PMC:1087847 / 29514-30940 JSONTXT

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One function of Annexin A2 in the nucleus, that appears not to involve binding of p11, has been suggested by its purification as part of a primer recognition protein complex that enhances DNA polymeraseα-activity in vitro [34]. The annexins may participate in a nuclear response to initial cell stimulation or to a Ca2+-transient, presumably by regulating DNA replication. For Annexin A7 such a pathway is very speculative at the moment. 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