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(A) Pyramidal neurons (bold arrow) and apical dendrites (small arrows) were clearly labeled with the antibody against Annexin A7 in the human parietal cortex. (B) A dendritic staining was also seen in the molecular layer (small arrows). In addition the subpial astrocytes were weakly labeled (double headed arrows). The staining was cytoplasmic, only few astrocytes showed a nuclear staining as well (inset). (C) Enlargement of (A): Annexin A7 was seen at the cell membrane of the perikaryon (bold arrow) and the apical dendrite (small arrows). (D) A blank control lacking the primary antibody did not show a specific labeling, but autofluorescent lipofuscin was detectable in the neurons (arrowheads). Bar, (A) 70 μm, (B) 50 μm, (B-inset, C) 17 μm, (D) 20 μm."}

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