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craft-sa-dev

Id Subject Object Predicate Lexical cue
T3885 0-1992 sentence denotes Figure 1 Replacement of Er81 by EWS-Pea3 (A) Generation of Er81EWS-Pea3 mutant mice. Above is the organization of the Er81 genomic locus in the region targeted by homologous recombination in analogy to [14]. Exons 1–4 are shown as light blue boxes, and the Er81 start codon in exon 2 is indicated as ATG. The probe used to detect homologous recombination is shown as a grey box. Below is replacement of Er81 by EWS-Pea3 through the integration of EWS-Pea3 in frame with the endogenous start codon of the Er81 locus in exon 2 (in analogy to [14]). (B) PCR and Southern blot analysis of Er81EWS-Pea3 wild-type (+/+), heterozygous (+/−), and homozygous (−/−) genomic DNA to detect the mutant allele. PCR primer pairs (EWS-Pea3ki) were used to detect specifically the recombined allele, and a primer pair in exon2 was used to detect the presence of the wild-type allele [14]. (C–E) Analysis of Er81 expression in lumbar DRG neurons of E16.5 wild-type (C), Er81−/− (D), and Er81EWS-Pea3/− (E) embryos. Inset in lower right corner of each panel shows Isl1 expression in the respective DRG. (F–H) PV expression in lumbar DRG of E16.5 wild-type (F), Er81−/− (G), and Er81EWS-Pea3/− (H) embryos. Confocal scans were performed with equal gain intensity. (J) Transcriptional transactivation of luciferase expression from a minimal reporter construct containing five consensus ETS DNA-binding sites ( GCCGGAAGC; [18,19]) and a minimal TK promoter upon transient transfection of Er81 (n ≥ 7; 3.03 ± 0.66) or EWS-Pea3 (n ≥ 7; 20.3 ± 2.7). Relative luciferase activity normalized to control (Con). Scale bar: 80 μm. Expression of Er81 in DRG neurons of embryos containing integration of EWS-Pea3 in the Er81 locus (Er81EWS-Pea3/−) was abolished (Figure 1E), and the expression level of the calcium-binding protein Parvalbumin (PV) in proprioceptive afferents, which is decreased approximately 5- to 10-fold in Er81 mutants [14], was comparable to wild-type levels in Er81EWS-Pea3/− embryos (Figure 1F–1H).
T3886 1603-1613 NN denotes Expression
T3887 1722-1731 VBN denotes abolished
T3888 1614-1616 IN denotes of
T3889 1617-1621 NN denotes Er81
T3890 1622-1624 IN denotes in
T3891 1625-1628 NN denotes DRG
T3892 1629-1636 NNS denotes neurons
T3893 1637-1639 IN denotes of
T3894 1640-1647 NNS denotes embryos
T3895 1648-1658 VBG denotes containing
T3896 1659-1670 NN denotes integration
T3897 1671-1673 IN denotes of
T3898 1674-1677 NN denotes EWS
T3899 1678-1682 NN denotes Pea3
T3900 1677-1678 HYPH denotes -
T3901 1683-1685 IN denotes in
T3902 1686-1689 DT denotes the
T3903 1695-1700 NN denotes locus
T3904 1690-1694 NN denotes Er81
T3905 1701-1702 -LRB- denotes (
T3906 1702-1709 NN denotes Er81EWS
T3907 1710-1714 NN denotes Pea3
T3908 1709-1710 HYPH denotes -
T3909 1714-1715 HYPH denotes /
T3910 1715-1716 SYM denotes −
T3911 1716-1717 -RRB- denotes )
T3912 1718-1721 VBD denotes was
T3913 1732-1733 -LRB- denotes (
T3914 1740-1742 NN denotes 1E
T3915 1733-1739 NN denotes Figure
T3916 1742-1743 -RRB- denotes )
T3917 1743-1745 , denotes ,
T3918 1745-1748 CC denotes and
T3919 1749-1752 DT denotes the
T3920 1764-1769 NN denotes level
T3921 1753-1763 NN denotes expression
T3922 1916-1919 VBD denotes was
T3923 1770-1772 IN denotes of
T3924 1773-1776 DT denotes the
T3925 1793-1800 NN denotes protein
T3926 1777-1784 NN denotes calcium
T3927 1785-1792 VBG denotes binding
T3928 1784-1785 HYPH denotes -
T3929 1801-1812 NN denotes Parvalbumin
T3930 1813-1814 -LRB- denotes (
T3931 1814-1816 NN denotes PV
T3932 1816-1817 -RRB- denotes )
T3933 1818-1820 IN denotes in
T3934 1821-1835 JJ denotes proprioceptive
T3935 1836-1845 NNS denotes afferents
T3936 1845-1847 , denotes ,
T3937 1847-1852 WDT denotes which
T3938 1856-1865 VBN denotes decreased
T3939 1853-1855 VBZ denotes is
T3940 1866-1879 RB denotes approximately
T3941 1886-1888 CD denotes 10
T3942 1880-1881 CD denotes 5
T3943 1881-1882 HYPH denotes -
T3944 1883-1885 IN denotes to
T3945 1889-1893 RB denotes fold
T3946 1888-1889 HYPH denotes -
T3947 1894-1896 IN denotes in
T3948 1897-1901 NN denotes Er81
T3949 1902-1909 NNS denotes mutants
T3950 1910-1911 -LRB- denotes [
T3951 1911-1913 CD denotes 14
T3952 1913-1914 -RRB- denotes ]
T3953 1914-1916 , denotes ,
T3954 1920-1930 JJ denotes comparable
T3955 1931-1933 IN denotes to
T3956 1934-1938 JJ denotes wild
T3957 1939-1943 NN denotes type
T3958 1938-1939 HYPH denotes -
T3959 1944-1950 NNS denotes levels
T3960 1951-1953 IN denotes in
T3961 1954-1961 NN denotes Er81EWS
T3962 1962-1966 NN denotes Pea3
T3963 1961-1962 HYPH denotes -
T3964 1969-1976 NNS denotes embryos
T3965 1966-1967 HYPH denotes /
T3966 1967-1968 SYM denotes −
T3967 1977-1978 -LRB- denotes (
T3968 1985-1987 NN denotes 1F
T3969 1978-1984 NN denotes Figure
T3970 1987-1988 SYM denotes –
T3971 1988-1990 NN denotes 1H
T3972 1990-1991 -RRB- denotes )
T3973 1991-1992 . denotes .
R1262 T3886 T3887 nsubjpass Expression,abolished
R1263 T3888 T3886 prep of,Expression
R1264 T3889 T3888 pobj Er81,of
R1265 T3890 T3886 prep in,Expression
R1266 T3891 T3892 compound DRG,neurons
R1267 T3892 T3890 pobj neurons,in
R1268 T3893 T3892 prep of,neurons
R1269 T3894 T3893 pobj embryos,of
R1270 T3895 T3894 acl containing,embryos
R1271 T3896 T3895 dobj integration,containing
R1272 T3897 T3896 prep of,integration
R1273 T3898 T3899 compound EWS,Pea3
R1274 T3899 T3897 pobj Pea3,of
R1275 T3900 T3899 punct -,Pea3
R1276 T3901 T3886 prep in,Expression
R1277 T3902 T3903 det the,locus
R1278 T3903 T3901 pobj locus,in
R1279 T3904 T3903 compound Er81,locus
R1280 T3905 T3903 punct (,locus
R1281 T3906 T3907 compound Er81EWS,Pea3
R1282 T3907 T3903 appos Pea3,locus
R1283 T3908 T3907 punct -,Pea3
R1284 T3909 T3907 punct /,Pea3
R1285 T3910 T3907 punct −,Pea3
R1286 T3911 T3887 punct ),abolished
R1287 T3912 T3887 auxpass was,abolished
R1288 T3913 T3914 punct (,1E
R1289 T3914 T3887 parataxis 1E,abolished
R1290 T3915 T3914 compound Figure,1E
R1291 T3916 T3914 punct ),1E
R1292 T3917 T3887 punct ", ",abolished
R1293 T3918 T3887 cc and,abolished
R1294 T3919 T3920 det the,level
R1295 T3920 T3922 nsubj level,was
R1296 T3921 T3920 compound expression,level
R1297 T3922 T3887 conj was,abolished
R1298 T3923 T3920 prep of,level
R1299 T3924 T3925 det the,protein
R1300 T3925 T3923 pobj protein,of
R1301 T3926 T3927 npadvmod calcium,binding
R1302 T3927 T3925 amod binding,protein
R1303 T3928 T3927 punct -,binding
R1304 T3929 T3925 appos Parvalbumin,protein
R1305 T3930 T3929 punct (,Parvalbumin
R1306 T3931 T3929 appos PV,Parvalbumin
R1307 T3932 T3920 punct ),level
R1308 T3933 T3920 prep in,level
R1309 T3934 T3935 amod proprioceptive,afferents
R1310 T3935 T3933 pobj afferents,in
R1311 T3936 T3920 punct ", ",level
R1312 T3937 T3938 dep which,decreased
R1313 T3938 T3920 relcl decreased,level
R1314 T3939 T3938 auxpass is,decreased
R1315 T3940 T3941 advmod approximately,10
R1316 T3941 T3945 quantmod 10,fold
R1317 T3942 T3941 quantmod 5,10
R1318 T3943 T3941 punct -,10
R1319 T3944 T3941 quantmod to,10
R1320 T3945 T3938 advmod fold,decreased
R1321 T3946 T3945 punct -,fold
R1322 T3947 T3938 prep in,decreased
R1323 T3948 T3949 compound Er81,mutants
R1324 T3949 T3947 pobj mutants,in
R1325 T3950 T3951 punct [,14
R1326 T3951 T3938 parataxis 14,decreased
R1327 T3952 T3951 punct ],14
R1328 T3953 T3922 punct ", ",was
R1329 T3954 T3922 acomp comparable,was
R1330 T3955 T3954 prep to,comparable
R1331 T3956 T3957 amod wild,type
R1332 T3957 T3959 compound type,levels
R1333 T3958 T3957 punct -,type
R1334 T3959 T3955 pobj levels,to
R1335 T3960 T3922 prep in,was
R1336 T3961 T3962 nmod Er81EWS,Pea3
R1337 T3962 T3964 nmod Pea3,embryos
R1338 T3963 T3962 punct -,Pea3
R1339 T3964 T3960 pobj embryos,in
R1340 T3965 T3962 punct /,Pea3
R1341 T3966 T3962 punct −,Pea3
R1342 T3967 T3968 punct (,1F
R1343 T3968 T3922 parataxis 1F,was
R1344 T3969 T3968 compound Figure,1F
R1345 T3970 T3971 punct –,1H
R1346 T3971 T3968 prep 1H,1F
R1347 T3972 T3968 punct ),1F
R1348 T3973 T3922 punct .,was

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3450 1603-1613 GO:0010467 denotes Expression
T3451 1617-1621 PR_EXT:000007223 denotes Er81
T3452 1625-1628 UBERON:0000044 denotes DRG
T3453 1629-1636 CL:0000540 denotes neurons
T3454 1640-1647 UBERON:0000922 denotes embryos
T3455 1674-1677 PR_EXT:000007243 denotes EWS
T3456 1678-1682 PR_EXT:000007227 denotes Pea3
T3457 1690-1694 PR_EXT:000007223 denotes Er81
T3458 1702-1706 PR_EXT:000007223 denotes Er81
T3459 1706-1709 PR_EXT:000007243 denotes EWS
T3460 1710-1714 PR_EXT:000007227 denotes Pea3
T3461 1715-1716 SO_EXT:sequence_nullness_or_absence denotes −
T3462 1753-1763 GO:0010467 denotes expression
T3463 1777-1784 CHEBI_EXT:calcium denotes calcium
T3464 1785-1792 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T3465 1793-1800 CHEBI_PR_EXT:protein denotes protein
T3466 1801-1812 PR_EXT:000013502 denotes Parvalbumin
T3467 1814-1816 PR_EXT:000013502 denotes PV
T3468 1821-1835 GO:0019230 denotes proprioceptive
T3469 1897-1901 PR_EXT:000007223 denotes Er81
T3470 1902-1909 SO_EXT:sequence_altered_entity denotes mutants
T3471 1934-1943 SO_EXT:wild_type_entity_or_quality denotes wild-type
T3472 1954-1958 PR_EXT:000007223 denotes Er81
T3473 1958-1961 PR_EXT:000007243 denotes EWS
T3474 1962-1966 PR_EXT:000007227 denotes Pea3
T3475 1967-1968 SO_EXT:sequence_nullness_or_absence denotes −
T3476 1969-1976 UBERON:0000922 denotes embryos

2_test

Id Subject Object Predicate Lexical cue
15836427-10850491-84719628 205-207 10850491 denotes 14
15836427-10850491-84719629 543-545 10850491 denotes 14
15836427-10850491-84719630 869-871 10850491 denotes 14
15836427-9734357-84719631 1403-1405 9734357 denotes 18
15836427-11096072-84719632 1406-1408 11096072 denotes 19
15836427-10850491-84719633 1911-1913 10850491 denotes 14
T40480 205-207 10850491 denotes 14
T21606 543-545 10850491 denotes 14
T94600 869-871 10850491 denotes 14
T96846 1403-1405 9734357 denotes 18
T64151 1406-1408 11096072 denotes 19
T5880 1911-1913 10850491 denotes 14

biosemtest

Id Subject Object Predicate Lexical cue
T2737 1885-1887 UMLS/C0319022 denotes 1
T2738 1933-1935 UMLS/C0319022 denotes w
T2747 1625-1628 UMLS/C1537672 denotes DRG
T2757 1803-1814 UMLS/C0030616 denotes rvalbumin (
T2760 1936-1945 UMLS/C1883559 denotes ld-type l
T2772 1603-1613 UMLS/C0017262 denotes Expression
T2773 1755-1765 UMLS/C0017262 denotes pression l
T2805 1779-1802 UP/P06495 denotes lcium-binding protein P
T2810 1904-1911 UMLS/C0596988 denotes tants [
T2825 1603-1613 UMLS/C0185117 denotes Expression
T2826 1755-1765 UMLS/C0185117 denotes pression l
T2835 1766-1771 UMLS/C0441889 denotes vel o
T2836 1946-1952 UMLS/C0441889 denotes vels i
T2843 1803-1814 UP/P35491 denotes rvalbumin (
T2845 1766-1771 UMLS/C0456079 denotes vel o
T2846 1946-1952 UMLS/C0456079 denotes vels i
T2858 1858-1867 UMLS/C0442797 denotes creased a
T2892 1779-1802 UMLS/C0006732 denotes lcium-binding protein P
T2914 1640-1647 UMLS/C0013935 denotes embryos
T2915 1973-1980 UMLS/C0013935 denotes yos (Fi
T2918 1858-1867 UMLS/C0205216 denotes creased a
T2931 1648-1658 UMLS/C1549781 denotes containing
T2938 1648-1658 UMLS/C2700400 denotes containing
T2956 1648-1658 UMLS/C0332256 denotes containing
T2957 1803-1814 UMLS/C1419140 denotes rvalbumin (
T2963 1779-1802 UP/P13566 denotes lcium-binding protein P
T2965 1625-1628 UMLS/C0011928 denotes DRG
T2973 1868-1881 UMLS/C0332232 denotes proximately 5
T2978 1838-1847 UMLS/C0205115 denotes ferents,
T3015 1858-1867 UMLS/C0392756 denotes creased a
T3037 1779-1802 UP/P38505 denotes lcium-binding protein P
T3053 1695-1700 UMLS/C1708726 denotes locus
T3067 1858-1867 UMLS/C0547047 denotes creased a
T3092 1640-1647 UMLS/C1305370 denotes embryos
T3093 1973-1980 UMLS/C1305370 denotes yos (Fi
T3115 1629-1636 UMLS/C0027882 denotes neurons
T3142 1625-1628 UMLS/C1414151 denotes DRG
T3151 1659-1670 UMLS/C1158478 denotes integration
T3196 1659-1670 UMLS/C1705422 denotes integration
T3221 1779-1802 UMLS/C1822659 denotes lcium-binding protein P
T3222 1779-1802 UP/O42720 denotes lcium-binding protein P

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3267 1603-1613 GO:0010467 denotes Expression
T3268 1617-1621 PR:000007223 denotes Er81
T3269 1625-1628 UBERON:0000044 denotes DRG
T3270 1629-1636 CL:0000540 denotes neurons
T3271 1640-1647 UBERON:0000922 denotes embryos
T3272 1674-1677 PR:000007243 denotes EWS
T3273 1678-1682 PR:000007227 denotes Pea3
T3274 1690-1694 PR:000007223 denotes Er81
T3275 1702-1706 PR:000007223 denotes Er81
T3276 1706-1709 PR:000007243 denotes EWS
T3277 1710-1714 PR:000007227 denotes Pea3
T3278 1753-1763 GO:0010467 denotes expression
T3279 1801-1812 PR:000013502 denotes Parvalbumin
T3280 1814-1816 PR:000013502 denotes PV
T3281 1821-1835 GO:0019230 denotes proprioceptive
T3282 1897-1901 PR:000007223 denotes Er81
T3283 1954-1958 PR:000007223 denotes Er81
T3284 1958-1961 PR:000007243 denotes EWS
T3285 1962-1966 PR:000007227 denotes Pea3
T3286 1969-1976 UBERON:0000922 denotes embryos