PMC:1064895 / 20649-21991
Annnotations
test3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T15581 | 1305-1314 | Positive_regulation | denotes | activated |
| T15580 | 1291-1301 | Gene_expression | denotes | production |
| T15579 | 1285-1290 | Protein | denotes | IL-17 |
| T15578 | 1190-1194 | Protein | denotes | CD28 |
| T15577 | 1120-1124 | Protein | denotes | AP-1 |
| T15576 | 1048-1053 | Protein | denotes | IκB-α |
| T15575 | 1033-1044 | Protein_catabolism | denotes | degradation |
| T15574 | 1019-1029 | Negative_regulation | denotes | inhibition |
| T15573 | 1006-1011 | Protein | denotes | IκB-α |
| T15572 | 959-964 | Protein | denotes | IL-17 |
| T15571 | 935-942 | Binding | denotes | binding |
| T15570 | 919-924 | Negative_regulation | denotes | block |
| T15569 | 697-701 | Protein | denotes | CD28 |
| T15568 | 578-583 | Protein | denotes | c-Rel |
| T15567 | 551-554 | Protein | denotes | p50 |
| T15566 | 543-546 | Protein | denotes | p65 |
| T15565 | 432-437 | Protein | denotes | IL-17 |
| T15564 | 412-419 | Binding | denotes | binding |
| T15563 | 402-411 | Positive_regulation | denotes | increased |
| T15562 | 375-379 | Protein | denotes | CD28 |
| T15561 | 282-287 | Protein | denotes | IL-17 |
| T15560 | 163-173 | Gene_expression | denotes | expression |
| T15559 | 157-162 | Protein | denotes | IL-17 |
| T15558 | 148-156 | Negative_regulation | denotes | inducing |
| T15557 | 121-126 | Protein | denotes | IL-15 |
| T15556 | 113-116 | Protein | denotes | PHA |
| T15555 | 91-95 | Protein | denotes | CD28 |
| T15551 | 1285-1290 | Protein | denotes | IL-17 |
| T15550 | 1190-1194 | Protein | denotes | CD28 |
| T15549 | 1120-1124 | Protein | denotes | AP-1 |
| T15548 | 1048-1053 | Protein | denotes | IκB-α |
| T15547 | 1006-1011 | Protein | denotes | IκB-α |
| T15546 | 959-964 | Protein | denotes | IL-17 |
| T15545 | 697-701 | Protein | denotes | CD28 |
| T15544 | 578-583 | Protein | denotes | c-Rel |
| T15543 | 551-554 | Protein | denotes | p50 |
| T15542 | 543-546 | Protein | denotes | p65 |
| T15541 | 432-437 | Protein | denotes | IL-17 |
| T15540 | 375-379 | Protein | denotes | CD28 |
| T15539 | 282-287 | Protein | denotes | IL-17 |
| T15538 | 157-162 | Protein | denotes | IL-17 |
| T15537 | 121-126 | Protein | denotes | IL-15 |
| T15536 | 113-116 | Protein | denotes | PHA |
| T15535 | 91-95 | Protein | denotes | CD28 |
| R8555 | T15556 | T15558 | causeOf | PHA,inducing |
| R8556 | T15559 | T15560 | themeOf | IL-17,expression |
| R8557 | T15560 | T15558 | themeOf | expression,inducing |
| R8558 | T15564 | T15563 | themeOf | binding,increased |
| R8559 | T15571 | T15570 | themeOf | binding,block |
| R8560 | T15575 | T15574 | themeOf | degradation,inhibition |
| R8561 | T15576 | T15574 | themeOf | IκB-α,inhibition |
| R8562 | T15576 | T15575 | themeOf | IκB-α,degradation |
| R8563 | T15579 | T15580 | themeOf | IL-17,production |
BioNLP16_Messiy
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16333 | 1285-1290 | Protein | denotes | IL-17 |
| T16342 | 1291-1301 | Gene_expression | denotes | production |
| T16341 | 1019-1029 | Negative_regulation | denotes | inhibition |
| T16340 | 1033-1044 | Protein_catabolism | denotes | degradation |
| T16339 | 412-419 | Binding | denotes | binding |
| T16338 | 402-411 | Positive_regulation | denotes | increased |
| T16337 | 148-156 | Positive_regulation | denotes | inducing |
| T16336 | 59-68 | Positive_regulation | denotes | activated |
| T16335 | 163-173 | Gene_expression | denotes | expression |
| T16332 | 1190-1194 | Protein | denotes | CD28 |
| T16331 | 1120-1124 | Protein | denotes | AP-1 |
| T16330 | 1048-1053 | Protein | denotes | IκB-α |
| T16329 | 1006-1011 | Protein | denotes | IκB-α |
| T16328 | 959-964 | Protein | denotes | IL-17 |
| T16327 | 697-701 | Protein | denotes | CD28 |
| T16326 | 578-583 | Protein | denotes | c-Rel |
| T16325 | 551-554 | Protein | denotes | p50 |
| T16324 | 543-546 | Protein | denotes | p65 |
| T16323 | 375-379 | Protein | denotes | CD28 |
| T16322 | 432-437 | Protein | denotes | IL-17 |
| T16321 | 282-287 | Protein | denotes | IL-17 |
| T16320 | 157-162 | Protein | denotes | IL-17 |
| T16319 | 121-126 | Protein | denotes | IL-15 |
| T16318 | 113-116 | Protein | denotes | PHA |
| T16317 | 91-95 | Protein | denotes | CD28 |
| R8862 | T16318 | T16336 | themeOf | PHA,activated |
| R8863 | T16319 | T16336 | causeOf | IL-15,activated |
| R8864 | T16320 | T16335 | themeOf | IL-17,expression |
| R8865 | T16322 | T16339 | themeOf | IL-17,binding |
| R8866 | T16330 | T16340 | themeOf | IκB-α,degradation |
| R8867 | T16333 | T16342 | themeOf | IL-17,production |
| R8868 | T16335 | T16337 | themeOf | expression,inducing |
| R8869 | T16339 | T16338 | themeOf | binding,increased |
| R8870 | T16340 | T16341 | themeOf | degradation,inhibition |
BioNLP16_DUT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16808 | 1291-1301 | Gene_expression | denotes | production |
| T16807 | 1019-1029 | Negative_regulation | denotes | inhibition |
| T16806 | 1033-1044 | Protein_catabolism | denotes | degradation |
| T16805 | 919-924 | Negative_regulation | denotes | block |
| T16804 | 412-419 | Binding | denotes | binding |
| T16803 | 148-156 | Positive_regulation | denotes | inducing |
| T16802 | 163-173 | Gene_expression | denotes | expression |
| T16800 | 1285-1290 | Protein | denotes | IL-17 |
| T16799 | 1190-1194 | Protein | denotes | CD28 |
| T16798 | 1120-1124 | Protein | denotes | AP-1 |
| T16797 | 1048-1053 | Protein | denotes | IκB-α |
| T16796 | 1006-1011 | Protein | denotes | IκB-α |
| T16795 | 959-964 | Protein | denotes | IL-17 |
| T16794 | 697-701 | Protein | denotes | CD28 |
| T16793 | 578-583 | Protein | denotes | c-Rel |
| T16792 | 551-554 | Protein | denotes | p50 |
| T16791 | 543-546 | Protein | denotes | p65 |
| T16790 | 375-379 | Protein | denotes | CD28 |
| T16789 | 432-437 | Protein | denotes | IL-17 |
| T16788 | 282-287 | Protein | denotes | IL-17 |
| T16787 | 157-162 | Protein | denotes | IL-17 |
| T16786 | 121-126 | Protein | denotes | IL-15 |
| T16785 | 113-116 | Protein | denotes | PHA |
| T16784 | 91-95 | Protein | denotes | CD28 |
| R9192 | T16787 | T16802 | themeOf | IL-17,expression |
| R9193 | T16789 | T16804 | themeOf | IL-17,binding |
| R9194 | T16795 | T16805 | themeOf | IL-17,block |
| R9195 | T16797 | T16806 | themeOf | IκB-α,degradation |
| R9196 | T16800 | T16808 | themeOf | IL-17,production |
| R9197 | T16802 | T16803 | themeOf | expression,inducing |
| R9198 | T16806 | T16807 | themeOf | degradation,inhibition |
biosemtest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T15816 | 966-971 | UMLS/C1825592 | denotes | romot |
| T15815 | 435-440 | UMLS/C1825592 | denotes | 17 pr |
| T15814 | 284-289 | UMLS/C1825592 | denotes | -17. |
| T15813 | 158-163 | UMLS/C1825592 | denotes | L-17 |
| T15811 | 1257-1261 | UMLS/C0024497 | denotes | llul |
| T15788 | 312-328 | UMLS/C1518434 | denotes | clear extracts f |
| T15787 | 478-486 | UMLS/C0332298 | denotes | trols (l |
| T15786 | 770-774 | UMLS/C1517892 | denotes | bet |
| T15785 | 149-157 | UMLS/C0205263 | denotes | nducing |
| T15784 | 1191-1195 | UMLS/C0332287 | denotes | D28 |
| T15783 | 691-695 | UMLS/C0332287 | denotes | ant |
| T15782 | 367-371 | UMLS/C0332287 | denotes | us a |
| T15781 | 82-86 | UMLS/C0332287 | denotes | lus |
| T15780 | 1042-1053 | UMLS/C0243125 | denotes | on of IκB-α |
| T15779 | 546-549 | UMLS/C1335610 | denotes | an |
| T15778 | 851-858 | UMLS/C0243122 | denotes | g activ |
| T15777 | 414-421 | UMLS/C0243122 | denotes | nding o |
| T15776 | 600-606 | UMLS/C2347086 | denotes | mal PB |
| T15775 | 918-924 | UMLS/C1521826 | denotes | block |
| T15774 | 1257-1261 | UMLS/C0205225 | denotes | llul |
| T15773 | 1028-1038 | UMLS/C1628982 | denotes | n of degra |
| T15772 | 404-413 | UMLS/C0205217 | denotes | creased b |
| T15771 | 1093-1097 | UMLS/C1692345 | denotes | Fig. |
| T15770 | 616-620 | UMLS/C1692345 | denotes | e pa |
| T15769 | 510-515 | UMLS/C0005507 | denotes | ay de |
| T15768 | 223-228 | UMLS/C0005507 | denotes | ssay |
| T15767 | 1098-1102 | UMLS/C1704250 | denotes | 7c). |
| T15766 | 600-606 | UMLS/C0439166 | denotes | mal PB |
| T15765 | 1327-1331 | UMLS/C1321301 | denotes | tien |
| T15764 | 739-743 | UMLS/C1321301 | denotes | (Fi |
| T15763 | 607-611 | UMLS/C1321301 | denotes | C th |
| T15762 | 337-341 | UMLS/C1321301 | denotes | MC s |
| T15761 | 950-958 | UMLS/C0439167 | denotes | y in the |
| T15760 | 859-867 | UMLS/C0439167 | denotes | ty after |
| T15759 | 788-796 | UMLS/C0439167 | denotes | vity and |
| T15758 | 546-549 | UP/P48018 | denotes | an |
| T15757 | 1136-1143 | UMLS/C1704259 | denotes | not ac |
| T15755 | 478-486 | UMLS/C0243148 | denotes | trols (l |
| T15754 | 1207-1211 | UMLS/C1511726 | denotes | own) |
| T15753 | 822-826 | UMLS/C0596608 | denotes | to d |
| T15752 | 230-234 | UMLS/C0596608 | denotes | MSA) |
| T15751 | 554-557 | UMLS/C1539081 | denotes | (l |
| T15750 | 537-542 | UMLS/C0439645 | denotes | ds in |
| T15749 | 1257-1261 | UMLS/C1542147 | denotes | llul |
| T15748 | 546-549 | UMLS/C1420556 | denotes | an |
| T15747 | 1276-1293 | UMLS/C0037080 | denotes | thway in IL-17 pr |
| T15746 | 42-59 | UMLS/C0037080 | denotes | ignaling pathway |
| T15745 | 581-586 | UMLS/C0035018 | denotes | el (l |
| T15744 | 246-257 | UMLS/C0524637 | denotes | cognition s |
| T15743 | 1131-1135 | UP/P21525 | denotes | y wa |
| T15741 | 546-549 | UMLS/C0599933 | denotes | an |
| T15740 | 783-787 | UMLS/C1705325 | denotes | act |
| T15739 | 633-641 | UMLS/C1441672 | denotes | erved, b |
| T15738 | 478-486 | UMLS/C1547100 | denotes | trols (l |
| T15737 | 770-774 | UMLS/C0208973 | denotes | bet |
| T15736 | 851-858 | UMLS/C1689898 | denotes | g activ |
| T15735 | 414-421 | UMLS/C1689898 | denotes | nding o |
| T15734 | 651-657 | UMLS/C0449286 | denotes | ree of |
| T15733 | 600-606 | UMLS/C1873497 | denotes | mal PB |
| T15732 | 546-549 | UP/P21521 | denotes | an |
| T15731 | 950-958 | UMLS/C0441655 | denotes | y in the |
| T15730 | 859-867 | UMLS/C0441655 | denotes | ty after |
| T15729 | 788-796 | UMLS/C0441655 | denotes | vity and |
| T15728 | 1028-1038 | UMLS/C0021467 | denotes | n of degra |
| T15727 | 1028-1038 | UMLS/C0021469 | denotes | n of degra |
| T15726 | 1262-1275 | UMLS/C0178719 | denotes | r signaling p |
| T15725 | 28-41 | UMLS/C0178719 | denotes | ntracellular |
| T15724 | 1104-1107 | UMLS/C0349966 | denotes | n c |
| T15723 | 982-985 | UMLS/C0349966 | denotes | ). |
| T15722 | 745-748 | UMLS/C0349966 | denotes | 7b |
| T15721 | 303-306 | UMLS/C0349966 | denotes | g. |
| T15720 | 1131-1135 | UP/A8MPH9 | denotes | y wa |
| T15718 | 404-413 | UMLS/C0442805 | denotes | creased b |
| T15717 | 404-413 | UMLS/C0442808 | denotes | creased b |
| T15716 | 1098-1102 | UMLS/C0449243 | denotes | 7c). |
| T15715 | 822-826 | UMLS/C0949632 | denotes | to d |
| T15714 | 230-234 | UMLS/C0949632 | denotes | MSA) |
| T15713 | 454-464 | UMLS/C1707455 | denotes | parison wi |
| T15712 | 1098-1102 | UMLS/C0040223 | denotes | 7c). |
| T15711 | 478-486 | UMLS/C1550141 | denotes | trols (l |
| T15710 | 537-542 | UMLS/C0185014 | denotes | ds in |
| T15709 | 529-536 | UMLS/C0333051 | denotes | fted ba |
| T15708 | 918-924 | UMLS/C1254351 | denotes | block |
| T15707 | 1131-1135 | UMLS/C0087140 | denotes | y wa |
| T15705 | 651-657 | UMLS/C0542560 | denotes | ree of |
| T15704 | 258-263 | UMLS/C1546778 | denotes | tes i |
| T15703 | 122-127 | UMLS/C1149222 | denotes | L-15, |
| T15701 | 114-117 | UMLS/C0030779 | denotes | HA |
| T15700 | 758-765 | UMLS/C1446409 | denotes | irm the |
| T15699 | 651-657 | UMLS/C0441889 | denotes | ree of |
| T15698 | 546-549 | UP/P47191 | denotes | an |
| T15697 | 4-15 | UMLS/C1292732 | denotes | nvestigate |
| T15696 | 122-127 | UMLS/C0254610 | denotes | L-15, |
| T15695 | 164-174 | UMLS/C0185117 | denotes | xpression, |
| T15694 | 510-515 | UMLS/C1510438 | denotes | ay de |
| T15693 | 223-228 | UMLS/C1510438 | denotes | ssay |
| T15692 | 621-628 | UMLS/C0449774 | denotes | tern wa |
| T15691 | 554-557 | UP/P83939 | denotes | (l |
| T15690 | 1317-1326 | UMLS/C1879547 | denotes | MC from p |
| T15689 | 1152-1161 | UMLS/C1879547 | denotes | y stimula |
| T15688 | 668-678 | UMLS/C1879547 | denotes | vation by |
| T15687 | 60-69 | UMLS/C1879547 | denotes | ctivated |
| T15685 | 122-127 | UMLS/C1334105 | denotes | L-15, |
| T15684 | 258-263 | UMLS/C2347790 | denotes | tes i |
| T15683 | 1131-1135 | UMLS/C0162508 | denotes | y wa |
| T15681 | 554-557 | UMLS/C1417708 | denotes | (l |
| T15680 | 868-883 | UMLS/C0001758 | denotes | treatment with |
| T15679 | 133-144 | UMLS/C1273518 | denotes | esponsible |
| T15678 | 1131-1135 | UMLS/C1333571 | denotes | y wa |
| T15676 | 1165-1176 | UMLS/C1948023 | denotes | with anti- |
| T15675 | 342-352 | UMLS/C1948023 | denotes | imulated w |
| T15674 | 992-1008 | UMLS/C0005863 | denotes | blotting for Iκ |
| T15673 | 478-486 | UMLS/C0009932 | denotes | trols (l |
| T15672 | 783-787 | UP/P42336 | denotes | act |
| T15671 | 812-821 | UMLS/C0884358 | denotes | rmed EMSA |
| T15670 | 179-188 | UMLS/C0884358 | denotes | erformed |
| T15669 | 992-1008 | UMLS/C0949466 | denotes | blotting for Iκ |
| T15668 | 1042-1053 | UMLS/C0699900 | denotes | on of IκB-α |
| T15667 | 1068-1076 | UMLS/C0251991 | denotes | d PDTC a |
| T15666 | 894-902 | UMLS/C0251991 | denotes | 02 and P |
| T15665 | 966-971 | UMLS/C1522571 | denotes | romot |
| T15664 | 435-440 | UMLS/C1522571 | denotes | 17 pr |
| T15663 | 284-289 | UMLS/C1522571 | denotes | -17. |
| T15662 | 158-163 | UMLS/C1522571 | denotes | L-17 |
| T15660 | 1165-1176 | UMLS/C1292856 | denotes | with anti- |
| T15659 | 1081-1085 | UMLS/C0084183 | denotes | sam |
| T15658 | 907-911 | UMLS/C0084183 | denotes | Both |
| T15657 | 1262-1275 | UMLS/C0175996 | denotes | r signaling p |
| T15656 | 28-41 | UMLS/C0175996 | denotes | ntracellular |
| T15655 | 918-924 | UMLS/C0450442 | denotes | block |
| T15654 | 966-971 | UMLS/C0384648 | denotes | romot |
| T15653 | 435-440 | UMLS/C0384648 | denotes | 17 pr |
| T15652 | 284-289 | UMLS/C0384648 | denotes | -17. |
| T15651 | 158-163 | UMLS/C0384648 | denotes | L-17 |
| T15649 | 950-958 | UMLS/C1561536 | denotes | y in the |
| T15648 | 859-867 | UMLS/C1561536 | denotes | ty after |
| T15647 | 788-796 | UMLS/C1561536 | denotes | vity and |
| T15646 | 164-174 | UMLS/C0017262 | denotes | xpression, |
| T15645 | 783-787 | UMLS/C1368105 | denotes | act |
| T15644 | 812-821 | UMLS/C1550369 | denotes | rmed EMSA |
| T15643 | 179-188 | UMLS/C1550369 | denotes | erformed |
| T15642 | 830-839 | UMLS/C0521095 | denotes | mine the |
| T15641 | 925-930 | UMLS/C0332206 | denotes | NF-κB |
| T15640 | 758-765 | UMLS/C0521093 | denotes | irm the |
| T15639 | 925-930 | UMLS/C1706084 | denotes | NF-κB |
| T15638 | 1098-1102 | UMLS/C1548318 | denotes | 7c). |
| T15637 | 258-263 | UMLS/C0205145 | denotes | tes i |
| T15636 | 510-515 | UMLS/C0243073 | denotes | ay de |
| T15635 | 223-228 | UMLS/C0243073 | denotes | ssay |
| T15634 | 758-765 | UMLS/C1456348 | denotes | irm the |
| T15633 | 1276-1293 | UMLS/C0086982 | denotes | thway in IL-17 pr |
| T15632 | 42-59 | UMLS/C0086982 | denotes | ignaling pathway |
| T15631 | 851-858 | UMLS/C1167622 | denotes | g activ |
| T15630 | 414-421 | UMLS/C1167622 | denotes | nding o |
| T15629 | 925-930 | UMLS/C1533157 | denotes | NF-κB |
| T15628 | 966-971 | UMLS/C1623218 | denotes | romot |
| T15627 | 435-440 | UMLS/C1623218 | denotes | 17 pr |
| T15626 | 284-289 | UMLS/C1623218 | denotes | -17. |
| T15625 | 158-163 | UMLS/C1623218 | denotes | L-17 |
| T15623 | 554-557 | UP/Q05894 | denotes | (l |
| T15622 | 651-657 | UMLS/C1561545 | denotes | ree of |
| T15621 | 554-557 | UP/P23061 | denotes | (l |
| T15620 | 308-310 | UMLS/C1553639 | denotes | , |
| T15619 | 1098-1102 | UMLS/C1547403 | denotes | 7c). |
| T15618 | 1098-1102 | UMLS/C1632851 | denotes | 7c). |
| T15617 | 600-606 | UMLS/C1704701 | denotes | mal PB |
| T15616 | 98-112 | UMLS/C0009630 | denotes | oncanavalin A, |
| T15615 | 643-646 | UMLS/C0005341 | denotes | th |
| T15614 | 783-787 | UMLS/C0285761 | denotes | act |
| T15613 | 546-549 | UP/P41823 | denotes | an |
| T15612 | 827-829 | UMLS/C0319022 | denotes | te |
| T15611 | 755-757 | UMLS/C0319022 | denotes | on |
| T15610 | 432-434 | UMLS/C0319022 | denotes | IL |
| T15609 | 1-3 | UMLS/C0319022 | denotes | o |
| T15608 | 1098-1102 | UMLS/C0392761 | denotes | 7c). |
| T15607 | 925-930 | UMLS/C0028778 | denotes | NF-κB |
| T15606 | 600-606 | UMLS/C1550457 | denotes | mal PB |
| T15605 | 925-930 | UMLS/C0233660 | denotes | NF-κB |
| T15604 | 972-980 | UMLS/C0086860 | denotes | r (Fig. |
| T15603 | 441-450 | UMLS/C0086860 | denotes | moters in |
| T15602 | 271-280 | UMLS/C0086860 | denotes | omoters o |
| T15601 | 1131-1135 | UMLS/C0812312 | denotes | y wa |
| T15599 | 758-765 | UMLS/C0750484 | denotes | irm the |
| T15598 | 258-263 | UMLS/C1515974 | denotes | tes i |
| T15597 | 851-858 | UMLS/C1145667 | denotes | g activ |
| T15596 | 414-421 | UMLS/C1145667 | denotes | nding o |
| T15595 | 1093-1097 | UMLS/C0445247 | denotes | Fig. |
| T15594 | 616-620 | UMLS/C0445247 | denotes | e pa |
| T15593 | 600-606 | UMLS/C1551394 | denotes | mal PB |
| T15592 | 851-858 | UMLS/C2349209 | denotes | g activ |
| T15591 | 414-421 | UMLS/C2349209 | denotes | nding o |
| T15590 | 715-722 | UMLS/C0522510 | denotes | nse tha |
| T15589 | 1131-1135 | UMLS/C0085828 | denotes | y wa |
| T15586 | 554-557 | UMLS/C1705525 | denotes | (l |
| T15585 | 1117-1125 | UMLS/C1979874 | denotes | he AP-1 |
| T15584 | 478-486 | UMLS/C1882979 | denotes | trols (l |
| T15583 | 938-949 | UMLS/C1148673 | denotes | ding activi |
| T15582 | 770-774 | UMLS/C1704666 | denotes | bet |
| T15810 | 1297-1313 | UMLS/C1819444 | denotes | tion by activate |
| T15809 | 554-557 | UP/Q28618 | denotes | (l |
| T15808 | 478-486 | UMLS/C2587213 | denotes | trols (l |
| T15807 | 918-924 | UMLS/C1551364 | denotes | block |
| T15806 | 529-536 | UMLS/C2347509 | denotes | fted ba |
| T15805 | 546-549 | UP/P21707 | denotes | an |
| T15804 | 537-542 | UMLS/C0175723 | denotes | ds in |
| T15803 | 600-606 | UMLS/C0205307 | denotes | mal PB |
| T15802 | 546-549 | UP/P46096 | denotes | an |
| T15801 | 546-549 | UP/P21579 | denotes | an |
| T15800 | 651-657 | UMLS/C2348088 | denotes | ree of |
| T15799 | 1136-1143 | UMLS/C1705987 | denotes | not ac |
| T15797 | 783-787 | UMLS/C1150481 | denotes | act |
| T15796 | 1212-1215 | UMLS/C1518422 | denotes | de |
| T15795 | 1148-1151 | UMLS/C1518422 | denotes | ed |
| T15794 | 574-577 | UMLS/C1518422 | denotes | in |
| T15793 | 588-592 | UMLS/C1708639 | denotes | e 5) |
| T15792 | 559-564 | UMLS/C1708639 | denotes | es 3 |
| T15791 | 488-492 | UMLS/C1708639 | denotes | e 1) |
| T15790 | 383-387 | UMLS/C1708639 | denotes | ne 2 |
| T15789 | 114-117 | UMLS/C0031858 | denotes | HA |
pmc-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16026 | 648-654 | NN | denotes | degree |
| T16025 | 644-647 | DT | denotes | the |
| T16024 | 640-643 | CC | denotes | but |
| T16023 | 638-639 | -COMMA- | denotes | , |
| T16022 | 630-638 | VB | denotes | observed |
| T16021 | 626-629 | VB | denotes | was |
| T16020 | 618-625 | NN | denotes | pattern |
| T16019 | 613-617 | JJ | denotes | same |
| T16018 | 609-612 | DT | denotes | the |
| T16017 | 604-608 | NN | denotes | PBMC |
| T16016 | 597-603 | JJ | denotes | normal |
| T16015 | 594-596 | IN | denotes | In |
| T16014 | 591-592 | -RRB- | denotes | ) |
| T16013 | 590-591 | CD | denotes | 5 |
| T16012 | 585-589 | NN | denotes | lane |
| T16011 | 584-585 | -LRB- | denotes | ( |
| T16010 | 578-583 | NN | denotes | c-Rel |
| T16009 | 575-577 | IN | denotes | in |
| T16008 | 571-574 | RB | denotes | not |
| T16007 | 569-570 | -RRB- | denotes | ) |
| T16006 | 568-569 | CD | denotes | 4 |
| T16005 | 564-567 | CC | denotes | and |
| T16004 | 562-563 | CD | denotes | 3 |
| T16003 | 556-561 | NN | denotes | lanes |
| T16002 | 555-556 | -LRB- | denotes | ( |
| T16001 | 551-554 | NN | denotes | p50 |
| T16000 | 547-550 | CC | denotes | and |
| T15999 | 543-546 | NN | denotes | p65 |
| T15998 | 540-542 | IN | denotes | in |
| T15997 | 534-539 | NN | denotes | bands |
| T15996 | 526-533 | VB | denotes | shifted |
| T15995 | 513-525 | VB | denotes | demonstrated |
| T15994 | 507-512 | NN | denotes | assay |
| T15993 | 496-506 | NN | denotes | supershift |
| T15992 | 494-495 | DT | denotes | A |
| T15991 | 491-492 | -RRB- | denotes | ) |
| T15990 | 490-491 | CD | denotes | 1 |
| T15989 | 485-489 | NN | denotes | lane |
| T15988 | 484-485 | -LRB- | denotes | ( |
| T15987 | 475-483 | NN | denotes | controls |
| T15986 | 472-474 | IN | denotes | of |
| T15985 | 467-471 | DT | denotes | that |
| T15984 | 462-466 | IN | denotes | with |
| T15983 | 451-461 | NN | denotes | comparison |
| T15982 | 448-450 | IN | denotes | in |
| T15981 | 438-447 | NN | denotes | promoters |
| T15980 | 432-437 | NN | denotes | IL-17 |
| T15979 | 429-431 | TO | denotes | to |
| T15978 | 423-428 | NN | denotes | NF-κB |
| T15977 | 420-422 | IN | denotes | of |
| T15976 | 412-419 | NN | denotes | binding |
| T15975 | 402-411 | VB | denotes | increased |
| T15974 | 389-401 | VB | denotes | demonstrated |
| T15973 | 387-388 | -RRB- | denotes | ) |
| T15972 | 386-387 | CD | denotes | 2 |
| T15971 | 381-385 | NN | denotes | lane |
| T15970 | 380-381 | -LRB- | denotes | ( |
| T15969 | 370-379 | NN | denotes | anti-CD28 |
| T15968 | 365-369 | CC | denotes | plus |
| T15967 | 356-364 | JJ | denotes | anti-CD3 |
| T15966 | 351-355 | IN | denotes | with |
| T15965 | 340-350 | VB | denotes | stimulated |
| T15964 | 335-339 | NN | denotes | PBMC |
| T15963 | 332-334 | NN | denotes | RA |
| T15962 | 327-331 | IN | denotes | from |
| T15961 | 318-326 | NN | denotes | extracts |
| T15960 | 310-317 | JJ | denotes | nuclear |
| T15959 | 308-309 | -COMMA- | denotes | , |
| T15958 | 306-308 | NNP | denotes | 7a |
| T15957 | 301-305 | NNP | denotes | Fig. |
| T15956 | 298-300 | IN | denotes | in |
| T15955 | 292-297 | VB | denotes | shown |
| T15954 | 289-291 | IN | denotes | As |
| T15953 | 282-287 | NN | denotes | IL-17 |
| T15952 | 279-281 | IN | denotes | of |
| T15951 | 269-278 | NN | denotes | promoters |
| T15950 | 265-268 | DT | denotes | the |
| T15949 | 262-264 | IN | denotes | in |
| T15948 | 256-261 | NN | denotes | sites |
| T15947 | 244-255 | NN | denotes | recognition |
| T15946 | 238-243 | NN | denotes | NF-κB |
| T15945 | 235-237 | IN | denotes | of |
| T15944 | 233-234 | -RRB- | denotes | ) |
| T15943 | 229-233 | NN | denotes | EMSA |
| T15942 | 228-229 | -LRB- | denotes | ( |
| T15941 | 222-227 | NN | denotes | assay |
| T15940 | 207-221 | NN | denotes | mobility-shift |
| T15939 | 191-206 | JJ | denotes | electrophoretic |
| T15938 | 188-190 | DT | denotes | an |
| T15937 | 178-187 | VB | denotes | performed |
| T15936 | 175-177 | PRP | denotes | we |
| T15935 | 173-174 | -COMMA- | denotes | , |
| T15934 | 163-173 | NN | denotes | expression |
| T15933 | 157-162 | NN | denotes | IL-17 |
| T15932 | 148-156 | VB | denotes | inducing |
| T15931 | 144-147 | IN | denotes | for |
| T15930 | 132-143 | JJ | denotes | responsible |
| T15929 | 128-131 | CC | denotes | and |
| T15928 | 126-127 | -COMMA- | denotes | , |
| T15927 | 121-126 | NN | denotes | IL-15 |
| T15926 | 117-120 | CC | denotes | and |
| T15925 | 113-116 | NN | denotes | PHA |
| T15924 | 111-112 | -COMMA- | denotes | , |
| T15923 | 110-111 | NN | denotes | A |
| T15922 | 97-109 | NN | denotes | concanavalin |
| T15921 | 95-96 | -COMMA- | denotes | , |
| T15920 | 86-95 | NN | denotes | anti-CD28 |
| T15919 | 81-85 | CC | denotes | plus |
| T15918 | 72-80 | JJ | denotes | anti-CD3 |
| T15917 | 69-71 | IN | denotes | by |
| T15916 | 59-68 | VB | denotes | activated |
| T15915 | 51-58 | NN | denotes | pathway |
| T15914 | 41-50 | NN | denotes | signaling |
| T15913 | 27-40 | JJ | denotes | intracellular |
| T15912 | 23-26 | DT | denotes | the |
| T15911 | 15-22 | RB | denotes | further |
| T15910 | 3-14 | VB | denotes | investigate |
| T15909 | 0-2 | TO | denotes | To |
| T16086 | 985-992 | NN | denotes | Western |
| T16085 | 982-983 | -RRB- | denotes | ) |
| T16147 | 1339-1341 | NN | denotes | RA |
| T16146 | 1334-1338 | IN | denotes | with |
| T16145 | 1325-1333 | NN | denotes | patients |
| T16144 | 1320-1324 | IN | denotes | from |
| T16143 | 1315-1319 | NN | denotes | PBMC |
| T16142 | 1305-1314 | VB | denotes | activated |
| T16141 | 1302-1304 | IN | denotes | by |
| T16140 | 1291-1301 | NN | denotes | production |
| T16139 | 1285-1290 | NN | denotes | IL-17 |
| T16138 | 1282-1284 | IN | denotes | in |
| T16137 | 1274-1281 | NN | denotes | pathway |
| T16136 | 1264-1273 | NN | denotes | signaling |
| T16135 | 1250-1263 | JJ | denotes | intracellular |
| T16134 | 1245-1249 | JJ | denotes | main |
| T16133 | 1241-1244 | DT | denotes | the |
| T16132 | 1238-1240 | VB | denotes | is |
| T16131 | 1232-1237 | NN | denotes | NF-κB |
| T16130 | 1227-1231 | IN | denotes | that |
| T16129 | 1213-1226 | VB | denotes | demonstrating |
| T16128 | 1211-1212 | -COMMA- | denotes | , |
| T16127 | 1210-1211 | -RRB- | denotes | ) |
| T16126 | 1205-1210 | VB | denotes | shown |
| T16125 | 1201-1204 | RB | denotes | not |
| T16124 | 1196-1200 | NN | denotes | data |
| T16123 | 1195-1196 | -LRB- | denotes | ( |
| T16122 | 1185-1194 | JJ | denotes | anti-CD28 |
| T16121 | 1180-1184 | CC | denotes | plus |
| T16120 | 1171-1179 | JJ | denotes | anti-CD3 |
| T16119 | 1166-1170 | IN | denotes | with |
| T16118 | 1154-1165 | NN | denotes | stimulation |
| T16117 | 1151-1153 | IN | denotes | by |
| T16116 | 1141-1150 | VB | denotes | activated |
| T16115 | 1137-1140 | RB | denotes | not |
| T16114 | 1133-1136 | VB | denotes | was |
| T16113 | 1125-1132 | NN | denotes | pathway |
| T16112 | 1120-1124 | NN | denotes | AP-1 |
| T16111 | 1116-1119 | DT | denotes | the |
| T16110 | 1114-1115 | -COMMA- | denotes | , |
| T16109 | 1106-1114 | NN | denotes | contrast |
| T16108 | 1103-1105 | IN | denotes | In |
| T16107 | 1100-1101 | -RRB- | denotes | ) |
| T16106 | 1098-1100 | NN | denotes | 7c |
| T16105 | 1093-1097 | NN | denotes | Fig. |
| T16104 | 1092-1093 | -LRB- | denotes | ( |
| T16103 | 1087-1091 | NN | denotes | time |
| T16102 | 1082-1086 | JJ | denotes | same |
| T16101 | 1078-1081 | DT | denotes | the |
| T16100 | 1075-1077 | IN | denotes | at |
| T16099 | 1070-1074 | NN | denotes | PDTC |
| T16098 | 1066-1069 | CC | denotes | and |
| T16097 | 1057-1065 | NN | denotes | LY294002 |
| T16096 | 1054-1056 | IN | denotes | by |
| T16095 | 1048-1053 | NN | denotes | IκB-α |
| T16094 | 1045-1047 | IN | denotes | of |
| T16093 | 1033-1044 | NN | denotes | degradation |
| T16092 | 1030-1032 | IN | denotes | of |
| T16091 | 1019-1029 | NN | denotes | inhibition |
| T16090 | 1012-1018 | VB | denotes | showed |
| T16089 | 1006-1011 | NN | denotes | IκB-α |
| T16088 | 1002-1005 | IN | denotes | for |
| T16087 | 993-1001 | NN | denotes | blotting |
| T16084 | 980-982 | NN | denotes | 7c |
| T16083 | 975-979 | NN | denotes | Fig. |
| T16082 | 974-975 | -LRB- | denotes | ( |
| T16081 | 965-973 | NN | denotes | promoter |
| T16080 | 959-964 | NN | denotes | IL-17 |
| T16079 | 955-958 | DT | denotes | the |
| T16078 | 952-954 | IN | denotes | in |
| T16077 | 943-951 | NN | denotes | activity |
| T16076 | 931-942 | JJ | denotes | DNA-binding |
| T16075 | 925-930 | NN | denotes | NF-κB |
| T16074 | 919-924 | VB | denotes | block |
| T16073 | 912-918 | NN | denotes | agents |
| T16072 | 907-911 | DT | denotes | Both |
| T16071 | 901-905 | NN | denotes | PDTC |
| T16070 | 897-900 | CC | denotes | and |
| T16069 | 888-896 | NN | denotes | LY294002 |
| T16068 | 883-887 | CC | denotes | both |
| T16067 | 878-882 | IN | denotes | with |
| T16066 | 868-877 | NN | denotes | treatment |
| T16065 | 862-867 | IN | denotes | after |
| T16064 | 853-861 | NN | denotes | activity |
| T16063 | 845-852 | NN | denotes | binding |
| T16062 | 839-844 | NN | denotes | NF-κB |
| T16061 | 835-838 | DT | denotes | the |
| T16060 | 825-834 | VB | denotes | determine |
| T16059 | 822-824 | TO | denotes | to |
| T16058 | 817-821 | NN | denotes | EMSA |
| T16057 | 807-816 | VB | denotes | performed |
| T16056 | 804-806 | PRP | denotes | we |
| T16055 | 802-803 | -COMMA- | denotes | , |
| T16054 | 797-802 | NN | denotes | NF-κB |
| T16053 | 793-796 | CC | denotes | and |
| T16052 | 784-792 | NN | denotes | activity |
| T16051 | 779-783 | NN | denotes | PI3K |
| T16050 | 771-778 | IN | denotes | between |
| T16049 | 766-770 | NN | denotes | link |
| T16048 | 762-765 | DT | denotes | the |
| T16047 | 754-761 | VB | denotes | confirm |
| T16046 | 751-753 | TO | denotes | To |
| T16045 | 748-749 | -RRB- | denotes | ) |
| T16044 | 746-748 | NN | denotes | 7b |
| T16043 | 741-745 | NN | denotes | Fig. |
| T16042 | 740-741 | -LRB- | denotes | ( |
| T16041 | 735-739 | NN | denotes | PBMC |
| T16040 | 732-734 | NN | denotes | RA |
| T16039 | 729-731 | IN | denotes | in |
| T16038 | 724-728 | DT | denotes | that |
| T16037 | 719-723 | IN | denotes | than |
| T16036 | 711-718 | JJ | denotes | intense |
| T16035 | 706-710 | RB | denotes | less |
| T16034 | 702-705 | VB | denotes | was |
| T16033 | 692-701 | NN | denotes | anti-CD28 |
| T16032 | 687-691 | CC | denotes | plus |
| T16031 | 678-686 | NN | denotes | anti-CD3 |
| T16030 | 675-677 | IN | denotes | by |
| T16029 | 664-674 | NN | denotes | activation |
| T16028 | 658-663 | NN | denotes | NF-κB |
| T16027 | 655-657 | IN | denotes | of |
| R8599 | T15910 | T15909 | arg1Of | investigate,To |
| R8600 | T15910 | T15911 | arg1Of | investigate,further |
| R8601 | T15915 | T15910 | arg2Of | pathway,investigate |
| R8602 | T15915 | T15912 | arg1Of | pathway,the |
| R8603 | T15915 | T15913 | arg1Of | pathway,intracellular |
| R8604 | T15915 | T15914 | arg1Of | pathway,signaling |
| R8605 | T15915 | T15916 | arg2Of | pathway,activated |
| R8606 | T15915 | T15930 | arg1Of | pathway,responsible |
| R8607 | T15916 | T15929 | arg1Of | activated,and |
| R8608 | T15918 | T15919 | arg1Of | anti-CD3,plus |
| R8609 | T15919 | T15921 | arg1Of | plus,"," |
| R8610 | T15920 | T15919 | arg2Of | anti-CD28,plus |
| R8611 | T15921 | T15924 | arg1Of | ",","," |
| R8612 | T15923 | T15921 | arg2Of | A,"," |
| R8613 | T15923 | T15922 | arg1Of | A,concanavalin |
| R8614 | T15924 | T15926 | arg1Of | ",",and |
| R8615 | T15925 | T15924 | arg2Of | PHA,"," |
| R8616 | T15926 | T15916 | arg1Of | and,activated |
| R8617 | T15926 | T15917 | arg2Of | and,by |
| R8618 | T15927 | T15926 | arg2Of | IL-15,and |
| R8619 | T15929 | T15928 | arg1Of | and,"," |
| R8620 | T15930 | T15929 | arg2Of | responsible,and |
| R8621 | T15930 | T15931 | arg1Of | responsible,for |
| R8622 | T15932 | T15931 | arg2Of | inducing,for |
| R8623 | T15934 | T15932 | arg2Of | expression,inducing |
| R8624 | T15934 | T15933 | arg1Of | expression,IL-17 |
| R8625 | T15936 | T15937 | arg1Of | we,performed |
| R8626 | T15937 | T15909 | modOf | performed,To |
| R8627 | T15937 | T15935 | arg1Of | performed,"," |
| R8628 | T15941 | T15937 | arg2Of | assay,performed |
| R8629 | T15941 | T15938 | arg1Of | assay,an |
| R8630 | T15941 | T15939 | arg1Of | assay,electrophoretic |
| R8631 | T15941 | T15940 | arg1Of | assay,mobility-shift |
| R8632 | T15941 | T15942 | arg1Of | assay,( |
| R8633 | T15941 | T15945 | arg1Of | assay,of |
| R8634 | T15943 | T15942 | arg2Of | EMSA,( |
| R8635 | T15944 | T15942 | arg3Of | ),( |
| R8636 | T15948 | T15945 | arg2Of | sites,of |
| R8637 | T15948 | T15946 | arg1Of | sites,NF-κB |
| R8638 | T15948 | T15947 | arg1Of | sites,recognition |
| R8639 | T15948 | T15949 | arg1Of | sites,in |
| R8640 | T15951 | T15949 | arg2Of | promoters,in |
| R8641 | T15951 | T15950 | arg1Of | promoters,the |
| R8642 | T15951 | T15952 | arg1Of | promoters,of |
| R8643 | T15953 | T15952 | arg2Of | IL-17,of |
| R8644 | T15955 | T15954 | arg2Of | shown,As |
| R8645 | T15955 | T15956 | arg1Of | shown,in |
| R8646 | T15958 | T15956 | arg2Of | 7a,in |
| R8647 | T15958 | T15957 | arg1Of | 7a,Fig. |
| R8648 | T15961 | T15960 | arg1Of | extracts,nuclear |
| R8649 | T15961 | T15962 | arg1Of | extracts,from |
| R8650 | T15961 | T15974 | arg1Of | extracts,demonstrated |
| R8651 | T15964 | T15962 | arg2Of | PBMC,from |
| R8652 | T15964 | T15963 | arg1Of | PBMC,RA |
| R8653 | T15964 | T15965 | arg2Of | PBMC,stimulated |
| R8654 | T15965 | T15966 | arg1Of | stimulated,with |
| R8655 | T15967 | T15968 | arg1Of | anti-CD3,plus |
| R8656 | T15968 | T15966 | arg2Of | plus,with |
| R8657 | T15968 | T15970 | arg1Of | plus,( |
| R8658 | T15969 | T15968 | arg2Of | anti-CD28,plus |
| R8659 | T15971 | T15970 | arg2Of | lane,( |
| R8660 | T15971 | T15972 | arg1Of | lane,2 |
| R8661 | T15973 | T15970 | arg3Of | ),( |
| R8662 | T15974 | T15954 | arg1Of | demonstrated,As |
| R8663 | T15974 | T15959 | arg1Of | demonstrated,"," |
| R8664 | T15974 | T15982 | arg1Of | demonstrated,in |
| R8665 | T15976 | T15974 | arg2Of | binding,demonstrated |
| R8666 | T15976 | T15975 | arg2Of | binding,increased |
| R8667 | T15976 | T15977 | arg1Of | binding,of |
| R8668 | T15976 | T15979 | arg1Of | binding,to |
| R8669 | T15978 | T15977 | arg2Of | NF-κB,of |
| R8670 | T15981 | T15979 | arg2Of | promoters,to |
| R8671 | T15981 | T15980 | arg1Of | promoters,IL-17 |
| R8672 | T15983 | T15982 | arg2Of | comparison,in |
| R8673 | T15983 | T15984 | arg1Of | comparison,with |
| R8674 | T15985 | T15984 | arg2Of | that,with |
| R8675 | T15985 | T15986 | arg1Of | that,of |
| R8676 | T15987 | T15986 | arg2Of | controls,of |
| R8677 | T15987 | T15988 | arg1Of | controls,( |
| R8678 | T15989 | T15988 | arg2Of | lane,( |
| R8679 | T15989 | T15990 | arg1Of | lane,1 |
| R8680 | T15991 | T15988 | arg3Of | ),( |
| R8681 | T15994 | T15992 | arg1Of | assay,A |
| R8682 | T15994 | T15993 | arg1Of | assay,supershift |
| R8683 | T15994 | T15995 | arg1Of | assay,demonstrated |
| R8684 | T15995 | T16009 | arg1Of | demonstrated,in |
| R8685 | T15997 | T15995 | arg2Of | bands,demonstrated |
| R8686 | T15997 | T15996 | arg2Of | bands,shifted |
| R8687 | T15997 | T15998 | arg1Of | bands,in |
| R8688 | T15999 | T16000 | arg1Of | p65,and |
| R8689 | T16000 | T15998 | arg2Of | and,in |
| R8690 | T16000 | T16002 | arg1Of | and,( |
| R8691 | T16001 | T16000 | arg2Of | p50,and |
| R8692 | T16004 | T16005 | arg1Of | 3,and |
| R8693 | T16005 | T16002 | arg2Of | and,( |
| R8694 | T16005 | T16003 | arg1Of | and,lanes |
| R8695 | T16006 | T16005 | arg2Of | 4,and |
| R8696 | T16007 | T16002 | arg3Of | ),( |
| R8697 | T16009 | T16008 | arg1Of | in,not |
| R8698 | T16010 | T16009 | arg2Of | c-Rel,in |
| R8699 | T16010 | T16011 | arg1Of | c-Rel,( |
| R8700 | T16012 | T16011 | arg2Of | lane,( |
| R8701 | T16012 | T16013 | arg1Of | lane,5 |
| R8702 | T16014 | T16011 | arg3Of | ),( |
| R8703 | T16017 | T16015 | arg2Of | PBMC,In |
| R8704 | T16017 | T16016 | arg1Of | PBMC,normal |
| R8705 | T16020 | T16018 | arg1Of | pattern,the |
| R8706 | T16020 | T16019 | arg1Of | pattern,same |
| R8707 | T16020 | T16021 | arg1Of | pattern,was |
| R8708 | T16020 | T16022 | arg2Of | pattern,observed |
| R8709 | T16022 | T16015 | arg1Of | observed,In |
| R8710 | T16022 | T16021 | arg2Of | observed,was |
| R8711 | T16022 | T16024 | arg1Of | observed,but |
| R8712 | T16024 | T16023 | arg1Of | but,"," |
| R8713 | T16026 | T16025 | arg1Of | degree,the |
| R8714 | T16026 | T16027 | arg1Of | degree,of |
| R8715 | T16026 | T16030 | arg1Of | degree,by |
| R8716 | T16026 | T16034 | arg1Of | degree,was |
| R8717 | T16026 | T16036 | arg1Of | degree,intense |
| R8718 | T16029 | T16027 | arg2Of | activation,of |
| R8719 | T16029 | T16028 | arg1Of | activation,NF-κB |
| R8720 | T16031 | T16032 | arg1Of | anti-CD3,plus |
| R8721 | T16032 | T16030 | arg2Of | plus,by |
| R8722 | T16033 | T16032 | arg2Of | anti-CD28,plus |
| R8723 | T16034 | T16024 | arg2Of | was,but |
| R8724 | T16036 | T16034 | arg2Of | intense,was |
| R8725 | T16036 | T16035 | arg1Of | intense,less |
| R8726 | T16036 | T16037 | arg1Of | intense,than |
| R8727 | T16038 | T16037 | arg2Of | that,than |
| R8728 | T16038 | T16039 | arg1Of | that,in |
| R8729 | T16041 | T16039 | arg2Of | PBMC,in |
| R8730 | T16041 | T16040 | arg1Of | PBMC,RA |
| R8731 | T16041 | T16042 | arg1Of | PBMC,( |
| R8732 | T16044 | T16042 | arg2Of | 7b,( |
| R8733 | T16044 | T16043 | arg1Of | 7b,Fig. |
| R8734 | T16045 | T16042 | arg3Of | ),( |
| R8735 | T16047 | T16046 | arg1Of | confirm,To |
| R8736 | T16049 | T16047 | arg2Of | link,confirm |
| R8737 | T16049 | T16048 | arg1Of | link,the |
| R8738 | T16049 | T16050 | arg1Of | link,between |
| R8739 | T16052 | T16051 | arg1Of | activity,PI3K |
| R8740 | T16052 | T16053 | arg1Of | activity,and |
| R8741 | T16053 | T16050 | arg2Of | and,between |
| R8742 | T16054 | T16053 | arg2Of | NF-κB,and |
| R8743 | T16056 | T16047 | arg1Of | we,confirm |
| R8744 | T16056 | T16057 | arg1Of | we,performed |
| R8745 | T16057 | T16046 | modOf | performed,To |
| R8746 | T16057 | T16055 | arg1Of | performed,"," |
| R8747 | T16058 | T16057 | arg2Of | EMSA,performed |
| R8748 | T16058 | T16059 | modOf | EMSA,to |
| R8749 | T16060 | T16059 | arg1Of | determine,to |
| R8750 | T16060 | T16065 | arg1Of | determine,after |
| R8751 | T16064 | T16060 | arg2Of | activity,determine |
| R8752 | T16064 | T16061 | arg1Of | activity,the |
| R8753 | T16064 | T16062 | arg1Of | activity,NF-κB |
| R8754 | T16064 | T16063 | arg1Of | activity,binding |
| R8755 | T16066 | T16065 | arg2Of | treatment,after |
| R8756 | T16066 | T16067 | arg1Of | treatment,with |
| R8757 | T16069 | T16070 | arg1Of | LY294002,and |
| R8758 | T16070 | T16067 | arg2Of | and,with |
| R8759 | T16070 | T16068 | arg1Of | and,both |
| R8760 | T16071 | T16070 | arg2Of | PDTC,and |
| R8761 | T16073 | T16072 | arg1Of | agents,Both |
| R8762 | T16073 | T16074 | arg1Of | agents,block |
| R8763 | T16077 | T16074 | arg2Of | activity,block |
| R8764 | T16077 | T16075 | arg1Of | activity,NF-κB |
| R8765 | T16077 | T16076 | arg1Of | activity,DNA-binding |
| R8766 | T16077 | T16078 | arg1Of | activity,in |
| R8767 | T16081 | T16078 | arg2Of | promoter,in |
| R8768 | T16081 | T16079 | arg1Of | promoter,the |
| R8769 | T16081 | T16080 | arg1Of | promoter,IL-17 |
| R8770 | T16081 | T16082 | arg1Of | promoter,( |
| R8771 | T16084 | T16082 | arg2Of | 7c,( |
| R8772 | T16084 | T16083 | arg1Of | 7c,Fig. |
| R8773 | T16085 | T16082 | arg3Of | ),( |
| R8774 | T16087 | T16086 | arg1Of | blotting,Western |
| R8775 | T16087 | T16088 | arg1Of | blotting,for |
| R8776 | T16087 | T16090 | arg1Of | blotting,showed |
| R8777 | T16089 | T16088 | arg2Of | IκB-α,for |
| R8778 | T16091 | T16090 | arg2Of | inhibition,showed |
| R8779 | T16091 | T16092 | arg1Of | inhibition,of |
| R8780 | T16093 | T16092 | arg2Of | degradation,of |
| R8781 | T16093 | T16094 | arg1Of | degradation,of |
| R8782 | T16093 | T16096 | arg1Of | degradation,by |
| R8783 | T16093 | T16100 | arg1Of | degradation,at |
| R8784 | T16095 | T16094 | arg2Of | IκB-α,of |
| R8785 | T16097 | T16098 | arg1Of | LY294002,and |
| R8786 | T16098 | T16096 | arg2Of | and,by |
| R8787 | T16099 | T16098 | arg2Of | PDTC,and |
| R8788 | T16103 | T16100 | arg2Of | time,at |
| R8789 | T16103 | T16101 | arg1Of | time,the |
| R8790 | T16103 | T16102 | arg1Of | time,same |
| R8791 | T16103 | T16104 | arg1Of | time,( |
| R8792 | T16106 | T16104 | arg2Of | 7c,( |
| R8793 | T16106 | T16105 | arg1Of | 7c,Fig. |
| R8794 | T16107 | T16104 | arg3Of | ),( |
| R8795 | T16109 | T16108 | arg2Of | contrast,In |
| R8796 | T16113 | T16111 | arg1Of | pathway,the |
| R8797 | T16113 | T16112 | arg1Of | pathway,AP-1 |
| R8798 | T16113 | T16114 | arg1Of | pathway,was |
| R8799 | T16113 | T16116 | arg2Of | pathway,activated |
| R8800 | T16116 | T16108 | arg1Of | activated,In |
| R8801 | T16116 | T16110 | arg1Of | activated,"," |
| R8802 | T16116 | T16114 | arg2Of | activated,was |
| R8803 | T16116 | T16115 | arg1Of | activated,not |
| R8804 | T16116 | T16128 | arg1Of | activated,"," |
| R8805 | T16116 | T16129 | modOf | activated,demonstrating |
| R8806 | T16118 | T16116 | arg1Of | stimulation,activated |
| R8807 | T16118 | T16117 | arg2Of | stimulation,by |
| R8808 | T16118 | T16119 | arg1Of | stimulation,with |
| R8809 | T16120 | T16121 | arg1Of | anti-CD3,plus |
| R8810 | T16122 | T16121 | arg2Of | anti-CD28,plus |
| R8811 | T16124 | T16119 | arg2Of | data,with |
| R8812 | T16124 | T16120 | arg1Of | data,anti-CD3 |
| R8813 | T16124 | T16122 | arg1Of | data,anti-CD28 |
| R8814 | T16124 | T16123 | arg2Of | data,( |
| R8815 | T16124 | T16126 | arg2Of | data,shown |
| R8816 | T16126 | T16125 | arg1Of | shown,not |
| R8817 | T16127 | T16123 | arg3Of | ),( |
| R8818 | T16131 | T16132 | arg1Of | NF-κB,is |
| R8819 | T16132 | T16129 | arg2Of | is,demonstrating |
| R8820 | T16132 | T16130 | arg1Of | is,that |
| R8821 | T16137 | T16132 | arg2Of | pathway,is |
| R8822 | T16137 | T16133 | arg1Of | pathway,the |
| R8823 | T16137 | T16134 | arg1Of | pathway,main |
| R8824 | T16137 | T16135 | arg1Of | pathway,intracellular |
| R8825 | T16137 | T16136 | arg1Of | pathway,signaling |
| R8826 | T16137 | T16138 | arg1Of | pathway,in |
| R8827 | T16137 | T16141 | arg1Of | pathway,by |
| R8828 | T16140 | T16138 | arg2Of | production,in |
| R8829 | T16140 | T16139 | arg1Of | production,IL-17 |
| R8830 | T16143 | T16141 | arg2Of | PBMC,by |
| R8831 | T16143 | T16142 | arg2Of | PBMC,activated |
| R8832 | T16143 | T16144 | arg1Of | PBMC,from |
| R8833 | T16145 | T16144 | arg2Of | patients,from |
| R8834 | T16145 | T16146 | arg1Of | patients,with |
| R8835 | T16147 | T16146 | arg2Of | RA,with |
bionlp-st-ge-2016-test-proteins
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16167 | 1285-1290 | Protein | denotes | IL-17 |
| T16166 | 1190-1194 | Protein | denotes | CD28 |
| T16165 | 1120-1124 | Protein | denotes | AP-1 |
| T16164 | 1048-1053 | Protein | denotes | IκB-α |
| T16163 | 1006-1011 | Protein | denotes | IκB-α |
| T16162 | 959-964 | Protein | denotes | IL-17 |
| T16161 | 697-701 | Protein | denotes | CD28 |
| T16160 | 578-583 | Protein | denotes | c-Rel |
| T16159 | 551-554 | Protein | denotes | p50 |
| T16158 | 543-546 | Protein | denotes | p65 |
| T16157 | 432-437 | Protein | denotes | IL-17 |
| T16156 | 375-379 | Protein | denotes | CD28 |
| T16155 | 282-287 | Protein | denotes | IL-17 |
| T16154 | 157-162 | Protein | denotes | IL-17 |
| T16153 | 121-126 | Protein | denotes | IL-15 |
| T16152 | 113-116 | Protein | denotes | PHA |
| T16151 | 91-95 | Protein | denotes | CD28 |
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16313 | 578-583 | http://www.uniprot.org/uniprot/Q04864 | denotes | c-Rel |
| T16312 | 551-554 | http://www.uniprot.org/uniprot/P19838 | denotes | p50 |
| T16311 | 543-546 | http://www.uniprot.org/uniprot/P21579 | denotes | p65 |
| T16310 | 543-546 | http://www.uniprot.org/uniprot/Q04206 | denotes | p65 |
| T16309 | 121-126 | http://www.uniprot.org/uniprot/P40933 | denotes | IL-15 |
| T16308 | 1190-1194 | http://www.uniprot.org/uniprot/P10747 | denotes | CD28 |
| T16307 | 697-701 | http://www.uniprot.org/uniprot/P10747 | denotes | CD28 |
| T16306 | 375-379 | http://www.uniprot.org/uniprot/P10747 | denotes | CD28 |
| T16305 | 91-95 | http://www.uniprot.org/uniprot/P10747 | denotes | CD28 |
| T16304 | 1176-1179 | http://www.uniprot.org/uniprot/P09693 | denotes | CD3 |
| T16303 | 683-686 | http://www.uniprot.org/uniprot/P09693 | denotes | CD3 |
| T16302 | 361-364 | http://www.uniprot.org/uniprot/P09693 | denotes | CD3 |
| T16301 | 77-80 | http://www.uniprot.org/uniprot/P09693 | denotes | CD3 |
| T16300 | 1176-1179 | http://www.uniprot.org/uniprot/P07766 | denotes | CD3 |
| T16299 | 683-686 | http://www.uniprot.org/uniprot/P07766 | denotes | CD3 |
| T16298 | 361-364 | http://www.uniprot.org/uniprot/P07766 | denotes | CD3 |
| T16297 | 77-80 | http://www.uniprot.org/uniprot/P07766 | denotes | CD3 |
| T16296 | 1176-1179 | http://www.uniprot.org/uniprot/P04234 | denotes | CD3 |
| T16295 | 683-686 | http://www.uniprot.org/uniprot/P04234 | denotes | CD3 |
| T16294 | 361-364 | http://www.uniprot.org/uniprot/P04234 | denotes | CD3 |
| T16293 | 77-80 | http://www.uniprot.org/uniprot/P04234 | denotes | CD3 |
| T16292 | 1176-1179 | http://www.uniprot.org/uniprot/P20963 | denotes | CD3 |
| T16291 | 683-686 | http://www.uniprot.org/uniprot/P20963 | denotes | CD3 |
| T16290 | 361-364 | http://www.uniprot.org/uniprot/P20963 | denotes | CD3 |
| T16289 | 77-80 | http://www.uniprot.org/uniprot/P20963 | denotes | CD3 |
| T16288 | 1285-1290 | http://www.uniprot.org/uniprot/Q16552 | denotes | IL-17 |
| T16287 | 959-964 | http://www.uniprot.org/uniprot/Q16552 | denotes | IL-17 |
| T16286 | 432-437 | http://www.uniprot.org/uniprot/Q16552 | denotes | IL-17 |
| T16285 | 282-287 | http://www.uniprot.org/uniprot/Q16552 | denotes | IL-17 |
| T16284 | 157-162 | http://www.uniprot.org/uniprot/Q16552 | denotes | IL-17 |
| T16282 | 1120-1124 | http://www.uniprot.org/uniprot/P05412 | denotes | AP-1 |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T15854 | 1288-1314 | http://purl.obolibrary.org/obo/GO_0032740 | denotes | 17 production by activated |
| T15853 | 1285-1301 | http://purl.obolibrary.org/obo/GO_0032620 | denotes | IL-17 production |
| T15852 | 1285-1301 | http://purl.obolibrary.org/obo/GO_0032660 | denotes | IL-17 production |
| T15851 | 1033-1044 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
| T15850 | 779-783 | http://purl.obolibrary.org/obo/GO_0016303 | denotes | PI3K |
| T15849 | 658-674 | http://purl.obolibrary.org/obo/GO_0051092 | denotes | NF-κB activation |
| T15848 | 41-68 | http://purl.obolibrary.org/obo/GO_1903265 | denotes | signaling pathway activated |
| T15847 | 41-68 | http://purl.obolibrary.org/obo/GO_1902843 | denotes | signaling pathway activated |
| T15846 | 41-68 | http://purl.obolibrary.org/obo/GO_1902046 | denotes | signaling pathway activated |
| T15845 | 41-68 | http://purl.obolibrary.org/obo/GO_1900236 | denotes | signaling pathway activated |
| T15844 | 41-68 | http://purl.obolibrary.org/obo/GO_0038084 | denotes | signaling pathway activated |
| T15843 | 41-68 | http://purl.obolibrary.org/obo/GO_0009873 | denotes | signaling pathway activated |
| T15842 | 41-68 | http://purl.obolibrary.org/obo/GO_1902204 | denotes | signaling pathway activated |
| T15841 | 41-68 | http://purl.obolibrary.org/obo/GO_1901186 | denotes | signaling pathway activated |
| T15840 | 41-68 | http://purl.obolibrary.org/obo/GO_0033211 | denotes | signaling pathway activated |
| T15839 | 41-68 | http://purl.obolibrary.org/obo/GO_0009736 | denotes | signaling pathway activated |
| T15838 | 1264-1281 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathway |
| T15837 | 41-58 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathway |
| T15836 | 1264-1273 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T15835 | 41-50 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T15834 | 27-68 | http://purl.obolibrary.org/obo/GO_1902533 | denotes | intracellular signaling pathway activated |
| T15833 | 1250-1281 | http://purl.obolibrary.org/obo/GO_1902531 | denotes | intracellular signaling pathway |
| T15832 | 27-58 | http://purl.obolibrary.org/obo/GO_1902531 | denotes | intracellular signaling pathway |
| T15831 | 1250-1281 | http://purl.obolibrary.org/obo/GO_1902532 | denotes | intracellular signaling pathway |
| T15830 | 27-58 | http://purl.obolibrary.org/obo/GO_1902532 | denotes | intracellular signaling pathway |
| T15829 | 1250-1281 | http://purl.obolibrary.org/obo/GO_0035556 | denotes | intracellular signaling pathway |
| T15828 | 27-58 | http://purl.obolibrary.org/obo/GO_0035556 | denotes | intracellular signaling pathway |
| T15827 | 1250-1281 | http://purl.obolibrary.org/obo/GO_0030522 | denotes | intracellular signaling pathway |
| T15826 | 27-58 | http://purl.obolibrary.org/obo/GO_0030522 | denotes | intracellular signaling pathway |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16181 | 931-942 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA-binding |
| T16180 | 779-783 | http://purl.obolibrary.org/obo/GO_0016303 | denotes | PI3K |
| T16179 | 839-852 | http://purl.obolibrary.org/obo/GO_0051059 | denotes | NF-κB binding |
| T16178 | 412-428 | http://purl.obolibrary.org/obo/GO_0051059 | denotes | binding of NF-κB |
| T16177 | 935-942 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T16176 | 845-852 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T16175 | 412-419 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T16174 | 121-126 | http://purl.obolibrary.org/obo/GO_0016170 | denotes | IL-15 |
| T16173 | 1285-1290 | http://purl.obolibrary.org/obo/GO_0030367 | denotes | IL-17 |
| T16172 | 959-964 | http://purl.obolibrary.org/obo/GO_0030367 | denotes | IL-17 |
| T16171 | 432-437 | http://purl.obolibrary.org/obo/GO_0030367 | denotes | IL-17 |
| T16170 | 282-287 | http://purl.obolibrary.org/obo/GO_0030367 | denotes | IL-17 |
| T16169 | 157-162 | http://purl.obolibrary.org/obo/GO_0030367 | denotes | IL-17 |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16183 | 1250-1263 | http://purl.obolibrary.org/obo/GO_0005622 | denotes | intracellular |
| T16182 | 27-40 | http://purl.obolibrary.org/obo/GO_0005622 | denotes | intracellular |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T15825 | 1103-1342 | Sentence | denotes | In contrast, the AP-1 pathway was not activated by stimulation with anti-CD3 plus anti-CD28 (data not shown), demonstrating that NF-κB is the main intracellular signaling pathway in IL-17 production by activated PBMC from patients with RA. |
| T15824 | 985-1102 | Sentence | denotes | Western blotting for IκB-α showed inhibition of degradation of IκB-α by LY294002 and PDTC at the same time (Fig. 7c). |
| T15823 | 907-984 | Sentence | denotes | Both agents block NF-κB DNA-binding activity in the IL-17 promoter (Fig. 7c). |
| T15822 | 751-906 | Sentence | denotes | To confirm the link between PI3K activity and NF-κB, we performed EMSA to determine the NF-κB binding activity after treatment with both LY294002 and PDTC. |
| T15821 | 594-750 | Sentence | denotes | In normal PBMC the same pattern was observed, but the degree of NF-κB activation by anti-CD3 plus anti-CD28 was less intense than that in RA PBMC (Fig. 7b). |
| T15820 | 494-593 | Sentence | denotes | A supershift assay demonstrated shifted bands in p65 and p50 (lanes 3 and 4) not in c-Rel (lane 5). |
| T15819 | 289-493 | Sentence | denotes | As shown in Fig. 7a, nuclear extracts from RA PBMC stimulated with anti-CD3 plus anti-CD28 (lane 2) demonstrated increased binding of NF-κB to IL-17 promoters in comparison with that of controls (lane 1). |
| T15818 | 0-288 | Sentence | denotes | To investigate further the intracellular signaling pathway activated by anti-CD3 plus anti-CD28, concanavalin A, PHA and IL-15, and responsible for inducing IL-17 expression, we performed an electrophoretic mobility-shift assay (EMSA) of NF-κB recognition sites in the promoters of IL-17. |
| T148 | 0-288 | Sentence | denotes | To investigate further the intracellular signaling pathway activated by anti-CD3 plus anti-CD28, concanavalin A, PHA and IL-15, and responsible for inducing IL-17 expression, we performed an electrophoretic mobility-shift assay (EMSA) of NF-κB recognition sites in the promoters of IL-17. |
| T149 | 289-493 | Sentence | denotes | As shown in Fig. 7a, nuclear extracts from RA PBMC stimulated with anti-CD3 plus anti-CD28 (lane 2) demonstrated increased binding of NF-κB to IL-17 promoters in comparison with that of controls (lane 1). |
| T150 | 494-593 | Sentence | denotes | A supershift assay demonstrated shifted bands in p65 and p50 (lanes 3 and 4) not in c-Rel (lane 5). |
| T151 | 594-750 | Sentence | denotes | In normal PBMC the same pattern was observed, but the degree of NF-κB activation by anti-CD3 plus anti-CD28 was less intense than that in RA PBMC (Fig. 7b). |
| T152 | 751-906 | Sentence | denotes | To confirm the link between PI3K activity and NF-κB, we performed EMSA to determine the NF-κB binding activity after treatment with both LY294002 and PDTC. |
| T153 | 907-984 | Sentence | denotes | Both agents block NF-κB DNA-binding activity in the IL-17 promoter (Fig. 7c). |
| T154 | 985-1102 | Sentence | denotes | Western blotting for IκB-α showed inhibition of degradation of IκB-α by LY294002 and PDTC at the same time (Fig. 7c). |
| T155 | 1103-1342 | Sentence | denotes | In contrast, the AP-1 pathway was not activated by stimulation with anti-CD3 plus anti-CD28 (data not shown), demonstrating that NF-κB is the main intracellular signaling pathway in IL-17 production by activated PBMC from patients with RA. |
simple1
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16280 | 1285-1290 | Protein | denotes | IL-17 |
| T16279 | 1190-1194 | Protein | denotes | CD28 |
| T16278 | 1120-1124 | Protein | denotes | AP-1 |
| T16277 | 1048-1053 | Protein | denotes | IκB-α |
| T16276 | 1006-1011 | Protein | denotes | IκB-α |
| T16275 | 959-964 | Protein | denotes | IL-17 |
| T16274 | 697-701 | Protein | denotes | CD28 |
| T16273 | 578-583 | Protein | denotes | c-Rel |
| T16272 | 551-554 | Protein | denotes | p50 |
| T16271 | 543-546 | Protein | denotes | p65 |
| T16270 | 432-437 | Protein | denotes | IL-17 |
| T16269 | 375-379 | Protein | denotes | CD28 |
| T16268 | 282-287 | Protein | denotes | IL-17 |
| T16267 | 157-162 | Protein | denotes | IL-17 |
| T16266 | 121-126 | Protein | denotes | IL-15 |
| T16265 | 113-116 | Protein | denotes | PHA |
| T16264 | 91-95 | Protein | denotes | CD28 |
DLUT931
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16373 | 1305-1314 | Positive_regulation | denotes | activated |
| T16372 | 1291-1301 | Gene_expression | denotes | production |
| T16371 | 1141-1150 | Positive_regulation | denotes | activated |
| T16370 | 1019-1029 | Negative_regulation | denotes | inhibition |
| T16369 | 1033-1044 | Protein_catabolism | denotes | degradation |
| T16368 | 931-942 | Binding | denotes | DNA-binding |
| T16367 | 402-411 | Positive_regulation | denotes | increased |
| T16366 | 412-419 | Binding | denotes | binding |
| T16365 | 148-156 | Positive_regulation | denotes | inducing |
| T16364 | 163-173 | Gene_expression | denotes | expression |
| T16362 | 1285-1290 | Protein | denotes | IL-17 |
| T16361 | 1190-1194 | Protein | denotes | CD28 |
| T16360 | 1120-1124 | Protein | denotes | AP-1 |
| T16359 | 1048-1053 | Protein | denotes | IκB-α |
| T16358 | 1006-1011 | Protein | denotes | IκB-α |
| T16357 | 959-964 | Protein | denotes | IL-17 |
| T16356 | 697-701 | Protein | denotes | CD28 |
| T16355 | 578-583 | Protein | denotes | c-Rel |
| T16354 | 551-554 | Protein | denotes | p50 |
| T16353 | 543-546 | Protein | denotes | p65 |
| T16352 | 375-379 | Protein | denotes | CD28 |
| T16351 | 432-437 | Protein | denotes | IL-17 |
| T16350 | 282-287 | Protein | denotes | IL-17 |
| T16349 | 157-162 | Protein | denotes | IL-17 |
| T16348 | 121-126 | Protein | denotes | IL-15 |
| T16347 | 113-116 | Protein | denotes | PHA |
| T16346 | 91-95 | Protein | denotes | CD28 |
| R8872 | T16349 | T16364 | themeOf | IL-17,expression |
| R8873 | T16351 | T16366 | themeOf | IL-17,binding |
| R8874 | T16357 | T16368 | themeOf | IL-17,DNA-binding |
| R8875 | T16359 | T16369 | themeOf | IκB-α,degradation |
| R8876 | T16360 | T16371 | themeOf | AP-1,activated |
| R8877 | T16362 | T16372 | themeOf | IL-17,production |
| R8878 | T16364 | T16365 | themeOf | expression,inducing |
| R8879 | T16366 | T16367 | themeOf | binding,increased |
| R8880 | T16369 | T16370 | themeOf | degradation,inhibition |
| R8881 | T16372 | T16373 | themeOf | production,activated |
bionlp-st-ge-2016-test-ihmc
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16780 | 658-701 | Positive_regulation | denotes | NF-κB activation by anti-CD3 plus anti-CD28 |
| T16779 | 658-701 | Positive_regulation | denotes | NF-κB activation by anti-CD3 plus anti-CD28 |
| T16778 | 1285-1341 | Gene_expression | denotes | IL-17 production by activated PBMC from patients with RA |
| T16777 | 1030-1053 | Protein_catabolism | denotes | of degradation of IκB-α |
| T16774 | 1012-1065 | Negative_regulation | denotes | showed inhibition of degradation of IκB-α by LY294002 |
| T16773 | 157-174 | Gene_expression | denotes | IL-17 expression, |
| T16772 | 402-447 | Positive_regulation | denotes | increased binding of NF-κB to IL-17 promoters |
| T16771 | 310-447 | Binding | denotes | nuclear extracts from RA PBMC stimulated with anti-CD3 plus anti-CD28 (lane 2) demonstrated increased binding of NF-κB to IL-17 promoters |
| T16770 | 432-437 | Protein | denotes | IL-17 |
| T16769 | 959-964 | Protein | denotes | IL-17 |
| T16768 | 238-243 | Protein | denotes | NF-κB |
| T16767 | 955-983 | Entity | denotes | the IL-17 promoter (Fig. 7c) |
| T16766 | 121-126 | Protein | denotes | IL-15 |
| T16765 | 238-261 | Entity | denotes | NF-κB recognition sites |
| T16764 | 157-162 | Protein | denotes | IL-17 |
| T16736 | 1227-1237 | Protein | denotes | that NF-κB |
| T16735 | 332-334 | Protein | denotes | RA |
| T16734 | 578-592 | Protein | denotes | c-Rel (lane 5) |
| T16733 | 97-111 | Protein | denotes | concanavalin A |
| T16732 | 23-40 | Entity | denotes | the intracellular |
| T16731 | 1116-1132 | Protein | denotes | the AP-1 pathway |
| T16730 | 551-554 | Protein | denotes | p50 |
| T16729 | 420-428 | Protein | denotes | of NF-κB |
| T16728 | 86-127 | Protein | denotes | anti-CD28, concanavalin A, PHA and IL-15, |
| T16727 | 429-447 | Entity | denotes | to IL-17 promoters |
| T16726 | 301-304 | Protein | denotes | Fig |
| T16725 | 1006-1011 | Protein | denotes | IκB-α |
| T16724 | 678-686 | Protein | denotes | anti-CD3 |
| T16723 | 597-608 | Entity | denotes | normal PBMC |
| T16722 | 1171-1179 | Protein | denotes | anti-CD3 |
| T16721 | 370-388 | Protein | denotes | anti-CD28 (lane 2) |
| T16720 | 113-116 | Protein | denotes | PHA |
| T16719 | 925-930 | Protein | denotes | NF-κB |
| T16718 | 888-896 | Entity | denotes | LY294002 |
| T16763 | 1250-1263 | Entity | denotes | intracellular |
| T16762 | 72-80 | Protein | denotes | anti-CD3 |
| T16761 | 658-663 | Protein | denotes | NF-κB |
| T16757 | 282-287 | Protein | denotes | IL-17 |
| T16756 | 1302-1319 | Entity | denotes | by activated PBMC |
| T16754 | 543-546 | Protein | denotes | p65 |
| T16753 | 1093-1096 | Protein | denotes | Fig |
| T16752 | 332-388 | Entity | denotes | RA PBMC stimulated with anti-CD3 plus anti-CD28 (lane 2) |
| T16751 | 265-287 | Entity | denotes | the promoters of IL-17 |
| T16750 | 1185-1194 | Protein | denotes | anti-CD28 |
| T16749 | 732-734 | Protein | denotes | RA |
| T16748 | 356-364 | Protein | denotes | anti-CD3 |
| T16747 | 1339-1341 | Protein | denotes | RA |
| T16746 | 310-388 | Entity | denotes | nuclear extracts from RA PBMC stimulated with anti-CD3 plus anti-CD28 (lane 2) |
| T16744 | 1285-1290 | Protein | denotes | IL-17 |
| T16743 | 732-739 | Entity | denotes | RA PBMC |
| T16742 | 1045-1053 | Protein | denotes | of IκB-α |
| T16741 | 797-802 | Protein | denotes | NF-κB |
| T16740 | 741-744 | Protein | denotes | Fig |
| T16739 | 692-701 | Protein | denotes | anti-CD28 |
| T16738 | 779-783 | Protein | denotes | PI3K |
| T16737 | 1054-1065 | Entity | denotes | by LY294002 |
| R9175 | T16724 | T16779 | causeOf | anti-CD3,NF-κB activation by anti-CD3 plus anti-CD28 |
| R9176 | T16727 | T16770 | partOf | to IL-17 promoters,IL-17 |
| R9177 | T16727 | T16771 | themeOf | to IL-17 promoters,nuclear extracts from RA PBMC stimulated with anti-CD3 plus anti-CD28 (lane 2) demonstrated increased binding of NF-κB to IL-17 promoters |
| R9178 | T16729 | T16771 | themeOf | of NF-κB,nuclear extracts from RA PBMC stimulated with anti-CD3 plus anti-CD28 (lane 2) demonstrated increased binding of NF-κB to IL-17 promoters |
| R9179 | T16737 | T16774 | causeOf | by LY294002,showed inhibition of degradation of IκB-α by LY294002 |
| R9180 | T16739 | T16780 | causeOf | anti-CD28,NF-κB activation by anti-CD3 plus anti-CD28 |
| R9181 | T16742 | T16777 | themeOf | of IκB-α,of degradation of IκB-α |
| R9182 | T16744 | T16778 | themeOf | IL-17,IL-17 production by activated PBMC from patients with RA |
| R9185 | T16761 | T16779 | themeOf | NF-κB,NF-κB activation by anti-CD3 plus anti-CD28 |
| R9186 | T16761 | T16780 | themeOf | NF-κB,NF-κB activation by anti-CD3 plus anti-CD28 |
| R9187 | T16764 | T16773 | themeOf | IL-17,"IL-17 expression," |
| R9188 | T16767 | T16769 | partOf | the IL-17 promoter (Fig. 7c),IL-17 |
| R9189 | T16771 | T16772 | themeOf | nuclear extracts from RA PBMC stimulated with anti-CD3 plus anti-CD28 (lane 2) demonstrated increased binding of NF-κB to IL-17 promoters,increased binding of NF-κB to IL-17 promoters |
| R9190 | T16777 | T16774 | themeOf | of degradation of IκB-α,showed inhibition of degradation of IκB-α by LY294002 |
bionlp-st-ge-2016-spacy-parsed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16660 | 1341-1342 | . | denotes | . |
| T16659 | 1339-1341 | NNP | denotes | RA |
| T16658 | 1334-1338 | IN | denotes | with |
| T16657 | 1325-1333 | NNS | denotes | patients |
| T16656 | 1320-1324 | IN | denotes | from |
| T16655 | 1315-1319 | NNP | denotes | PBMC |
| T16654 | 1305-1314 | VBN | denotes | activated |
| T16653 | 1302-1304 | IN | denotes | by |
| T16652 | 1291-1301 | NN | denotes | production |
| T16651 | 1285-1290 | JJ | denotes | IL-17 |
| T16650 | 1282-1284 | IN | denotes | in |
| T16649 | 1274-1281 | NN | denotes | pathway |
| T16648 | 1264-1273 | VBG | denotes | signaling |
| T16647 | 1250-1263 | JJ | denotes | intracellular |
| T16646 | 1245-1249 | JJ | denotes | main |
| T16645 | 1241-1244 | DT | denotes | the |
| T16644 | 1238-1240 | VBZ | denotes | is |
| T16643 | 1232-1237 | NNP | denotes | NF-κB |
| T16620 | 1103-1105 | IN | denotes | In |
| T16619 | 1101-1102 | . | denotes | . |
| T16618 | 1100-1101 | -RRB- | denotes | ) |
| T16617 | 1098-1100 | CD | denotes | 7c |
| T16616 | 1093-1097 | NNP | denotes | Fig. |
| T16615 | 1092-1093 | -LRB- | denotes | ( |
| T16614 | 1087-1091 | NN | denotes | time |
| T16613 | 1082-1086 | JJ | denotes | same |
| T16612 | 1078-1081 | DT | denotes | the |
| T16611 | 1075-1077 | IN | denotes | at |
| T16610 | 1070-1074 | NNP | denotes | PDTC |
| T16609 | 1066-1069 | CC | denotes | and |
| T16608 | 1057-1065 | NNP | denotes | LY294002 |
| T16607 | 1054-1056 | IN | denotes | by |
| T16606 | 1048-1053 | JJ | denotes | IκB-α |
| T16605 | 1045-1047 | IN | denotes | of |
| T16604 | 1033-1044 | NN | denotes | degradation |
| T16603 | 1030-1032 | IN | denotes | of |
| T16602 | 1019-1029 | NN | denotes | inhibition |
| T16601 | 1012-1018 | VBD | denotes | showed |
| T16600 | 1006-1011 | JJ | denotes | IκB-α |
| T16599 | 1002-1005 | IN | denotes | for |
| T16598 | 993-1001 | VBG | denotes | blotting |
| T16597 | 985-992 | JJ | denotes | Western |
| T16596 | 983-984 | . | denotes | . |
| T16595 | 982-983 | -RRB- | denotes | ) |
| T16594 | 980-982 | CD | denotes | 7c |
| T16593 | 975-979 | NNP | denotes | Fig. |
| T16592 | 974-975 | -LRB- | denotes | ( |
| T16591 | 965-973 | NN | denotes | promoter |
| T16590 | 959-964 | NNP | denotes | IL-17 |
| T16589 | 955-958 | DT | denotes | the |
| T16588 | 952-954 | IN | denotes | in |
| T16587 | 943-951 | NN | denotes | activity |
| T16586 | 931-942 | JJ | denotes | DNA-binding |
| T16585 | 925-930 | NNP | denotes | NF-κB |
| T16584 | 919-924 | NN | denotes | block |
| T16583 | 912-918 | NNS | denotes | agents |
| T16582 | 907-911 | DT | denotes | Both |
| T16581 | 905-906 | . | denotes | . |
| T16580 | 901-905 | NNP | denotes | PDTC |
| T16579 | 897-900 | CC | denotes | and |
| T16578 | 888-896 | CD | denotes | LY294002 |
| T16577 | 883-887 | DT | denotes | both |
| T16576 | 878-882 | IN | denotes | with |
| T16575 | 868-877 | NN | denotes | treatment |
| T16574 | 862-867 | IN | denotes | after |
| T16573 | 853-861 | NN | denotes | activity |
| T16572 | 845-852 | JJ | denotes | binding |
| T16571 | 839-844 | JJ | denotes | NF-κB |
| T16570 | 835-838 | DT | denotes | the |
| T16569 | 825-834 | VB | denotes | determine |
| T16568 | 822-824 | TO | denotes | to |
| T16567 | 817-821 | NNP | denotes | EMSA |
| T16566 | 807-816 | VBD | denotes | performed |
| T16565 | 804-806 | PRP | denotes | we |
| T16564 | 802-803 | , | denotes | , |
| T16563 | 797-802 | NN | denotes | NF-κB |
| T16562 | 793-796 | CC | denotes | and |
| T16561 | 784-792 | NN | denotes | activity |
| T16560 | 779-783 | JJ | denotes | PI3K |
| T16559 | 771-778 | IN | denotes | between |
| T16558 | 766-770 | NN | denotes | link |
| T16557 | 762-765 | DT | denotes | the |
| T16556 | 754-761 | VB | denotes | confirm |
| T16555 | 751-753 | TO | denotes | To |
| T16554 | 749-750 | . | denotes | . |
| T16553 | 748-749 | -RRB- | denotes | ) |
| T16552 | 746-748 | CD | denotes | 7b |
| T16551 | 741-745 | NNP | denotes | Fig. |
| T16550 | 740-741 | -LRB- | denotes | ( |
| T16549 | 735-739 | NNP | denotes | PBMC |
| T16548 | 732-734 | NNP | denotes | RA |
| T16547 | 729-731 | IN | denotes | in |
| T16546 | 724-728 | DT | denotes | that |
| T16545 | 719-723 | IN | denotes | than |
| T16544 | 711-718 | JJ | denotes | intense |
| T16543 | 706-710 | JJR | denotes | less |
| T16542 | 702-705 | VBD | denotes | was |
| T16541 | 692-701 | JJ | denotes | anti-CD28 |
| T16540 | 687-691 | CC | denotes | plus |
| T16539 | 678-686 | JJ | denotes | anti-CD3 |
| T16538 | 675-677 | IN | denotes | by |
| T16537 | 664-674 | NN | denotes | activation |
| T16536 | 658-663 | JJ | denotes | NF-κB |
| T16535 | 655-657 | IN | denotes | of |
| T16534 | 648-654 | NN | denotes | degree |
| T16533 | 644-647 | DT | denotes | the |
| T16532 | 640-643 | CC | denotes | but |
| T16531 | 638-639 | , | denotes | , |
| T16530 | 630-638 | VBN | denotes | observed |
| T16529 | 626-629 | VBD | denotes | was |
| T16528 | 618-625 | NN | denotes | pattern |
| T16527 | 613-617 | JJ | denotes | same |
| T16526 | 609-612 | DT | denotes | the |
| T16525 | 604-608 | NNP | denotes | PBMC |
| T16524 | 597-603 | JJ | denotes | normal |
| T16523 | 594-596 | IN | denotes | In |
| T16522 | 592-593 | . | denotes | . |
| T16521 | 591-592 | -RRB- | denotes | ) |
| T16520 | 590-591 | CD | denotes | 5 |
| T16519 | 585-589 | NN | denotes | lane |
| T16518 | 584-585 | -LRB- | denotes | ( |
| T16517 | 578-583 | NNP | denotes | c-Rel |
| T16516 | 575-577 | IN | denotes | in |
| T16515 | 571-574 | RB | denotes | not |
| T16514 | 569-570 | -RRB- | denotes | ) |
| T16513 | 568-569 | CD | denotes | 4 |
| T16512 | 564-567 | CC | denotes | and |
| T16511 | 562-563 | CD | denotes | 3 |
| T16510 | 556-561 | NNS | denotes | lanes |
| T16509 | 555-556 | -LRB- | denotes | ( |
| T16508 | 551-554 | CD | denotes | p50 |
| T16507 | 547-550 | CC | denotes | and |
| T16506 | 543-546 | CD | denotes | p65 |
| T16505 | 540-542 | IN | denotes | in |
| T16504 | 534-539 | NNS | denotes | bands |
| T16503 | 526-533 | VBN | denotes | shifted |
| T16502 | 513-525 | VBD | denotes | demonstrated |
| T16501 | 507-512 | NN | denotes | assay |
| T16500 | 496-506 | NN | denotes | supershift |
| T16499 | 494-495 | DT | denotes | A |
| T16498 | 492-493 | . | denotes | . |
| T16497 | 491-492 | -RRB- | denotes | ) |
| T16496 | 490-491 | CD | denotes | 1 |
| T16495 | 485-489 | NN | denotes | lane |
| T16494 | 484-485 | -LRB- | denotes | ( |
| T16493 | 475-483 | NNS | denotes | controls |
| T16492 | 472-474 | IN | denotes | of |
| T16491 | 467-471 | DT | denotes | that |
| T16490 | 462-466 | IN | denotes | with |
| T16489 | 451-461 | NN | denotes | comparison |
| T16488 | 448-450 | IN | denotes | in |
| T16487 | 438-447 | NNS | denotes | promoters |
| T16486 | 432-437 | NNP | denotes | IL-17 |
| T16485 | 429-431 | TO | denotes | to |
| T16484 | 423-428 | NN | denotes | NF-κB |
| T16483 | 420-422 | IN | denotes | of |
| T16482 | 412-419 | JJ | denotes | binding |
| T16481 | 402-411 | VBN | denotes | increased |
| T16480 | 389-401 | VBD | denotes | demonstrated |
| T16479 | 387-388 | -RRB- | denotes | ) |
| T16478 | 386-387 | CD | denotes | 2 |
| T16477 | 381-385 | NN | denotes | lane |
| T16476 | 380-381 | -LRB- | denotes | ( |
| T16475 | 370-379 | JJ | denotes | anti-CD28 |
| T16474 | 365-369 | CC | denotes | plus |
| T16473 | 356-364 | JJ | denotes | anti-CD3 |
| T16472 | 351-355 | IN | denotes | with |
| T16471 | 340-350 | VBD | denotes | stimulated |
| T16470 | 335-339 | NNP | denotes | PBMC |
| T16469 | 332-334 | NNP | denotes | RA |
| T16468 | 327-331 | IN | denotes | from |
| T16467 | 318-326 | NNS | denotes | extracts |
| T16466 | 310-317 | JJ | denotes | nuclear |
| T16465 | 308-309 | , | denotes | , |
| T16464 | 306-308 | CD | denotes | 7a |
| T16463 | 301-305 | NNP | denotes | Fig. |
| T16462 | 298-300 | IN | denotes | in |
| T16461 | 292-297 | VBN | denotes | shown |
| T16460 | 289-291 | IN | denotes | As |
| T16459 | 287-288 | . | denotes | . |
| T16458 | 282-287 | NNP | denotes | IL-17 |
| T16457 | 279-281 | IN | denotes | of |
| T16456 | 269-278 | NNS | denotes | promoters |
| T16455 | 265-268 | DT | denotes | the |
| T16454 | 262-264 | IN | denotes | in |
| T16453 | 256-261 | NNS | denotes | sites |
| T16452 | 244-255 | NN | denotes | recognition |
| T16451 | 238-243 | NN | denotes | NF-κB |
| T16450 | 235-237 | IN | denotes | of |
| T16449 | 233-234 | -RRB- | denotes | ) |
| T16448 | 229-233 | NNP | denotes | EMSA |
| T16447 | 228-229 | -LRB- | denotes | ( |
| T16446 | 222-227 | NN | denotes | assay |
| T16445 | 207-221 | NN | denotes | mobility-shift |
| T16444 | 191-206 | JJ | denotes | electrophoretic |
| T16443 | 188-190 | DT | denotes | an |
| T16442 | 178-187 | VBD | denotes | performed |
| T16441 | 175-177 | PRP | denotes | we |
| T16440 | 173-174 | , | denotes | , |
| T16439 | 163-173 | NN | denotes | expression |
| T16438 | 157-162 | NNP | denotes | IL-17 |
| T16437 | 148-156 | VBG | denotes | inducing |
| T16436 | 144-147 | IN | denotes | for |
| T16435 | 132-143 | JJ | denotes | responsible |
| T16434 | 128-131 | CC | denotes | and |
| T16433 | 126-127 | , | denotes | , |
| T16432 | 121-126 | NNP | denotes | IL-15 |
| T16431 | 117-120 | CC | denotes | and |
| T16430 | 113-116 | NNP | denotes | PHA |
| T16429 | 111-112 | , | denotes | , |
| T16428 | 110-111 | DT | denotes | A |
| T16427 | 97-109 | JJ | denotes | concanavalin |
| T16426 | 95-96 | , | denotes | , |
| T16425 | 86-95 | JJ | denotes | anti-CD28 |
| T16424 | 81-85 | CC | denotes | plus |
| T16423 | 72-80 | JJ | denotes | anti-CD3 |
| T16422 | 69-71 | IN | denotes | by |
| T16421 | 59-68 | VBN | denotes | activated |
| T16420 | 51-58 | NN | denotes | pathway |
| T16419 | 41-50 | VBG | denotes | signaling |
| T16418 | 27-40 | JJ | denotes | intracellular |
| T16417 | 23-26 | DT | denotes | the |
| T16416 | 15-22 | RB | denotes | further |
| T16415 | 3-14 | VB | denotes | investigate |
| T16414 | 0-2 | TO | denotes | To |
| T16642 | 1227-1231 | IN | denotes | that |
| T16641 | 1213-1226 | VBG | denotes | demonstrating |
| T16640 | 1211-1212 | , | denotes | , |
| T16639 | 1210-1211 | -RRB- | denotes | ) |
| T16638 | 1205-1210 | VBN | denotes | shown |
| T16637 | 1201-1204 | RB | denotes | not |
| T16636 | 1196-1200 | NNS | denotes | data |
| T16635 | 1195-1196 | -LRB- | denotes | ( |
| T16634 | 1185-1194 | JJ | denotes | anti-CD28 |
| T16633 | 1180-1184 | CC | denotes | plus |
| T16632 | 1171-1179 | JJ | denotes | anti-CD3 |
| T16631 | 1166-1170 | IN | denotes | with |
| T16630 | 1154-1165 | NN | denotes | stimulation |
| T16629 | 1151-1153 | IN | denotes | by |
| T16628 | 1141-1150 | VBN | denotes | activated |
| T16627 | 1137-1140 | RB | denotes | not |
| T16626 | 1133-1136 | VBD | denotes | was |
| T16625 | 1125-1132 | NN | denotes | pathway |
| T16624 | 1120-1124 | NNP | denotes | AP-1 |
| T16623 | 1116-1119 | DT | denotes | the |
| T16622 | 1114-1115 | , | denotes | , |
| T16621 | 1106-1114 | NN | denotes | contrast |
| R8904 | T16414 | T16415 | aux | To,investigate |
| R8905 | T16415 | T16442 | advcl | investigate,performed |
| R8906 | T16416 | T16415 | advmod | further,investigate |
| R8907 | T16417 | T16420 | det | the,pathway |
| R8908 | T16418 | T16420 | amod | intracellular,pathway |
| R8909 | T16419 | T16420 | amod | signaling,pathway |
| R8910 | T16420 | T16415 | dobj | pathway,investigate |
| R8911 | T16421 | T16420 | acl | activated,pathway |
| R8912 | T16422 | T16421 | agent | by,activated |
| R8913 | T16423 | T16430 | amod | anti-CD3,PHA |
| R8914 | T16424 | T16423 | cc | plus,anti-CD3 |
| R8915 | T16425 | T16423 | conj | anti-CD28,anti-CD3 |
| R8916 | T16426 | T16425 | punct | ",",anti-CD28 |
| R8917 | T16427 | T16428 | compound | concanavalin,A |
| R8918 | T16428 | T16425 | conj | A,anti-CD28 |
| R8919 | T16429 | T16428 | punct | ",",A |
| R8920 | T16430 | T16422 | pobj | PHA,by |
| R8921 | T16431 | T16430 | cc | and,PHA |
| R8922 | T16432 | T16430 | conj | IL-15,PHA |
| R8923 | T16433 | T16432 | punct | ",",IL-15 |
| R8924 | T16434 | T16421 | cc | and,activated |
| R8925 | T16435 | T16421 | conj | responsible,activated |
| R8926 | T16436 | T16435 | prep | for,responsible |
| R8927 | T16437 | T16436 | pcomp | inducing,for |
| R8928 | T16438 | T16439 | compound | IL-17,expression |
| R8929 | T16439 | T16437 | dobj | expression,inducing |
| R8930 | T16440 | T16442 | punct | ",",performed |
| R8931 | T16441 | T16442 | nsubj | we,performed |
| R8932 | T16442 | T16442 | ROOT | performed,performed |
| R8933 | T16443 | T16446 | det | an,assay |
| R8934 | T16444 | T16446 | amod | electrophoretic,assay |
| R8935 | T16445 | T16446 | compound | mobility-shift,assay |
| R8936 | T16446 | T16442 | dobj | assay,performed |
| R8937 | T16447 | T16446 | punct | (,assay |
| R8938 | T16448 | T16446 | appos | EMSA,assay |
| R8939 | T16449 | T16446 | punct | ),assay |
| R8940 | T16450 | T16446 | prep | of,assay |
| R8941 | T16451 | T16453 | compound | NF-κB,sites |
| R8942 | T16452 | T16453 | compound | recognition,sites |
| R8943 | T16453 | T16450 | pobj | sites,of |
| R8944 | T16454 | T16453 | prep | in,sites |
| R8945 | T16455 | T16456 | det | the,promoters |
| R8946 | T16456 | T16454 | pobj | promoters,in |
| R8947 | T16457 | T16456 | prep | of,promoters |
| R8948 | T16458 | T16457 | pobj | IL-17,of |
| R8949 | T16459 | T16442 | punct | .,performed |
| R8950 | T16460 | T16461 | mark | As,shown |
| R8951 | T16461 | T16471 | advcl | shown,stimulated |
| R8952 | T16462 | T16461 | prep | in,shown |
| R8953 | T16463 | T16462 | pobj | Fig.,in |
| R8954 | T16464 | T16463 | nummod | 7a,Fig. |
| R8955 | T16465 | T16463 | punct | ",",Fig. |
| R8956 | T16466 | T16467 | amod | nuclear,extracts |
| R8957 | T16467 | T16471 | nsubj | extracts,stimulated |
| R8958 | T16468 | T16467 | prep | from,extracts |
| R8959 | T16469 | T16470 | compound | RA,PBMC |
| R8960 | T16470 | T16468 | pobj | PBMC,from |
| R8961 | T16471 | T16471 | ROOT | stimulated,stimulated |
| R8962 | T16472 | T16471 | prep | with,stimulated |
| R8963 | T16473 | T16472 | pobj | anti-CD3,with |
| R8964 | T16474 | T16473 | cc | plus,anti-CD3 |
| R8965 | T16475 | T16473 | conj | anti-CD28,anti-CD3 |
| R8966 | T16476 | T16477 | punct | (,lane |
| R8967 | T16477 | T16473 | appos | lane,anti-CD3 |
| R8968 | T16478 | T16477 | nummod | 2,lane |
| R8969 | T16479 | T16471 | punct | ),stimulated |
| R8970 | T16480 | T16471 | conj | demonstrated,stimulated |
| R8971 | T16481 | T16482 | amod | increased,binding |
| R8972 | T16482 | T16480 | dobj | binding,demonstrated |
| R8973 | T16483 | T16482 | prep | of,binding |
| R8974 | T16484 | T16483 | pobj | NF-κB,of |
| R8975 | T16485 | T16484 | prep | to,NF-κB |
| R8976 | T16486 | T16487 | compound | IL-17,promoters |
| R8977 | T16487 | T16485 | pobj | promoters,to |
| R8978 | T16488 | T16480 | prep | in,demonstrated |
| R8979 | T16489 | T16488 | pobj | comparison,in |
| R8980 | T16490 | T16489 | prep | with,comparison |
| R8981 | T16491 | T16490 | pobj | that,with |
| R8982 | T16492 | T16491 | prep | of,that |
| R8983 | T16493 | T16492 | pobj | controls,of |
| R8984 | T16494 | T16495 | punct | (,lane |
| R8985 | T16495 | T16493 | parataxis | lane,controls |
| R8986 | T16496 | T16495 | nummod | 1,lane |
| R8987 | T16497 | T16495 | punct | ),lane |
| R8988 | T16498 | T16471 | punct | .,stimulated |
| R8989 | T16499 | T16501 | det | A,assay |
| R8990 | T16500 | T16501 | compound | supershift,assay |
| R8991 | T16501 | T16502 | nsubj | assay,demonstrated |
| R8992 | T16502 | T16502 | ROOT | demonstrated,demonstrated |
| R8993 | T16503 | T16504 | amod | shifted,bands |
| R8994 | T16504 | T16502 | dobj | bands,demonstrated |
| R8995 | T16505 | T16502 | prep | in,demonstrated |
| R8996 | T16506 | T16510 | nummod | p65,lanes |
| R8997 | T16507 | T16506 | cc | and,p65 |
| R8998 | T16508 | T16506 | conj | p50,p65 |
| R8999 | T16509 | T16510 | punct | (,lanes |
| R9000 | T16510 | T16505 | pobj | lanes,in |
| R9001 | T16511 | T16510 | nummod | 3,lanes |
| R9002 | T16512 | T16511 | cc | and,3 |
| R9003 | T16513 | T16511 | conj | 4,3 |
| R9004 | T16514 | T16511 | punct | ),3 |
| R9005 | T16515 | T16510 | neg | not,lanes |
| R9006 | T16516 | T16510 | prep | in,lanes |
| R9007 | T16517 | T16516 | pobj | c-Rel,in |
| R9008 | T16518 | T16519 | punct | (,lane |
| R9009 | T16519 | T16517 | appos | lane,c-Rel |
| R9010 | T16520 | T16519 | nummod | 5,lane |
| R9011 | T16521 | T16519 | punct | ),lane |
| R9012 | T16522 | T16502 | punct | .,demonstrated |
| R9013 | T16523 | T16530 | prep | In,observed |
| R9014 | T16524 | T16523 | pobj | normal,In |
| R9015 | T16525 | T16530 | nsubjpass | PBMC,observed |
| R9016 | T16526 | T16528 | det | the,pattern |
| R9017 | T16527 | T16528 | amod | same,pattern |
| R9018 | T16528 | T16525 | appos | pattern,PBMC |
| R9019 | T16529 | T16530 | auxpass | was,observed |
| R9020 | T16530 | T16530 | ROOT | observed,observed |
| R9021 | T16531 | T16530 | punct | ",",observed |
| R9022 | T16532 | T16530 | cc | but,observed |
| R9023 | T16533 | T16534 | det | the,degree |
| R9024 | T16534 | T16542 | nsubj | degree,was |
| R9025 | T16535 | T16534 | prep | of,degree |
| R9026 | T16536 | T16537 | amod | NF-κB,activation |
| R9027 | T16537 | T16535 | pobj | activation,of |
| R9028 | T16538 | T16537 | prep | by,activation |
| R9029 | T16539 | T16542 | nsubj | anti-CD3,was |
| R9030 | T16540 | T16539 | cc | plus,anti-CD3 |
| R9031 | T16541 | T16539 | conj | anti-CD28,anti-CD3 |
| R9032 | T16542 | T16530 | conj | was,observed |
| R9033 | T16543 | T16544 | advmod | less,intense |
| R9034 | T16544 | T16542 | acomp | intense,was |
| R9035 | T16545 | T16544 | prep | than,intense |
| R9036 | T16546 | T16545 | pobj | that,than |
| R9037 | T16547 | T16546 | prep | in,that |
| R9038 | T16548 | T16549 | compound | RA,PBMC |
| R9039 | T16549 | T16547 | pobj | PBMC,in |
| R9040 | T16550 | T16549 | punct | (,PBMC |
| R9041 | T16551 | T16549 | appos | Fig.,PBMC |
| R9042 | T16552 | T16551 | nummod | 7b,Fig. |
| R9043 | T16553 | T16549 | punct | ),PBMC |
| R9044 | T16554 | T16542 | punct | .,was |
| R9045 | T16555 | T16556 | aux | To,confirm |
| R9046 | T16556 | T16566 | advcl | confirm,performed |
| R9047 | T16557 | T16558 | det | the,link |
| R9048 | T16558 | T16556 | dobj | link,confirm |
| R9049 | T16559 | T16558 | prep | between,link |
| R9050 | T16560 | T16561 | amod | PI3K,activity |
| R9051 | T16561 | T16559 | pobj | activity,between |
| R9052 | T16562 | T16561 | cc | and,activity |
| R9053 | T16563 | T16561 | conj | NF-κB,activity |
| R9054 | T16564 | T16566 | punct | ",",performed |
| R9055 | T16565 | T16566 | nsubj | we,performed |
| R9056 | T16566 | T16566 | ROOT | performed,performed |
| R9057 | T16567 | T16566 | dobj | EMSA,performed |
| R9058 | T16568 | T16569 | aux | to,determine |
| R9059 | T16569 | T16566 | advcl | determine,performed |
| R9060 | T16570 | T16573 | det | the,activity |
| R9061 | T16571 | T16573 | amod | NF-κB,activity |
| R9062 | T16572 | T16573 | amod | binding,activity |
| R9063 | T16573 | T16569 | dobj | activity,determine |
| R9064 | T16574 | T16569 | prep | after,determine |
| R9065 | T16575 | T16574 | pobj | treatment,after |
| R9066 | T16576 | T16575 | prep | with,treatment |
| R9067 | T16577 | T16578 | det | both,LY294002 |
| R9068 | T16578 | T16576 | pobj | LY294002,with |
| R9069 | T16579 | T16578 | cc | and,LY294002 |
| R9070 | T16580 | T16578 | conj | PDTC,LY294002 |
| R9071 | T16581 | T16566 | punct | .,performed |
| R9072 | T16582 | T16583 | preconj | Both,agents |
| R9073 | T16583 | T16584 | nsubj | agents,block |
| R9074 | T16584 | T16584 | ROOT | block,block |
| R9075 | T16585 | T16587 | nmod | NF-κB,activity |
| R9076 | T16586 | T16587 | amod | DNA-binding,activity |
| R9077 | T16587 | T16584 | dobj | activity,block |
| R9078 | T16588 | T16587 | prep | in,activity |
| R9079 | T16589 | T16591 | det | the,promoter |
| R9080 | T16590 | T16591 | compound | IL-17,promoter |
| R9081 | T16591 | T16588 | pobj | promoter,in |
| R9082 | T16592 | T16584 | punct | (,block |
| R9083 | T16593 | T16584 | npadvmod | Fig.,block |
| R9084 | T16594 | T16593 | nummod | 7c,Fig. |
| R9085 | T16595 | T16584 | punct | ),block |
| R9086 | T16596 | T16584 | punct | .,block |
| R9087 | T16597 | T16598 | amod | Western,blotting |
| R9088 | T16598 | T16601 | nsubj | blotting,showed |
| R9089 | T16599 | T16598 | prep | for,blotting |
| R9090 | T16600 | T16601 | nsubj | IκB-α,showed |
| R9091 | T16601 | T16601 | ROOT | showed,showed |
| R9092 | T16602 | T16601 | dobj | inhibition,showed |
| R9093 | T16603 | T16602 | prep | of,inhibition |
| R9094 | T16604 | T16603 | pobj | degradation,of |
| R9095 | T16605 | T16604 | prep | of,degradation |
| R9096 | T16606 | T16605 | pobj | IκB-α,of |
| R9097 | T16607 | T16601 | prep | by,showed |
| R9098 | T16608 | T16607 | pobj | LY294002,by |
| R9099 | T16609 | T16608 | cc | and,LY294002 |
| R9100 | T16610 | T16608 | conj | PDTC,LY294002 |
| R9101 | T16611 | T16601 | prep | at,showed |
| R9102 | T16612 | T16614 | det | the,time |
| R9103 | T16613 | T16614 | amod | same,time |
| R9104 | T16614 | T16611 | pobj | time,at |
| R9105 | T16615 | T16601 | punct | (,showed |
| R9106 | T16616 | T16601 | dobj | Fig.,showed |
| R9107 | T16617 | T16616 | nummod | 7c,Fig. |
| R9108 | T16618 | T16616 | punct | ),Fig. |
| R9109 | T16619 | T16601 | punct | .,showed |
| R9110 | T16620 | T16628 | prep | In,activated |
| R9111 | T16621 | T16620 | pobj | contrast,In |
| R9112 | T16622 | T16628 | punct | ",",activated |
| R9113 | T16623 | T16625 | det | the,pathway |
| R9114 | T16624 | T16625 | compound | AP-1,pathway |
| R9115 | T16625 | T16628 | nsubjpass | pathway,activated |
| R9116 | T16626 | T16628 | auxpass | was,activated |
| R9117 | T16627 | T16628 | neg | not,activated |
| R9118 | T16628 | T16628 | ROOT | activated,activated |
| R9119 | T16629 | T16628 | agent | by,activated |
| R9120 | T16630 | T16629 | pobj | stimulation,by |
| R9121 | T16631 | T16628 | prep | with,activated |
| R9122 | T16632 | T16636 | amod | anti-CD3,data |
| R9123 | T16633 | T16632 | cc | plus,anti-CD3 |
| R9124 | T16634 | T16632 | conj | anti-CD28,anti-CD3 |
| R9125 | T16635 | T16636 | punct | (,data |
| R9126 | T16636 | T16631 | pobj | data,with |
| R9127 | T16637 | T16638 | neg | not,shown |
| R9128 | T16638 | T16636 | acl | shown,data |
| R9129 | T16639 | T16636 | punct | ),data |
| R9130 | T16640 | T16628 | punct | ",",activated |
| R9131 | T16641 | T16628 | advcl | demonstrating,activated |
| R9132 | T16642 | T16644 | mark | that,is |
| R9133 | T16643 | T16644 | nsubj | NF-κB,is |
| R9134 | T16644 | T16641 | ccomp | is,demonstrating |
| R9135 | T16645 | T16649 | det | the,pathway |
| R9136 | T16646 | T16649 | amod | main,pathway |
| R9137 | T16647 | T16649 | amod | intracellular,pathway |
| R9138 | T16648 | T16649 | amod | signaling,pathway |
| R9139 | T16649 | T16644 | attr | pathway,is |
| R9140 | T16650 | T16649 | prep | in,pathway |
| R9141 | T16651 | T16652 | amod | IL-17,production |
| R9142 | T16652 | T16650 | pobj | production,in |
| R9143 | T16653 | T16649 | prep | by,pathway |
| R9144 | T16654 | T16655 | amod | activated,PBMC |
| R9145 | T16655 | T16653 | pobj | PBMC,by |
| R9146 | T16656 | T16649 | prep | from,pathway |
| R9147 | T16657 | T16656 | pobj | patients,from |
| R9148 | T16658 | T16649 | prep | with,pathway |
| R9149 | T16659 | T16658 | pobj | RA,with |
| R9150 | T16660 | T16628 | punct | .,activated |
bionlp-st-ge-2016-test-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16257 | 1232-1237 | Protein | denotes | NF-κB |
| T16256 | 1185-1194 | Protein | denotes | anti-CD28 |
| T16255 | 1171-1179 | Protein | denotes | anti-CD3 |
| T16254 | 1120-1124 | Protein | denotes | AP-1 |
| T16253 | 1019-1029 | Negative_regulation | denotes | inhibition |
| T16252 | 1033-1044 | Protein_catabolism | denotes | degradation |
| T16251 | 1093-1100 | Protein | denotes | Fig. 7c |
| T16250 | 1048-1053 | Protein | denotes | IκB-α |
| T16249 | 1006-1011 | Protein | denotes | IκB-α |
| T16248 | 919-924 | Negative_regulation | denotes | block |
| T16247 | 919-924 | Negative_regulation | denotes | block |
| T16246 | 975-982 | Protein | denotes | Fig. 7c |
| T16245 | 959-973 | Protein | denotes | IL-17 promoter |
| T16241 | 797-802 | Protein | denotes | NF-κB |
| T16240 | 779-783 | Protein | denotes | PI3K |
| T16239 | 711-718 | Binding | denotes | intense |
| T16238 | 664-674 | Positive_regulation | denotes | activation |
| T16237 | 664-674 | Positive_regulation | denotes | activation |
| T16236 | 741-748 | Protein | denotes | Fig. 7b |
| T16235 | 732-739 | Protein | denotes | RA PBMC |
| T16234 | 692-701 | Protein | denotes | anti-CD28 |
| T16233 | 678-686 | Protein | denotes | anti-CD3 |
| T16232 | 658-663 | Protein | denotes | NF-κB |
| T16231 | 551-554 | Protein | denotes | p50 |
| T16230 | 543-546 | Protein | denotes | p65 |
| T16229 | 402-411 | Positive_regulation | denotes | increased |
| T16228 | 402-411 | Positive_regulation | denotes | increased |
| T16227 | 412-419 | Binding | denotes | binding |
| T16226 | 412-419 | Binding | denotes | binding |
| T16225 | 340-350 | Positive_regulation | denotes | stimulated |
| T16224 | 340-350 | Positive_regulation | denotes | stimulated |
| T16223 | 432-447 | Protein | denotes | IL-17 promoters |
| T16222 | 423-428 | Protein | denotes | NF-κB |
| T16221 | 370-379 | Protein | denotes | anti-CD28 |
| T16220 | 356-364 | Protein | denotes | anti-CD3 |
| T16219 | 332-339 | Protein | denotes | RA PBMC |
| T16218 | 301-304 | Protein | denotes | Fig |
| T16217 | 148-156 | Positive_regulation | denotes | inducing |
| T16216 | 163-173 | Gene_expression | denotes | expression |
| T16215 | 282-287 | Protein | denotes | IL-17 |
| T16214 | 238-261 | Protein | denotes | NF-κB recognition sites |
| T16213 | 157-162 | Protein | denotes | IL-17 |
| T16212 | 121-126 | Protein | denotes | IL-15 |
| T16211 | 113-116 | Protein | denotes | PHA |
| T16210 | 97-111 | Protein | denotes | concanavalin A |
| T16209 | 86-95 | Protein | denotes | anti-CD28 |
| T16208 | 72-80 | Protein | denotes | anti-CD3 |
| T16244 | 925-930 | Protein | denotes | NF-κB |
| T16243 | 845-852 | Binding | denotes | binding |
| T16242 | 839-844 | Protein | denotes | NF-κB |
| R8840 | T16213 | T16216 | themeOf | IL-17,expression |
| R8841 | T16216 | T16217 | themeOf | expression,inducing |
| R8842 | T16219 | T16224 | themeOf | RA PBMC,stimulated |
| R8843 | T16220 | T16225 | themeOf | anti-CD3,stimulated |
| R8844 | T16221 | T16224 | causeOf | anti-CD28,stimulated |
| R8845 | T16221 | T16225 | causeOf | anti-CD28,stimulated |
| R8846 | T16222 | T16226 | themeOf | NF-κB,binding |
| R8847 | T16222 | T16227 | themeOf | NF-κB,binding |
| R8848 | T16223 | T16227 | themeOf | IL-17 promoters,binding |
| R8849 | T16226 | T16228 | themeOf | binding,increased |
| R8850 | T16227 | T16229 | themeOf | binding,increased |
| R8851 | T16232 | T16237 | themeOf | NF-κB,activation |
| R8852 | T16232 | T16238 | themeOf | NF-κB,activation |
| R8853 | T16233 | T16237 | causeOf | anti-CD3,activation |
| R8854 | T16234 | T16238 | causeOf | anti-CD28,activation |
| R8855 | T16235 | T16239 | themeOf | RA PBMC,intense |
| R8856 | T16242 | T16243 | themeOf | NF-κB,binding |
| R8857 | T16245 | T16247 | themeOf | IL-17 promoter,block |
| R8858 | T16246 | T16248 | themeOf | Fig. 7c,block |
| R8859 | T16250 | T16252 | themeOf | IκB-α,degradation |
| R8860 | T16252 | T16253 | themeOf | degradation,inhibition |
testone
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T15531 | 1305-1314 | Positive_regulation | denotes | activated |
| T15530 | 1291-1301 | Gene_expression | denotes | production |
| T15529 | 1033-1044 | Protein_catabolism | denotes | degradation |
| T15528 | 1019-1029 | Negative_regulation | denotes | inhibition |
| T15527 | 935-942 | Binding | denotes | binding |
| T15526 | 919-924 | Negative_regulation | denotes | block |
| T15525 | 845-852 | Binding | denotes | binding |
| T15524 | 412-419 | Binding | denotes | binding |
| T15523 | 402-411 | Positive_regulation | denotes | increased |
| T15522 | 163-173 | Gene_expression | denotes | expression |
| T15521 | 148-156 | Positive_regulation | denotes | inducing |
| T15520 | 132-143 | Regulation | denotes | responsible |
| T15519 | 1285-1290 | Protein | denotes | IL-17 |
| T15518 | 1190-1194 | Protein | denotes | CD28 |
| T15517 | 1120-1124 | Protein | denotes | AP-1 |
| T15516 | 1048-1053 | Protein | denotes | IκB-α |
| T15515 | 1006-1011 | Protein | denotes | IκB-α |
| T15514 | 959-964 | Protein | denotes | IL-17 |
| T15513 | 697-701 | Protein | denotes | CD28 |
| T15512 | 578-583 | Protein | denotes | c-Rel |
| T15511 | 551-554 | Protein | denotes | p50 |
| T15510 | 543-546 | Protein | denotes | p65 |
| T15509 | 432-437 | Protein | denotes | IL-17 |
| T15508 | 375-379 | Protein | denotes | CD28 |
| T15507 | 282-287 | Protein | denotes | IL-17 |
| T15506 | 157-162 | Protein | denotes | IL-17 |
| T15505 | 121-126 | Protein | denotes | IL-15 |
| T15504 | 113-116 | Protein | denotes | PHA |
| T15503 | 91-95 | Protein | denotes | CD28 |
| R8543 | T15504 | T15521 | causeOf | PHA,inducing |
| R8544 | T15505 | T15521 | causeOf | IL-15,inducing |
| R8545 | T15506 | T15522 | themeOf | IL-17,expression |
| R8546 | T15509 | T15524 | themeOf | IL-17,binding |
| R8547 | T15516 | T15529 | themeOf | IκB-α,degradation |
| R8548 | T15519 | T15530 | themeOf | IL-17,production |
| R8549 | T15521 | T15520 | themeOf | inducing,responsible |
| R8550 | T15522 | T15521 | themeOf | expression,inducing |
| R8551 | T15524 | T15523 | themeOf | binding,increased |
| R8552 | T15527 | T15526 | themeOf | binding,block |
| R8553 | T15529 | T15528 | themeOf | degradation,inhibition |