Id |
Subject |
Object |
Predicate |
Lexical cue |
T6734 |
0-2 |
IN |
denotes |
In |
T6735 |
32-40 |
VBD |
denotes |
observed |
T6736 |
3-6 |
DT |
denotes |
the |
T6737 |
13-18 |
NN |
denotes |
brain |
T6738 |
7-12 |
JJ |
denotes |
adult |
T6739 |
19-21 |
PRP |
denotes |
we |
T6740 |
22-31 |
RB |
denotes |
generally |
T6741 |
41-42 |
DT |
denotes |
a |
T6742 |
51-63 |
NN |
denotes |
localization |
T6743 |
43-50 |
JJ |
denotes |
nuclear |
T6744 |
64-67 |
IN |
denotes |
for |
T6745 |
68-75 |
NN |
denotes |
Annexin |
T6746 |
76-78 |
NN |
denotes |
A7 |
T6747 |
79-81 |
IN |
denotes |
in |
T6748 |
82-89 |
NNS |
denotes |
neurons |
T6749 |
90-97 |
IN |
denotes |
whereas |
T6750 |
109-118 |
VBD |
denotes |
exhibited |
T6751 |
98-108 |
NNS |
denotes |
astrocytes |
T6752 |
119-123 |
CC |
denotes |
both |
T6753 |
126-135 |
JJ |
denotes |
cytosolic |
T6754 |
124-125 |
DT |
denotes |
a |
T6755 |
136-138 |
RB |
denotes |
as |
T6756 |
144-146 |
IN |
denotes |
as |
T6757 |
139-143 |
RB |
denotes |
well |
T6758 |
147-148 |
DT |
denotes |
a |
T6759 |
149-156 |
JJ |
denotes |
nuclear |
T6760 |
157-165 |
NN |
denotes |
staining |
T6761 |
165-166 |
. |
denotes |
. |
T6762 |
166-341 |
sentence |
denotes |
However, pyramidal neurons of the isocortex and Purkinje-cells of the cerebellum exhibited a cytosolic stain of intermediate intensity including their neurites and dendrites. |
T6763 |
167-174 |
RB |
denotes |
However |
T6764 |
248-257 |
VBD |
denotes |
exhibited |
T6765 |
174-176 |
, |
denotes |
, |
T6766 |
176-185 |
JJ |
denotes |
pyramidal |
T6767 |
186-193 |
NNS |
denotes |
neurons |
T6768 |
194-196 |
IN |
denotes |
of |
T6769 |
197-200 |
DT |
denotes |
the |
T6770 |
201-210 |
NN |
denotes |
isocortex |
T6771 |
211-214 |
CC |
denotes |
and |
T6772 |
215-223 |
NNP |
denotes |
Purkinje |
T6773 |
224-229 |
NNS |
denotes |
cells |
T6774 |
223-224 |
HYPH |
denotes |
- |
T6775 |
230-232 |
IN |
denotes |
of |
T6776 |
233-236 |
DT |
denotes |
the |
T6777 |
237-247 |
NN |
denotes |
cerebellum |
T6778 |
258-259 |
DT |
denotes |
a |
T6779 |
270-275 |
NN |
denotes |
stain |
T6780 |
260-269 |
JJ |
denotes |
cytosolic |
T6781 |
276-278 |
IN |
denotes |
of |
T6782 |
279-291 |
JJ |
denotes |
intermediate |
T6783 |
292-301 |
NN |
denotes |
intensity |
T6784 |
302-311 |
VBG |
denotes |
including |
T6785 |
312-317 |
PRP$ |
denotes |
their |
T6786 |
318-326 |
NNS |
denotes |
neurites |
T6787 |
327-330 |
CC |
denotes |
and |
T6788 |
331-340 |
NNS |
denotes |
dendrites |
T6789 |
340-341 |
. |
denotes |
. |
T6790 |
341-633 |
sentence |
denotes |
We have previously reported the expression of Annexin A7 in human temporal neocortex and hippocampus obtained from neurosurgery for therapy-refractory epilepsy and found the two Annexin A7 isoforms restricted to the cytoplasm and nuclei of astrocytes, whereas neurons lacked any signal [19]. |
T6791 |
342-344 |
PRP |
denotes |
We |
T6792 |
361-369 |
VBN |
denotes |
reported |
T6793 |
345-349 |
VBP |
denotes |
have |
T6794 |
350-360 |
RB |
denotes |
previously |
T6795 |
370-373 |
DT |
denotes |
the |
T6796 |
374-384 |
NN |
denotes |
expression |
T6797 |
385-387 |
IN |
denotes |
of |
T6798 |
388-395 |
NN |
denotes |
Annexin |
T6799 |
396-398 |
NN |
denotes |
A7 |
T6800 |
399-401 |
IN |
denotes |
in |
T6801 |
402-407 |
JJ |
denotes |
human |
T6802 |
417-426 |
NN |
denotes |
neocortex |
T6803 |
408-416 |
JJ |
denotes |
temporal |
T6804 |
427-430 |
CC |
denotes |
and |
T6805 |
431-442 |
NN |
denotes |
hippocampus |
T6806 |
443-451 |
VBN |
denotes |
obtained |
T6807 |
452-456 |
IN |
denotes |
from |
T6808 |
457-469 |
NN |
denotes |
neurosurgery |
T6809 |
470-473 |
IN |
denotes |
for |
T6810 |
474-481 |
NN |
denotes |
therapy |
T6811 |
482-492 |
JJ |
denotes |
refractory |
T6812 |
481-482 |
HYPH |
denotes |
- |
T6813 |
493-501 |
NN |
denotes |
epilepsy |
T6814 |
502-505 |
CC |
denotes |
and |
T6815 |
506-511 |
VBD |
denotes |
found |
T6816 |
512-515 |
DT |
denotes |
the |
T6817 |
531-539 |
NNS |
denotes |
isoforms |
T6818 |
516-519 |
CD |
denotes |
two |
T6819 |
520-527 |
NN |
denotes |
Annexin |
T6820 |
528-530 |
NN |
denotes |
A7 |
T6821 |
540-550 |
VBN |
denotes |
restricted |
T6822 |
551-553 |
IN |
denotes |
to |
T6823 |
554-557 |
DT |
denotes |
the |
T6824 |
558-567 |
NN |
denotes |
cytoplasm |
T6825 |
568-571 |
CC |
denotes |
and |
T6826 |
572-578 |
NNS |
denotes |
nuclei |
T6827 |
579-581 |
IN |
denotes |
of |
T6828 |
582-592 |
NNS |
denotes |
astrocytes |
T6829 |
592-594 |
, |
denotes |
, |
T6830 |
594-601 |
IN |
denotes |
whereas |
T6831 |
610-616 |
VBD |
denotes |
lacked |
T6832 |
602-609 |
NNS |
denotes |
neurons |
T6833 |
617-620 |
DT |
denotes |
any |
T6834 |
621-627 |
NN |
denotes |
signal |
T6835 |
628-629 |
-LRB- |
denotes |
[ |
T6836 |
629-631 |
CD |
denotes |
19 |
T6837 |
631-632 |
-RRB- |
denotes |
] |
T6838 |
632-633 |
. |
denotes |
. |
T6839 |
633-793 |
sentence |
denotes |
The hippocampal area showed typical signs of Ammon's horn sclerosis, but the adjacent temporal neocortex tissue did not show any histopathological alterations. |
T6840 |
634-637 |
DT |
denotes |
The |
T6841 |
650-654 |
NN |
denotes |
area |
T6842 |
638-649 |
JJ |
denotes |
hippocampal |
T6843 |
655-661 |
VBD |
denotes |
showed |
T6844 |
662-669 |
JJ |
denotes |
typical |
T6845 |
670-675 |
NNS |
denotes |
signs |
T6846 |
676-678 |
IN |
denotes |
of |
T6847 |
679-684 |
NNP |
denotes |
Ammon |
T6848 |
692-701 |
NN |
denotes |
sclerosis |
T6849 |
684-686 |
POS |
denotes |
's |
T6850 |
687-691 |
NN |
denotes |
horn |
T6851 |
701-703 |
, |
denotes |
, |
T6852 |
703-706 |
CC |
denotes |
but |
T6853 |
707-710 |
DT |
denotes |
the |
T6854 |
739-745 |
NN |
denotes |
tissue |
T6855 |
711-719 |
JJ |
denotes |
adjacent |
T6856 |
720-728 |
JJ |
denotes |
temporal |
T6857 |
729-738 |
NN |
denotes |
neocortex |
T6858 |
754-758 |
VB |
denotes |
show |
T6859 |
746-749 |
VBD |
denotes |
did |
T6860 |
750-753 |
RB |
denotes |
not |
T6861 |
759-762 |
DT |
denotes |
any |
T6862 |
781-792 |
NNS |
denotes |
alterations |
T6863 |
763-780 |
JJ |
denotes |
histopathological |
T6864 |
792-793 |
. |
denotes |
. |
T6865 |
793-870 |
sentence |
denotes |
This data is in discrepancy with our actual observation in the murine brain. |
T6866 |
794-798 |
DT |
denotes |
This |
T6867 |
799-803 |
NNS |
denotes |
data |
T6868 |
804-806 |
VBZ |
denotes |
is |
T6869 |
807-809 |
IN |
denotes |
in |
T6870 |
810-821 |
NN |
denotes |
discrepancy |
T6871 |
822-826 |
IN |
denotes |
with |
T6872 |
827-830 |
PRP$ |
denotes |
our |
T6873 |
838-849 |
NN |
denotes |
observation |
T6874 |
831-837 |
JJ |
denotes |
actual |
T6875 |
850-852 |
IN |
denotes |
in |
T6876 |
853-856 |
DT |
denotes |
the |
T6877 |
864-869 |
NN |
denotes |
brain |
T6878 |
857-863 |
JJ |
denotes |
murine |
T6879 |
869-870 |
. |
denotes |
. |
T6880 |
870-1061 |
sentence |
denotes |
To determine if this is due to different methods in immunofluorescence staining or indeed different expression patterns in mouse and human, we repeated the immunofluorescence of human brain. |
T6881 |
871-873 |
TO |
denotes |
To |
T6882 |
874-883 |
VB |
denotes |
determine |
T6883 |
1014-1022 |
VBD |
denotes |
repeated |
T6884 |
884-886 |
IN |
denotes |
if |
T6885 |
892-894 |
VBZ |
denotes |
is |
T6886 |
887-891 |
DT |
denotes |
this |
T6887 |
895-898 |
IN |
denotes |
due |
T6888 |
899-901 |
IN |
denotes |
to |
T6889 |
902-911 |
JJ |
denotes |
different |
T6890 |
912-919 |
NNS |
denotes |
methods |
T6891 |
920-922 |
IN |
denotes |
in |
T6892 |
923-941 |
NN |
denotes |
immunofluorescence |
T6893 |
942-950 |
NN |
denotes |
staining |
T6894 |
951-953 |
CC |
denotes |
or |
T6895 |
954-960 |
RB |
denotes |
indeed |
T6896 |
982-990 |
NNS |
denotes |
patterns |
T6897 |
961-970 |
JJ |
denotes |
different |
T6898 |
971-981 |
NN |
denotes |
expression |
T6899 |
991-993 |
IN |
denotes |
in |
T6900 |
994-999 |
NN |
denotes |
mouse |
T6901 |
1000-1003 |
CC |
denotes |
and |
T6902 |
1004-1009 |
JJ |
denotes |
human |
T6903 |
1009-1011 |
, |
denotes |
, |
T6904 |
1011-1013 |
PRP |
denotes |
we |
T6905 |
1023-1026 |
DT |
denotes |
the |
T6906 |
1027-1045 |
NN |
denotes |
immunofluorescence |
T6907 |
1046-1048 |
IN |
denotes |
of |
T6908 |
1049-1054 |
JJ |
denotes |
human |
T6909 |
1055-1060 |
NN |
denotes |
brain |
T6910 |
1060-1061 |
. |
denotes |
. |
T6911 |
1061-1141 |
sentence |
denotes |
This time we investigated sections from human parietal cortex of autopsy brain. |
T6912 |
1062-1066 |
DT |
denotes |
This |
T6913 |
1067-1071 |
NN |
denotes |
time |
T6914 |
1075-1087 |
VBD |
denotes |
investigated |
T6915 |
1072-1074 |
PRP |
denotes |
we |
T6916 |
1088-1096 |
NNS |
denotes |
sections |
T6917 |
1097-1101 |
IN |
denotes |
from |
T6918 |
1102-1107 |
JJ |
denotes |
human |
T6919 |
1117-1123 |
NN |
denotes |
cortex |
T6920 |
1108-1116 |
JJ |
denotes |
parietal |
T6921 |
1124-1126 |
IN |
denotes |
of |
T6922 |
1127-1134 |
NN |
denotes |
autopsy |
T6923 |
1135-1140 |
NN |
denotes |
brain |
T6924 |
1140-1141 |
. |
denotes |
. |
T6925 |
1141-1261 |
sentence |
denotes |
The astroglial expression of Annexin A7 could be confirmed, although not all astrocytes exhibited the nuclear staining. |
T6926 |
1142-1145 |
DT |
denotes |
The |
T6927 |
1157-1167 |
NN |
denotes |
expression |
T6928 |
1146-1156 |
JJ |
denotes |
astroglial |
T6929 |
1191-1200 |
VBN |
denotes |
confirmed |
T6930 |
1168-1170 |
IN |
denotes |
of |
T6931 |
1171-1178 |
NN |
denotes |
Annexin |
T6932 |
1179-1181 |
NN |
denotes |
A7 |
T6933 |
1182-1187 |
MD |
denotes |
could |
T6934 |
1188-1190 |
VB |
denotes |
be |
T6935 |
1200-1202 |
, |
denotes |
, |
T6936 |
1202-1210 |
IN |
denotes |
although |
T6937 |
1230-1239 |
VBD |
denotes |
exhibited |
T6938 |
1211-1214 |
RB |
denotes |
not |
T6939 |
1219-1229 |
NNS |
denotes |
astrocytes |
T6940 |
1215-1218 |
DT |
denotes |
all |
T6941 |
1240-1243 |
DT |
denotes |
the |
T6942 |
1252-1260 |
NN |
denotes |
staining |
T6943 |
1244-1251 |
JJ |
denotes |
nuclear |
T6944 |
1260-1261 |
. |
denotes |
. |
T6945 |
1261-1369 |
sentence |
denotes |
Pyramidal neurons however indicated a distinct staining of Annexin A7 most prominent along their dendrites. |
T6946 |
1262-1271 |
JJ |
denotes |
Pyramidal |
T6947 |
1272-1279 |
NNS |
denotes |
neurons |
T6948 |
1288-1297 |
VBD |
denotes |
indicated |
T6949 |
1280-1287 |
RB |
denotes |
however |
T6950 |
1298-1299 |
DT |
denotes |
a |
T6951 |
1309-1317 |
NN |
denotes |
staining |
T6952 |
1300-1308 |
JJ |
denotes |
distinct |
T6953 |
1318-1320 |
IN |
denotes |
of |
T6954 |
1321-1328 |
NN |
denotes |
Annexin |
T6955 |
1329-1331 |
NN |
denotes |
A7 |
T6956 |
1332-1336 |
RBS |
denotes |
most |
T6957 |
1337-1346 |
JJ |
denotes |
prominent |
T6958 |
1347-1352 |
IN |
denotes |
along |
T6959 |
1353-1358 |
PRP$ |
denotes |
their |
T6960 |
1359-1368 |
NNS |
denotes |
dendrites |
T6961 |
1368-1369 |
. |
denotes |
. |
T6962 |
1369-1572 |
sentence |
denotes |
The different results obtained for the neurons may be explained by the fact that we previously used frozen tissue sections or that they were derived from patients suffering from temporal lobe epilepsia. |
T6963 |
1370-1373 |
DT |
denotes |
The |
T6964 |
1384-1391 |
NNS |
denotes |
results |
T6965 |
1374-1383 |
JJ |
denotes |
different |
T6966 |
1424-1433 |
VBN |
denotes |
explained |
T6967 |
1392-1400 |
VBN |
denotes |
obtained |
T6968 |
1401-1404 |
IN |
denotes |
for |
T6969 |
1405-1408 |
DT |
denotes |
the |
T6970 |
1409-1416 |
NNS |
denotes |
neurons |
T6971 |
1417-1420 |
MD |
denotes |
may |
T6972 |
1421-1423 |
VB |
denotes |
be |
T6973 |
1434-1436 |
IN |
denotes |
by |
T6974 |
1437-1440 |
DT |
denotes |
the |
T6975 |
1441-1445 |
NN |
denotes |
fact |
T6976 |
1446-1450 |
IN |
denotes |
that |
T6977 |
1465-1469 |
VBD |
denotes |
used |
T6978 |
1451-1453 |
PRP |
denotes |
we |
T6979 |
1454-1464 |
RB |
denotes |
previously |
T6980 |
1470-1476 |
JJ |
denotes |
frozen |
T6981 |
1484-1492 |
NNS |
denotes |
sections |
T6982 |
1477-1483 |
NN |
denotes |
tissue |
T6983 |
1493-1495 |
CC |
denotes |
or |
T6984 |
1496-1500 |
IN |
denotes |
that |
T6985 |
1511-1518 |
VBN |
denotes |
derived |
T6986 |
1501-1505 |
PRP |
denotes |
they |
T6987 |
1506-1510 |
VBD |
denotes |
were |
T6988 |
1519-1523 |
IN |
denotes |
from |
T6989 |
1524-1532 |
NNS |
denotes |
patients |
T6990 |
1533-1542 |
VBG |
denotes |
suffering |
T6991 |
1543-1547 |
IN |
denotes |
from |
T6992 |
1548-1556 |
JJ |
denotes |
temporal |
T6993 |
1557-1561 |
NN |
denotes |
lobe |
T6994 |
1562-1571 |
NN |
denotes |
epilepsia |
T6995 |
1571-1572 |
. |
denotes |
. |
T6996 |
1572-1718 |
sentence |
denotes |
On the other hand the actual human brain tissue used was from aged patients and did not correspond to the age of the mice included in this study. |
T6997 |
1573-1575 |
IN |
denotes |
On |
T6998 |
1626-1629 |
VBD |
denotes |
was |
T6999 |
1576-1579 |
DT |
denotes |
the |
T7000 |
1586-1590 |
NN |
denotes |
hand |
T7001 |
1580-1585 |
JJ |
denotes |
other |
T7002 |
1591-1594 |
DT |
denotes |
the |
T7003 |
1614-1620 |
NN |
denotes |
tissue |
T7004 |
1595-1601 |
JJ |
denotes |
actual |
T7005 |
1602-1607 |
JJ |
denotes |
human |
T7006 |
1608-1613 |
NN |
denotes |
brain |
T7007 |
1621-1625 |
VBN |
denotes |
used |
T7008 |
1630-1634 |
IN |
denotes |
from |
T7009 |
1635-1639 |
JJ |
denotes |
aged |
T7010 |
1640-1648 |
NNS |
denotes |
patients |
T7011 |
1649-1652 |
CC |
denotes |
and |
T7012 |
1653-1656 |
VBD |
denotes |
did |
T7013 |
1661-1671 |
VB |
denotes |
correspond |
T7014 |
1657-1660 |
RB |
denotes |
not |
T7015 |
1672-1674 |
IN |
denotes |
to |
T7016 |
1675-1678 |
DT |
denotes |
the |
T7017 |
1679-1682 |
NN |
denotes |
age |
T7018 |
1683-1685 |
IN |
denotes |
of |
T7019 |
1686-1689 |
DT |
denotes |
the |
T7020 |
1690-1694 |
NNS |
denotes |
mice |
T7021 |
1695-1703 |
VBN |
denotes |
included |
T7022 |
1704-1706 |
IN |
denotes |
in |
T7023 |
1707-1711 |
DT |
denotes |
this |
T7024 |
1712-1717 |
NN |
denotes |
study |
T7025 |
1717-1718 |
. |
denotes |
. |
T7026 |
1718-1907 |
sentence |
denotes |
In cultured cells after cell damage or apoptosis (unpublished observations) or in cells treated with a Ca2+-ionophore Annexin A7 translocated from the cytoplasm to cellular membranes [19]. |
T7027 |
1719-1721 |
IN |
denotes |
In |
T7028 |
1848-1860 |
VBN |
denotes |
translocated |
T7029 |
1722-1730 |
VBN |
denotes |
cultured |
T7030 |
1731-1736 |
NNS |
denotes |
cells |
T7031 |
1737-1742 |
IN |
denotes |
after |
T7032 |
1743-1747 |
NN |
denotes |
cell |
T7033 |
1748-1754 |
NN |
denotes |
damage |
T7034 |
1755-1757 |
CC |
denotes |
or |
T7035 |
1758-1767 |
NN |
denotes |
apoptosis |
T7036 |
1768-1769 |
-LRB- |
denotes |
( |
T7037 |
1781-1793 |
NNS |
denotes |
observations |
T7038 |
1769-1780 |
JJ |
denotes |
unpublished |
T7039 |
1793-1794 |
-RRB- |
denotes |
) |
T7040 |
1795-1797 |
CC |
denotes |
or |
T7041 |
1798-1800 |
IN |
denotes |
in |
T7042 |
1801-1806 |
NNS |
denotes |
cells |
T7043 |
1807-1814 |
VBN |
denotes |
treated |
T7044 |
1815-1819 |
IN |
denotes |
with |
T7045 |
1820-1821 |
DT |
denotes |
a |
T7046 |
1827-1836 |
NN |
denotes |
ionophore |
T7047 |
1822-1826 |
NN |
denotes |
Ca2+ |
T7048 |
1826-1827 |
HYPH |
denotes |
- |
T7049 |
1837-1844 |
NN |
denotes |
Annexin |
T7050 |
1845-1847 |
NN |
denotes |
A7 |
T7051 |
1861-1865 |
IN |
denotes |
from |
T7052 |
1866-1869 |
DT |
denotes |
the |
T7053 |
1870-1879 |
NN |
denotes |
cytoplasm |
T7054 |
1880-1882 |
IN |
denotes |
to |
T7055 |
1883-1891 |
JJ |
denotes |
cellular |
T7056 |
1892-1901 |
NNS |
denotes |
membranes |
T7057 |
1902-1903 |
-LRB- |
denotes |
[ |
T7058 |
1903-1905 |
CD |
denotes |
19 |
T7059 |
1905-1906 |
-RRB- |
denotes |
] |
T7060 |
1906-1907 |
. |
denotes |
. |
T7061 |
1907-2067 |
sentence |
denotes |
We therefore favor the hypothesis that Annexin A7 in the sensitive neurons of the human autopsy brain may have similarly translocated to the cellular membrane. |
T7062 |
1908-1910 |
PRP |
denotes |
We |
T7063 |
1921-1926 |
VBP |
denotes |
favor |
T7064 |
1911-1920 |
RB |
denotes |
therefore |
T7065 |
1927-1930 |
DT |
denotes |
the |
T7066 |
1931-1941 |
NN |
denotes |
hypothesis |
T7067 |
1942-1946 |
IN |
denotes |
that |
T7068 |
2029-2041 |
VBN |
denotes |
translocated |
T7069 |
1947-1954 |
NN |
denotes |
Annexin |
T7070 |
1955-1957 |
NN |
denotes |
A7 |
T7071 |
1958-1960 |
IN |
denotes |
in |
T7072 |
1961-1964 |
DT |
denotes |
the |
T7073 |
1975-1982 |
NNS |
denotes |
neurons |
T7074 |
1965-1974 |
JJ |
denotes |
sensitive |
T7075 |
1983-1985 |
IN |
denotes |
of |
T7076 |
1986-1989 |
DT |
denotes |
the |
T7077 |
2004-2009 |
NN |
denotes |
brain |
T7078 |
1990-1995 |
JJ |
denotes |
human |
T7079 |
1996-2003 |
NN |
denotes |
autopsy |
T7080 |
2010-2013 |
MD |
denotes |
may |
T7081 |
2014-2018 |
VB |
denotes |
have |
T7082 |
2019-2028 |
RB |
denotes |
similarly |
T7083 |
2042-2044 |
IN |
denotes |
to |
T7084 |
2045-2048 |
DT |
denotes |
the |
T7085 |
2058-2066 |
NN |
denotes |
membrane |
T7086 |
2049-2057 |
JJ |
denotes |
cellular |
T7087 |
2066-2067 |
. |
denotes |
. |
T7088 |
2067-2231 |
sentence |
denotes |
This property of translocation and membrane binding is common to all annexins and commercially available kits for apoptosis detection employ recombinant AnnexinA5. |
T7089 |
2068-2072 |
DT |
denotes |
This |
T7090 |
2073-2081 |
NN |
denotes |
property |
T7091 |
2120-2122 |
VBZ |
denotes |
is |
T7092 |
2082-2084 |
IN |
denotes |
of |
T7093 |
2085-2098 |
NN |
denotes |
translocation |
T7094 |
2099-2102 |
CC |
denotes |
and |
T7095 |
2103-2111 |
NN |
denotes |
membrane |
T7096 |
2112-2119 |
NN |
denotes |
binding |
T7097 |
2123-2129 |
JJ |
denotes |
common |
T7098 |
2130-2132 |
IN |
denotes |
to |
T7099 |
2133-2136 |
DT |
denotes |
all |
T7100 |
2137-2145 |
NNS |
denotes |
annexins |
T7101 |
2146-2149 |
CC |
denotes |
and |
T7102 |
2150-2162 |
RB |
denotes |
commercially |
T7103 |
2163-2172 |
JJ |
denotes |
available |
T7104 |
2173-2177 |
NNS |
denotes |
kits |
T7105 |
2202-2208 |
VBP |
denotes |
employ |
T7106 |
2178-2181 |
IN |
denotes |
for |
T7107 |
2182-2191 |
NN |
denotes |
apoptosis |
T7108 |
2192-2201 |
NN |
denotes |
detection |
T7109 |
2209-2220 |
JJ |
denotes |
recombinant |
T7110 |
2221-2230 |
NN |
denotes |
AnnexinA5 |
T7111 |
2230-2231 |
. |
denotes |
. |
T7112 |
2231-2412 |
sentence |
denotes |
The presence of nuclear Annexin A7 in murine brain was confirmed by controls using sections from the AnxA7-/- mouse and by a biochemical extraction of the protein from the nucleus. |
T7113 |
2232-2235 |
DT |
denotes |
The |
T7114 |
2236-2244 |
NN |
denotes |
presence |
T7115 |
2287-2296 |
VBN |
denotes |
confirmed |
T7116 |
2245-2247 |
IN |
denotes |
of |
T7117 |
2248-2255 |
JJ |
denotes |
nuclear |
T7118 |
2264-2266 |
NN |
denotes |
A7 |
T7119 |
2256-2263 |
NN |
denotes |
Annexin |
T7120 |
2267-2269 |
IN |
denotes |
in |
T7121 |
2270-2276 |
JJ |
denotes |
murine |
T7122 |
2277-2282 |
NN |
denotes |
brain |
T7123 |
2283-2286 |
VBD |
denotes |
was |
T7124 |
2297-2299 |
IN |
denotes |
by |
T7125 |
2300-2308 |
NNS |
denotes |
controls |
T7126 |
2309-2314 |
VBG |
denotes |
using |
T7127 |
2315-2323 |
NNS |
denotes |
sections |
T7128 |
2324-2328 |
IN |
denotes |
from |
T7129 |
2329-2332 |
DT |
denotes |
the |
T7130 |
2342-2347 |
NN |
denotes |
mouse |
T7131 |
2333-2338 |
NN |
denotes |
AnxA7 |
T7132 |
2338-2339 |
SYM |
denotes |
- |
T7133 |
2339-2340 |
HYPH |
denotes |
/ |
T7134 |
2340-2341 |
SYM |
denotes |
- |
T7135 |
2348-2351 |
CC |
denotes |
and |
T7136 |
2352-2354 |
IN |
denotes |
by |
T7137 |
2355-2356 |
DT |
denotes |
a |
T7138 |
2369-2379 |
NN |
denotes |
extraction |
T7139 |
2357-2368 |
JJ |
denotes |
biochemical |
T7140 |
2380-2382 |
IN |
denotes |
of |
T7141 |
2383-2386 |
DT |
denotes |
the |
T7142 |
2387-2394 |
NN |
denotes |
protein |
T7143 |
2395-2399 |
IN |
denotes |
from |
T7144 |
2400-2403 |
DT |
denotes |
the |
T7145 |
2404-2411 |
NN |
denotes |
nucleus |
T7146 |
2411-2412 |
. |
denotes |
. |
T7147 |
2412-2598 |
sentence |
denotes |
Both Annexin A7 isoforms described in brain tissue seemingly are expressed by neurons and astrocytes, which was shown using total cell extracts of cultured neuo-2a, PC-12, and C6 cells. |
T7148 |
2413-2417 |
DT |
denotes |
Both |
T7149 |
2429-2437 |
NNS |
denotes |
isoforms |
T7150 |
2418-2425 |
NN |
denotes |
Annexin |
T7151 |
2426-2428 |
NN |
denotes |
A7 |
T7152 |
2478-2487 |
VBN |
denotes |
expressed |
T7153 |
2438-2447 |
VBN |
denotes |
described |
T7154 |
2448-2450 |
IN |
denotes |
in |
T7155 |
2451-2456 |
NN |
denotes |
brain |
T7156 |
2457-2463 |
NN |
denotes |
tissue |
T7157 |
2464-2473 |
RB |
denotes |
seemingly |
T7158 |
2474-2477 |
VBP |
denotes |
are |
T7159 |
2488-2490 |
IN |
denotes |
by |
T7160 |
2491-2498 |
NNS |
denotes |
neurons |
T7161 |
2499-2502 |
CC |
denotes |
and |
T7162 |
2503-2513 |
NNS |
denotes |
astrocytes |
T7163 |
2513-2515 |
, |
denotes |
, |
T7164 |
2515-2520 |
WDT |
denotes |
which |
T7165 |
2525-2530 |
VBN |
denotes |
shown |
T7166 |
2521-2524 |
VBD |
denotes |
was |
T7167 |
2531-2536 |
VBG |
denotes |
using |
T7168 |
2537-2542 |
JJ |
denotes |
total |
T7169 |
2548-2556 |
NNS |
denotes |
extracts |
T7170 |
2543-2547 |
NN |
denotes |
cell |
T7171 |
2557-2559 |
IN |
denotes |
of |
T7172 |
2560-2568 |
VBN |
denotes |
cultured |
T7173 |
2592-2597 |
NNS |
denotes |
cells |
T7174 |
2569-2573 |
NN |
denotes |
neuo |
T7175 |
2573-2574 |
HYPH |
denotes |
- |
T7176 |
2574-2576 |
CD |
denotes |
2a |
T7177 |
2576-2578 |
, |
denotes |
, |
T7178 |
2578-2580 |
NN |
denotes |
PC |
T7179 |
2580-2581 |
HYPH |
denotes |
- |
T7180 |
2581-2583 |
CD |
denotes |
12 |
T7181 |
2583-2585 |
, |
denotes |
, |
T7182 |
2585-2588 |
CC |
denotes |
and |
T7183 |
2589-2591 |
NN |
denotes |
C6 |
T7184 |
2597-2598 |
. |
denotes |
. |
T7185 |
2598-2733 |
sentence |
denotes |
In addition to their expression in brain, both Annexin A7 isoforms have only been described in heart muscle and red blood cells [5-8]. |
T7186 |
2599-2601 |
IN |
denotes |
In |
T7187 |
2681-2690 |
VBN |
denotes |
described |
T7188 |
2602-2610 |
NN |
denotes |
addition |
T7189 |
2611-2613 |
IN |
denotes |
to |
T7190 |
2614-2619 |
PRP$ |
denotes |
their |
T7191 |
2620-2630 |
NN |
denotes |
expression |
T7192 |
2631-2633 |
IN |
denotes |
in |
T7193 |
2634-2639 |
NN |
denotes |
brain |
T7194 |
2639-2641 |
, |
denotes |
, |
T7195 |
2641-2645 |
CC |
denotes |
both |
T7196 |
2657-2665 |
NNS |
denotes |
isoforms |
T7197 |
2646-2653 |
NN |
denotes |
Annexin |
T7198 |
2654-2656 |
NN |
denotes |
A7 |
T7199 |
2666-2670 |
VBP |
denotes |
have |
T7200 |
2671-2675 |
RB |
denotes |
only |
T7201 |
2676-2680 |
VBN |
denotes |
been |
T7202 |
2691-2693 |
IN |
denotes |
in |
T7203 |
2694-2699 |
NN |
denotes |
heart |
T7204 |
2700-2706 |
NN |
denotes |
muscle |
T7205 |
2707-2710 |
CC |
denotes |
and |
T7206 |
2711-2714 |
JJ |
denotes |
red |
T7207 |
2721-2726 |
NNS |
denotes |
cells |
T7208 |
2715-2720 |
NN |
denotes |
blood |
T7209 |
2727-2728 |
-LRB- |
denotes |
[ |
T7210 |
2728-2729 |
CD |
denotes |
5 |
T7211 |
2729-2730 |
SYM |
denotes |
- |
T7212 |
2730-2731 |
CD |
denotes |
8 |
T7213 |
2731-2732 |
-RRB- |
denotes |
] |
T7214 |
2732-2733 |
. |
denotes |
. |
R2892 |
T6734 |
T6735 |
prep |
In,observed |
R2893 |
T6736 |
T6737 |
det |
the,brain |
R2894 |
T6737 |
T6734 |
pobj |
brain,In |
R2895 |
T6738 |
T6737 |
amod |
adult,brain |
R2896 |
T6739 |
T6735 |
nsubj |
we,observed |
R2897 |
T6740 |
T6735 |
advmod |
generally,observed |
R2898 |
T6741 |
T6742 |
det |
a,localization |
R2899 |
T6742 |
T6735 |
dobj |
localization,observed |
R2900 |
T6743 |
T6742 |
amod |
nuclear,localization |
R2901 |
T6744 |
T6735 |
prep |
for,observed |
R2902 |
T6745 |
T6746 |
compound |
Annexin,A7 |
R2903 |
T6746 |
T6744 |
pobj |
A7,for |
R2904 |
T6747 |
T6735 |
prep |
in,observed |
R2905 |
T6748 |
T6747 |
pobj |
neurons,in |
R2906 |
T6749 |
T6750 |
mark |
whereas,exhibited |
R2907 |
T6750 |
T6735 |
advcl |
exhibited,observed |
R2908 |
T6751 |
T6750 |
nsubj |
astrocytes,exhibited |
R2909 |
T6752 |
T6753 |
preconj |
both,cytosolic |
R2910 |
T6753 |
T6750 |
dobj |
cytosolic,exhibited |
R2911 |
T6754 |
T6753 |
det |
a,cytosolic |
R2912 |
T6755 |
T6756 |
advmod |
as,as |
R2913 |
T6756 |
T6753 |
cc |
as,cytosolic |
R2914 |
T6757 |
T6756 |
advmod |
well,as |
R2915 |
T6758 |
T6759 |
det |
a,nuclear |
R2916 |
T6759 |
T6760 |
nmod |
nuclear,staining |
R2917 |
T6760 |
T6753 |
conj |
staining,cytosolic |
R2918 |
T6761 |
T6735 |
punct |
.,observed |
R2919 |
T6763 |
T6764 |
advmod |
However,exhibited |
R2920 |
T6765 |
T6764 |
punct |
", ",exhibited |
R2921 |
T6766 |
T6767 |
amod |
pyramidal,neurons |
R2922 |
T6767 |
T6764 |
nsubj |
neurons,exhibited |
R2923 |
T6768 |
T6767 |
prep |
of,neurons |
R2924 |
T6769 |
T6770 |
det |
the,isocortex |
R2925 |
T6770 |
T6768 |
pobj |
isocortex,of |
R2926 |
T6771 |
T6767 |
cc |
and,neurons |
R2927 |
T6772 |
T6773 |
compound |
Purkinje,cells |
R2928 |
T6773 |
T6767 |
conj |
cells,neurons |
R2929 |
T6774 |
T6773 |
punct |
-,cells |
R2930 |
T6775 |
T6773 |
prep |
of,cells |
R2931 |
T6776 |
T6777 |
det |
the,cerebellum |
R2932 |
T6777 |
T6775 |
pobj |
cerebellum,of |
R2933 |
T6778 |
T6779 |
det |
a,stain |
R2934 |
T6779 |
T6764 |
dobj |
stain,exhibited |
R2935 |
T6780 |
T6779 |
amod |
cytosolic,stain |
R2936 |
T6781 |
T6779 |
prep |
of,stain |
R2937 |
T6782 |
T6783 |
amod |
intermediate,intensity |
R2938 |
T6783 |
T6781 |
pobj |
intensity,of |
R2939 |
T6784 |
T6764 |
prep |
including,exhibited |
R2940 |
T6785 |
T6786 |
poss |
their,neurites |
R2941 |
T6786 |
T6784 |
pobj |
neurites,including |
R2942 |
T6787 |
T6786 |
cc |
and,neurites |
R2943 |
T6788 |
T6786 |
conj |
dendrites,neurites |
R2944 |
T6789 |
T6764 |
punct |
.,exhibited |
R2945 |
T6791 |
T6792 |
nsubj |
We,reported |
R2946 |
T6793 |
T6792 |
aux |
have,reported |
R2947 |
T6794 |
T6792 |
advmod |
previously,reported |
R2948 |
T6795 |
T6796 |
det |
the,expression |
R2949 |
T6796 |
T6792 |
dobj |
expression,reported |
R2950 |
T6797 |
T6796 |
prep |
of,expression |
R2951 |
T6798 |
T6799 |
compound |
Annexin,A7 |
R2952 |
T6799 |
T6797 |
pobj |
A7,of |
R2953 |
T6800 |
T6796 |
prep |
in,expression |
R2954 |
T6801 |
T6802 |
amod |
human,neocortex |
R2955 |
T6802 |
T6800 |
pobj |
neocortex,in |
R2956 |
T6803 |
T6802 |
amod |
temporal,neocortex |
R2957 |
T6804 |
T6802 |
cc |
and,neocortex |
R2958 |
T6805 |
T6802 |
conj |
hippocampus,neocortex |
R2959 |
T6806 |
T6802 |
acl |
obtained,neocortex |
R2960 |
T6807 |
T6806 |
prep |
from,obtained |
R2961 |
T6808 |
T6807 |
pobj |
neurosurgery,from |
R2962 |
T6809 |
T6808 |
prep |
for,neurosurgery |
R2963 |
T6810 |
T6811 |
npadvmod |
therapy,refractory |
R2964 |
T6811 |
T6813 |
amod |
refractory,epilepsy |
R2965 |
T6812 |
T6811 |
punct |
-,refractory |
R2966 |
T6813 |
T6809 |
pobj |
epilepsy,for |
R2967 |
T6814 |
T6792 |
cc |
and,reported |
R2968 |
T6815 |
T6792 |
conj |
found,reported |
R2969 |
T6816 |
T6817 |
det |
the,isoforms |
R2970 |
T6817 |
T6815 |
dobj |
isoforms,found |
R2971 |
T6818 |
T6817 |
nummod |
two,isoforms |
R2972 |
T6819 |
T6820 |
compound |
Annexin,A7 |
R2973 |
T6820 |
T6817 |
compound |
A7,isoforms |
R2974 |
T6821 |
T6817 |
acl |
restricted,isoforms |
R2975 |
T6822 |
T6821 |
prep |
to,restricted |
R2976 |
T6823 |
T6824 |
det |
the,cytoplasm |
R2977 |
T6824 |
T6822 |
pobj |
cytoplasm,to |
R2978 |
T6825 |
T6824 |
cc |
and,cytoplasm |
R2979 |
T6826 |
T6824 |
conj |
nuclei,cytoplasm |
R2980 |
T6827 |
T6824 |
prep |
of,cytoplasm |
R2981 |
T6828 |
T6827 |
pobj |
astrocytes,of |
R2982 |
T6829 |
T6815 |
punct |
", ",found |
R2983 |
T6830 |
T6831 |
mark |
whereas,lacked |
R2984 |
T6831 |
T6815 |
advcl |
lacked,found |
R2985 |
T6832 |
T6831 |
nsubj |
neurons,lacked |
R2986 |
T6833 |
T6834 |
det |
any,signal |
R2987 |
T6834 |
T6831 |
dobj |
signal,lacked |
R2988 |
T6835 |
T6836 |
punct |
[,19 |
R2989 |
T6836 |
T6815 |
parataxis |
19,found |
R2990 |
T6837 |
T6836 |
punct |
],19 |
R2991 |
T6838 |
T6792 |
punct |
.,reported |
R2992 |
T6840 |
T6841 |
det |
The,area |
R2993 |
T6841 |
T6843 |
nsubj |
area,showed |
R2994 |
T6842 |
T6841 |
amod |
hippocampal,area |
R2995 |
T6844 |
T6845 |
amod |
typical,signs |
R2996 |
T6845 |
T6843 |
dobj |
signs,showed |
R2997 |
T6846 |
T6845 |
prep |
of,signs |
R2998 |
T6847 |
T6848 |
poss |
Ammon,sclerosis |
R2999 |
T6848 |
T6846 |
pobj |
sclerosis,of |
R3000 |
T6849 |
T6847 |
case |
's,Ammon |
R3001 |
T6850 |
T6848 |
compound |
horn,sclerosis |
R3002 |
T6851 |
T6843 |
punct |
", ",showed |
R3003 |
T6852 |
T6843 |
cc |
but,showed |
R3004 |
T6853 |
T6854 |
det |
the,tissue |
R3005 |
T6854 |
T6858 |
nsubj |
tissue,show |
R3006 |
T6855 |
T6854 |
amod |
adjacent,tissue |
R3007 |
T6856 |
T6857 |
amod |
temporal,neocortex |
R3008 |
T6857 |
T6854 |
compound |
neocortex,tissue |
R3009 |
T6858 |
T6843 |
conj |
show,showed |
R3010 |
T6859 |
T6858 |
aux |
did,show |
R3011 |
T6860 |
T6858 |
neg |
not,show |
R3012 |
T6861 |
T6862 |
det |
any,alterations |
R3013 |
T6862 |
T6858 |
dobj |
alterations,show |
R3014 |
T6863 |
T6862 |
amod |
histopathological,alterations |
R3015 |
T6864 |
T6858 |
punct |
.,show |
R3016 |
T6866 |
T6867 |
det |
This,data |
R3017 |
T6867 |
T6868 |
nsubj |
data,is |
R3018 |
T6869 |
T6868 |
prep |
in,is |
R3019 |
T6870 |
T6869 |
pobj |
discrepancy,in |
R3020 |
T6871 |
T6870 |
prep |
with,discrepancy |
R3021 |
T6872 |
T6873 |
poss |
our,observation |
R3022 |
T6873 |
T6871 |
pobj |
observation,with |
R3023 |
T6874 |
T6873 |
amod |
actual,observation |
R3024 |
T6875 |
T6868 |
prep |
in,is |
R3025 |
T6876 |
T6877 |
det |
the,brain |
R3026 |
T6877 |
T6875 |
pobj |
brain,in |
R3027 |
T6878 |
T6877 |
amod |
murine,brain |
R3028 |
T6879 |
T6868 |
punct |
.,is |
R3029 |
T6881 |
T6882 |
aux |
To,determine |
R3030 |
T6882 |
T6883 |
advcl |
determine,repeated |
R3031 |
T6884 |
T6885 |
mark |
if,is |
R3032 |
T6885 |
T6882 |
ccomp |
is,determine |
R3033 |
T6886 |
T6885 |
nsubj |
this,is |
R3034 |
T6887 |
T6885 |
prep |
due,is |
R3035 |
T6888 |
T6887 |
pcomp |
to,due |
R3036 |
T6889 |
T6890 |
amod |
different,methods |
R3037 |
T6890 |
T6887 |
pobj |
methods,due |
R3038 |
T6891 |
T6890 |
prep |
in,methods |
R3039 |
T6892 |
T6893 |
compound |
immunofluorescence,staining |
R3040 |
T6893 |
T6891 |
pobj |
staining,in |
R3041 |
T6894 |
T6890 |
cc |
or,methods |
R3042 |
T6895 |
T6896 |
advmod |
indeed,patterns |
R3043 |
T6896 |
T6890 |
conj |
patterns,methods |
R3044 |
T6897 |
T6896 |
amod |
different,patterns |
R3045 |
T6898 |
T6896 |
compound |
expression,patterns |
R3046 |
T6899 |
T6896 |
prep |
in,patterns |
R3047 |
T6900 |
T6899 |
pobj |
mouse,in |
R3048 |
T6901 |
T6900 |
cc |
and,mouse |
R3049 |
T6902 |
T6900 |
conj |
human,mouse |
R3050 |
T6903 |
T6883 |
punct |
", ",repeated |
R3051 |
T6904 |
T6883 |
nsubj |
we,repeated |
R3052 |
T6905 |
T6906 |
det |
the,immunofluorescence |
R3053 |
T6906 |
T6883 |
dobj |
immunofluorescence,repeated |
R3054 |
T6907 |
T6906 |
prep |
of,immunofluorescence |
R3055 |
T6908 |
T6909 |
amod |
human,brain |
R3056 |
T6909 |
T6907 |
pobj |
brain,of |
R3057 |
T6910 |
T6883 |
punct |
.,repeated |
R3058 |
T6912 |
T6913 |
det |
This,time |
R3059 |
T6913 |
T6914 |
npadvmod |
time,investigated |
R3060 |
T6915 |
T6914 |
nsubj |
we,investigated |
R3061 |
T6916 |
T6914 |
dobj |
sections,investigated |
R3062 |
T6917 |
T6916 |
prep |
from,sections |
R3063 |
T6918 |
T6919 |
amod |
human,cortex |
R3064 |
T6919 |
T6917 |
pobj |
cortex,from |
R3065 |
T6920 |
T6919 |
amod |
parietal,cortex |
R3066 |
T6921 |
T6919 |
prep |
of,cortex |
R3067 |
T6922 |
T6923 |
compound |
autopsy,brain |
R3068 |
T6923 |
T6921 |
pobj |
brain,of |
R3069 |
T6924 |
T6914 |
punct |
.,investigated |
R3070 |
T6926 |
T6927 |
det |
The,expression |
R3071 |
T6927 |
T6929 |
nsubjpass |
expression,confirmed |
R3072 |
T6928 |
T6927 |
amod |
astroglial,expression |
R3073 |
T6930 |
T6927 |
prep |
of,expression |
R3074 |
T6931 |
T6932 |
compound |
Annexin,A7 |
R3075 |
T6932 |
T6930 |
pobj |
A7,of |
R3076 |
T6933 |
T6929 |
aux |
could,confirmed |
R3077 |
T6934 |
T6929 |
auxpass |
be,confirmed |
R3078 |
T6935 |
T6929 |
punct |
", ",confirmed |
R3079 |
T6936 |
T6937 |
mark |
although,exhibited |
R3080 |
T6937 |
T6929 |
advcl |
exhibited,confirmed |
R3081 |
T6938 |
T6939 |
neg |
not,astrocytes |
R3082 |
T6939 |
T6937 |
nsubj |
astrocytes,exhibited |
R3083 |
T6940 |
T6939 |
det |
all,astrocytes |
R3084 |
T6941 |
T6942 |
det |
the,staining |
R3085 |
T6942 |
T6937 |
dobj |
staining,exhibited |
R3086 |
T6943 |
T6942 |
amod |
nuclear,staining |
R3087 |
T6944 |
T6929 |
punct |
.,confirmed |
R3088 |
T6946 |
T6947 |
amod |
Pyramidal,neurons |
R3089 |
T6947 |
T6948 |
nsubj |
neurons,indicated |
R3090 |
T6949 |
T6948 |
advmod |
however,indicated |
R3091 |
T6950 |
T6951 |
det |
a,staining |
R3092 |
T6951 |
T6948 |
dobj |
staining,indicated |
R3093 |
T6952 |
T6951 |
amod |
distinct,staining |
R3094 |
T6953 |
T6951 |
prep |
of,staining |
R3095 |
T6954 |
T6955 |
compound |
Annexin,A7 |
R3096 |
T6955 |
T6953 |
pobj |
A7,of |
R3097 |
T6956 |
T6957 |
advmod |
most,prominent |
R3098 |
T6957 |
T6951 |
relcl |
prominent,staining |
R3099 |
T6958 |
T6957 |
prep |
along,prominent |
R3100 |
T6959 |
T6960 |
poss |
their,dendrites |
R3101 |
T6960 |
T6958 |
pobj |
dendrites,along |
R3102 |
T6961 |
T6948 |
punct |
.,indicated |
R3103 |
T6963 |
T6964 |
det |
The,results |
R3104 |
T6964 |
T6966 |
nsubjpass |
results,explained |
R3105 |
T6965 |
T6964 |
amod |
different,results |
R3106 |
T6967 |
T6964 |
acl |
obtained,results |
R3107 |
T6968 |
T6967 |
prep |
for,obtained |
R3108 |
T6969 |
T6970 |
det |
the,neurons |
R3109 |
T6970 |
T6968 |
pobj |
neurons,for |
R3110 |
T6971 |
T6966 |
aux |
may,explained |
R3111 |
T6972 |
T6966 |
auxpass |
be,explained |
R3112 |
T6973 |
T6966 |
agent |
by,explained |
R3113 |
T6974 |
T6975 |
det |
the,fact |
R3114 |
T6975 |
T6973 |
pobj |
fact,by |
R3115 |
T6976 |
T6977 |
mark |
that,used |
R3116 |
T6977 |
T6975 |
advcl |
used,fact |
R3117 |
T6978 |
T6977 |
nsubj |
we,used |
R3118 |
T6979 |
T6977 |
advmod |
previously,used |
R3119 |
T6980 |
T6981 |
amod |
frozen,sections |
R3120 |
T6981 |
T6977 |
dobj |
sections,used |
R3121 |
T6982 |
T6981 |
compound |
tissue,sections |
R3122 |
T6983 |
T6977 |
cc |
or,used |
R3123 |
T6984 |
T6985 |
mark |
that,derived |
R3124 |
T6985 |
T6977 |
conj |
derived,used |
R3125 |
T6986 |
T6985 |
nsubjpass |
they,derived |
R3126 |
T6987 |
T6985 |
auxpass |
were,derived |
R3127 |
T6988 |
T6985 |
prep |
from,derived |
R3128 |
T6989 |
T6988 |
pobj |
patients,from |
R3129 |
T6990 |
T6989 |
acl |
suffering,patients |
R3130 |
T6991 |
T6990 |
prep |
from,suffering |
R3131 |
T6992 |
T6993 |
amod |
temporal,lobe |
R3132 |
T6993 |
T6994 |
compound |
lobe,epilepsia |
R3133 |
T6994 |
T6991 |
pobj |
epilepsia,from |
R3134 |
T6995 |
T6966 |
punct |
.,explained |
R3135 |
T6997 |
T6998 |
prep |
On,was |
R3136 |
T6999 |
T7000 |
det |
the,hand |
R3137 |
T7000 |
T6997 |
pobj |
hand,On |
R3138 |
T7001 |
T7000 |
amod |
other,hand |
R3139 |
T7002 |
T7003 |
det |
the,tissue |
R3140 |
T7003 |
T6998 |
nsubj |
tissue,was |
R3141 |
T7004 |
T7003 |
amod |
actual,tissue |
R3142 |
T7005 |
T7003 |
amod |
human,tissue |
R3143 |
T7006 |
T7003 |
compound |
brain,tissue |
R3144 |
T7007 |
T7003 |
acl |
used,tissue |
R3145 |
T7008 |
T6998 |
prep |
from,was |
R3146 |
T7009 |
T7010 |
amod |
aged,patients |
R3147 |
T7010 |
T7008 |
pobj |
patients,from |
R3148 |
T7011 |
T6998 |
cc |
and,was |
R3149 |
T7012 |
T7013 |
aux |
did,correspond |
R3150 |
T7013 |
T6998 |
conj |
correspond,was |
R3151 |
T7014 |
T7013 |
neg |
not,correspond |
R3152 |
T7015 |
T7013 |
prep |
to,correspond |
R3153 |
T7016 |
T7017 |
det |
the,age |
R3154 |
T7017 |
T7015 |
pobj |
age,to |
R3155 |
T7018 |
T7017 |
prep |
of,age |
R3156 |
T7019 |
T7020 |
det |
the,mice |
R3157 |
T7020 |
T7018 |
pobj |
mice,of |
R3158 |
T7021 |
T7020 |
acl |
included,mice |
R3159 |
T7022 |
T7021 |
prep |
in,included |
R3160 |
T7023 |
T7024 |
det |
this,study |
R3161 |
T7024 |
T7022 |
pobj |
study,in |
R3162 |
T7025 |
T6998 |
punct |
.,was |
R3163 |
T7027 |
T7028 |
prep |
In,translocated |
R3164 |
T7029 |
T7030 |
amod |
cultured,cells |
R3165 |
T7030 |
T7027 |
pobj |
cells,In |
R3166 |
T7031 |
T7028 |
prep |
after,translocated |
R3167 |
T7032 |
T7033 |
compound |
cell,damage |
R3168 |
T7033 |
T7031 |
pobj |
damage,after |
R3169 |
T7034 |
T7033 |
cc |
or,damage |
R3170 |
T7035 |
T7033 |
conj |
apoptosis,damage |
R3171 |
T7036 |
T7037 |
punct |
(,observations |
R3172 |
T7037 |
T7035 |
meta |
observations,apoptosis |
R3173 |
T7038 |
T7037 |
amod |
unpublished,observations |
R3174 |
T7039 |
T7037 |
punct |
),observations |
R3175 |
T7040 |
T7031 |
cc |
or,after |
R3176 |
T7041 |
T7031 |
conj |
in,after |
R3177 |
T7042 |
T7041 |
pobj |
cells,in |
R3178 |
T7043 |
T7042 |
acl |
treated,cells |
R3179 |
T7044 |
T7043 |
prep |
with,treated |
R3180 |
T7045 |
T7046 |
det |
a,ionophore |
R3181 |
T7046 |
T7044 |
pobj |
ionophore,with |
R3182 |
T7047 |
T7046 |
compound |
Ca2+,ionophore |
R3183 |
T7048 |
T7046 |
punct |
-,ionophore |
R3184 |
T7049 |
T7050 |
compound |
Annexin,A7 |
R3185 |
T7050 |
T7028 |
nsubj |
A7,translocated |
R3186 |
T7051 |
T7028 |
prep |
from,translocated |
R3187 |
T7052 |
T7053 |
det |
the,cytoplasm |
R3188 |
T7053 |
T7051 |
pobj |
cytoplasm,from |
R3189 |
T7054 |
T7028 |
prep |
to,translocated |
R3190 |
T7055 |
T7056 |
amod |
cellular,membranes |
R3191 |
T7056 |
T7054 |
pobj |
membranes,to |
R3192 |
T7057 |
T7058 |
punct |
[,19 |
R3193 |
T7058 |
T7028 |
parataxis |
19,translocated |
R3194 |
T7059 |
T7058 |
punct |
],19 |
R3195 |
T7060 |
T7028 |
punct |
.,translocated |
R3196 |
T7062 |
T7063 |
nsubj |
We,favor |
R3197 |
T7064 |
T7063 |
advmod |
therefore,favor |
R3198 |
T7065 |
T7066 |
det |
the,hypothesis |
R3199 |
T7066 |
T7063 |
dobj |
hypothesis,favor |
R3200 |
T7067 |
T7068 |
mark |
that,translocated |
R3201 |
T7068 |
T7066 |
acl |
translocated,hypothesis |
R3202 |
T7069 |
T7070 |
compound |
Annexin,A7 |
R3203 |
T7070 |
T7068 |
nsubj |
A7,translocated |
R3204 |
T7071 |
T7070 |
prep |
in,A7 |
R3205 |
T7072 |
T7073 |
det |
the,neurons |
R3206 |
T7073 |
T7071 |
pobj |
neurons,in |
R3207 |
T7074 |
T7073 |
amod |
sensitive,neurons |
R3208 |
T7075 |
T7073 |
prep |
of,neurons |
R3209 |
T7076 |
T7077 |
det |
the,brain |
R3210 |
T7077 |
T7075 |
pobj |
brain,of |
R3211 |
T7078 |
T7077 |
amod |
human,brain |
R3212 |
T7079 |
T7077 |
compound |
autopsy,brain |
R3213 |
T7080 |
T7068 |
aux |
may,translocated |
R3214 |
T7081 |
T7068 |
aux |
have,translocated |
R3215 |
T7082 |
T7068 |
advmod |
similarly,translocated |
R3216 |
T7083 |
T7068 |
prep |
to,translocated |
R3217 |
T7084 |
T7085 |
det |
the,membrane |
R3218 |
T7085 |
T7083 |
pobj |
membrane,to |
R3219 |
T7086 |
T7085 |
amod |
cellular,membrane |
R3220 |
T7087 |
T7063 |
punct |
.,favor |
R3221 |
T7089 |
T7090 |
det |
This,property |
R3222 |
T7090 |
T7091 |
nsubj |
property,is |
R3223 |
T7092 |
T7090 |
prep |
of,property |
R3224 |
T7093 |
T7092 |
pobj |
translocation,of |
R3225 |
T7094 |
T7093 |
cc |
and,translocation |
R3226 |
T7095 |
T7096 |
compound |
membrane,binding |
R3227 |
T7096 |
T7093 |
conj |
binding,translocation |
R3228 |
T7097 |
T7091 |
acomp |
common,is |
R3229 |
T7098 |
T7097 |
prep |
to,common |
R3230 |
T7099 |
T7100 |
det |
all,annexins |
R3231 |
T7100 |
T7098 |
pobj |
annexins,to |
R3232 |
T7101 |
T7091 |
cc |
and,is |
R3233 |
T7102 |
T7103 |
advmod |
commercially,available |
R3234 |
T7103 |
T7104 |
amod |
available,kits |
R3235 |
T7104 |
T7105 |
nsubj |
kits,employ |
R3236 |
T7105 |
T7091 |
conj |
employ,is |
R3237 |
T7106 |
T7104 |
prep |
for,kits |
R3238 |
T7107 |
T7108 |
compound |
apoptosis,detection |
R3239 |
T7108 |
T7106 |
pobj |
detection,for |
R3240 |
T7109 |
T7110 |
amod |
recombinant,AnnexinA5 |
R3241 |
T7110 |
T7105 |
dobj |
AnnexinA5,employ |
R3242 |
T7111 |
T7105 |
punct |
.,employ |
R3243 |
T7113 |
T7114 |
det |
The,presence |
R3244 |
T7114 |
T7115 |
nsubjpass |
presence,confirmed |
R3245 |
T7116 |
T7114 |
prep |
of,presence |
R3246 |
T7117 |
T7118 |
amod |
nuclear,A7 |
R3247 |
T7118 |
T7116 |
pobj |
A7,of |
R3248 |
T7119 |
T7118 |
compound |
Annexin,A7 |
R3249 |
T7120 |
T7114 |
prep |
in,presence |
R3250 |
T7121 |
T7122 |
amod |
murine,brain |
R3251 |
T7122 |
T7120 |
pobj |
brain,in |
R3252 |
T7123 |
T7115 |
auxpass |
was,confirmed |
R3253 |
T7124 |
T7115 |
prep |
by,confirmed |
R3254 |
T7125 |
T7124 |
pobj |
controls,by |
R3255 |
T7126 |
T7125 |
acl |
using,controls |
R3256 |
T7127 |
T7126 |
dobj |
sections,using |
R3257 |
T7128 |
T7127 |
prep |
from,sections |
R3258 |
T7129 |
T7130 |
det |
the,mouse |
R3259 |
T7130 |
T7128 |
pobj |
mouse,from |
R3260 |
T7131 |
T7130 |
nmod |
AnxA7,mouse |
R3261 |
T7132 |
T7131 |
punct |
-,AnxA7 |
R3262 |
T7133 |
T7131 |
punct |
/,AnxA7 |
R3263 |
T7134 |
T7131 |
punct |
-,AnxA7 |
R3264 |
T7135 |
T7124 |
cc |
and,by |
R3265 |
T7136 |
T7124 |
conj |
by,by |
R3266 |
T7137 |
T7138 |
det |
a,extraction |
R3267 |
T7138 |
T7136 |
pobj |
extraction,by |
R3268 |
T7139 |
T7138 |
amod |
biochemical,extraction |
R3269 |
T7140 |
T7138 |
prep |
of,extraction |
R3270 |
T7141 |
T7142 |
det |
the,protein |
R3271 |
T7142 |
T7140 |
pobj |
protein,of |
R3272 |
T7143 |
T7138 |
prep |
from,extraction |
R3273 |
T7144 |
T7145 |
det |
the,nucleus |
R3274 |
T7145 |
T7143 |
pobj |
nucleus,from |
R3275 |
T7146 |
T7115 |
punct |
.,confirmed |
R3276 |
T7148 |
T7149 |
det |
Both,isoforms |
R3277 |
T7149 |
T7152 |
nsubjpass |
isoforms,expressed |
R3278 |
T7150 |
T7151 |
compound |
Annexin,A7 |
R3279 |
T7151 |
T7149 |
compound |
A7,isoforms |
R3280 |
T7153 |
T7149 |
acl |
described,isoforms |
R3281 |
T7154 |
T7153 |
prep |
in,described |
R3282 |
T7155 |
T7156 |
compound |
brain,tissue |
R3283 |
T7156 |
T7154 |
pobj |
tissue,in |
R3284 |
T7157 |
T7152 |
advmod |
seemingly,expressed |
R3285 |
T7158 |
T7152 |
auxpass |
are,expressed |
R3286 |
T7159 |
T7152 |
agent |
by,expressed |
R3287 |
T7160 |
T7159 |
pobj |
neurons,by |
R3288 |
T7161 |
T7160 |
cc |
and,neurons |
R3289 |
T7162 |
T7160 |
conj |
astrocytes,neurons |
R3290 |
T7163 |
T7152 |
punct |
", ",expressed |
R3291 |
T7164 |
T7165 |
dep |
which,shown |
R3292 |
T7165 |
T7152 |
advcl |
shown,expressed |
R3293 |
T7166 |
T7165 |
auxpass |
was,shown |
R3294 |
T7167 |
T7165 |
advcl |
using,shown |
R3295 |
T7168 |
T7169 |
amod |
total,extracts |
R3296 |
T7169 |
T7167 |
dobj |
extracts,using |
R3297 |
T7170 |
T7169 |
compound |
cell,extracts |
R3298 |
T7171 |
T7169 |
prep |
of,extracts |
R3299 |
T7172 |
T7173 |
amod |
cultured,cells |
R3300 |
T7173 |
T7171 |
pobj |
cells,of |
R3301 |
T7174 |
T7173 |
nmod |
neuo,cells |
R3302 |
T7175 |
T7174 |
punct |
-,neuo |
R3303 |
T7176 |
T7174 |
nummod |
2a,neuo |
R3304 |
T7177 |
T7174 |
punct |
", ",neuo |
R3305 |
T7178 |
T7174 |
conj |
PC,neuo |
R3306 |
T7179 |
T7178 |
punct |
-,PC |
R3307 |
T7180 |
T7178 |
nummod |
12,PC |
R3308 |
T7181 |
T7178 |
punct |
", ",PC |
R3309 |
T7182 |
T7178 |
cc |
and,PC |
R3310 |
T7183 |
T7178 |
conj |
C6,PC |
R3311 |
T7184 |
T7152 |
punct |
.,expressed |
R3312 |
T7186 |
T7187 |
prep |
In,described |
R3313 |
T7188 |
T7186 |
pobj |
addition,In |
R3314 |
T7189 |
T7188 |
prep |
to,addition |
R3315 |
T7190 |
T7191 |
poss |
their,expression |
R3316 |
T7191 |
T7189 |
pobj |
expression,to |
R3317 |
T7192 |
T7191 |
prep |
in,expression |
R3318 |
T7193 |
T7192 |
pobj |
brain,in |
R3319 |
T7194 |
T7187 |
punct |
", ",described |
R3320 |
T7195 |
T7196 |
preconj |
both,isoforms |
R3321 |
T7196 |
T7187 |
nsubjpass |
isoforms,described |
R3322 |
T7197 |
T7198 |
compound |
Annexin,A7 |
R3323 |
T7198 |
T7196 |
compound |
A7,isoforms |
R3324 |
T7199 |
T7187 |
aux |
have,described |
R3325 |
T7200 |
T7187 |
advmod |
only,described |
R3326 |
T7201 |
T7187 |
auxpass |
been,described |
R3327 |
T7202 |
T7187 |
prep |
in,described |
R3328 |
T7203 |
T7204 |
compound |
heart,muscle |
R3329 |
T7204 |
T7202 |
pobj |
muscle,in |
R3330 |
T7205 |
T7204 |
cc |
and,muscle |
R3331 |
T7206 |
T7207 |
amod |
red,cells |
R3332 |
T7207 |
T7204 |
conj |
cells,muscle |
R3333 |
T7208 |
T7207 |
compound |
blood,cells |
R3334 |
T7209 |
T7210 |
punct |
[,5 |
R3335 |
T7210 |
T7187 |
parataxis |
5,described |
R3336 |
T7211 |
T7212 |
punct |
-,8 |
R3337 |
T7212 |
T7210 |
prep |
8,5 |
R3338 |
T7213 |
T7210 |
punct |
],5 |
R3339 |
T7214 |
T7187 |
punct |
.,described |