PMC:1064873 / 26212-26395 JSONTXT

Annnotations TAB JSON ListView MergeView

    LappsTest

    {"project":"LappsTest","denotations":[{"id":"T22099","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T22098","span":{"begin":168,"end":172},"obj":"Protein"},{"id":"T22097","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T22096","span":{"begin":76,"end":83},"obj":"Protein"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    pmc-enju-pas

    {"project":"pmc-enju-pas","denotations":[{"id":"T24973","span":{"begin":178,"end":182},"obj":"NN"},{"id":"T24972","span":{"begin":174,"end":177},"obj":"CC"},{"id":"T24971","span":{"begin":168,"end":173},"obj":"NN"},{"id":"T24970","span":{"begin":163,"end":167},"obj":"CC"},{"id":"T24969","span":{"begin":160,"end":162},"obj":"IN"},{"id":"T24968","span":{"begin":149,"end":159},"obj":"NN"},{"id":"T24967","span":{"begin":131,"end":148},"obj":"JJ"},{"id":"T24966","span":{"begin":128,"end":130},"obj":"IN"},{"id":"T24965","span":{"begin":117,"end":127},"obj":"NN"},{"id":"T24964","span":{"begin":111,"end":116},"obj":"NN"},{"id":"T24963","span":{"begin":101,"end":110},"obj":"JJ"},{"id":"T24962","span":{"begin":99,"end":100},"obj":"DT"},{"id":"T24961","span":{"begin":92,"end":98},"obj":"VB"},{"id":"T24960","span":{"begin":86,"end":91},"obj":"NN"},{"id":"T24959","span":{"begin":84,"end":85},"obj":"NN"},{"id":"T24958","span":{"begin":79,"end":83},"obj":"JJ"},{"id":"T24957","span":{"begin":76,"end":78},"obj":"NN"},{"id":"T24956","span":{"begin":70,"end":75},"obj":"PRP-DOLLAR-"},{"id":"T24955","span":{"begin":62,"end":69},"obj":"IN"},{"id":"T24954","span":{"begin":60,"end":61},"obj":"-COMMA-"},{"id":"T24953","span":{"begin":52,"end":60},"obj":"NN"},{"id":"T24952","span":{"begin":49,"end":51},"obj":"NN"},{"id":"T24951","span":{"begin":42,"end":48},"obj":"JJ"},{"id":"T24950","span":{"begin":39,"end":41},"obj":"IN"},{"id":"T24949","span":{"begin":31,"end":38},"obj":"VB"},{"id":"T24948","span":{"begin":28,"end":30},"obj":"VB"},{"id":"T24947","span":{"begin":24,"end":27},"obj":"MD"},{"id":"T24946","span":{"begin":19,"end":23},"obj":"RB"},{"id":"T24945","span":{"begin":12,"end":18},"obj":"NN"},{"id":"T24944","span":{"begin":5,"end":11},"obj":"JJ"},{"id":"T24943","span":{"begin":0,"end":4},"obj":"DT"}],"relations":[{"id":"R12010","pred":"arg1Of","subj":"T24945","obj":"T24943"},{"id":"R12011","pred":"arg1Of","subj":"T24945","obj":"T24944"},{"id":"R12012","pred":"arg1Of","subj":"T24945","obj":"T24947"},{"id":"R12013","pred":"arg1Of","subj":"T24945","obj":"T24948"},{"id":"R12014","pred":"arg2Of","subj":"T24945","obj":"T24949"},{"id":"R12015","pred":"arg1Of","subj":"T24949","obj":"T24946"},{"id":"R12016","pred":"arg2Of","subj":"T24949","obj":"T24947"},{"id":"R12017","pred":"arg2Of","subj":"T24949","obj":"T24948"},{"id":"R12018","pred":"arg1Of","subj":"T24949","obj":"T24950"},{"id":"R12019","pred":"arg1Of","subj":"T24949","obj":"T24954"},{"id":"R12020","pred":"arg1Of","subj":"T24949","obj":"T24955"},{"id":"R12021","pred":"arg2Of","subj":"T24953","obj":"T24950"},{"id":"R12022","pred":"arg1Of","subj":"T24953","obj":"T24951"},{"id":"R12023","pred":"arg1Of","subj":"T24953","obj":"T24952"},{"id":"R12024","pred":"arg1Of","subj":"T24960","obj":"T24956"},{"id":"R12025","pred":"arg1Of","subj":"T24960","obj":"T24957"},{"id":"R12026","pred":"arg1Of","subj":"T24960","obj":"T24958"},{"id":"R12027","pred":"arg1Of","subj":"T24960","obj":"T24959"},{"id":"R12028","pred":"arg1Of","subj":"T24960","obj":"T24961"},{"id":"R12029","pred":"arg2Of","subj":"T24961","obj":"T24955"},{"id":"R12030","pred":"arg2Of","subj":"T24965","obj":"T24961"},{"id":"R12031","pred":"arg1Of","subj":"T24965","obj":"T24962"},{"id":"R12032","pred":"arg1Of","subj":"T24965","obj":"T24963"},{"id":"R12033","pred":"arg1Of","subj":"T24965","obj":"T24964"},{"id":"R12034","pred":"arg1Of","subj":"T24965","obj":"T24966"},{"id":"R12035","pred":"arg2Of","subj":"T24968","obj":"T24966"},{"id":"R12036","pred":"arg1Of","subj":"T24968","obj":"T24967"},{"id":"R12037","pred":"arg1Of","subj":"T24968","obj":"T24969"},{"id":"R12038","pred":"arg1Of","subj":"T24971","obj":"T24972"},{"id":"R12039","pred":"arg2Of","subj":"T24972","obj":"T24969"},{"id":"R12040","pred":"arg1Of","subj":"T24972","obj":"T24970"},{"id":"R12041","pred":"arg2Of","subj":"T24973","obj":"T24972"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T23391","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T23390","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T23389","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T23388","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T23387","span":{"begin":79,"end":82},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T26378","span":{"begin":168,"end":173},"obj":"http://www.uniprot.org/uniprot/P01579"},{"id":"T26344","span":{"begin":111,"end":116},"obj":"http://www.uniprot.org/uniprot/P22301"},{"id":"T26454","span":{"begin":178,"end":182},"obj":"http://www.uniprot.org/uniprot/P60568"},{"id":"T24268","span":{"begin":131,"end":135},"obj":"http://www.uniprot.org/uniprot/P10747"},{"id":"T24244","span":{"begin":79,"end":82},"obj":"http://www.uniprot.org/uniprot/P01730"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T23663","span":{"begin":86,"end":91},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    GO-MF

    {"project":"GO-MF","denotations":[{"id":"T23620","span":{"begin":178,"end":182},"obj":"http://purl.obolibrary.org/obo/GO_0005134"},{"id":"T23564","span":{"begin":111,"end":116},"obj":"http://purl.obolibrary.org/obo/GO_0005141"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    sentences

    {"project":"sentences","denotations":[{"id":"T22812","span":{"begin":0,"end":183},"obj":"Sentence"},{"id":"T155","span":{"begin":0,"end":183},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    simple1

    {"project":"simple1","denotations":[{"id":"T24333","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T24332","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T24331","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T24330","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T24329","span":{"begin":79,"end":82},"obj":"Protein"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    BioNLP16_DUT

    {"project":"BioNLP16_DUT","denotations":[{"id":"T30167","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T30166","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T30165","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T30164","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T30163","span":{"begin":79,"end":82},"obj":"Protein"},{"id":"T30350","span":{"begin":101,"end":110},"obj":"Negative_regulation"},{"id":"T30349","span":{"begin":117,"end":127},"obj":"Negative_regulation"},{"id":"T30348","span":{"begin":149,"end":159},"obj":"Gene_expression"},{"id":"T30347","span":{"begin":136,"end":148},"obj":"Positive_regulation"}],"relations":[{"id":"R16110","pred":"themeOf","subj":"T30164","obj":"T30350"},{"id":"R16111","pred":"themeOf","subj":"T30164","obj":"T30349"},{"id":"R16112","pred":"themeOf","subj":"T30165","obj":"T30347"},{"id":"R16113","pred":"themeOf","subj":"T30166","obj":"T30348"},{"id":"R16114","pred":"themeOf","subj":"T30167","obj":"T30348"},{"id":"R16171","pred":"themeOf","subj":"T30348","obj":"T30349"},{"id":"R16172","pred":"themeOf","subj":"T30348","obj":"T30349"},{"id":"R16173","pred":"themeOf","subj":"T30348","obj":"T30347"},{"id":"R16174","pred":"themeOf","subj":"T30348","obj":"T30347"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    BioNLP16_Messiy

    {"project":"BioNLP16_Messiy","denotations":[{"id":"T26710","span":{"begin":149,"end":159},"obj":"Gene_expression"},{"id":"T26709","span":{"begin":101,"end":110},"obj":"Negative_regulation"},{"id":"T26708","span":{"begin":136,"end":148},"obj":"Positive_regulation"},{"id":"T26707","span":{"begin":117,"end":127},"obj":"Negative_regulation"},{"id":"T26523","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T26522","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T26521","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T26520","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T26519","span":{"begin":79,"end":82},"obj":"Protein"}],"relations":[{"id":"R13486","pred":"themeOf","subj":"T26520","obj":"T26709"},{"id":"R13488","pred":"themeOf","subj":"T26521","obj":"T26708"},{"id":"R13489","pred":"themeOf","subj":"T26522","obj":"T26710"},{"id":"R13491","pred":"themeOf","subj":"T26523","obj":"T26710"},{"id":"R13576","pred":"themeOf","subj":"T26710","obj":"T26707"},{"id":"R13578","pred":"themeOf","subj":"T26710","obj":"T26707"},{"id":"R13579","pred":"themeOf","subj":"T26710","obj":"T26708"},{"id":"R13580","pred":"themeOf","subj":"T26710","obj":"T26708"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    DLUT931

    {"project":"DLUT931","denotations":[{"id":"T28806","span":{"begin":136,"end":148},"obj":"Positive_regulation"},{"id":"T28805","span":{"begin":117,"end":127},"obj":"Negative_regulation"},{"id":"T28804","span":{"begin":149,"end":159},"obj":"Gene_expression"},{"id":"T28803","span":{"begin":101,"end":110},"obj":"Negative_regulation"},{"id":"T28607","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T28606","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T28605","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T28604","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T28603","span":{"begin":79,"end":82},"obj":"Protein"}],"relations":[{"id":"R15395","pred":"themeOf","subj":"T28604","obj":"T28803"},{"id":"R15397","pred":"causeOf","subj":"T28605","obj":"T28806"},{"id":"R15399","pred":"themeOf","subj":"T28606","obj":"T28804"},{"id":"R15471","pred":"themeOf","subj":"T28804","obj":"T28805"},{"id":"R15472","pred":"themeOf","subj":"T28804","obj":"T28806"},{"id":"R15473","pred":"themeOf","subj":"T28804","obj":"T28805"},{"id":"R15474","pred":"themeOf","subj":"T28804","obj":"T28806"},{"id":"R15398","pred":"causeOf","subj":"T28605","obj":"T28806"},{"id":"R15400","pred":"themeOf","subj":"T28607","obj":"T28804"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    bionlp-st-ge-2016-test-ihmc

    {"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T30086","span":{"begin":128,"end":182},"obj":"Positive_regulation"},{"id":"T30085","span":{"begin":128,"end":182},"obj":"Positive_regulation"},{"id":"T30082","span":{"begin":0,"end":61},"obj":"Negative_regulation"},{"id":"T30028","span":{"begin":128,"end":182},"obj":"Gene_expression"},{"id":"T30027","span":{"begin":128,"end":182},"obj":"Gene_expression"},{"id":"T30022","span":{"begin":84,"end":182},"obj":"Negative_regulation"},{"id":"T30021","span":{"begin":84,"end":182},"obj":"Negative_regulation"},{"id":"T29992","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T29954","span":{"begin":76,"end":78},"obj":"Protein"},{"id":"T29951","span":{"begin":84,"end":91},"obj":"Entity"},{"id":"T29947","span":{"begin":131,"end":148},"obj":"Protein"},{"id":"T29920","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T29915","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T29755","span":{"begin":49,"end":51},"obj":"Protein"},{"id":"T29840","span":{"begin":76,"end":82},"obj":"Protein"}],"relations":[{"id":"R16011","pred":"causeOf","subj":"T29992","obj":"T30021"},{"id":"R16012","pred":"causeOf","subj":"T29992","obj":"T30022"},{"id":"R16026","pred":"themeOf","subj":"T29915","obj":"T30028"},{"id":"R16027","pred":"themeOf","subj":"T30027","obj":"T30021"},{"id":"R16028","pred":"themeOf","subj":"T30027","obj":"T30086"},{"id":"R16029","pred":"themeOf","subj":"T29920","obj":"T30027"},{"id":"R16030","pred":"themeOf","subj":"T30028","obj":"T30022"},{"id":"R16031","pred":"themeOf","subj":"T30028","obj":"T30085"},{"id":"R16042","pred":"causeOf","subj":"T29947","obj":"T30085"},{"id":"R16044","pred":"causeOf","subj":"T29947","obj":"T30086"}],"attributes":[{"id":"M68","pred":"Speculation","subj":"T30082","obj":"true"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    bionlp-st-ge-2016-spacy-parsed

    {"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T27313","span":{"begin":182,"end":183},"obj":"."},{"id":"T27312","span":{"begin":178,"end":182},"obj":"NNP"},{"id":"T27311","span":{"begin":174,"end":177},"obj":"CC"},{"id":"T27310","span":{"begin":168,"end":173},"obj":"NNP"},{"id":"T27309","span":{"begin":163,"end":167},"obj":"DT"},{"id":"T27308","span":{"begin":160,"end":162},"obj":"IN"},{"id":"T27307","span":{"begin":149,"end":159},"obj":"NN"},{"id":"T27306","span":{"begin":131,"end":148},"obj":"JJ"},{"id":"T27291","span":{"begin":52,"end":60},"obj":"NNS"},{"id":"T27290","span":{"begin":49,"end":51},"obj":"NNP"},{"id":"T27289","span":{"begin":42,"end":48},"obj":"JJ"},{"id":"T27288","span":{"begin":39,"end":41},"obj":"IN"},{"id":"T27287","span":{"begin":31,"end":38},"obj":"VBN"},{"id":"T27286","span":{"begin":28,"end":30},"obj":"VB"},{"id":"T27285","span":{"begin":24,"end":27},"obj":"MD"},{"id":"T27284","span":{"begin":19,"end":23},"obj":"RB"},{"id":"T27283","span":{"begin":12,"end":18},"obj":"NN"},{"id":"T27282","span":{"begin":5,"end":11},"obj":"JJ"},{"id":"T27281","span":{"begin":0,"end":4},"obj":"DT"},{"id":"T27305","span":{"begin":128,"end":130},"obj":"IN"},{"id":"T27304","span":{"begin":117,"end":127},"obj":"NN"},{"id":"T27303","span":{"begin":111,"end":116},"obj":"NN"},{"id":"T27302","span":{"begin":101,"end":110},"obj":"JJ"},{"id":"T27301","span":{"begin":99,"end":100},"obj":"DT"},{"id":"T27300","span":{"begin":92,"end":98},"obj":"VBD"},{"id":"T27299","span":{"begin":86,"end":91},"obj":"NNS"},{"id":"T27298","span":{"begin":84,"end":85},"obj":"NNP"},{"id":"T27297","span":{"begin":82,"end":83},"obj":"VBD"},{"id":"T27296","span":{"begin":79,"end":82},"obj":"NNP"},{"id":"T27295","span":{"begin":76,"end":78},"obj":"NNP"},{"id":"T27294","span":{"begin":70,"end":75},"obj":"PRP$"},{"id":"T27293","span":{"begin":62,"end":69},"obj":"IN"},{"id":"T27292","span":{"begin":60,"end":61},"obj":","}],"relations":[{"id":"R14021","pred":"det","subj":"T27281","obj":"T27283"},{"id":"R14022","pred":"amod","subj":"T27282","obj":"T27283"},{"id":"R14024","pred":"nsubjpass","subj":"T27283","obj":"T27287"},{"id":"R14025","pred":"advmod","subj":"T27284","obj":"T27287"},{"id":"R14027","pred":"aux","subj":"T27285","obj":"T27287"},{"id":"R14028","pred":"auxpass","subj":"T27286","obj":"T27287"},{"id":"R14029","pred":"ROOT","subj":"T27287","obj":"T27287"},{"id":"R14030","pred":"prep","subj":"T27288","obj":"T27287"},{"id":"R14032","pred":"amod","subj":"T27289","obj":"T27291"},{"id":"R14033","pred":"compound","subj":"T27290","obj":"T27291"},{"id":"R14035","pred":"pobj","subj":"T27291","obj":"T27288"},{"id":"R14039","pred":"punct","subj":"T27292","obj":"T27287"},{"id":"R14041","pred":"mark","subj":"T27293","obj":"T27300"},{"id":"R14042","pred":"poss","subj":"T27294","obj":"T27296"},{"id":"R14043","pred":"compound","subj":"T27295","obj":"T27296"},{"id":"R14045","pred":"nmod","subj":"T27296","obj":"T27299"},{"id":"R14046","pred":"amod","subj":"T27297","obj":"T27299"},{"id":"R14048","pred":"compound","subj":"T27298","obj":"T27299"},{"id":"R14049","pred":"nsubj","subj":"T27299","obj":"T27300"},{"id":"R14050","pred":"advcl","subj":"T27300","obj":"T27287"},{"id":"R14054","pred":"det","subj":"T27301","obj":"T27304"},{"id":"R14055","pred":"amod","subj":"T27302","obj":"T27304"},{"id":"R14057","pred":"compound","subj":"T27303","obj":"T27304"},{"id":"R14058","pred":"dobj","subj":"T27304","obj":"T27300"},{"id":"R14059","pred":"prep","subj":"T27305","obj":"T27304"},{"id":"R14061","pred":"amod","subj":"T27306","obj":"T27307"},{"id":"R14062","pred":"pobj","subj":"T27307","obj":"T27305"},{"id":"R14064","pred":"prep","subj":"T27308","obj":"T27307"},{"id":"R14065","pred":"preconj","subj":"T27309","obj":"T27310"},{"id":"R14066","pred":"pobj","subj":"T27310","obj":"T27308"},{"id":"R14068","pred":"cc","subj":"T27311","obj":"T27310"},{"id":"R14069","pred":"conj","subj":"T27312","obj":"T27310"},{"id":"R14070","pred":"punct","subj":"T27313","obj":"T27287"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    bionlp-st-ge-2016-test-tees

    {"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T23997","span":{"begin":136,"end":148},"obj":"Positive_regulation"},{"id":"T23996","span":{"begin":136,"end":148},"obj":"Positive_regulation"},{"id":"T23995","span":{"begin":117,"end":127},"obj":"Negative_regulation"},{"id":"T23994","span":{"begin":117,"end":127},"obj":"Negative_regulation"},{"id":"T23993","span":{"begin":149,"end":159},"obj":"Gene_expression"},{"id":"T23992","span":{"begin":149,"end":159},"obj":"Gene_expression"},{"id":"T23991","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T23990","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T23989","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T23988","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T23987","span":{"begin":79,"end":83},"obj":"Protein"}],"relations":[{"id":"R11441","pred":"causeOf","subj":"T23989","obj":"T23996"},{"id":"R11442","pred":"causeOf","subj":"T23989","obj":"T23997"},{"id":"R11443","pred":"themeOf","subj":"T23990","obj":"T23992"},{"id":"R11444","pred":"themeOf","subj":"T23991","obj":"T23993"},{"id":"R11445","pred":"themeOf","subj":"T23992","obj":"T23994"},{"id":"R11446","pred":"themeOf","subj":"T23992","obj":"T23996"},{"id":"R11447","pred":"themeOf","subj":"T23993","obj":"T23995"},{"id":"R11448","pred":"themeOf","subj":"T23993","obj":"T23997"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    test3

    {"project":"test3","denotations":[{"id":"T22546","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T22545","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T22544","span":{"begin":149,"end":159},"obj":"Gene_expression"},{"id":"T22543","span":{"begin":136,"end":148},"obj":"Positive_regulation"},{"id":"T22542","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T22541","span":{"begin":117,"end":127},"obj":"Negative_regulation"},{"id":"T22540","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T22539","span":{"begin":101,"end":110},"obj":"Negative_regulation"},{"id":"T22538","span":{"begin":79,"end":82},"obj":"Protein"},{"id":"T22303","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T22302","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T22301","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T22300","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T22299","span":{"begin":79,"end":82},"obj":"Protein"}],"relations":[{"id":"R11029","pred":"causeOf","subj":"T22540","obj":"T22541"},{"id":"R11030","pred":"themeOf","subj":"T22541","obj":"T22539"},{"id":"R11031","pred":"causeOf","subj":"T22542","obj":"T22543"},{"id":"R11032","pred":"themeOf","subj":"T22543","obj":"T22541"},{"id":"R11033","pred":"themeOf","subj":"T22544","obj":"T22543"},{"id":"R11034","pred":"themeOf","subj":"T22545","obj":"T22544"},{"id":"R11035","pred":"themeOf","subj":"T22546","obj":"T22544"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}

    testone

    {"project":"testone","denotations":[{"id":"T21771","span":{"begin":178,"end":182},"obj":"Protein"},{"id":"T21770","span":{"begin":168,"end":173},"obj":"Protein"},{"id":"T21769","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T21768","span":{"begin":111,"end":116},"obj":"Protein"},{"id":"T21767","span":{"begin":79,"end":82},"obj":"Protein"},{"id":"T21956","span":{"begin":149,"end":159},"obj":"Gene_expression"},{"id":"T21955","span":{"begin":136,"end":148},"obj":"Positive_regulation"},{"id":"T21954","span":{"begin":117,"end":127},"obj":"Negative_regulation"},{"id":"T21953","span":{"begin":101,"end":110},"obj":"Negative_regulation"}],"relations":[{"id":"R10864","pred":"causeOf","subj":"T21768","obj":"T21954"},{"id":"R10865","pred":"themeOf","subj":"T21768","obj":"T21953"},{"id":"R10866","pred":"causeOf","subj":"T21769","obj":"T21955"},{"id":"R10867","pred":"themeOf","subj":"T21770","obj":"T21956"},{"id":"R10868","pred":"themeOf","subj":"T21771","obj":"T21956"},{"id":"R10959","pred":"themeOf","subj":"T21955","obj":"T21954"},{"id":"R10960","pred":"themeOf","subj":"T21956","obj":"T21955"}],"text":"This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2."}