PMC:1140370 / 1391-1699 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1140370","sourcedb":"PMC","sourceid":"1140370","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1140370","text":"en together, these findings reveal important features on activation and substrate preference of the eukaryotic replicative helicase.\n\nINTRODUCTION\nDNA helicases couple the hydrolysis of nucleotide or deoxynucleotide triphosphate to duplex unwinding (1). Coordination of a set of subactivities including nucle","divisions":[{"label":"title","span":{"begin":134,"end":146}}],"tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T418","span":{"begin":28,"end":34},"obj":"VBP"},{"id":"T419","span":{"begin":3,"end":11},"obj":"RB"},{"id":"T420","span":{"begin":11,"end":13},"obj":","},{"id":"T421","span":{"begin":13,"end":18},"obj":"DT"},{"id":"T422","span":{"begin":19,"end":27},"obj":"NNS"},{"id":"T423","span":{"begin":35,"end":44},"obj":"JJ"},{"id":"T424","span":{"begin":45,"end":53},"obj":"NNS"},{"id":"T425","span":{"begin":54,"end":56},"obj":"IN"},{"id":"T426","span":{"begin":57,"end":67},"obj":"NN"},{"id":"T427","span":{"begin":82,"end":92},"obj":"NN"},{"id":"T428","span":{"begin":68,"end":71},"obj":"CC"},{"id":"T429","span":{"begin":72,"end":81},"obj":"NN"},{"id":"T430","span":{"begin":93,"end":95},"obj":"IN"},{"id":"T431","span":{"begin":96,"end":99},"obj":"DT"},{"id":"T432","span":{"begin":123,"end":131},"obj":"NN"},{"id":"T433","span":{"begin":100,"end":110},"obj":"JJ"},{"id":"T434","span":{"begin":111,"end":122},"obj":"JJ"},{"id":"T435","span":{"begin":131,"end":132},"obj":"."},{"id":"T757","span":{"begin":147,"end":150},"obj":"NN"},{"id":"T758","span":{"begin":151,"end":160},"obj":"NNS"},{"id":"T759","span":{"begin":161,"end":167},"obj":"VBP"},{"id":"T760","span":{"begin":168,"end":171},"obj":"DT"},{"id":"T761","span":{"begin":172,"end":182},"obj":"NN"},{"id":"T762","span":{"begin":183,"end":185},"obj":"IN"},{"id":"T763","span":{"begin":186,"end":196},"obj":"NN"},{"id":"T764","span":{"begin":216,"end":228},"obj":"NN"},{"id":"T765","span":{"begin":197,"end":199},"obj":"CC"},{"id":"T766","span":{"begin":200,"end":215},"obj":"NN"},{"id":"T767","span":{"begin":229,"end":231},"obj":"IN"},{"id":"T768","span":{"begin":232,"end":238},"obj":"NN"},{"id":"T769","span":{"begin":239,"end":248},"obj":"NN"},{"id":"T770","span":{"begin":249,"end":250},"obj":"-LRB-"},{"id":"T771","span":{"begin":250,"end":251},"obj":"CD"},{"id":"T772","span":{"begin":251,"end":252},"obj":"-RRB-"},{"id":"T773","span":{"begin":252,"end":253},"obj":"."},{"id":"T775","span":{"begin":254,"end":266},"obj":"NN"},{"id":"T777","span":{"begin":267,"end":269},"obj":"IN"},{"id":"T778","span":{"begin":270,"end":271},"obj":"DT"},{"id":"T779","span":{"begin":272,"end":275},"obj":"NN"},{"id":"T780","span":{"begin":276,"end":278},"obj":"IN"},{"id":"T781","span":{"begin":279,"end":292},"obj":"NNS"},{"id":"T782","span":{"begin":293,"end":302},"obj":"VBG"}],"relations":[{"id":"R243","pred":"punct","subj":"T420","obj":"T418"},{"id":"R244","pred":"det","subj":"T421","obj":"T422"},{"id":"R246","pred":"nsubj","subj":"T422","obj":"T418"},{"id":"R247","pred":"amod","subj":"T423","obj":"T424"},{"id":"R248","pred":"dobj","subj":"T424","obj":"T418"},{"id":"R250","pred":"prep","subj":"T425","obj":"T424"},{"id":"R252","pred":"nmod","subj":"T426","obj":"T427"},{"id":"R253","pred":"pobj","subj":"T427","obj":"T425"},{"id":"R254","pred":"cc","subj":"T428","obj":"T426"},{"id":"R256","pred":"conj","subj":"T429","obj":"T426"},{"id":"R257","pred":"prep","subj":"T430","obj":"T427"},{"id":"R259","pred":"det","subj":"T431","obj":"T432"},{"id":"R260","pred":"pobj","subj":"T432","obj":"T430"},{"id":"R262","pred":"amod","subj":"T433","obj":"T432"},{"id":"R263","pred":"amod","subj":"T434","obj":"T432"},{"id":"R264","pred":"punct","subj":"T435","obj":"T418"},{"id":"R278","pred":"compound","subj":"T757","obj":"T758"},{"id":"R279","pred":"nsubj","subj":"T758","obj":"T759"},{"id":"R280","pred":"det","subj":"T760","obj":"T761"},{"id":"R281","pred":"dobj","subj":"T761","obj":"T759"},{"id":"R282","pred":"prep","subj":"T762","obj":"T761"},{"id":"R283","pred":"nmod","subj":"T763","obj":"T764"},{"id":"R284","pred":"pobj","subj":"T764","obj":"T762"},{"id":"R285","pred":"cc","subj":"T765","obj":"T763"},{"id":"R286","pred":"conj","subj":"T766","obj":"T763"},{"id":"R287","pred":"prep","subj":"T767","obj":"T759"},{"id":"R288","pred":"compound","subj":"T768","obj":"T769"},{"id":"R289","pred":"pobj","subj":"T769","obj":"T767"},{"id":"R290","pred":"punct","subj":"T770","obj":"T771"},{"id":"R291","pred":"parataxis","subj":"T771","obj":"T759"},{"id":"R292","pred":"punct","subj":"T772","obj":"T771"},{"id":"R293","pred":"punct","subj":"T773","obj":"T759"},{"id":"R295","pred":"prep","subj":"T777","obj":"T775"},{"id":"R296","pred":"det","subj":"T778","obj":"T779"},{"id":"R297","pred":"pobj","subj":"T779","obj":"T777"},{"id":"R298","pred":"prep","subj":"T780","obj":"T779"},{"id":"R299","pred":"pobj","subj":"T781","obj":"T780"},{"id":"R300","pred":"prep","subj":"T782","obj":"T781"}],"attributes":[{"subj":"T418","pred":"source","obj":"craft-sa-dev"},{"subj":"T419","pred":"source","obj":"craft-sa-dev"},{"subj":"T420","pred":"source","obj":"craft-sa-dev"},{"subj":"T421","pred":"source","obj":"craft-sa-dev"},{"subj":"T422","pred":"source","obj":"craft-sa-dev"},{"subj":"T423","pred":"source","obj":"craft-sa-dev"},{"subj":"T424","pred":"source","obj":"craft-sa-dev"},{"subj":"T425","pred":"source","obj":"craft-sa-dev"},{"subj":"T426","pred":"source","obj":"craft-sa-dev"},{"subj":"T427","pred":"source","obj":"craft-sa-dev"},{"subj":"T428","pred":"source","obj":"craft-sa-dev"},{"subj":"T429","pred":"source","obj":"craft-sa-dev"},{"subj":"T430","pred":"source","obj":"craft-sa-dev"},{"subj":"T431","pred":"source","obj":"craft-sa-dev"},{"subj":"T432","pred":"source","obj":"craft-sa-dev"},{"subj":"T433","pred":"source","obj":"craft-sa-dev"},{"subj":"T434","pred":"source","obj":"craft-sa-dev"},{"subj":"T435","pred":"source","obj":"craft-sa-dev"},{"subj":"T757","pred":"source","obj":"craft-sa-dev"},{"subj":"T758","pred":"source","obj":"craft-sa-dev"},{"subj":"T759","pred":"source","obj":"craft-sa-dev"},{"subj":"T760","pred":"source","obj":"craft-sa-dev"},{"subj":"T761","pred":"source","obj":"craft-sa-dev"},{"subj":"T762","pred":"source","obj":"craft-sa-dev"},{"subj":"T763","pred":"source","obj":"craft-sa-dev"},{"subj":"T764","pred":"source","obj":"craft-sa-dev"},{"subj":"T765","pred":"source","obj":"craft-sa-dev"},{"subj":"T766","pred":"source","obj":"craft-sa-dev"},{"subj":"T767","pred":"source","obj":"craft-sa-dev"},{"subj":"T768","pred":"source","obj":"craft-sa-dev"},{"subj":"T769","pred":"source","obj":"craft-sa-dev"},{"subj":"T770","pred":"source","obj":"craft-sa-dev"},{"subj":"T771","pred":"source","obj":"craft-sa-dev"},{"subj":"T772","pred":"source","obj":"craft-sa-dev"},{"subj":"T773","pred":"source","obj":"craft-sa-dev"},{"subj":"T775","pred":"source","obj":"craft-sa-dev"},{"subj":"T777","pred":"source","obj":"craft-sa-dev"},{"subj":"T778","pred":"source","obj":"craft-sa-dev"},{"subj":"T779","pred":"source","obj":"craft-sa-dev"},{"subj":"T780","pred":"source","obj":"craft-sa-dev"},{"subj":"T781","pred":"source","obj":"craft-sa-dev"},{"subj":"T782","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T139","span":{"begin":100,"end":110},"obj":"NCBITaxon:2759"},{"id":"T140","span":{"begin":111,"end":122},"obj":"GO:0006260"},{"id":"T141","span":{"begin":123,"end":131},"obj":"GO_EXT:0004386"},{"id":"T623","span":{"begin":147,"end":150},"obj":"CHEBI_SO_EXT:DNA"},{"id":"T624","span":{"begin":147,"end":160},"obj":"GO_EXT:0003678"},{"id":"T625","span":{"begin":172,"end":182},"obj":"MOP:0000619"},{"id":"T626","span":{"begin":186,"end":196},"obj":"_FRAGMENT"},{"id":"T627","span":{"begin":216,"end":228},"obj":"CHEBI_EXT:nucleotide_triphosphate"},{"id":"T628","span":{"begin":200,"end":228},"obj":"CHEBI_EXT:dNTP"},{"id":"T629","span":{"begin":232,"end":248},"obj":"GO:0032508"}],"relations":[{"id":"R276","pred":"_lexicallyChainedTo","subj":"T627","obj":"T626"}],"attributes":[{"subj":"T139","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T140","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T141","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T623","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T624","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T625","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T626","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T627","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T628","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T629","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T81","span":{"begin":100,"end":110},"obj":"NCBITaxon:2759"},{"id":"T82","span":{"begin":111,"end":122},"obj":"GO:0006260"},{"id":"T547","span":{"begin":172,"end":182},"obj":"MOP:0000619"},{"id":"T548","span":{"begin":232,"end":248},"obj":"GO:0032508"}],"attributes":[{"subj":"T81","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T82","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T547","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T548","pred":"source","obj":"craft-ca-core-dev"}]},{"project":"2_test","denotations":[{"id":"15917436-10966472-76775476","span":{"begin":250,"end":251},"obj":"10966472"}],"attributes":[{"subj":"15917436-10966472-76775476","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#d7ec93","default":true},{"id":"craft-ca-core-ex-dev","color":"#e693ec"},{"id":"craft-ca-core-dev","color":"#93eccc"},{"id":"2_test","color":"#ecb293"}]}]}}