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PMC:1140370 / 28673-31007 JSONTXT

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Id Subject Object Predicate Lexical cue
T9088 0-5 NNS denotes Modes
T9089 6-8 IN denotes of
T9090 9-16 NN denotes binding
T9091 17-20 CC denotes and
T9092 21-31 NN denotes activation
T9093 32-34 IN denotes of
T9094 35-39 NN denotes Mcm4
T9095 44-52 NN denotes helicase
T9096 39-40 HYPH denotes /
T9097 40-41 CD denotes 6
T9098 41-42 HYPH denotes /
T9099 42-43 CD denotes 7
T9100 53-55 IN denotes on
T9101 56-57 DT denotes a
T9102 65-74 NN denotes structure
T9103 58-64 NN denotes bubble
T9104 74-181 sentence denotes Initiation of DNA replication is associated with localized melting of duplex DNA near replication origins.
T9105 75-85 NN denotes Initiation
T9106 108-118 VBN denotes associated
T9107 86-88 IN denotes of
T9108 89-92 NN denotes DNA
T9109 93-104 NN denotes replication
T9110 105-107 VBZ denotes is
T9111 119-123 IN denotes with
T9112 124-133 VBN denotes localized
T9113 134-141 NN denotes melting
T9114 142-144 IN denotes of
T9115 145-151 NN denotes duplex
T9116 152-155 NN denotes DNA
T9117 156-160 JJ denotes near
T9118 161-172 NN denotes replication
T9119 173-180 NNS denotes origins
T9120 180-181 . denotes .
T9121 181-300 sentence denotes Helicases are loaded onto replication forks through the melted region, induced by initiator binding, in bacteria (32).
T9122 182-191 NNS denotes Helicases
T9123 196-202 VBN denotes loaded
T9124 192-195 VBP denotes are
T9125 203-207 IN denotes onto
T9126 208-219 NN denotes replication
T9127 220-225 NNS denotes forks
T9128 226-233 IN denotes through
T9129 234-237 DT denotes the
T9130 245-251 NN denotes region
T9131 238-244 VBN denotes melted
T9132 251-253 , denotes ,
T9133 253-260 VBN denotes induced
T9134 261-263 IN denotes by
T9135 264-273 NN denotes initiator
T9136 274-281 NN denotes binding
T9137 281-283 , denotes ,
T9138 283-285 IN denotes in
T9139 286-294 NNS denotes bacteria
T9140 295-296 -LRB- denotes (
T9141 296-298 CD denotes 32
T9142 298-299 -RRB- denotes )
T9143 299-300 . denotes .
T9144 300-431 sentence denotes We previously reported that Mcm4/6/7 can be loaded onto a bubble-like structure and can serve as a DNA helicase at the forks (13).
T9145 301-303 PRP denotes We
T9146 315-323 VBD denotes reported
T9147 304-314 RB denotes previously
T9148 324-328 IN denotes that
T9149 345-351 VBN denotes loaded
T9150 329-333 NN denotes Mcm4
T9151 333-334 HYPH denotes /
T9152 334-335 CD denotes 6
T9153 335-336 HYPH denotes /
T9154 336-337 CD denotes 7
T9155 338-341 MD denotes can
T9156 342-344 VB denotes be
T9157 352-356 IN denotes onto
T9158 357-358 DT denotes a
T9159 371-380 NN denotes structure
T9160 359-365 NN denotes bubble
T9161 366-370 JJ denotes like
T9162 365-366 HYPH denotes -
T9163 381-384 CC denotes and
T9164 385-388 MD denotes can
T9165 389-394 VB denotes serve
T9166 395-397 IN denotes as
T9167 398-399 DT denotes a
T9168 404-412 NN denotes helicase
T9169 400-403 NN denotes DNA
T9170 413-415 IN denotes at
T9171 416-419 DT denotes the
T9172 420-425 NNS denotes forks
T9173 426-427 -LRB- denotes (
T9174 427-429 CD denotes 13
T9175 429-430 -RRB- denotes )
T9176 430-431 . denotes .
T9177 431-625 sentence denotes The ability of Mcm4/6/7 to unwind the bubble substrate but not the conventional duplex DNA (Figures 2 and 13) indicates that Mcm can be loaded through the single-stranded segment of the bubble.
T9178 432-435 DT denotes The
T9179 436-443 NN denotes ability
T9180 542-551 VBZ denotes indicates
T9181 444-446 IN denotes of
T9182 447-451 NN denotes Mcm4
T9183 451-452 HYPH denotes /
T9184 452-453 CD denotes 6
T9185 453-454 HYPH denotes /
T9186 454-455 CD denotes 7
T9187 456-458 TO denotes to
T9188 459-465 VB denotes unwind
T9189 466-469 DT denotes the
T9190 477-486 NN denotes substrate
T9191 470-476 NN denotes bubble
T9192 487-490 CC denotes but
T9193 491-494 RB denotes not
T9194 495-498 DT denotes the
T9195 519-522 NN denotes DNA
T9196 499-511 JJ denotes conventional
T9197 512-518 NN denotes duplex
T9198 523-524 -LRB- denotes (
T9199 532-533 CD denotes 2
T9200 524-531 NNS denotes Figures
T9201 534-537 CC denotes and
T9202 538-540 CD denotes 13
T9203 540-541 -RRB- denotes )
T9204 552-556 IN denotes that
T9205 568-574 VBN denotes loaded
T9206 557-560 NN denotes Mcm
T9207 561-564 MD denotes can
T9208 565-567 VB denotes be
T9209 575-582 IN denotes through
T9210 583-586 DT denotes the
T9211 603-610 NN denotes segment
T9212 587-593 JJ denotes single
T9213 594-602 VBN denotes stranded
T9214 593-594 HYPH denotes -
T9215 611-613 IN denotes of
T9216 614-617 DT denotes the
T9217 618-624 NN denotes bubble
T9218 624-625 . denotes .
T9219 625-778 sentence denotes Furthermore, the Mcm4/6/7 complex displays marked preference for thymine-rich sequences within the single-stranded segment for helicase activation (13).
T9220 626-637 RB denotes Furthermore
T9221 660-668 VBZ denotes displays
T9222 637-639 , denotes ,
T9223 639-642 DT denotes the
T9224 652-659 NN denotes complex
T9225 643-647 NN denotes Mcm4
T9226 647-648 HYPH denotes /
T9227 648-649 CD denotes 6
T9228 649-650 HYPH denotes /
T9229 650-651 CD denotes 7
T9230 669-675 JJ denotes marked
T9231 676-686 NN denotes preference
T9232 687-690 IN denotes for
T9233 691-698 NN denotes thymine
T9234 699-703 JJ denotes rich
T9235 698-699 HYPH denotes -
T9236 704-713 NNS denotes sequences
T9237 714-720 IN denotes within
T9238 721-724 DT denotes the
T9239 741-748 NN denotes segment
T9240 725-731 JJ denotes single
T9241 732-740 VBN denotes stranded
T9242 731-732 HYPH denotes -
T9243 749-752 IN denotes for
T9244 753-761 NN denotes helicase
T9245 762-772 NN denotes activation
T9246 773-774 -LRB- denotes (
T9247 774-776 CD denotes 13
T9248 776-777 -RRB- denotes )
T9249 777-778 . denotes .
T9250 778-1086 sentence denotes The results in this report indicate that helicase action of Mcm4/6/7 on synthetic bubbles may depend on the presence of an unpaired region of sufficient length (at least 40 nt), which may permit assembly of a double-hexameric complex on the substrate DNA, similar to SV40 T-antigen protein (Figure 2A) (21).
T9251 779-782 DT denotes The
T9252 783-790 NNS denotes results
T9253 806-814 VBP denotes indicate
T9254 791-793 IN denotes in
T9255 794-798 DT denotes this
T9256 799-805 NN denotes report
T9257 815-819 IN denotes that
T9258 873-879 VB denotes depend
T9259 820-828 NN denotes helicase
T9260 829-835 NN denotes action
T9261 836-838 IN denotes of
T9262 839-843 NN denotes Mcm4
T9263 843-844 HYPH denotes /
T9264 844-845 CD denotes 6
T9265 845-846 HYPH denotes /
T9266 846-847 CD denotes 7
T9267 848-850 IN denotes on
T9268 851-860 JJ denotes synthetic
T9269 861-868 NNS denotes bubbles
T9270 869-872 MD denotes may
T9271 880-882 IN denotes on
T9272 883-886 DT denotes the
T9273 887-895 NN denotes presence
T9274 896-898 IN denotes of
T9275 899-901 DT denotes an
T9276 911-917 NN denotes region
T9277 902-910 JJ denotes unpaired
T9278 918-920 IN denotes of
T9279 921-931 JJ denotes sufficient
T9280 932-938 NN denotes length
T9281 939-940 -LRB- denotes (
T9282 952-954 NN denotes nt
T9283 940-942 RB denotes at
T9284 943-948 RBS denotes least
T9285 949-951 CD denotes 40
T9286 954-955 -RRB- denotes )
T9287 955-957 , denotes ,
T9288 957-962 WDT denotes which
T9289 967-973 VB denotes permit
T9290 963-966 MD denotes may
T9291 974-982 NN denotes assembly
T9292 983-985 IN denotes of
T9293 986-987 DT denotes a
T9294 1005-1012 NN denotes complex
T9295 988-994 JJ denotes double
T9296 995-1004 JJ denotes hexameric
T9297 994-995 HYPH denotes -
T9298 1013-1015 IN denotes on
T9299 1016-1019 DT denotes the
T9300 1030-1033 NN denotes DNA
T9301 1020-1029 NN denotes substrate
T9302 1033-1035 , denotes ,
T9303 1035-1042 JJ denotes similar
T9304 1043-1045 IN denotes to
T9305 1046-1050 NN denotes SV40
T9306 1061-1068 NN denotes protein
T9307 1051-1052 NN denotes T
T9308 1053-1060 NN denotes antigen
T9309 1052-1053 HYPH denotes -
T9310 1069-1070 -LRB- denotes (
T9311 1077-1079 NN denotes 2A
T9312 1070-1076 NN denotes Figure
T9313 1079-1080 -RRB- denotes )
T9314 1081-1082 -LRB- denotes (
T9315 1082-1084 CD denotes 21
T9316 1084-1085 -RRB- denotes )
T9317 1085-1086 . denotes .
T9318 1086-1245 sentence denotes When one strand of the single-stranded segment in T-rich bubble was replaced by guanine-rich sequences, the efficiency of unwinding was significantly reduced.
T9319 1087-1091 WRB denotes When
T9320 1155-1163 VBN denotes replaced
T9321 1092-1095 CD denotes one
T9322 1096-1102 NN denotes strand
T9323 1103-1105 IN denotes of
T9324 1106-1109 DT denotes the
T9325 1126-1133 NN denotes segment
T9326 1110-1116 JJ denotes single
T9327 1117-1125 VBN denotes stranded
T9328 1116-1117 HYPH denotes -
T9329 1134-1136 IN denotes in
T9330 1137-1138 NN denotes T
T9331 1139-1143 JJ denotes rich
T9332 1138-1139 HYPH denotes -
T9333 1144-1150 NN denotes bubble
T9334 1151-1154 VBD denotes was
T9335 1237-1244 VBN denotes reduced
T9336 1164-1166 IN denotes by
T9337 1167-1174 NN denotes guanine
T9338 1175-1179 JJ denotes rich
T9339 1174-1175 HYPH denotes -
T9340 1180-1189 NNS denotes sequences
T9341 1189-1191 , denotes ,
T9342 1191-1194 DT denotes the
T9343 1195-1205 NN denotes efficiency
T9344 1206-1208 IN denotes of
T9345 1209-1218 NN denotes unwinding
T9346 1219-1222 VBD denotes was
T9347 1223-1236 RB denotes significantly
T9348 1244-1245 . denotes .
T9349 1245-1429 sentence denotes Our footprinting analyses showed that Mcm4/6/7 strongly protects 25 nt single-stranded DNA segment adjacent to each branch point and proximal to 5′ ends of both strands of the bubble.
T9350 1246-1249 PRP$ denotes Our
T9351 1263-1271 NNS denotes analyses
T9352 1250-1262 NN denotes footprinting
T9353 1272-1278 VBD denotes showed
T9354 1279-1283 IN denotes that
T9355 1302-1310 VBZ denotes protects
T9356 1284-1288 NN denotes Mcm4
T9357 1288-1289 HYPH denotes /
T9358 1289-1290 CD denotes 6
T9359 1290-1291 HYPH denotes /
T9360 1291-1292 CD denotes 7
T9361 1293-1301 RB denotes strongly
T9362 1311-1313 CD denotes 25
T9363 1314-1316 NN denotes nt
T9364 1337-1344 NN denotes segment
T9365 1317-1323 JJ denotes single
T9366 1324-1332 VBN denotes stranded
T9367 1323-1324 HYPH denotes -
T9368 1333-1336 NN denotes DNA
T9369 1345-1353 JJ denotes adjacent
T9370 1354-1356 IN denotes to
T9371 1357-1361 DT denotes each
T9372 1369-1374 NN denotes point
T9373 1362-1368 NN denotes branch
T9374 1375-1378 CC denotes and
T9375 1379-1387 JJ denotes proximal
T9376 1388-1390 IN denotes to
T9377 1391-1392 CD denotes 5
T9378 1394-1398 NNS denotes ends
T9379 1392-1393 SYM denotes ′
T9380 1399-1401 IN denotes of
T9381 1402-1406 DT denotes both
T9382 1407-1414 NNS denotes strands
T9383 1415-1417 IN denotes of
T9384 1418-1421 DT denotes the
T9385 1422-1428 NN denotes bubble
T9386 1428-1429 . denotes .
T9387 1429-1671 sentence denotes At each fork, one Mcm4/6/7 complex is likely to encircle the single-stranded DNA strand and two hexamers may bind symmetrically to the bubble substrate, forming a double hexameric structure on the bubble (see schematic drawing of Figure 1A).
T9388 1430-1432 IN denotes At
T9389 1465-1467 VBZ denotes is
T9390 1433-1437 DT denotes each
T9391 1438-1442 NN denotes fork
T9392 1442-1444 , denotes ,
T9393 1444-1447 CD denotes one
T9394 1457-1464 NN denotes complex
T9395 1448-1452 NN denotes Mcm4
T9396 1452-1453 HYPH denotes /
T9397 1453-1454 CD denotes 6
T9398 1454-1455 HYPH denotes /
T9399 1455-1456 CD denotes 7
T9400 1468-1474 JJ denotes likely
T9401 1475-1477 TO denotes to
T9402 1478-1486 VB denotes encircle
T9403 1487-1490 DT denotes the
T9404 1511-1517 NN denotes strand
T9405 1491-1497 JJ denotes single
T9406 1498-1506 VBN denotes stranded
T9407 1497-1498 HYPH denotes -
T9408 1507-1510 NN denotes DNA
T9409 1518-1521 CC denotes and
T9410 1522-1525 CD denotes two
T9411 1526-1534 NNS denotes hexamers
T9412 1539-1543 VB denotes bind
T9413 1535-1538 MD denotes may
T9414 1544-1557 RB denotes symmetrically
T9415 1558-1560 IN denotes to
T9416 1561-1564 DT denotes the
T9417 1572-1581 NN denotes substrate
T9418 1565-1571 NN denotes bubble
T9419 1581-1583 , denotes ,
T9420 1583-1590 VBG denotes forming
T9421 1591-1592 DT denotes a
T9422 1610-1619 NN denotes structure
T9423 1593-1599 JJ denotes double
T9424 1600-1609 JJ denotes hexameric
T9425 1620-1622 IN denotes on
T9426 1623-1626 DT denotes the
T9427 1627-1633 NN denotes bubble
T9428 1634-1635 -LRB- denotes (
T9429 1635-1638 VB denotes see
T9430 1639-1648 JJ denotes schematic
T9431 1649-1656 NN denotes drawing
T9432 1657-1659 IN denotes of
T9433 1660-1666 NN denotes Figure
T9434 1667-1669 NN denotes 1A
T9435 1669-1670 -RRB- denotes )
T9436 1670-1671 . denotes .
T9437 1671-1860 sentence denotes Efficient unwinding into both directions may require simultaneous activation of both hexamers which may sit at the center while extruding the unwound single-stranded DNA through the rings.
T9438 1672-1681 JJ denotes Efficient
T9439 1682-1691 NN denotes unwinding
T9440 1717-1724 VB denotes require
T9441 1692-1696 IN denotes into
T9442 1697-1701 DT denotes both
T9443 1702-1712 NNS denotes directions
T9444 1713-1716 MD denotes may
T9445 1725-1737 JJ denotes simultaneous
T9446 1738-1748 NN denotes activation
T9447 1749-1751 IN denotes of
T9448 1752-1756 DT denotes both
T9449 1757-1765 NNS denotes hexamers
T9450 1766-1771 WDT denotes which
T9451 1776-1779 VB denotes sit
T9452 1772-1775 MD denotes may
T9453 1780-1782 IN denotes at
T9454 1783-1786 DT denotes the
T9455 1787-1793 NN denotes center
T9456 1794-1799 IN denotes while
T9457 1800-1809 VBG denotes extruding
T9458 1810-1813 DT denotes the
T9459 1838-1841 NN denotes DNA
T9460 1814-1821 JJ denotes unwound
T9461 1822-1828 JJ denotes single
T9462 1829-1837 VBN denotes stranded
T9463 1828-1829 HYPH denotes -
T9464 1842-1849 IN denotes through
T9465 1850-1853 DT denotes the
T9466 1854-1859 NNS denotes rings
T9467 1859-1860 . denotes .
T9468 1860-1956 sentence denotes This may closely resemble the proposed modes of binding and helicase actions of T-antigen (21).
T9469 1861-1865 DT denotes This
T9470 1878-1886 VB denotes resemble
T9471 1866-1869 MD denotes may
T9472 1870-1877 RB denotes closely
T9473 1887-1890 DT denotes the
T9474 1900-1905 NNS denotes modes
T9475 1891-1899 VBN denotes proposed
T9476 1906-1908 IN denotes of
T9477 1909-1916 NN denotes binding
T9478 1930-1937 NNS denotes actions
T9479 1917-1920 CC denotes and
T9480 1921-1929 NN denotes helicase
T9481 1938-1940 IN denotes of
T9482 1941-1942 NN denotes T
T9483 1943-1950 NN denotes antigen
T9484 1942-1943 HYPH denotes -
T9485 1951-1952 -LRB- denotes (
T9486 1952-1954 CD denotes 21
T9487 1954-1955 -RRB- denotes )
T9488 1955-1956 . denotes .
T9489 1956-2334 sentence denotes Although we cannot totally exclude the possibility that one Mcm4/6/7 hexamer at each fork unwinds the duplex independently, ring-shaped structures of mouse and archea MCM, as revealed by electron microscopy, bear much similarity to the recently solved structure of the SV40 large T-antigen (4,6), and are in favor of the double-hexameric structure of mouse Mcm on a bubble DNA.
T9490 1957-1965 IN denotes Although
T9491 1984-1991 VB denotes exclude
T9492 1966-1968 PRP denotes we
T9493 1969-1972 MD denotes can
T9494 1972-1975 RB denotes not
T9495 1976-1983 RB denotes totally
T9496 2165-2169 VBP denotes bear
T9497 1992-1995 DT denotes the
T9498 1996-2007 NN denotes possibility
T9499 2008-2012 IN denotes that
T9500 2047-2054 VBZ denotes unwinds
T9501 2013-2016 CD denotes one
T9502 2026-2033 NN denotes hexamer
T9503 2017-2021 NN denotes Mcm4
T9504 2021-2022 HYPH denotes /
T9505 2022-2023 CD denotes 6
T9506 2023-2024 HYPH denotes /
T9507 2024-2025 CD denotes 7
T9508 2034-2036 IN denotes at
T9509 2037-2041 DT denotes each
T9510 2042-2046 NN denotes fork
T9511 2055-2058 DT denotes the
T9512 2059-2065 NN denotes duplex
T9513 2066-2079 RB denotes independently
T9514 2079-2081 , denotes ,
T9515 2081-2085 NN denotes ring
T9516 2086-2092 VBN denotes shaped
T9517 2085-2086 HYPH denotes -
T9518 2093-2103 NNS denotes structures
T9519 2104-2106 IN denotes of
T9520 2107-2112 NN denotes mouse
T9521 2124-2127 NN denotes MCM
T9522 2113-2116 CC denotes and
T9523 2117-2123 NN denotes archea
T9524 2127-2129 , denotes ,
T9525 2129-2131 IN denotes as
T9526 2132-2140 VBN denotes revealed
T9527 2141-2143 IN denotes by
T9528 2144-2152 NN denotes electron
T9529 2153-2163 NN denotes microscopy
T9530 2163-2165 , denotes ,
T9531 2170-2174 JJ denotes much
T9532 2175-2185 NN denotes similarity
T9533 2186-2188 IN denotes to
T9534 2189-2192 DT denotes the
T9535 2209-2218 NN denotes structure
T9536 2193-2201 RB denotes recently
T9537 2202-2208 VBN denotes solved
T9538 2219-2221 IN denotes of
T9539 2222-2225 DT denotes the
T9540 2239-2246 NN denotes antigen
T9541 2226-2230 NN denotes SV40
T9542 2231-2236 JJ denotes large
T9543 2237-2238 NN denotes T
T9544 2238-2239 HYPH denotes -
T9545 2247-2248 -LRB- denotes (
T9546 2250-2251 CD denotes 6
T9547 2248-2249 CD denotes 4
T9548 2249-2250 , denotes ,
T9549 2251-2252 -RRB- denotes )
T9550 2252-2254 , denotes ,
T9551 2254-2257 CC denotes and
T9552 2258-2261 VBP denotes are
T9553 2262-2264 IN denotes in
T9554 2265-2270 NN denotes favor
T9555 2271-2273 IN denotes of
T9556 2274-2277 DT denotes the
T9557 2295-2304 NN denotes structure
T9558 2278-2284 JJ denotes double
T9559 2285-2294 JJ denotes hexameric
T9560 2284-2285 HYPH denotes -
T9561 2305-2307 IN denotes of
T9562 2308-2313 NN denotes mouse
T9563 2314-2317 NN denotes Mcm
T9564 2318-2320 IN denotes on
T9565 2321-2322 DT denotes a
T9566 2330-2333 NN denotes DNA
T9567 2323-2329 NN denotes bubble
T9568 2333-2334 . denotes .
R5997 T9089 T9088 prep of,Modes
R5998 T9090 T9089 pobj binding,of
R5999 T9091 T9090 cc and,binding
R6000 T9092 T9090 conj activation,binding
R6001 T9093 T9090 prep of,binding
R6002 T9094 T9095 nmod Mcm4,helicase
R6003 T9095 T9093 pobj helicase,of
R6004 T9096 T9094 punct /,Mcm4
R6005 T9097 T9094 nummod 6,Mcm4
R6006 T9098 T9094 punct /,Mcm4
R6007 T9099 T9094 nummod 7,Mcm4
R6008 T9100 T9090 prep on,binding
R6009 T9101 T9102 det a,structure
R6010 T9102 T9100 pobj structure,on
R6011 T9103 T9102 compound bubble,structure
R6012 T9105 T9106 nsubjpass Initiation,associated
R6013 T9107 T9105 prep of,Initiation
R6014 T9108 T9109 compound DNA,replication
R6015 T9109 T9107 pobj replication,of
R6016 T9110 T9106 auxpass is,associated
R6017 T9111 T9106 prep with,associated
R6018 T9112 T9113 amod localized,melting
R6019 T9113 T9111 pobj melting,with
R6020 T9114 T9113 prep of,melting
R6021 T9115 T9116 compound duplex,DNA
R6022 T9116 T9114 pobj DNA,of
R6023 T9117 T9113 amod near,melting
R6024 T9118 T9119 compound replication,origins
R6025 T9119 T9117 npadvmod origins,near
R6026 T9120 T9106 punct .,associated
R6027 T9122 T9123 nsubjpass Helicases,loaded
R6028 T9124 T9123 auxpass are,loaded
R6029 T9125 T9123 prep onto,loaded
R6030 T9126 T9127 compound replication,forks
R6031 T9127 T9125 pobj forks,onto
R6032 T9128 T9123 prep through,loaded
R6033 T9129 T9130 det the,region
R6034 T9130 T9128 pobj region,through
R6035 T9131 T9130 amod melted,region
R6036 T9132 T9130 punct ", ",region
R6037 T9133 T9130 acl induced,region
R6038 T9134 T9133 prep by,induced
R6039 T9135 T9136 compound initiator,binding
R6040 T9136 T9134 pobj binding,by
R6041 T9137 T9123 punct ", ",loaded
R6042 T9138 T9123 prep in,loaded
R6043 T9139 T9138 pobj bacteria,in
R6044 T9140 T9141 punct (,32
R6045 T9141 T9123 parataxis 32,loaded
R6046 T9142 T9141 punct ),32
R6047 T9143 T9123 punct .,loaded
R6048 T9145 T9146 nsubj We,reported
R6049 T9147 T9146 advmod previously,reported
R6050 T9148 T9149 mark that,loaded
R6051 T9149 T9146 ccomp loaded,reported
R6052 T9150 T9149 nsubjpass Mcm4,loaded
R6053 T9151 T9150 punct /,Mcm4
R6054 T9152 T9150 nummod 6,Mcm4
R6055 T9153 T9150 punct /,Mcm4
R6056 T9154 T9150 nummod 7,Mcm4
R6057 T9155 T9149 aux can,loaded
R6058 T9156 T9149 auxpass be,loaded
R6059 T9157 T9149 prep onto,loaded
R6060 T9158 T9159 det a,structure
R6061 T9159 T9157 pobj structure,onto
R6062 T9160 T9161 npadvmod bubble,like
R6063 T9161 T9159 amod like,structure
R6064 T9162 T9161 punct -,like
R6065 T9163 T9146 cc and,reported
R6066 T9164 T9165 aux can,serve
R6067 T9165 T9146 conj serve,reported
R6068 T9166 T9165 prep as,serve
R6069 T9167 T9168 det a,helicase
R6070 T9168 T9166 pobj helicase,as
R6071 T9169 T9168 compound DNA,helicase
R6072 T9170 T9165 prep at,serve
R6073 T9171 T9172 det the,forks
R6074 T9172 T9170 pobj forks,at
R6075 T9173 T9174 punct (,13
R6076 T9174 T9165 parataxis 13,serve
R6077 T9175 T9174 punct ),13
R6078 T9176 T9146 punct .,reported
R6079 T9178 T9179 det The,ability
R6080 T9179 T9180 nsubj ability,indicates
R6081 T9181 T9179 prep of,ability
R6082 T9182 T9181 pobj Mcm4,of
R6083 T9183 T9182 punct /,Mcm4
R6084 T9184 T9182 nummod 6,Mcm4
R6085 T9185 T9182 punct /,Mcm4
R6086 T9186 T9182 nummod 7,Mcm4
R6087 T9187 T9188 aux to,unwind
R6088 T9188 T9179 acl unwind,ability
R6089 T9189 T9190 det the,substrate
R6090 T9190 T9188 dobj substrate,unwind
R6091 T9191 T9190 compound bubble,substrate
R6092 T9192 T9190 cc but,substrate
R6093 T9193 T9192 neg not,but
R6094 T9194 T9195 det the,DNA
R6095 T9195 T9190 conj DNA,substrate
R6096 T9196 T9195 amod conventional,DNA
R6097 T9197 T9195 compound duplex,DNA
R6098 T9198 T9199 punct (,2
R6099 T9199 T9188 parataxis 2,unwind
R6100 T9200 T9199 nmod Figures,2
R6101 T9201 T9199 cc and,2
R6102 T9202 T9199 conj 13,2
R6103 T9203 T9199 punct ),2
R6104 T9204 T9205 mark that,loaded
R6105 T9205 T9180 ccomp loaded,indicates
R6106 T9206 T9205 nsubjpass Mcm,loaded
R6107 T9207 T9205 aux can,loaded
R6108 T9208 T9205 auxpass be,loaded
R6109 T9209 T9205 prep through,loaded
R6110 T9210 T9211 det the,segment
R6111 T9211 T9209 pobj segment,through
R6112 T9212 T9213 amod single,stranded
R6113 T9213 T9211 amod stranded,segment
R6114 T9214 T9213 punct -,stranded
R6115 T9215 T9211 prep of,segment
R6116 T9216 T9217 det the,bubble
R6117 T9217 T9215 pobj bubble,of
R6118 T9218 T9180 punct .,indicates
R6119 T9220 T9221 advmod Furthermore,displays
R6120 T9222 T9221 punct ", ",displays
R6121 T9223 T9224 det the,complex
R6122 T9224 T9221 nsubj complex,displays
R6123 T9225 T9224 nmod Mcm4,complex
R6124 T9226 T9225 punct /,Mcm4
R6125 T9227 T9225 nummod 6,Mcm4
R6126 T9228 T9225 punct /,Mcm4
R6127 T9229 T9225 nummod 7,Mcm4
R6128 T9230 T9231 amod marked,preference
R6129 T9231 T9221 dobj preference,displays
R6130 T9232 T9231 prep for,preference
R6131 T9233 T9234 npadvmod thymine,rich
R6132 T9234 T9236 amod rich,sequences
R6133 T9235 T9234 punct -,rich
R6134 T9236 T9232 pobj sequences,for
R6135 T9237 T9221 prep within,displays
R6136 T9238 T9239 det the,segment
R6137 T9239 T9237 pobj segment,within
R6138 T9240 T9241 amod single,stranded
R6139 T9241 T9239 amod stranded,segment
R6140 T9242 T9241 punct -,stranded
R6141 T9243 T9239 prep for,segment
R6142 T9244 T9245 compound helicase,activation
R6143 T9245 T9243 pobj activation,for
R6144 T9246 T9247 punct (,13
R6145 T9247 T9221 parataxis 13,displays
R6146 T9248 T9247 punct ),13
R6147 T9249 T9221 punct .,displays
R6148 T9251 T9252 det The,results
R6149 T9252 T9253 nsubj results,indicate
R6150 T9254 T9252 prep in,results
R6151 T9255 T9256 det this,report
R6152 T9256 T9254 pobj report,in
R6153 T9257 T9258 mark that,depend
R6154 T9258 T9253 ccomp depend,indicate
R6155 T9259 T9260 compound helicase,action
R6156 T9260 T9258 nsubj action,depend
R6157 T9261 T9260 prep of,action
R6158 T9262 T9261 pobj Mcm4,of
R6159 T9263 T9262 punct /,Mcm4
R6160 T9264 T9262 nummod 6,Mcm4
R6161 T9265 T9262 punct /,Mcm4
R6162 T9266 T9262 nummod 7,Mcm4
R6163 T9267 T9260 prep on,action
R6164 T9268 T9269 amod synthetic,bubbles
R6165 T9269 T9267 pobj bubbles,on
R6166 T9270 T9258 aux may,depend
R6167 T9271 T9258 prep on,depend
R6168 T9272 T9273 det the,presence
R6169 T9273 T9271 pobj presence,on
R6170 T9274 T9273 prep of,presence
R6171 T9275 T9276 det an,region
R6172 T9276 T9274 pobj region,of
R6173 T9277 T9276 amod unpaired,region
R6174 T9278 T9276 prep of,region
R6175 T9279 T9280 amod sufficient,length
R6176 T9280 T9278 pobj length,of
R6177 T9281 T9282 punct (,nt
R6178 T9282 T9280 parataxis nt,length
R6179 T9283 T9284 advmod at,least
R6180 T9284 T9285 advmod least,40
R6181 T9285 T9282 nummod 40,nt
R6182 T9286 T9282 punct ),nt
R6183 T9287 T9276 punct ", ",region
R6184 T9288 T9289 dep which,permit
R6185 T9289 T9276 relcl permit,region
R6186 T9290 T9289 aux may,permit
R6187 T9291 T9289 dobj assembly,permit
R6188 T9292 T9291 prep of,assembly
R6189 T9293 T9294 det a,complex
R6190 T9294 T9292 pobj complex,of
R6191 T9295 T9296 amod double,hexameric
R6192 T9296 T9294 amod hexameric,complex
R6193 T9297 T9296 punct -,hexameric
R6194 T9298 T9294 prep on,complex
R6195 T9299 T9300 det the,DNA
R6196 T9300 T9298 pobj DNA,on
R6197 T9301 T9300 compound substrate,DNA
R6198 T9302 T9294 punct ", ",complex
R6199 T9303 T9294 amod similar,complex
R6200 T9304 T9303 prep to,similar
R6201 T9305 T9306 compound SV40,protein
R6202 T9306 T9304 pobj protein,to
R6203 T9307 T9308 compound T,antigen
R6204 T9308 T9306 compound antigen,protein
R6205 T9309 T9308 punct -,antigen
R6206 T9310 T9311 punct (,2A
R6207 T9311 T9304 parataxis 2A,to
R6208 T9312 T9311 compound Figure,2A
R6209 T9313 T9311 punct ),2A
R6210 T9314 T9315 punct (,21
R6211 T9315 T9289 parataxis 21,permit
R6212 T9316 T9315 punct ),21
R6213 T9317 T9253 punct .,indicate
R6214 T9319 T9320 advmod When,replaced
R6215 T9320 T9335 advcl replaced,reduced
R6216 T9321 T9322 nummod one,strand
R6217 T9322 T9320 nsubjpass strand,replaced
R6218 T9323 T9322 prep of,strand
R6219 T9324 T9325 det the,segment
R6220 T9325 T9323 pobj segment,of
R6221 T9326 T9327 amod single,stranded
R6222 T9327 T9325 amod stranded,segment
R6223 T9328 T9327 punct -,stranded
R6224 T9329 T9322 prep in,strand
R6225 T9330 T9331 npadvmod T,rich
R6226 T9331 T9333 amod rich,bubble
R6227 T9332 T9331 punct -,rich
R6228 T9333 T9329 pobj bubble,in
R6229 T9334 T9320 auxpass was,replaced
R6230 T9336 T9320 agent by,replaced
R6231 T9337 T9338 npadvmod guanine,rich
R6232 T9338 T9340 amod rich,sequences
R6233 T9339 T9338 punct -,rich
R6234 T9340 T9336 pobj sequences,by
R6235 T9341 T9335 punct ", ",reduced
R6236 T9342 T9343 det the,efficiency
R6237 T9343 T9335 nsubjpass efficiency,reduced
R6238 T9344 T9343 prep of,efficiency
R6239 T9345 T9344 pobj unwinding,of
R6240 T9346 T9335 auxpass was,reduced
R6241 T9347 T9335 advmod significantly,reduced
R6242 T9348 T9335 punct .,reduced
R6243 T9350 T9351 poss Our,analyses
R6244 T9351 T9353 nsubj analyses,showed
R6245 T9352 T9351 compound footprinting,analyses
R6246 T9354 T9355 mark that,protects
R6247 T9355 T9353 ccomp protects,showed
R6248 T9356 T9355 nsubj Mcm4,protects
R6249 T9357 T9356 punct /,Mcm4
R6250 T9358 T9356 nummod 6,Mcm4
R6251 T9359 T9356 punct /,Mcm4
R6252 T9360 T9356 nummod 7,Mcm4
R6253 T9361 T9355 advmod strongly,protects
R6254 T9362 T9363 nummod 25,nt
R6255 T9363 T9364 nmod nt,segment
R6256 T9364 T9355 dobj segment,protects
R6257 T9365 T9366 amod single,stranded
R6258 T9366 T9364 amod stranded,segment
R6259 T9367 T9366 punct -,stranded
R6260 T9368 T9364 compound DNA,segment
R6261 T9369 T9364 amod adjacent,segment
R6262 T9370 T9369 prep to,adjacent
R6263 T9371 T9372 det each,point
R6264 T9372 T9370 pobj point,to
R6265 T9373 T9372 compound branch,point
R6266 T9374 T9369 cc and,adjacent
R6267 T9375 T9369 conj proximal,adjacent
R6268 T9376 T9375 prep to,proximal
R6269 T9377 T9378 nummod 5,ends
R6270 T9378 T9376 pobj ends,to
R6271 T9379 T9377 punct ′,5
R6272 T9380 T9378 prep of,ends
R6273 T9381 T9382 det both,strands
R6274 T9382 T9380 pobj strands,of
R6275 T9383 T9382 prep of,strands
R6276 T9384 T9385 det the,bubble
R6277 T9385 T9383 pobj bubble,of
R6278 T9386 T9353 punct .,showed
R6279 T9388 T9389 prep At,is
R6280 T9390 T9391 det each,fork
R6281 T9391 T9388 pobj fork,At
R6282 T9392 T9389 punct ", ",is
R6283 T9393 T9394 nummod one,complex
R6284 T9394 T9389 nsubj complex,is
R6285 T9395 T9394 nmod Mcm4,complex
R6286 T9396 T9395 punct /,Mcm4
R6287 T9397 T9395 nummod 6,Mcm4
R6288 T9398 T9395 punct /,Mcm4
R6289 T9399 T9395 nummod 7,Mcm4
R6290 T9400 T9389 acomp likely,is
R6291 T9401 T9402 aux to,encircle
R6292 T9402 T9400 xcomp encircle,likely
R6293 T9403 T9404 det the,strand
R6294 T9404 T9402 dobj strand,encircle
R6295 T9405 T9406 amod single,stranded
R6296 T9406 T9404 amod stranded,strand
R6297 T9407 T9406 punct -,stranded
R6298 T9408 T9404 compound DNA,strand
R6299 T9409 T9389 cc and,is
R6300 T9410 T9411 nummod two,hexamers
R6301 T9411 T9412 nsubj hexamers,bind
R6302 T9412 T9389 conj bind,is
R6303 T9413 T9412 aux may,bind
R6304 T9414 T9412 advmod symmetrically,bind
R6305 T9415 T9412 prep to,bind
R6306 T9416 T9417 det the,substrate
R6307 T9417 T9415 pobj substrate,to
R6308 T9418 T9417 compound bubble,substrate
R6309 T9419 T9412 punct ", ",bind
R6310 T9420 T9412 advcl forming,bind
R6311 T9421 T9422 det a,structure
R6312 T9422 T9420 dobj structure,forming
R6313 T9423 T9424 amod double,hexameric
R6314 T9424 T9422 amod hexameric,structure
R6315 T9425 T9420 prep on,forming
R6316 T9426 T9427 det the,bubble
R6317 T9427 T9425 pobj bubble,on
R6318 T9428 T9429 punct (,see
R6319 T9429 T9420 parataxis see,forming
R6320 T9430 T9431 amod schematic,drawing
R6321 T9431 T9429 dobj drawing,see
R6322 T9432 T9431 prep of,drawing
R6323 T9433 T9434 compound Figure,1A
R6324 T9434 T9432 pobj 1A,of
R6325 T9435 T9429 punct ),see
R6326 T9436 T9412 punct .,bind
R6327 T9438 T9439 amod Efficient,unwinding
R6328 T9439 T9440 nsubj unwinding,require
R6329 T9441 T9439 prep into,unwinding
R6330 T9442 T9443 det both,directions
R6331 T9443 T9441 pobj directions,into
R6332 T9444 T9440 aux may,require
R6333 T9445 T9446 amod simultaneous,activation
R6334 T9446 T9440 dobj activation,require
R6335 T9447 T9446 prep of,activation
R6336 T9448 T9449 det both,hexamers
R6337 T9449 T9447 pobj hexamers,of
R6338 T9450 T9451 dep which,sit
R6339 T9451 T9449 relcl sit,hexamers
R6340 T9452 T9451 aux may,sit
R6341 T9453 T9451 prep at,sit
R6342 T9454 T9455 det the,center
R6343 T9455 T9453 pobj center,at
R6344 T9456 T9457 mark while,extruding
R6345 T9457 T9451 advcl extruding,sit
R6346 T9458 T9459 det the,DNA
R6347 T9459 T9457 dobj DNA,extruding
R6348 T9460 T9459 amod unwound,DNA
R6349 T9461 T9462 amod single,stranded
R6350 T9462 T9459 amod stranded,DNA
R6351 T9463 T9462 punct -,stranded
R6352 T9464 T9457 prep through,extruding
R6353 T9465 T9466 det the,rings
R6354 T9466 T9464 pobj rings,through
R6355 T9467 T9440 punct .,require
R6356 T9469 T9470 nsubj This,resemble
R6357 T9471 T9470 aux may,resemble
R6358 T9472 T9470 advmod closely,resemble
R6359 T9473 T9474 det the,modes
R6360 T9474 T9470 dobj modes,resemble
R6361 T9475 T9474 amod proposed,modes
R6362 T9476 T9474 prep of,modes
R6363 T9477 T9478 nmod binding,actions
R6364 T9478 T9476 pobj actions,of
R6365 T9479 T9477 cc and,binding
R6366 T9480 T9477 conj helicase,binding
R6367 T9481 T9478 prep of,actions
R6368 T9482 T9483 compound T,antigen
R6369 T9483 T9481 pobj antigen,of
R6370 T9484 T9483 punct -,antigen
R6371 T9485 T9486 punct (,21
R6372 T9486 T9470 parataxis 21,resemble
R6373 T9487 T9486 punct ),21
R6374 T9488 T9470 punct .,resemble
R6375 T9490 T9491 mark Although,exclude
R6376 T9491 T9496 advcl exclude,bear
R6377 T9492 T9491 nsubj we,exclude
R6378 T9493 T9491 aux can,exclude
R6379 T9494 T9491 neg not,exclude
R6380 T9495 T9491 advmod totally,exclude
R6381 T9497 T9498 det the,possibility
R6382 T9498 T9491 dobj possibility,exclude
R6383 T9499 T9500 mark that,unwinds
R6384 T9500 T9498 acl unwinds,possibility
R6385 T9501 T9502 nummod one,hexamer
R6386 T9502 T9500 nsubj hexamer,unwinds
R6387 T9503 T9502 nmod Mcm4,hexamer
R6388 T9504 T9503 punct /,Mcm4
R6389 T9505 T9503 nummod 6,Mcm4
R6390 T9506 T9503 punct /,Mcm4
R6391 T9507 T9503 nummod 7,Mcm4
R6392 T9508 T9502 prep at,hexamer
R6393 T9509 T9510 det each,fork
R6394 T9510 T9508 pobj fork,at
R6395 T9511 T9512 det the,duplex
R6396 T9512 T9500 dobj duplex,unwinds
R6397 T9513 T9500 advmod independently,unwinds
R6398 T9514 T9496 punct ", ",bear
R6399 T9515 T9516 npadvmod ring,shaped
R6400 T9516 T9518 amod shaped,structures
R6401 T9517 T9516 punct -,shaped
R6402 T9518 T9496 nsubj structures,bear
R6403 T9519 T9518 prep of,structures
R6404 T9520 T9521 nmod mouse,MCM
R6405 T9521 T9519 pobj MCM,of
R6406 T9522 T9520 cc and,mouse
R6407 T9523 T9520 conj archea,mouse
R6408 T9524 T9496 punct ", ",bear
R6409 T9525 T9526 mark as,revealed
R6410 T9526 T9496 advcl revealed,bear
R6411 T9527 T9526 agent by,revealed
R6412 T9528 T9529 compound electron,microscopy
R6413 T9529 T9527 pobj microscopy,by
R6414 T9530 T9496 punct ", ",bear
R6415 T9531 T9532 amod much,similarity
R6416 T9532 T9496 dobj similarity,bear
R6417 T9533 T9532 prep to,similarity
R6418 T9534 T9535 det the,structure
R6419 T9535 T9533 pobj structure,to
R6420 T9536 T9537 advmod recently,solved
R6421 T9537 T9535 amod solved,structure
R6422 T9538 T9535 prep of,structure
R6423 T9539 T9540 det the,antigen
R6424 T9540 T9538 pobj antigen,of
R6425 T9541 T9540 nmod SV40,antigen
R6426 T9542 T9540 amod large,antigen
R6427 T9543 T9540 compound T,antigen
R6428 T9544 T9540 punct -,antigen
R6429 T9545 T9546 punct (,6
R6430 T9546 T9535 parataxis 6,structure
R6431 T9547 T9546 nummod 4,6
R6432 T9548 T9546 punct ",",6
R6433 T9549 T9546 punct ),6
R6434 T9550 T9496 punct ", ",bear
R6435 T9551 T9496 cc and,bear
R6436 T9552 T9496 conj are,bear
R6437 T9553 T9552 prep in,are
R6438 T9554 T9553 pobj favor,in
R6439 T9555 T9554 prep of,favor
R6440 T9556 T9557 det the,structure
R6441 T9557 T9555 pobj structure,of
R6442 T9558 T9559 amod double,hexameric
R6443 T9559 T9557 amod hexameric,structure
R6444 T9560 T9559 punct -,hexameric
R6445 T9561 T9557 prep of,structure
R6446 T9562 T9563 compound mouse,Mcm
R6447 T9563 T9561 pobj Mcm,of
R6448 T9564 T9557 prep on,structure
R6449 T9565 T9566 det a,DNA
R6450 T9566 T9564 pobj DNA,on
R6451 T9567 T9566 compound bubble,DNA
R6452 T9568 T9496 punct .,bear

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T9008 9-16 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T9009 35-39 PR_EXT:000010246 denotes Mcm4
T9010 35-43 GO:0097373 denotes Mcm4/6/7
T9011 44-52 GO_EXT:0004386 denotes helicase
T9012 75-104 GO:0006270 denotes Initiation of DNA replication
T9013 89-92 CHEBI_SO_EXT:DNA denotes DNA
T9014 124-133 GO_PATO_EXT:biological_localization_process_or_quality denotes localized
T9015 134-155 GO:0032508 denotes melting of duplex DNA
T9016 145-155 CHEBI_SO_EXT:double_stranded_DNA denotes duplex DNA
T9017 161-172 GO:0006260 denotes replication
T9018 161-180 SO_EXT:0000296 denotes replication origins
T9019 182-191 GO_EXT:0004386 denotes Helicases
T9020 208-219 GO:0006260 denotes replication
T9021 208-225 GO:0005657 denotes replication forks
T9022 238-244 GO:0032508 denotes melted
T9023 274-281 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T9024 286-294 NCBITaxon:2 denotes bacteria
T9025 329-333 PR_EXT:000010246 denotes Mcm4
T9026 329-337 GO:0097373 denotes Mcm4/6/7
T9027 400-403 CHEBI_SO_EXT:DNA denotes DNA
T9028 400-412 GO_EXT:0003678 denotes DNA helicase
T9029 420-425 GO:0005657 denotes forks
T9030 447-451 PR_EXT:000010246 denotes Mcm4
T9031 447-455 GO:0097373 denotes Mcm4/6/7
T9032 512-522 CHEBI_SO_EXT:double_stranded_DNA denotes duplex DNA
T9033 557-560 GO:0042555 denotes Mcm
T9034 587-602 SO:0000984 denotes single-stranded
T9035 643-647 PR_EXT:000010246 denotes Mcm4
T9036 643-659 GO:0097373 denotes Mcm4/6/7 complex
T9037 691-698 CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group denotes thymine
T9038 704-713 SO_EXT:biological_sequence denotes sequences
T9039 725-740 SO:0000984 denotes single-stranded
T9040 753-761 GO_EXT:0004386 denotes helicase
T9041 820-828 GO_EXT:0004386 denotes helicase
T9042 839-843 PR_EXT:000010246 denotes Mcm4
T9043 839-847 GO:0097373 denotes Mcm4/6/7
T9044 902-910 SO:0000984 denotes unpaired
T9045 952-954 CHEBI_SO_EXT:nucleotide denotes nt
T9047 974-985,1005-1012 GO:0065003 denotes assembly of complex
T9048 988-1012 GO_EXT:double_hexameric_macromolecular_complex denotes double-hexameric complex
T9049 1030-1033 CHEBI_SO_EXT:DNA denotes DNA
T9050 1046-1050 NCBITaxon:10633 denotes SV40
T9051 1053-1060 CHEBI_EXT:59132 denotes antigen
T9052 1061-1068 CHEBI_PR_EXT:protein denotes protein
T9053 1110-1125 SO:0000984 denotes single-stranded
T9054 1137-1138 CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group denotes T
T9055 1155-1163 SO_EXT:sequence_substitution_process denotes replaced
T9056 1167-1174 CHEBI_EXT:guanine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group denotes guanine
T9057 1180-1189 SO_EXT:biological_sequence denotes sequences
T9058 1284-1288 PR_EXT:000010246 denotes Mcm4
T9059 1284-1292 GO:0097373 denotes Mcm4/6/7
T9060 1314-1316 CHEBI_SO_EXT:nucleotide denotes nt
T9061 1317-1336 CHEBI_SO_EXT:single_stranded_DNA denotes single-stranded DNA
T9062 1438-1442 GO:0005657 denotes fork
T9063 1448-1452 PR_EXT:000010246 denotes Mcm4
T9064 1448-1464 GO:0097373 denotes Mcm4/6/7 complex
T9065 1491-1510 CHEBI_SO_EXT:single_stranded_DNA denotes single-stranded DNA
T9066 1526-1534 GO_EXT:hexameric_macromolecular_complex denotes hexamers
T9067 1539-1543 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes bind
T9068 1593-1609 GO_EXT:double_hexameric_macromolecular_complex denotes double hexameric
T9069 1757-1765 GO_EXT:hexameric_macromolecular_complex denotes hexamers
T9070 1822-1841 CHEBI_SO_EXT:single_stranded_DNA denotes single-stranded DNA
T9071 1909-1916 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T9072 1921-1929 GO_EXT:0004386 denotes helicase
T9073 1943-1950 CHEBI_EXT:59132 denotes antigen
T9074 2017-2021 PR_EXT:000010246 denotes Mcm4
T9075 2017-2025 GO:0097373 denotes Mcm4/6/7
T9076 2026-2033 GO_EXT:hexameric_macromolecular_complex denotes hexamer
T9077 2042-2046 GO:0005657 denotes fork
T9078 2107-2112 NCBITaxon:10088 denotes mouse
T9079 2117-2123 NCBITaxon:2157 denotes archea
T9080 2124-2127 GO:0042555 denotes MCM
T9081 2144-2152 CHEBI:10545 denotes electron
T9082 2226-2230 NCBITaxon:10633 denotes SV40
T9083 2239-2246 CHEBI_EXT:59132 denotes antigen
T9084 2278-2294 GO_EXT:double_hexameric_macromolecular_complex denotes double-hexameric
T9085 2308-2313 NCBITaxon:10088 denotes mouse
T9086 2314-2317 GO:0042555 denotes Mcm
T9087 2330-2333 CHEBI_SO_EXT:DNA denotes DNA

craft-ca-core-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T8958 35-39 PR:000010246 denotes Mcm4
T8959 35-43 GO:0097373 denotes Mcm4/6/7
T8960 75-104 GO:0006270 denotes Initiation of DNA replication
T8961 134-155 GO:0032508 denotes melting of duplex DNA
T8962 145-151 SO:0000985 denotes duplex
T8963 161-172 GO:0006260 denotes replication
T8964 161-180 SO:0000296 denotes replication origins
T8965 208-219 GO:0006260 denotes replication
T8966 208-225 GO:0005657 denotes replication forks
T8967 238-244 GO:0032508 denotes melted
T8968 286-294 NCBITaxon:2 denotes bacteria
T8969 329-333 PR:000010246 denotes Mcm4
T8970 329-337 GO:0097373 denotes Mcm4/6/7
T8971 420-425 GO:0005657 denotes forks
T8972 447-451 PR:000010246 denotes Mcm4
T8973 447-455 GO:0097373 denotes Mcm4/6/7
T8974 512-518 SO:0000985 denotes duplex
T8975 557-560 GO:0042555 denotes Mcm
T8976 587-602 SO:0000984 denotes single-stranded
T8977 643-647 PR:000010246 denotes Mcm4
T8978 643-659 GO:0097373 denotes Mcm4/6/7 complex
T8979 725-740 SO:0000984 denotes single-stranded
T8980 839-843 PR:000010246 denotes Mcm4
T8981 839-847 GO:0097373 denotes Mcm4/6/7
T8982 902-910 SO:0000984 denotes unpaired
T8984 974-985,1005-1012 GO:0065003 denotes assembly of complex
T8985 1046-1050 NCBITaxon:10633 denotes SV40
T8986 1053-1060 CHEBI:59132 denotes antigen
T8987 1110-1125 SO:0000984 denotes single-stranded
T8988 1284-1288 PR:000010246 denotes Mcm4
T8989 1284-1292 GO:0097373 denotes Mcm4/6/7
T8990 1317-1332 SO:0000984 denotes single-stranded
T8991 1438-1442 GO:0005657 denotes fork
T8992 1448-1452 PR:000010246 denotes Mcm4
T8993 1448-1464 GO:0097373 denotes Mcm4/6/7 complex
T8994 1491-1506 SO:0000984 denotes single-stranded
T8995 1822-1837 SO:0000984 denotes single-stranded
T8996 1943-1950 CHEBI:59132 denotes antigen
T8997 2017-2021 PR:000010246 denotes Mcm4
T8998 2017-2025 GO:0097373 denotes Mcm4/6/7
T8999 2042-2046 GO:0005657 denotes fork
T9000 2107-2112 NCBITaxon:10088 denotes mouse
T9001 2117-2123 NCBITaxon:2157 denotes archea
T9002 2124-2127 GO:0042555 denotes MCM
T9003 2144-2152 CHEBI:10545 denotes electron
T9004 2226-2230 NCBITaxon:10633 denotes SV40
T9005 2239-2246 CHEBI:59132 denotes antigen
T9006 2308-2313 NCBITaxon:10088 denotes mouse
T9007 2314-2317 GO:0042555 denotes Mcm

2_test

Id Subject Object Predicate Lexical cue
15917436-2843291-76775532 296-298 2843291 denotes 32
15917436-14609960-76775533 427-429 14609960 denotes 13
15917436-14609960-76775534 774-776 14609960 denotes 13
15917436-9765408-76775535 1082-1084 9765408 denotes 21
15917436-9765408-76775536 1952-1954 9765408 denotes 21
15917436-14566326-76775537 2248-2249 14566326 denotes 4
15917436-12774115-76775538 2250-2251 12774115 denotes 6