PMC:1084331 / 18391-18855 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1084331","sourcedb":"PMC","sourceid":"1084331","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1084331","text":"To begin to address the cellular and molecular mechanisms involved in the distinct biological actions of EWS-Pea3 at different developmental stages, we first turned to in vitro culture experiments. These experiments permit assessment of whether precocious ETS transcription factor signaling influences neuronal survival and in vitro neurite outgrowth of DRG neurons, two parameters prominently influenced by target-derived neurotrophic factors and their receptors.","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T6718","span":{"begin":245,"end":255},"obj":"JJ"},{"id":"T6677","span":{"begin":0,"end":2},"obj":"TO"},{"id":"T6678","span":{"begin":3,"end":8},"obj":"VB"},{"id":"T6679","span":{"begin":158,"end":164},"obj":"VBD"},{"id":"T6680","span":{"begin":9,"end":11},"obj":"TO"},{"id":"T6681","span":{"begin":12,"end":19},"obj":"VB"},{"id":"T6682","span":{"begin":20,"end":23},"obj":"DT"},{"id":"T6683","span":{"begin":47,"end":57},"obj":"NNS"},{"id":"T6684","span":{"begin":24,"end":32},"obj":"JJ"},{"id":"T6685","span":{"begin":33,"end":36},"obj":"CC"},{"id":"T6686","span":{"begin":37,"end":46},"obj":"JJ"},{"id":"T6687","span":{"begin":58,"end":66},"obj":"VBN"},{"id":"T6688","span":{"begin":67,"end":69},"obj":"IN"},{"id":"T6689","span":{"begin":70,"end":73},"obj":"DT"},{"id":"T6690","span":{"begin":94,"end":101},"obj":"NNS"},{"id":"T6691","span":{"begin":74,"end":82},"obj":"JJ"},{"id":"T6692","span":{"begin":83,"end":93},"obj":"JJ"},{"id":"T6693","span":{"begin":102,"end":104},"obj":"IN"},{"id":"T6694","span":{"begin":105,"end":108},"obj":"NN"},{"id":"T6695","span":{"begin":109,"end":113},"obj":"NN"},{"id":"T6696","span":{"begin":108,"end":109},"obj":"HYPH"},{"id":"T6697","span":{"begin":114,"end":116},"obj":"IN"},{"id":"T6698","span":{"begin":117,"end":126},"obj":"JJ"},{"id":"T6699","span":{"begin":141,"end":147},"obj":"NNS"},{"id":"T6700","span":{"begin":127,"end":140},"obj":"JJ"},{"id":"T6701","span":{"begin":147,"end":149},"obj":","},{"id":"T6702","span":{"begin":149,"end":151},"obj":"PRP"},{"id":"T6703","span":{"begin":152,"end":157},"obj":"RB"},{"id":"T6704","span":{"begin":165,"end":167},"obj":"IN"},{"id":"T6705","span":{"begin":168,"end":170},"obj":"FW"},{"id":"T6706","span":{"begin":171,"end":176},"obj":"FW"},{"id":"T6707","span":{"begin":185,"end":196},"obj":"NNS"},{"id":"T6708","span":{"begin":177,"end":184},"obj":"NN"},{"id":"T6709","span":{"begin":196,"end":197},"obj":"."},{"id":"T6710","span":{"begin":197,"end":464},"obj":"sentence"},{"id":"T6711","span":{"begin":198,"end":203},"obj":"DT"},{"id":"T6712","span":{"begin":204,"end":215},"obj":"NNS"},{"id":"T6713","span":{"begin":216,"end":222},"obj":"VBP"},{"id":"T6714","span":{"begin":223,"end":233},"obj":"NN"},{"id":"T6715","span":{"begin":234,"end":236},"obj":"IN"},{"id":"T6716","span":{"begin":237,"end":244},"obj":"IN"},{"id":"T6717","span":{"begin":291,"end":301},"obj":"VBZ"},{"id":"T6719","span":{"begin":281,"end":290},"obj":"NN"},{"id":"T6720","span":{"begin":256,"end":259},"obj":"NN"},{"id":"T6721","span":{"begin":260,"end":273},"obj":"NN"},{"id":"T6722","span":{"begin":274,"end":280},"obj":"NN"},{"id":"T6723","span":{"begin":302,"end":310},"obj":"JJ"},{"id":"T6724","span":{"begin":311,"end":319},"obj":"NN"},{"id":"T6725","span":{"begin":320,"end":323},"obj":"CC"},{"id":"T6726","span":{"begin":324,"end":326},"obj":"FW"},{"id":"T6727","span":{"begin":327,"end":332},"obj":"FW"},{"id":"T6728","span":{"begin":341,"end":350},"obj":"NN"},{"id":"T6729","span":{"begin":333,"end":340},"obj":"NN"},{"id":"T6730","span":{"begin":351,"end":353},"obj":"IN"},{"id":"T6731","span":{"begin":354,"end":357},"obj":"NN"},{"id":"T6732","span":{"begin":358,"end":365},"obj":"NNS"},{"id":"T6733","span":{"begin":365,"end":367},"obj":","},{"id":"T6734","span":{"begin":367,"end":370},"obj":"CD"},{"id":"T6735","span":{"begin":371,"end":381},"obj":"NNS"},{"id":"T6736","span":{"begin":382,"end":393},"obj":"RB"},{"id":"T6737","span":{"begin":394,"end":404},"obj":"VBN"},{"id":"T6738","span":{"begin":405,"end":407},"obj":"IN"},{"id":"T6739","span":{"begin":408,"end":414},"obj":"NN"},{"id":"T6740","span":{"begin":415,"end":422},"obj":"VBN"},{"id":"T6741","span":{"begin":414,"end":415},"obj":"HYPH"},{"id":"T6742","span":{"begin":436,"end":443},"obj":"NNS"},{"id":"T6743","span":{"begin":423,"end":435},"obj":"JJ"},{"id":"T6744","span":{"begin":444,"end":447},"obj":"CC"},{"id":"T6745","span":{"begin":448,"end":453},"obj":"PRP$"},{"id":"T6746","span":{"begin":454,"end":463},"obj":"NNS"},{"id":"T6747","span":{"begin":463,"end":464},"obj":"."}],"relations":[{"id":"R2463","pred":"aux","subj":"T6677","obj":"T6678"},{"id":"R2464","pred":"advcl","subj":"T6678","obj":"T6679"},{"id":"R2465","pred":"aux","subj":"T6680","obj":"T6681"},{"id":"R2466","pred":"xcomp","subj":"T6681","obj":"T6678"},{"id":"R2467","pred":"det","subj":"T6682","obj":"T6683"},{"id":"R2468","pred":"dobj","subj":"T6683","obj":"T6681"},{"id":"R2469","pred":"amod","subj":"T6684","obj":"T6683"},{"id":"R2470","pred":"cc","subj":"T6685","obj":"T6684"},{"id":"R2471","pred":"conj","subj":"T6686","obj":"T6684"},{"id":"R2472","pred":"acl","subj":"T6687","obj":"T6683"},{"id":"R2473","pred":"prep","subj":"T6688","obj":"T6687"},{"id":"R2474","pred":"det","subj":"T6689","obj":"T6690"},{"id":"R2475","pred":"pobj","subj":"T6690","obj":"T6688"},{"id":"R2476","pred":"amod","subj":"T6691","obj":"T6690"},{"id":"R2477","pred":"amod","subj":"T6692","obj":"T6690"},{"id":"R2478","pred":"prep","subj":"T6693","obj":"T6690"},{"id":"R2479","pred":"compound","subj":"T6694","obj":"T6695"},{"id":"R2480","pred":"pobj","subj":"T6695","obj":"T6693"},{"id":"R2481","pred":"punct","subj":"T6696","obj":"T6695"},{"id":"R2482","pred":"prep","subj":"T6697","obj":"T6687"},{"id":"R2483","pred":"amod","subj":"T6698","obj":"T6699"},{"id":"R2484","pred":"pobj","subj":"T6699","obj":"T6697"},{"id":"R2485","pred":"amod","subj":"T6700","obj":"T6699"},{"id":"R2486","pred":"punct","subj":"T6701","obj":"T6679"},{"id":"R2487","pred":"nsubj","subj":"T6702","obj":"T6679"},{"id":"R2488","pred":"advmod","subj":"T6703","obj":"T6679"},{"id":"R2489","pred":"prep","subj":"T6704","obj":"T6679"},{"id":"R2490","pred":"advmod","subj":"T6705","obj":"T6706"},{"id":"R2491","pred":"amod","subj":"T6706","obj":"T6707"},{"id":"R2492","pred":"pobj","subj":"T6707","obj":"T6704"},{"id":"R2493","pred":"compound","subj":"T6708","obj":"T6707"},{"id":"R2494","pred":"punct","subj":"T6709","obj":"T6679"},{"id":"R2495","pred":"det","subj":"T6711","obj":"T6712"},{"id":"R2496","pred":"nsubj","subj":"T6712","obj":"T6713"},{"id":"R2497","pred":"dobj","subj":"T6714","obj":"T6713"},{"id":"R2498","pred":"prep","subj":"T6715","obj":"T6714"},{"id":"R2499","pred":"mark","subj":"T6716","obj":"T6717"},{"id":"R2500","pred":"pcomp","subj":"T6717","obj":"T6715"},{"id":"R2501","pred":"amod","subj":"T6718","obj":"T6719"},{"id":"R2502","pred":"nsubj","subj":"T6719","obj":"T6717"},{"id":"R2503","pred":"compound","subj":"T6720","obj":"T6719"},{"id":"R2504","pred":"compound","subj":"T6721","obj":"T6722"},{"id":"R2505","pred":"compound","subj":"T6722","obj":"T6719"},{"id":"R2506","pred":"amod","subj":"T6723","obj":"T6724"},{"id":"R2507","pred":"dobj","subj":"T6724","obj":"T6717"},{"id":"R2508","pred":"cc","subj":"T6725","obj":"T6724"},{"id":"R2509","pred":"nmod","subj":"T6726","obj":"T6727"},{"id":"R2510","pred":"nmod","subj":"T6727","obj":"T6728"},{"id":"R2511","pred":"conj","subj":"T6728","obj":"T6724"},{"id":"R2512","pred":"compound","subj":"T6729","obj":"T6728"},{"id":"R2513","pred":"prep","subj":"T6730","obj":"T6724"},{"id":"R2514","pred":"compound","subj":"T6731","obj":"T6732"},{"id":"R2515","pred":"pobj","subj":"T6732","obj":"T6730"},{"id":"R2516","pred":"punct","subj":"T6733","obj":"T6724"},{"id":"R2517","pred":"nummod","subj":"T6734","obj":"T6735"},{"id":"R2518","pred":"appos","subj":"T6735","obj":"T6724"},{"id":"R2519","pred":"advmod","subj":"T6736","obj":"T6737"},{"id":"R2520","pred":"acl","subj":"T6737","obj":"T6735"},{"id":"R2521","pred":"agent","subj":"T6738","obj":"T6737"},{"id":"R2522","pred":"npadvmod","subj":"T6739","obj":"T6740"},{"id":"R2523","pred":"amod","subj":"T6740","obj":"T6742"},{"id":"R2524","pred":"punct","subj":"T6741","obj":"T6740"},{"id":"R2525","pred":"pobj","subj":"T6742","obj":"T6738"},{"id":"R2526","pred":"amod","subj":"T6743","obj":"T6742"},{"id":"R2527","pred":"cc","subj":"T6744","obj":"T6742"},{"id":"R2528","pred":"poss","subj":"T6745","obj":"T6746"},{"id":"R2529","pred":"conj","subj":"T6746","obj":"T6742"},{"id":"R2530","pred":"punct","subj":"T6747","obj":"T6713"}],"attributes":[{"subj":"T6718","pred":"source","obj":"craft-sa-dev"},{"subj":"T6677","pred":"source","obj":"craft-sa-dev"},{"subj":"T6678","pred":"source","obj":"craft-sa-dev"},{"subj":"T6679","pred":"source","obj":"craft-sa-dev"},{"subj":"T6680","pred":"source","obj":"craft-sa-dev"},{"subj":"T6681","pred":"source","obj":"craft-sa-dev"},{"subj":"T6682","pred":"source","obj":"craft-sa-dev"},{"subj":"T6683","pred":"source","obj":"craft-sa-dev"},{"subj":"T6684","pred":"source","obj":"craft-sa-dev"},{"subj":"T6685","pred":"source","obj":"craft-sa-dev"},{"subj":"T6686","pred":"source","obj":"craft-sa-dev"},{"subj":"T6687","pred":"source","obj":"craft-sa-dev"},{"subj":"T6688","pred":"source","obj":"craft-sa-dev"},{"subj":"T6689","pred":"source","obj":"craft-sa-dev"},{"subj":"T6690","pred":"source","obj":"craft-sa-dev"},{"subj":"T6691","pred":"source","obj":"craft-sa-dev"},{"subj":"T6692","pred":"source","obj":"craft-sa-dev"},{"subj":"T6693","pred":"source","obj":"craft-sa-dev"},{"subj":"T6694","pred":"source","obj":"craft-sa-dev"},{"subj":"T6695","pred":"source","obj":"craft-sa-dev"},{"subj":"T6696","pred":"source","obj":"craft-sa-dev"},{"subj":"T6697","pred":"source","obj":"craft-sa-dev"},{"subj":"T6698","pred":"source","obj":"craft-sa-dev"},{"subj":"T6699","pred":"source","obj":"craft-sa-dev"},{"subj":"T6700","pred":"source","obj":"craft-sa-dev"},{"subj":"T6701","pred":"source","obj":"craft-sa-dev"},{"subj":"T6702","pred":"source","obj":"craft-sa-dev"},{"subj":"T6703","pred":"source","obj":"craft-sa-dev"},{"subj":"T6704","pred":"source","obj":"craft-sa-dev"},{"subj":"T6705","pred":"source","obj":"craft-sa-dev"},{"subj":"T6706","pred":"source","obj":"craft-sa-dev"},{"subj":"T6707","pred":"source","obj":"craft-sa-dev"},{"subj":"T6708","pred":"source","obj":"craft-sa-dev"},{"subj":"T6709","pred":"source","obj":"craft-sa-dev"},{"subj":"T6710","pred":"source","obj":"craft-sa-dev"},{"subj":"T6711","pred":"source","obj":"craft-sa-dev"},{"subj":"T6712","pred":"source","obj":"craft-sa-dev"},{"subj":"T6713","pred":"source","obj":"craft-sa-dev"},{"subj":"T6714","pred":"source","obj":"craft-sa-dev"},{"subj":"T6715","pred":"source","obj":"craft-sa-dev"},{"subj":"T6716","pred":"source","obj":"craft-sa-dev"},{"subj":"T6717","pred":"source","obj":"craft-sa-dev"},{"subj":"T6719","pred":"source","obj":"craft-sa-dev"},{"subj":"T6720","pred":"source","obj":"craft-sa-dev"},{"subj":"T6721","pred":"source","obj":"craft-sa-dev"},{"subj":"T6722","pred":"source","obj":"craft-sa-dev"},{"subj":"T6723","pred":"source","obj":"craft-sa-dev"},{"subj":"T6724","pred":"source","obj":"craft-sa-dev"},{"subj":"T6725","pred":"source","obj":"craft-sa-dev"},{"subj":"T6726","pred":"source","obj":"craft-sa-dev"},{"subj":"T6727","pred":"source","obj":"craft-sa-dev"},{"subj":"T6728","pred":"source","obj":"craft-sa-dev"},{"subj":"T6729","pred":"source","obj":"craft-sa-dev"},{"subj":"T6730","pred":"source","obj":"craft-sa-dev"},{"subj":"T6731","pred":"source","obj":"craft-sa-dev"},{"subj":"T6732","pred":"source","obj":"craft-sa-dev"},{"subj":"T6733","pred":"source","obj":"craft-sa-dev"},{"subj":"T6734","pred":"source","obj":"craft-sa-dev"},{"subj":"T6735","pred":"source","obj":"craft-sa-dev"},{"subj":"T6736","pred":"source","obj":"craft-sa-dev"},{"subj":"T6737","pred":"source","obj":"craft-sa-dev"},{"subj":"T6738","pred":"source","obj":"craft-sa-dev"},{"subj":"T6739","pred":"source","obj":"craft-sa-dev"},{"subj":"T6740","pred":"source","obj":"craft-sa-dev"},{"subj":"T6741","pred":"source","obj":"craft-sa-dev"},{"subj":"T6742","pred":"source","obj":"craft-sa-dev"},{"subj":"T6743","pred":"source","obj":"craft-sa-dev"},{"subj":"T6744","pred":"source","obj":"craft-sa-dev"},{"subj":"T6745","pred":"source","obj":"craft-sa-dev"},{"subj":"T6746","pred":"source","obj":"craft-sa-dev"},{"subj":"T6747","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T6330","span":{"begin":24,"end":32},"obj":"CL_GO_EXT:cell"},{"id":"T6331","span":{"begin":37,"end":46},"obj":"CHEBI_EXT:polyatomic_entity_or_group"},{"id":"T6332","span":{"begin":83,"end":93},"obj":"CHEBI_GO_EXT:biological_process_or_quality_or_role"},{"id":"T6333","span":{"begin":105,"end":108},"obj":"PR_EXT:000007243"},{"id":"T6334","span":{"begin":109,"end":113},"obj":"PR_EXT:000007227"},{"id":"T6335","span":{"begin":260,"end":273},"obj":"GO_EXT:transcription"},{"id":"T6336","span":{"begin":260,"end":280},"obj":"GO_EXT:transcription_factor"},{"id":"T6337","span":{"begin":281,"end":290},"obj":"GO_EXT:cell_communication_or_signaling_or_signal_transduction"},{"id":"T6338","span":{"begin":302,"end":310},"obj":"CL:0000540"},{"id":"T6339","span":{"begin":333,"end":340},"obj":"GO:0043005"},{"id":"T6340","span":{"begin":354,"end":357},"obj":"UBERON:0000044"},{"id":"T6341","span":{"begin":358,"end":365},"obj":"CL:0000540"},{"id":"T6342","span":{"begin":423,"end":435},"obj":"GO_EXT:neuron_development_or_generation"},{"id":"T6343","span":{"begin":454,"end":463},"obj":"GO_EXT:0004872"}],"attributes":[{"subj":"T6330","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6331","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6332","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6333","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6334","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6335","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6336","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6337","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6338","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6339","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6340","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6341","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6342","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T6343","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T6085","span":{"begin":105,"end":108},"obj":"PR:000007243"},{"id":"T6086","span":{"begin":109,"end":113},"obj":"PR:000007227"},{"id":"T6087","span":{"begin":302,"end":310},"obj":"CL:0000540"},{"id":"T6088","span":{"begin":333,"end":340},"obj":"GO:0043005"},{"id":"T6089","span":{"begin":354,"end":357},"obj":"UBERON:0000044"},{"id":"T6090","span":{"begin":358,"end":365},"obj":"CL:0000540"}],"attributes":[{"subj":"T6085","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T6086","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T6087","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T6088","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T6089","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T6090","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#93c5ec","default":true},{"id":"craft-ca-core-ex-dev","color":"#dfec93"},{"id":"craft-ca-core-dev","color":"#df93ec"}]}]}}