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{"project":"NEUROSES","denotations":[{"id":"T309","span":{"begin":73,"end":80},"obj":"PATO_0000001"},{"id":"T313","span":{"begin":101,"end":109},"obj":"PATO_0001230"},{"id":"T315","span":{"begin":199,"end":204},"obj":"CHEBI_24433"}],"text":"Background\nSystems that are used by different organisations to grade the quality of evidence and the strength of recommendations vary. They have different strengths and weaknesses. The GRADE Working Group has developed an approach that addresses key shortcomings in these systems. The aim of this study was to pilot test and further develop the GRADE approach to grading evidence and recommendations."}