PMC:1079843 / 29362-30360 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/1079843","sourcedb":"PMC","sourceid":"1079843","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1079843","text":"Conclusion\nBipolar disorder is a complex genetic disorder with a spectrum of phenotype is associated with bipolar susceptibility genes. Since the subject assessment in this study was only by direct clinical interview according to the DSM-IV but not supported by any other standard tools like the SCID, it is worth noting the potential weakness of the study. The simple assessment procedure without dimensional measures of other psychopathological features also limits the possibility to detect association with particular attribute related to the disease. In summary, results from both single-locus and haplotype analyses did not support the role of TPH1 gene in BPD etiology. Furthermore, our data indicated significant LD within this 29 Kb interval of the TPH1 gene in Taiwanese population. 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