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PMC:1084331 / 182-1012 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T281 26-33 VBN denotes induced
T282 0-2 IN denotes of
T283 3-6 DT denotes the
T284 12-21 NN denotes subfamily
T285 7-11 NN denotes Pea3
T286 22-25 VBP denotes are
T287 34-36 IN denotes in
T288 37-51 NNS denotes subpopulations
T289 52-54 IN denotes of
T290 55-61 JJ denotes dorsal
T291 67-75 NN denotes ganglion
T292 62-66 NN denotes root
T293 107-114 NNS denotes neurons
T294 76-77 -LRB- denotes (
T295 77-80 NN denotes DRG
T296 80-81 -RRB- denotes )
T297 82-89 JJ denotes sensory
T298 90-93 CC denotes and
T299 94-100 JJ denotes spinal
T300 101-106 NN denotes motor
T301 115-117 IN denotes by
T302 118-124 NN denotes target
T303 125-132 VBN denotes derived
T304 124-125 HYPH denotes -
T305 133-140 NNS denotes factors
T306 140-141 . denotes .
T307 141-247 sentence denotes Their expression controls late aspects of neuronal differentiation such as target invasion and branching.
T308 142-147 PRP$ denotes Their
T309 148-158 NN denotes expression
T310 159-167 VBZ denotes controls
T311 168-172 JJ denotes late
T312 173-180 NNS denotes aspects
T313 181-183 IN denotes of
T314 184-192 JJ denotes neuronal
T315 193-208 NN denotes differentiation
T316 209-213 JJ denotes such
T317 214-216 IN denotes as
T318 217-223 NN denotes target
T319 224-232 NN denotes invasion
T320 233-236 CC denotes and
T321 237-246 NN denotes branching
T322 246-247 . denotes .
T323 247-375 sentence denotes Here, we show that the late onset of ETS gene expression is an essential requirement for normal sensory neuron differentiation.
T324 248-252 RB denotes Here
T325 257-261 VBP denotes show
T326 252-254 , denotes ,
T327 254-256 PRP denotes we
T328 262-266 IN denotes that
T329 305-307 VBZ denotes is
T330 267-270 DT denotes the
T331 276-281 NN denotes onset
T332 271-275 JJ denotes late
T333 282-284 IN denotes of
T334 285-288 NN denotes ETS
T335 289-293 NN denotes gene
T336 294-304 NN denotes expression
T337 308-310 DT denotes an
T338 321-332 NN denotes requirement
T339 311-320 JJ denotes essential
T340 333-336 IN denotes for
T341 337-343 JJ denotes normal
T342 359-374 NN denotes differentiation
T343 344-351 JJ denotes sensory
T344 352-358 NN denotes neuron
T345 374-375 . denotes .
T346 375-598 sentence denotes We provide genetic evidence in the mouse that precocious ETS expression in DRG sensory neurons perturbs axonal projections, the acquisition of terminal differentiation markers, and their dependence on neurotrophic support.
T347 376-378 PRP denotes We
T348 379-386 VBP denotes provide
T349 387-394 JJ denotes genetic
T350 395-403 NN denotes evidence
T351 404-406 IN denotes in
T352 407-410 DT denotes the
T353 411-416 NN denotes mouse
T354 417-421 IN denotes that
T355 471-479 VBZ denotes perturbs
T356 422-432 JJ denotes precocious
T357 437-447 NN denotes expression
T358 433-436 NN denotes ETS
T359 448-450 IN denotes in
T360 451-454 NN denotes DRG
T361 463-470 NNS denotes neurons
T362 455-462 JJ denotes sensory
T363 480-486 JJ denotes axonal
T364 487-498 NNS denotes projections
T365 498-500 , denotes ,
T366 500-503 DT denotes the
T367 504-515 NN denotes acquisition
T368 516-518 IN denotes of
T369 519-527 JJ denotes terminal
T370 544-551 NNS denotes markers
T371 528-543 NN denotes differentiation
T372 551-553 , denotes ,
T373 553-556 CC denotes and
T374 557-562 PRP$ denotes their
T375 563-573 NN denotes dependence
T376 574-576 IN denotes on
T377 577-589 JJ denotes neurotrophic
T378 590-597 NN denotes support
T379 597-598 . denotes .
T380 598-820 sentence denotes Together, our findings indicate that DRG sensory neurons exhibit a temporal developmental switch that can be revealed by distinct responses to ETS transcription factor signaling at sequential steps of neuronal maturation.
T381 599-607 RB denotes Together
T382 622-630 VBP denotes indicate
T383 607-609 , denotes ,
T384 609-612 PRP$ denotes our
T385 613-621 NNS denotes findings
T386 631-635 IN denotes that
T387 656-663 VBP denotes exhibit
T388 636-639 NN denotes DRG
T389 648-655 NNS denotes neurons
T390 640-647 JJ denotes sensory
T391 664-665 DT denotes a
T392 689-695 NN denotes switch
T393 666-674 JJ denotes temporal
T394 675-688 JJ denotes developmental
T395 696-700 WDT denotes that
T396 708-716 VBN denotes revealed
T397 701-704 MD denotes can
T398 705-707 VB denotes be
T399 717-719 IN denotes by
T400 720-728 JJ denotes distinct
T401 729-738 NNS denotes responses
T402 739-741 IN denotes to
T403 742-745 NN denotes ETS
T404 767-776 NN denotes signaling
T405 746-759 NN denotes transcription
T406 760-766 NN denotes factor
T407 777-779 IN denotes at
T408 780-790 JJ denotes sequential
T409 791-796 NNS denotes steps
T410 797-799 IN denotes of
T411 800-808 JJ denotes neuronal
T412 809-819 NN denotes maturation
T413 819-820 . denotes .
R91 T356 T357 amod precocious,expression
R24 T283 T284 det the,subfamily
R25 T284 T282 pobj subfamily,of
R26 T285 T284 compound Pea3,subfamily
R27 T286 T281 auxpass are,induced
R28 T287 T281 prep in,induced
R29 T288 T287 pobj subpopulations,in
R30 T289 T288 prep of,subpopulations
R31 T290 T291 amod dorsal,ganglion
R32 T291 T293 nmod ganglion,neurons
R33 T292 T291 nmod root,ganglion
R34 T293 T289 pobj neurons,of
R35 T294 T291 punct (,ganglion
R36 T295 T291 appos DRG,ganglion
R37 T296 T291 punct ),ganglion
R38 T297 T293 amod sensory,neurons
R39 T298 T297 cc and,sensory
R40 T299 T300 amod spinal,motor
R41 T300 T297 conj motor,sensory
R42 T301 T281 agent by,induced
R43 T302 T303 npadvmod target,derived
R44 T303 T305 amod derived,factors
R45 T304 T303 punct -,derived
R46 T305 T301 pobj factors,by
R47 T306 T281 punct .,induced
R48 T308 T309 poss Their,expression
R49 T309 T310 nsubj expression,controls
R50 T311 T312 amod late,aspects
R51 T312 T310 dobj aspects,controls
R52 T313 T312 prep of,aspects
R53 T314 T315 amod neuronal,differentiation
R54 T315 T313 pobj differentiation,of
R55 T316 T317 amod such,as
R56 T317 T312 prep as,aspects
R57 T318 T319 compound target,invasion
R58 T319 T317 pobj invasion,as
R59 T320 T319 cc and,invasion
R60 T321 T319 conj branching,invasion
R61 T322 T310 punct .,controls
R62 T324 T325 advmod Here,show
R63 T326 T325 punct ", ",show
R64 T327 T325 nsubj we,show
R65 T328 T329 mark that,is
R66 T329 T325 ccomp is,show
R67 T330 T331 det the,onset
R68 T331 T329 nsubj onset,is
R69 T332 T331 amod late,onset
R70 T333 T331 prep of,onset
R71 T334 T335 compound ETS,gene
R72 T335 T336 compound gene,expression
R73 T336 T333 pobj expression,of
R74 T337 T338 det an,requirement
R75 T338 T329 attr requirement,is
R76 T339 T338 amod essential,requirement
R77 T340 T338 prep for,requirement
R78 T341 T342 amod normal,differentiation
R79 T342 T340 pobj differentiation,for
R80 T343 T344 amod sensory,neuron
R81 T344 T342 compound neuron,differentiation
R82 T345 T325 punct .,show
R83 T347 T348 nsubj We,provide
R84 T349 T350 amod genetic,evidence
R85 T350 T348 dobj evidence,provide
R86 T351 T348 prep in,provide
R87 T352 T353 det the,mouse
R88 T353 T351 pobj mouse,in
R89 T354 T355 mark that,perturbs
R90 T355 T348 ccomp perturbs,provide
R92 T357 T355 nsubj expression,perturbs
R93 T358 T357 compound ETS,expression
R94 T359 T357 prep in,expression
R95 T360 T361 nmod DRG,neurons
R96 T361 T359 pobj neurons,in
R97 T362 T361 amod sensory,neurons
R98 T363 T364 amod axonal,projections
R99 T364 T355 dobj projections,perturbs
R100 T365 T364 punct ", ",projections
R101 T366 T367 det the,acquisition
R102 T367 T364 conj acquisition,projections
R103 T368 T367 prep of,acquisition
R104 T369 T370 amod terminal,markers
R105 T370 T368 pobj markers,of
R106 T371 T370 compound differentiation,markers
R107 T372 T367 punct ", ",acquisition
R108 T373 T367 cc and,acquisition
R109 T374 T375 poss their,dependence
R110 T375 T367 conj dependence,acquisition
R111 T376 T375 prep on,dependence
R112 T377 T378 amod neurotrophic,support
R113 T378 T376 pobj support,on
R114 T379 T348 punct .,provide
R115 T381 T382 advmod Together,indicate
R116 T383 T382 punct ", ",indicate
R117 T384 T385 poss our,findings
R118 T385 T382 nsubj findings,indicate
R119 T386 T387 mark that,exhibit
R120 T387 T382 ccomp exhibit,indicate
R121 T388 T389 nmod DRG,neurons
R122 T389 T387 nsubj neurons,exhibit
R123 T390 T389 amod sensory,neurons
R124 T391 T392 det a,switch
R125 T392 T387 dobj switch,exhibit
R126 T393 T392 amod temporal,switch
R127 T394 T392 amod developmental,switch
R128 T395 T396 dep that,revealed
R129 T396 T392 relcl revealed,switch
R130 T397 T396 aux can,revealed
R131 T398 T396 auxpass be,revealed
R132 T399 T396 agent by,revealed
R133 T400 T401 amod distinct,responses
R134 T401 T399 pobj responses,by
R135 T402 T401 prep to,responses
R136 T403 T404 compound ETS,signaling
R137 T404 T402 pobj signaling,to
R138 T405 T406 compound transcription,factor
R139 T406 T404 compound factor,signaling
R140 T407 T401 prep at,responses
R141 T408 T409 amod sequential,steps
R142 T409 T407 pobj steps,at
R143 T410 T409 prep of,steps
R144 T411 T412 amod neuronal,maturation
R145 T412 T410 pobj maturation,of
R146 T413 T382 punct .,indicate

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T222 7-11 PR_EXT:000007227 denotes Pea3
T223 55-75 UBERON:0000044 denotes dorsal root ganglion
T224 55-75 _FRAGMENT denotes dorsal root ganglion
T225 82-89 _FRAGMENT denotes sensory
T226 107-114 CL:1001451 denotes neurons
T227 77-80 UBERON:0000044 denotes DRG
T228 77-80 _FRAGMENT denotes DRG
T229 82-89 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T230 94-100 UBERON:0001130 denotes spinal
T231 94-114 CL:0011001 denotes spinal motor neurons
T232 101-106 GO_EXT:biological_movement_or_translocation_process denotes motor
T233 148-158 GO:0010467 denotes expression
T234 159-167 GO:0065007 denotes controls
T235 184-192 CL:0000540 denotes neuronal
T236 193-208 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T237 289-293 SO_EXT:0000704 denotes gene
T238 289-304 GO:0010467 denotes gene expression
T239 344-358 CL:0000101 denotes sensory neuron
T240 359-374 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T241 387-394 SO_EXT:0000704 denotes genetic
T242 411-416 NCBITaxon:10088 denotes mouse
T243 437-447 GO:0010467 denotes expression
T244 451-454 UBERON:0000044 denotes DRG
T245 451-470 CL:1001451 denotes DRG sensory neurons
T246 455-462 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T247 480-498 GO:0030424 denotes axonal projections
T248 528-543 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T249 544-551 CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag denotes markers
T250 577-589 GO_EXT:neuron_development_or_generation denotes neurotrophic
T251 636-639 UBERON:0000044 denotes DRG
T252 636-655 CL:1001451 denotes DRG sensory neurons
T253 640-647 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T254 729-738 GO_EXT:reaction_or_response denotes responses
T255 746-759 GO_EXT:transcription denotes transcription
T256 746-766 GO_EXT:transcription_factor denotes transcription factor
T257 767-776 GO_EXT:cell_communication_or_signaling_or_signal_transduction denotes signaling
T258 800-808 CL:0000540 denotes neuronal
T259 800-819 GO:0042551 denotes neuronal maturation
R4 T225 T224 _lexicallyChainedTo sensory,dorsal root ganglion
R5 T225 T228 _lexicallyChainedTo sensory,DRG
R6 T226 T225 _lexicallyChainedTo neurons,sensory

biosemtest

Id Subject Object Predicate Lexical cue
T41 590-597 UMLS/C1521721 denotes support
T42 159-167 UMLS/C1882979 denotes controls
T43 159-167 UMLS/C1550141 denotes controls
T45 729-738 UMLS/C0871261 denotes responses
T47 689-695 UMLS/C1707719 denotes switch
T48 590-597 UMLS/C0183683 denotes support
T49 337-343 UMLS/C1551394 denotes normal
T50 666-674 UMLS/C0205374 denotes temporal
T51 519-527 UMLS/C0205088 denotes terminal
T52 656-663 UMLS/C0015272 denotes exhibit
T53 395-403 UMLS/C0332120 denotes evidence
T54 809-819 UMLS/C1254042 denotes maturation
T55 168-172 UMLS/C0205087 denotes late
T56 271-275 UMLS/C0205087 denotes late
T57 337-343 UMLS/C1550457 denotes normal
T59 77-80 UMLS/C1414151 denotes DRG
T60 451-454 UMLS/C1414151 denotes DRG
T61 636-639 UMLS/C1414151 denotes DRG
T62 237-246 UMLS/C0205384 denotes branching
T63 379-386 UMLS/C0359589 denotes provide
T65 739-741 UMLS/C0319022 denotes to
T66 337-343 UMLS/C1704701 denotes normal
T69 285-288 UMLS/C0812380 denotes ETS
T70 433-436 UMLS/C0812380 denotes ETS
T71 742-745 UMLS/C0812380 denotes ETS
T72 82-89 UMLS/C0445254 denotes sensory
T73 387-394 UMLS/C0314603 denotes genetic
T74 666-674 UMLS/C2362314 denotes temporal
T76 77-80 UMLS/C1537672 denotes DRG
T77 451-454 UMLS/C1537672 denotes DRG
T78 636-639 UMLS/C1537672 denotes DRG
T79 337-343 UMLS/C1873497 denotes normal
T80 780-790 UMLS/C1705294 denotes sequential
T81 173-180 UMLS/C1879746 denotes aspects
T82 791-796 UMLS/C0454366 denotes steps
T83 159-167 UMLS/C1547100 denotes controls
T84 519-527 UMLS/C1705314 denotes terminal
T85 519-527 UMLS/C1705315 denotes terminal
T86 276-281 UMLS/C0332162 denotes onset
T87 37-51 UMLS/C1257890 denotes subpopulations
T88 184-208 UMLS/C1518294 denotes neuronal differentiation
T89 276-281 UMLS/C1299997 denotes onset
T90 237-246 UMLS/C1706131 denotes branching
T91 12-21 UMLS/C1711207 denotes subfamily
T92 563-576 UMLS/C0439857 denotes dependence on
T93 701-704 UMLS/C0006823 denotes can
T95 729-738 UMLS/C1704632 denotes responses
T96 791-796 UMLS/C1705117 denotes steps
T97 622-630 UMLS/C1444656 denotes indicate
T99 767-776 UMLS/C0037083 denotes signaling
T100 101-114 UMLS/C0026609 denotes motor neurons
T103 746-766 UMLS/C0040648 denotes transcription factor
T104 237-246 UMLS/C1253959 denotes branching
T106 791-796 UMLS/C1704379 denotes steps
T108 729-738 UMLS/C1706817 denotes responses
T109 701-704 UMLS/C0344312 denotes can
T110 55-75 UMLS/C1761610 denotes dorsal root ganglion
T111 148-158 UMLS/C0017262 denotes expression
T112 289-304 UMLS/C0017262 denotes gene expression
T113 437-447 UMLS/C0017262 denotes expression
T114 321-332 UMLS/C1514873 denotes requirement
T115 159-167 UMLS/C0243148 denotes controls
T116 337-343 UMLS/C0439166 denotes normal
T117 168-172 UMLS/C1279941 denotes late
T118 271-275 UMLS/C1279941 denotes late
T119 791-796 UMLS/C1261552 denotes steps
T120 422-432 UMLS/C1279930 denotes precocious
T121 125-132 UMLS/C2348040 denotes derived
T122 159-167 UMLS/C0009932 denotes controls
T123 311-320 UMLS/C0205224 denotes essential
T124 599-607 UMLS/C1883357 denotes Together
T125 173-180 UMLS/C1547011 denotes aspects
T128 285-288 UMLS/C1705691 denotes ETS
T129 433-436 UMLS/C1705691 denotes ETS
T130 742-745 UMLS/C1705691 denotes ETS
T131 487-498 UMLS/C0348018 denotes projections
T132 173-180 UMLS/C0700364 denotes aspects
T133 224-232 UMLS/C1269955 denotes invasion
T134 337-343 UMLS/C2347086 denotes normal
T135 118-124 UMLS/C1521840 denotes target
T136 217-223 UMLS/C1521840 denotes target
T137 237-246 UMLS/C2700383 denotes branching
T138 708-716 UMLS/C0443289 denotes revealed
T139 237-246 UMLS/C2700384 denotes branching
T140 94-100 UMLS/C0521329 denotes spinal
T142 767-776 UMLS/C1710082 denotes signaling
T144 675-688 UMLS/C0678723 denotes developmental
T145 26-33 UMLS/C0205263 denotes induced
T146 118-124 UMLS/C0599894 denotes target
T147 217-223 UMLS/C0599894 denotes target
T148 800-808 UMLS/C0521390 denotes neuronal
T149 159-167 UMLS/C0332298 denotes controls
T150 224-232 UMLS/C2699153 denotes invasion
T151 487-498 UMLS/C0033363 denotes projections
T152 590-597 UMLS/C0344211 denotes support
T153 125-132 UMLS/C1711343 denotes derived
T154 352-374 UMLS/C1159970 denotes neuron differentiation
T155 780-790 UMLS/C1548958 denotes sequential
T156 590-597 UMLS/C1317973 denotes support
T157 125-132 UMLS/C1441547 denotes derived
T158 504-515 UMLS/C1706701 denotes acquisition
T159 148-158 UMLS/C0185117 denotes expression
T160 437-447 UMLS/C0185117 denotes expression
T162 675-688 UMLS/C0458003 denotes developmental
T163 237-246 UMLS/C1881507 denotes branching
T164 337-343 UMLS/C0205307 denotes normal
T167 285-288 UMLS/C0813971 denotes ETS
T168 433-436 UMLS/C0813971 denotes ETS
T169 742-745 UMLS/C0813971 denotes ETS
T170 613-621 UMLS/C2607943 denotes findings
T171 344-358 UMLS/C0034837 denotes sensory neuron
T172 455-470 UMLS/C0034837 denotes sensory neurons
T173 640-655 UMLS/C0034837 denotes sensory neurons
T174 528-551 UMLS/C0003324 denotes differentiation markers
T175 487-498 UMLS/C0016538 denotes projections
T176 55-75 UMLS/C0017070 denotes dorsal root ganglion
T177 666-674 UMLS/C0442043 denotes temporal
T179 77-80 UMLS/C0011928 denotes DRG
T180 451-454 UMLS/C0011928 denotes DRG
T181 636-639 UMLS/C0011928 denotes DRG
T182 159-167 UMLS/C2587213 denotes controls
T183 344-358 UMLS/C0027883 denotes sensory neuron
T184 455-470 UMLS/C0027883 denotes sensory neurons
T185 640-655 UMLS/C0027883 denotes sensory neurons

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T189 7-11 PR:000007227 denotes Pea3
T190 55-75 UBERON:0000044 denotes dorsal root ganglion
T191 55-75 _FRAGMENT denotes dorsal root ganglion
T192 82-89 _FRAGMENT denotes sensory
T193 107-114 CL:1001451 denotes neurons
T194 77-80 UBERON:0000044 denotes DRG
T195 77-80 _FRAGMENT denotes DRG
T196 94-100 UBERON:0001130 denotes spinal
T197 94-114 CL:0011001 denotes spinal motor neurons
T198 148-158 GO:0010467 denotes expression
T199 159-167 GO:0065007 denotes controls
T200 184-192 CL:0000540 denotes neuronal
T201 289-293 SO:0000704 denotes gene
T202 289-304 GO:0010467 denotes gene expression
T203 344-358 CL:0000101 denotes sensory neuron
T204 387-394 SO:0000704 denotes genetic
T205 411-416 NCBITaxon:10088 denotes mouse
T206 437-447 GO:0010467 denotes expression
T207 451-454 UBERON:0000044 denotes DRG
T208 451-470 CL:1001451 denotes DRG sensory neurons
T209 480-498 GO:0030424 denotes axonal projections
T210 636-639 UBERON:0000044 denotes DRG
T211 636-655 CL:1001451 denotes DRG sensory neurons
T212 800-808 CL:0000540 denotes neuronal
T213 800-819 GO:0042551 denotes neuronal maturation
R2 T192 T195 _lexicallyChainedTo sensory,DRG
R3 T193 T192 _lexicallyChainedTo neurons,sensory
R1 T192 T191 _lexicallyChainedTo sensory,dorsal root ganglion