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PMC:1064895 / 27563-27838 JSONTXT

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test3

Id Subject Object Predicate Lexical cue
T17219 245-253 Entity denotes promoter
T17218 239-244 Protein denotes IL-17
T17217 215-222 Binding denotes binding
T17216 131-136 Protein denotes IL-17
T17215 115-127 Positive_regulation denotes upregulation
T17214 40-43 Protein denotes Akt
T17093 239-244 Protein denotes IL-17
T17092 131-136 Protein denotes IL-17
T17091 40-43 Protein denotes Akt
R9324 T17216 T17215 themeOf IL-17,upregulation
R9325 T17219 T17218 partOf promoter,IL-17
R9326 T17219 T17217 themeOf promoter,binding

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T20162 115-127 Positive_regulation denotes upregulation
T20106 239-244 Protein denotes IL-17
T20105 131-136 Protein denotes IL-17
T20104 40-43 Protein denotes Akt
R10636 T20105 T20162 themeOf IL-17,upregulation

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T21979 115-127 Positive_regulation denotes upregulation
T21978 197-205 Negative_regulation denotes blocking
T21930 239-244 Protein denotes IL-17
T21929 131-136 Protein denotes IL-17
T21928 40-43 Protein denotes Akt
R12051 T21929 T21979 themeOf IL-17,upregulation
R12052 T21930 T21978 themeOf IL-17,blocking

biosemtest

Id Subject Object Predicate Lexical cue
T18061 231-238 UMLS/C0243122 denotes in the
T18024 239-247 UMLS/C0439167 denotes IL-17 pr
T17826 239-247 UMLS/C1561536 denotes IL-17 pr
T17819 212-220 UMLS/C0332206 denotes κB bindi
T17807 199-211 UMLS/C0521115 denotes ocking of NF
T17793 231-238 UMLS/C1167622 denotes in the
T17781 255-260 UMLS/C1623218 denotes y PDT
T17780 146-151 UMLS/C1623218 denotes the
T17723 261-269 UMLS/C0086860 denotes and LY2
T17694 255-260 UMLS/C1825592 denotes y PDT
T17693 146-151 UMLS/C1825592 denotes the
T17669 5-12 UMLS/C0332268 denotes ata cle
T17553 18-22 UMLS/C1511726 denotes emon
T17542 90-95 UMLS/C0006823 denotes ortan
T18007 90-95 UMLS/C0344312 denotes ortan
T17985 49-53 UMLS/C1705325 denotes esul
T17963 179-190 UMLS/C1706386 denotes wing simult
T17916 49-53 UP/P42336 denotes esul
T17901 255-260 UMLS/C0384648 denotes y PDT
T17900 146-151 UMLS/C0384648 denotes the
T17514 231-238 UMLS/C1689898 denotes in the
T17508 239-247 UMLS/C0441655 denotes IL-17 pr
T17498 54-57 UP/Q8INB9 denotes ant
T17428 199-211 UMLS/C1548968 denotes ocking of NF
T17426 79-89 UMLS/C1879547 denotes d be an im
T17368 166-171 UMLS/C1527178 denotes perim
T17328 49-53 UMLS/C1368105 denotes esul
T17321 179-190 UMLS/C0681814 denotes wing simult
T17316 212-220 UMLS/C1706084 denotes κB bindi
T17643 49-53 UMLS/C1150481 denotes esul
T17585 130-142 UMLS/C0041904 denotes IL-17 in RA
T17300 212-220 UMLS/C1533157 denotes κB bindi
T17269 49-53 UMLS/C0285761 denotes esul
T17257 212-220 UMLS/C0028778 denotes κB bindi
T17255 212-220 UMLS/C0233660 denotes κB bindi
T17245 231-238 UMLS/C1145667 denotes in the
T17242 231-238 UMLS/C2349209 denotes in the
T17362 255-260 UMLS/C1522571 denotes y PDT
T17361 146-151 UMLS/C1522571 denotes the

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T19401 266-274 NN denotes LY294002
T19400 262-265 CC denotes and
T19395 235-238 DT denotes the
T19394 232-234 IN denotes in
T19393 223-231 NN denotes activity
T19392 215-222 NN denotes binding
T19391 209-214 NN denotes NF-κB
T19390 206-208 IN denotes of
T19389 197-205 NN denotes blocking
T19388 184-196 JJ denotes simultaneous
T19387 176-183 VB denotes showing
T19386 164-175 NN denotes experiments
T19385 160-163 PRP-DOLLAR- denotes our
T19384 157-159 IN denotes of
T19383 151-156 NN denotes basis
T19382 147-150 DT denotes the
T19381 144-146 IN denotes on
T19380 142-143 -COMMA- denotes ,
T19379 140-142 NN denotes RA
T19378 137-139 IN denotes in
T19377 131-136 NN denotes IL-17
T19376 128-130 IN denotes of
T19375 115-127 NN denotes upregulation
T19374 111-114 DT denotes the
T19373 108-110 IN denotes of
T19372 97-107 NN denotes arbitrator
T19371 87-96 JJ denotes important
T19370 84-86 DT denotes an
T19369 81-83 VB denotes be
T19368 75-80 MD denotes could
T19367 64-74 NN denotes activation
T19366 58-63 NN denotes NF-κB
T19365 48-57 JJ denotes resultant
T19364 44-47 CC denotes and
T19363 35-43 NN denotes PI3K/Akt
T19362 30-34 IN denotes that
T19361 17-29 VB denotes demonstrated
T19360 9-16 RB denotes clearly
T19359 4-8 NN denotes data
T19358 0-3 PRP-DOLLAR- denotes Our
T19399 257-261 NN denotes PDTC
T19398 254-256 IN denotes by
T19397 245-253 NN denotes promoter
T19396 239-244 NN denotes IL-17
R10393 T19359 T19358 arg1Of data,Our
R10394 T19359 T19361 arg1Of data,demonstrated
R10395 T19361 T19360 arg1Of demonstrated,clearly
R10396 T19363 T19364 arg1Of PI3K/Akt,and
R10397 T19364 T19368 arg1Of and,could
R10398 T19364 T19369 arg1Of and,be
R10399 T19367 T19364 arg2Of activation,and
R10400 T19367 T19365 arg1Of activation,resultant
R10401 T19367 T19366 arg1Of activation,NF-κB
R10402 T19369 T19361 arg2Of be,demonstrated
R10403 T19369 T19362 arg1Of be,that
R10404 T19369 T19368 arg2Of be,could
R10405 T19372 T19369 arg2Of arbitrator,be
R10406 T19372 T19370 arg1Of arbitrator,an
R10407 T19372 T19371 arg1Of arbitrator,important
R10408 T19372 T19373 arg1Of arbitrator,of
R10409 T19372 T19380 arg1Of arbitrator,","
R10410 T19372 T19381 arg1Of arbitrator,on
R10411 T19375 T19373 arg2Of upregulation,of
R10412 T19375 T19374 arg1Of upregulation,the
R10413 T19375 T19376 arg1Of upregulation,of
R10414 T19375 T19378 arg1Of upregulation,in
R10415 T19377 T19376 arg2Of IL-17,of
R10416 T19379 T19378 arg2Of RA,in
R10417 T19383 T19381 arg2Of basis,on
R10418 T19383 T19382 arg1Of basis,the
R10419 T19383 T19384 arg1Of basis,of
R10420 T19383 T19387 arg1Of basis,showing
R10421 T19386 T19384 arg2Of experiments,of
R10422 T19386 T19385 arg1Of experiments,our
R10423 T19389 T19387 arg2Of blocking,showing
R10424 T19389 T19388 arg1Of blocking,simultaneous
R10425 T19389 T19390 arg1Of blocking,of
R10426 T19389 T19394 arg1Of blocking,in
R10427 T19389 T19398 arg1Of blocking,by
R10428 T19393 T19390 arg2Of activity,of
R10429 T19393 T19391 arg1Of activity,NF-κB
R10430 T19393 T19392 arg1Of activity,binding
R10431 T19397 T19394 arg2Of promoter,in
R10432 T19397 T19395 arg1Of promoter,the
R10433 T19397 T19396 arg1Of promoter,IL-17
R10434 T19399 T19400 arg1Of PDTC,and
R10435 T19400 T19398 arg2Of and,by
R10436 T19401 T19400 arg2Of LY294002,and

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T19521 239-244 Protein denotes IL-17
T19520 131-136 Protein denotes IL-17
T19519 40-43 Protein denotes Akt

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T20038 40-43 http://www.uniprot.org/uniprot/Q9Y243 denotes Akt
T20034 40-43 http://www.uniprot.org/uniprot/P31751 denotes Akt
T19960 239-244 http://www.uniprot.org/uniprot/Q16552 denotes IL-17
T19959 131-136 http://www.uniprot.org/uniprot/Q16552 denotes IL-17
T20030 40-43 http://www.uniprot.org/uniprot/P31749 denotes Akt

GO-BP

Id Subject Object Predicate Lexical cue
T18268 58-74 http://purl.obolibrary.org/obo/GO_0051092 denotes NF-κB activation
T18251 35-39 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K

GO-MF

Id Subject Object Predicate Lexical cue
T19605 209-222 http://purl.obolibrary.org/obo/GO_0051059 denotes NF-κB binding
T19602 215-222 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T19589 35-39 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T19553 239-244 http://purl.obolibrary.org/obo/GO_0030367 denotes IL-17
T19552 131-136 http://purl.obolibrary.org/obo/GO_0030367 denotes IL-17

sentences

Id Subject Object Predicate Lexical cue
T18171 0-275 Sentence denotes Our data clearly demonstrated that PI3K/Akt and resultant NF-κB activation could be an important arbitrator of the upregulation of IL-17 in RA, on the basis of our experiments showing simultaneous blocking of NF-κB binding activity in the IL-17 promoter by PDTC and LY294002.
T193 0-275 Sentence denotes Our data clearly demonstrated that PI3K/Akt and resultant NF-κB activation could be an important arbitrator of the upregulation of IL-17 in RA, on the basis of our experiments showing simultaneous blocking of NF-κB binding activity in the IL-17 promoter by PDTC and LY294002.

simple1

Id Subject Object Predicate Lexical cue
T19928 239-244 Protein denotes IL-17
T19927 131-136 Protein denotes IL-17
T19926 40-43 Protein denotes Akt

DLUT931

Id Subject Object Predicate Lexical cue
T20285 115-127 Positive_regulation denotes upregulation
T20230 239-244 Protein denotes IL-17
T20229 131-136 Protein denotes IL-17
T20228 40-43 Protein denotes Akt
R10706 T20229 T20285 themeOf IL-17,upregulation

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T21850 111-143 Positive_regulation denotes the upregulation of IL-17 in RA,
T21828 48-74 Positive_regulation denotes resultant NF-κB activation
T21801 35-43 Protein denotes PI3K/Akt
T21788 239-244 Protein denotes IL-17
T21783 58-63 Protein denotes NF-κB
T21719 128-136 Protein denotes of IL-17
T21716 40-43 Protein denotes Akt
T21703 235-253 Entity denotes the IL-17 promoter
T21684 266-274 Entity denotes LY294002
T21663 35-43 Protein denotes PI3K/Akt
T21625 140-142 Protein denotes RA
R11960 T21783 T21828 themeOf NF-κB,resultant NF-κB activation
R11980 T21703 T21788 partOf the IL-17 promoter,IL-17
R11986 T21719 T21850 themeOf of IL-17,"the upregulation of IL-17 in RA,"

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T21409 274-275 . denotes .
T21408 266-274 NNP denotes LY294002
T21407 262-265 CC denotes and
T21406 257-261 NNP denotes PDTC
T21405 254-256 IN denotes by
T21404 245-253 NN denotes promoter
T21403 239-244 NNP denotes IL-17
T21402 235-238 DT denotes the
T21401 232-234 IN denotes in
T21400 223-231 NN denotes activity
T21399 215-222 JJ denotes binding
T21398 209-214 JJ denotes NF-κB
T21397 206-208 IN denotes of
T21396 197-205 VBG denotes blocking
T21395 184-196 JJ denotes simultaneous
T21394 176-183 VBG denotes showing
T21393 164-175 NNS denotes experiments
T21392 160-163 PRP$ denotes our
T21391 157-159 IN denotes of
T21390 151-156 NN denotes basis
T21389 147-150 DT denotes the
T21388 144-146 IN denotes on
T21387 142-143 , denotes ,
T21386 140-142 NNP denotes RA
T21385 137-139 IN denotes in
T21384 131-136 NNP denotes IL-17
T21383 128-130 IN denotes of
T21382 115-127 NN denotes upregulation
T21381 111-114 DT denotes the
T21380 108-110 IN denotes of
T21379 97-107 NN denotes arbitrator
T21378 87-96 JJ denotes important
T21377 84-86 DT denotes an
T21376 81-83 VB denotes be
T21375 75-80 MD denotes could
T21374 64-74 NN denotes activation
T21373 58-63 NN denotes NF-κB
T21372 48-57 JJ denotes resultant
T21371 44-47 CC denotes and
T21370 35-43 NNP denotes PI3K/Akt
T21369 30-34 IN denotes that
T21368 17-29 VBD denotes demonstrated
T21367 9-16 RB denotes clearly
T21366 4-8 NNS denotes data
T21365 0-3 PRP$ denotes Our
R11775 T21365 T21366 poss Our,data
R11780 T21366 T21368 nsubj data,demonstrated
R11781 T21367 T21368 advmod clearly,demonstrated
R11783 T21368 T21368 ROOT demonstrated,demonstrated
R11786 T21369 T21376 mark that,be
R11789 T21370 T21376 nsubj PI3K/Akt,be
R11793 T21371 T21370 cc and,PI3K/Akt
R11794 T21372 T21374 amod resultant,activation
R11795 T21373 T21374 compound NF-κB,activation
R11797 T21374 T21370 conj activation,PI3K/Akt
R11800 T21375 T21376 aux could,be
R11811 T21376 T21368 ccomp be,demonstrated
R11813 T21377 T21379 det an,arbitrator
R11814 T21378 T21379 amod important,arbitrator
R11817 T21379 T21376 attr arbitrator,be
R11821 T21380 T21379 prep of,arbitrator
R11822 T21381 T21382 det the,upregulation
R11823 T21382 T21380 pobj upregulation,of
R11828 T21383 T21382 prep of,upregulation
R11831 T21384 T21383 pobj IL-17,of
R11833 T21385 T21382 prep in,upregulation
R11835 T21386 T21385 pobj RA,in
R11840 T21387 T21379 punct ",",arbitrator
R11841 T21388 T21379 prep on,arbitrator
R11843 T21389 T21390 det the,basis
R11844 T21390 T21388 pobj basis,on
R11845 T21391 T21390 prep of,basis
R11846 T21392 T21393 poss our,experiments
R11848 T21393 T21391 pobj experiments,of
R11849 T21394 T21393 acl showing,experiments
R11853 T21395 T21396 amod simultaneous,blocking
R11855 T21396 T21394 dobj blocking,showing
R11858 T21397 T21396 prep of,blocking
R11860 T21398 T21400 amod NF-κB,activity
R11862 T21399 T21400 amod binding,activity
R11864 T21400 T21397 pobj activity,of
R11866 T21401 T21400 prep in,activity
R11868 T21402 T21404 det the,promoter
R11871 T21403 T21404 compound IL-17,promoter
R11872 T21404 T21401 pobj promoter,in
R11874 T21405 T21396 prep by,blocking
R11883 T21406 T21405 pobj PDTC,by
R11884 T21407 T21406 cc and,PDTC
R11887 T21408 T21406 conj LY294002,PDTC
R11890 T21409 T21368 punct .,demonstrated

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T19789 197-205 Negative_regulation denotes blocking
T19788 197-205 Negative_regulation denotes blocking
T19787 197-205 Negative_regulation denotes blocking
T19786 197-205 Negative_regulation denotes blocking
T19785 215-222 Binding denotes binding
T19784 215-222 Binding denotes binding
T19783 215-222 Binding denotes binding
T19782 215-222 Binding denotes binding
T19781 64-74 Positive_regulation denotes activation
T19780 239-253 Protein denotes IL-17 promoter
T19779 209-214 Protein denotes NF-κB
T19778 58-63 Protein denotes NF-κB
T19777 40-43 Protein denotes Akt
T19776 35-39 Protein denotes PI3K
R10571 T19777 T19784 themeOf Akt,binding
R10572 T19778 T19781 themeOf NF-κB,activation
R10573 T19779 T19782 themeOf NF-κB,binding
R10574 T19779 T19784 themeOf NF-κB,binding
R10575 T19779 T19785 themeOf NF-κB,binding
R10576 T19780 T19783 themeOf IL-17 promoter,binding
R10577 T19780 T19785 themeOf IL-17 promoter,binding
R10578 T19782 T19786 themeOf binding,blocking
R10579 T19783 T19787 themeOf binding,blocking
R10580 T19784 T19788 themeOf binding,blocking
R10581 T19785 T19789 themeOf binding,blocking

testone

Id Subject Object Predicate Lexical cue
T17026 245-253 Entity denotes promoter
T17025 215-222 Binding denotes binding
T17024 197-205 Negative_regulation denotes blocking
T17023 115-127 Positive_regulation denotes upregulation
T16964 239-244 Protein denotes IL-17
T16963 131-136 Protein denotes IL-17
T16962 40-43 Protein denotes Akt
R9237 T16963 T17023 themeOf IL-17,upregulation
R9264 T17025 T17024 themeOf binding,blocking
R9265 T17026 T16964 partOf promoter,IL-17
R9266 T17026 T17025 themeOf promoter,binding