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PMC:1064873 / 19633-22077 JSONTXT

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LappsTest

Id Subject Object Predicate Lexical cue
T17298 1656-1661 Protein denotes STAT1
T17297 1616-1621 Protein denotes STAT3
T17296 1582-1587 Protein denotes STAT1
T17295 1557-1561 Protein denotes IL-6
T17294 1484-1489 Protein denotes STAT1
T17293 1398-1430 Protein denotes dominant STAT3-activating factor
T17292 1386-1390 Protein denotes IL-6
T17291 1333-1337 Protein denotes IL-6
T17290 1274-1279 Protein denotes STAT3
T17289 1258-1263 Protein denotes STAT1
T17288 1244-1249 Protein denotes STAT3
T17287 1128-1132 Protein denotes STAT
T17286 1071-1102 Protein denotes neutralizing anti-IL-6 antibody
T17285 958-962 Protein denotes CD4+
T17284 875-879 Protein denotes CD4+
T17283 860-864 Protein denotes IL-6
T17282 821-826 Protein denotes STAT3
T17281 811-816 Protein denotes STAT1
T17280 775-780 Protein denotes IL-10
T17279 740-745 Protein denotes STAT3
T17278 674-678 Protein denotes IL-6
T17277 635-639 Protein denotes CD4+
T17276 500-504 Protein denotes IL-6
T17275 461-466 Protein denotes STAT3
T17274 375-379 Protein denotes IL-6
T17273 280-303 Protein denotes epidermal growth factor
T17272 244-274 Protein denotes platelet-derived growth factor
T17271 184-188 Protein denotes IL-6
T17270 158-169 Protein denotes IL-6 family
T17269 90-95 Protein denotes STAT3
T17268 77-81 Protein denotes CD4+
T17267 54-59 Protein denotes IL-10
T17266 14-19 Protein denotes STAT3
T17265 0-4 Protein denotes IL-6
T17311 2428-2435 Protein denotes RA CD4+
T17310 2419-2424 Protein denotes IL-10
T17309 2355-2360 Protein denotes STAT3
T17308 2309-2313 Protein denotes IL-6
T17307 2229-2234 Protein denotes IL-10
T17306 2184-2188 Protein denotes IL-6
T17305 2046-2050 Protein denotes IL-6
T17304 1913-1916 Protein denotes CD3
T17303 1881-1885 Protein denotes CD4+
T17302 1855-1859 Protein denotes IL-6
T17301 1796-1800 Protein denotes CD4+
T17300 1759-1764 Protein denotes IL-10
T17299 1725-1729 Protein denotes IL-6

2_test

Id Subject Object Predicate Lexical cue
15535835-12039028-4156895 327-328 12039028 denotes 4
15535835-7869026-4156896 489-491 7869026 denotes 31
15535835-9182920-4156897 587-589 9182920 denotes 27
15535835-12039028-4156898 947-948 12039028 denotes 4

biosemtest

Id Subject Object Predicate Lexical cue
T18007 1269-1273 UMLS/C0323983 denotes this
T18006 163-169 UMLS/C1704727 denotes family
T18005 2126-2136 UMLS/C1548180 denotes duction (F
T18004 2014-2024 UMLS/C1548180 denotes oduction w
T18003 1783-1793 UMLS/C1548180 denotes roduction
T18002 1922-1926 UMLS/C1332709 denotes D28
T18001 2283-2293 UMLS/C0205322 denotes sistent ex
T18000 612-622 UMLS/C0205322 denotes persistent
T17999 1106-1113 UMLS/C2587213 denotes control
T17998 2164-2168 UMLS/C1299351 denotes h co
T17997 1532-1538 UMLS/C1299351 denotes higher
T17996 651-655 UMLS/C1299351 denotes high
T17995 2383-2393 UMLS/C0237834 denotes istance to
T17994 761-771 UMLS/C0237834 denotes resistance
T17993 1736-1744 UMLS/C1260953 denotes suppress
T17992 1973-1978 UMLS/C0439275 denotes g/ml
T17991 1850-1855 UMLS/C0439275 denotes g/ml
T17990 580-585 UMLS/C0439275 denotes ng/ml
T17989 1114-1122 UMLS/C0003241 denotes antibody
T17988 1094-1102 UMLS/C0003241 denotes antibody
T17987 1875-1881 UMLS/C0205307 denotes ormal
T17986 951-957 UMLS/C0205307 denotes Normal
T17985 868-874 UMLS/C0205307 denotes normal
T17984 70-76 UMLS/C0205307 denotes normal
T17983 1476-1480 UMLS/C0332268 denotes lack
T17982 2317-2320 UMLS/C0337876 denotes ha
T17981 1672-1675 UMLS/C0337876 denotes may
T17980 1562-1565 UMLS/C0337876 denotes may
T17979 1811-1816 UMLS/C0231290 denotes fter
T17978 1992-1997 UMLS/C0439227 denotes ours,
T17977 1868-1873 UMLS/C0439227 denotes ours,
T17976 1431-1440 UMLS/C0332256 denotes contained
T17975 1022-1032 UMLS/C0332256 denotes containing
T17974 1364-1371 UMLS/C1546471 denotes results
T17973 163-169 UMLS/C1555907 denotes family
T17972 2306-2311 UMLS/C1151254 denotes um IL
T17971 1693-1698 UMLS/C1151254 denotes serum
T17970 1507-1512 UMLS/C1151254 denotes serum
T17969 1444-1448 UMLS/C1151254 denotes sera
T17968 1191-1196 UMLS/C1151254 denotes serum
T17967 1037-1042 UMLS/C1151254 denotes serum
T17966 525-529 UMLS/C1151254 denotes sera
T17965 1007-1021 UMLS/C0010454 denotes culture medium
T17964 1922-1926 UMLS/C1426202 denotes D28
T17963 1703-1707 UMLS/C0332282 denotes next
T17962 2069-2081 UMLS/C0007634 denotes rmal cells r
T17961 1254-1257 UMLS/C1518422 denotes not
T17960 894-897 UMLS/C1518422 denotes not
T17959 190-195 UMLS/C0537670 denotes IL-11
T17958 998-1001 UMLS/C0439232 denotes min
T17957 1106-1113 UMLS/C0332298 denotes control
T17956 1462-1470 UMLS/C1705908 denotes patients
T17955 1058-1066 UMLS/C1705908 denotes patients
T17954 543-551 UMLS/C1705908 denotes patients
T17953 1431-1440 UMLS/C2700400 denotes contained
T17952 1022-1032 UMLS/C2700400 denotes containing
T17951 2345-2354 UMLS/C0205263 denotes uction of
T17950 1209-1215 UMLS/C0205263 denotes induce
T17949 426-433 UMLS/C0205263 denotes induces
T17948 308-319 UMLS/C0332287 denotes addition to
T17947 2164-2168 UMLS/C0205250 denotes h co
T17942 1662-1671 UMLS/C1710082 denotes signaling
T17941 1431-1440 UMLS/C1549781 denotes contained
T17940 1022-1032 UMLS/C1549781 denotes containing
T17939 1128-1132 UMLS/C1366753 denotes STAT
T17938 1315-1329 UMLS/C1446680 denotes neutralization
T17937 564-572 UMLS/C0442726 denotes detected
T17936 163-169 UMLS/C1552262 denotes family
T17935 1875-1881 UMLS/C2347086 denotes ormal
T17934 951-957 UMLS/C2347086 denotes Normal
T17933 868-874 UMLS/C2347086 denotes normal
T17932 70-76 UMLS/C2347086 denotes normal
T17931 2169-2183 UMLS/C0086045 denotes centrations of
T17930 1539-1553 UMLS/C0086045 denotes concentrations
T17929 656-670 UMLS/C0086045 denotes concentrations
T17928 1315-1329 UMLS/C1578828 denotes neutralization
T17927 909-918 UMLS/C0680240 denotes agreement
T17926 1679-1686 UMLS/C0449450 denotes present
T17925 2345-2354 UMLS/C1621983 denotes uction of
T17924 2105-2115 UMLS/C1628982 denotes hibition o
T17923 781-791 UMLS/C1628982 denotes inhibition
T17922 344-351 UMLS/C1705923 denotes studies
T17921 730-739 UMLS/C0443318 denotes sustained
T17920 2198-2206 UMLS/C1709059 denotes ulate T-
T17919 2358-2363 UMLS/C1367307 denotes T3 ac
T17918 1616-1621 UMLS/C1367307 denotes STAT3
T17917 1407-1412 UMLS/C1367307 denotes STAT3
T17916 1274-1279 UMLS/C1367307 denotes STAT3
T17915 1244-1249 UMLS/C1367307 denotes STAT3
T17914 821-826 UMLS/C1367307 denotes STAT3
T17913 740-745 UMLS/C1367307 denotes STAT3
T17912 461-466 UMLS/C1367307 denotes STAT3
T17911 90-95 UMLS/C1367307 denotes STAT3
T17910 14-19 UMLS/C1367307 denotes STAT3
T17909 933-945 UMLS/C0700325 denotes observations
T17908 1875-1881 UMLS/C0439166 denotes ormal
T17907 951-957 UMLS/C0439166 denotes Normal
T17906 868-874 UMLS/C0439166 denotes normal
T17905 70-76 UMLS/C0439166 denotes normal
T17904 280-303 UMLS/C1749410 denotes epidermal growth factor
T17903 1338-1346 UMLS/C0439167 denotes activity
T17902 1106-1113 UMLS/C0243148 denotes control
T17901 1569-1577 UMLS/C1514873 denotes required
T17900 889-893 UMLS/C1511726 denotes data
T17899 197-223 UP/P09056 denotes leukemia inhibitory factor
T17898 197-223 UP/P15018 denotes leukemia inhibitory factor
T17897 2192-2197 UMLS/C0344312 denotes ld mo
T17896 1730-1735 UMLS/C0344312 denotes could
T17895 163-169 UMLS/C2700055 denotes family
T17894 1656-1661 UP/P42224 denotes STAT1
T17893 1582-1587 UP/P42224 denotes STAT1
T17892 1484-1489 UP/P42224 denotes STAT1
T17891 1258-1263 UP/P42224 denotes STAT1
T17890 811-816 UP/P42224 denotes STAT1
T17889 933-945 UMLS/C0302523 denotes observations
T17888 686-703 UMLS/C0005775 denotes blood circulation
T17887 2306-2311 UMLS/C1550100 denotes um IL
T17886 1693-1698 UMLS/C1550100 denotes serum
T17885 1507-1512 UMLS/C1550100 denotes serum
T17884 1444-1448 UMLS/C1550100 denotes sera
T17883 1191-1196 UMLS/C1550100 denotes serum
T17882 1037-1042 UMLS/C1550100 denotes serum
T17881 525-529 UMLS/C1550100 denotes sera
T17880 1216-1240 UMLS/C1519726 denotes tyrosine phosphorylation
T17879 1662-1671 UMLS/C0037083 denotes signaling
T17878 1960-1967 UMLS/C1689985 denotes bsence
T17877 1315-1329 UMLS/C1550107 denotes neutralization
T17876 2192-2197 UMLS/C0006823 denotes ld mo
T17875 1730-1735 UMLS/C0006823 denotes could
T17874 1703-1707 UMLS/C1552851 denotes next
T17873 2198-2206 UMLS/C0443264 denotes ulate T-
T17872 1462-1470 UMLS/C1550655 denotes patients
T17871 1058-1066 UMLS/C1550655 denotes patients
T17870 543-551 UMLS/C1550655 denotes patients
T17869 981-990 UMLS/C1439852 denotes incubated
T17868 131-145 UP/Q776B5 denotes growth factors
T17867 2069-2081 UMLS/C1268443 denotes rmal cells r
T17866 131-145 UP/Q86607 denotes growth factors
T17865 2239-2244 UMLS/C1515187 denotes en to
T17864 1106-1113 UMLS/C1547100 denotes control
T17863 2328-2332 UMLS/C1704326 denotes e in
T17862 2358-2363 UMLS/C0253050 denotes T3 ac
T17861 1616-1621 UMLS/C0253050 denotes STAT3
T17860 1407-1412 UMLS/C0253050 denotes STAT3
T17859 1274-1279 UMLS/C0253050 denotes STAT3
T17858 1244-1249 UMLS/C0253050 denotes STAT3
T17857 821-826 UMLS/C0253050 denotes STAT3
T17856 740-745 UMLS/C0253050 denotes STAT3
T17855 461-466 UMLS/C0253050 denotes STAT3
T17854 90-95 UMLS/C0253050 denotes STAT3
T17853 14-19 UMLS/C0253050 denotes STAT3
T17852 131-145 UP/Q8V307 denotes growth factors
T17851 2164-2168 UMLS/C1522410 denotes h co
T17850 1532-1538 UMLS/C1522410 denotes higher
T17849 651-655 UMLS/C1522410 denotes high
T17848 197-223 UP/P17777 denotes leukemia inhibitory factor
T17847 1992-1997 UMLS/C0564385 denotes ours,
T17846 1868-1873 UMLS/C0564385 denotes ours,
T17845 197-223 UMLS/C1761537 denotes leukemia inhibitory factor
T17844 406-420 UMLS/C0039097 denotes synovial fluid
T17843 2029-2037 UMLS/C0079809 denotes asured b
T17842 1875-1881 UMLS/C1873497 denotes ormal
T17841 951-957 UMLS/C1873497 denotes Normal
T17840 868-874 UMLS/C1873497 denotes normal
T17839 70-76 UMLS/C1873497 denotes normal
T17838 2283-2293 UMLS/C0546816 denotes sistent ex
T17837 612-622 UMLS/C0546816 denotes persistent
T17836 1338-1346 UMLS/C0441655 denotes activity
T17835 2105-2115 UMLS/C0021467 denotes hibition o
T17834 781-791 UMLS/C0021467 denotes inhibition
T17833 2401-2411 UMLS/C0021469 denotes ibitory ef
T17832 2105-2115 UMLS/C0021469 denotes hibition o
T17831 1768-1775 UMLS/C0021469 denotes inhibit
T17830 781-791 UMLS/C0021469 denotes inhibition
T17829 244-274 UMLS/C1761525 denotes platelet-derived growth factor
T17828 1948-1956 UMLS/C0150312 denotes resence
T17827 1679-1686 UMLS/C0150312 denotes present
T17826 1527-1531 UMLS/C0439064 denotes much
T17825 112-116 UMLS/C0439064 denotes many
T17824 1914-1917 UMLS/C2698592 denotes D3
T17823 1114-1122 UMLS/C1621287 denotes antibody
T17822 1094-1102 UMLS/C1621287 denotes antibody
T17821 2138-2141 UMLS/C0349966 denotes . 5
T17820 1348-1351 UMLS/C0349966 denotes Fig
T17819 1452-1458 UMLS/C1553875 denotes active
T17818 1048-1054 UMLS/C1553875 denotes active
T17817 795-801 UMLS/C1553875 denotes active
T17816 533-539 UMLS/C1553875 denotes active
T17815 1703-1707 UMLS/C1883708 denotes next
T17814 2053-2065 UMLS/C1550147 denotes etreatment o
T17813 344-351 UMLS/C0557651 denotes studies
T17812 2207-2213 UMLS/C0039194 denotes ell re
T17811 1887-1894 UMLS/C0039194 denotes cells
T17810 1802-1809 UMLS/C0039194 denotes cells.
T17809 963-970 UMLS/C0039194 denotes T cells
T17808 880-887 UMLS/C0039194 denotes T cells
T17807 640-647 UMLS/C0039194 denotes T cells
T17806 82-89 UMLS/C0039194 denotes T cells
T17805 229-241 UMLS/C1335093 denotes oncostatin M
T17804 2328-2332 UMLS/C1705809 denotes e in
T17803 229-241 UMLS/C0069535 denotes oncostatin M
T17802 2328-2332 UMLS/C1705812 denotes e in
T17801 2328-2332 UMLS/C1705810 denotes e in
T17800 2328-2332 UMLS/C1705811 denotes e in
T17799 131-145 UP/P08441 denotes growth factors
T17798 2239-2244 UMLS/C1883727 denotes en to
T17797 1922-1926 UMLS/C0075747 denotes D28
T17796 20-50 UMLS/C1519062 denotes phosphorylation and inhibition
T17795 1602-1610 UMLS/C1707455 denotes compared
T17794 244-274 UMLS/C0032200 denotes platelet-derived growth factor
T17793 1106-1113 UMLS/C1550141 denotes control
T17792 2306-2311 UMLS/C0229671 denotes um IL
T17791 1693-1698 UMLS/C0229671 denotes serum
T17790 1507-1512 UMLS/C0229671 denotes serum
T17789 1444-1448 UMLS/C0229671 denotes sera
T17788 1191-1196 UMLS/C0229671 denotes serum
T17787 1037-1042 UMLS/C0229671 denotes serum
T17786 525-529 UMLS/C0229671 denotes sera
T17785 2169-2183 UMLS/C1446561 denotes centrations of
T17784 1539-1553 UMLS/C1446561 denotes concentrations
T17783 656-670 UMLS/C1446561 denotes concentrations
T17782 1128-1132 UMLS/C1548425 denotes STAT
T17781 190-195 UMLS/C1149216 denotes IL-11
T17780 2422-2427 UMLS/C1149215 denotes 10 in
T17779 2232-2237 UMLS/C1149215 denotes 10. T
T17778 2090-2095 UMLS/C1149215 denotes -10-m
T17777 1979-1984 UMLS/C1149215 denotes L-10
T17776 1759-1764 UMLS/C1149215 denotes IL-10
T17775 775-780 UMLS/C1149215 denotes IL-10
T17774 320-325 UMLS/C1149215 denotes IL-10
T17773 54-59 UMLS/C1149215 denotes IL-10
T17772 2306-2311 UMLS/C1546774 denotes um IL
T17771 1693-1698 UMLS/C1546774 denotes serum
T17770 1507-1512 UMLS/C1546774 denotes serum
T17769 1444-1448 UMLS/C1546774 denotes sera
T17768 1191-1196 UMLS/C1546774 denotes serum
T17767 1037-1042 UMLS/C1546774 denotes serum
T17766 525-529 UMLS/C1546774 denotes sera
T17765 2328-2332 UMLS/C0035820 denotes e in
T17764 2029-2037 UMLS/C1879489 denotes asured b
T17763 2383-2393 UMLS/C1522618 denotes istance to
T17762 761-771 UMLS/C1522618 denotes resistance
T17761 933-945 UMLS/C1554188 denotes observations
T17760 998-1001 UMLS/C1552937 denotes min
T17759 2261-2269 UMLS/C2607943 denotes dings su
T17758 2312-2316 UMLS/C1149241 denotes 6 ma
T17757 2187-2191 UMLS/C1149241 denotes 6 co
T17756 2048-2052 UMLS/C1149241 denotes -6 p
T17755 1856-1860 UMLS/C1149241 denotes L-6
T17754 1725-1729 UMLS/C1149241 denotes IL-6
T17753 1557-1561 UMLS/C1149241 denotes IL-6
T17752 1386-1390 UMLS/C1149241 denotes IL-6
T17751 1333-1337 UMLS/C1149241 denotes IL-6
T17750 860-864 UMLS/C1149241 denotes IL-6
T17749 674-678 UMLS/C1149241 denotes IL-6
T17748 500-504 UMLS/C1149241 denotes IL-6
T17747 375-379 UMLS/C1149241 denotes IL-6
T17746 184-188 UMLS/C1149241 denotes IL-6
T17745 158-162 UMLS/C1149241 denotes IL-6
T17744 0-4 UMLS/C1149241 denotes IL-6
T17743 1656-1661 UMLS/C1335872 denotes STAT1
T17742 1582-1587 UMLS/C1335872 denotes STAT1
T17741 1484-1489 UMLS/C1335872 denotes STAT1
T17740 1258-1263 UMLS/C1335872 denotes STAT1
T17739 811-816 UMLS/C1335872 denotes STAT1
T17738 2317-2320 UMLS/C0454788 denotes ha
T17737 1672-1675 UMLS/C0454788 denotes may
T17736 1562-1565 UMLS/C0454788 denotes may
T17735 2412-2418 UMLS/C2348382 denotes ect of
T17734 1749-1755 UMLS/C2348382 denotes effect
T17733 60-66 UMLS/C2348382 denotes effect
T17732 1642-1652 UMLS/C1999216 denotes inhibitors
T17731 564-572 UMLS/C1511790 denotes detected
T17730 2364-2374 UMLS/C1879547 denotes ivation an
T17729 1622-1632 UMLS/C1879547 denotes activation
T17728 1588-1598 UMLS/C1879547 denotes activation
T17727 1490-1500 UMLS/C1879547 denotes activation
T17664 1532-1538 UMLS/C1561957 denotes higher
T17663 651-655 UMLS/C1561957 denotes high
T17662 2164-2168 UMLS/C1561958 denotes h co
T17661 1532-1538 UMLS/C1561958 denotes higher
T17660 651-655 UMLS/C1561958 denotes high
T17659 2312-2316 UMLS/C0021760 denotes 6 ma
T17658 2187-2191 UMLS/C0021760 denotes 6 co
T17657 2048-2052 UMLS/C0021760 denotes -6 p
T17656 1856-1860 UMLS/C0021760 denotes L-6
T17655 1725-1729 UMLS/C0021760 denotes IL-6
T17654 1557-1561 UMLS/C0021760 denotes IL-6
T17653 1386-1390 UMLS/C0021760 denotes IL-6
T17652 1333-1337 UMLS/C0021760 denotes IL-6
T17651 860-864 UMLS/C0021760 denotes IL-6
T17650 674-678 UMLS/C0021760 denotes IL-6
T17649 500-504 UMLS/C0021760 denotes IL-6
T17648 375-379 UMLS/C0021760 denotes IL-6
T17647 184-188 UMLS/C0021760 denotes IL-6
T17646 158-162 UMLS/C0021760 denotes IL-6
T17645 0-4 UMLS/C0021760 denotes IL-6
T17644 1165-1186 UMLS/C0949466 denotes western blot analysis
T17643 1398-1406 UMLS/C1527180 denotes dominant
T17642 1462-1470 UMLS/C0030705 denotes patients
T17641 1058-1066 UMLS/C0030705 denotes patients
T17640 543-551 UMLS/C0030705 denotes patients
T17639 1948-1956 UMLS/C0392148 denotes resence
T17638 2312-2316 UMLS/C1334122 denotes 6 ma
T17637 2187-2191 UMLS/C1334122 denotes 6 co
T17636 2048-2052 UMLS/C1334122 denotes -6 p
T17635 1856-1860 UMLS/C1334122 denotes L-6
T17634 1725-1729 UMLS/C1334122 denotes IL-6
T17633 1557-1561 UMLS/C1334122 denotes IL-6
T17632 1386-1390 UMLS/C1334122 denotes IL-6
T17631 1333-1337 UMLS/C1334122 denotes IL-6
T17630 860-864 UMLS/C1334122 denotes IL-6
T17629 674-678 UMLS/C1334122 denotes IL-6
T17628 500-504 UMLS/C1334122 denotes IL-6
T17627 375-379 UMLS/C1334122 denotes IL-6
T17626 184-188 UMLS/C1334122 denotes IL-6
T17625 158-162 UMLS/C1334122 denotes IL-6
T17624 0-4 UMLS/C1334122 denotes IL-6
T17623 1128-1132 UMLS/C1335960 denotes STAT
T17622 1569-1577 UMLS/C1556066 denotes required
T17621 1201-1205 UMLS/C1299581 denotes able
T17620 1462-1470 UMLS/C1578479 denotes patients
T17619 1058-1066 UMLS/C1578479 denotes patients
T17618 543-551 UMLS/C1578479 denotes patients
T17617 1128-1132 UMLS/C1420304 denotes STAT
T17616 1338-1346 UMLS/C1561536 denotes activity
T17615 1462-1470 UMLS/C1578483 denotes patients
T17614 1058-1066 UMLS/C1578483 denotes patients
T17613 543-551 UMLS/C1578483 denotes patients
T17612 1462-1470 UMLS/C1578480 denotes patients
T17611 1058-1066 UMLS/C1578480 denotes patients
T17610 543-551 UMLS/C1578480 denotes patients
T17609 1462-1470 UMLS/C1578481 denotes patients
T17608 1058-1066 UMLS/C1578481 denotes patients
T17607 543-551 UMLS/C1578481 denotes patients
T17606 1462-1470 UMLS/C1578486 denotes patients
T17605 1058-1066 UMLS/C1578486 denotes patients
T17604 543-551 UMLS/C1578486 denotes patients
T17603 1914-1917 UMLS/C0108779 denotes D3
T17602 1462-1470 UMLS/C1578484 denotes patients
T17601 1058-1066 UMLS/C1578484 denotes patients
T17600 543-551 UMLS/C1578484 denotes patients
T17599 1462-1470 UMLS/C1578485 denotes patients
T17598 1058-1066 UMLS/C1578485 denotes patients
T17597 543-551 UMLS/C1578485 denotes patients
T17596 1114-1122 UMLS/C0021027 denotes antibody
T17595 1094-1102 UMLS/C0021027 denotes antibody
T17594 131-145 UP/Q6RZT5 denotes growth factors
T17593 1960-1967 UMLS/C0332197 denotes bsence
T17592 1656-1661 UP/P42229 denotes STAT1
T17591 1582-1587 UP/P42229 denotes STAT1
T17590 1484-1489 UP/P42229 denotes STAT1
T17589 1258-1263 UP/P42229 denotes STAT1
T17588 811-816 UP/P42229 denotes STAT1
T17587 190-195 UMLS/C0083031 denotes IL-11
T17586 1452-1458 UMLS/C1561511 denotes active
T17585 1048-1054 UMLS/C1561511 denotes active
T17584 795-801 UMLS/C1561511 denotes active
T17583 533-539 UMLS/C1561511 denotes active
T17582 1642-1652 UMLS/C0243077 denotes inhibitors
T17581 1452-1458 UMLS/C1561512 denotes active
T17580 1048-1054 UMLS/C1561512 denotes active
T17579 795-801 UMLS/C1561512 denotes active
T17578 533-539 UMLS/C1561512 denotes active
T17577 1452-1458 UMLS/C1561513 denotes active
T17576 1048-1054 UMLS/C1561513 denotes active
T17575 795-801 UMLS/C1561513 denotes active
T17574 533-539 UMLS/C1561513 denotes active
T17573 2148-2158 UMLS/C1444656 denotes icating th
T17572 1372-1380 UMLS/C1444656 denotes indicate
T17571 131-145 UP/P20494 denotes growth factors
T17570 623-631 UMLS/C1704625 denotes exposure
T17569 553-563 UMLS/C0332183 denotes frequently
T17568 924-932 UMLS/C0205156 denotes previous
T17567 335-343 UMLS/C0205156 denotes previous
T17566 197-223 UMLS/C0125606 denotes leukemia inhibitory factor
T17565 1960-1967 UMLS/C0424530 denotes bsence
T17564 387-392 UMLS/C0205164 denotes major
T17563 197-223 UP/Q27956 denotes leukemia inhibitory factor
T17562 1569-1577 UMLS/C1546857 denotes required
T17561 933-945 UMLS/C1548358 denotes observations
T17560 2294-2305 UMLS/C0332157 denotes osure to se
T17559 623-631 UMLS/C0332157 denotes exposure
T17558 623-631 UMLS/C0274281 denotes exposure
T17557 344-351 UMLS/C1880229 denotes studies
T17556 470-487 UMLS/C0806987 denotes mononuclear cells
T17555 1452-1458 UMLS/C0205177 denotes active
T17554 1048-1054 UMLS/C0205177 denotes active
T17553 795-801 UMLS/C0205177 denotes active
T17552 533-539 UMLS/C0205177 denotes active
T17551 197-223 UP/O62728 denotes leukemia inhibitory factor
T17550 933-945 UMLS/C0557985 denotes observations
T17549 2383-2393 UMLS/C0683598 denotes istance to
T17548 761-771 UMLS/C0683598 denotes resistance
T17547 1452-1458 UMLS/C2347179 denotes active
T17546 1048-1054 UMLS/C2347179 denotes active
T17545 795-801 UMLS/C2347179 denotes active
T17544 533-539 UMLS/C2347179 denotes active
T17543 1353-1355 UMLS/C1553637 denotes 5a
T17542 2422-2427 UMLS/C0085295 denotes 10 in
T17541 2232-2237 UMLS/C0085295 denotes 10. T
T17540 2090-2095 UMLS/C0085295 denotes -10-m
T17539 1979-1984 UMLS/C0085295 denotes L-10
T17538 1759-1764 UMLS/C0085295 denotes IL-10
T17537 775-780 UMLS/C0085295 denotes IL-10
T17536 320-325 UMLS/C0085295 denotes IL-10
T17535 54-59 UMLS/C0085295 denotes IL-10
T17534 933-945 UMLS/C1964257 denotes observations
T17533 2082-2089 UMLS/C0392756 denotes duced I
T17532 2270-2277 UMLS/C1705535 denotes gest th
T17531 1513-1521 UMLS/C1705535 denotes suggests
T17530 131-145 UP/O57166 denotes growth factors
T17529 1875-1881 UMLS/C1704701 denotes ormal
T17528 951-957 UMLS/C1704701 denotes Normal
T17527 868-874 UMLS/C1704701 denotes normal
T17526 70-76 UMLS/C1704701 denotes normal
T17525 131-145 UMLS/C0018284 denotes growth factors
T17524 1250-1253 UMLS/C0005341 denotes but
T17523 331-334 UMLS/C0005341 denotes but
T17522 2394-2396 UMLS/C0319022 denotes th
T17521 2229-2231 UMLS/C0319022 denotes IL
T17520 1765-1767 UMLS/C0319022 denotes to
T17519 1206-1208 UMLS/C0319022 denotes to
T17518 772-774 UMLS/C0319022 denotes to
T17517 648-650 UMLS/C0319022 denotes to
T17516 2096-2104 UMLS/C0127400 denotes diated i
T17515 5-13 UMLS/C0127400 denotes mediated
T17514 2096-2104 UMLS/C0086597 denotes diated i
T17513 5-13 UMLS/C0086597 denotes mediated
T17512 2029-2037 UMLS/C0444706 denotes asured b
T17511 1708-1716 UMLS/C0332128 denotes examined
T17510 1153-1161 UMLS/C0332128 denotes examined
T17509 595-603 UMLS/C0332128 denotes examined
T17508 513-521 UMLS/C2346714 denotes abundant
T17507 280-303 UMLS/C0242275 denotes epidermal growth factor
T17506 261-289 UMLS/C0242275 denotes growth factor, and epidermal
T17505 1875-1881 UMLS/C1550457 denotes ormal
T17504 951-957 UMLS/C1550457 denotes Normal
T17503 868-874 UMLS/C1550457 denotes normal
T17502 70-76 UMLS/C1550457 denotes normal
T17501 131-145 UP/P08072 denotes growth factors
T17500 933-945 UMLS/C0941132 denotes observations
T17499 1569-1577 UMLS/C1619636 denotes required
T17498 1452-1458 UMLS/C1561510 denotes active
T17497 1048-1054 UMLS/C1561510 denotes active
T17496 795-801 UMLS/C1561510 denotes active
T17495 533-539 UMLS/C1561510 denotes active
T17494 131-145 UP/P33804 denotes growth factors
T17493 1452-1458 UMLS/C1561509 denotes active
T17492 1048-1054 UMLS/C1561509 denotes active
T17491 795-801 UMLS/C1561509 denotes active
T17490 533-539 UMLS/C1561509 denotes active
T17489 1452-1458 UMLS/C1561508 denotes active
T17488 1048-1054 UMLS/C1561508 denotes active
T17487 795-801 UMLS/C1561508 denotes active
T17486 533-539 UMLS/C1561508 denotes active
T17485 1452-1458 UMLS/C1561507 denotes active
T17484 1048-1054 UMLS/C1561507 denotes active
T17483 795-801 UMLS/C1561507 denotes active
T17482 533-539 UMLS/C1561507 denotes active
T17481 344-351 UMLS/C0947630 denotes studies
T17946 1532-1538 UMLS/C0205250 denotes higher
T17945 651-655 UMLS/C0205250 denotes high
T17944 1364-1371 UMLS/C0332294 denotes results
T17943 1364-1371 UMLS/C1274040 denotes results
T17480 1133-1148 UMLS/C0031715 denotes phosphorylation
T17479 827-842 UMLS/C0031715 denotes phosphorylation
T17478 163-169 UMLS/C1563343 denotes family
T17477 1875-1881 UMLS/C1551394 denotes ormal
T17476 951-957 UMLS/C1551394 denotes Normal
T17475 868-874 UMLS/C1551394 denotes normal
T17474 70-76 UMLS/C1551394 denotes normal
T17473 1452-1458 UMLS/C1547419 denotes active
T17472 1048-1054 UMLS/C1547419 denotes active
T17471 795-801 UMLS/C1547419 denotes active
T17470 533-539 UMLS/C1547419 denotes active
T17469 173-182 UMLS/C0079189 denotes cytokines
T17468 117-126 UMLS/C0079189 denotes cytokines
T17467 131-145 UP/Q9JFH4 denotes growth factors
T17466 1106-1113 UMLS/C1882979 denotes control
T17465 924-932 UMLS/C1552607 denotes previous
T17464 335-343 UMLS/C1552607 denotes previous
T17726 1413-1423 UMLS/C1879547 denotes activating
T17725 1280-1290 UMLS/C1879547 denotes activation
T17724 847-856 UMLS/C1879547 denotes activated
T17723 746-756 UMLS/C1879547 denotes activation
T17722 447-457 UMLS/C1879547 denotes activation
T17721 99-108 UMLS/C1879547 denotes activated
T17720 1364-1371 UMLS/C1280519 denotes results
T17719 163-169 UMLS/C0015576 denotes family
T17718 344-351 UMLS/C0008972 denotes studies
T17717 1201-1205 UMLS/C0085732 denotes able
T17716 344-351 UMLS/C0008976 denotes studies
T17715 2312-2316 UMLS/C1527132 denotes 6 ma
T17714 2187-2191 UMLS/C1527132 denotes 6 co
T17713 2048-2052 UMLS/C1527132 denotes -6 p
T17712 1856-1860 UMLS/C1527132 denotes L-6
T17711 1725-1729 UMLS/C1527132 denotes IL-6
T17710 1557-1561 UMLS/C1527132 denotes IL-6
T17709 1386-1390 UMLS/C1527132 denotes IL-6
T17708 1333-1337 UMLS/C1527132 denotes IL-6
T17707 860-864 UMLS/C1527132 denotes IL-6
T17706 674-678 UMLS/C1527132 denotes IL-6
T17705 500-504 UMLS/C1527132 denotes IL-6
T17704 375-379 UMLS/C1527132 denotes IL-6
T17703 184-188 UMLS/C1527132 denotes IL-6
T17702 158-162 UMLS/C1527132 denotes IL-6
T17701 0-4 UMLS/C1527132 denotes IL-6
T17700 2412-2418 UMLS/C1280500 denotes ect of
T17699 1749-1755 UMLS/C1280500 denotes effect
T17698 60-66 UMLS/C1280500 denotes effect
T17697 190-195 UMLS/C1334100 denotes IL-11
T17696 998-1001 UMLS/C0702093 denotes min
T17695 2029-2037 UMLS/C0242485 denotes asured b
T17694 1128-1132 UMLS/C0205548 denotes STAT
T17693 708-719 UMLS/C1273518 denotes responsible
T17692 2422-2427 UMLS/C1522550 denotes 10 in
T17691 2232-2237 UMLS/C1522550 denotes 10. T
T17690 2090-2095 UMLS/C1522550 denotes -10-m
T17689 1979-1984 UMLS/C1522550 denotes L-10
T17688 1759-1764 UMLS/C1522550 denotes IL-10
T17687 775-780 UMLS/C1522550 denotes IL-10
T17686 320-325 UMLS/C1522550 denotes IL-10
T17685 54-59 UMLS/C1522550 denotes IL-10
T17684 1811-1816 UMLS/C0687676 denotes fter
T17683 1900-1910 UMLS/C1948023 denotes timulated
T17682 2422-2427 UMLS/C1334098 denotes 10 in
T17681 2232-2237 UMLS/C1334098 denotes 10. T
T17680 2090-2095 UMLS/C1334098 denotes -10-m
T17679 1979-1984 UMLS/C1334098 denotes L-10
T17678 1759-1764 UMLS/C1334098 denotes IL-10
T17677 775-780 UMLS/C1334098 denotes IL-10
T17676 320-325 UMLS/C1334098 denotes IL-10
T17675 54-59 UMLS/C1334098 denotes IL-10
T17674 131-145 UP/P01136 denotes growth factors
T17673 2245-2253 UMLS/C1883357 denotes ether, t
T17672 344-351 UMLS/C2603343 denotes studies
T17671 1106-1113 UMLS/C0009932 denotes control
T17670 623-631 UMLS/C0728853 denotes exposure
T17669 173-182 UMLS/C1524094 denotes cytokines
T17668 117-126 UMLS/C1524094 denotes cytokines
T17667 344-351 UMLS/C2349977 denotes studies
T17666 2041-2046 UMLS/C0014441 denotes ISA.
T17665 2164-2168 UMLS/C1561957 denotes h co

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T18916 2438-2443 NN denotes cells
T18834 1956-1958 CC denotes or
T18833 1947-1955 NN denotes presence
T18832 1943-1946 DT denotes the
T18831 1940-1942 IN denotes in
T18830 1926-1939 NN denotes costimulation
T18829 1921-1925 NN denotes CD28
T18828 1917-1920 CC denotes and
T18827 1913-1916 NN denotes CD3
T18826 1910-1912 IN denotes by
T18825 1899-1909 VB denotes stimulated
T18824 1894-1898 VB denotes were
T18823 1888-1893 NN denotes cells
T18822 1886-1887 NN denotes T
T18821 1881-1885 JJ denotes CD4+
T18820 1874-1880 JJ denotes normal
T18819 1872-1873 -COMMA- denotes ,
T18818 1867-1872 NN denotes hours
T18817 1864-1866 CD denotes 36
T18816 1860-1863 IN denotes for
T18815 1855-1859 NN denotes IL-6
T18814 1849-1854 NN denotes ng/ml
T18813 1846-1848 CD denotes 10
T18812 1838-1845 IN denotes without
T18811 1835-1837 CC denotes or
T18810 1830-1834 IN denotes with
T18809 1816-1829 NN denotes preincubation
T18808 1810-1815 IN denotes After
T18807 1803-1808 NN denotes cells
T18806 1801-1802 NN denotes T
T18805 1796-1800 JJ denotes CD4+
T18804 1793-1795 IN denotes by
T18803 1782-1792 NN denotes production
T18802 1776-1781 NN denotes IFN-γ
T18801 1768-1775 VB denotes inhibit
T18800 1765-1767 TO denotes to
T18799 1759-1764 NN denotes IL-10
T18798 1756-1758 IN denotes of
T18797 1749-1755 NN denotes effect
T18796 1745-1748 DT denotes the
T18795 1736-1744 VB denotes suppress
T18794 1730-1735 MD denotes could
T18793 1725-1729 NN denotes IL-6
T18792 1717-1724 IN denotes whether
T18791 1708-1716 VB denotes examined
T18790 1703-1707 RB denotes next
T18789 1700-1702 PRP denotes We
T18788 1693-1698 NN denotes serum
T18787 1690-1692 NN denotes RA
T18786 1687-1689 IN denotes in
T18785 1679-1686 JJ denotes present
T18784 1676-1678 VB denotes be
T18783 1672-1675 MD denotes may
T18782 1662-1671 NN denotes signaling
T18781 1656-1661 NN denotes STAT1
T18780 1653-1655 IN denotes of
T18779 1642-1652 NN denotes inhibitors
T18778 1637-1641 IN denotes that
T18777 1634-1636 CC denotes or
T18776 1632-1633 -COMMA- denotes ,
T18775 1622-1632 NN denotes activation
T18774 1616-1621 NN denotes STAT3
T18773 1611-1615 IN denotes with
T18772 1602-1610 VB denotes compared
T18771 1599-1601 IN denotes as
T18770 1588-1598 NN denotes activation
T18769 1582-1587 NN denotes STAT1
T18768 1578-1581 IN denotes for
T18767 1569-1577 VB denotes required
T18766 1566-1568 VB denotes be
T18765 1562-1565 MD denotes may
T18764 1557-1561 NN denotes IL-6
T18763 1554-1556 IN denotes of
T18762 1539-1553 NN denotes concentrations
T18761 1532-1538 JJ denotes higher
T18760 1527-1531 RB denotes much
T18759 1522-1526 IN denotes that
T18758 1513-1521 VB denotes suggests
T18757 1507-1512 NN denotes serum
T18756 1504-1506 NN denotes RA
T18755 1501-1503 IN denotes by
T18754 1490-1500 NN denotes activation
T18753 1484-1489 NN denotes STAT1
T18752 1481-1483 IN denotes of
T18751 1476-1480 NN denotes lack
T18750 1472-1475 DT denotes The
T18749 1462-1470 NN denotes patients
T18748 1459-1461 NN denotes RA
T18747 1452-1458 JJ denotes active
T18746 1449-1451 IN denotes of
T18745 1444-1448 NN denotes sera
T18744 1441-1443 IN denotes in
T18743 1431-1440 VB denotes contained
T18742 1424-1430 NN denotes factor
T18741 1407-1423 JJ denotes STAT3-activating
T18740 1398-1406 JJ denotes dominant
T18739 1394-1397 DT denotes the
T18738 1391-1393 VB denotes is
T18737 1386-1390 NN denotes IL-6
T18736 1381-1385 IN denotes that
T18735 1372-1380 VB denotes indicate
T18734 1364-1371 NN denotes results
T18733 1358-1363 DT denotes These
T18732 1355-1356 -RRB- denotes )
T18731 1353-1355 NN denotes 5a
T18730 1348-1352 NN denotes Fig.
T18729 1347-1348 -LRB- denotes (
T18728 1338-1346 NN denotes activity
T18727 1333-1337 NN denotes IL-6
T18726 1330-1332 IN denotes of
T18725 1315-1329 NN denotes neutralization
T18724 1312-1314 IN denotes by
T18723 1302-1311 VB denotes abolished
T18722 1295-1301 RB denotes mostly
T18721 1291-1294 VB denotes was
T18720 1280-1290 NN denotes activation
T18719 1274-1279 NN denotes STAT3
T18718 1269-1273 DT denotes this
T18717 1265-1268 CC denotes and
T18716 1263-1264 -COMMA- denotes ,
T18715 1258-1263 NN denotes STAT1
T18714 1254-1257 RB denotes not
T18713 1250-1253 CC denotes but
T18712 1244-1249 NN denotes STAT3
T18711 1241-1243 IN denotes of
T18710 1225-1240 NN denotes phosphorylation
T18709 1216-1224 NN denotes tyrosine
T18708 1209-1215 VB denotes induce
T18707 1206-1208 TO denotes to
T18706 1201-1205 JJ denotes able
T18705 1197-1200 VB denotes was
T18704 1191-1196 NN denotes serum
T18703 1188-1190 NN denotes RA
T18702 1178-1186 NN denotes analysis
T18701 1173-1177 NN denotes blot
T18700 1165-1172 JJ denotes western
T18699 1162-1164 IN denotes by
T18698 1153-1161 VB denotes examined
T18697 1149-1152 VB denotes was
T18696 1133-1148 NN denotes phosphorylation
T18695 1128-1132 NN denotes STAT
T18694 1124-1127 CC denotes and
T18693 1122-1123 -COMMA- denotes ,
T18692 1114-1122 NN denotes antibody
T18691 1106-1113 NN denotes control
T18690 1103-1105 CC denotes or
T18689 1094-1102 NN denotes antibody
T18688 1084-1093 JJ denotes anti-IL-6
T18687 1071-1083 VB denotes neutralizing
T18686 1067-1070 CC denotes and
T18685 1058-1066 NN denotes patients
T18684 1055-1057 NN denotes RA
T18683 1048-1054 JJ denotes active
T18682 1043-1047 IN denotes from
T18681 1037-1042 NN denotes serum
T18680 1035-1036 NN denotes %
T18679 1033-1035 CD denotes 30
T18678 1022-1032 VB denotes containing
T18677 1015-1021 NN denotes medium
T18676 1007-1014 NN denotes culture
T18675 1002-1006 IN denotes with
T18674 998-1001 NN denotes min
T18673 995-997 CD denotes 20
T18672 991-994 IN denotes for
T18671 981-990 VB denotes incubated
T18670 976-980 RB denotes thus
T18669 971-975 VB denotes were
T18668 965-970 NN denotes cells
T18667 963-964 NN denotes T
T18666 958-962 JJ denotes CD4+
T18665 951-957 JJ denotes Normal
T18664 948-949 -RRB- denotes ]
T18663 947-948 CD denotes 4
T18662 946-947 -LRB- denotes [
T18661 933-945 NN denotes observations
T18660 924-932 JJ denotes previous
T18659 919-923 IN denotes with
T18658 909-918 NN denotes agreement
T18657 906-908 IN denotes in
T18656 904-905 -COMMA- denotes ,
T18655 903-904 -RRB- denotes )
T18654 898-903 VB denotes shown
T18653 894-897 RB denotes not
T18652 889-893 NN denotes data
T18651 888-889 -LRB- denotes (
T18650 882-887 NN denotes cells
T18649 880-881 NN denotes T
T18648 875-879 JJ denotes CD4+
T18647 868-874 JJ denotes normal
T18646 865-867 IN denotes in
T18645 860-864 NN denotes IL-6
T18644 857-859 IN denotes by
T18643 847-856 VB denotes activated
T18642 843-846 VB denotes was
T18641 827-842 NN denotes phosphorylation
T18640 821-826 NN denotes STAT3
T18639 817-820 CC denotes and
T18638 811-816 NN denotes STAT1
T18637 806-810 CC denotes Both
T18636 802-804 NN denotes RA
T18635 795-801 JJ denotes active
T18634 792-794 IN denotes in
T18633 781-791 NN denotes inhibition
T18632 775-780 NN denotes IL-10
T18631 772-774 TO denotes to
T18630 761-771 NN denotes resistance
T18629 757-760 CC denotes and
T18628 746-756 NN denotes activation
T18627 740-745 NN denotes STAT3
T18626 730-739 JJ denotes sustained
T18625 724-729 PRP-DOLLAR- denotes their
T18624 720-723 IN denotes for
T18623 708-719 JJ denotes responsible
T18622 704-707 VB denotes was
T18621 692-703 NN denotes circulation
T18620 686-691 NN denotes blood
T18619 682-685 DT denotes the
T18595 564-572 VB denotes detected
T18594 553-563 RB denotes frequently
T18593 551-552 -COMMA- denotes ,
T18592 543-551 NN denotes patients
T18591 540-542 NN denotes RA
T18590 533-539 JJ denotes active
T18589 530-532 IN denotes of
T18588 525-529 NN denotes sera
T18587 522-524 IN denotes in
T18586 513-521 JJ denotes abundant
T18585 508-512 RB denotes also
T18584 505-507 VB denotes is
T18583 500-504 NN denotes IL-6
T18582 494-499 IN denotes Since
T18581 491-492 -RRB- denotes ]
T18580 489-491 CD denotes 31
T18579 488-489 -LRB- denotes [
T18578 482-487 NN denotes cells
T18577 470-481 JJ denotes mononuclear
T18576 467-469 IN denotes in
T18575 461-466 NN denotes STAT3
T18574 458-460 IN denotes of
T18573 447-457 NN denotes activation
T18572 434-446 JJ denotes constitutive
T18571 426-433 VB denotes induces
T18570 421-425 WDT denotes that
T18569 415-420 NN denotes fluid
T18568 406-414 JJ denotes synovial
T18567 403-405 NN denotes RA
T18566 400-402 IN denotes in
T18565 393-399 NN denotes factor
T18564 387-392 JJ denotes major
T18563 383-386 DT denotes the
T18562 380-382 VB denotes is
T18561 375-379 NN denotes IL-6
T18560 370-374 IN denotes that
T18559 357-369 VB denotes demonstrated
T18558 352-356 VB denotes have
T18557 344-351 NN denotes studies
T18556 335-343 JJ denotes previous
T18555 331-334 CC denotes but
T18554 329-330 -COMMA- denotes ,
T18553 328-329 -RRB- denotes ]
T18552 327-328 CD denotes 4
T18551 326-327 -LRB- denotes [
T18550 320-325 NN denotes IL-10
T18549 317-319 TO denotes to
T18548 308-316 NN denotes addition
T18547 305-307 IN denotes in
T18546 303-304 -COMMA- denotes ,
T18545 297-303 NN denotes factor
T18544 290-296 NN denotes growth
T18543 280-289 JJ denotes epidermal
T18542 276-279 CC denotes and
T18541 274-275 -COMMA- denotes ,
T18540 268-274 NN denotes factor
T18539 261-267 NN denotes growth
T18538 244-260 JJ denotes platelet-derived
T18537 242-243 -COMMA- denotes ,
T18536 241-242 -RRB- denotes )
T18535 240-241 NN denotes M
T18534 229-239 NN denotes oncostatin
T18533 225-228 CC denotes and
T18532 223-224 -COMMA- denotes ,
T18531 217-223 NN denotes factor
T18530 206-216 JJ denotes inhibitory
T18529 197-205 NN denotes leukemia
T18528 195-196 -COMMA- denotes ,
T18527 190-195 NN denotes IL-11
T18526 188-189 -COMMA- denotes ,
T18525 184-188 NN denotes IL-6
T18524 183-184 -LRB- denotes (
T18523 173-182 NN denotes cytokines
T18522 170-172 IN denotes of
T18521 163-169 NN denotes family
T18520 158-162 NN denotes IL-6
T18519 154-157 DT denotes the
T18518 151-153 IN denotes as
T18517 146-150 JJ denotes such
T18516 138-145 NN denotes factors
T18515 131-137 NN denotes growth
T18514 127-130 CC denotes and
T18513 117-126 NN denotes cytokines
T18512 112-116 JJ denotes many
T18511 109-111 IN denotes by
T18510 99-108 VB denotes activated
T18509 96-98 VB denotes is
T18508 90-95 NN denotes STAT3
T18507 84-89 NN denotes cells
T18506 82-83 NN denotes T
T18505 77-81 JJ denotes CD4+
T18504 70-76 JJ denotes normal
T18503 67-69 IN denotes in
T18502 60-66 NN denotes effect
T18501 54-59 NN denotes IL-10
T18500 51-53 IN denotes of
T18499 40-50 NN denotes inhibition
T18498 36-39 CC denotes and
T18497 20-35 NN denotes phosphorylation
T18496 14-19 NN denotes STAT3
T18495 0-13 JJ denotes IL-6-mediated
T18915 2436-2437 NN denotes T
T18914 2431-2435 JJ denotes CD4+
T18913 2428-2430 NN denotes RA
T18912 2425-2427 IN denotes in
T18911 2419-2424 NN denotes IL-10
T18910 2416-2418 IN denotes of
T18909 2409-2415 NN denotes effect
T18908 2398-2408 JJ denotes inhibitory
T18907 2394-2397 DT denotes the
T18906 2391-2393 TO denotes to
T18905 2380-2390 NN denotes resistance
T18904 2376-2379 DT denotes the
T18903 2372-2375 CC denotes and
T18902 2361-2371 NN denotes activation
T18901 2355-2360 NN denotes STAT3
T18900 2352-2354 IN denotes of
T18899 2342-2351 NN denotes induction
T18898 2338-2341 DT denotes the
T18897 2333-2337 CC denotes both
T18896 2330-2332 IN denotes in
T18895 2325-2329 NN denotes role
T18894 2323-2324 DT denotes a
T18893 2318-2322 VB denotes have
T18892 2314-2317 MD denotes may
T18891 2309-2313 NN denotes IL-6
T18890 2303-2308 NN denotes serum
T18889 2300-2302 TO denotes to
T18888 2291-2299 NN denotes exposure
T18887 2280-2290 JJ denotes persistent
T18886 2275-2279 IN denotes that
T18885 2267-2274 VB denotes suggest
T18884 2258-2266 NN denotes findings
T18883 2252-2257 DT denotes these
T18882 2250-2251 -COMMA- denotes ,
T18881 2242-2250 RB denotes together
T18880 2236-2241 VB denotes Taken
T18879 2229-2234 NN denotes IL-10
T18878 2226-2228 TO denotes to
T18877 2211-2225 NN denotes responsiveness
T18876 2204-2210 NN denotes T-cell
T18875 2195-2203 VB denotes modulate
T18874 2189-2194 MD denotes could
T18873 2184-2188 NN denotes IL-6
T18872 2181-2183 IN denotes of
T18871 2166-2180 NN denotes concentrations
T18870 2161-2165 JJ denotes high
T18869 2156-2160 IN denotes that
T18868 2145-2155 VB denotes indicating
T18867 2143-2144 -COMMA- denotes ,
T18866 2142-2143 -RRB- denotes )
T18865 2140-2142 NN denotes 5b
T18864 2135-2139 NN denotes Fig.
T18863 2134-2135 -LRB- denotes (
T18862 2123-2133 NN denotes production
T18861 2117-2122 NN denotes IFN-γ
T18860 2114-2116 IN denotes of
T18859 2103-2113 NN denotes inhibition
T18858 2088-2102 JJ denotes IL-10-mediated
T18857 2080-2087 VB denotes reduced
T18856 2074-2079 NN denotes cells
T18855 2067-2073 JJ denotes normal
T18854 2064-2066 IN denotes of
T18853 2051-2063 NN denotes pretreatment
T18852 2046-2050 NN denotes IL-6
T18851 2039-2044 NN denotes ELISA
T18850 2036-2038 IN denotes by
T18849 2027-2035 VB denotes measured
T18848 2023-2026 VB denotes was
T18847 2012-2022 NN denotes production
T18846 2006-2011 NN denotes IFN-γ
T18845 2002-2005 DT denotes the
T18844 1998-2001 CC denotes and
T18843 1996-1997 -COMMA- denotes ,
T18842 1991-1996 NN denotes hours
T18841 1988-1990 CD denotes 36
T18840 1984-1987 IN denotes for
T18839 1978-1983 NN denotes IL-10
T18838 1972-1977 NN denotes ng/ml
T18837 1970-1971 CD denotes 1
T18836 1967-1969 IN denotes of
T18835 1959-1966 NN denotes absence
T18618 679-681 IN denotes in
T18617 674-678 NN denotes IL-6
T18616 671-673 IN denotes of
T18615 656-670 NN denotes concentrations
T18614 651-655 JJ denotes high
T18613 648-650 TO denotes to
T18612 642-647 NN denotes cells
T18611 640-641 NN denotes T
T18610 635-639 JJ denotes CD4+
T18609 632-634 IN denotes of
T18608 623-631 NN denotes exposure
T18607 612-622 JJ denotes persistent
T18606 604-611 IN denotes whether
T18605 595-603 VB denotes examined
T18604 592-594 PRP denotes we
T18603 590-591 -COMMA- denotes ,
T18602 589-590 -RRB- denotes ]
T18601 587-589 CD denotes 27
T18600 586-587 -LRB- denotes [
T18599 580-585 NN denotes ng/ml
T18598 578-579 CD denotes 1
T18597 576-577 SYM denotes >
T18596 573-575 IN denotes at
R8964 T18497 T18495 arg1Of phosphorylation,IL-6-mediated
R8965 T18497 T18496 arg1Of phosphorylation,STAT3
R8966 T18497 T18498 arg1Of phosphorylation,and
R8967 T18498 T18503 arg1Of and,in
R8968 T18499 T18498 arg2Of inhibition,and
R8969 T18499 T18500 arg1Of inhibition,of
R8970 T18502 T18500 arg2Of effect,of
R8971 T18502 T18501 arg1Of effect,IL-10
R8972 T18507 T18503 arg2Of cells,in
R8973 T18507 T18504 arg1Of cells,normal
R8974 T18507 T18505 arg1Of cells,CD4+
R8975 T18507 T18506 arg1Of cells,T
R8976 T18508 T18509 arg1Of STAT3,is
R8977 T18508 T18510 arg2Of STAT3,activated
R8978 T18510 T18509 arg2Of activated,is
R8979 T18510 T18546 arg1Of activated,","
R8980 T18510 T18547 arg1Of activated,in
R8981 T18510 T18555 arg1Of activated,but
R8982 T18513 T18512 arg1Of cytokines,many
R8983 T18513 T18514 arg1Of cytokines,and
R8984 T18514 T18510 arg1Of and,activated
R8985 T18514 T18511 arg2Of and,by
R8986 T18514 T18518 arg1Of and,as
R8987 T18516 T18514 arg2Of factors,and
R8988 T18516 T18515 arg1Of factors,growth
R8989 T18518 T18517 arg1Of as,such
R8990 T18521 T18520 arg1Of family,IL-6
R8991 T18521 T18522 arg1Of family,of
R8992 T18521 T18542 arg1Of family,and
R8993 T18523 T18524 arg1Of cytokines,(
R8994 T18523 T18537 arg1Of cytokines,","
R8995 T18525 T18526 arg1Of IL-6,","
R8996 T18526 T18528 arg1Of ",",","
R8997 T18527 T18526 arg2Of IL-11,","
R8998 T18528 T18533 arg1Of ",",and
R8999 T18531 T18528 arg2Of factor,","
R9000 T18531 T18529 arg1Of factor,leukemia
R9001 T18531 T18530 arg1Of factor,inhibitory
R9002 T18533 T18524 arg2Of and,(
R9003 T18533 T18532 arg1Of and,","
R9004 T18535 T18533 arg2Of M,and
R9005 T18535 T18534 arg1Of M,oncostatin
R9006 T18536 T18524 arg3Of ),(
R9007 T18537 T18522 arg2Of ",",of
R9008 T18540 T18537 arg2Of factor,","
R9009 T18540 T18538 arg1Of factor,platelet-derived
R9010 T18540 T18539 arg1Of factor,growth
R9011 T18542 T18518 arg2Of and,as
R9012 T18542 T18519 arg1Of and,the
R9013 T18542 T18541 arg1Of and,","
R9014 T18545 T18542 arg2Of factor,and
R9015 T18545 T18543 arg1Of factor,epidermal
R9016 T18545 T18544 arg1Of factor,growth
R9017 T18548 T18547 arg2Of addition,in
R9018 T18548 T18549 arg1Of addition,to
R9019 T18550 T18549 arg2Of IL-10,to
R9020 T18550 T18551 arg1Of IL-10,[
R9021 T18552 T18551 arg2Of 4,[
R9022 T18553 T18551 arg3Of ],[
R9023 T18555 T18554 arg1Of but,","
R9024 T18557 T18556 arg1Of studies,previous
R9025 T18557 T18558 arg1Of studies,have
R9026 T18557 T18559 arg1Of studies,demonstrated
R9027 T18559 T18555 arg2Of demonstrated,but
R9028 T18559 T18558 arg2Of demonstrated,have
R9029 T18561 T18562 arg1Of IL-6,is
R9030 T18562 T18559 arg2Of is,demonstrated
R9031 T18562 T18560 arg1Of is,that
R9032 T18565 T18562 arg2Of factor,is
R9033 T18565 T18563 arg1Of factor,the
R9034 T18565 T18564 arg1Of factor,major
R9035 T18565 T18566 arg1Of factor,in
R9036 T18565 T18570 arg1Of factor,that
R9037 T18565 T18571 arg1Of factor,induces
R9038 T18569 T18566 arg2Of fluid,in
R9039 T18569 T18567 arg1Of fluid,RA
R9040 T18569 T18568 arg1Of fluid,synovial
R9041 T18571 T18579 arg1Of induces,[
R9042 T18573 T18571 arg2Of activation,induces
R9043 T18573 T18572 arg1Of activation,constitutive
R9044 T18573 T18574 arg1Of activation,of
R9045 T18573 T18576 arg1Of activation,in
R9046 T18575 T18574 arg2Of STAT3,of
R9047 T18578 T18576 arg2Of cells,in
R9048 T18578 T18577 arg1Of cells,mononuclear
R9049 T18580 T18579 arg2Of 31,[
R9050 T18581 T18579 arg3Of ],[
R9051 T18583 T18584 arg1Of IL-6,is
R9052 T18583 T18586 arg1Of IL-6,abundant
R9053 T18584 T18582 arg2Of is,Since
R9054 T18584 T18585 arg1Of is,also
R9055 T18584 T18587 arg1Of is,in
R9056 T18586 T18584 arg2Of abundant,is
R9057 T18588 T18587 arg2Of sera,in
R9058 T18588 T18589 arg1Of sera,of
R9059 T18592 T18589 arg2Of patients,of
R9060 T18592 T18590 arg1Of patients,active
R9061 T18592 T18591 arg1Of patients,RA
R9062 T18592 T18593 arg1Of patients,","
R9063 T18592 T18595 arg2Of patients,detected
R9064 T18595 T18594 arg1Of detected,frequently
R9065 T18595 T18596 arg1Of detected,at
R9066 T18598 T18597 arg1Of 1,>
R9067 T18599 T18596 arg2Of ng/ml,at
R9068 T18599 T18598 arg1Of ng/ml,1
R9069 T18599 T18600 arg1Of ng/ml,[
R9070 T18601 T18600 arg2Of 27,[
R9071 T18602 T18600 arg3Of ],[
R9072 T18604 T18605 arg1Of we,examined
R9073 T18605 T18582 arg1Of examined,Since
R9074 T18605 T18603 arg1Of examined,","
R9075 T18608 T18607 arg1Of exposure,persistent
R9076 T18608 T18609 arg1Of exposure,of
R9077 T18608 T18613 arg1Of exposure,to
R9078 T18608 T18618 arg1Of exposure,in
R9079 T18608 T18622 arg1Of exposure,was
R9080 T18608 T18623 arg1Of exposure,responsible
R9081 T18612 T18609 arg2Of cells,of
R9082 T18612 T18610 arg1Of cells,CD4+
R9083 T18612 T18611 arg1Of cells,T
R9084 T18615 T18613 arg2Of concentrations,to
R9085 T18615 T18614 arg1Of concentrations,high
R9086 T18615 T18616 arg1Of concentrations,of
R9087 T18617 T18616 arg2Of IL-6,of
R9088 T18621 T18618 arg2Of circulation,in
R9089 T18621 T18619 arg1Of circulation,the
R9090 T18621 T18620 arg1Of circulation,blood
R9091 T18622 T18605 arg2Of was,examined
R9092 T18622 T18606 arg1Of was,whether
R9093 T18623 T18622 arg2Of responsible,was
R9094 T18623 T18624 arg1Of responsible,for
R9095 T18628 T18626 arg1Of activation,sustained
R9096 T18628 T18627 arg1Of activation,STAT3
R9097 T18628 T18629 arg1Of activation,and
R9098 T18629 T18624 arg2Of and,for
R9099 T18629 T18625 arg1Of and,their
R9100 T18629 T18634 arg1Of and,in
R9101 T18630 T18629 arg2Of resistance,and
R9102 T18630 T18631 arg1Of resistance,to
R9103 T18633 T18631 arg2Of inhibition,to
R9104 T18633 T18632 arg1Of inhibition,IL-10
R9105 T18636 T18634 arg2Of RA,in
R9106 T18636 T18635 arg1Of RA,active
R9107 T18638 T18639 arg1Of STAT1,and
R9108 T18640 T18639 arg2Of STAT3,and
R9109 T18641 T18637 arg1Of phosphorylation,Both
R9110 T18641 T18638 arg1Of phosphorylation,STAT1
R9111 T18641 T18640 arg1Of phosphorylation,STAT3
R9112 T18641 T18642 arg1Of phosphorylation,was
R9113 T18641 T18643 arg2Of phosphorylation,activated
R9114 T18643 T18642 arg2Of activated,was
R9115 T18643 T18646 arg1Of activated,in
R9116 T18643 T18656 arg1Of activated,","
R9117 T18643 T18657 arg1Of activated,in
R9118 T18645 T18643 arg1Of IL-6,activated
R9119 T18645 T18644 arg2Of IL-6,by
R9120 T18650 T18646 arg2Of cells,in
R9121 T18650 T18647 arg1Of cells,normal
R9122 T18650 T18648 arg1Of cells,CD4+
R9123 T18650 T18649 arg1Of cells,T
R9124 T18650 T18651 arg1Of cells,(
R9125 T18652 T18651 arg2Of data,(
R9126 T18652 T18654 arg2Of data,shown
R9127 T18654 T18653 arg1Of shown,not
R9128 T18655 T18651 arg3Of ),(
R9129 T18658 T18657 arg2Of agreement,in
R9130 T18658 T18659 arg1Of agreement,with
R9131 T18661 T18659 arg2Of observations,with
R9132 T18661 T18660 arg1Of observations,previous
R9133 T18661 T18662 arg1Of observations,[
R9134 T18663 T18662 arg2Of 4,[
R9135 T18664 T18662 arg3Of ],[
R9136 T18668 T18665 arg1Of cells,Normal
R9137 T18668 T18666 arg1Of cells,CD4+
R9138 T18668 T18667 arg1Of cells,T
R9139 T18668 T18669 arg1Of cells,were
R9140 T18668 T18671 arg2Of cells,incubated
R9141 T18668 T18687 arg1Of cells,neutralizing
R9142 T18671 T18670 arg1Of incubated,thus
R9143 T18671 T18672 arg1Of incubated,for
R9144 T18671 T18675 arg1Of incubated,with
R9145 T18671 T18686 arg1Of incubated,and
R9146 T18674 T18672 arg2Of min,for
R9147 T18674 T18673 arg1Of min,20
R9148 T18677 T18675 arg2Of medium,with
R9149 T18677 T18676 arg1Of medium,culture
R9150 T18677 T18678 arg1Of medium,containing
R9151 T18679 T18680 arg1Of 30,%
R9152 T18681 T18678 arg2Of serum,containing
R9153 T18681 T18679 arg1Of serum,30
R9154 T18681 T18682 arg1Of serum,from
R9155 T18685 T18682 arg2Of patients,from
R9156 T18685 T18683 arg1Of patients,active
R9157 T18685 T18684 arg1Of patients,RA
R9158 T18686 T18669 arg2Of and,were
R9159 T18686 T18694 arg1Of and,and
R9160 T18687 T18686 arg2Of neutralizing,and
R9161 T18689 T18690 arg1Of antibody,or
R9162 T18691 T18690 arg2Of control,or
R9163 T18692 T18687 arg2Of antibody,neutralizing
R9164 T18692 T18688 arg1Of antibody,anti-IL-6
R9165 T18692 T18689 arg1Of antibody,antibody
R9166 T18692 T18691 arg1Of antibody,control
R9167 T18694 T18693 arg1Of and,","
R9168 T18696 T18695 arg1Of phosphorylation,STAT
R9169 T18696 T18697 arg1Of phosphorylation,was
R9170 T18696 T18698 arg2Of phosphorylation,examined
R9171 T18698 T18694 arg2Of examined,and
R9172 T18698 T18697 arg2Of examined,was
R9173 T18702 T18698 arg1Of analysis,examined
R9174 T18702 T18699 arg2Of analysis,by
R9175 T18702 T18700 arg1Of analysis,western
R9176 T18702 T18701 arg1Of analysis,blot
R9177 T18704 T18703 arg1Of serum,RA
R9178 T18704 T18705 arg1Of serum,was
R9179 T18704 T18706 arg1Of serum,able
R9180 T18704 T18708 arg1Of serum,induce
R9181 T18705 T18717 arg1Of was,and
R9182 T18706 T18705 arg2Of able,was
R9183 T18708 T18706 arg2Of induce,able
R9184 T18708 T18707 arg1Of induce,to
R9185 T18710 T18708 arg2Of phosphorylation,induce
R9186 T18710 T18709 arg1Of phosphorylation,tyrosine
R9187 T18710 T18711 arg1Of phosphorylation,of
R9188 T18712 T18713 arg1Of STAT3,but
R9189 T18713 T18711 arg2Of but,of
R9190 T18713 T18714 arg1Of but,not
R9191 T18715 T18713 arg2Of STAT1,but
R9192 T18717 T18716 arg1Of and,","
R9193 T18720 T18718 arg1Of activation,this
R9194 T18720 T18719 arg1Of activation,STAT3
R9195 T18720 T18721 arg1Of activation,was
R9196 T18720 T18723 arg2Of activation,abolished
R9197 T18723 T18717 arg2Of abolished,and
R9198 T18723 T18721 arg2Of abolished,was
R9199 T18723 T18722 arg1Of abolished,mostly
R9200 T18725 T18723 arg1Of neutralization,abolished
R9201 T18725 T18724 arg2Of neutralization,by
R9202 T18725 T18726 arg1Of neutralization,of
R9203 T18728 T18726 arg2Of activity,of
R9204 T18728 T18727 arg1Of activity,IL-6
R9205 T18728 T18729 arg1Of activity,(
R9206 T18731 T18729 arg2Of 5a,(
R9207 T18731 T18730 arg1Of 5a,Fig.
R9208 T18732 T18729 arg3Of ),(
R9209 T18734 T18733 arg1Of results,These
R9210 T18734 T18735 arg1Of results,indicate
R9211 T18737 T18738 arg1Of IL-6,is
R9212 T18738 T18735 arg2Of is,indicate
R9213 T18738 T18736 arg1Of is,that
R9214 T18742 T18738 arg2Of factor,is
R9215 T18742 T18739 arg1Of factor,the
R9216 T18742 T18740 arg1Of factor,dominant
R9217 T18742 T18741 arg1Of factor,STAT3-activating
R9218 T18742 T18743 arg2Of factor,contained
R9219 T18743 T18744 arg1Of contained,in
R9220 T18745 T18744 arg2Of sera,in
R9221 T18745 T18746 arg1Of sera,of
R9222 T18749 T18746 arg2Of patients,of
R9223 T18749 T18747 arg1Of patients,active
R9224 T18749 T18748 arg1Of patients,RA
R9225 T18751 T18750 arg1Of lack,The
R9226 T18751 T18752 arg1Of lack,of
R9227 T18751 T18755 arg1Of lack,by
R9228 T18751 T18758 arg1Of lack,suggests
R9229 T18754 T18752 arg2Of activation,of
R9230 T18754 T18753 arg1Of activation,STAT1
R9231 T18757 T18755 arg2Of serum,by
R9232 T18757 T18756 arg1Of serum,RA
R9233 T18761 T18760 arg1Of higher,much
R9234 T18762 T18761 arg1Of concentrations,higher
R9235 T18762 T18763 arg1Of concentrations,of
R9236 T18762 T18765 arg1Of concentrations,may
R9237 T18762 T18766 arg1Of concentrations,be
R9238 T18762 T18767 arg2Of concentrations,required
R9239 T18764 T18763 arg2Of IL-6,of
R9240 T18767 T18759 arg1Of required,that
R9241 T18767 T18765 arg2Of required,may
R9242 T18767 T18766 arg2Of required,be
R9243 T18767 T18768 arg1Of required,for
R9244 T18767 T18771 arg1Of required,as
R9245 T18767 T18777 arg1Of required,or
R9246 T18770 T18768 arg2Of activation,for
R9247 T18770 T18769 arg1Of activation,STAT1
R9248 T18772 T18771 arg2Of compared,as
R9249 T18772 T18773 arg1Of compared,with
R9250 T18775 T18773 arg2Of activation,with
R9251 T18775 T18774 arg1Of activation,STAT3
R9252 T18777 T18758 arg2Of or,suggests
R9253 T18777 T18776 arg1Of or,","
R9254 T18778 T18777 arg2Of that,or
R9255 T18779 T18780 arg1Of inhibitors,of
R9256 T18779 T18783 arg1Of inhibitors,may
R9257 T18779 T18784 arg1Of inhibitors,be
R9258 T18779 T18785 arg1Of inhibitors,present
R9259 T18782 T18780 arg2Of signaling,of
R9260 T18782 T18781 arg1Of signaling,STAT1
R9261 T18784 T18778 arg2Of be,that
R9262 T18784 T18783 arg2Of be,may
R9263 T18785 T18784 arg2Of present,be
R9264 T18785 T18786 arg1Of present,in
R9265 T18788 T18786 arg2Of serum,in
R9266 T18788 T18787 arg1Of serum,RA
R9267 T18789 T18791 arg1Of We,examined
R9268 T18791 T18790 arg1Of examined,next
R9269 T18793 T18794 arg1Of IL-6,could
R9270 T18793 T18795 arg1Of IL-6,suppress
R9271 T18795 T18791 arg2Of suppress,examined
R9272 T18795 T18792 arg1Of suppress,whether
R9273 T18795 T18794 arg2Of suppress,could
R9274 T18797 T18795 arg2Of effect,suppress
R9275 T18797 T18796 arg1Of effect,the
R9276 T18797 T18798 arg1Of effect,of
R9277 T18797 T18800 modOf effect,to
R9278 T18799 T18798 arg2Of IL-10,of
R9279 T18801 T18800 arg1Of inhibit,to
R9280 T18801 T18804 arg1Of inhibit,by
R9281 T18803 T18801 arg2Of production,inhibit
R9282 T18803 T18802 arg1Of production,IFN-γ
R9283 T18807 T18804 arg2Of cells,by
R9284 T18807 T18805 arg1Of cells,CD4+
R9285 T18807 T18806 arg1Of cells,T
R9286 T18809 T18808 arg2Of preincubation,After
R9287 T18809 T18810 arg1Of preincubation,with
R9288 T18809 T18812 arg1Of preincubation,without
R9289 T18809 T18816 arg1Of preincubation,for
R9290 T18810 T18811 arg1Of with,or
R9291 T18812 T18811 arg2Of without,or
R9292 T18813 T18814 arg1Of 10,ng/ml
R9293 T18815 T18810 arg2Of IL-6,with
R9294 T18815 T18812 arg2Of IL-6,without
R9295 T18815 T18813 arg1Of IL-6,10
R9296 T18818 T18816 arg2Of hours,for
R9297 T18818 T18817 arg1Of hours,36
R9298 T18823 T18820 arg1Of cells,normal
R9299 T18823 T18821 arg1Of cells,CD4+
R9300 T18823 T18822 arg1Of cells,T
R9301 T18823 T18824 arg1Of cells,were
R9302 T18823 T18825 arg2Of cells,stimulated
R9303 T18825 T18824 arg2Of stimulated,were
R9304 T18825 T18844 arg1Of stimulated,and
R9305 T18827 T18828 arg1Of CD3,and
R9306 T18828 T18825 arg1Of and,stimulated
R9307 T18828 T18826 arg2Of and,by
R9308 T18828 T18831 arg1Of and,in
R9309 T18830 T18828 arg2Of costimulation,and
R9310 T18830 T18829 arg1Of costimulation,CD28
R9311 T18833 T18834 arg1Of presence,or
R9312 T18834 T18831 arg2Of or,in
R9313 T18834 T18832 arg1Of or,the
R9314 T18834 T18836 arg1Of or,of
R9315 T18835 T18834 arg2Of absence,or
R9316 T18837 T18838 arg1Of 1,ng/ml
R9317 T18839 T18836 arg2Of IL-10,of
R9318 T18839 T18837 arg1Of IL-10,1
R9319 T18839 T18840 arg1Of IL-10,for
R9320 T18842 T18840 arg2Of hours,for
R9321 T18842 T18841 arg1Of hours,36
R9322 T18844 T18808 arg1Of and,After
R9323 T18844 T18819 arg1Of and,","
R9324 T18844 T18843 arg1Of and,","
R9325 T18847 T18845 arg1Of production,the
R9326 T18847 T18846 arg1Of production,IFN-γ
R9327 T18847 T18848 arg1Of production,was
R9328 T18847 T18849 arg2Of production,measured
R9329 T18849 T18844 arg2Of measured,and
R9330 T18849 T18848 arg2Of measured,was
R9331 T18851 T18849 arg1Of ELISA,measured
R9332 T18851 T18850 arg2Of ELISA,by
R9333 T18853 T18852 arg1Of pretreatment,IL-6
R9334 T18853 T18854 arg1Of pretreatment,of
R9335 T18853 T18857 arg1Of pretreatment,reduced
R9336 T18856 T18854 arg2Of cells,of
R9337 T18856 T18855 arg1Of cells,normal
R9338 T18857 T18867 arg1Of reduced,","
R9339 T18857 T18868 modOf reduced,indicating
R9340 T18859 T18857 arg2Of inhibition,reduced
R9341 T18859 T18858 arg1Of inhibition,IL-10-mediated
R9342 T18859 T18860 arg1Of inhibition,of
R9343 T18862 T18860 arg2Of production,of
R9344 T18862 T18861 arg1Of production,IFN-γ
R9345 T18862 T18863 arg1Of production,(
R9346 T18865 T18863 arg2Of 5b,(
R9347 T18865 T18864 arg1Of 5b,Fig.
R9348 T18866 T18863 arg3Of ),(
R9349 T18871 T18870 arg1Of concentrations,high
R9350 T18871 T18872 arg1Of concentrations,of
R9351 T18871 T18874 arg1Of concentrations,could
R9352 T18871 T18875 arg1Of concentrations,modulate
R9353 T18873 T18872 arg2Of IL-6,of
R9354 T18875 T18868 arg2Of modulate,indicating
R9355 T18875 T18869 arg1Of modulate,that
R9356 T18875 T18874 arg2Of modulate,could
R9357 T18877 T18875 arg2Of responsiveness,modulate
R9358 T18877 T18876 arg1Of responsiveness,T-cell
R9359 T18877 T18878 arg1Of responsiveness,to
R9360 T18879 T18878 arg2Of IL-10,to
R9361 T18880 T18881 arg1Of Taken,together
R9362 T18884 T18883 arg1Of findings,these
R9363 T18884 T18885 arg1Of findings,suggest
R9364 T18885 T18880 modOf suggest,Taken
R9365 T18885 T18882 arg1Of suggest,","
R9366 T18888 T18887 arg1Of exposure,persistent
R9367 T18888 T18889 arg1Of exposure,to
R9368 T18888 T18892 arg1Of exposure,may
R9369 T18888 T18893 arg1Of exposure,have
R9370 T18891 T18889 arg2Of IL-6,to
R9371 T18891 T18890 arg1Of IL-6,serum
R9372 T18893 T18885 arg2Of have,suggest
R9373 T18893 T18886 arg1Of have,that
R9374 T18893 T18892 arg2Of have,may
R9375 T18893 T18896 arg1Of have,in
R9376 T18895 T18893 arg2Of role,have
R9377 T18895 T18894 arg1Of role,a
R9378 T18899 T18898 arg1Of induction,the
R9379 T18899 T18900 arg1Of induction,of
R9380 T18899 T18903 arg1Of induction,and
R9381 T18902 T18900 arg2Of activation,of
R9382 T18902 T18901 arg1Of activation,STAT3
R9383 T18903 T18896 arg2Of and,in
R9384 T18903 T18897 arg1Of and,both
R9385 T18905 T18903 arg2Of resistance,and
R9386 T18905 T18904 arg1Of resistance,the
R9387 T18905 T18906 arg1Of resistance,to
R9388 T18909 T18906 arg2Of effect,to
R9389 T18909 T18907 arg1Of effect,the
R9390 T18909 T18908 arg1Of effect,inhibitory
R9391 T18909 T18910 arg1Of effect,of
R9392 T18909 T18912 arg1Of effect,in
R9393 T18911 T18910 arg2Of IL-10,of
R9394 T18916 T18912 arg2Of cells,in
R9395 T18916 T18913 arg1Of cells,RA
R9396 T18916 T18914 arg1Of cells,CD4+
R9397 T18916 T18915 arg1Of cells,T

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T18143 375-379 Antecedent denotes IL-6
T18142 383-399 Anaphor denotes the major factor
T18141 229-241 Antecedent denotes oncostatin M
T18140 197-223 Antecedent denotes leukemia inhibitory factor
T18139 190-195 Antecedent denotes IL-11
T18138 184-188 Antecedent denotes IL-6
T18137 158-182 Anaphor denotes IL-6 family of cytokines
T18136 280-303 Antecedent denotes epidermal growth factor
T18135 244-274 Antecedent denotes platelet-derived growth factor
T18134 112-145 Anaphor denotes many cytokines and growth factors
T18147 1386-1390 Antecedent denotes IL-6
T18146 1424-1430 Anaphor denotes factor
T18145 383-399 Antecedent denotes the major factor
T18144 421-425 Anaphor denotes that
R8893 T18134 T18135 boundBy many cytokines and growth factors,platelet-derived growth factor
R8894 T18134 T18136 boundBy many cytokines and growth factors,epidermal growth factor
R8895 T18137 T18138 boundBy IL-6 family of cytokines,IL-6
R8896 T18137 T18139 boundBy IL-6 family of cytokines,IL-11
R8897 T18137 T18140 boundBy IL-6 family of cytokines,leukemia inhibitory factor
R8898 T18137 T18141 boundBy IL-6 family of cytokines,oncostatin M
R8899 T18142 T18143 boundBy the major factor,IL-6
R8900 T18144 T18142 boundBy that,the major factor
R8901 T18146 T18147 boundBy factor,IL-6

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T18162 500-504 Protein denotes IL-6
T18161 461-466 Protein denotes STAT3
T18160 375-379 Protein denotes IL-6
T18159 320-325 Protein denotes IL-10
T18158 280-303 Protein denotes epidermal growth factor
T18157 244-274 Protein denotes platelet-derived growth factor
T18156 229-241 Protein denotes oncostatin M
T18155 197-223 Protein denotes leukemia inhibitory factor
T18154 190-195 Protein denotes IL-11
T18153 184-188 Protein denotes IL-6
T18152 90-95 Protein denotes STAT3
T18151 77-80 Protein denotes CD4
T18150 54-59 Protein denotes IL-10
T18149 14-19 Protein denotes STAT3
T18148 0-4 Protein denotes IL-6
T18201 2431-2434 Protein denotes CD4
T18200 2419-2424 Protein denotes IL-10
T18199 2355-2360 Protein denotes STAT3
T18198 2309-2313 Protein denotes IL-6
T18197 2229-2234 Protein denotes IL-10
T18196 2184-2188 Protein denotes IL-6
T18195 2117-2122 Protein denotes IFN-γ
T18194 2088-2093 Protein denotes IL-10
T18193 2046-2050 Protein denotes IL-6
T18192 2006-2011 Protein denotes IFN-γ
T18191 1978-1983 Protein denotes IL-10
T18190 1921-1925 Protein denotes CD28
T18189 1881-1884 Protein denotes CD4
T18188 1855-1859 Protein denotes IL-6
T18187 1796-1799 Protein denotes CD4
T18186 1776-1781 Protein denotes IFN-γ
T18185 1759-1764 Protein denotes IL-10
T18184 1725-1729 Protein denotes IL-6
T18183 1656-1661 Protein denotes STAT1
T18182 1616-1621 Protein denotes STAT3
T18181 1582-1587 Protein denotes STAT1
T18180 1557-1561 Protein denotes IL-6
T18179 1484-1489 Protein denotes STAT1
T18178 1407-1412 Protein denotes STAT3
T18177 1386-1390 Protein denotes IL-6
T18176 1333-1337 Protein denotes IL-6
T18175 1274-1279 Protein denotes STAT3
T18174 1258-1263 Protein denotes STAT1
T18173 1244-1249 Protein denotes STAT3
T18172 1089-1093 Protein denotes IL-6
T18171 958-961 Protein denotes CD4
T18170 875-878 Protein denotes CD4
T18169 860-864 Protein denotes IL-6
T18168 821-826 Protein denotes STAT3
T18167 811-816 Protein denotes STAT1
T18166 775-780 Protein denotes IL-10
T18165 740-745 Protein denotes STAT3
T18164 674-678 Protein denotes IL-6
T18163 635-638 Protein denotes CD4

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T18440 1921-1925 http://www.uniprot.org/uniprot/P10747 denotes CD28
T18439 1913-1916 http://www.uniprot.org/uniprot/P09693 denotes CD3
T18438 1913-1916 http://www.uniprot.org/uniprot/P07766 denotes CD3
T18437 1913-1916 http://www.uniprot.org/uniprot/P04234 denotes CD3
T18436 1913-1916 http://www.uniprot.org/uniprot/P20963 denotes CD3
T18435 2117-2122 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T18434 2006-2011 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T18433 1776-1781 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T18432 2431-2434 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18431 1881-1884 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18430 1796-1799 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18429 958-961 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18428 875-878 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18427 635-638 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18426 77-80 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18425 2419-2424 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18424 2229-2234 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18423 2088-2093 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18422 1978-1983 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18421 1759-1764 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18420 775-780 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18419 320-325 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18418 54-59 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18417 2355-2360 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18416 1616-1621 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18415 1407-1412 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18414 1274-1279 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18413 1244-1249 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18412 821-826 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18411 740-745 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18410 461-466 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18409 90-95 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18408 14-19 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18407 2309-2313 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18406 2184-2188 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18405 2046-2050 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18404 1855-1859 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18403 1725-1729 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18402 1557-1561 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18401 1386-1390 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18400 1333-1337 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18399 1089-1093 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18398 860-864 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18397 674-678 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18396 500-504 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18395 375-379 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18394 184-188 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18393 158-162 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18392 0-4 http://www.uniprot.org/uniprot/P05231 denotes IL-6

UBERON-AE

Id Subject Object Predicate Lexical cue
T17463 2303-2308 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17462 1693-1698 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17461 1507-1512 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17460 1191-1196 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17459 1037-1042 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17458 686-691 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T17457 406-420 http://purl.obolibrary.org/obo/UBERON_0001090 denotes synovial fluid

GO-BP

Id Subject Object Predicate Lexical cue
T18034 2103-2122 http://purl.obolibrary.org/obo/GO_1902714 denotes inhibition of IFN-γ
T18033 1662-1671 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T18032 1333-1346 http://purl.obolibrary.org/obo/GO_0004915 denotes IL-6 activity
T18031 827-856 http://purl.obolibrary.org/obo/GO_0042327 denotes phosphorylation was activated
T18030 686-703 http://purl.obolibrary.org/obo/GO_0008015 denotes blood circulation
T18029 261-289 http://purl.obolibrary.org/obo/GO_0070849 denotes growth factor, and epidermal
T18028 261-289 http://purl.obolibrary.org/obo/GO_0007174 denotes growth factor, and epidermal
T18027 290-296 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T18026 261-267 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T18025 131-137 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T18024 20-50 http://purl.obolibrary.org/obo/GO_0042326 denotes phosphorylation and inhibition
T18023 1225-1240 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18022 1133-1148 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18021 827-842 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18020 20-35 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation

GO-CC

Id Subject Object Predicate Lexical cue
T18245 1114-1122 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T18244 1094-1102 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T18243 1114-1122 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T18242 1094-1102 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T18241 2438-2443 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18240 2074-2079 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18239 1888-1893 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18238 1803-1808 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18237 965-970 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18236 882-887 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18235 642-647 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18234 482-487 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18233 84-89 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

GO-MF

Id Subject Object Predicate Lexical cue
T18232 1333-1346 http://purl.obolibrary.org/obo/GO_0004915 denotes IL-6 activity
T18231 1114-1122 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T18230 1094-1102 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T18229 261-289 http://purl.obolibrary.org/obo/GO_0048408 denotes growth factor, and epidermal
T18228 261-289 http://purl.obolibrary.org/obo/GO_0005154 denotes growth factor, and epidermal
T18227 229-241 http://purl.obolibrary.org/obo/GO_0005147 denotes oncostatin M
T18226 190-195 http://purl.obolibrary.org/obo/GO_0005142 denotes IL-11
T18225 2419-2424 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18224 2229-2234 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18223 2088-2093 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18222 1978-1983 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18221 1759-1764 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18220 775-780 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18219 320-325 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18218 54-59 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18217 2309-2313 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18216 2184-2188 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18215 2046-2050 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18214 1855-1859 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18213 1725-1729 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18212 1557-1561 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18211 1386-1390 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18210 1333-1337 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18209 1089-1093 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18208 860-864 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18207 674-678 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18206 500-504 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18205 375-379 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18204 184-188 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18203 158-162 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18202 0-4 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6

sentences

Id Subject Object Predicate Lexical cue
T18019 2236-2444 Sentence denotes Taken together, these findings suggest that persistent exposure to serum IL-6 may have a role in both the induction of STAT3 activation and the resistance to the inhibitory effect of IL-10 in RA CD4+ T cells.
T18018 2046-2235 Sentence denotes IL-6 pretreatment of normal cells reduced IL-10-mediated inhibition of IFN-γ production (Fig. 5b), indicating that high concentrations of IL-6 could modulate T-cell responsiveness to IL-10.
T18017 1810-2045 Sentence denotes After preincubation with or without 10 ng/ml IL-6 for 36 hours, normal CD4+ T cells were stimulated by CD3 and CD28 costimulation in the presence or absence of 1 ng/ml IL-10 for 36 hours, and the IFN-γ production was measured by ELISA.
T18016 1700-1809 Sentence denotes We next examined whether IL-6 could suppress the effect of IL-10 to inhibit IFN-γ production by CD4+ T cells.
T18015 1472-1699 Sentence denotes The lack of STAT1 activation by RA serum suggests that much higher concentrations of IL-6 may be required for STAT1 activation as compared with STAT3 activation, or that inhibitors of STAT1 signaling may be present in RA serum.
T18014 1358-1471 Sentence denotes These results indicate that IL-6 is the dominant STAT3-activating factor contained in sera of active RA patients.
T18013 1188-1357 Sentence denotes RA serum was able to induce tyrosine phosphorylation of STAT3 but not STAT1, and this STAT3 activation was mostly abolished by neutralization of IL-6 activity (Fig. 5a).
T18012 951-1187 Sentence denotes Normal CD4+ T cells were thus incubated for 20 min with culture medium containing 30% serum from active RA patients and neutralizing anti-IL-6 antibody or control antibody, and STAT phosphorylation was examined by western blot analysis.
T18011 806-950 Sentence denotes Both STAT1 and STAT3 phosphorylation was activated by IL-6 in normal CD4+ T cells (data not shown), in agreement with previous observations [4].
T18010 494-805 Sentence denotes Since IL-6 is also abundant in sera of active RA patients, frequently detected at > 1 ng/ml [27], we examined whether persistent exposure of CD4+ T cells to high concentrations of IL-6 in the blood circulation was responsible for their sustained STAT3 activation and resistance to IL-10 inhibition in active RA.
T18009 90-493 Sentence denotes STAT3 is activated by many cytokines and growth factors such as the IL-6 family of cytokines (IL-6, IL-11, leukemia inhibitory factor, and oncostatin M), platelet-derived growth factor, and epidermal growth factor, in addition to IL-10 [4], but previous studies have demonstrated that IL-6 is the major factor in RA synovial fluid that induces constitutive activation of STAT3 in mononuclear cells [31].
T18008 0-89 Sentence denotes IL-6-mediated STAT3 phosphorylation and inhibition of IL-10 effect in normal CD4+ T cells
T119 0-89 Sentence denotes IL-6-mediated STAT3 phosphorylation and inhibition of IL-10 effect in normal CD4+ T cells
T120 90-493 Sentence denotes STAT3 is activated by many cytokines and growth factors such as the IL-6 family of cytokines (IL-6, IL-11, leukemia inhibitory factor, and oncostatin M), platelet-derived growth factor, and epidermal growth factor, in addition to IL-10 [4], but previous studies have demonstrated that IL-6 is the major factor in RA synovial fluid that induces constitutive activation of STAT3 in mononuclear cells [31].
T121 494-805 Sentence denotes Since IL-6 is also abundant in sera of active RA patients, frequently detected at > 1 ng/ml [27], we examined whether persistent exposure of CD4+ T cells to high concentrations of IL-6 in the blood circulation was responsible for their sustained STAT3 activation and resistance to IL-10 inhibition in active RA.
T122 806-950 Sentence denotes Both STAT1 and STAT3 phosphorylation was activated by IL-6 in normal CD4+ T cells (data not shown), in agreement with previous observations [4].
T123 951-1187 Sentence denotes Normal CD4+ T cells were thus incubated for 20 min with culture medium containing 30% serum from active RA patients and neutralizing anti-IL-6 antibody or control antibody, and STAT phosphorylation was examined by western blot analysis.
T124 1188-1357 Sentence denotes RA serum was able to induce tyrosine phosphorylation of STAT3 but not STAT1, and this STAT3 activation was mostly abolished by neutralization of IL-6 activity (Fig. 5a).
T125 1358-1471 Sentence denotes These results indicate that IL-6 is the dominant STAT3-activating factor contained in sera of active RA patients.
T126 1472-1699 Sentence denotes The lack of STAT1 activation by RA serum suggests that much higher concentrations of IL-6 may be required for STAT1 activation as compared with STAT3 activation, or that inhibitors of STAT1 signaling may be present in RA serum.
T127 1700-1809 Sentence denotes We next examined whether IL-6 could suppress the effect of IL-10 to inhibit IFN-γ production by CD4+ T cells.
T128 1810-2045 Sentence denotes After preincubation with or without 10 ng/ml IL-6 for 36 hours, normal CD4+ T cells were stimulated by CD3 and CD28 costimulation in the presence or absence of 1 ng/ml IL-10 for 36 hours, and the IFN-γ production was measured by ELISA.
T129 2046-2235 Sentence denotes IL-6 pretreatment of normal cells reduced IL-10-mediated inhibition of IFN-γ production (Fig. 5b), indicating that high concentrations of IL-6 could modulate T-cell responsiveness to IL-10.
T130 2236-2444 Sentence denotes Taken together, these findings suggest that persistent exposure to serum IL-6 may have a role in both the induction of STAT3 activation and the resistance to the inhibitory effect of IL-10 in RA CD4+ T cells.

simple1

Id Subject Object Predicate Lexical cue
T18494 2431-2434 Protein denotes CD4
T18493 2419-2424 Protein denotes IL-10
T18492 2355-2360 Protein denotes STAT3
T18491 2309-2313 Protein denotes IL-6
T18490 2229-2234 Protein denotes IL-10
T18489 2184-2188 Protein denotes IL-6
T18488 2117-2122 Protein denotes IFN-γ
T18487 2088-2093 Protein denotes IL-10
T18486 2046-2050 Protein denotes IL-6
T18485 2006-2011 Protein denotes IFN-γ
T18484 1978-1983 Protein denotes IL-10
T18483 1921-1925 Protein denotes CD28
T18482 1881-1884 Protein denotes CD4
T18481 1855-1859 Protein denotes IL-6
T18480 1796-1799 Protein denotes CD4
T18479 1776-1781 Protein denotes IFN-γ
T18478 1759-1764 Protein denotes IL-10
T18477 1725-1729 Protein denotes IL-6
T18476 1656-1661 Protein denotes STAT1
T18475 1616-1621 Protein denotes STAT3
T18474 1582-1587 Protein denotes STAT1
T18473 1557-1561 Protein denotes IL-6
T18472 1484-1489 Protein denotes STAT1
T18471 1407-1412 Protein denotes STAT3
T18470 1386-1390 Protein denotes IL-6
T18469 1333-1337 Protein denotes IL-6
T18468 1274-1279 Protein denotes STAT3
T18467 1258-1263 Protein denotes STAT1
T18466 1244-1249 Protein denotes STAT3
T18465 1089-1093 Protein denotes IL-6
T18464 958-961 Protein denotes CD4
T18463 875-878 Protein denotes CD4
T18462 860-864 Protein denotes IL-6
T18461 821-826 Protein denotes STAT3
T18460 811-816 Protein denotes STAT1
T18459 775-780 Protein denotes IL-10
T18458 740-745 Protein denotes STAT3
T18457 674-678 Protein denotes IL-6
T18456 635-638 Protein denotes CD4
T18455 500-504 Protein denotes IL-6
T18454 461-466 Protein denotes STAT3
T18453 375-379 Protein denotes IL-6
T18452 320-325 Protein denotes IL-10
T18451 280-303 Protein denotes epidermal growth factor
T18450 244-274 Protein denotes platelet-derived growth factor
T18449 229-241 Protein denotes oncostatin M
T18448 197-223 Protein denotes leukemia inhibitory factor
T18447 190-195 Protein denotes IL-11
T18446 184-188 Protein denotes IL-6
T18445 90-95 Protein denotes STAT3
T18444 77-80 Protein denotes CD4
T18443 54-59 Protein denotes IL-10
T18442 14-19 Protein denotes STAT3
T18441 0-4 Protein denotes IL-6

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T19832 1407-1412 Protein denotes STAT3
T19831 1386-1390 Protein denotes IL-6
T19830 1333-1337 Protein denotes IL-6
T19829 1274-1279 Protein denotes STAT3
T19828 1258-1263 Protein denotes STAT1
T19827 1244-1249 Protein denotes STAT3
T19826 1089-1093 Protein denotes IL-6
T19825 958-961 Protein denotes CD4
T19824 875-878 Protein denotes CD4
T19823 860-864 Protein denotes IL-6
T19822 821-826 Protein denotes STAT3
T19821 811-816 Protein denotes STAT1
T19820 775-780 Protein denotes IL-10
T19819 740-745 Protein denotes STAT3
T19818 674-678 Protein denotes IL-6
T19817 635-638 Protein denotes CD4
T19816 500-504 Protein denotes IL-6
T19815 229-241 Protein denotes oncostatin M
T19814 197-223 Protein denotes leukemia inhibitory factor
T19813 190-195 Protein denotes IL-11
T19812 184-188 Protein denotes IL-6
T19811 90-95 Protein denotes STAT3
T19810 461-466 Protein denotes STAT3
T19809 375-379 Protein denotes IL-6
T19808 320-325 Protein denotes IL-10
T19807 280-303 Protein denotes epidermal growth factor
T19806 244-274 Protein denotes platelet-derived growth factor
T19805 77-80 Protein denotes CD4
T19804 54-59 Protein denotes IL-10
T19803 14-19 Protein denotes STAT3
T19802 0-4 Protein denotes IL-6
T19885 2361-2371 Positive_regulation denotes activation
T19884 2342-2351 Positive_regulation denotes induction
T19883 2123-2133 Gene_expression denotes production
T19882 2103-2113 Negative_regulation denotes inhibition
T19881 2012-2022 Gene_expression denotes production
T19880 1782-1792 Gene_expression denotes production
T19879 1768-1775 Negative_regulation denotes inhibit
T19878 1588-1598 Positive_regulation denotes activation
T19877 1622-1632 Positive_regulation denotes activation
T19876 1476-1480 Negative_regulation denotes lack
T19875 1490-1500 Positive_regulation denotes activation
T19874 1569-1577 Positive_regulation denotes required
T19873 1280-1290 Positive_regulation denotes activation
T19872 1209-1215 Positive_regulation denotes induce
T19871 1315-1329 Negative_regulation denotes neutralization
T19870 1225-1240 Phosphorylation denotes phosphorylation
T19869 1302-1311 Negative_regulation denotes abolished
T19868 827-842 Phosphorylation denotes phosphorylation
T19867 847-856 Positive_regulation denotes activated
T19866 781-791 Negative_regulation denotes inhibition
T19865 708-719 Positive_regulation denotes responsible
T19864 746-756 Positive_regulation denotes activation
T19863 564-572 Gene_expression denotes detected
T19862 426-433 Positive_regulation denotes induces
T19861 447-457 Positive_regulation denotes activation
T19860 99-108 Positive_regulation denotes activated
T19859 60-66 Regulation denotes effect
T19858 5-13 Positive_regulation denotes mediated
T19857 40-50 Negative_regulation denotes inhibition
T19856 20-35 Phosphorylation denotes phosphorylation
T19855 2431-2434 Protein denotes CD4
T19854 2419-2424 Protein denotes IL-10
T19853 2355-2360 Protein denotes STAT3
T19852 2309-2313 Protein denotes IL-6
T19851 2229-2234 Protein denotes IL-10
T19850 2184-2188 Protein denotes IL-6
T19849 2117-2122 Protein denotes IFN-γ
T19848 2088-2093 Protein denotes IL-10
T19847 2046-2050 Protein denotes IL-6
T19846 2006-2011 Protein denotes IFN-γ
T19845 1978-1983 Protein denotes IL-10
T19844 1921-1925 Protein denotes CD28
T19843 1881-1884 Protein denotes CD4
T19842 1855-1859 Protein denotes IL-6
T19841 1796-1799 Protein denotes CD4
T19840 1776-1781 Protein denotes IFN-γ
T19839 1759-1764 Protein denotes IL-10
T19838 1725-1729 Protein denotes IL-6
T19837 1656-1661 Protein denotes STAT1
T19836 1616-1621 Protein denotes STAT3
T19835 1582-1587 Protein denotes STAT1
T19834 1557-1561 Protein denotes IL-6
T19833 1484-1489 Protein denotes STAT1
R10063 T19835 T19878 themeOf STAT1,activation
R10064 T19836 T19877 themeOf STAT3,activation
R10065 T19840 T19880 themeOf IFN-γ,production
R10066 T19846 T19881 themeOf IFN-γ,production
R10067 T19849 T19883 themeOf IFN-γ,production
R10068 T19853 T19885 themeOf STAT3,activation
R10071 T19861 T19862 themeOf activation,induces
R10072 T19864 T19865 themeOf activation,responsible
R10073 T19868 T19867 themeOf phosphorylation,activated
R10074 T19868 T19867 themeOf phosphorylation,activated
R10075 T19870 T19872 themeOf phosphorylation,induce
R10076 T19870 T19872 themeOf phosphorylation,induce
R10077 T19873 T19869 themeOf activation,abolished
R10078 T19875 T19876 themeOf activation,lack
R10079 T19878 T19874 themeOf activation,required
R10080 T19880 T19879 themeOf production,inhibit
R10081 T19883 T19882 themeOf production,inhibition
R10082 T19885 T19884 themeOf activation,induction
R10039 T19803 T19858 themeOf STAT3,mediated
R10040 T19803 T19856 themeOf STAT3,phosphorylation
R10041 T19804 T19859 themeOf IL-10,effect
R10042 T19808 T19860 themeOf IL-10,activated
R10069 T19856 T19858 themeOf phosphorylation,mediated
R10070 T19859 T19857 themeOf effect,inhibition
R10043 T19810 T19861 themeOf STAT3,activation
R10044 T19811 T19860 themeOf STAT3,activated
R10045 T19814 T19860 causeOf leukemia inhibitory factor,activated
R10046 T19814 T19860 causeOf leukemia inhibitory factor,activated
R10047 T19816 T19863 themeOf IL-6,detected
R10048 T19819 T19864 themeOf STAT3,activation
R10049 T19820 T19866 themeOf IL-10,inhibition
R10050 T19821 T19868 themeOf STAT1,phosphorylation
R10051 T19821 T19867 themeOf STAT1,activated
R10052 T19822 T19868 themeOf STAT3,phosphorylation
R10053 T19822 T19867 themeOf STAT3,activated
R10054 T19823 T19867 causeOf IL-6,activated
R10055 T19823 T19867 causeOf IL-6,activated
R10056 T19823 T19867 causeOf IL-6,activated
R10057 T19823 T19867 causeOf IL-6,activated
R10058 T19827 T19870 themeOf STAT3,phosphorylation
R10059 T19828 T19870 themeOf STAT1,phosphorylation
R10060 T19829 T19873 themeOf STAT3,activation
R10061 T19830 T19871 themeOf IL-6,neutralization
R10062 T19833 T19875 themeOf STAT1,activation

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T19004 2342-2351 Positive_regulation denotes induction
T19003 2325-2329 Regulation denotes role
T19002 2361-2371 Positive_regulation denotes activation
T19001 2094-2102 Positive_regulation denotes mediated
T18974 5-13 Positive_regulation denotes mediated
T18973 40-50 Negative_regulation denotes inhibition
T18972 60-66 Regulation denotes effect
T18971 20-35 Phosphorylation denotes phosphorylation
T18970 2431-2434 Protein denotes CD4
T18969 2419-2424 Protein denotes IL-10
T18968 2355-2360 Protein denotes STAT3
T18967 2309-2313 Protein denotes IL-6
T18966 2229-2234 Protein denotes IL-10
T18965 2184-2188 Protein denotes IL-6
T18964 2117-2122 Protein denotes IFN-γ
T18963 2088-2093 Protein denotes IL-10
T18962 2046-2050 Protein denotes IL-6
T18961 2006-2011 Protein denotes IFN-γ
T18960 1978-1983 Protein denotes IL-10
T18959 1921-1925 Protein denotes CD28
T18958 1881-1884 Protein denotes CD4
T18957 1855-1859 Protein denotes IL-6
T18956 1796-1799 Protein denotes CD4
T18955 1776-1781 Protein denotes IFN-γ
T18954 1759-1764 Protein denotes IL-10
T18953 1725-1729 Protein denotes IL-6
T18952 1656-1661 Protein denotes STAT1
T18951 1616-1621 Protein denotes STAT3
T18950 1582-1587 Protein denotes STAT1
T18949 1557-1561 Protein denotes IL-6
T18948 1484-1489 Protein denotes STAT1
T18947 1407-1412 Protein denotes STAT3
T18946 1386-1390 Protein denotes IL-6
T18945 1333-1337 Protein denotes IL-6
T18944 1274-1279 Protein denotes STAT3
T18943 1258-1263 Protein denotes STAT1
T18942 1244-1249 Protein denotes STAT3
T18941 1089-1093 Protein denotes IL-6
T18940 958-961 Protein denotes CD4
T18939 875-878 Protein denotes CD4
T18938 860-864 Protein denotes IL-6
T18937 821-826 Protein denotes STAT3
T18936 811-816 Protein denotes STAT1
T18935 775-780 Protein denotes IL-10
T18934 740-745 Protein denotes STAT3
T18933 674-678 Protein denotes IL-6
T18932 635-638 Protein denotes CD4
T18931 500-504 Protein denotes IL-6
T18930 229-241 Protein denotes oncostatin M
T18929 197-223 Protein denotes leukemia inhibitory factor
T18928 190-195 Protein denotes IL-11
T18927 184-188 Protein denotes IL-6
T18926 90-95 Protein denotes STAT3
T18925 461-466 Protein denotes STAT3
T18924 375-379 Protein denotes IL-6
T18923 320-325 Protein denotes IL-10
T18922 280-303 Protein denotes epidermal growth factor
T18921 244-274 Protein denotes platelet-derived growth factor
T18920 77-80 Protein denotes CD4
T18919 54-59 Protein denotes IL-10
T18918 14-19 Protein denotes STAT3
T18917 0-4 Protein denotes IL-6
T18991 1588-1598 Positive_regulation denotes activation
T18990 1622-1632 Positive_regulation denotes activation
T18989 1476-1480 Negative_regulation denotes lack
T18988 1209-1215 Positive_regulation denotes induce
T18987 1302-1311 Negative_regulation denotes abolished
T18986 1225-1240 Phosphorylation denotes phosphorylation
T18985 1280-1290 Positive_regulation denotes activation
T18984 1315-1329 Negative_regulation denotes neutralization
T18983 827-842 Phosphorylation denotes phosphorylation
T18982 847-856 Positive_regulation denotes activated
T18981 708-719 Positive_regulation denotes responsible
T18980 781-791 Negative_regulation denotes inhibition
T18979 730-739 Positive_regulation denotes sustained
T18978 746-756 Positive_regulation denotes activation
T18977 99-108 Positive_regulation denotes activated
T18976 426-433 Positive_regulation denotes induces
T18975 447-457 Positive_regulation denotes activation
T19000 2103-2113 Negative_regulation denotes inhibition
T18999 2123-2133 Gene_expression denotes production
T18998 2080-2087 Negative_regulation denotes reduced
T18997 2012-2022 Gene_expression denotes production
T18996 1749-1755 Regulation denotes effect
T18995 1768-1775 Negative_regulation denotes inhibit
T18994 1782-1792 Gene_expression denotes production
T18993 1490-1500 Positive_regulation denotes activation
T18992 1569-1577 Positive_regulation denotes required
R9398 T18917 T18974 causeOf IL-6,mediated
R9399 T18918 T18971 themeOf STAT3,phosphorylation
R9400 T18919 T18972 themeOf IL-10,effect
R9401 T18923 T18977 themeOf IL-10,activated
R9402 T18925 T18975 themeOf STAT3,activation
R9403 T18926 T18977 themeOf STAT3,activated
R9404 T18934 T18978 themeOf STAT3,activation
R9405 T18935 T18980 themeOf IL-10,inhibition
R9406 T18936 T18983 themeOf STAT1,phosphorylation
R9407 T18936 T18982 themeOf STAT1,activated
R9408 T18937 T18983 themeOf STAT3,phosphorylation
R9409 T18937 T18982 themeOf STAT3,activated
R9410 T18938 T18982 causeOf IL-6,activated
R9411 T18938 T18982 causeOf IL-6,activated
R9412 T18942 T18986 themeOf STAT3,phosphorylation
R9413 T18943 T18986 themeOf STAT1,phosphorylation
R9414 T18944 T18985 themeOf STAT3,activation
R9415 T18945 T18984 themeOf IL-6,neutralization
R9416 T18948 T18993 themeOf STAT1,activation
R9417 T18950 T18991 themeOf STAT1,activation
R9418 T18951 T18990 themeOf STAT3,activation
R9419 T18954 T18996 themeOf IL-10,effect
R9420 T18955 T18994 themeOf IFN-γ,production
R9421 T18961 T18997 themeOf IFN-γ,production
R9422 T18963 T19001 themeOf IL-10,mediated
R9423 T18964 T18999 themeOf IFN-γ,production
R9424 T18968 T19002 themeOf STAT3,activation
R9425 T18971 T18974 themeOf phosphorylation,mediated
R9426 T18972 T18973 themeOf effect,inhibition
R9427 T18975 T18976 themeOf activation,induces
R9428 T18978 T18981 themeOf activation,responsible
R9429 T18978 T18979 themeOf activation,sustained
R9430 T18985 T18987 themeOf activation,abolished
R9431 T18986 T18988 themeOf phosphorylation,induce
R9432 T18986 T18988 themeOf phosphorylation,induce
R9433 T18991 T18992 themeOf activation,required
R9434 T18993 T18989 themeOf activation,lack
R9435 T18994 T18995 themeOf production,inhibit
R9436 T18999 T19000 themeOf production,inhibition
R9437 T19000 T18998 themeOf inhibition,reduced
R9438 T19001 T18998 themeOf mediated,reduced
R9439 T19002 T19004 themeOf activation,induction
R9440 T19004 T19003 themeOf induction,role

DLUT931

Id Subject Object Predicate Lexical cue
T19452 375-379 Protein denotes IL-6
T19451 320-325 Protein denotes IL-10
T19450 280-303 Protein denotes epidermal growth factor
T19449 244-274 Protein denotes platelet-derived growth factor
T19448 77-80 Protein denotes CD4
T19447 54-59 Protein denotes IL-10
T19446 14-19 Protein denotes STAT3
T19445 0-4 Protein denotes IL-6
T19537 2325-2329 Regulation denotes role
T19536 2342-2351 Positive_regulation denotes induction
T19535 2361-2371 Positive_regulation denotes activation
T19534 2094-2102 Positive_regulation denotes mediated
T19533 2080-2087 Negative_regulation denotes reduced
T19532 2195-2203 Regulation denotes modulate
T19531 2103-2113 Negative_regulation denotes inhibition
T19530 2211-2225 Positive_regulation denotes responsiveness
T19529 2123-2133 Gene_expression denotes production
T19528 1899-1909 Positive_regulation denotes stimulated
T19527 2012-2022 Gene_expression denotes production
T19526 1749-1755 Regulation denotes effect
T19525 1768-1775 Negative_regulation denotes inhibit
T19524 1782-1792 Gene_expression denotes production
T19523 1569-1577 Positive_regulation denotes required
T19522 1476-1480 Negative_regulation denotes lack
T19521 1642-1652 Negative_regulation denotes inhibitors
T19520 1622-1632 Positive_regulation denotes activation
T19519 1588-1598 Positive_regulation denotes activation
T19518 1490-1500 Positive_regulation denotes activation
T19517 1413-1423 Positive_regulation denotes activating
T19516 1209-1215 Positive_regulation denotes induce
T19515 1302-1311 Negative_regulation denotes abolished
T19514 1280-1290 Positive_regulation denotes activation
T19513 1225-1240 Phosphorylation denotes phosphorylation
T19512 847-856 Positive_regulation denotes activated
T19511 827-842 Phosphorylation denotes phosphorylation
T19510 761-771 Positive_regulation denotes resistance
T19509 730-739 Positive_regulation denotes sustained
T19508 708-719 Positive_regulation denotes responsible
T19507 781-791 Negative_regulation denotes inhibition
T19506 746-756 Positive_regulation denotes activation
T19505 564-572 Gene_expression denotes detected
T19504 426-433 Positive_regulation denotes induces
T19503 447-457 Positive_regulation denotes activation
T19502 99-108 Positive_regulation denotes activated
T19501 5-13 Positive_regulation denotes mediated
T19500 60-66 Regulation denotes effect
T19499 20-35 Phosphorylation denotes phosphorylation
T19498 2431-2434 Protein denotes CD4
T19497 2419-2424 Protein denotes IL-10
T19496 2355-2360 Protein denotes STAT3
T19492 2117-2122 Protein denotes IFN-γ
T19491 2088-2093 Protein denotes IL-10
T19490 2046-2050 Protein denotes IL-6
T19489 2006-2011 Protein denotes IFN-γ
T19488 1978-1983 Protein denotes IL-10
T19487 1921-1925 Protein denotes CD28
T19486 1881-1884 Protein denotes CD4
T19485 1855-1859 Protein denotes IL-6
T19484 1796-1799 Protein denotes CD4
T19483 1776-1781 Protein denotes IFN-γ
T19482 1759-1764 Protein denotes IL-10
T19481 1725-1729 Protein denotes IL-6
T19480 1656-1661 Protein denotes STAT1
T19479 1616-1621 Protein denotes STAT3
T19478 1582-1587 Protein denotes STAT1
T19477 1557-1561 Protein denotes IL-6
T19476 1484-1489 Protein denotes STAT1
T19475 1407-1412 Protein denotes STAT3
T19474 1386-1390 Protein denotes IL-6
T19473 1333-1337 Protein denotes IL-6
T19472 1274-1279 Protein denotes STAT3
T19471 1258-1263 Protein denotes STAT1
T19470 1244-1249 Protein denotes STAT3
T19469 1089-1093 Protein denotes IL-6
T19468 958-961 Protein denotes CD4
T19467 875-878 Protein denotes CD4
T19466 860-864 Protein denotes IL-6
T19465 821-826 Protein denotes STAT3
T19464 811-816 Protein denotes STAT1
T19463 775-780 Protein denotes IL-10
T19462 740-745 Protein denotes STAT3
T19461 674-678 Protein denotes IL-6
T19460 635-638 Protein denotes CD4
T19459 500-504 Protein denotes IL-6
T19458 229-241 Protein denotes oncostatin M
T19457 197-223 Protein denotes leukemia inhibitory factor
T19456 190-195 Protein denotes IL-11
T19455 184-188 Protein denotes IL-6
T19454 90-95 Protein denotes STAT3
T19453 461-466 Protein denotes STAT3
T19494 2229-2234 Protein denotes IL-10
T19493 2184-2188 Protein denotes IL-6
T19495 2309-2313 Protein denotes IL-6
R9881 T19445 T19501 causeOf IL-6,mediated
R9882 T19446 T19499 themeOf STAT3,phosphorylation
R9883 T19447 T19500 themeOf IL-10,effect
R9884 T19451 T19502 themeOf IL-10,activated
R9885 T19452 T19504 causeOf IL-6,induces
R9886 T19453 T19503 themeOf STAT3,activation
R9887 T19454 T19502 themeOf STAT3,activated
R9888 T19459 T19505 themeOf IL-6,detected
R9889 T19462 T19506 themeOf STAT3,activation
R9890 T19463 T19507 themeOf IL-10,inhibition
R9891 T19464 T19511 themeOf STAT1,phosphorylation
R9892 T19464 T19512 themeOf STAT1,activated
R9893 T19465 T19511 themeOf STAT3,phosphorylation
R9894 T19465 T19512 themeOf STAT3,activated
R9895 T19466 T19512 causeOf IL-6,activated
R9896 T19466 T19512 causeOf IL-6,activated
R9897 T19466 T19512 causeOf IL-6,activated
R9898 T19466 T19512 causeOf IL-6,activated
R9899 T19470 T19513 themeOf STAT3,phosphorylation
R9900 T19471 T19513 themeOf STAT1,phosphorylation
R9901 T19472 T19514 themeOf STAT3,activation
R9902 T19474 T19517 causeOf IL-6,activating
R9903 T19475 T19517 themeOf STAT3,activating
R9904 T19476 T19518 themeOf STAT1,activation
R9905 T19478 T19519 themeOf STAT1,activation
R9906 T19479 T19520 themeOf STAT3,activation
R9907 T19480 T19521 themeOf STAT1,inhibitors
R9908 T19482 T19526 causeOf IL-10,effect
R9909 T19483 T19524 themeOf IFN-γ,production
R9910 T19489 T19527 themeOf IFN-γ,production
R9911 T19491 T19534 causeOf IL-10,mediated
R9912 T19492 T19529 themeOf IFN-γ,production
R9913 T19494 T19530 themeOf IL-10,responsiveness
R9914 T19496 T19535 themeOf STAT3,activation
R9915 T19499 T19501 themeOf phosphorylation,mediated
R9916 T19503 T19504 themeOf activation,induces
R9917 T19506 T19508 themeOf activation,responsible
R9918 T19506 T19509 themeOf activation,sustained
R9919 T19507 T19510 themeOf inhibition,resistance
R9920 T19511 T19512 themeOf phosphorylation,activated
R9921 T19511 T19512 themeOf phosphorylation,activated
R9922 T19513 T19516 themeOf phosphorylation,induce
R9923 T19513 T19516 themeOf phosphorylation,induce
R9924 T19514 T19515 themeOf activation,abolished
R9925 T19518 T19522 themeOf activation,lack
R9926 T19519 T19523 themeOf activation,required
R9927 T19524 T19525 themeOf production,inhibit
R9928 T19525 T19526 themeOf inhibit,effect
R9929 T19527 T19528 themeOf production,stimulated
R9930 T19529 T19531 themeOf production,inhibition
R9931 T19530 T19532 themeOf responsiveness,modulate
R9932 T19531 T19533 themeOf inhibition,reduced
R9933 T19531 T19534 themeOf inhibition,mediated
R9934 T19534 T19531 themeOf mediated,inhibition
R9935 T19535 T19536 themeOf activation,induction
R9936 T19536 T19537 themeOf induction,role

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue Speculation
T19801 775-804 Negative_regulation denotes IL-10 inhibition in active RA
T19800 14-35 Phosphorylation denotes STAT3 phosphorylation
T19799 1768-1799 Negative_regulation denotes inhibit IFN-γ production by CD4
T19798 1611-1632 Positive_regulation denotes with STAT3 activation
T19797 1128-1186 Phosphorylation denotes STAT phosphorylation was examined by western blot analysis
T19796 434-492 Positive_regulation denotes constitutive activation of STAT3 in mononuclear cells [31]
T19795 1216-1263 Phosphorylation denotes tyrosine phosphorylation of STAT3 but not STAT1
T19794 90-108 Positive_regulation denotes STAT3 is activated
T19793 1656-1671 Positive_regulation denotes STAT1 signaling
T19792 2352-2371 Positive_regulation denotes of STAT3 activation
T19791 1725-1799 Negative_regulation denotes IL-6 could suppress the effect of IL-10 to inhibit IFN-γ production by CD4 true
T19790 2117-2133 Gene_expression denotes IFN-γ production
T19789 1269-1290 Positive_regulation denotes this STAT3 activation
T19788 40-80 Negative_regulation denotes inhibition of IL-10 effect in normal CD4
T19787 1481-1500 Positive_regulation denotes of STAT1 activation
T19786 1776-1799 Gene_expression denotes IFN-γ production by CD4
T19785 1921-1939 Positive_regulation denotes CD28 costimulation
T19745 963-970 Entity denotes T cells
T19744 470-492 Entity denotes mononuclear cells [31]
T19743 70-80 Protein denotes normal CD4
T19742 1258-1263 Protein denotes STAT1
T19741 740-745 Protein denotes STAT3
T19740 1616-1621 Protein denotes STAT3
T19739 2135-2138 Protein denotes Fig
T19738 1333-1337 Protein denotes IL-6
T19737 1484-1489 Protein denotes STAT1
T19736 82-89 Entity denotes T cells
T19735 2046-2050 Protein denotes IL-6
T19734 2067-2079 Entity denotes normal cells
T19733 0-4 Protein denotes IL-6
T19732 1348-1351 Protein denotes Fig
T19731 540-542 Protein denotes RA
T19730 821-826 Protein denotes STAT3
T19729 1084-1122 Entity denotes anti-IL-6 antibody or control antibody
T19728 2117-2122 Protein denotes IFN-γ
T19727 14-19 Protein denotes STAT3
T19726 671-678 Protein denotes of IL-6
T19725 2088-2102 Protein denotes IL-10-mediated
T19724 2006-2011 Protein denotes IFN-γ
T19723 2355-2360 Protein denotes STAT3
T19722 1846-1873 Protein denotes 10 ng/ml IL-6 for 36 hours,
T19721 280-303 Protein denotes epidermal growth factor
T19720 1656-1661 Protein denotes STAT1
T19719 2416-2424 Protein denotes of IL-10
T19718 54-59 Protein denotes IL-10
T19717 775-780 Protein denotes IL-10
T19716 184-188 Protein denotes IL-6
T19715 1582-1587 Protein denotes STAT1
T19714 1913-1916 Protein denotes CD3
T19713 1637-1671 Entity denotes that inhibitors of STAT1 signaling
T19712 1241-1249 Protein denotes of STAT3
T19711 868-904 Entity denotes normal CD4+ T cells (data not shown)
T19710 403-405 Protein denotes RA
T19709 500-504 Protein denotes IL-6
T19708 1874-1893 Entity denotes normal CD4+ T cells
T19707 229-241 Protein denotes oncostatin M
T19706 90-95 Protein denotes STAT3
T19705 857-864 Protein denotes by IL-6
T19704 1793-1799 Protein denotes by CD4
T19703 525-552 Protein denotes sera of active RA patients,
T19784 2002-2022 Gene_expression denotes the IFN-γ production
T19783 1582-1598 Positive_regulation denotes STAT1 activation
T19782 2088-2113 Regulation denotes IL-10-mediated inhibition
T19781 1444-1470 Protein denotes sera of active RA patients
T19780 320-330 Protein denotes IL-10 [4],
T19779 375-379 Protein denotes IL-6
T19778 951-961 Protein denotes Normal CD4
T19777 1094-1102 Entity denotes antibody
T19776 173-242 Protein denotes cytokines (IL-6, IL-11, leukemia inhibitory factor, and oncostatin M)
T19775 2226-2234 Protein denotes to IL-10
T19774 2181-2188 Protein denotes of IL-6
T19773 1725-1729 Protein denotes IL-6
T19772 1967-1997 Protein denotes of 1 ng/ml IL-10 for 36 hours,
T19771 1128-1132 Protein denotes STAT
T19770 2309-2313 Protein denotes IL-6
T19769 1554-1561 Protein denotes of IL-6
T19768 197-223 Protein denotes leukemia inhibitory factor
T19767 1756-1764 Protein denotes of IL-10
T19766 632-647 Entity denotes of CD4+ T cells
T19765 1921-1925 Protein denotes CD28
T19764 458-466 Protein denotes of STAT3
T19763 1386-1390 Protein denotes IL-6
T19762 244-274 Protein denotes platelet-derived growth factor
T19761 1690-1692 Entity denotes RA
T19760 190-195 Protein denotes IL-11
T19759 2428-2443 Entity denotes RA CD4+ T cells
T19758 1055-1057 Protein denotes RA
T19757 1801-1808 Entity denotes T cells
T19756 1274-1279 Protein denotes STAT3
T19755 158-162 Protein denotes IL-6
T19754 1216-1224 Entity denotes tyrosine
T19753 1501-1506 Protein denotes by RA
T19752 795-804 Protein denotes active RA
T19751 1459-1461 Protein denotes RA
T19750 811-816 Protein denotes STAT1
T19749 2428-2430 Protein denotes RA
T19748 2204-2210 Entity denotes T-cell
T19747 1188-1190 Protein denotes RA
T19746 1776-1781 Protein denotes IFN-γ
R10018 T19706 T19794 themeOf STAT3,STAT3 is activated
R10019 T19712 T19795 themeOf of STAT3,tyrosine phosphorylation of STAT3 but not STAT1
R10020 T19715 T19783 themeOf STAT1,STAT1 activation
R10021 T19717 T19801 themeOf IL-10,IL-10 inhibition in active RA
R10022 T19720 T19793 causeOf STAT1,STAT1 signaling
R10023 T19723 T19792 themeOf STAT3,of STAT3 activation
R10024 T19724 T19784 themeOf IFN-γ,the IFN-γ production
R10025 T19725 T19782 causeOf IL-10-mediated,IL-10-mediated inhibition
R10026 T19727 T19800 themeOf STAT3,STAT3 phosphorylation
R10027 T19728 T19790 themeOf IFN-γ,IFN-γ production
R10028 T19737 T19787 themeOf STAT1,of STAT1 activation
R10029 T19740 T19798 themeOf STAT3,with STAT3 activation
R10030 T19746 T19786 themeOf IFN-γ,IFN-γ production by CD4
R10031 T19754 T19712 partOf tyrosine,of STAT3
R10032 T19754 T19795 siteOf tyrosine,tyrosine phosphorylation of STAT3 but not STAT1
R10033 T19756 T19789 themeOf STAT3,this STAT3 activation
R10034 T19764 T19796 themeOf of STAT3,constitutive activation of STAT3 in mononuclear cells [31]
R10035 T19765 T19785 themeOf CD28,CD28 costimulation
R10036 T19771 T19797 themeOf STAT,STAT phosphorylation was examined by western blot analysis
R10037 T19773 T19791 causeOf IL-6,IL-6 could suppress the effect of IL-10 to inhibit IFN-γ production by CD4
R10038 T19786 T19799 themeOf IFN-γ production by CD4,inhibit IFN-γ production by CD4

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T19444 2443-2444 . denotes .
T19443 2438-2443 NNS denotes cells
T19442 2436-2437 NNP denotes T
T19441 2434-2435 VBD denotes +
T19440 2431-2434 NNP denotes CD4
T19439 2428-2430 NNP denotes RA
T19438 2425-2427 IN denotes in
T19437 2419-2424 NN denotes IL-10
T19436 2416-2418 IN denotes of
T19435 2409-2415 NN denotes effect
T19434 2398-2408 JJ denotes inhibitory
T19433 2394-2397 DT denotes the
T19432 2391-2393 TO denotes to
T19431 2380-2390 NN denotes resistance
T19430 2376-2379 DT denotes the
T19429 2372-2375 CC denotes and
T19428 2361-2371 NN denotes activation
T19427 2355-2360 CD denotes STAT3
T19426 2352-2354 IN denotes of
T19425 2342-2351 NN denotes induction
T19424 2338-2341 DT denotes the
T19423 2333-2337 DT denotes both
T19422 2330-2332 IN denotes in
T19421 2325-2329 NN denotes role
T19420 2323-2324 DT denotes a
T19419 2318-2322 VB denotes have
T19418 2314-2317 MD denotes may
T19417 2309-2313 NNP denotes IL-6
T19416 2303-2308 VB denotes serum
T19415 2300-2302 TO denotes to
T19414 2291-2299 NN denotes exposure
T19413 2280-2290 JJ denotes persistent
T19412 2275-2279 IN denotes that
T19411 2267-2274 VBP denotes suggest
T19410 2258-2266 NNS denotes findings
T19409 2252-2257 DT denotes these
T19408 2250-2251 , denotes ,
T19407 2242-2250 RB denotes together
T19406 2236-2241 VBN denotes Taken
T19405 2234-2235 . denotes .
T19404 2229-2234 NNP denotes IL-10
T19403 2226-2228 TO denotes to
T19402 2211-2225 NN denotes responsiveness
T19401 2204-2210 NNP denotes T-cell
T19400 2195-2203 VB denotes modulate
T19399 2189-2194 MD denotes could
T19398 2184-2188 NN denotes IL-6
T19397 2181-2183 IN denotes of
T19396 2166-2180 NNS denotes concentrations
T19395 2161-2165 JJ denotes high
T19394 2156-2160 IN denotes that
T19393 2145-2155 VBG denotes indicating
T19392 2143-2144 , denotes ,
T19391 2142-2143 -RRB- denotes )
T19390 2140-2142 CD denotes 5b
T19389 2135-2139 NNP denotes Fig.
T19388 2134-2135 -LRB- denotes (
T19387 2123-2133 NN denotes production
T19386 2117-2122 JJ denotes IFN-γ
T19385 2114-2116 IN denotes of
T19384 2103-2113 NN denotes inhibition
T19383 2088-2102 JJ denotes IL-10-mediated
T19382 2080-2087 VBN denotes reduced
T19381 2074-2079 NNS denotes cells
T19380 2067-2073 JJ denotes normal
T19379 2064-2066 IN denotes of
T19378 2051-2063 NN denotes pretreatment
T19377 2046-2050 CD denotes IL-6
T19376 2044-2045 . denotes .
T19375 2039-2044 NNP denotes ELISA
T19374 2036-2038 IN denotes by
T19373 2027-2035 VBN denotes measured
T19372 2023-2026 VBD denotes was
T19371 2012-2022 NN denotes production
T19370 2006-2011 JJ denotes IFN-γ
T19369 2002-2005 DT denotes the
T19368 1998-2001 CC denotes and
T19367 1996-1997 , denotes ,
T19366 1991-1996 NNS denotes hours
T19365 1988-1990 CD denotes 36
T19364 1984-1987 IN denotes for
T19363 1978-1983 NN denotes IL-10
T19362 1972-1977 NN denotes ng/ml
T19361 1970-1971 CD denotes 1
T19360 1967-1969 IN denotes of
T19359 1959-1966 NN denotes absence
T19358 1956-1958 CC denotes or
T19357 1947-1955 NN denotes presence
T19356 1943-1946 DT denotes the
T19355 1940-1942 IN denotes in
T19354 1926-1939 NN denotes costimulation
T19353 1921-1925 NNP denotes CD28
T19352 1917-1920 CC denotes and
T19351 1913-1916 NNP denotes CD3
T19350 1910-1912 IN denotes by
T19349 1899-1909 VBN denotes stimulated
T19348 1894-1898 VBD denotes were
T19347 1888-1893 NNS denotes cells
T19346 1886-1887 NNP denotes T
T19345 1884-1885 CD denotes +
T19344 1881-1884 NNP denotes CD4
T19343 1874-1880 JJ denotes normal
T19342 1872-1873 , denotes ,
T19341 1867-1872 NNS denotes hours
T19340 1864-1866 CD denotes 36
T19339 1860-1863 IN denotes for
T19338 1855-1859 NN denotes IL-6
T19337 1849-1854 NN denotes ng/ml
T19336 1846-1848 CD denotes 10
T19335 1838-1845 IN denotes without
T19334 1835-1837 CC denotes or
T19333 1830-1834 IN denotes with
T19332 1816-1829 NN denotes preincubation
T19331 1810-1815 IN denotes After
T19330 1808-1809 . denotes .
T19329 1803-1808 NNS denotes cells
T19328 1801-1802 NNP denotes T
T19327 1799-1800 NNP denotes +
T19326 1796-1799 NNP denotes CD4
T19325 1793-1795 IN denotes by
T19324 1782-1792 NN denotes production
T19323 1776-1781 JJ denotes IFN-γ
T19322 1768-1775 VB denotes inhibit
T19321 1765-1767 TO denotes to
T19320 1759-1764 NN denotes IL-10
T19319 1756-1758 IN denotes of
T19318 1749-1755 NN denotes effect
T19317 1745-1748 DT denotes the
T19316 1736-1744 VB denotes suppress
T19315 1730-1735 MD denotes could
T19314 1725-1729 NN denotes IL-6
T19313 1717-1724 IN denotes whether
T19312 1708-1716 VBD denotes examined
T19311 1703-1707 JJ denotes next
T19310 1700-1702 PRP denotes We
T19309 1698-1699 . denotes .
T19308 1693-1698 NN denotes serum
T19307 1690-1692 NNP denotes RA
T19306 1687-1689 IN denotes in
T19305 1679-1686 JJ denotes present
T19304 1676-1678 VB denotes be
T19303 1672-1675 MD denotes may
T19302 1662-1671 VBG denotes signaling
T19301 1656-1661 CD denotes STAT1
T19300 1653-1655 IN denotes of
T19299 1642-1652 NNS denotes inhibitors
T19298 1637-1641 DT denotes that
T19297 1634-1636 CC denotes or
T19296 1632-1633 , denotes ,
T19295 1622-1632 NN denotes activation
T19294 1616-1621 CD denotes STAT3
T19293 1611-1615 IN denotes with
T19292 1602-1610 VBN denotes compared
T19291 1599-1601 IN denotes as
T19290 1588-1598 NN denotes activation
T19289 1582-1587 CD denotes STAT1
T19288 1578-1581 IN denotes for
T19287 1569-1577 VBN denotes required
T19286 1566-1568 VB denotes be
T19285 1562-1565 MD denotes may
T19284 1557-1561 NN denotes IL-6
T19283 1554-1556 IN denotes of
T19282 1539-1553 NNS denotes concentrations
T19281 1532-1538 JJR denotes higher
T19280 1527-1531 RB denotes much
T19279 1522-1526 IN denotes that
T19278 1513-1521 VBZ denotes suggests
T19277 1507-1512 NN denotes serum
T19276 1504-1506 NNP denotes RA
T19275 1501-1503 IN denotes by
T19274 1490-1500 NN denotes activation
T19273 1484-1489 CD denotes STAT1
T19272 1481-1483 IN denotes of
T19271 1476-1480 NN denotes lack
T19270 1472-1475 DT denotes The
T19269 1470-1471 . denotes .
T19268 1462-1470 NNS denotes patients
T19267 1459-1461 NNP denotes RA
T19266 1452-1458 JJ denotes active
T19265 1449-1451 IN denotes of
T19264 1444-1448 NN denotes sera
T19263 1441-1443 IN denotes in
T19262 1431-1440 VBN denotes contained
T19261 1424-1430 NN denotes factor
T19260 1407-1423 JJ denotes STAT3-activating
T19259 1398-1406 JJ denotes dominant
T19258 1394-1397 DT denotes the
T19257 1391-1393 VBZ denotes is
T19256 1386-1390 NNP denotes IL-6
T19255 1381-1385 IN denotes that
T19254 1372-1380 VBP denotes indicate
T19253 1364-1371 NNS denotes results
T19252 1358-1363 DT denotes These
T19251 1356-1357 . denotes .
T19250 1355-1356 -RRB- denotes )
T19249 1353-1355 CD denotes 5a
T19248 1348-1352 NNP denotes Fig.
T19247 1347-1348 -LRB- denotes (
T19246 1338-1346 NN denotes activity
T19245 1333-1337 NN denotes IL-6
T19244 1330-1332 IN denotes of
T19243 1315-1329 NN denotes neutralization
T19242 1312-1314 IN denotes by
T19241 1302-1311 VBN denotes abolished
T19240 1295-1301 RB denotes mostly
T19239 1291-1294 VBD denotes was
T19238 1280-1290 NN denotes activation
T19237 1274-1279 CD denotes STAT3
T19178 947-948 CD denotes 4
T19236 1269-1273 DT denotes this
T19235 1265-1268 CC denotes and
T19234 1263-1264 , denotes ,
T19233 1258-1263 NNP denotes STAT1
T19232 1254-1257 RB denotes not
T19231 1250-1253 CC denotes but
T19230 1244-1249 CD denotes STAT3
T19229 1241-1243 IN denotes of
T19228 1225-1240 NN denotes phosphorylation
T19227 1216-1224 JJ denotes tyrosine
T19226 1209-1215 VB denotes induce
T19225 1206-1208 TO denotes to
T19224 1201-1205 JJ denotes able
T19223 1197-1200 VBD denotes was
T19222 1191-1196 NN denotes serum
T19221 1188-1190 NNP denotes RA
T19220 1186-1187 . denotes .
T19219 1178-1186 NN denotes analysis
T19218 1173-1177 NN denotes blot
T19217 1165-1172 JJ denotes western
T19216 1162-1164 IN denotes by
T19215 1153-1161 VBN denotes examined
T19214 1149-1152 VBD denotes was
T19213 1133-1148 NN denotes phosphorylation
T19212 1128-1132 NNP denotes STAT
T19211 1124-1127 CC denotes and
T19210 1122-1123 , denotes ,
T19209 1114-1122 NN denotes antibody
T19208 1106-1113 NN denotes control
T19207 1103-1105 CC denotes or
T19206 1094-1102 NN denotes antibody
T19205 1084-1093 JJ denotes anti-IL-6
T19204 1071-1083 VBG denotes neutralizing
T19203 1067-1070 CC denotes and
T19202 1058-1066 NNS denotes patients
T19201 1055-1057 NNP denotes RA
T19200 1048-1054 JJ denotes active
T19199 1043-1047 IN denotes from
T19198 1037-1042 NN denotes serum
T19197 1035-1036 NN denotes %
T19196 1033-1035 CD denotes 30
T19195 1022-1032 VBG denotes containing
T19194 1015-1021 NN denotes medium
T19193 1007-1014 NN denotes culture
T19192 1002-1006 IN denotes with
T19191 998-1001 NN denotes min
T19190 995-997 CD denotes 20
T19189 991-994 IN denotes for
T19188 981-990 VBN denotes incubated
T19187 976-980 RB denotes thus
T19186 971-975 VBD denotes were
T19185 965-970 NNS denotes cells
T19184 963-964 NNP denotes T
T19183 961-962 CD denotes +
T19182 958-961 NNP denotes CD4
T19181 951-957 JJ denotes Normal
T19180 949-950 . denotes .
T19179 948-949 NNP denotes ]
T19177 946-947 VBP denotes [
T19176 933-945 NNS denotes observations
T19175 924-932 JJ denotes previous
T19174 919-923 IN denotes with
T19173 909-918 NN denotes agreement
T19172 906-908 IN denotes in
T19171 904-905 , denotes ,
T19170 903-904 -RRB- denotes )
T19169 898-903 VBN denotes shown
T19168 894-897 RB denotes not
T19167 889-893 NNS denotes data
T19166 888-889 -LRB- denotes (
T19165 882-887 NNS denotes cells
T19164 880-881 NNP denotes T
T19163 878-879 CD denotes +
T19162 875-878 NNP denotes CD4
T19161 868-874 JJ denotes normal
T19160 865-867 IN denotes in
T19159 860-864 NN denotes IL-6
T19158 857-859 IN denotes by
T19157 847-856 VBN denotes activated
T19156 843-846 VBD denotes was
T19155 827-842 NN denotes phosphorylation
T19154 821-826 CD denotes STAT3
T19153 817-820 CC denotes and
T19152 811-816 CD denotes STAT1
T19151 806-810 DT denotes Both
T19150 804-805 . denotes .
T19149 802-804 NNP denotes RA
T19148 795-801 JJ denotes active
T19147 792-794 IN denotes in
T19146 781-791 NN denotes inhibition
T19145 775-780 NNP denotes IL-10
T19144 772-774 TO denotes to
T19143 761-771 NN denotes resistance
T19142 757-760 CC denotes and
T19141 746-756 NN denotes activation
T19140 740-745 CD denotes STAT3
T19139 730-739 VBN denotes sustained
T19138 724-729 PRP$ denotes their
T19137 720-723 IN denotes for
T19136 708-719 JJ denotes responsible
T19135 704-707 VBD denotes was
T19134 692-703 NN denotes circulation
T19133 686-691 NN denotes blood
T19132 682-685 DT denotes the
T19131 679-681 IN denotes in
T19130 674-678 NN denotes IL-6
T19129 671-673 IN denotes of
T19128 656-670 NNS denotes concentrations
T19127 651-655 JJ denotes high
T19126 648-650 TO denotes to
T19125 642-647 NNS denotes cells
T19124 640-641 NNP denotes T
T19123 638-639 CD denotes +
T19122 635-638 CD denotes CD4
T19121 632-634 IN denotes of
T19120 623-631 NN denotes exposure
T19119 612-622 JJ denotes persistent
T19118 604-611 IN denotes whether
T19117 595-603 VBD denotes examined
T19116 592-594 PRP denotes we
T19115 590-591 , denotes ,
T19114 589-590 NNP denotes ]
T19113 587-589 CD denotes 27
T19112 586-587 NNP denotes [
T19111 580-585 VBN denotes ng/ml
T19110 578-579 CD denotes 1
T19109 576-577 CD denotes >
T19108 573-575 IN denotes at
T19107 564-572 VBN denotes detected
T19106 553-563 RB denotes frequently
T19105 551-552 , denotes ,
T19104 543-551 NNS denotes patients
T19103 540-542 NNP denotes RA
T19102 533-539 JJ denotes active
T19101 530-532 IN denotes of
T19100 525-529 NN denotes sera
T19099 522-524 IN denotes in
T19098 513-521 JJ denotes abundant
T19097 508-512 RB denotes also
T19096 505-507 VBZ denotes is
T19095 500-504 NNP denotes IL-6
T19094 494-499 IN denotes Since
T19093 492-493 . denotes .
T19092 491-492 NNP denotes ]
T19091 489-491 CD denotes 31
T19090 488-489 NNP denotes [
T19089 482-487 NNS denotes cells
T19088 470-481 NN denotes mononuclear
T19087 467-469 IN denotes in
T19086 461-466 CD denotes STAT3
T19085 458-460 IN denotes of
T19084 447-457 NN denotes activation
T19083 434-446 JJ denotes constitutive
T19082 426-433 VBZ denotes induces
T19081 421-425 WDT denotes that
T19080 415-420 NN denotes fluid
T19079 406-414 JJ denotes synovial
T19078 403-405 NNP denotes RA
T19077 400-402 IN denotes in
T19076 393-399 NN denotes factor
T19075 387-392 JJ denotes major
T19074 383-386 DT denotes the
T19073 380-382 VBZ denotes is
T19072 375-379 NNP denotes IL-6
T19071 370-374 IN denotes that
T19070 357-369 VBN denotes demonstrated
T19069 352-356 VBP denotes have
T19068 344-351 NNS denotes studies
T19067 335-343 JJ denotes previous
T19066 331-334 CC denotes but
T19065 329-330 , denotes ,
T19064 328-329 NNP denotes ]
T19063 327-328 CD denotes 4
T19062 326-327 NNP denotes [
T19061 320-325 NNP denotes IL-10
T19060 317-319 TO denotes to
T19059 308-316 NN denotes addition
T19058 305-307 IN denotes in
T19057 303-304 , denotes ,
T19056 297-303 NN denotes factor
T19055 290-296 NN denotes growth
T19054 280-289 JJ denotes epidermal
T19053 276-279 CC denotes and
T19052 274-275 , denotes ,
T19051 268-274 NN denotes factor
T19050 261-267 NN denotes growth
T19049 244-260 JJ denotes platelet-derived
T19048 242-243 , denotes ,
T19047 241-242 -RRB- denotes )
T19046 240-241 NNP denotes M
T19024 117-126 NNS denotes cytokines
T19023 112-116 JJ denotes many
T19022 109-111 IN denotes by
T19021 99-108 VBN denotes activated
T19020 96-98 VBZ denotes is
T19019 90-95 NNP denotes STAT3
T19018 84-89 NNS denotes cells
T19017 82-83 NNP denotes T
T19016 80-81 CD denotes +
T19015 77-80 NNP denotes CD4
T19014 70-76 JJ denotes normal
T19013 67-69 IN denotes in
T19012 60-66 NN denotes effect
T19011 54-59 JJ denotes IL-10
T19010 51-53 IN denotes of
T19009 40-50 NN denotes inhibition
T19008 36-39 CC denotes and
T19007 20-35 NN denotes phosphorylation
T19006 14-19 CD denotes STAT3
T19005 0-13 JJ denotes IL-6-mediated
T19045 229-239 NN denotes oncostatin
T19044 225-228 CC denotes and
T19043 223-224 , denotes ,
T19042 217-223 NN denotes factor
T19041 206-216 JJ denotes inhibitory
T19040 197-205 NN denotes leukemia
T19039 195-196 , denotes ,
T19038 190-195 NNP denotes IL-11
T19037 188-189 , denotes ,
T19036 184-188 NNP denotes IL-6
T19035 183-184 -LRB- denotes (
T19034 173-182 NNS denotes cytokines
T19033 170-172 IN denotes of
T19032 163-169 NN denotes family
T19031 158-162 NNP denotes IL-6
T19030 154-157 DT denotes the
T19029 151-153 IN denotes as
T19028 146-150 JJ denotes such
T19027 138-145 NNS denotes factors
T19026 131-137 NN denotes growth
T19025 127-130 CC denotes and
R9441 T19005 T19005 ROOT IL-6-mediated,IL-6-mediated
R9442 T19006 T19007 nummod STAT3,phosphorylation
R9443 T19007 T19021 nsubjpass phosphorylation,activated
R9444 T19008 T19007 cc and,phosphorylation
R9445 T19009 T19007 conj inhibition,phosphorylation
R9446 T19010 T19009 prep of,inhibition
R9447 T19011 T19012 amod IL-10,effect
R9448 T19012 T19010 pobj effect,of
R9449 T19013 T19007 prep in,phosphorylation
R9450 T19014 T19018 amod normal,cells
R9451 T19015 T19017 compound CD4,T
R9452 T19016 T19017 compound +,T
R9453 T19017 T19018 compound T,cells
R9454 T19018 T19013 pobj cells,in
R9455 T19019 T19021 nsubjpass STAT3,activated
R9456 T19020 T19021 auxpass is,activated
R9457 T19021 T19021 ROOT activated,activated
R9458 T19022 T19021 agent by,activated
R9459 T19023 T19024 amod many,cytokines
R9460 T19024 T19022 pobj cytokines,by
R9461 T19025 T19024 cc and,cytokines
R9462 T19026 T19027 compound growth,factors
R9463 T19027 T19024 conj factors,cytokines
R9464 T19028 T19029 amod such,as
R9465 T19029 T19027 prep as,factors
R9466 T19030 T19032 det the,family
R9467 T19031 T19032 compound IL-6,family
R9468 T19032 T19029 pobj family,as
R9469 T19033 T19032 prep of,family
R9470 T19034 T19033 pobj cytokines,of
R9471 T19035 T19042 punct (,factor
R9472 T19036 T19042 nmod IL-6,factor
R9473 T19037 T19036 punct ",",IL-6
R9474 T19038 T19036 conj IL-11,IL-6
R9475 T19039 T19038 punct ",",IL-11
R9476 T19040 T19042 nmod leukemia,factor
R9477 T19041 T19042 amod inhibitory,factor
R9478 T19042 T19032 appos factor,family
R9479 T19043 T19042 punct ",",factor
R9480 T19044 T19042 cc and,factor
R9481 T19045 T19046 compound oncostatin,M
R9482 T19046 T19042 conj M,factor
R9483 T19047 T19032 punct ),family
R9484 T19048 T19051 punct ",",factor
R9485 T19049 T19051 amod platelet-derived,factor
R9486 T19050 T19051 compound growth,factor
R9487 T19051 T19027 conj factor,factors
R9488 T19052 T19051 punct ",",factor
R9489 T19053 T19051 cc and,factor
R9490 T19054 T19056 amod epidermal,factor
R9491 T19055 T19056 compound growth,factor
R9492 T19056 T19051 conj factor,factor
R9493 T19057 T19051 punct ",",factor
R9494 T19058 T19070 prep in,demonstrated
R9495 T19059 T19058 pobj addition,in
R9496 T19060 T19059 prep to,addition
R9497 T19061 T19060 pobj IL-10,to
R9498 T19062 T19064 nmod [,]
R9499 T19063 T19064 nummod 4,]
R9500 T19064 T19061 dobj ],IL-10
R9501 T19065 T19061 punct ",",IL-10
R9502 T19066 T19070 cc but,demonstrated
R9503 T19067 T19068 amod previous,studies
R9504 T19068 T19070 nsubj studies,demonstrated
R9505 T19069 T19070 aux have,demonstrated
R9506 T19070 T19021 conj demonstrated,activated
R9507 T19071 T19073 mark that,is
R9508 T19072 T19073 nsubj IL-6,is
R9509 T19073 T19070 ccomp is,demonstrated
R9510 T19074 T19076 det the,factor
R9511 T19075 T19076 amod major,factor
R9512 T19076 T19073 attr factor,is
R9513 T19077 T19076 prep in,factor
R9514 T19078 T19080 nmod RA,fluid
R9515 T19079 T19080 amod synovial,fluid
R9516 T19080 T19076 appos fluid,factor
R9517 T19081 T19082 nsubj that,induces
R9518 T19082 T19080 relcl induces,fluid
R9519 T19083 T19084 amod constitutive,activation
R9520 T19084 T19082 dobj activation,induces
R9521 T19085 T19084 prep of,activation
R9522 T19086 T19085 pobj STAT3,of
R9523 T19087 T19084 prep in,activation
R9524 T19088 T19089 amod mononuclear,cells
R9525 T19089 T19087 pobj cells,in
R9526 T19090 T19092 nmod [,]
R9527 T19091 T19092 nummod 31,]
R9528 T19092 T19080 appos ],fluid
R9529 T19093 T19070 punct .,demonstrated
R9530 T19094 T19096 mark Since,is
R9531 T19095 T19096 nsubj IL-6,is
R9532 T19096 T19107 advcl is,detected
R9533 T19097 T19096 advmod also,is
R9534 T19098 T19096 acomp abundant,is
R9535 T19099 T19098 prep in,abundant
R9536 T19100 T19099 pobj sera,in
R9537 T19101 T19100 prep of,sera
R9538 T19102 T19104 amod active,patients
R9539 T19103 T19104 compound RA,patients
R9540 T19104 T19101 pobj patients,of
R9541 T19105 T19107 punct ",",detected
R9542 T19106 T19107 advmod frequently,detected
R9543 T19107 T19117 advcl detected,examined
R9544 T19108 T19107 prep at,detected
R9545 T19109 T19108 pobj >,at
R9546 T19110 T19114 nummod 1,]
R9547 T19111 T19112 amod ng/ml,[
R9548 T19112 T19114 nmod [,]
R9549 T19113 T19114 nummod 27,]
R9550 T19114 T19107 dobj ],detected
R9551 T19115 T19117 punct ",",examined
R9552 T19116 T19117 nsubj we,examined
R9553 T19117 T19117 ROOT examined,examined
R9554 T19118 T19135 mark whether,was
R9555 T19119 T19120 amod persistent,exposure
R9556 T19120 T19135 nsubj exposure,was
R9557 T19121 T19120 prep of,exposure
R9558 T19122 T19125 nummod CD4,cells
R9559 T19123 T19125 nummod +,cells
R9560 T19124 T19125 compound T,cells
R9561 T19125 T19121 pobj cells,of
R9562 T19126 T19120 prep to,exposure
R9563 T19127 T19128 amod high,concentrations
R9564 T19128 T19126 pobj concentrations,to
R9565 T19129 T19128 prep of,concentrations
R9566 T19130 T19129 pobj IL-6,of
R9567 T19131 T19128 prep in,concentrations
R9568 T19132 T19134 det the,circulation
R9569 T19133 T19134 compound blood,circulation
R9570 T19134 T19131 pobj circulation,in
R9571 T19135 T19117 ccomp was,examined
R9572 T19136 T19135 acomp responsible,was
R9573 T19137 T19136 prep for,responsible
R9574 T19138 T19141 poss their,activation
R9575 T19139 T19141 amod sustained,activation
R9576 T19140 T19141 nummod STAT3,activation
R9577 T19141 T19137 pobj activation,for
R9578 T19142 T19141 cc and,activation
R9579 T19143 T19141 conj resistance,activation
R9580 T19144 T19143 prep to,resistance
R9581 T19145 T19146 compound IL-10,inhibition
R9582 T19146 T19144 pobj inhibition,to
R9583 T19147 T19146 prep in,inhibition
R9584 T19148 T19149 amod active,RA
R9585 T19149 T19147 pobj RA,in
R9586 T19150 T19117 punct .,examined
R9587 T19151 T19152 det Both,STAT1
R9588 T19152 T19155 nummod STAT1,phosphorylation
R9589 T19153 T19152 cc and,STAT1
R9590 T19154 T19152 conj STAT3,STAT1
R9591 T19155 T19157 nsubjpass phosphorylation,activated
R9592 T19156 T19157 auxpass was,activated
R9593 T19157 T19157 ROOT activated,activated
R9594 T19158 T19157 agent by,activated
R9595 T19159 T19158 pobj IL-6,by
R9596 T19160 T19157 prep in,activated
R9597 T19161 T19165 amod normal,cells
R9598 T19162 T19165 nmod CD4,cells
R9599 T19163 T19165 nummod +,cells
R9600 T19164 T19165 compound T,cells
R9601 T19165 T19160 pobj cells,in
R9602 T19166 T19165 punct (,cells
R9603 T19167 T19177 nsubj data,[
R9604 T19168 T19169 neg not,shown
R9605 T19169 T19167 acl shown,data
R9606 T19170 T19167 punct ),data
R9607 T19171 T19177 punct ",",[
R9608 T19172 T19177 prep in,[
R9609 T19173 T19172 pobj agreement,in
R9610 T19174 T19173 prep with,agreement
R9611 T19175 T19176 amod previous,observations
R9612 T19176 T19174 pobj observations,with
R9613 T19177 T19157 advcl [,activated
R9614 T19178 T19179 nummod 4,]
R9615 T19179 T19177 dobj ],[
R9616 T19180 T19177 punct .,[
R9617 T19181 T19185 amod Normal,cells
R9618 T19182 T19185 compound CD4,cells
R9619 T19183 T19185 nummod +,cells
R9620 T19184 T19185 compound T,cells
R9621 T19185 T19188 nsubjpass cells,incubated
R9622 T19186 T19188 auxpass were,incubated
R9623 T19187 T19188 advmod thus,incubated
R9624 T19188 T19188 ROOT incubated,incubated
R9625 T19189 T19188 prep for,incubated
R9626 T19190 T19191 nummod 20,min
R9627 T19191 T19189 pobj min,for
R9628 T19192 T19191 prep with,min
R9629 T19193 T19194 compound culture,medium
R9630 T19194 T19195 nsubj medium,containing
R9631 T19195 T19192 pcomp containing,with
R9632 T19196 T19197 nummod 30,%
R9633 T19197 T19198 compound %,serum
R9634 T19198 T19195 dobj serum,containing
R9635 T19199 T19198 prep from,serum
R9636 T19200 T19202 amod active,patients
R9637 T19201 T19202 compound RA,patients
R9638 T19202 T19199 pobj patients,from
R9639 T19203 T19195 cc and,containing
R9640 T19204 T19195 conj neutralizing,containing
R9641 T19205 T19206 amod anti-IL-6,antibody
R9642 T19206 T19204 dobj antibody,neutralizing
R9643 T19207 T19206 cc or,antibody
R9644 T19208 T19209 compound control,antibody
R9645 T19209 T19206 conj antibody,antibody
R9646 T19210 T19204 punct ",",neutralizing
R9647 T19211 T19204 cc and,neutralizing
R9648 T19212 T19213 compound STAT,phosphorylation
R9649 T19213 T19215 nsubjpass phosphorylation,examined
R9650 T19214 T19215 auxpass was,examined
R9651 T19215 T19188 advcl examined,incubated
R9652 T19216 T19215 agent by,examined
R9653 T19217 T19219 amod western,analysis
R9654 T19218 T19219 compound blot,analysis
R9655 T19219 T19216 pobj analysis,by
R9656 T19220 T19215 punct .,examined
R9657 T19221 T19222 compound RA,serum
R9658 T19222 T19223 nsubj serum,was
R9659 T19223 T19223 ROOT was,was
R9660 T19224 T19223 acomp able,was
R9661 T19225 T19226 aux to,induce
R9662 T19226 T19224 xcomp induce,able
R9663 T19227 T19228 amod tyrosine,phosphorylation
R9664 T19228 T19226 dobj phosphorylation,induce
R9665 T19229 T19228 prep of,phosphorylation
R9666 T19230 T19229 pobj STAT3,of
R9667 T19231 T19230 cc but,STAT3
R9668 T19232 T19233 neg not,STAT1
R9669 T19233 T19241 nsubjpass STAT1,abolished
R9670 T19234 T19233 punct ",",STAT1
R9671 T19235 T19233 cc and,STAT1
R9672 T19236 T19238 det this,activation
R9673 T19237 T19238 nummod STAT3,activation
R9674 T19238 T19233 conj activation,STAT1
R9675 T19239 T19241 auxpass was,abolished
R9676 T19240 T19241 advmod mostly,abolished
R9677 T19241 T19223 advcl abolished,was
R9678 T19242 T19241 agent by,abolished
R9679 T19243 T19242 pobj neutralization,by
R9680 T19244 T19243 prep of,neutralization
R9681 T19245 T19246 compound IL-6,activity
R9682 T19246 T19244 pobj activity,of
R9683 T19247 T19241 punct (,abolished
R9684 T19248 T19249 compound Fig.,5a
R9685 T19249 T19241 npadvmod 5a,abolished
R9686 T19250 T19241 punct ),abolished
R9687 T19251 T19223 punct .,was
R9688 T19252 T19253 det These,results
R9689 T19253 T19254 nsubj results,indicate
R9690 T19254 T19254 ROOT indicate,indicate
R9691 T19255 T19257 mark that,is
R9692 T19256 T19257 nsubj IL-6,is
R9693 T19257 T19254 ccomp is,indicate
R9694 T19258 T19261 det the,factor
R9695 T19259 T19261 amod dominant,factor
R9696 T19260 T19261 amod STAT3-activating,factor
R9697 T19261 T19257 attr factor,is
R9698 T19262 T19261 acl contained,factor
R9699 T19263 T19262 prep in,contained
R9700 T19264 T19263 pobj sera,in
R9701 T19265 T19264 prep of,sera
R9702 T19266 T19268 amod active,patients
R9703 T19267 T19268 compound RA,patients
R9704 T19268 T19265 pobj patients,of
R9705 T19269 T19254 punct .,indicate
R9706 T19270 T19271 det The,lack
R9707 T19271 T19278 nsubj lack,suggests
R9708 T19272 T19271 prep of,lack
R9709 T19273 T19274 nummod STAT1,activation
R9710 T19274 T19272 pobj activation,of
R9711 T19275 T19274 prep by,activation
R9712 T19276 T19277 compound RA,serum
R9713 T19277 T19275 pobj serum,by
R9714 T19278 T19278 ROOT suggests,suggests
R9715 T19279 T19287 mark that,required
R9716 T19280 T19281 advmod much,higher
R9717 T19281 T19282 amod higher,concentrations
R9718 T19282 T19287 nsubjpass concentrations,required
R9719 T19283 T19282 prep of,concentrations
R9720 T19284 T19283 pobj IL-6,of
R9721 T19285 T19287 aux may,required
R9722 T19286 T19287 auxpass be,required
R9723 T19287 T19278 ccomp required,suggests
R9724 T19288 T19287 prep for,required
R9725 T19289 T19290 nummod STAT1,activation
R9726 T19290 T19288 pobj activation,for
R9727 T19291 T19290 prep as,activation
R9728 T19292 T19291 prep compared,as
R9729 T19293 T19292 prep with,compared
R9730 T19294 T19295 nummod STAT3,activation
R9731 T19295 T19293 pobj activation,with
R9732 T19296 T19295 punct ",",activation
R9733 T19297 T19295 cc or,activation
R9734 T19298 T19304 mark that,be
R9735 T19299 T19304 nsubj inhibitors,be
R9736 T19300 T19299 prep of,inhibitors
R9737 T19301 T19300 pobj STAT1,of
R9738 T19302 T19304 nsubj signaling,be
R9739 T19303 T19304 aux may,be
R9740 T19304 T19287 advcl be,required
R9741 T19305 T19304 acomp present,be
R9742 T19306 T19305 prep in,present
R9743 T19307 T19308 compound RA,serum
R9744 T19308 T19306 pobj serum,in
R9745 T19309 T19278 punct .,suggests
R9746 T19310 T19312 nsubj We,examined
R9747 T19311 T19312 advmod next,examined
R9748 T19312 T19312 ROOT examined,examined
R9749 T19313 T19316 mark whether,suppress
R9750 T19314 T19316 nsubj IL-6,suppress
R9751 T19315 T19316 aux could,suppress
R9752 T19316 T19312 ccomp suppress,examined
R9753 T19317 T19318 det the,effect
R9754 T19318 T19316 dobj effect,suppress
R9755 T19319 T19318 prep of,effect
R9756 T19320 T19319 pobj IL-10,of
R9757 T19321 T19322 aux to,inhibit
R9758 T19322 T19316 advcl inhibit,suppress
R9759 T19323 T19324 amod IFN-γ,production
R9760 T19324 T19322 dobj production,inhibit
R9761 T19325 T19324 prep by,production
R9762 T19326 T19329 compound CD4,cells
R9763 T19327 T19329 compound +,cells
R9764 T19328 T19329 compound T,cells
R9765 T19329 T19325 pobj cells,by
R9766 T19330 T19312 punct .,examined
R9767 T19331 T19349 prep After,stimulated
R9768 T19332 T19331 pobj preincubation,After
R9769 T19333 T19332 prep with,preincubation
R9770 T19334 T19333 cc or,with
R9771 T19335 T19333 conj without,with
R9772 T19336 T19337 nummod 10,ng/ml
R9773 T19337 T19338 compound ng/ml,IL-6
R9774 T19338 T19335 pobj IL-6,without
R9775 T19339 T19332 prep for,preincubation
R9776 T19340 T19341 nummod 36,hours
R9777 T19341 T19339 pobj hours,for
R9778 T19342 T19349 punct ",",stimulated
R9779 T19343 T19347 amod normal,cells
R9780 T19344 T19347 compound CD4,cells
R9781 T19345 T19347 nummod +,cells
R9782 T19346 T19347 compound T,cells
R9783 T19347 T19349 nsubjpass cells,stimulated
R9784 T19348 T19349 auxpass were,stimulated
R9785 T19349 T19349 ROOT stimulated,stimulated
R9786 T19350 T19349 agent by,stimulated
R9787 T19351 T19350 pobj CD3,by
R9788 T19352 T19351 cc and,CD3
R9789 T19353 T19354 compound CD28,costimulation
R9790 T19354 T19351 conj costimulation,CD3
R9791 T19355 T19354 prep in,costimulation
R9792 T19356 T19357 det the,presence
R9793 T19357 T19355 pobj presence,in
R9794 T19358 T19357 cc or,presence
R9795 T19359 T19357 conj absence,presence
R9796 T19360 T19357 prep of,presence
R9797 T19361 T19362 nummod 1,ng/ml
R9798 T19362 T19363 compound ng/ml,IL-10
R9799 T19363 T19360 pobj IL-10,of
R9800 T19364 T19354 prep for,costimulation
R9801 T19365 T19366 nummod 36,hours
R9802 T19366 T19364 pobj hours,for
R9803 T19367 T19354 punct ",",costimulation
R9804 T19368 T19354 cc and,costimulation
R9805 T19369 T19371 det the,production
R9806 T19370 T19371 compound IFN-γ,production
R9807 T19371 T19373 nsubjpass production,measured
R9808 T19372 T19373 auxpass was,measured
R9809 T19373 T19349 conj measured,stimulated
R9810 T19374 T19373 agent by,measured
R9811 T19375 T19374 pobj ELISA,by
R9812 T19376 T19373 punct .,measured
R9813 T19377 T19378 compound IL-6,pretreatment
R9814 T19378 T19382 nsubj pretreatment,reduced
R9815 T19379 T19378 prep of,pretreatment
R9816 T19380 T19381 amod normal,cells
R9817 T19381 T19379 pobj cells,of
R9818 T19382 T19382 ROOT reduced,reduced
R9819 T19383 T19384 amod IL-10-mediated,inhibition
R9820 T19384 T19382 dobj inhibition,reduced
R9821 T19385 T19384 prep of,inhibition
R9822 T19386 T19387 compound IFN-γ,production
R9823 T19387 T19385 pobj production,of
R9824 T19388 T19387 punct (,production
R9825 T19389 T19384 appos Fig.,inhibition
R9826 T19390 T19389 nummod 5b,Fig.
R9827 T19391 T19382 punct ),reduced
R9828 T19392 T19382 punct ",",reduced
R9829 T19393 T19382 advcl indicating,reduced
R9830 T19394 T19400 mark that,modulate
R9831 T19395 T19396 amod high,concentrations
R9832 T19396 T19400 nsubj concentrations,modulate
R9833 T19397 T19396 prep of,concentrations
R9834 T19398 T19397 pobj IL-6,of
R9835 T19399 T19400 aux could,modulate
R9836 T19400 T19393 ccomp modulate,indicating
R9837 T19401 T19402 compound T-cell,responsiveness
R9838 T19402 T19400 dobj responsiveness,modulate
R9839 T19403 T19402 prep to,responsiveness
R9840 T19404 T19403 pobj IL-10,to
R9841 T19405 T19382 punct .,reduced
R9842 T19406 T19411 advcl Taken,suggest
R9843 T19407 T19406 advmod together,Taken
R9844 T19408 T19411 punct ",",suggest
R9845 T19409 T19410 det these,findings
R9846 T19410 T19411 nsubj findings,suggest
R9847 T19411 T19411 ROOT suggest,suggest
R9848 T19412 T19419 mark that,have
R9849 T19413 T19414 amod persistent,exposure
R9850 T19414 T19419 nsubj exposure,have
R9851 T19415 T19416 aux to,serum
R9852 T19416 T19414 acl serum,exposure
R9853 T19417 T19416 dobj IL-6,serum
R9854 T19418 T19419 aux may,have
R9855 T19419 T19411 ccomp have,suggest
R9856 T19420 T19421 det a,role
R9857 T19421 T19419 dobj role,have
R9858 T19422 T19421 prep in,role
R9859 T19423 T19425 preconj both,induction
R9860 T19424 T19425 det the,induction
R9861 T19425 T19422 pobj induction,in
R9862 T19426 T19425 prep of,induction
R9863 T19427 T19428 nummod STAT3,activation
R9864 T19428 T19426 pobj activation,of
R9865 T19429 T19428 cc and,activation
R9866 T19430 T19431 det the,resistance
R9867 T19431 T19428 conj resistance,activation
R9868 T19432 T19431 prep to,resistance
R9869 T19433 T19435 det the,effect
R9870 T19434 T19435 amod inhibitory,effect
R9871 T19435 T19432 pobj effect,to
R9872 T19436 T19435 prep of,effect
R9873 T19437 T19436 pobj IL-10,of
R9874 T19438 T19435 prep in,effect
R9875 T19439 T19440 compound RA,CD4
R9876 T19440 T19438 pobj CD4,in
R9877 T19441 T19443 amod +,cells
R9878 T19442 T19443 compound T,cells
R9879 T19443 T19425 conj cells,induction
R9880 T19444 T19411 punct .,suggest

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T18391 2428-2434 Protein denotes RA CD4
T18390 2419-2424 Protein denotes IL-10
T18389 2355-2360 Protein denotes STAT3
T18388 2303-2313 Protein denotes serum IL-6
T18387 2080-2087 Negative_regulation denotes reduced
T18386 2103-2113 Negative_regulation denotes inhibition
T18385 2123-2133 Gene_expression denotes production
T18384 2229-2234 Protein denotes IL-10
T18383 2184-2188 Protein denotes IL-6
T18382 2117-2122 Protein denotes IFN-γ
T18381 2088-2093 Protein denotes IL-10
T18380 2012-2022 Gene_expression denotes production
T18352 1209-1215 Positive_regulation denotes induce
T18351 1209-1215 Positive_regulation denotes induce
T18350 1315-1329 Negative_regulation denotes neutralization
T18349 1315-1329 Negative_regulation denotes neutralization
T18348 1280-1290 Positive_regulation denotes activation
T18347 1225-1240 Phosphorylation denotes phosphorylation
T18346 1225-1240 Phosphorylation denotes phosphorylation
T18345 1216-1224 Entity denotes tyrosine
T18344 1348-1355 Protein denotes Fig. 5a
T18343 1333-1337 Protein denotes IL-6
T18342 1274-1279 Protein denotes STAT3
T18341 1258-1263 Protein denotes STAT1
T18340 1244-1249 Protein denotes STAT3
T18339 1133-1148 Phosphorylation denotes phosphorylation
T18338 1071-1083 Positive_regulation denotes neutralizing
T18337 1128-1132 Protein denotes STAT
T18336 1084-1122 Protein denotes anti-IL-6 antibody or control antibody
T18335 958-961 Protein denotes CD4
T18334 847-856 Positive_regulation denotes activated
T18333 847-856 Positive_regulation denotes activated
T18332 847-856 Positive_regulation denotes activated
T18331 847-856 Positive_regulation denotes activated
T18330 827-842 Phosphorylation denotes phosphorylation
T18329 827-842 Phosphorylation denotes phosphorylation
T18328 875-879 Protein denotes CD4+
T18327 860-864 Protein denotes IL-6
T18326 821-826 Protein denotes STAT3
T18325 811-816 Protein denotes STAT1
T18324 708-719 Positive_regulation denotes responsible
T18323 781-791 Negative_regulation denotes inhibition
T18322 746-756 Positive_regulation denotes activation
T18321 656-670 Positive_regulation denotes concentrations
T18320 775-780 Protein denotes IL-10
T18319 740-745 Protein denotes STAT3
T18318 674-678 Protein denotes IL-6
T18317 635-639 Protein denotes CD4+
T18316 500-504 Protein denotes IL-6
T18315 426-433 Positive_regulation denotes induces
T18314 447-457 Positive_regulation denotes activation
T18313 99-108 Positive_regulation denotes activated
T18312 461-466 Protein denotes STAT3
T18311 375-379 Protein denotes IL-6
T18310 229-241 Protein denotes oncostatin M
T18309 190-195 Protein denotes IL-11
T18308 90-95 Protein denotes STAT3
T18307 40-50 Negative_regulation denotes inhibition
T18306 5-13 Positive_regulation denotes mediated
T18305 60-66 Regulation denotes effect
T18304 20-35 Phosphorylation denotes phosphorylation
T18303 77-81 Protein denotes CD4+
T18302 54-59 Protein denotes IL-10
T18301 14-19 Protein denotes STAT3
T18300 0-4 Protein denotes IL-6
T18379 2006-2011 Protein denotes IFN-γ
T18378 1921-1925 Protein denotes CD28
T18377 1913-1916 Protein denotes CD3
T18376 1881-1885 Protein denotes CD4+
T18375 1768-1775 Negative_regulation denotes inhibit
T18374 1782-1792 Gene_expression denotes production
T18373 1796-1800 Protein denotes CD4+
T18372 1776-1781 Protein denotes IFN-γ
T18371 1759-1764 Protein denotes IL-10
T18370 1725-1729 Protein denotes IL-6
T18369 1569-1577 Positive_regulation denotes required
T18368 1476-1480 Negative_regulation denotes lack
T18367 1679-1686 Positive_regulation denotes present
T18366 1642-1652 Negative_regulation denotes inhibitors
T18365 1622-1632 Positive_regulation denotes activation
T18364 1588-1598 Positive_regulation denotes activation
T18363 1539-1553 Positive_regulation denotes concentrations
T18362 1490-1500 Positive_regulation denotes activation
T18361 1656-1661 Protein denotes STAT1
T18360 1616-1621 Protein denotes STAT3
T18359 1582-1587 Protein denotes STAT1
T18358 1557-1561 Protein denotes IL-6
T18357 1484-1489 Protein denotes STAT1
T18356 1398-1430 Protein denotes dominant STAT3-activating factor
T18355 1386-1390 Protein denotes IL-6
T18354 1302-1311 Negative_regulation denotes abolished
T18353 1302-1311 Negative_regulation denotes abolished
R8948 T18357 T18362 themeOf STAT1,activation
R8949 T18358 T18363 themeOf IL-6,concentrations
R8950 T18359 T18364 themeOf STAT1,activation
R8951 T18360 T18365 themeOf STAT3,activation
R8952 T18361 T18366 themeOf STAT1,inhibitors
R8953 T18362 T18368 themeOf activation,lack
R8954 T18364 T18369 themeOf activation,required
R8955 T18366 T18367 themeOf inhibitors,present
R8956 T18371 T18375 causeOf IL-10,inhibit
R8957 T18372 T18374 themeOf IFN-γ,production
R8958 T18374 T18375 themeOf production,inhibit
R8959 T18379 T18380 themeOf IFN-γ,production
R8960 T18381 T18386 causeOf IL-10,inhibition
R8961 T18382 T18385 themeOf IFN-γ,production
R8962 T18385 T18386 themeOf production,inhibition
R8963 T18386 T18387 themeOf inhibition,reduced
R8909 T18300 T18306 causeOf IL-6,mediated
R8910 T18301 T18304 themeOf STAT3,phosphorylation
R8911 T18302 T18305 themeOf IL-10,effect
R8912 T18304 T18306 themeOf phosphorylation,mediated
R8913 T18305 T18307 themeOf effect,inhibition
R8914 T18308 T18313 themeOf STAT3,activated
R8915 T18312 T18314 themeOf STAT3,activation
R8916 T18314 T18315 themeOf activation,induces
R8917 T18318 T18321 themeOf IL-6,concentrations
R8918 T18319 T18322 themeOf STAT3,activation
R8919 T18320 T18323 themeOf IL-10,inhibition
R8920 T18322 T18324 themeOf activation,responsible
R8921 T18325 T18329 themeOf STAT1,phosphorylation
R8923 T18326 T18330 themeOf STAT3,phosphorylation
R8925 T18327 T18331 causeOf IL-6,activated
R8922 T18325 T18331 themeOf STAT1,activated
R8924 T18326 T18332 themeOf STAT3,activated
R8926 T18327 T18332 causeOf IL-6,activated
R8927 T18327 T18333 causeOf IL-6,activated
R8928 T18327 T18334 causeOf IL-6,activated
R8929 T18329 T18333 themeOf phosphorylation,activated
R8930 T18330 T18334 themeOf phosphorylation,activated
R8931 T18336 T18338 themeOf anti-IL-6 antibody or control antibody,neutralizing
R8932 T18337 T18339 themeOf STAT,phosphorylation
R8933 T18340 T18346 themeOf STAT3,phosphorylation
R8934 T18340 T18345 partOf STAT3,tyrosine
R8935 T18341 T18347 themeOf STAT1,phosphorylation
R8936 T18341 T18345 partOf STAT1,tyrosine
R8937 T18342 T18348 themeOf STAT3,activation
R8938 T18343 T18349 themeOf IL-6,neutralization
R8939 T18344 T18350 themeOf Fig. 5a,neutralization
R8940 T18345 T18346 Site tyrosine,phosphorylation
R8941 T18345 T18347 Site tyrosine,phosphorylation
R8942 T18346 T18351 themeOf phosphorylation,induce
R8943 T18347 T18352 themeOf phosphorylation,induce
R8944 T18348 T18353 themeOf activation,abolished
R8945 T18348 T18354 themeOf activation,abolished
R8946 T18349 T18353 causeOf neutralization,abolished
R8947 T18350 T18354 causeOf neutralization,abolished

test3

Id Subject Object Predicate Lexical cue
T17456 2431-2434 Protein denotes CD4
T17455 2419-2424 Protein denotes IL-10
T17454 2409-2415 Regulation denotes effect
T17453 2361-2371 Positive_regulation denotes activation
T17452 2355-2360 Protein denotes STAT3
T17451 2342-2351 Positive_regulation denotes induction
T17450 2325-2329 Regulation denotes role
T17449 2309-2313 Protein denotes IL-6
T17448 2229-2234 Protein denotes IL-10
T17447 2184-2188 Protein denotes IL-6
T17446 2123-2133 Gene_expression denotes production
T17445 2117-2122 Protein denotes IFN-γ
T17444 2103-2113 Negative_regulation denotes inhibition
T17443 2094-2102 Positive_regulation denotes mediated
T17442 2088-2093 Protein denotes IL-10
T17441 2080-2087 Negative_regulation denotes reduced
T17440 2046-2050 Protein denotes IL-6
T17439 2012-2022 Gene_expression denotes production
T17438 2006-2011 Protein denotes IFN-γ
T17437 1978-1983 Protein denotes IL-10
T17436 1959-1966 Negative_regulation denotes absence
T17435 1921-1925 Protein denotes CD28
T17434 1881-1884 Protein denotes CD4
T17433 1855-1859 Protein denotes IL-6
T17432 1796-1799 Protein denotes CD4
T17431 1782-1792 Gene_expression denotes production
T17430 1776-1781 Protein denotes IFN-γ
T17429 1768-1775 Negative_regulation denotes inhibit
T17428 1759-1764 Protein denotes IL-10
T17427 1749-1755 Regulation denotes effect
T17426 1736-1744 Negative_regulation denotes suppress
T17425 1725-1729 Protein denotes IL-6
T17424 1656-1661 Protein denotes STAT1
T17423 1642-1652 Negative_regulation denotes inhibitors
T17422 1622-1632 Positive_regulation denotes activation
T17421 1616-1621 Protein denotes STAT3
T17420 1588-1598 Positive_regulation denotes activation
T17419 1582-1587 Protein denotes STAT1
T17418 1569-1577 Positive_regulation denotes required
T17417 1557-1561 Protein denotes IL-6
T17416 1490-1500 Positive_regulation denotes activation
T17415 1484-1489 Protein denotes STAT1
T17414 1476-1480 Negative_regulation denotes lack
T17413 1407-1412 Protein denotes STAT3
T17412 1386-1390 Protein denotes IL-6
T17411 1333-1337 Protein denotes IL-6
T17410 1315-1329 Negative_regulation denotes neutralization
T17409 1302-1311 Negative_regulation denotes abolished
T17408 1280-1290 Positive_regulation denotes activation
T17407 1274-1279 Protein denotes STAT3
T17406 1258-1263 Protein denotes STAT1
T17405 1244-1249 Protein denotes STAT3
T17404 1225-1240 Phosphorylation denotes phosphorylation
T17403 1209-1215 Positive_regulation denotes induce
T17402 1133-1148 Phosphorylation denotes phosphorylation
T17401 1089-1093 Protein denotes IL-6
T17400 958-961 Protein denotes CD4
T17399 875-878 Protein denotes CD4
T17398 860-864 Protein denotes IL-6
T17397 847-856 Positive_regulation denotes activated
T17396 827-842 Phosphorylation denotes phosphorylation
T17395 821-826 Protein denotes STAT3
T17394 811-816 Protein denotes STAT1
T17393 781-791 Negative_regulation denotes inhibition
T17392 775-780 Protein denotes IL-10
T17391 746-756 Positive_regulation denotes activation
T17390 740-745 Protein denotes STAT3
T17389 674-678 Protein denotes IL-6
T17388 635-638 Protein denotes CD4
T17387 500-504 Protein denotes IL-6
T17386 461-466 Protein denotes STAT3
T17385 447-457 Positive_regulation denotes activation
T17384 426-433 Positive_regulation denotes induces
T17383 375-379 Protein denotes IL-6
T17382 320-325 Protein denotes IL-10
T17381 280-303 Protein denotes epidermal growth factor
T17380 244-274 Protein denotes platelet-derived growth factor
T17379 229-241 Protein denotes oncostatin M
T17378 197-223 Protein denotes leukemia inhibitory factor
T17377 190-195 Protein denotes IL-11
T17376 184-188 Protein denotes IL-6
T17375 99-108 Positive_regulation denotes activated
T17374 90-95 Protein denotes STAT3
T17373 77-80 Protein denotes CD4
T17372 60-66 Regulation denotes effect
T17371 54-59 Protein denotes IL-10
T17370 40-50 Negative_regulation denotes inhibition
T17369 20-35 Phosphorylation denotes phosphorylation
T17368 14-19 Protein denotes STAT3
T17367 5-13 Positive_regulation denotes mediated
T17366 0-4 Protein denotes IL-6
T17365 2431-2434 Protein denotes CD4
T17364 2419-2424 Protein denotes IL-10
T17363 2355-2360 Protein denotes STAT3
T17362 2309-2313 Protein denotes IL-6
T17361 2229-2234 Protein denotes IL-10
T17360 2184-2188 Protein denotes IL-6
T17359 2117-2122 Protein denotes IFN-γ
T17358 2088-2093 Protein denotes IL-10
T17357 2046-2050 Protein denotes IL-6
T17356 2006-2011 Protein denotes IFN-γ
T17355 1978-1983 Protein denotes IL-10
T17354 1921-1925 Protein denotes CD28
T17353 1881-1884 Protein denotes CD4
T17352 1855-1859 Protein denotes IL-6
T17351 1796-1799 Protein denotes CD4
T17350 1776-1781 Protein denotes IFN-γ
T17349 1759-1764 Protein denotes IL-10
T17348 1725-1729 Protein denotes IL-6
T17347 1656-1661 Protein denotes STAT1
T17346 1616-1621 Protein denotes STAT3
T17345 1582-1587 Protein denotes STAT1
T17344 1557-1561 Protein denotes IL-6
T17343 1484-1489 Protein denotes STAT1
T17342 1407-1412 Protein denotes STAT3
T17341 1386-1390 Protein denotes IL-6
T17340 1333-1337 Protein denotes IL-6
T17339 1274-1279 Protein denotes STAT3
T17338 1258-1263 Protein denotes STAT1
T17337 1244-1249 Protein denotes STAT3
T17336 1089-1093 Protein denotes IL-6
T17335 958-961 Protein denotes CD4
T17334 875-878 Protein denotes CD4
T17333 860-864 Protein denotes IL-6
T17332 821-826 Protein denotes STAT3
T17331 811-816 Protein denotes STAT1
T17330 775-780 Protein denotes IL-10
T17329 740-745 Protein denotes STAT3
T17328 674-678 Protein denotes IL-6
T17327 635-638 Protein denotes CD4
T17326 500-504 Protein denotes IL-6
T17325 461-466 Protein denotes STAT3
T17324 375-379 Protein denotes IL-6
T17323 320-325 Protein denotes IL-10
T17322 280-303 Protein denotes epidermal growth factor
T17321 244-274 Protein denotes platelet-derived growth factor
T17320 229-241 Protein denotes oncostatin M
T17319 197-223 Protein denotes leukemia inhibitory factor
T17318 190-195 Protein denotes IL-11
T17317 184-188 Protein denotes IL-6
T17316 90-95 Protein denotes STAT3
T17315 77-80 Protein denotes CD4
T17314 54-59 Protein denotes IL-10
T17313 14-19 Protein denotes STAT3
T17312 0-4 Protein denotes IL-6
R8776 T17366 T17367 causeOf IL-6,mediated
R8777 T17368 T17369 themeOf STAT3,phosphorylation
R8778 T17369 T17367 themeOf phosphorylation,mediated
R8779 T17370 T17372 themeOf inhibition,effect
R8780 T17371 T17370 themeOf IL-10,inhibition
R8781 T17374 T17375 themeOf STAT3,activated
R8782 T17377 T17375 causeOf IL-11,activated
R8783 T17378 T17375 causeOf leukemia inhibitory factor,activated
R8784 T17379 T17375 causeOf oncostatin M,activated
R8785 T17379 T17384 causeOf oncostatin M,induces
R8786 T17380 T17375 causeOf platelet-derived growth factor,activated
R8787 T17381 T17384 causeOf epidermal growth factor,induces
R8788 T17381 T17375 causeOf epidermal growth factor,activated
R8789 T17382 T17375 causeOf IL-10,activated
R8790 T17383 T17384 causeOf IL-6,induces
R8791 T17385 T17384 themeOf activation,induces
R8792 T17386 T17385 themeOf STAT3,activation
R8793 T17390 T17391 themeOf STAT3,activation
R8794 T17392 T17393 themeOf IL-10,inhibition
R8795 T17394 T17396 themeOf STAT1,phosphorylation
R8796 T17395 T17396 themeOf STAT3,phosphorylation
R8797 T17396 T17397 themeOf phosphorylation,activated
R8798 T17398 T17397 causeOf IL-6,activated
R8799 T17403 T17409 themeOf induce,abolished
R8800 T17404 T17403 themeOf phosphorylation,induce
R8801 T17404 T17409 themeOf phosphorylation,abolished
R8802 T17405 T17404 themeOf STAT3,phosphorylation
R8803 T17406 T17404 themeOf STAT1,phosphorylation
R8804 T17407 T17408 themeOf STAT3,activation
R8805 T17408 T17409 themeOf activation,abolished
R8806 T17410 T17409 causeOf neutralization,abolished
R8807 T17411 T17410 themeOf IL-6,neutralization
R8808 T17415 T17416 themeOf STAT1,activation
R8809 T17416 T17414 themeOf activation,lack
R8810 T17419 T17420 themeOf STAT1,activation
R8811 T17420 T17418 themeOf activation,required
R8812 T17421 T17422 themeOf STAT3,activation
R8813 T17422 T17418 themeOf activation,required
R8814 T17425 T17429 causeOf IL-6,inhibit
R8815 T17425 T17426 causeOf IL-6,suppress
R8816 T17428 T17427 causeOf IL-10,effect
R8817 T17430 T17431 themeOf IFN-γ,production
R8818 T17431 T17429 themeOf production,inhibit
R8819 T17438 T17439 themeOf IFN-γ,production
R8820 T17442 T17444 causeOf IL-10,inhibition
R8821 T17442 T17443 causeOf IL-10,mediated
R8822 T17443 T17441 themeOf mediated,reduced
R8823 T17445 T17446 themeOf IFN-γ,production
R8824 T17446 T17444 themeOf production,inhibition
R8825 T17449 T17450 causeOf IL-6,role
R8826 T17452 T17453 themeOf STAT3,activation
R8827 T17453 T17451 themeOf activation,induction

testone

Id Subject Object Predicate Lexical cue
T17264 2398-2415 Negative_regulation denotes inhibitory effect
T17263 2361-2371 Positive_regulation denotes activation
T17262 2342-2351 Positive_regulation denotes induction
T17261 2325-2329 Regulation denotes role
T17260 2123-2133 Gene_expression denotes production
T17259 2103-2113 Negative_regulation denotes inhibition
T17258 2094-2102 Positive_regulation denotes mediated
T17257 2080-2087 Negative_regulation denotes reduced
T17256 2012-2022 Gene_expression denotes production
T17255 1768-1775 Negative_regulation denotes inhibit
T17254 1749-1755 Regulation denotes effect
T17253 1736-1744 Negative_regulation denotes suppress
T17252 1622-1632 Positive_regulation denotes activation
T17251 1569-1577 Positive_regulation denotes required
T17250 1315-1329 Negative_regulation denotes neutralization
T17249 1302-1311 Negative_regulation denotes abolished
T17248 1280-1290 Positive_regulation denotes activation
T17247 1225-1240 Phosphorylation denotes phosphorylation
T17246 1209-1215 Positive_regulation denotes induce
T17245 1133-1148 Phosphorylation denotes phosphorylation
T17244 847-856 Positive_regulation denotes activated
T17243 827-842 Phosphorylation denotes phosphorylation
T17242 781-791 Negative_regulation denotes inhibition
T17241 746-756 Positive_regulation denotes activation
T17240 708-719 Positive_regulation denotes responsible
T17239 447-457 Positive_regulation denotes activation
T17238 426-433 Positive_regulation denotes induces
T17237 99-108 Positive_regulation denotes activated
T17236 60-66 Regulation denotes effect
T17235 40-50 Negative_regulation denotes inhibition
T17234 20-35 Phosphorylation denotes phosphorylation
T17233 5-13 Positive_regulation denotes mediated
T17232 2431-2434 Protein denotes CD4
T17231 2419-2424 Protein denotes IL-10
T17230 2355-2360 Protein denotes STAT3
T17229 2309-2313 Protein denotes IL-6
T17228 2229-2234 Protein denotes IL-10
T17227 2184-2188 Protein denotes IL-6
T17226 2117-2122 Protein denotes IFN-γ
T17225 2088-2093 Protein denotes IL-10
T17224 2046-2050 Protein denotes IL-6
T17223 2006-2011 Protein denotes IFN-γ
T17222 1978-1983 Protein denotes IL-10
T17221 1921-1925 Protein denotes CD28
T17220 1881-1884 Protein denotes CD4
T17219 1855-1859 Protein denotes IL-6
T17218 1796-1799 Protein denotes CD4
T17217 1776-1781 Protein denotes IFN-γ
T17216 1759-1764 Protein denotes IL-10
T17215 1725-1729 Protein denotes IL-6
T17214 1656-1661 Protein denotes STAT1
T17213 1616-1621 Protein denotes STAT3
T17212 1582-1587 Protein denotes STAT1
T17211 1557-1561 Protein denotes IL-6
T17210 1484-1489 Protein denotes STAT1
T17209 1407-1412 Protein denotes STAT3
T17208 1386-1390 Protein denotes IL-6
T17207 1333-1337 Protein denotes IL-6
T17206 1274-1279 Protein denotes STAT3
T17205 1258-1263 Protein denotes STAT1
T17204 1244-1249 Protein denotes STAT3
T17203 1089-1093 Protein denotes IL-6
T17202 958-961 Protein denotes CD4
T17201 875-878 Protein denotes CD4
T17200 860-864 Protein denotes IL-6
T17199 821-826 Protein denotes STAT3
T17198 811-816 Protein denotes STAT1
T17197 775-780 Protein denotes IL-10
T17196 740-745 Protein denotes STAT3
T17195 674-678 Protein denotes IL-6
T17194 635-638 Protein denotes CD4
T17193 500-504 Protein denotes IL-6
T17192 461-466 Protein denotes STAT3
T17191 375-379 Protein denotes IL-6
T17190 320-325 Protein denotes IL-10
T17189 280-303 Protein denotes epidermal growth factor
T17188 244-274 Protein denotes platelet-derived growth factor
T17187 229-241 Protein denotes oncostatin M
T17186 197-223 Protein denotes leukemia inhibitory factor
T17185 190-195 Protein denotes IL-11
T17184 184-188 Protein denotes IL-6
T17183 90-95 Protein denotes STAT3
T17182 77-80 Protein denotes CD4
T17181 54-59 Protein denotes IL-10
T17180 14-19 Protein denotes STAT3
T17179 0-4 Protein denotes IL-6
T17178 1782-1792 Gene_expression denotes production
R8725 T17178 T17255 themeOf production,inhibit
R8726 T17179 T17233 causeOf IL-6,mediated
R8727 T17180 T17234 themeOf STAT3,phosphorylation
R8728 T17181 T17235 themeOf IL-10,inhibition
R8729 T17183 T17237 themeOf STAT3,activated
R8730 T17185 T17237 causeOf IL-11,activated
R8731 T17186 T17237 causeOf leukemia inhibitory factor,activated
R8732 T17187 T17237 causeOf oncostatin M,activated
R8733 T17188 T17237 causeOf platelet-derived growth factor,activated
R8734 T17189 T17238 causeOf epidermal growth factor,induces
R8735 T17189 T17237 causeOf epidermal growth factor,activated
R8736 T17190 T17237 causeOf IL-10,activated
R8737 T17191 T17238 causeOf IL-6,induces
R8738 T17191 T17237 causeOf IL-6,activated
R8739 T17192 T17239 themeOf STAT3,activation
R8740 T17196 T17241 themeOf STAT3,activation
R8741 T17197 T17242 themeOf IL-10,inhibition
R8742 T17198 T17243 themeOf STAT1,phosphorylation
R8743 T17199 T17243 themeOf STAT3,phosphorylation
R8744 T17200 T17244 causeOf IL-6,activated
R8745 T17204 T17247 themeOf STAT3,phosphorylation
R8746 T17205 T17247 themeOf STAT1,phosphorylation
R8747 T17206 T17248 themeOf STAT3,activation
R8748 T17207 T17250 themeOf IL-6,neutralization
R8749 T17213 T17252 themeOf STAT3,activation
R8750 T17215 T17255 causeOf IL-6,inhibit
R8751 T17215 T17253 causeOf IL-6,suppress
R8752 T17216 T17255 causeOf IL-10,inhibit
R8753 T17217 T17178 themeOf IFN-γ,production
R8754 T17223 T17256 themeOf IFN-γ,production
R8755 T17225 T17258 causeOf IL-10,mediated
R8756 T17226 T17260 themeOf IFN-γ,production
R8757 T17229 T17261 causeOf IL-6,role
R8758 T17230 T17263 themeOf STAT3,activation
R8759 T17231 T17264 themeOf IL-10,inhibitory effect
R8760 T17234 T17233 themeOf phosphorylation,mediated
R8761 T17239 T17238 themeOf activation,induces
R8762 T17241 T17240 themeOf activation,responsible
R8763 T17242 T17240 themeOf inhibition,responsible
R8764 T17243 T17244 themeOf phosphorylation,activated
R8765 T17246 T17249 themeOf induce,abolished
R8766 T17247 T17246 themeOf phosphorylation,induce
R8767 T17248 T17249 themeOf activation,abolished
R8768 T17250 T17249 causeOf neutralization,abolished
R8769 T17252 T17251 themeOf activation,required
R8770 T17258 T17257 themeOf mediated,reduced
R8771 T17259 T17257 themeOf inhibition,reduced
R8772 T17259 T17258 themeOf inhibition,mediated
R8773 T17260 T17259 themeOf production,inhibition
R8774 T17262 T17261 themeOf induction,role
R8775 T17263 T17262 themeOf activation,induction