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PMC:1084331 / 229-1059 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T289 5-7 IN denotes of
T290 8-14 JJ denotes dorsal
T291 20-28 NN denotes ganglion
T292 15-19 NN denotes root
T293 60-67 NNS denotes neurons
T294 29-30 -LRB- denotes (
T295 30-33 NN denotes DRG
T296 33-34 -RRB- denotes )
T297 35-42 JJ denotes sensory
T298 43-46 CC denotes and
T299 47-53 JJ denotes spinal
T300 54-59 NN denotes motor
T301 68-70 IN denotes by
T302 71-77 NN denotes target
T303 78-85 VBN denotes derived
T304 77-78 HYPH denotes -
T305 86-93 NNS denotes factors
T306 93-94 . denotes .
T307 94-200 sentence denotes Their expression controls late aspects of neuronal differentiation such as target invasion and branching.
T308 95-100 PRP$ denotes Their
T309 101-111 NN denotes expression
T310 112-120 VBZ denotes controls
T311 121-125 JJ denotes late
T312 126-133 NNS denotes aspects
T313 134-136 IN denotes of
T314 137-145 JJ denotes neuronal
T315 146-161 NN denotes differentiation
T316 162-166 JJ denotes such
T317 167-169 IN denotes as
T318 170-176 NN denotes target
T319 177-185 NN denotes invasion
T320 186-189 CC denotes and
T321 190-199 NN denotes branching
T322 199-200 . denotes .
T323 200-328 sentence denotes Here, we show that the late onset of ETS gene expression is an essential requirement for normal sensory neuron differentiation.
T324 201-205 RB denotes Here
T325 210-214 VBP denotes show
T326 205-207 , denotes ,
T327 207-209 PRP denotes we
T328 215-219 IN denotes that
T329 258-260 VBZ denotes is
T330 220-223 DT denotes the
T331 229-234 NN denotes onset
T332 224-228 JJ denotes late
T333 235-237 IN denotes of
T334 238-241 NN denotes ETS
T335 242-246 NN denotes gene
T336 247-257 NN denotes expression
T337 261-263 DT denotes an
T338 274-285 NN denotes requirement
T339 264-273 JJ denotes essential
T340 286-289 IN denotes for
T341 290-296 JJ denotes normal
T342 312-327 NN denotes differentiation
T343 297-304 JJ denotes sensory
T344 305-311 NN denotes neuron
T345 327-328 . denotes .
T346 328-551 sentence denotes We provide genetic evidence in the mouse that precocious ETS expression in DRG sensory neurons perturbs axonal projections, the acquisition of terminal differentiation markers, and their dependence on neurotrophic support.
T347 329-331 PRP denotes We
T348 332-339 VBP denotes provide
T349 340-347 JJ denotes genetic
T350 348-356 NN denotes evidence
T351 357-359 IN denotes in
T352 360-363 DT denotes the
T353 364-369 NN denotes mouse
T354 370-374 IN denotes that
T355 424-432 VBZ denotes perturbs
T356 375-385 JJ denotes precocious
T357 390-400 NN denotes expression
T358 386-389 NN denotes ETS
T359 401-403 IN denotes in
T360 404-407 NN denotes DRG
T361 416-423 NNS denotes neurons
T362 408-415 JJ denotes sensory
T363 433-439 JJ denotes axonal
T364 440-451 NNS denotes projections
T365 451-453 , denotes ,
T366 453-456 DT denotes the
T367 457-468 NN denotes acquisition
T368 469-471 IN denotes of
T369 472-480 JJ denotes terminal
T370 497-504 NNS denotes markers
T371 481-496 NN denotes differentiation
T372 504-506 , denotes ,
T373 506-509 CC denotes and
T374 510-515 PRP$ denotes their
T375 516-526 NN denotes dependence
T376 527-529 IN denotes on
T377 530-542 JJ denotes neurotrophic
T378 543-550 NN denotes support
T379 550-551 . denotes .
T380 551-773 sentence denotes Together, our findings indicate that DRG sensory neurons exhibit a temporal developmental switch that can be revealed by distinct responses to ETS transcription factor signaling at sequential steps of neuronal maturation.
T381 552-560 RB denotes Together
T382 575-583 VBP denotes indicate
T383 560-562 , denotes ,
T384 562-565 PRP$ denotes our
T385 566-574 NNS denotes findings
T386 584-588 IN denotes that
T387 609-616 VBP denotes exhibit
T388 589-592 NN denotes DRG
T389 601-608 NNS denotes neurons
T390 593-600 JJ denotes sensory
T391 617-618 DT denotes a
T392 642-648 NN denotes switch
T393 619-627 JJ denotes temporal
T394 628-641 JJ denotes developmental
T395 649-653 WDT denotes that
T396 661-669 VBN denotes revealed
T397 654-657 MD denotes can
T398 658-660 VB denotes be
T399 670-672 IN denotes by
T400 673-681 JJ denotes distinct
T401 682-691 NNS denotes responses
T402 692-694 IN denotes to
T403 695-698 NN denotes ETS
T404 720-729 NN denotes signaling
T405 699-712 NN denotes transcription
T406 713-719 NN denotes factor
T407 730-732 IN denotes at
T408 733-743 JJ denotes sequential
T409 744-749 NNS denotes steps
T410 750-752 IN denotes of
T411 753-761 JJ denotes neuronal
T412 762-772 NN denotes maturation
T413 772-773 . denotes .
R91 T356 T357 amod precocious,expression
R31 T290 T291 amod dorsal,ganglion
R32 T291 T293 nmod ganglion,neurons
R33 T292 T291 nmod root,ganglion
R34 T293 T289 pobj neurons,of
R35 T294 T291 punct (,ganglion
R36 T295 T291 appos DRG,ganglion
R37 T296 T291 punct ),ganglion
R38 T297 T293 amod sensory,neurons
R39 T298 T297 cc and,sensory
R40 T299 T300 amod spinal,motor
R41 T300 T297 conj motor,sensory
R43 T302 T303 npadvmod target,derived
R44 T303 T305 amod derived,factors
R45 T304 T303 punct -,derived
R46 T305 T301 pobj factors,by
R48 T308 T309 poss Their,expression
R49 T309 T310 nsubj expression,controls
R50 T311 T312 amod late,aspects
R51 T312 T310 dobj aspects,controls
R52 T313 T312 prep of,aspects
R53 T314 T315 amod neuronal,differentiation
R54 T315 T313 pobj differentiation,of
R55 T316 T317 amod such,as
R56 T317 T312 prep as,aspects
R57 T318 T319 compound target,invasion
R58 T319 T317 pobj invasion,as
R59 T320 T319 cc and,invasion
R60 T321 T319 conj branching,invasion
R61 T322 T310 punct .,controls
R62 T324 T325 advmod Here,show
R63 T326 T325 punct ", ",show
R64 T327 T325 nsubj we,show
R65 T328 T329 mark that,is
R66 T329 T325 ccomp is,show
R67 T330 T331 det the,onset
R68 T331 T329 nsubj onset,is
R69 T332 T331 amod late,onset
R70 T333 T331 prep of,onset
R71 T334 T335 compound ETS,gene
R72 T335 T336 compound gene,expression
R73 T336 T333 pobj expression,of
R74 T337 T338 det an,requirement
R75 T338 T329 attr requirement,is
R76 T339 T338 amod essential,requirement
R77 T340 T338 prep for,requirement
R78 T341 T342 amod normal,differentiation
R79 T342 T340 pobj differentiation,for
R80 T343 T344 amod sensory,neuron
R81 T344 T342 compound neuron,differentiation
R82 T345 T325 punct .,show
R83 T347 T348 nsubj We,provide
R84 T349 T350 amod genetic,evidence
R85 T350 T348 dobj evidence,provide
R86 T351 T348 prep in,provide
R87 T352 T353 det the,mouse
R88 T353 T351 pobj mouse,in
R89 T354 T355 mark that,perturbs
R90 T355 T348 ccomp perturbs,provide
R92 T357 T355 nsubj expression,perturbs
R93 T358 T357 compound ETS,expression
R94 T359 T357 prep in,expression
R95 T360 T361 nmod DRG,neurons
R96 T361 T359 pobj neurons,in
R97 T362 T361 amod sensory,neurons
R98 T363 T364 amod axonal,projections
R99 T364 T355 dobj projections,perturbs
R100 T365 T364 punct ", ",projections
R101 T366 T367 det the,acquisition
R102 T367 T364 conj acquisition,projections
R103 T368 T367 prep of,acquisition
R104 T369 T370 amod terminal,markers
R105 T370 T368 pobj markers,of
R106 T371 T370 compound differentiation,markers
R107 T372 T367 punct ", ",acquisition
R108 T373 T367 cc and,acquisition
R109 T374 T375 poss their,dependence
R110 T375 T367 conj dependence,acquisition
R111 T376 T375 prep on,dependence
R112 T377 T378 amod neurotrophic,support
R113 T378 T376 pobj support,on
R114 T379 T348 punct .,provide
R115 T381 T382 advmod Together,indicate
R116 T383 T382 punct ", ",indicate
R117 T384 T385 poss our,findings
R118 T385 T382 nsubj findings,indicate
R119 T386 T387 mark that,exhibit
R120 T387 T382 ccomp exhibit,indicate
R121 T388 T389 nmod DRG,neurons
R122 T389 T387 nsubj neurons,exhibit
R123 T390 T389 amod sensory,neurons
R124 T391 T392 det a,switch
R125 T392 T387 dobj switch,exhibit
R126 T393 T392 amod temporal,switch
R127 T394 T392 amod developmental,switch
R128 T395 T396 dep that,revealed
R129 T396 T392 relcl revealed,switch
R130 T397 T396 aux can,revealed
R131 T398 T396 auxpass be,revealed
R132 T399 T396 agent by,revealed
R133 T400 T401 amod distinct,responses
R134 T401 T399 pobj responses,by
R135 T402 T401 prep to,responses
R136 T403 T404 compound ETS,signaling
R137 T404 T402 pobj signaling,to
R138 T405 T406 compound transcription,factor
R139 T406 T404 compound factor,signaling
R140 T407 T401 prep at,responses
R141 T408 T409 amod sequential,steps
R142 T409 T407 pobj steps,at
R143 T410 T409 prep of,steps
R144 T411 T412 amod neuronal,maturation
R145 T412 T410 pobj maturation,of
R146 T413 T382 punct .,indicate

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T223 8-28 UBERON:0000044 denotes dorsal root ganglion
T224 8-28 _FRAGMENT denotes dorsal root ganglion
T225 35-42 _FRAGMENT denotes sensory
T226 60-67 CL:1001451 denotes neurons
T227 30-33 UBERON:0000044 denotes DRG
T228 30-33 _FRAGMENT denotes DRG
T229 35-42 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T230 47-53 UBERON:0001130 denotes spinal
T231 47-67 CL:0011001 denotes spinal motor neurons
T232 54-59 GO_EXT:biological_movement_or_translocation_process denotes motor
T233 101-111 GO:0010467 denotes expression
T234 112-120 GO:0065007 denotes controls
T235 137-145 CL:0000540 denotes neuronal
T236 146-161 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T237 242-246 SO_EXT:0000704 denotes gene
T238 242-257 GO:0010467 denotes gene expression
T239 297-311 CL:0000101 denotes sensory neuron
T240 312-327 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T241 340-347 SO_EXT:0000704 denotes genetic
T242 364-369 NCBITaxon:10088 denotes mouse
T243 390-400 GO:0010467 denotes expression
T244 404-407 UBERON:0000044 denotes DRG
T245 404-423 CL:1001451 denotes DRG sensory neurons
T246 408-415 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T247 433-451 GO:0030424 denotes axonal projections
T248 481-496 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T249 497-504 CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag denotes markers
T250 530-542 GO_EXT:neuron_development_or_generation denotes neurotrophic
T251 589-592 UBERON:0000044 denotes DRG
T252 589-608 CL:1001451 denotes DRG sensory neurons
T253 593-600 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T254 682-691 GO_EXT:reaction_or_response denotes responses
T255 699-712 GO_EXT:transcription denotes transcription
T256 699-719 GO_EXT:transcription_factor denotes transcription factor
T257 720-729 GO_EXT:cell_communication_or_signaling_or_signal_transduction denotes signaling
T258 753-761 CL:0000540 denotes neuronal
T259 753-772 GO:0042551 denotes neuronal maturation
R4 T225 T224 _lexicallyChainedTo sensory,dorsal root ganglion
R5 T225 T228 _lexicallyChainedTo sensory,DRG
R6 T226 T225 _lexicallyChainedTo neurons,sensory

biosemtest

Id Subject Object Predicate Lexical cue
T41 543-550 UMLS/C1521721 denotes support
T42 112-120 UMLS/C1882979 denotes controls
T43 112-120 UMLS/C1550141 denotes controls
T45 682-691 UMLS/C0871261 denotes responses
T47 642-648 UMLS/C1707719 denotes switch
T48 543-550 UMLS/C0183683 denotes support
T49 290-296 UMLS/C1551394 denotes normal
T50 619-627 UMLS/C0205374 denotes temporal
T51 472-480 UMLS/C0205088 denotes terminal
T52 609-616 UMLS/C0015272 denotes exhibit
T53 348-356 UMLS/C0332120 denotes evidence
T54 762-772 UMLS/C1254042 denotes maturation
T55 121-125 UMLS/C0205087 denotes late
T56 224-228 UMLS/C0205087 denotes late
T57 290-296 UMLS/C1550457 denotes normal
T59 30-33 UMLS/C1414151 denotes DRG
T60 404-407 UMLS/C1414151 denotes DRG
T61 589-592 UMLS/C1414151 denotes DRG
T62 190-199 UMLS/C0205384 denotes branching
T63 332-339 UMLS/C0359589 denotes provide
T65 692-694 UMLS/C0319022 denotes to
T66 290-296 UMLS/C1704701 denotes normal
T69 238-241 UMLS/C0812380 denotes ETS
T70 386-389 UMLS/C0812380 denotes ETS
T71 695-698 UMLS/C0812380 denotes ETS
T72 35-42 UMLS/C0445254 denotes sensory
T73 340-347 UMLS/C0314603 denotes genetic
T74 619-627 UMLS/C2362314 denotes temporal
T76 30-33 UMLS/C1537672 denotes DRG
T77 404-407 UMLS/C1537672 denotes DRG
T78 589-592 UMLS/C1537672 denotes DRG
T79 290-296 UMLS/C1873497 denotes normal
T80 733-743 UMLS/C1705294 denotes sequential
T81 126-133 UMLS/C1879746 denotes aspects
T82 744-749 UMLS/C0454366 denotes steps
T83 112-120 UMLS/C1547100 denotes controls
T84 472-480 UMLS/C1705314 denotes terminal
T85 472-480 UMLS/C1705315 denotes terminal
T86 229-234 UMLS/C0332162 denotes onset
T88 137-161 UMLS/C1518294 denotes neuronal differentiation
T89 229-234 UMLS/C1299997 denotes onset
T90 190-199 UMLS/C1706131 denotes branching
T92 516-529 UMLS/C0439857 denotes dependence on
T93 654-657 UMLS/C0006823 denotes can
T95 682-691 UMLS/C1704632 denotes responses
T96 744-749 UMLS/C1705117 denotes steps
T97 575-583 UMLS/C1444656 denotes indicate
T99 720-729 UMLS/C0037083 denotes signaling
T100 54-67 UMLS/C0026609 denotes motor neurons
T103 699-719 UMLS/C0040648 denotes transcription factor
T104 190-199 UMLS/C1253959 denotes branching
T106 744-749 UMLS/C1704379 denotes steps
T108 682-691 UMLS/C1706817 denotes responses
T109 654-657 UMLS/C0344312 denotes can
T110 8-28 UMLS/C1761610 denotes dorsal root ganglion
T111 101-111 UMLS/C0017262 denotes expression
T112 242-257 UMLS/C0017262 denotes gene expression
T113 390-400 UMLS/C0017262 denotes expression
T114 274-285 UMLS/C1514873 denotes requirement
T115 112-120 UMLS/C0243148 denotes controls
T116 290-296 UMLS/C0439166 denotes normal
T117 121-125 UMLS/C1279941 denotes late
T118 224-228 UMLS/C1279941 denotes late
T119 744-749 UMLS/C1261552 denotes steps
T120 375-385 UMLS/C1279930 denotes precocious
T121 78-85 UMLS/C2348040 denotes derived
T122 112-120 UMLS/C0009932 denotes controls
T123 264-273 UMLS/C0205224 denotes essential
T124 552-560 UMLS/C1883357 denotes Together
T125 126-133 UMLS/C1547011 denotes aspects
T128 238-241 UMLS/C1705691 denotes ETS
T129 386-389 UMLS/C1705691 denotes ETS
T130 695-698 UMLS/C1705691 denotes ETS
T131 440-451 UMLS/C0348018 denotes projections
T132 126-133 UMLS/C0700364 denotes aspects
T133 177-185 UMLS/C1269955 denotes invasion
T134 290-296 UMLS/C2347086 denotes normal
T135 71-77 UMLS/C1521840 denotes target
T136 170-176 UMLS/C1521840 denotes target
T137 190-199 UMLS/C2700383 denotes branching
T138 661-669 UMLS/C0443289 denotes revealed
T139 190-199 UMLS/C2700384 denotes branching
T140 47-53 UMLS/C0521329 denotes spinal
T142 720-729 UMLS/C1710082 denotes signaling
T144 628-641 UMLS/C0678723 denotes developmental
T146 71-77 UMLS/C0599894 denotes target
T147 170-176 UMLS/C0599894 denotes target
T148 753-761 UMLS/C0521390 denotes neuronal
T149 112-120 UMLS/C0332298 denotes controls
T150 177-185 UMLS/C2699153 denotes invasion
T151 440-451 UMLS/C0033363 denotes projections
T152 543-550 UMLS/C0344211 denotes support
T153 78-85 UMLS/C1711343 denotes derived
T154 305-327 UMLS/C1159970 denotes neuron differentiation
T155 733-743 UMLS/C1548958 denotes sequential
T156 543-550 UMLS/C1317973 denotes support
T157 78-85 UMLS/C1441547 denotes derived
T158 457-468 UMLS/C1706701 denotes acquisition
T159 101-111 UMLS/C0185117 denotes expression
T160 390-400 UMLS/C0185117 denotes expression
T162 628-641 UMLS/C0458003 denotes developmental
T163 190-199 UMLS/C1881507 denotes branching
T164 290-296 UMLS/C0205307 denotes normal
T167 238-241 UMLS/C0813971 denotes ETS
T168 386-389 UMLS/C0813971 denotes ETS
T169 695-698 UMLS/C0813971 denotes ETS
T170 566-574 UMLS/C2607943 denotes findings
T171 297-311 UMLS/C0034837 denotes sensory neuron
T172 408-423 UMLS/C0034837 denotes sensory neurons
T173 593-608 UMLS/C0034837 denotes sensory neurons
T174 481-504 UMLS/C0003324 denotes differentiation markers
T175 440-451 UMLS/C0016538 denotes projections
T176 8-28 UMLS/C0017070 denotes dorsal root ganglion
T177 619-627 UMLS/C0442043 denotes temporal
T179 30-33 UMLS/C0011928 denotes DRG
T180 404-407 UMLS/C0011928 denotes DRG
T181 589-592 UMLS/C0011928 denotes DRG
T182 112-120 UMLS/C2587213 denotes controls
T183 297-311 UMLS/C0027883 denotes sensory neuron
T184 408-423 UMLS/C0027883 denotes sensory neurons
T185 593-608 UMLS/C0027883 denotes sensory neurons

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T190 8-28 UBERON:0000044 denotes dorsal root ganglion
T191 8-28 _FRAGMENT denotes dorsal root ganglion
T192 35-42 _FRAGMENT denotes sensory
T193 60-67 CL:1001451 denotes neurons
T194 30-33 UBERON:0000044 denotes DRG
T195 30-33 _FRAGMENT denotes DRG
T196 47-53 UBERON:0001130 denotes spinal
T197 47-67 CL:0011001 denotes spinal motor neurons
T198 101-111 GO:0010467 denotes expression
T199 112-120 GO:0065007 denotes controls
T200 137-145 CL:0000540 denotes neuronal
T201 242-246 SO:0000704 denotes gene
T202 242-257 GO:0010467 denotes gene expression
T203 297-311 CL:0000101 denotes sensory neuron
T204 340-347 SO:0000704 denotes genetic
T205 364-369 NCBITaxon:10088 denotes mouse
T206 390-400 GO:0010467 denotes expression
T207 404-407 UBERON:0000044 denotes DRG
T208 404-423 CL:1001451 denotes DRG sensory neurons
T209 433-451 GO:0030424 denotes axonal projections
T210 589-592 UBERON:0000044 denotes DRG
T211 589-608 CL:1001451 denotes DRG sensory neurons
T212 753-761 CL:0000540 denotes neuronal
T213 753-772 GO:0042551 denotes neuronal maturation
R2 T192 T195 _lexicallyChainedTo sensory,DRG
R3 T193 T192 _lexicallyChainedTo neurons,sensory
R1 T192 T191 _lexicallyChainedTo sensory,dorsal root ganglion