PMC:1140370 / 21947-22221
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1140370","sourcedb":"PMC","sourceid":"1140370","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1140370","text":" Partial heteroduplex substrates containing the 3′-tail of TC25, TTCC13, TTTCCC8, TTTTCCCC6, TTCC17 were displaced by the Mcm4/6/7 complex to the extent similar to that achieved by TTA17, suggesting that 50% thymine content is sufficient for full activation of Mcm helicase.","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T6693","span":{"begin":0,"end":274},"obj":"sentence"},{"id":"T6694","span":{"begin":1,"end":8},"obj":"JJ"},{"id":"T6695","span":{"begin":22,"end":32},"obj":"NNS"},{"id":"T6696","span":{"begin":9,"end":21},"obj":"NN"},{"id":"T6697","span":{"begin":105,"end":114},"obj":"VBN"},{"id":"T6698","span":{"begin":33,"end":43},"obj":"VBG"},{"id":"T6699","span":{"begin":44,"end":47},"obj":"DT"},{"id":"T6700","span":{"begin":51,"end":55},"obj":"NN"},{"id":"T6701","span":{"begin":48,"end":49},"obj":"CD"},{"id":"T6702","span":{"begin":49,"end":50},"obj":"SYM"},{"id":"T6703","span":{"begin":50,"end":51},"obj":"HYPH"},{"id":"T6704","span":{"begin":56,"end":58},"obj":"IN"},{"id":"T6705","span":{"begin":59,"end":63},"obj":"NN"},{"id":"T6706","span":{"begin":93,"end":99},"obj":"NN"},{"id":"T6707","span":{"begin":63,"end":65},"obj":","},{"id":"T6708","span":{"begin":65,"end":71},"obj":"NN"},{"id":"T6709","span":{"begin":71,"end":73},"obj":","},{"id":"T6710","span":{"begin":73,"end":80},"obj":"NN"},{"id":"T6711","span":{"begin":80,"end":82},"obj":","},{"id":"T6712","span":{"begin":82,"end":91},"obj":"NN"},{"id":"T6713","span":{"begin":91,"end":93},"obj":","},{"id":"T6714","span":{"begin":100,"end":104},"obj":"VBD"},{"id":"T6715","span":{"begin":115,"end":117},"obj":"IN"},{"id":"T6716","span":{"begin":118,"end":121},"obj":"DT"},{"id":"T6717","span":{"begin":131,"end":138},"obj":"NN"},{"id":"T6718","span":{"begin":122,"end":126},"obj":"NN"},{"id":"T6719","span":{"begin":126,"end":127},"obj":"HYPH"},{"id":"T6720","span":{"begin":127,"end":128},"obj":"CD"},{"id":"T6721","span":{"begin":128,"end":129},"obj":"HYPH"},{"id":"T6722","span":{"begin":129,"end":130},"obj":"CD"},{"id":"T6723","span":{"begin":139,"end":141},"obj":"IN"},{"id":"T6724","span":{"begin":142,"end":145},"obj":"DT"},{"id":"T6725","span":{"begin":146,"end":152},"obj":"NN"},{"id":"T6726","span":{"begin":153,"end":160},"obj":"JJ"},{"id":"T6727","span":{"begin":161,"end":163},"obj":"IN"},{"id":"T6728","span":{"begin":164,"end":168},"obj":"DT"},{"id":"T6729","span":{"begin":169,"end":177},"obj":"VBN"},{"id":"T6730","span":{"begin":178,"end":180},"obj":"IN"},{"id":"T6731","span":{"begin":181,"end":186},"obj":"NN"},{"id":"T6732","span":{"begin":186,"end":188},"obj":","},{"id":"T6733","span":{"begin":188,"end":198},"obj":"VBG"},{"id":"T6734","span":{"begin":199,"end":203},"obj":"IN"},{"id":"T6735","span":{"begin":224,"end":226},"obj":"VBZ"},{"id":"T6736","span":{"begin":204,"end":206},"obj":"CD"},{"id":"T6737","span":{"begin":206,"end":207},"obj":"NN"},{"id":"T6738","span":{"begin":216,"end":223},"obj":"NN"},{"id":"T6739","span":{"begin":208,"end":215},"obj":"NN"},{"id":"T6740","span":{"begin":227,"end":237},"obj":"JJ"},{"id":"T6741","span":{"begin":238,"end":241},"obj":"IN"},{"id":"T6742","span":{"begin":242,"end":246},"obj":"JJ"},{"id":"T6743","span":{"begin":247,"end":257},"obj":"NN"},{"id":"T6744","span":{"begin":258,"end":260},"obj":"IN"},{"id":"T6745","span":{"begin":261,"end":264},"obj":"NN"},{"id":"T6746","span":{"begin":265,"end":273},"obj":"NN"},{"id":"T6747","span":{"begin":273,"end":274},"obj":"."}],"relations":[{"id":"R4575","pred":"amod","subj":"T6694","obj":"T6695"},{"id":"R4576","pred":"nsubjpass","subj":"T6695","obj":"T6697"},{"id":"R4577","pred":"compound","subj":"T6696","obj":"T6695"},{"id":"R4578","pred":"acl","subj":"T6698","obj":"T6695"},{"id":"R4579","pred":"det","subj":"T6699","obj":"T6700"},{"id":"R4580","pred":"dobj","subj":"T6700","obj":"T6698"},{"id":"R4581","pred":"nummod","subj":"T6701","obj":"T6700"},{"id":"R4582","pred":"punct","subj":"T6702","obj":"T6701"},{"id":"R4583","pred":"punct","subj":"T6703","obj":"T6700"},{"id":"R4584","pred":"prep","subj":"T6704","obj":"T6700"},{"id":"R4585","pred":"nmod","subj":"T6705","obj":"T6706"},{"id":"R4586","pred":"pobj","subj":"T6706","obj":"T6704"},{"id":"R4587","pred":"punct","subj":"T6707","obj":"T6706"},{"id":"R4588","pred":"nmod","subj":"T6708","obj":"T6706"},{"id":"R4589","pred":"punct","subj":"T6709","obj":"T6706"},{"id":"R4590","pred":"nmod","subj":"T6710","obj":"T6706"},{"id":"R4591","pred":"punct","subj":"T6711","obj":"T6706"},{"id":"R4592","pred":"nmod","subj":"T6712","obj":"T6706"},{"id":"R4593","pred":"punct","subj":"T6713","obj":"T6706"},{"id":"R4594","pred":"auxpass","subj":"T6714","obj":"T6697"},{"id":"R4595","pred":"agent","subj":"T6715","obj":"T6697"},{"id":"R4596","pred":"det","subj":"T6716","obj":"T6717"},{"id":"R4597","pred":"pobj","subj":"T6717","obj":"T6715"},{"id":"R4598","pred":"nmod","subj":"T6718","obj":"T6717"},{"id":"R4599","pred":"punct","subj":"T6719","obj":"T6718"},{"id":"R4600","pred":"nummod","subj":"T6720","obj":"T6718"},{"id":"R4601","pred":"punct","subj":"T6721","obj":"T6718"},{"id":"R4602","pred":"nummod","subj":"T6722","obj":"T6718"},{"id":"R4603","pred":"prep","subj":"T6723","obj":"T6697"},{"id":"R4604","pred":"det","subj":"T6724","obj":"T6725"},{"id":"R4605","pred":"pobj","subj":"T6725","obj":"T6723"},{"id":"R4606","pred":"amod","subj":"T6726","obj":"T6725"},{"id":"R4607","pred":"prep","subj":"T6727","obj":"T6726"},{"id":"R4608","pred":"pobj","subj":"T6728","obj":"T6727"},{"id":"R4609","pred":"acl","subj":"T6729","obj":"T6728"},{"id":"R4610","pred":"agent","subj":"T6730","obj":"T6729"},{"id":"R4611","pred":"pobj","subj":"T6731","obj":"T6730"},{"id":"R4612","pred":"punct","subj":"T6732","obj":"T6697"},{"id":"R4613","pred":"advcl","subj":"T6733","obj":"T6697"},{"id":"R4614","pred":"mark","subj":"T6734","obj":"T6735"},{"id":"R4615","pred":"ccomp","subj":"T6735","obj":"T6733"},{"id":"R4616","pred":"nummod","subj":"T6736","obj":"T6737"},{"id":"R4617","pred":"compound","subj":"T6737","obj":"T6738"},{"id":"R4618","pred":"nsubj","subj":"T6738","obj":"T6735"},{"id":"R4619","pred":"compound","subj":"T6739","obj":"T6738"},{"id":"R4620","pred":"acomp","subj":"T6740","obj":"T6735"},{"id":"R4621","pred":"prep","subj":"T6741","obj":"T6740"},{"id":"R4622","pred":"amod","subj":"T6742","obj":"T6743"},{"id":"R4623","pred":"pobj","subj":"T6743","obj":"T6741"},{"id":"R4624","pred":"prep","subj":"T6744","obj":"T6743"},{"id":"R4625","pred":"compound","subj":"T6745","obj":"T6746"},{"id":"R4626","pred":"pobj","subj":"T6746","obj":"T6744"},{"id":"R4627","pred":"punct","subj":"T6747","obj":"T6697"}],"attributes":[{"subj":"T6693","pred":"source","obj":"craft-sa-dev"},{"subj":"T6694","pred":"source","obj":"craft-sa-dev"},{"subj":"T6695","pred":"source","obj":"craft-sa-dev"},{"subj":"T6696","pred":"source","obj":"craft-sa-dev"},{"subj":"T6697","pred":"source","obj":"craft-sa-dev"},{"subj":"T6698","pred":"source","obj":"craft-sa-dev"},{"subj":"T6699","pred":"source","obj":"craft-sa-dev"},{"subj":"T6700","pred":"source","obj":"craft-sa-dev"},{"subj":"T6701","pred":"source","obj":"craft-sa-dev"},{"subj":"T6702","pred":"source","obj":"craft-sa-dev"},{"subj":"T6703","pred":"source","obj":"craft-sa-dev"},{"subj":"T6704","pred":"source","obj":"craft-sa-dev"},{"subj":"T6705","pred":"source","obj":"craft-sa-dev"},{"subj":"T6706","pred":"source","obj":"craft-sa-dev"},{"subj":"T6707","pred":"source","obj":"craft-sa-dev"},{"subj":"T6708","pred":"source","obj":"craft-sa-dev"},{"subj":"T6709","pred":"source","obj":"craft-sa-dev"},{"subj":"T6710","pred":"source","obj":"craft-sa-dev"},{"subj":"T6711","pred":"source","obj":"craft-sa-dev"},{"subj":"T6712","pred":"source","obj":"craft-sa-dev"},{"subj":"T6713","pred":"source","obj":"craft-sa-dev"},{"subj":"T6714","pred":"source","obj":"craft-sa-dev"},{"subj":"T6715","pred":"source","obj":"craft-sa-dev"},{"subj":"T6716","pred":"source","obj":"craft-sa-dev"},{"subj":"T6717","pred":"source","obj":"craft-sa-dev"},{"subj":"T6718","pred":"source","obj":"craft-sa-dev"},{"subj":"T6719","pred":"source","obj":"craft-sa-dev"},{"subj":"T6720","pred":"source","obj":"craft-sa-dev"},{"subj":"T6721","pred":"source","obj":"craft-sa-dev"},{"subj":"T6722","pred":"source","obj":"craft-sa-dev"},{"subj":"T6723","pred":"source","obj":"craft-sa-dev"},{"subj":"T6724","pred":"source","obj":"craft-sa-dev"},{"subj":"T6725","pred":"source","obj":"craft-sa-dev"},{"subj":"T6726","pred":"source","obj":"craft-sa-dev"},{"subj":"T6727","pred":"source","obj":"craft-sa-dev"},{"subj":"T6728","pred":"source","obj":"craft-sa-dev"},{"subj":"T6729","pred":"source","obj":"craft-sa-dev"},{"subj":"T6730","pred":"source","obj":"craft-sa-dev"},{"subj":"T6731","pred":"source","obj":"craft-sa-dev"},{"subj":"T6732","pred":"source","obj":"craft-sa-dev"},{"subj":"T6733","pred":"source","obj":"craft-sa-dev"},{"subj":"T6734","pred":"source","obj":"craft-sa-dev"},{"subj":"T6735","pred":"source","obj":"craft-sa-dev"},{"subj":"T6736","pred":"source","obj":"craft-sa-dev"},{"subj":"T6737","pred":"source","obj":"craft-sa-dev"},{"subj":"T6738","pred":"source","obj":"craft-sa-dev"},{"subj":"T6739","pred":"source","obj":"craft-sa-dev"},{"subj":"T6740","pred":"source","obj":"craft-sa-dev"},{"subj":"T6741","pred":"source","obj":"craft-sa-dev"},{"subj":"T6742","pred":"source","obj":"craft-sa-dev"},{"subj":"T6743","pred":"source","obj":"craft-sa-dev"},{"subj":"T6744","pred":"source","obj":"craft-sa-dev"},{"subj":"T6745","pred":"source","obj":"craft-sa-dev"},{"subj":"T6746","pred":"source","obj":"craft-sa-dev"},{"subj":"T6747","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T6393","span":{"begin":15,"end":21},"obj":"SO:0000985"},{"id":"T6394","span":{"begin":122,"end":126},"obj":"PR_EXT:000010246"},{"id":"T6395","span":{"begin":122,"end":138},"obj":"GO:0097373"},{"id":"T6396","span":{"begin":208,"end":215},"obj":"CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group"},{"id":"T6397","span":{"begin":261,"end":264},"obj":"GO:0042555"},{"id":"T6398","span":{"begin":265,"end":273},"obj":"GO_EXT:0004386"}],"attributes":[{"subj":"T6393","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6394","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6395","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6396","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6397","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6398","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T6352","span":{"begin":15,"end":21},"obj":"SO:0000985"},{"id":"T6353","span":{"begin":122,"end":126},"obj":"PR:000010246"},{"id":"T6354","span":{"begin":122,"end":138},"obj":"GO:0097373"},{"id":"T6355","span":{"begin":261,"end":264},"obj":"GO:0042555"}],"attributes":[{"subj":"T6352","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T6353","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T6354","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T6355","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#c693ec","default":true},{"id":"craft-ca-core-ex-dev","color":"#93ecac"},{"id":"craft-ca-core-dev","color":"#ec9393"}]}]}}