | CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | thymine |
T9825 | 197-205 | GO_EXT:0004386 | denotes | helicase |
T9826 | 264-271 | CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | thymine |
T9827 | 339-346 | CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | thymine |
T9828 | 347-355 | CHEBI_EXT:residue | denotes | residues |
T9829 | 395-402 | SO_EXT:sequence_repeat_unit_or_region | denotes | repeats |
T9830 | 409-422 | CHEBI_SO_EXT:dinucleotide | denotes | dinucleotides |
T9831 | 456-460 | PR_EXT:000010246 | denotes | Mcm4 |
T9832 | 456-464 | GO:0097373 | denotes | Mcm4/6/7 |
T9833 | 536-555 | CHEBI_SO_EXT:single_stranded_DNA | denotes | single-stranded DNA |
T9834 | 574-582 | GO_EXT:0004386 | denotes | helicase |
T9835 | 591-599 | GO_EXT:0004518 | denotes | Nuclease |
T9836 | 635-642 | CHEMINF_GO_EXT:chemical_binding_or_bond_formation | denotes | binding |
T9837 | 732-736 | PR_EXT:000010246 | denotes | Mcm4 |
T9838 | 732-740 | GO:0097373 | denotes | Mcm4/6/7 |
T9839 | 741-749 | GO_EXT:0004386 | denotes | helicase |
T9840 | 798-817 | CHEBI_SO_EXT:single_stranded_DNA | denotes | single-stranded DNA |
T9841 | 823-830 | CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | thymine |
T9842 | 908-911 | CHEBI_SO_EXT:DNA | denotes | DNA |
T9843 | 922-929 | CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group | denotes | thymine |
T9844 | 970-978 | SO_EXT:biological_sequence | denotes | sequence |
T9845 | 995-998 | GO:0042555 | denotes | Mcm |
T9846 | 999-1007 | GO_EXT:0004386 | denotes | helicase |
T9847 | 1093-1101 | SO_EXT:biological_sequence | denotes | sequence |
T9848 | 1175-1185 | GO:0065007 | denotes | regulation |
T9849 | 1208-1237 | GO:0006270 | denotes | initiation of DNA replication |
T9850 | 1222-1225 | CHEBI_SO_EXT:DNA | denotes | DNA |
T9851 | 1271-1275 | CL_GO_EXT:cell | denotes | cell |
T9852 | 1342-1353 | GO:0006260 | denotes | replication |
T9853 | 1342-1360 | SO_EXT:0000296 | denotes | replication origin |
T9854 | 1368-1374 | SO_EXT:0001026 | denotes | genome |
T9855 | 1398-1402 | CL_GO_EXT:cell | denotes | cell |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9725 | 65-80 | SO:0000984 | denotes | single-stranded |
T9726 | 113-116 | GO:0042555 | denotes | Mcm |
T9727 | 456-460 | PR:000010246 | denotes | Mcm4 |
T9728 | 456-464 | GO:0097373 | denotes | Mcm4/6/7 |
T9729 | 536-551 | SO:0000984 | denotes | single-stranded |
T9730 | 732-736 | PR:000010246 | denotes | Mcm4 |
T9731 | 732-740 | GO:0097373 | denotes | Mcm4/6/7 |
T9732 | 798-813 | SO:0000984 | denotes | single-stranded |
T9733 | 995-998 | GO:0042555 | denotes | Mcm |
T9734 | 1175-1185 | GO:0065007 | denotes | regulation |
T9735 | 1208-1237 | GO:0006270 | denotes | initiation of DNA replication |
T9736 | 1342-1353 | GO:0006260 | denotes | replication |
T9737 | 1342-1360 | SO:0000296 | denotes | replication origin |
T9738 | 1368-1374 | SO:0001026 | denotes | genome |