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PMC:1064873 / 25679-26395 JSONTXT

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LappsTest

Id Subject Object Predicate Lexical cue
T22099 711-715 Protein denotes IL-2
T22098 701-705 Protein denotes IFN-
T22097 664-668 Protein denotes CD28
T22096 609-616 Protein denotes PB CD4+
T22095 497-501 Protein denotes CD28
T22094 407-412 Protein denotes IL-10
T22093 358-379 Protein denotes MHC class II antigens
T22092 338-352 Protein denotes CD86 molecules
T22091 329-333 Protein denotes CD80
T22090 29-60 Protein denotes CD4+ T-cell cytokine production

2_test

Id Subject Object Predicate Lexical cue
15535835-11244051-4156908 152-153 11244051 denotes 1
15535835-8717520-4156909 381-383 8717520 denotes 10
15535835-8624620-4156910 384-386 8624620 denotes 18
15535835-8546719-4156910 384-386 8546719 denotes 18
15535835-10529123-4156910 384-386 10529123 denotes 18
15535835-11412299-4156911 528-530 11412299 denotes 33

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T24917 368-370 CD denotes II
T24916 362-367 NN denotes class
T24915 358-361 NN denotes MHC
T24914 354-357 CC denotes and
T24913 352-353 -COMMA- denotes ,
T24912 343-352 NN denotes molecules
T24911 338-342 NN denotes CD86
T24910 334-337 CC denotes and
T24909 329-333 NN denotes CD80
T24908 327-328 -COMMA- denotes ,
T24907 318-327 NN denotes cytokines
T24906 315-317 IN denotes of
T24905 308-314 NN denotes levels
T24904 303-307 JJ denotes high
T24903 295-302 VB denotes express
T24902 292-294 NN denotes ST
T24901 288-291 DT denotes the
T24900 285-287 IN denotes in
T24899 273-284 NN denotes macrophages
T24898 265-272 IN denotes because
T24897 263-264 -COMMA- denotes ,
T24896 261-263 NN denotes RA
T24895 258-260 IN denotes in
T24894 247-257 NN denotes activation
T24893 240-246 NN denotes T-cell
T24892 237-239 IN denotes of
T24891 232-236 NN denotes site
T24890 228-231 DT denotes the
T24889 225-227 IN denotes at
T24888 214-224 VB denotes restricted
T24887 211-213 VB denotes be
T24886 208-210 TO denotes to
T24885 200-207 VB denotes thought
T24884 197-199 VB denotes is
T24883 190-196 NN denotes effect
T24882 179-189 JJ denotes inhibitory
T24881 170-178 JJ denotes indirect
T24880 165-169 DT denotes this
T24879 163-164 -COMMA- denotes ,
T24878 156-163 RB denotes However
T24877 153-154 -RRB- denotes ]
T24876 152-153 CD denotes 1
T24875 151-152 -LRB- denotes [
T24874 142-150 NN denotes function
T24873 137-141 NN denotes cell
T24872 118-136 JJ denotes antigen-presenting
T24871 107-117 NN denotes macrophage
T24870 104-106 IN denotes of
T24869 93-103 NN denotes inhibition
T24868 89-92 PRP-DOLLAR- denotes its
T24867 86-88 IN denotes on
T24866 76-85 JJ denotes dependent
T24865 64-75 RB denotes principally
T24864 61-63 VB denotes is
T24863 50-60 NN denotes production
T24862 41-49 NN denotes cytokine
T24861 34-40 NN denotes T-cell
T24860 29-33 JJ denotes CD4+
T24859 26-28 IN denotes of
T24858 15-25 NN denotes inhibition
T24857 0-14 JJ denotes IL-10-mediated
T24973 711-715 NN denotes IL-2
T24972 707-710 CC denotes and
T24971 701-706 NN denotes IFN-γ
T24970 696-700 CC denotes both
T24969 693-695 IN denotes of
T24968 682-692 NN denotes production
T24967 664-681 JJ denotes CD28-costimulated
T24966 661-663 IN denotes of
T24965 650-660 NN denotes inhibition
T24964 644-649 NN denotes IL-10
T24963 634-643 JJ denotes defective
T24962 632-633 DT denotes a
T24961 625-631 VB denotes showed
T24960 619-624 NN denotes cells
T24959 617-618 NN denotes T
T24958 612-616 JJ denotes CD4+
T24957 609-611 NN denotes PB
T24956 603-608 PRP-DOLLAR- denotes their
T24955 595-602 IN denotes because
T24954 593-594 -COMMA- denotes ,
T24953 585-593 NN denotes patients
T24952 582-584 NN denotes RA
T24951 575-581 JJ denotes active
T24950 572-574 IN denotes in
T24949 564-571 VB denotes limited
T24948 561-563 VB denotes be
T24947 557-560 MD denotes may
T24946 552-556 RB denotes also
T24945 545-551 NN denotes effect
T24944 538-544 JJ denotes direct
T24943 533-537 DT denotes This
T24942 530-531 -RRB- denotes ]
T24941 528-530 CD denotes 33
T24940 527-528 -LRB- denotes [
T24939 511-526 NN denotes phosphorylation
T24938 502-510 NN denotes tyrosine
T24937 497-501 NN denotes CD28
T24936 486-496 VB denotes inhibiting
T24935 483-485 IN denotes by
T24934 466-482 NN denotes unresponsiveness
T24933 459-465 NN denotes T-cell
T24932 442-458 JJ denotes antigen-specific
T24931 438-441 DT denotes the
T24930 431-437 VB denotes induce
T24929 428-430 TO denotes to
T24928 422-427 VB denotes shown
T24927 417-421 VB denotes been
T24926 413-416 VB denotes has
T24925 407-412 NN denotes IL-10
T24924 405-406 -COMMA- denotes ,
T24923 397-405 RB denotes recently
T24922 392-396 RB denotes More
T24921 389-390 -RRB- denotes ]
T24920 381-389 CD denotes 10,18-20
T24919 380-381 -LRB- denotes [
T24918 371-379 NN denotes antigens
R11919 T24858 T24857 arg1Of inhibition,IL-10-mediated
R11920 T24858 T24859 arg1Of inhibition,of
R11921 T24858 T24864 arg1Of inhibition,is
R11922 T24858 T24866 arg1Of inhibition,dependent
R11923 T24863 T24859 arg2Of production,of
R11924 T24863 T24860 arg1Of production,CD4+
R11925 T24863 T24861 arg1Of production,T-cell
R11926 T24863 T24862 arg1Of production,cytokine
R11927 T24866 T24864 arg2Of dependent,is
R11928 T24866 T24865 arg1Of dependent,principally
R11929 T24866 T24867 arg1Of dependent,on
R11930 T24869 T24867 arg2Of inhibition,on
R11931 T24869 T24868 arg1Of inhibition,its
R11932 T24869 T24870 arg1Of inhibition,of
R11933 T24874 T24870 arg2Of function,of
R11934 T24874 T24871 arg1Of function,macrophage
R11935 T24874 T24872 arg1Of function,antigen-presenting
R11936 T24874 T24873 arg1Of function,cell
R11937 T24874 T24875 arg1Of function,[
R11938 T24876 T24875 arg2Of 1,[
R11939 T24877 T24875 arg3Of ],[
R11940 T24883 T24880 arg1Of effect,this
R11941 T24883 T24881 arg1Of effect,indirect
R11942 T24883 T24882 arg1Of effect,inhibitory
R11943 T24883 T24884 arg1Of effect,is
R11944 T24883 T24885 arg2Of effect,thought
R11945 T24883 T24887 arg1Of effect,be
R11946 T24883 T24888 arg2Of effect,restricted
R11947 T24885 T24878 arg1Of thought,However
R11948 T24885 T24879 arg1Of thought,","
R11949 T24885 T24884 arg2Of thought,is
R11950 T24885 T24897 arg1Of thought,","
R11951 T24885 T24898 arg1Of thought,because
R11952 T24888 T24885 arg3Of restricted,thought
R11953 T24888 T24886 arg1Of restricted,to
R11954 T24888 T24887 arg2Of restricted,be
R11955 T24888 T24889 arg1Of restricted,at
R11956 T24891 T24889 arg2Of site,at
R11957 T24891 T24890 arg1Of site,the
R11958 T24891 T24892 arg1Of site,of
R11959 T24894 T24892 arg2Of activation,of
R11960 T24894 T24893 arg1Of activation,T-cell
R11961 T24894 T24895 arg1Of activation,in
R11962 T24896 T24895 arg2Of RA,in
R11963 T24899 T24900 arg1Of macrophages,in
R11964 T24899 T24903 arg1Of macrophages,express
R11965 T24902 T24900 arg2Of ST,in
R11966 T24902 T24901 arg1Of ST,the
R11967 T24903 T24898 arg2Of express,because
R11968 T24905 T24903 arg2Of levels,express
R11969 T24905 T24904 arg1Of levels,high
R11970 T24905 T24906 arg1Of levels,of
R11971 T24907 T24908 arg1Of cytokines,","
R11972 T24908 T24910 arg1Of ",",and
R11973 T24909 T24908 arg2Of CD80,","
R11974 T24910 T24914 arg1Of and,and
R11975 T24912 T24910 arg2Of molecules,and
R11976 T24912 T24911 arg1Of molecules,CD86
R11977 T24914 T24906 arg2Of and,of
R11978 T24914 T24913 arg1Of and,","
R11979 T24918 T24914 arg2Of antigens,and
R11980 T24918 T24915 arg1Of antigens,MHC
R11981 T24918 T24916 arg1Of antigens,class
R11982 T24918 T24917 arg1Of antigens,II
R11983 T24918 T24919 arg1Of antigens,[
R11984 T24920 T24919 arg2Of "10,18-20",[
R11985 T24921 T24919 arg3Of ],[
R11986 T24923 T24922 arg1Of recently,More
R11987 T24925 T24926 arg1Of IL-10,has
R11988 T24925 T24927 arg1Of IL-10,been
R11989 T24925 T24928 arg2Of IL-10,shown
R11990 T24925 T24930 arg1Of IL-10,induce
R11991 T24925 T24936 arg1Of IL-10,inhibiting
R11992 T24928 T24923 arg1Of shown,recently
R11993 T24928 T24924 arg1Of shown,","
R11994 T24928 T24926 arg2Of shown,has
R11995 T24928 T24927 arg2Of shown,been
R11996 T24930 T24928 arg3Of induce,shown
R11997 T24930 T24929 arg1Of induce,to
R11998 T24930 T24935 arg1Of induce,by
R11999 T24934 T24930 arg2Of unresponsiveness,induce
R12000 T24934 T24931 arg1Of unresponsiveness,the
R12001 T24934 T24932 arg1Of unresponsiveness,antigen-specific
R12002 T24934 T24933 arg1Of unresponsiveness,T-cell
R12003 T24936 T24935 arg2Of inhibiting,by
R12004 T24936 T24940 arg1Of inhibiting,[
R12005 T24939 T24936 arg2Of phosphorylation,inhibiting
R12006 T24939 T24937 arg1Of phosphorylation,CD28
R12007 T24939 T24938 arg1Of phosphorylation,tyrosine
R12008 T24941 T24940 arg2Of 33,[
R12009 T24942 T24940 arg3Of ],[
R12010 T24945 T24943 arg1Of effect,This
R12011 T24945 T24944 arg1Of effect,direct
R12012 T24945 T24947 arg1Of effect,may
R12013 T24945 T24948 arg1Of effect,be
R12014 T24945 T24949 arg2Of effect,limited
R12015 T24949 T24946 arg1Of limited,also
R12016 T24949 T24947 arg2Of limited,may
R12017 T24949 T24948 arg2Of limited,be
R12018 T24949 T24950 arg1Of limited,in
R12019 T24949 T24954 arg1Of limited,","
R12020 T24949 T24955 arg1Of limited,because
R12021 T24953 T24950 arg2Of patients,in
R12022 T24953 T24951 arg1Of patients,active
R12023 T24953 T24952 arg1Of patients,RA
R12024 T24960 T24956 arg1Of cells,their
R12025 T24960 T24957 arg1Of cells,PB
R12026 T24960 T24958 arg1Of cells,CD4+
R12027 T24960 T24959 arg1Of cells,T
R12028 T24960 T24961 arg1Of cells,showed
R12029 T24961 T24955 arg2Of showed,because
R12030 T24965 T24961 arg2Of inhibition,showed
R12031 T24965 T24962 arg1Of inhibition,a
R12032 T24965 T24963 arg1Of inhibition,defective
R12033 T24965 T24964 arg1Of inhibition,IL-10
R12034 T24965 T24966 arg1Of inhibition,of
R12035 T24968 T24966 arg2Of production,of
R12036 T24968 T24967 arg1Of production,CD28-costimulated
R12037 T24968 T24969 arg1Of production,of
R12038 T24971 T24972 arg1Of IFN-γ,and
R12039 T24972 T24969 arg2Of and,of
R12040 T24972 T24970 arg1Of and,both
R12041 T24973 T24972 arg2Of IL-2,and

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T23391 711-715 Protein denotes IL-2
T23390 701-706 Protein denotes IFN-γ
T23389 664-668 Protein denotes CD28
T23388 644-649 Protein denotes IL-10
T23387 612-615 Protein denotes CD4
T23386 497-501 Protein denotes CD28
T23385 407-412 Protein denotes IL-10
T23384 338-342 Protein denotes CD86
T23383 329-333 Protein denotes CD80
T23382 29-32 Protein denotes CD4
T23381 0-5 Protein denotes IL-10

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T26378 701-706 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T26344 644-649 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T26343 407-412 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T26342 0-5 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T26454 711-715 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T24272 338-342 http://www.uniprot.org/uniprot/P42081 denotes CD86
T24270 329-333 http://www.uniprot.org/uniprot/P33681 denotes CD80
T24268 664-668 http://www.uniprot.org/uniprot/P10747 denotes CD28
T24267 497-501 http://www.uniprot.org/uniprot/P10747 denotes CD28
T24244 612-615 http://www.uniprot.org/uniprot/P01730 denotes CD4
T24243 29-32 http://www.uniprot.org/uniprot/P01730 denotes CD4

GO-BP

Id Subject Object Predicate Lexical cue
T22898 242-257 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T22897 240-257 http://purl.obolibrary.org/obo/GO_1903905 denotes T-cell activation
T22896 240-257 http://purl.obolibrary.org/obo/GO_0050863 denotes T-cell activation
T22895 240-257 http://purl.obolibrary.org/obo/GO_0050798 denotes T-cell activation
T22894 240-257 http://purl.obolibrary.org/obo/GO_0042110 denotes T-cell activation
T22893 240-257 http://purl.obolibrary.org/obo/GO_0051132 denotes T-cell activation
T22891 41-60 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T22890 36-60 http://purl.obolibrary.org/obo/GO_0035745 denotes cell cytokine production
T22889 36-60 http://purl.obolibrary.org/obo/GO_0035744 denotes cell cytokine production
T22888 36-60 http://purl.obolibrary.org/obo/GO_0002368 denotes cell cytokine production
T22887 36-60 http://purl.obolibrary.org/obo/GO_0032762 denotes cell cytokine production
T22886 36-60 http://purl.obolibrary.org/obo/GO_0002371 denotes cell cytokine production
T22885 36-60 http://purl.obolibrary.org/obo/GO_0002370 denotes cell cytokine production
T22884 34-60 http://purl.obolibrary.org/obo/GO_0002724 denotes T-cell cytokine production
T22883 34-60 http://purl.obolibrary.org/obo/GO_0002369 denotes T-cell cytokine production
T22880 511-526 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation

GO-CC

Id Subject Object Predicate Lexical cue
T23663 619-624 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

GO-MF

Id Subject Object Predicate Lexical cue
T23620 711-715 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T23564 644-649 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T23563 407-412 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T23562 0-5 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10

sentences

Id Subject Object Predicate Lexical cue
T22812 533-716 Sentence denotes This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2.
T22811 392-532 Sentence denotes More recently, IL-10 has been shown to induce the antigen-specific T-cell unresponsiveness by inhibiting CD28 tyrosine phosphorylation [33].
T22810 156-391 Sentence denotes However, this indirect inhibitory effect is thought to be restricted at the site of T-cell activation in RA, because macrophages in the ST express high levels of cytokines, CD80 and CD86 molecules, and MHC class II antigens [10,18-20].
T22809 0-155 Sentence denotes IL-10-mediated inhibition of CD4+ T-cell cytokine production is principally dependent on its inhibition of macrophage antigen-presenting cell function [1].
T152 0-155 Sentence denotes IL-10-mediated inhibition of CD4+ T-cell cytokine production is principally dependent on its inhibition of macrophage antigen-presenting cell function [1].
T153 156-391 Sentence denotes However, this indirect inhibitory effect is thought to be restricted at the site of T-cell activation in RA, because macrophages in the ST express high levels of cytokines, CD80 and CD86 molecules, and MHC class II antigens [10,18-20].
T154 392-532 Sentence denotes More recently, IL-10 has been shown to induce the antigen-specific T-cell unresponsiveness by inhibiting CD28 tyrosine phosphorylation [33].
T155 533-716 Sentence denotes This direct effect also may be limited in active RA patients, because their PB CD4+ T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2.

simple1

Id Subject Object Predicate Lexical cue
T24327 407-412 Protein denotes IL-10
T24326 338-342 Protein denotes CD86
T24325 329-333 Protein denotes CD80
T24324 29-32 Protein denotes CD4
T24323 0-5 Protein denotes IL-10
T24333 711-715 Protein denotes IL-2
T24332 701-706 Protein denotes IFN-γ
T24331 664-668 Protein denotes CD28
T24330 644-649 Protein denotes IL-10
T24329 612-615 Protein denotes CD4
T24328 497-501 Protein denotes CD28

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T30167 711-715 Protein denotes IL-2
T30166 701-706 Protein denotes IFN-γ
T30165 664-668 Protein denotes CD28
T30164 644-649 Protein denotes IL-10
T30163 612-615 Protein denotes CD4
T30162 497-501 Protein denotes CD28
T30161 407-412 Protein denotes IL-10
T30160 338-342 Protein denotes CD86
T30159 329-333 Protein denotes CD80
T30158 29-32 Protein denotes CD4
T30157 0-5 Protein denotes IL-10
T30350 634-643 Negative_regulation denotes defective
T30349 650-660 Negative_regulation denotes inhibition
T30348 682-692 Gene_expression denotes production
T30347 669-681 Positive_regulation denotes costimulated
T30346 511-526 Phosphorylation denotes phosphorylation
T30345 486-496 Negative_regulation denotes inhibiting
T30344 295-302 Gene_expression denotes express
R16106 T30159 T30344 themeOf CD80,express
R16108 T30162 T30346 themeOf CD28,phosphorylation
R16110 T30164 T30350 themeOf IL-10,defective
R16111 T30164 T30349 themeOf IL-10,inhibition
R16112 T30165 T30347 themeOf CD28,costimulated
R16113 T30166 T30348 themeOf IFN-γ,production
R16114 T30167 T30348 themeOf IL-2,production
R16169 T30346 T30345 themeOf phosphorylation,inhibiting
R16171 T30348 T30349 themeOf production,inhibition
R16172 T30348 T30349 themeOf production,inhibition
R16173 T30348 T30347 themeOf production,costimulated
R16174 T30348 T30347 themeOf production,costimulated

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T26710 682-692 Gene_expression denotes production
T26709 634-643 Negative_regulation denotes defective
T26708 669-681 Positive_regulation denotes costimulated
T26707 650-660 Negative_regulation denotes inhibition
T26706 511-526 Phosphorylation denotes phosphorylation
T26705 486-496 Negative_regulation denotes inhibiting
T26523 711-715 Protein denotes IL-2
T26522 701-706 Protein denotes IFN-γ
T26521 664-668 Protein denotes CD28
T26520 644-649 Protein denotes IL-10
T26519 612-615 Protein denotes CD4
T26518 497-501 Protein denotes CD28
T26517 407-412 Protein denotes IL-10
T26516 338-342 Protein denotes CD86
T26515 329-333 Protein denotes CD80
T26514 29-32 Protein denotes CD4
T26513 0-5 Protein denotes IL-10
R13482 T26517 T26705 causeOf IL-10,inhibiting
R13484 T26518 T26706 themeOf CD28,phosphorylation
R13486 T26520 T26709 themeOf IL-10,defective
R13488 T26521 T26708 themeOf CD28,costimulated
R13489 T26522 T26710 themeOf IFN-γ,production
R13491 T26523 T26710 themeOf IL-2,production
R13573 T26706 T26705 themeOf phosphorylation,inhibiting
R13576 T26710 T26707 themeOf production,inhibition
R13578 T26710 T26707 themeOf production,inhibition
R13579 T26710 T26708 themeOf production,costimulated
R13580 T26710 T26708 themeOf production,costimulated

DLUT931

Id Subject Object Predicate Lexical cue
T28806 669-681 Positive_regulation denotes costimulated
T28805 650-660 Negative_regulation denotes inhibition
T28804 682-692 Gene_expression denotes production
T28803 634-643 Negative_regulation denotes defective
T28802 486-496 Negative_regulation denotes inhibiting
T28801 511-526 Phosphorylation denotes phosphorylation
T28800 295-302 Gene_expression denotes express
T28799 6-14 Positive_regulation denotes mediated
T28798 15-25 Negative_regulation denotes inhibition
T28797 50-60 Gene_expression denotes production
T28607 711-715 Protein denotes IL-2
T28606 701-706 Protein denotes IFN-γ
T28605 664-668 Protein denotes CD28
T28604 644-649 Protein denotes IL-10
T28603 612-615 Protein denotes CD4
T28602 497-501 Protein denotes CD28
T28601 407-412 Protein denotes IL-10
T28600 338-342 Protein denotes CD86
T28599 329-333 Protein denotes CD80
T28598 29-32 Protein denotes CD4
T28597 0-5 Protein denotes IL-10
R15387 T28597 T28799 causeOf IL-10,mediated
R15389 T28598 T28797 themeOf CD4,production
R15390 T28599 T28800 themeOf CD80,express
R15393 T28602 T28801 themeOf CD28,phosphorylation
R15395 T28604 T28803 themeOf IL-10,defective
R15397 T28605 T28806 causeOf CD28,costimulated
R15399 T28606 T28804 themeOf IFN-γ,production
R15465 T28797 T28798 themeOf production,inhibition
R15466 T28798 T28799 themeOf inhibition,mediated
R15469 T28801 T28802 themeOf phosphorylation,inhibiting
R15471 T28804 T28805 themeOf production,inhibition
R15472 T28804 T28806 themeOf production,costimulated
R15473 T28804 T28805 themeOf production,inhibition
R15474 T28804 T28806 themeOf production,costimulated
R15392 T28600 T28800 themeOf CD86,express
R15398 T28605 T28806 causeOf CD28,costimulated
R15400 T28607 T28804 themeOf IL-2,production

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue Speculation
T30108 0-60 Regulation denotes IL-10-mediated inhibition of CD4+ T-cell cytokine production
T30086 661-715 Positive_regulation denotes of CD28-costimulated production of both IFN-γ and IL-2
T30085 661-715 Positive_regulation denotes of CD28-costimulated production of both IFN-γ and IL-2
T30082 533-594 Negative_regulation denotes This direct effect also may be limited in active RA patients, true
T30059 486-531 Negative_regulation denotes inhibiting CD28 tyrosine phosphorylation [33]
T30028 661-715 Gene_expression denotes of CD28-costimulated production of both IFN-γ and IL-2
T30027 661-715 Gene_expression denotes of CD28-costimulated production of both IFN-γ and IL-2
T30025 0-136 Regulation denotes IL-10-mediated inhibition of CD4+ T-cell cytokine production is principally dependent on its inhibition of macrophage antigen-presenting
T30022 617-715 Negative_regulation denotes T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2
T30021 617-715 Negative_regulation denotes T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2
T30014 107-117 Entity denotes macrophage
T30006 358-379 Entity denotes MHC class II antigens
T29997 261-263 Protein denotes RA
T29992 644-649 Protein denotes IL-10
T29963 240-246 Entity denotes T-cell
T29954 609-611 Protein denotes PB
T29951 617-624 Entity denotes T cells
T29948 104-136 Entity denotes of macrophage antigen-presenting
T29947 664-681 Protein denotes CD28-costimulated
T29943 137-141 Entity denotes cell
T29941 329-333 Protein denotes CD80
T29932 288-294 Protein denotes the ST
T29927 358-370 Protein denotes MHC class II
T29920 711-715 Protein denotes IL-2
T29915 701-706 Protein denotes IFN-γ
T29813 273-294 Entity denotes macrophages in the ST
T29798 338-342 Protein denotes CD86
T29786 497-501 Protein denotes CD28
T29709 0-14 Protein denotes IL-10-mediated
T29755 582-584 Protein denotes RA
T29668 407-412 Protein denotes IL-10
T29747 318-327 Protein denotes cytokines
T29741 26-60 Entity denotes of CD4+ T-cell cytokine production
T29720 497-531 Entity denotes CD28 tyrosine phosphorylation [33]
T29778 459-465 Entity denotes T-cell
T29842 318-353 Entity denotes cytokines, CD80 and CD86 molecules,
T29840 609-615 Protein denotes PB CD4
T29852 442-458 Entity denotes antigen-specific
R15961 T29709 T30108 causeOf IL-10-mediated,IL-10-mediated inhibition of CD4+ T-cell cytokine production
R16011 T29992 T30021 causeOf IL-10,T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2
R16012 T29992 T30022 causeOf IL-10,T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2
R16026 T29915 T30028 themeOf IFN-γ,of CD28-costimulated production of both IFN-γ and IL-2
R16027 T30027 T30021 themeOf of CD28-costimulated production of both IFN-γ and IL-2,T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2
R16028 T30027 T30086 themeOf of CD28-costimulated production of both IFN-γ and IL-2,of CD28-costimulated production of both IFN-γ and IL-2
R16029 T29920 T30027 themeOf IL-2,of CD28-costimulated production of both IFN-γ and IL-2
R16030 T30028 T30022 themeOf of CD28-costimulated production of both IFN-γ and IL-2,T cells showed a defective IL-10 inhibition of CD28-costimulated production of both IFN-γ and IL-2
R16031 T30028 T30085 themeOf of CD28-costimulated production of both IFN-γ and IL-2,of CD28-costimulated production of both IFN-γ and IL-2
R16042 T29947 T30085 causeOf CD28-costimulated,of CD28-costimulated production of both IFN-γ and IL-2
R16044 T29947 T30086 causeOf CD28-costimulated,of CD28-costimulated production of both IFN-γ and IL-2

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T27246 334-337 CC denotes and
T27245 329-333 NNP denotes CD80
T27244 327-328 , denotes ,
T27243 318-327 NNS denotes cytokines
T27242 315-317 IN denotes of
T27241 308-314 NNS denotes levels
T27240 303-307 JJ denotes high
T27239 295-302 VB denotes express
T27238 292-294 NNP denotes ST
T27237 288-291 DT denotes the
T27236 285-287 IN denotes in
T27235 273-284 NNS denotes macrophages
T27234 265-272 IN denotes because
T27233 263-264 , denotes ,
T27232 261-263 NNP denotes RA
T27231 258-260 IN denotes in
T27230 247-257 NN denotes activation
T27229 240-246 NNP denotes T-cell
T27228 237-239 IN denotes of
T27227 232-236 NN denotes site
T27226 228-231 DT denotes the
T27225 225-227 IN denotes at
T27224 214-224 VBN denotes restricted
T27223 211-213 VB denotes be
T27222 208-210 TO denotes to
T27221 200-207 VBN denotes thought
T27220 197-199 VBZ denotes is
T27219 190-196 NN denotes effect
T27218 179-189 JJ denotes inhibitory
T27217 170-178 JJ denotes indirect
T27216 165-169 DT denotes this
T27215 163-164 , denotes ,
T27214 156-163 RB denotes However
T27213 154-155 . denotes .
T27212 153-154 NNP denotes ]
T27211 152-153 CD denotes 1
T27210 151-152 NNP denotes [
T27209 142-150 NN denotes function
T27208 137-141 NN denotes cell
T27207 118-136 JJ denotes antigen-presenting
T27206 107-117 NN denotes macrophage
T27205 104-106 IN denotes of
T27204 93-103 NN denotes inhibition
T27203 89-92 PRP$ denotes its
T27202 86-88 IN denotes on
T27201 76-85 JJ denotes dependent
T27200 64-75 RB denotes principally
T27199 61-63 VBZ denotes is
T27198 50-60 NN denotes production
T27197 41-49 NN denotes cytokine
T27196 34-40 NNP denotes T-cell
T27195 32-33 NNP denotes +
T27194 29-32 NNP denotes CD4
T27193 26-28 IN denotes of
T27192 15-25 NN denotes inhibition
T27191 0-14 JJ denotes IL-10-mediated
T27313 715-716 . denotes .
T27312 711-715 NNP denotes IL-2
T27311 707-710 CC denotes and
T27310 701-706 NNP denotes IFN-γ
T27309 696-700 DT denotes both
T27308 693-695 IN denotes of
T27307 682-692 NN denotes production
T27306 664-681 JJ denotes CD28-costimulated
T27279 530-531 NNP denotes ]
T27278 528-530 CD denotes 33
T27277 527-528 NNP denotes [
T27276 511-526 NN denotes phosphorylation
T27275 502-510 NN denotes tyrosine
T27274 497-501 NNP denotes CD28
T27273 486-496 VBG denotes inhibiting
T27272 483-485 IN denotes by
T27271 466-482 NN denotes unresponsiveness
T27270 459-465 NN denotes T-cell
T27269 442-458 JJ denotes antigen-specific
T27268 438-441 DT denotes the
T27267 431-437 VB denotes induce
T27266 428-430 TO denotes to
T27265 422-427 VBN denotes shown
T27264 417-421 VBN denotes been
T27263 413-416 VBZ denotes has
T27262 407-412 NNP denotes IL-10
T27261 405-406 , denotes ,
T27260 397-405 RB denotes recently
T27259 392-396 RBR denotes More
T27258 390-391 . denotes .
T27257 389-390 NNP denotes ]
T27256 381-389 CD denotes 10,18-20
T27255 380-381 NNP denotes [
T27254 371-379 VBZ denotes antigens
T27253 368-370 NNP denotes II
T27252 362-367 NN denotes class
T27251 358-361 NNP denotes MHC
T27250 354-357 CC denotes and
T27249 352-353 , denotes ,
T27248 343-352 NNS denotes molecules
T27247 338-342 NNP denotes CD86
T27291 585-593 NNS denotes patients
T27290 582-584 NNP denotes RA
T27289 575-581 JJ denotes active
T27288 572-574 IN denotes in
T27287 564-571 VBN denotes limited
T27286 561-563 VB denotes be
T27285 557-560 MD denotes may
T27284 552-556 RB denotes also
T27283 545-551 NN denotes effect
T27282 538-544 JJ denotes direct
T27281 533-537 DT denotes This
T27280 531-532 . denotes .
T27305 661-663 IN denotes of
T27304 650-660 NN denotes inhibition
T27303 644-649 NN denotes IL-10
T27302 634-643 JJ denotes defective
T27301 632-633 DT denotes a
T27300 625-631 VBD denotes showed
T27299 619-624 NNS denotes cells
T27298 617-618 NNP denotes T
T27297 615-616 VBD denotes +
T27296 612-615 NNP denotes CD4
T27295 609-611 NNP denotes PB
T27294 603-608 PRP$ denotes their
T27293 595-602 IN denotes because
T27292 593-594 , denotes ,
R13936 T27192 T27199 nsubj inhibition,is
R13940 T27193 T27192 prep of,inhibition
R13944 T27194 T27198 compound CD4,production
R13948 T27195 T27198 compound +,production
R13952 T27196 T27198 compound T-cell,production
R13953 T27197 T27198 compound cytokine,production
R13956 T27198 T27193 pobj production,of
R13960 T27199 T27199 ROOT is,is
R13963 T27200 T27201 advmod principally,dependent
R13967 T27201 T27199 acomp dependent,is
R13973 T27202 T27201 prep on,dependent
R14020 T27280 T27265 punct .,shown
R14021 T27281 T27283 det This,effect
R14022 T27282 T27283 amod direct,effect
R14024 T27283 T27287 nsubjpass effect,limited
R14025 T27284 T27287 advmod also,limited
R14027 T27285 T27287 aux may,limited
R14028 T27286 T27287 auxpass be,limited
R14029 T27287 T27287 ROOT limited,limited
R14030 T27288 T27287 prep in,limited
R14032 T27289 T27291 amod active,patients
R14033 T27290 T27291 compound RA,patients
R14035 T27291 T27288 pobj patients,in
R14039 T27292 T27287 punct ",",limited
R14040 T27223 T27224 auxpass be,restricted
R14041 T27293 T27300 mark because,showed
R14042 T27294 T27296 poss their,CD4
R14043 T27295 T27296 compound PB,CD4
R14044 T27224 T27221 xcomp restricted,thought
R14045 T27296 T27299 nmod CD4,cells
R14046 T27297 T27299 amod +,cells
R14047 T27225 T27224 prep at,restricted
R14048 T27298 T27299 compound T,cells
R14049 T27299 T27300 nsubj cells,showed
R14050 T27300 T27287 advcl showed,limited
R14051 T27226 T27227 det the,site
R14052 T27227 T27225 pobj site,at
R14053 T27228 T27227 prep of,site
R14054 T27301 T27304 det a,inhibition
R14055 T27302 T27304 amod defective,inhibition
R14056 T27229 T27230 compound T-cell,activation
R14057 T27303 T27304 compound IL-10,inhibition
R14058 T27304 T27300 dobj inhibition,showed
R14059 T27305 T27304 prep of,inhibition
R14060 T27230 T27228 pobj activation,of
R14061 T27306 T27307 amod CD28-costimulated,production
R14062 T27307 T27305 pobj production,of
R14063 T27231 T27230 prep in,activation
R14064 T27308 T27307 prep of,production
R14065 T27309 T27310 preconj both,IFN-γ
R14066 T27310 T27308 pobj IFN-γ,of
R14067 T27232 T27231 pobj RA,in
R14068 T27311 T27310 cc and,IFN-γ
R14069 T27312 T27310 conj IL-2,IFN-γ
R14070 T27313 T27287 punct .,limited
R14073 T27233 T27221 punct ",",thought
R14078 T27234 T27239 mark because,express
R14081 T27235 T27239 nsubj macrophages,express
R14085 T27236 T27235 prep in,macrophages
R14088 T27237 T27238 det the,ST
R14092 T27238 T27236 pobj ST,in
R14095 T27239 T27221 advcl express,thought
R14098 T27240 T27241 amod high,levels
R14102 T27241 T27239 dobj levels,express
R14106 T27242 T27241 prep of,levels
R14110 T27243 T27242 pobj cytokines,of
R14113 T27244 T27243 punct ",",cytokines
R14117 T27245 T27243 conj CD80,cytokines
R14120 T27246 T27245 cc and,CD80
R14128 T27247 T27245 conj CD86,CD80
R14132 T27248 T27245 conj molecules,CD80
R14134 T27249 T27248 punct ",",molecules
R14135 T27250 T27248 cc and,molecules
R14138 T27251 T27253 compound MHC,II
R14143 T27252 T27253 compound class,II
R14146 T27253 T27254 nsubj II,antigens
R14150 T27254 T27248 conj antigens,molecules
R14153 T27255 T27257 compound [,]
R14156 T27256 T27257 compound "10,18-20",]
R14157 T27257 T27254 dobj ],antigens
R14160 T27258 T27254 punct .,antigens
R14163 T27259 T27260 advmod More,recently
R14164 T27260 T27265 advmod recently,shown
R14167 T27261 T27265 punct ",",shown
R14170 T27262 T27265 nsubjpass IL-10,shown
R14176 T27263 T27265 aux has,shown
R14180 T27264 T27265 auxpass been,shown
R14184 T27265 T27265 ROOT shown,shown
R14186 T27266 T27267 aux to,induce
R14187 T27267 T27265 xcomp induce,shown
R14188 T27268 T27271 det the,unresponsiveness
R14191 T27269 T27271 amod antigen-specific,unresponsiveness
R14195 T27270 T27271 compound T-cell,unresponsiveness
R14199 T27271 T27267 dobj unresponsiveness,induce
R14202 T27272 T27267 prep by,induce
R14206 T27273 T27272 pcomp inhibiting,by
R14207 T27274 T27276 nmod CD28,phosphorylation
R14209 T27275 T27276 compound tyrosine,phosphorylation
R14213 T27276 T27277 compound phosphorylation,[
R14218 T27277 T27273 dobj [,inhibiting
R14221 T27278 T27279 nummod 33,]
R14228 T27279 T27277 appos ],[
R13933 T27191 T27192 amod IL-10-mediated,inhibition
R13978 T27203 T27204 poss its,inhibition
R13982 T27204 T27202 pobj inhibition,on
R13986 T27205 T27204 prep of,inhibition
R13990 T27206 T27209 nmod macrophage,function
R13994 T27207 T27209 amod antigen-presenting,function
R13998 T27208 T27209 compound cell,function
R14001 T27209 T27205 pobj function,of
R14006 T27210 T27212 nmod [,]
R14010 T27211 T27212 nummod 1,]
R14013 T27212 T27204 appos ],inhibition
R14017 T27213 T27199 punct .,is
R14018 T27214 T27221 advmod However,thought
R14019 T27215 T27221 punct ",",thought
R14023 T27216 T27219 det this,effect
R14026 T27217 T27219 amod indirect,effect
R14031 T27218 T27219 amod inhibitory,effect
R14034 T27219 T27221 nsubjpass effect,thought
R14036 T27220 T27221 auxpass is,thought
R14037 T27221 T27221 ROOT thought,thought
R14038 T27222 T27224 aux to,restricted

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T23997 669-681 Positive_regulation denotes costimulated
T23996 669-681 Positive_regulation denotes costimulated
T23995 650-660 Negative_regulation denotes inhibition
T23994 650-660 Negative_regulation denotes inhibition
T23993 682-692 Gene_expression denotes production
T23992 682-692 Gene_expression denotes production
T23991 711-715 Protein denotes IL-2
T23990 701-706 Protein denotes IFN-γ
T23989 664-668 Protein denotes CD28
T23988 644-649 Protein denotes IL-10
T23987 612-616 Protein denotes CD4+
T23986 486-496 Negative_regulation denotes inhibiting
T23985 511-526 Phosphorylation denotes phosphorylation
T23984 502-510 Entity denotes tyrosine
T23983 497-501 Protein denotes CD28
T23982 407-412 Protein denotes IL-10
T23981 295-302 Gene_expression denotes express
T23980 295-302 Gene_expression denotes express
T23979 295-302 Gene_expression denotes express
T23978 358-379 Protein denotes MHC class II antigens
T23977 338-352 Protein denotes CD86 molecules
T23976 329-333 Protein denotes CD80
T23975 29-32 Protein denotes CD4
T23974 0-5 Protein denotes IL-10
R11436 T23982 T23986 causeOf IL-10,inhibiting
R11437 T23983 T23985 themeOf CD28,phosphorylation
R11438 T23983 T23984 partOf CD28,tyrosine
R11439 T23984 T23985 Site tyrosine,phosphorylation
R11440 T23985 T23986 themeOf phosphorylation,inhibiting
R11441 T23989 T23996 causeOf CD28,costimulated
R11442 T23989 T23997 causeOf CD28,costimulated
R11443 T23990 T23992 themeOf IFN-γ,production
R11444 T23991 T23993 themeOf IL-2,production
R11445 T23992 T23994 themeOf production,inhibition
R11446 T23992 T23996 themeOf production,costimulated
R11447 T23993 T23995 themeOf production,inhibition
R11448 T23993 T23997 themeOf production,costimulated
R11433 T23976 T23979 themeOf CD80,express
R11434 T23977 T23980 themeOf CD86 molecules,express
R11435 T23978 T23981 themeOf MHC class II antigens,express

test3

Id Subject Object Predicate Lexical cue
T22546 711-715 Protein denotes IL-2
T22545 701-706 Protein denotes IFN-γ
T22544 682-692 Gene_expression denotes production
T22543 669-681 Positive_regulation denotes costimulated
T22542 664-668 Protein denotes CD28
T22541 650-660 Negative_regulation denotes inhibition
T22540 644-649 Protein denotes IL-10
T22539 634-643 Negative_regulation denotes defective
T22538 612-615 Protein denotes CD4
T22537 511-526 Phosphorylation denotes phosphorylation
T22536 497-501 Protein denotes CD28
T22535 486-496 Negative_regulation denotes inhibiting
T22534 407-412 Protein denotes IL-10
T22533 338-342 Protein denotes CD86
T22532 329-333 Protein denotes CD80
T22531 295-302 Gene_expression denotes express
T22530 29-32 Protein denotes CD4
T22529 0-5 Protein denotes IL-10
T22303 711-715 Protein denotes IL-2
T22302 701-706 Protein denotes IFN-γ
T22301 664-668 Protein denotes CD28
T22300 644-649 Protein denotes IL-10
T22299 612-615 Protein denotes CD4
T22298 497-501 Protein denotes CD28
T22297 407-412 Protein denotes IL-10
T22296 338-342 Protein denotes CD86
T22295 329-333 Protein denotes CD80
T22294 29-32 Protein denotes CD4
T22293 0-5 Protein denotes IL-10
R11024 T22532 T22531 themeOf CD80,express
R11025 T22533 T22531 themeOf CD86,express
R11026 T22534 T22535 causeOf IL-10,inhibiting
R11027 T22536 T22537 themeOf CD28,phosphorylation
R11028 T22537 T22535 themeOf phosphorylation,inhibiting
R11029 T22540 T22541 causeOf IL-10,inhibition
R11030 T22541 T22539 themeOf inhibition,defective
R11031 T22542 T22543 causeOf CD28,costimulated
R11032 T22543 T22541 themeOf costimulated,inhibition
R11033 T22544 T22543 themeOf production,costimulated
R11034 T22545 T22544 themeOf IFN-γ,production
R11035 T22546 T22544 themeOf IL-2,production

testone

Id Subject Object Predicate Lexical cue
T21771 711-715 Protein denotes IL-2
T21770 701-706 Protein denotes IFN-γ
T21769 664-668 Protein denotes CD28
T21768 644-649 Protein denotes IL-10
T21767 612-615 Protein denotes CD4
T21766 497-501 Protein denotes CD28
T21765 407-412 Protein denotes IL-10
T21764 338-342 Protein denotes CD86
T21763 329-333 Protein denotes CD80
T21762 29-32 Protein denotes CD4
T21761 0-5 Protein denotes IL-10
T21956 682-692 Gene_expression denotes production
T21955 669-681 Positive_regulation denotes costimulated
T21954 650-660 Negative_regulation denotes inhibition
T21953 634-643 Negative_regulation denotes defective
T21952 295-302 Gene_expression denotes express
R10862 T21763 T21952 themeOf CD80,express
R10863 T21764 T21952 themeOf CD86,express
R10864 T21768 T21954 causeOf IL-10,inhibition
R10865 T21768 T21953 themeOf IL-10,defective
R10866 T21769 T21955 causeOf CD28,costimulated
R10867 T21770 T21956 themeOf IFN-γ,production
R10868 T21771 T21956 themeOf IL-2,production
R10959 T21955 T21954 themeOf costimulated,inhibition
R10960 T21956 T21955 themeOf production,costimulated