PMC:1064873 / 1693-3413
Annnotations
LappsTest
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2207 | 1679-1683 | Protein | denotes | IL-6 |
T2206 | 1651-1656 | Protein | denotes | STAT3 |
T2205 | 1620-1624 | Protein | denotes | IL-6 |
T2204 | 1610-1615 | Protein | denotes | IL-10 |
T2203 | 1549-1554 | Protein | denotes | SOCS3 |
T2202 | 1325-1335 | Protein | denotes | JAK kinase |
T2201 | 1263-1267 | Protein | denotes | SOCS |
T2200 | 1171-1175 | Protein | denotes | IL-6 |
T2199 | 1069-1074 | Protein | denotes | IL-10 |
T2198 | 1035-1040 | Protein | denotes | STAT3 |
T2197 | 998-1003 | Protein | denotes | STAT3 |
T2196 | 924-928 | Protein | denotes | IL-6 |
T2195 | 888-919 | Protein | denotes | IL-10-derived anti-inflammatory |
T2194 | 856-861 | Protein | denotes | STAT3 |
T2193 | 723-737 | Protein | denotes | STAT3 proteins |
T2192 | 713-718 | Protein | denotes | STAT1 |
T2191 | 680-685 | Protein | denotes | STAT1 |
T2190 | 668-672 | Protein | denotes | STAT |
T2189 | 587-635 | Protein | denotes | latent transcriptional factors signal transducer |
T2188 | 526-531 | Protein | denotes | IL-10 |
T2187 | 481-488 | Protein | denotes | IL-10R1 |
T2186 | 434-438 | Protein | denotes | Tyk2 |
T2185 | 425-429 | Protein | denotes | Jak1 |
T2184 | 396-399 | Protein | denotes | JAK |
T2183 | 382-394 | Protein | denotes | Janus kinase |
T2182 | 363-369 | Protein | denotes | IL-10R |
T2181 | 353-358 | Protein | denotes | IL-10 |
T2180 | 278-285 | Protein | denotes | IL-10R1 |
T2179 | 263-276 | Protein | denotes | type 1 IL-10R |
T2178 | 176-182 | Protein | denotes | IL-10R |
T2177 | 160-174 | Protein | denotes | IL-10 receptor |
T2176 | 141-146 | Protein | denotes | IL-10 |
T2175 | 0-5 | Protein | denotes | IL-10 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
15535835-11244051-4156862 | 330-331 | 11244051 | denotes | 1 |
15535835-10347215-4156863 | 522-523 | 10347215 | denotes | 2 |
15535835-7543512-4156864 | 687-688 | 7543512 | denotes | 3 |
15535835-12039028-4156865 | 964-965 | 12039028 | denotes | 4 |
15535835-10023769-4156866 | 1144-1145 | 10023769 | denotes | 5 |
15535835-9794394-4156867 | 1221-1222 | 9794394 | denotes | 6 |
15535835-11527983-4156868 | 1516-1517 | 11527983 | denotes | 7 |
15535835-12754507-4156869 | 1715-1716 | 12754507 | denotes | 8 |
15535835-12626585-4156870 | 1717-1718 | 12626585 | denotes | 9 |
biosemtest
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3113 | 540-564 | UMLS/C1519726 | denotes | tyrosine phosphorylation |
T3109 | 1476-1494 | UMLS/C0037080 | denotes | signaling pathways |
T3101 | 813-821 | UMLS/C0443264 | denotes | modulate |
T3100 | 1229-1261 | UP/Q62225 | denotes | suppressor of cytokine signaling |
T3094 | 1325-1335 | UMLS/C0597721 | denotes | JAK kinase |
T3093 | 382-394 | UMLS/C0597721 | denotes | Janus kinase |
T3091 | 1590-1599 | UMLS/C0443204 | denotes | divergent |
T3080 | 305-314 | UMLS/C1705248 | denotes | component |
T3079 | 253-262 | UMLS/C1705248 | denotes | component |
T3076 | 668-672 | UMLS/C1548425 | denotes | STAT |
T3075 | 160-174 | UMLS/C0247771 | denotes | IL-10 receptor |
T3052 | 1155-1166 | UMLS/C1273518 | denotes | responsible |
T3047 | 1527-1534 | UMLS/C2603343 | denotes | studies |
T3046 | 968-975 | UMLS/C2603343 | denotes | Studies |
T3045 | 1131-1142 | UMLS/C0027950 | denotes | neutrophils |
T3041 | 1527-1534 | UMLS/C2349977 | denotes | studies |
T3040 | 968-975 | UMLS/C2349977 | denotes | Studies |
T3036 | 738-742 | UMLS/C0348078 | denotes | form |
T3033 | 396-399 | UMLS/C1150611 | denotes | JAK |
T3027 | 1642-1650 | UMLS/C0332206 | denotes | blocking |
T3020 | 822-840 | UMLS/C0040649 | denotes | gene transcription |
T3019 | 594-609 | UMLS/C0040649 | denotes | transcriptional |
T3013 | 713-718 | UP/P42229 | denotes | STAT1 |
T3012 | 680-685 | UP/P42229 | denotes | STAT1 |
T3008 | 1535-1543 | UMLS/C1444656 | denotes | indicate |
T3007 | 408-424 | UMLS/C0033681 | denotes | tyrosine kinases |
T3005 | 953-962 | UMLS/C1704632 | denotes | responses |
T3002 | 1600-1606 | UMLS/C0441472 | denotes | action |
T3000 | 184-191 | UMLS/C0439855 | denotes | complex |
T2998 | 1476-1494 | UMLS/C0086982 | denotes | signaling pathways |
T2995 | 1520-1526 | UMLS/C0332185 | denotes | Recent |
T2990 | 1363-1370 | UMLS/C0439858 | denotes | classic |
T2968 | 1708-1713 | UMLS/C0085295 | denotes | IL-10 |
T2967 | 1610-1615 | UMLS/C0085295 | denotes | IL-10 |
T2966 | 1069-1074 | UMLS/C0085295 | denotes | IL-10 |
T2965 | 888-893 | UMLS/C0085295 | denotes | IL-10 |
T2964 | 526-531 | UMLS/C0085295 | denotes | IL-10 |
T2963 | 353-358 | UMLS/C0085295 | denotes | IL-10 |
T2962 | 0-5 | UMLS/C0085295 | denotes | IL-10 |
T2956 | 1229-1261 | UMLS/C0299250 | denotes | suppressor of cytokine signaling |
T2953 | 1176-1184 | UMLS/C0086597 | denotes | mediated |
T2952 | 1075-1083 | UMLS/C0086597 | denotes | mediated |
T2950 | 305-314 | UMLS/C1179435 | denotes | component |
T2949 | 253-262 | UMLS/C1179435 | denotes | component |
T2948 | 1229-1261 | UP/Q9PW70 | denotes | suppressor of cytokine signaling |
T2937 | 696-711 | UMLS/C0031715 | denotes | phosphorylation |
T2935 | 305-314 | UMLS/C0729650 | denotes | component |
T2934 | 253-262 | UMLS/C0729650 | denotes | component |
T2933 | 1304-1310 | UMLS/C1563343 | denotes | family |
T2932 | 401-407 | UMLS/C1563343 | denotes | family |
T2931 | 338-349 | UMLS/C1704675 | denotes | interaction |
T2930 | 1555-1560 | UMLS/C0331781 | denotes | plays |
T2927 | 953-962 | UMLS/C0871261 | denotes | responses |
T2926 | 1288-1298 | UMLS/C1551388 | denotes | identified |
T2921 | 1304-1310 | UMLS/C1704727 | denotes | family |
T2920 | 401-407 | UMLS/C1704727 | denotes | family |
T2911 | 1084-1101 | UMLS/C0003209 | denotes | anti-inflammatory |
T2910 | 902-919 | UMLS/C0003209 | denotes | anti-inflammatory |
T2837 | 894-901 | UMLS/C2348040 | denotes | derived |
T2834 | 1444-1454 | UMLS/C1628982 | denotes | inhibition |
T2825 | 1527-1534 | UMLS/C1705923 | denotes | studies |
T2824 | 968-975 | UMLS/C1705923 | denotes | Studies |
T2822 | 813-821 | UMLS/C1709059 | denotes | modulate |
T2820 | 1651-1656 | UMLS/C1367307 | denotes | STAT3 |
T2819 | 1035-1040 | UMLS/C1367307 | denotes | STAT3 |
T2818 | 856-861 | UMLS/C1367307 | denotes | STAT3 |
T2816 | 230-237 | UMLS/C0439631 | denotes | primary |
T2806 | 953-962 | UMLS/C1706817 | denotes | responses |
T2804 | 212-215 | UMLS/C0205448 | denotes | two |
T2803 | 1363-1370 | UMLS/C0439658 | denotes | classic |
T2802 | 1563-1566 | UMLS/C1554080 | denotes | key |
T2801 | 11-14 | UMLS/C1554080 | denotes | key |
T2795 | 1352-1355 | UMLS/C0006823 | denotes | can |
T2784 | 1115-1126 | UMLS/C1550652 | denotes | macrophages |
T2783 | 1229-1261 | UP/O70512 | denotes | suppressor of cytokine signaling |
T2775 | 738-742 | UMLS/C1522492 | denotes | form |
T2774 | 738-742 | UMLS/C0205431 | denotes | form |
T2772 | 1651-1656 | UMLS/C0253050 | denotes | STAT3 |
T2771 | 1035-1040 | UMLS/C0253050 | denotes | STAT3 |
T2770 | 856-861 | UMLS/C0253050 | denotes | STAT3 |
T2769 | 723-737 | UMLS/C0253050 | denotes | STAT3 proteins |
T2759 | 1288-1298 | UMLS/C0205396 | denotes | identified |
T2753 | 1444-1454 | UMLS/C0021467 | denotes | inhibition |
T2748 | 1444-1454 | UMLS/C0021469 | denotes | inhibition |
T2747 | 72-82 | UMLS/C0021469 | denotes | inhibiting |
T2738 | 1371-1390 | UMLS/C0678613 | denotes | feedback inhibition |
T2733 | 1555-1560 | UMLS/C0032214 | denotes | plays |
T2729 | 1527-1534 | UMLS/C0557651 | denotes | studies |
T2728 | 968-975 | UMLS/C0557651 | denotes | Studies |
T2726 | 1567-1571 | UMLS/C1705809 | denotes | role |
T2725 | 1408-1413 | UMLS/C1705809 | denotes | roles |
T2724 | 1467-1485 | UMLS/C1511617 | denotes | cytokine signaling |
T2722 | 989-997 | UMLS/C0205369 | denotes | specific |
T2720 | 1567-1571 | UMLS/C1705812 | denotes | role |
T2719 | 1408-1413 | UMLS/C1705812 | denotes | roles |
T2716 | 1567-1571 | UMLS/C1705810 | denotes | role |
T2715 | 1408-1413 | UMLS/C1705810 | denotes | roles |
T2713 | 1567-1571 | UMLS/C1705811 | denotes | role |
T2712 | 1408-1413 | UMLS/C1705811 | denotes | roles |
T2700 | 1199-1208 | UMLS/C0162638 | denotes | apoptosis |
T2689 | 1708-1713 | UMLS/C1149215 | denotes | IL-10 |
T2688 | 1610-1615 | UMLS/C1149215 | denotes | IL-10 |
T2687 | 1069-1074 | UMLS/C1149215 | denotes | IL-10 |
T2686 | 888-893 | UMLS/C1149215 | denotes | IL-10 |
T2685 | 526-531 | UMLS/C1149215 | denotes | IL-10 |
T2684 | 353-358 | UMLS/C1149215 | denotes | IL-10 |
T2683 | 141-152 | UMLS/C1149215 | denotes | IL-10 binds |
T2682 | 0-5 | UMLS/C1149215 | denotes | IL-10 |
T2679 | 1567-1571 | UMLS/C0035820 | denotes | role |
T2678 | 1408-1413 | UMLS/C0035820 | denotes | roles |
T2673 | 771-778 | UMLS/C1637379 | denotes | rapidly |
T2670 | 1555-1560 | UMLS/C0600138 | denotes | plays |
T2666 | 1679-1683 | UMLS/C1149241 | denotes | IL-6 |
T2665 | 1620-1624 | UMLS/C1149241 | denotes | IL-6 |
T2664 | 1171-1175 | UMLS/C1149241 | denotes | IL-6 |
T2663 | 924-928 | UMLS/C1149241 | denotes | IL-6 |
T2661 | 713-718 | UMLS/C1335872 | denotes | STAT1 |
T2660 | 680-685 | UMLS/C1335872 | denotes | STAT1 |
T3233 | 800-807 | UMLS/C0007610 | denotes | nucleus |
T3223 | 87-97 | UMLS/C1548180 | denotes | production |
T3222 | 1102-1111 | UMLS/C1114821 | denotes | reactions |
T3219 | 1421-1430 | UMLS/C1363844 | denotes | mediators |
T3218 | 338-349 | UMLS/C1546938 | denotes | interaction |
T3215 | 1575-1585 | UMLS/C0851285 | denotes | regulating |
T3214 | 27-37 | UMLS/C0851285 | denotes | regulating |
T3213 | 1356-1359 | UMLS/C1551336 | denotes | act |
T3206 | 1549-1554 | UMLS/C1426212 | denotes | SOCS3 |
T3205 | 1304-1310 | UMLS/C1555907 | denotes | family |
T3204 | 401-407 | UMLS/C1555907 | denotes | family |
T3202 | 238-252 | UMLS/C1517880 | denotes | ligand-binding |
T3190 | 1115-1126 | UMLS/C0024432 | denotes | macrophages |
T3188 | 738-742 | UMLS/C0013058 | denotes | form |
T3177 | 668-672 | UMLS/C1366753 | denotes | STAT |
T3176 | 618-666 | UMLS/C1366753 | denotes | signal transducer and activator of transcription |
T3174 | 1185-1195 | UMLS/C1708528 | denotes | prevention |
T3173 | 1304-1310 | UMLS/C1552262 | denotes | family |
T3172 | 401-407 | UMLS/C1552262 | denotes | family |
T3171 | 1102-1111 | UMLS/C0443286 | denotes | reactions |
T3165 | 184-191 | UMLS/C1704241 | denotes | complex |
T3156 | 1352-1355 | UMLS/C0344312 | denotes | can |
T3155 | 1304-1310 | UMLS/C2700055 | denotes | family |
T3154 | 401-407 | UMLS/C2700055 | denotes | family |
T3152 | 713-718 | UP/P42224 | denotes | STAT1 |
T3151 | 1567-1571 | UMLS/C1704326 | denotes | role |
T3150 | 1408-1413 | UMLS/C1704326 | denotes | roles |
T3149 | 1131-1142 | UMLS/C0948762 | denotes | neutrophils |
T3134 | 102-110 | UMLS/C1705273 | denotes | function |
T3131 | 1263-1277 | UMLS/C1564682 | denotes | SOCS) proteins |
T3119 | 1212-1219 | UMLS/C0039194 | denotes | T cells |
T3117 | 680-685 | UP/P42224 | denotes | STAT1 |
T3114 | 102-110 | UMLS/C0542341 | denotes | function |
T2651 | 500-506 | UMLS/C1149187 | denotes | IL-10R |
T2650 | 363-369 | UMLS/C1149187 | denotes | IL-10R |
T2649 | 322-328 | UMLS/C1149187 | denotes | IL-10R |
T2648 | 270-276 | UMLS/C1149187 | denotes | IL-10R |
T2647 | 176-182 | UMLS/C1149187 | denotes | IL-10R |
T2645 | 929-936 | UMLS/C1711343 | denotes | derived |
T2644 | 894-901 | UMLS/C1711343 | denotes | derived |
T2639 | 1657-1667 | UMLS/C1879547 | denotes | activation |
T2638 | 1041-1051 | UMLS/C1879547 | denotes | activation |
T2637 | 569-579 | UMLS/C1879547 | denotes | activation |
T2634 | 1304-1310 | UMLS/C0015576 | denotes | family |
T2633 | 401-407 | UMLS/C0015576 | denotes | family |
T2632 | 1527-1534 | UMLS/C0008972 | denotes | studies |
T2631 | 968-975 | UMLS/C0008972 | denotes | Studies |
T2630 | 1527-1534 | UMLS/C0008976 | denotes | studies |
T2629 | 968-975 | UMLS/C0008976 | denotes | Studies |
T2625 | 1679-1683 | UMLS/C1527132 | denotes | IL-6 |
T2624 | 1620-1624 | UMLS/C1527132 | denotes | IL-6 |
T2623 | 1171-1175 | UMLS/C1527132 | denotes | IL-6 |
T2622 | 924-928 | UMLS/C1527132 | denotes | IL-6 |
T2887 | 929-936 | UMLS/C1441547 | denotes | derived |
T2886 | 894-901 | UMLS/C1441547 | denotes | derived |
T2885 | 1391-1396 | UMLS/C0445022 | denotes | loops |
T2883 | 587-593 | UMLS/C0205275 | denotes | latent |
T2881 | 465-480 | UMLS/C0332281 | denotes | associated with |
T2880 | 1688-1691 | UMLS/C1518422 | denotes | not |
T2876 | 989-997 | UMLS/C1552740 | denotes | specific |
T2869 | 1697-1704 | UMLS/C0205263 | denotes | induced |
T2868 | 1668-1675 | UMLS/C0205263 | denotes | induced |
T2867 | 532-539 | UMLS/C0205263 | denotes | induces |
T2862 | 305-314 | UMLS/C0449432 | denotes | component |
T2861 | 253-262 | UMLS/C0449432 | denotes | component |
T2859 | 1185-1195 | UMLS/C2700409 | denotes | prevention |
T2843 | 1055-1064 | UMLS/C0205224 | denotes | essential |
T2840 | 1314-1324 | UMLS/C0205227 | denotes | endogenous |
T2839 | 230-237 | UMLS/C0205225 | denotes | primary |
T2838 | 929-936 | UMLS/C2348040 | denotes | derived |
T2621 | 1288-1298 | UMLS/C1550043 | denotes | identified |
T2620 | 1329-1346 | UMLS/C1152564 | denotes | kinase inhibitors |
T2618 | 668-672 | UMLS/C0205548 | denotes | STAT |
T2603 | 38-60 | UMLS/C1155266 | denotes | inflammatory responses |
T2596 | 1708-1713 | UMLS/C1522550 | denotes | IL-10 |
T2595 | 1610-1615 | UMLS/C1522550 | denotes | IL-10 |
T2594 | 1069-1074 | UMLS/C1522550 | denotes | IL-10 |
T2593 | 888-893 | UMLS/C1522550 | denotes | IL-10 |
T2592 | 526-531 | UMLS/C1522550 | denotes | IL-10 |
T2591 | 353-358 | UMLS/C1522550 | denotes | IL-10 |
T2590 | 0-5 | UMLS/C1522550 | denotes | IL-10 |
T2582 | 1708-1713 | UMLS/C1334098 | denotes | IL-10 |
T2581 | 1610-1615 | UMLS/C1334098 | denotes | IL-10 |
T2580 | 1069-1074 | UMLS/C1334098 | denotes | IL-10 |
T2579 | 888-893 | UMLS/C1334098 | denotes | IL-10 |
T2578 | 526-531 | UMLS/C1334098 | denotes | IL-10 |
T2577 | 353-358 | UMLS/C1334098 | denotes | IL-10 |
T2576 | 0-5 | UMLS/C1334098 | denotes | IL-10 |
T2574 | 1391-1396 | UMLS/C1881441 | denotes | loops |
T2563 | 130-139 | UMLS/C1524094 | denotes | cytokines |
T2562 | 15-23 | UMLS/C1524094 | denotes | cytokine |
T2559 | 1329-1346 | UMLS/C1171350 | denotes | kinase inhibitors |
T2555 | 1679-1683 | UMLS/C0021760 | denotes | IL-6 |
T2554 | 1620-1624 | UMLS/C0021760 | denotes | IL-6 |
T2553 | 1171-1175 | UMLS/C0021760 | denotes | IL-6 |
T2552 | 924-928 | UMLS/C0021760 | denotes | IL-6 |
T2542 | 1679-1683 | UMLS/C1334122 | denotes | IL-6 |
T2541 | 1620-1624 | UMLS/C1334122 | denotes | IL-6 |
T2540 | 1171-1175 | UMLS/C1334122 | denotes | IL-6 |
T2539 | 924-928 | UMLS/C1334122 | denotes | IL-6 |
T2538 | 1563-1566 | UMLS/C1706198 | denotes | key |
T2537 | 11-14 | UMLS/C1706198 | denotes | key |
T2530 | 668-672 | UMLS/C1335960 | denotes | STAT |
T2527 | 1185-1195 | UMLS/C0199176 | denotes | prevention |
T2522 | 668-672 | UMLS/C1420304 | denotes | STAT |
T2521 | 338-349 | UMLS/C0687133 | denotes | interaction |
T2512 | 1642-1650 | UMLS/C1706084 | denotes | blocking |
T2501 | 1642-1650 | UMLS/C1533157 | denotes | blocking |
T2499 | 1527-1534 | UMLS/C1880229 | denotes | studies |
T2498 | 968-975 | UMLS/C1880229 | denotes | Studies |
T2494 | 1600-1606 | UMLS/C1552007 | denotes | action |
T2492 | 305-314 | UMLS/C1548799 | denotes | component |
T2491 | 253-262 | UMLS/C1548799 | denotes | component |
T2488 | 1084-1101 | UMLS/C1515999 | denotes | anti-inflammatory |
T2487 | 902-919 | UMLS/C1515999 | denotes | anti-inflammatory |
T2478 | 1684-1687 | UMLS/C0005341 | denotes | but |
T2477 | 1398-1401 | UMLS/C0005341 | denotes | but |
T2476 | 1148-1151 | UMLS/C0005341 | denotes | but |
T2468 | 153-155 | UMLS/C0319022 | denotes | to |
T2465 | 1075-1083 | UMLS/C0127400 | denotes | mediated |
T2462 | 1642-1650 | UMLS/C0028778 | denotes | blocking |
T2455 | 1642-1650 | UMLS/C0233660 | denotes | blocking |
T2453 | 370-377 | UMLS/C0425152 | denotes | engages |
T2451 | 1229-1261 | UP/Q9NSE2 | denotes | suppressor of cytokine signaling |
T2450 | 1527-1534 | UMLS/C0947630 | denotes | studies |
T2449 | 968-975 | UMLS/C0947630 | denotes | Studies |
T2437 | 1421-1430 | UMLS/C0127400 | denotes | mediators |
T2436 | 1176-1184 | UMLS/C0127400 | denotes | mediated |
T2433 | 130-139 | UMLS/C0079189 | denotes | cytokines |
T2432 | 15-23 | UMLS/C0079189 | denotes | cytokine |
T2611 | 1115-1126 | UMLS/C1546706 | denotes | macrophages |
T2608 | 305-314 | UMLS/C1524073 | denotes | component |
T2607 | 253-262 | UMLS/C1524073 | denotes | component |
T2606 | 738-742 | UMLS/C0376315 | denotes | form |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4218 | 1718-1719 | -RRB- | denotes | ] |
T4217 | 1715-1718 | CD | denotes | 8,9 |
T4216 | 1714-1715 | -LRB- | denotes | [ |
T4215 | 1708-1713 | NN | denotes | IL-10 |
T4214 | 1705-1707 | IN | denotes | by |
T4213 | 1697-1704 | VB | denotes | induced |
T4212 | 1692-1696 | DT | denotes | that |
T4211 | 1688-1691 | RB | denotes | not |
T4210 | 1684-1687 | CC | denotes | but |
T4209 | 1679-1683 | NN | denotes | IL-6 |
T4208 | 1676-1678 | IN | denotes | by |
T4207 | 1668-1675 | VB | denotes | induced |
T4206 | 1657-1667 | NN | denotes | activation |
T4205 | 1651-1656 | NN | denotes | STAT3 |
T4204 | 1642-1650 | VB | denotes | blocking |
T4203 | 1629-1641 | RB | denotes | specifically |
T4202 | 1626-1628 | IN | denotes | by |
T4201 | 1624-1625 | -COMMA- | denotes | , |
T4200 | 1620-1624 | NN | denotes | IL-6 |
T4199 | 1616-1619 | CC | denotes | and |
T4198 | 1610-1615 | NN | denotes | IL-10 |
T4197 | 1607-1609 | IN | denotes | of |
T4196 | 1600-1606 | NN | denotes | action |
T4195 | 1590-1599 | JJ | denotes | divergent |
T4194 | 1586-1589 | DT | denotes | the |
T4193 | 1575-1585 | VB | denotes | regulating |
T4192 | 1572-1574 | IN | denotes | in |
T4191 | 1567-1571 | NN | denotes | role |
T4190 | 1563-1566 | JJ | denotes | key |
T4189 | 1561-1562 | DT | denotes | a |
T4188 | 1555-1560 | VB | denotes | plays |
T4187 | 1549-1554 | NN | denotes | SOCS3 |
T4186 | 1544-1548 | IN | denotes | that |
T4185 | 1535-1543 | VB | denotes | indicate |
T4184 | 1527-1534 | NN | denotes | studies |
T4183 | 1520-1526 | JJ | denotes | Recent |
T4182 | 1517-1518 | -RRB- | denotes | ] |
T4181 | 1516-1517 | CD | denotes | 7 |
T4180 | 1515-1516 | -LRB- | denotes | [ |
T4179 | 1505-1514 | VB | denotes | clarified |
T4178 | 1500-1504 | VB | denotes | been |
T4177 | 1495-1499 | VB | denotes | have |
T4176 | 1486-1494 | NN | denotes | pathways |
T4175 | 1476-1485 | NN | denotes | signaling |
T4174 | 1467-1475 | NN | denotes | cytokine |
T4173 | 1458-1466 | VB | denotes | opposing |
T4172 | 1455-1457 | IN | denotes | by |
T4171 | 1444-1454 | NN | denotes | inhibition |
T4170 | 1434-1443 | NN | denotes | crosstalk |
T4169 | 1431-1433 | IN | denotes | of |
T4168 | 1421-1430 | NN | denotes | mediators |
T4167 | 1417-1420 | DT | denotes | the |
T4166 | 1414-1416 | IN | denotes | as |
T4165 | 1408-1413 | NN | denotes | roles |
T4164 | 1402-1407 | PRP-DOLLAR- | denotes | their |
T4163 | 1398-1401 | CC | denotes | but |
T4162 | 1396-1397 | -COMMA- | denotes | , |
T4161 | 1391-1396 | VB | denotes | loops |
T4160 | 1380-1390 | NN | denotes | inhibition |
T4159 | 1371-1379 | NN | denotes | feedback |
T4158 | 1363-1370 | JJ | denotes | classic |
T4157 | 1360-1362 | IN | denotes | in |
T4156 | 1356-1359 | VB | denotes | act |
T4155 | 1352-1355 | MD | denotes | can |
T4154 | 1347-1351 | WDT | denotes | that |
T4153 | 1336-1346 | NN | denotes | inhibitors |
T4152 | 1329-1335 | NN | denotes | kinase |
T4151 | 1325-1328 | NN | denotes | JAK |
T4150 | 1314-1324 | JJ | denotes | endogenous |
T4149 | 1311-1313 | IN | denotes | of |
T4148 | 1304-1310 | NN | denotes | family |
T4147 | 1302-1303 | DT | denotes | a |
T4146 | 1299-1301 | IN | denotes | as |
T4145 | 1288-1298 | VB | denotes | identified |
T4144 | 1283-1287 | VB | denotes | been |
T4143 | 1278-1282 | VB | denotes | have |
T4142 | 1269-1277 | NN | denotes | proteins |
T4141 | 1267-1268 | -RRB- | denotes | ) |
T4140 | 1263-1267 | NN | denotes | SOCS |
T4139 | 1262-1263 | -LRB- | denotes | ( |
T4138 | 1252-1261 | NN | denotes | signaling |
T4137 | 1243-1251 | NN | denotes | cytokine |
T4136 | 1240-1242 | IN | denotes | of |
T4135 | 1229-1239 | NN | denotes | suppressor |
T4134 | 1225-1228 | DT | denotes | The |
T4133 | 1222-1223 | -RRB- | denotes | ] |
T4132 | 1221-1222 | CD | denotes | 6 |
T4131 | 1220-1221 | -LRB- | denotes | [ |
T4130 | 1214-1219 | NN | denotes | cells |
T4129 | 1212-1213 | NN | denotes | T |
T4128 | 1209-1211 | IN | denotes | in |
T4127 | 1199-1208 | NN | denotes | apoptosis |
T4126 | 1196-1198 | IN | denotes | of |
T4125 | 1185-1195 | NN | denotes | prevention |
T4124 | 1171-1184 | JJ | denotes | IL-6-mediated |
T4123 | 1167-1170 | IN | denotes | for |
T4122 | 1155-1166 | JJ | denotes | responsible |
T4121 | 1152-1154 | VB | denotes | is |
T4120 | 1148-1151 | CC | denotes | but |
T4119 | 1146-1147 | -COMMA- | denotes | , |
T4118 | 1145-1146 | -RRB- | denotes | ] |
T4117 | 1144-1145 | CD | denotes | 5 |
T4116 | 1143-1144 | -LRB- | denotes | [ |
T4115 | 1131-1142 | NN | denotes | neutrophils |
T4114 | 1127-1130 | CC | denotes | and |
T4113 | 1115-1126 | NN | denotes | macrophages |
T4112 | 1112-1114 | IN | denotes | in |
T4111 | 1102-1111 | NN | denotes | reactions |
T4110 | 1084-1101 | JJ | denotes | anti-inflammatory |
T4109 | 1069-1083 | JJ | denotes | IL-10-mediated |
T4108 | 1065-1068 | IN | denotes | for |
T4107 | 1055-1064 | JJ | denotes | essential |
T4106 | 1052-1054 | VB | denotes | is |
T4105 | 1041-1051 | NN | denotes | activation |
T4104 | 1035-1040 | NN | denotes | STAT3 |
T4103 | 1030-1034 | IN | denotes | that |
T4102 | 1024-1029 | VB | denotes | shown |
T4101 | 1019-1023 | VB | denotes | have |
T4100 | 1014-1018 | NN | denotes | mice |
T4099 | 998-1013 | JJ | denotes | STAT3-deficient |
T4098 | 979-997 | JJ | denotes | cell-type-specific |
T4097 | 976-978 | IN | denotes | of |
T4096 | 968-975 | NN | denotes | Studies |
T4095 | 965-966 | -RRB- | denotes | ] |
T4094 | 964-965 | CD | denotes | 4 |
T4093 | 963-964 | -LRB- | denotes | [ |
T4092 | 953-962 | NN | denotes | responses |
T4091 | 937-952 | JJ | denotes | proinflammatory |
T4090 | 924-936 | JJ | denotes | IL-6-derived |
T4089 | 920-923 | CC | denotes | and |
T4088 | 902-919 | JJ | denotes | anti-inflammatory |
T4087 | 888-901 | JJ | denotes | IL-10-derived |
T4086 | 883-887 | DT | denotes | both |
T4085 | 879-882 | IN | denotes | for |
T4084 | 865-878 | JJ | denotes | indispensable |
T4083 | 862-864 | VB | denotes | is |
T4082 | 856-861 | NN | denotes | STAT3 |
T4081 | 854-855 | -COMMA- | denotes | , |
T4080 | 842-854 | RB | denotes | Intriguingly |
T4079 | 827-840 | NN | denotes | transcription |
T4078 | 822-826 | NN | denotes | gene |
T4077 | 813-821 | VB | denotes | modulate |
T4076 | 809-812 | CC | denotes | and |
T4075 | 807-808 | -COMMA- | denotes | , |
T4074 | 800-807 | NN | denotes | nucleus |
T4073 | 796-799 | DT | denotes | the |
T4072 | 791-795 | IN | denotes | into |
T4071 | 779-790 | VB | denotes | translocate |
T4070 | 771-778 | RB | denotes | rapidly |
T4069 | 769-770 | -COMMA- | denotes | , |
T4068 | 757-769 | NN | denotes | heterodimers |
T4067 | 754-756 | CC | denotes | or |
T4066 | 743-753 | NN | denotes | homodimers |
T4065 | 738-742 | VB | denotes | form |
T4064 | 729-737 | NN | denotes | proteins |
T4063 | 723-728 | NN | denotes | STAT3 |
T4062 | 719-722 | CC | denotes | and |
T4061 | 713-718 | NN | denotes | STAT1 |
T4060 | 711-712 | -COMMA- | denotes | , |
T4059 | 696-711 | NN | denotes | phosphorylation |
T4058 | 691-695 | IN | denotes | Upon |
T4057 | 688-689 | -RRB- | denotes | ] |
T4056 | 687-688 | CD | denotes | 3 |
T4055 | 686-687 | -LRB- | denotes | [ |
T4054 | 680-685 | NN | denotes | STAT1 |
T4053 | 676-679 | CC | denotes | and |
T4052 | 674-675 | CD | denotes | 3 |
T4051 | 672-673 | -RRB- | denotes | ) |
T4050 | 668-672 | NN | denotes | STAT |
T4049 | 667-668 | -LRB- | denotes | ( |
T4048 | 653-666 | NN | denotes | transcription |
T4047 | 650-652 | IN | denotes | of |
T4046 | 640-649 | NN | denotes | activator |
T4045 | 636-639 | CC | denotes | and |
T4044 | 625-635 | NN | denotes | transducer |
T4043 | 618-624 | NN | denotes | signal |
T4042 | 610-617 | NN | denotes | factors |
T4041 | 594-609 | JJ | denotes | transcriptional |
T4040 | 587-593 | JJ | denotes | latent |
T4039 | 583-586 | DT | denotes | the |
T4038 | 580-582 | IN | denotes | of |
T4037 | 569-579 | NN | denotes | activation |
T4036 | 565-568 | CC | denotes | and |
T4035 | 549-564 | NN | denotes | phosphorylation |
T4034 | 540-548 | NN | denotes | tyrosine |
T4033 | 532-539 | VB | denotes | induces |
T4032 | 526-531 | NN | denotes | IL-10 |
T4031 | 523-524 | -RRB- | denotes | ] |
T4030 | 522-523 | CD | denotes | 2 |
T4029 | 521-522 | -LRB- | denotes | [ |
T4028 | 508-520 | RB | denotes | respectively |
T4027 | 506-507 | -COMMA- | denotes | , |
T4026 | 500-506 | NN | denotes | IL-10R |
T4025 | 498-499 | CD | denotes | 2 |
T4024 | 493-497 | NN | denotes | type |
T4023 | 489-492 | CC | denotes | and |
T4022 | 481-488 | NN | denotes | IL-10R1 |
T4021 | 476-480 | IN | denotes | with |
T4020 | 465-475 | VB | denotes | associated |
T4019 | 450-464 | RB | denotes | constitutively |
T4018 | 446-449 | VB | denotes | are |
T4017 | 440-445 | WDT | denotes | which |
T4016 | 438-439 | -COMMA- | denotes | , |
T4015 | 434-438 | NN | denotes | Tyk2 |
T4014 | 430-433 | CC | denotes | and |
T4013 | 425-429 | NN | denotes | Jak1 |
T4012 | 417-424 | NN | denotes | kinases |
T4011 | 408-416 | NN | denotes | tyrosine |
T4010 | 401-407 | NN | denotes | family |
T4009 | 399-400 | -RRB- | denotes | ) |
T4008 | 396-399 | NN | denotes | JAK |
T4007 | 395-396 | -LRB- | denotes | ( |
T4006 | 388-394 | NN | denotes | kinase |
T4005 | 382-387 | NN | denotes | Janus |
T4004 | 378-381 | DT | denotes | the |
T4003 | 370-377 | VB | denotes | engages |
T4002 | 363-369 | NN | denotes | IL-10R |
T4001 | 359-362 | CC | denotes | and |
T4000 | 353-358 | NN | denotes | IL-10 |
T3999 | 350-352 | IN | denotes | of |
T3998 | 338-349 | NN | denotes | interaction |
T3997 | 334-337 | DT | denotes | The |
T3996 | 331-332 | -RRB- | denotes | ] |
T3995 | 330-331 | CD | denotes | 1 |
T3994 | 329-330 | -LRB- | denotes | [ |
T3956 | 102-110 | NN | denotes | function |
T3955 | 98-101 | CC | denotes | and |
T3954 | 87-97 | NN | denotes | production |
T3953 | 83-86 | DT | denotes | the |
T3952 | 72-82 | VB | denotes | inhibiting |
T3993 | 322-328 | NN | denotes | IL-10R |
T3992 | 320-321 | CD | denotes | 2 |
T3991 | 315-319 | NN | denotes | type |
T3990 | 305-314 | NN | denotes | component |
T3989 | 295-304 | JJ | denotes | accessory |
T3988 | 291-294 | DT | denotes | the |
T3987 | 287-290 | CC | denotes | and |
T3986 | 285-286 | -RRB- | denotes | ) |
T3985 | 278-285 | NN | denotes | IL-10R1 |
T3984 | 277-278 | -LRB- | denotes | ( |
T3983 | 270-276 | NN | denotes | IL-10R |
T3982 | 268-269 | CD | denotes | 1 |
T3981 | 263-267 | NN | denotes | type |
T3980 | 253-262 | NN | denotes | component |
T3979 | 238-252 | JJ | denotes | ligand-binding |
T3978 | 230-237 | JJ | denotes | primary |
T3977 | 226-229 | DT | denotes | the |
T3976 | 224-225 | -COMMA- | denotes | , |
T3975 | 216-224 | NN | denotes | subunits |
T3974 | 212-215 | CD | denotes | two |
T3973 | 209-211 | IN | denotes | of |
T3972 | 200-208 | VB | denotes | composed |
T3971 | 197-199 | VB | denotes | is |
T3970 | 192-196 | WDT | denotes | that |
T3969 | 184-191 | NN | denotes | complex |
T3968 | 182-183 | -RRB- | denotes | ) |
T3967 | 176-182 | NN | denotes | IL-10R |
T3966 | 175-176 | -LRB- | denotes | ( |
T3965 | 166-174 | NN | denotes | receptor |
T3964 | 160-165 | NN | denotes | IL-10 |
T3963 | 156-159 | DT | denotes | the |
T3962 | 153-155 | TO | denotes | to |
T3961 | 147-152 | VB | denotes | binds |
T3960 | 141-146 | NN | denotes | IL-10 |
T3959 | 130-139 | NN | denotes | cytokines |
T3958 | 114-129 | JJ | denotes | proinflammatory |
T3957 | 111-113 | IN | denotes | of |
T3951 | 69-71 | IN | denotes | by |
T3950 | 62-68 | RB | denotes | mainly |
T3949 | 60-61 | -COMMA- | denotes | , |
T3948 | 51-60 | NN | denotes | responses |
T3947 | 38-50 | JJ | denotes | inflammatory |
T3946 | 27-37 | VB | denotes | regulating |
T3945 | 24-26 | IN | denotes | in |
T3944 | 15-23 | NN | denotes | cytokine |
T3943 | 11-14 | JJ | denotes | key |
T3942 | 9-10 | DT | denotes | a |
T3941 | 6-8 | VB | denotes | is |
T3940 | 0-5 | NN | denotes | IL-10 |
R1040 | T4050 | T4049 | arg2Of | STAT,( |
R1041 | T4051 | T4049 | arg3Of | ),( |
R1042 | T4053 | T4033 | arg2Of | and,induces |
R1043 | T4054 | T4053 | arg2Of | STAT1,and |
R1044 | T4054 | T4055 | arg1Of | STAT1,[ |
R1045 | T4056 | T4055 | arg2Of | 3,[ |
R1047 | T4057 | T4055 | arg3Of | ],[ |
R1052 | T4059 | T4058 | arg2Of | phosphorylation,Upon |
R1056 | T4061 | T4062 | arg1Of | STAT1,and |
R1059 | T4063 | T4062 | arg2Of | STAT3,and |
R1064 | T4064 | T4061 | arg1Of | proteins,STAT1 |
R1073 | T3972 | T3994 | arg1Of | composed,[ |
R1074 | T4064 | T4063 | arg1Of | proteins,STAT3 |
R1075 | T4064 | T4065 | arg1Of | proteins,form |
R1079 | T4064 | T4071 | arg1Of | proteins,translocate |
R1080 | T4064 | T4077 | arg1Of | proteins,modulate |
R1081 | T4065 | T4069 | arg1Of | form,"," |
R1082 | T4066 | T4067 | arg1Of | homodimers,or |
R1083 | T3983 | T3977 | arg1Of | IL-10R,the |
R1084 | T3983 | T3978 | arg1Of | IL-10R,primary |
R1085 | T4067 | T4065 | arg2Of | or,form |
R1086 | T3983 | T3979 | arg1Of | IL-10R,ligand-binding |
R1087 | T3983 | T3980 | arg1Of | IL-10R,component |
R1088 | T3983 | T3981 | arg1Of | IL-10R,type |
R1089 | T3983 | T3982 | arg1Of | IL-10R,1 |
R1090 | T3983 | T3984 | arg1Of | IL-10R,( |
R1091 | T3983 | T3987 | arg1Of | IL-10R,and |
R1092 | T3985 | T3984 | arg2Of | IL-10R1,( |
R1093 | T3986 | T3984 | arg3Of | ),( |
R1095 | T4068 | T4067 | arg2Of | heterodimers,or |
R1096 | T4069 | T4058 | arg1Of | ",",Upon |
R1097 | T3993 | T3987 | arg2Of | IL-10R,and |
R1098 | T3993 | T3988 | arg1Of | IL-10R,the |
R1099 | T3993 | T3989 | arg1Of | IL-10R,accessory |
R1100 | T3993 | T3990 | arg1Of | IL-10R,component |
R1101 | T3993 | T3991 | arg1Of | IL-10R,type |
R1102 | T3993 | T3992 | arg1Of | IL-10R,2 |
R1103 | T3995 | T3994 | arg2Of | 1,[ |
R1104 | T4069 | T4060 | arg1Of | ",","," |
R1105 | T3996 | T3994 | arg3Of | ],[ |
R1106 | T4071 | T4072 | arg1Of | translocate,into |
R1107 | T3998 | T3997 | arg1Of | interaction,The |
R1108 | T3998 | T3999 | arg1Of | interaction,of |
R1109 | T3998 | T4003 | arg1Of | interaction,engages |
R1110 | T4000 | T4001 | arg1Of | IL-10,and |
R1111 | T4071 | T4076 | arg1Of | translocate,and |
R1112 | T4001 | T3999 | arg2Of | and,of |
R1113 | T4002 | T4001 | arg2Of | IL-10R,and |
R1114 | T4074 | T4072 | arg2Of | nucleus,into |
R1115 | T4003 | T4029 | arg1Of | engages,[ |
R1116 | T4006 | T4005 | arg1Of | kinase,Janus |
R1117 | T4006 | T4007 | arg1Of | kinase,( |
R1118 | T4008 | T4007 | arg2Of | JAK,( |
R1119 | T4009 | T4007 | arg3Of | ),( |
R1120 | T4074 | T4073 | arg1Of | nucleus,the |
R1121 | T4076 | T4069 | arg2Of | and,"," |
R1122 | T4013 | T4014 | arg1Of | Jak1,and |
R1123 | T4014 | T4003 | arg2Of | and,engages |
R1124 | T4014 | T4004 | arg1Of | and,the |
R1125 | T4014 | T4006 | arg1Of | and,kinase |
R1126 | T4014 | T4010 | arg1Of | and,family |
R1127 | T4014 | T4011 | arg1Of | and,tyrosine |
R1128 | T4014 | T4012 | arg1Of | and,kinases |
R1129 | T4014 | T4016 | arg1Of | and,"," |
R1130 | T4014 | T4017 | arg1Of | and,which |
R1131 | T4014 | T4018 | arg1Of | and,are |
R1132 | T4014 | T4020 | arg2Of | and,associated |
R1133 | T4014 | T4027 | arg1Of | and,"," |
R1134 | T4014 | T4028 | arg1Of | and,respectively |
R1135 | T4015 | T4014 | arg2Of | Tyk2,and |
R1136 | T4076 | T4070 | arg1Of | and,rapidly |
R1137 | T4020 | T4018 | arg2Of | associated,are |
R1138 | T4020 | T4019 | arg1Of | associated,constitutively |
R1139 | T4020 | T4021 | arg1Of | associated,with |
R1140 | T4076 | T4075 | arg1Of | and,"," |
R1141 | T4022 | T4023 | arg1Of | IL-10R1,and |
R1142 | T4023 | T4021 | arg2Of | and,with |
R1143 | T4077 | T4076 | arg2Of | modulate,and |
R1144 | T4026 | T4023 | arg2Of | IL-10R,and |
R1145 | T4026 | T4024 | arg1Of | IL-10R,type |
R1146 | T4026 | T4025 | arg1Of | IL-10R,2 |
R1147 | T4079 | T4077 | arg2Of | transcription,modulate |
R1148 | T4030 | T4029 | arg2Of | 2,[ |
R1149 | T4079 | T4078 | arg1Of | transcription,gene |
R1150 | T4031 | T4029 | arg3Of | ],[ |
R1151 | T4032 | T4033 | arg1Of | IL-10,induces |
R1152 | T4082 | T4083 | arg1Of | STAT3,is |
R1153 | T4035 | T4034 | arg1Of | phosphorylation,tyrosine |
R1154 | T4035 | T4036 | arg1Of | phosphorylation,and |
R1155 | T4036 | T4038 | arg1Of | and,of |
R1156 | T4082 | T4084 | arg1Of | STAT3,indispensable |
R1157 | T4083 | T4080 | arg1Of | is,Intriguingly |
R1158 | T4036 | T4053 | arg1Of | and,and |
R1159 | T4037 | T4036 | arg2Of | activation,and |
R1160 | T4083 | T4081 | arg1Of | is,"," |
R1161 | T4083 | T4093 | arg1Of | is,[ |
R1162 | T4084 | T4083 | arg2Of | indispensable,is |
R1163 | T4084 | T4085 | arg1Of | indispensable,for |
R1164 | T4088 | T4089 | arg1Of | anti-inflammatory,and |
R1165 | T4044 | T4045 | arg1Of | transducer,and |
R1166 | T4046 | T4045 | arg2Of | activator,and |
R1167 | T4048 | T4038 | arg2Of | transcription,of |
R1168 | T4048 | T4039 | arg1Of | transcription,the |
R1169 | T4048 | T4040 | arg1Of | transcription,latent |
R1170 | T4048 | T4041 | arg1Of | transcription,transcriptional |
R1171 | T4048 | T4042 | arg1Of | transcription,factors |
R1172 | T4048 | T4043 | arg1Of | transcription,signal |
R1173 | T4048 | T4044 | arg1Of | transcription,transducer |
R1174 | T4048 | T4046 | arg1Of | transcription,activator |
R1175 | T4048 | T4047 | arg1Of | transcription,of |
R1176 | T4048 | T4049 | arg1Of | transcription,( |
R1177 | T4048 | T4052 | arg1Of | transcription,3 |
R1178 | T4090 | T4089 | arg2Of | IL-6-derived,and |
R1179 | T4092 | T4085 | arg2Of | responses,for |
R1180 | T4148 | T4146 | arg2Of | family,as |
R1181 | T4148 | T4147 | arg1Of | family,a |
R1182 | T4148 | T4149 | arg1Of | family,of |
R1183 | T4092 | T4086 | arg1Of | responses,both |
R1184 | T4092 | T4087 | arg1Of | responses,IL-10-derived |
R1185 | T4092 | T4088 | arg1Of | responses,anti-inflammatory |
R1186 | T4153 | T4149 | arg2Of | inhibitors,of |
R1187 | T4153 | T4150 | arg1Of | inhibitors,endogenous |
R1188 | T4153 | T4151 | arg1Of | inhibitors,JAK |
R1189 | T4153 | T4152 | arg1Of | inhibitors,kinase |
R1190 | T4153 | T4154 | arg1Of | inhibitors,that |
R1191 | T4153 | T4155 | arg1Of | inhibitors,can |
R1192 | T4153 | T4156 | arg1Of | inhibitors,act |
R1193 | T4092 | T4090 | arg1Of | responses,IL-6-derived |
R1194 | T4156 | T4155 | arg2Of | act,can |
R1195 | T4156 | T4157 | arg1Of | act,in |
R1196 | T4092 | T4091 | arg1Of | responses,proinflammatory |
R1197 | T4094 | T4093 | arg2Of | 4,[ |
R1198 | T4161 | T4157 | arg2Of | loops,in |
R1199 | T4161 | T4158 | arg1Of | loops,classic |
R1200 | T4161 | T4159 | arg1Of | loops,feedback |
R1201 | T4161 | T4160 | arg1Of | loops,inhibition |
R1202 | T4163 | T4162 | arg1Of | but,"," |
R1203 | T4095 | T4093 | arg3Of | ],[ |
R1204 | T4165 | T4164 | arg1Of | roles,their |
R1205 | T4165 | T4166 | arg1Of | roles,as |
R1206 | T4165 | T4177 | arg1Of | roles,have |
R1207 | T4165 | T4178 | arg1Of | roles,been |
R1208 | T4165 | T4179 | arg2Of | roles,clarified |
R1209 | T4096 | T4097 | arg1Of | Studies,of |
R1210 | T4168 | T4166 | arg2Of | mediators,as |
R1211 | T4168 | T4167 | arg1Of | mediators,the |
R1212 | T4168 | T4169 | arg1Of | mediators,of |
R1213 | T4168 | T4172 | arg1Of | mediators,by |
R1214 | T4096 | T4101 | arg1Of | Studies,have |
R1215 | T4171 | T4169 | arg2Of | inhibition,of |
R1216 | T4171 | T4170 | arg1Of | inhibition,crosstalk |
R1217 | T4096 | T4102 | arg1Of | Studies,shown |
R1218 | T4173 | T4172 | arg2Of | opposing,by |
R1219 | T4176 | T4173 | arg2Of | pathways,opposing |
R1220 | T4176 | T4174 | arg1Of | pathways,cytokine |
R1221 | T4176 | T4175 | arg1Of | pathways,signaling |
R1222 | T4100 | T4097 | arg2Of | mice,of |
R1223 | T4179 | T4163 | arg2Of | clarified,but |
R1224 | T4179 | T4177 | arg2Of | clarified,have |
R1225 | T4179 | T4178 | arg2Of | clarified,been |
R1226 | T4179 | T4180 | arg1Of | clarified,[ |
R1227 | T4181 | T4180 | arg2Of | 7,[ |
R1228 | T4100 | T4098 | arg1Of | mice,cell-type-specific |
R1229 | T4182 | T4180 | arg3Of | ],[ |
R1230 | T4100 | T4099 | arg1Of | mice,STAT3-deficient |
R1231 | T4102 | T4101 | arg2Of | shown,have |
R1232 | T4184 | T4183 | arg1Of | studies,Recent |
R1233 | T4184 | T4185 | arg1Of | studies,indicate |
R1234 | T4105 | T4104 | arg1Of | activation,STAT3 |
R1235 | T4187 | T4188 | arg1Of | SOCS3,plays |
R1236 | T4187 | T4193 | arg1Of | SOCS3,regulating |
R1237 | T4188 | T4185 | arg2Of | plays,indicate |
R1238 | T4188 | T4186 | arg1Of | plays,that |
R1239 | T4188 | T4192 | arg1Of | plays,in |
R1240 | T4188 | T4201 | arg1Of | plays,"," |
R1241 | T4188 | T4202 | arg1Of | plays,by |
R1242 | T4105 | T4106 | arg1Of | activation,is |
R1243 | T4105 | T4107 | arg1Of | activation,essential |
R1244 | T4191 | T4188 | arg2Of | role,plays |
R1245 | T4191 | T4189 | arg1Of | role,a |
R1246 | T4191 | T4190 | arg1Of | role,key |
R1247 | T4105 | T4121 | arg1Of | activation,is |
R1248 | T4193 | T4192 | arg2Of | regulating,in |
R1249 | T4105 | T4122 | arg1Of | activation,responsible |
R1250 | T4196 | T4193 | arg2Of | action,regulating |
R1251 | T4196 | T4194 | arg1Of | action,the |
R1252 | T4196 | T4195 | arg1Of | action,divergent |
R1253 | T4196 | T4197 | arg1Of | action,of |
R1254 | T4106 | T4120 | arg1Of | is,but |
R1255 | T4198 | T4199 | arg1Of | IL-10,and |
R1256 | T4199 | T4197 | arg2Of | and,of |
R1257 | T4200 | T4199 | arg2Of | IL-6,and |
R1258 | T4107 | T4106 | arg2Of | essential,is |
R1259 | T4107 | T4108 | arg1Of | essential,for |
R1260 | T4204 | T4202 | arg2Of | blocking,by |
R1261 | T4204 | T4203 | arg1Of | blocking,specifically |
R1262 | T4111 | T4108 | arg2Of | reactions,for |
R1263 | T4206 | T4205 | arg1Of | activation,STAT3 |
R1264 | T4206 | T4207 | arg2Of | activation,induced |
R1265 | T4206 | T4210 | arg1Of | activation,but |
R1266 | T4209 | T4207 | arg1Of | IL-6,induced |
R1267 | T4209 | T4208 | arg2Of | IL-6,by |
R1268 | T4210 | T4204 | arg2Of | but,blocking |
R1269 | T4210 | T4211 | arg1Of | but,not |
R1270 | T4212 | T4210 | arg2Of | that,but |
R1271 | T4212 | T4213 | arg2Of | that,induced |
R1272 | T4213 | T4216 | arg1Of | induced,[ |
R1273 | T4215 | T4213 | arg1Of | IL-10,induced |
R1274 | T4215 | T4214 | arg2Of | IL-10,by |
R1275 | T4111 | T4109 | arg1Of | reactions,IL-10-mediated |
R1276 | T4217 | T4216 | arg2Of | "8,9",[ |
R1277 | T4111 | T4110 | arg1Of | reactions,anti-inflammatory |
R1278 | T4218 | T4216 | arg3Of | ],[ |
R1279 | T4111 | T4112 | arg1Of | reactions,in |
R1280 | T4113 | T4114 | arg1Of | macrophages,and |
R1289 | T4114 | T4112 | arg2Of | and,in |
R1292 | T4114 | T4116 | arg1Of | and,[ |
R1294 | T4115 | T4114 | arg2Of | neutrophils,and |
R1299 | T4117 | T4116 | arg2Of | 5,[ |
R1303 | T4118 | T4116 | arg3Of | ],[ |
R1309 | T4120 | T4102 | arg2Of | but,shown |
R1311 | T4120 | T4103 | arg1Of | but,that |
R1312 | T4120 | T4119 | arg1Of | but,"," |
R1314 | T4120 | T4131 | arg1Of | but,[ |
R1316 | T4121 | T4120 | arg2Of | is,but |
R1321 | T4122 | T4121 | arg2Of | responsible,is |
R1325 | T4122 | T4123 | arg1Of | responsible,for |
R1328 | T4125 | T4123 | arg2Of | prevention,for |
R1332 | T4125 | T4124 | arg1Of | prevention,IL-6-mediated |
R1333 | T4125 | T4126 | arg1Of | prevention,of |
R1340 | T4125 | T4128 | arg1Of | prevention,in |
R1341 | T4127 | T4126 | arg2Of | apoptosis,of |
R1346 | T4130 | T4128 | arg2Of | cells,in |
R1348 | T4130 | T4129 | arg1Of | cells,T |
R1350 | T4132 | T4131 | arg2Of | 6,[ |
R1354 | T4133 | T4131 | arg3Of | ],[ |
R1359 | T4135 | T4134 | arg1Of | suppressor,The |
R1362 | T4135 | T4136 | arg1Of | suppressor,of |
R1374 | T4135 | T4143 | arg1Of | suppressor,have |
R1375 | T4135 | T4144 | arg1Of | suppressor,been |
R1376 | T4135 | T4145 | arg2Of | suppressor,identified |
R1377 | T4140 | T4139 | arg2Of | SOCS,( |
R1391 | T4141 | T4139 | arg3Of | ),( |
R1395 | T4142 | T4136 | arg2Of | proteins,of |
R1398 | T4142 | T4137 | arg1Of | proteins,cytokine |
R1400 | T4142 | T4138 | arg1Of | proteins,signaling |
R1403 | T4142 | T4139 | arg1Of | proteins,( |
R1404 | T4145 | T4143 | arg2Of | identified,have |
R1413 | T4145 | T4144 | arg2Of | identified,been |
R1415 | T4145 | T4146 | arg1Of | identified,as |
R1417 | T4145 | T4163 | arg1Of | identified,but |
R1029 | T3940 | T3941 | arg1Of | IL-10,is |
R1030 | T3944 | T3941 | arg2Of | cytokine,is |
R1031 | T3944 | T3942 | arg1Of | cytokine,a |
R1032 | T3944 | T3943 | arg1Of | cytokine,key |
R1033 | T3944 | T3945 | arg1Of | cytokine,in |
R1034 | T3946 | T3945 | arg2Of | regulating,in |
R1035 | T3946 | T3949 | arg1Of | regulating,"," |
R1036 | T3946 | T3951 | arg1Of | regulating,by |
R1037 | T3948 | T3946 | arg2Of | responses,regulating |
R1038 | T3948 | T3947 | arg1Of | responses,inflammatory |
R1039 | T3951 | T3950 | arg1Of | by,mainly |
R1046 | T3952 | T3951 | arg2Of | inhibiting,by |
R1048 | T3954 | T3955 | arg1Of | production,and |
R1049 | T3955 | T3952 | arg2Of | and,inhibiting |
R1050 | T3955 | T3953 | arg1Of | and,the |
R1051 | T3955 | T3957 | arg1Of | and,of |
R1053 | T3956 | T3955 | arg2Of | function,and |
R1054 | T3959 | T3957 | arg2Of | cytokines,of |
R1055 | T3959 | T3958 | arg1Of | cytokines,proinflammatory |
R1057 | T3960 | T3961 | arg1Of | IL-10,binds |
R1058 | T3961 | T3962 | arg1Of | binds,to |
R1060 | T3965 | T3964 | arg1Of | receptor,IL-10 |
R1061 | T3965 | T3966 | arg1Of | receptor,( |
R1062 | T3967 | T3966 | arg2Of | IL-10R,( |
R1063 | T3968 | T3966 | arg3Of | ),( |
R1065 | T3969 | T3962 | arg2Of | complex,to |
R1066 | T3969 | T3963 | arg1Of | complex,the |
R1067 | T3969 | T3965 | arg1Of | complex,receptor |
R1068 | T3969 | T3970 | arg1Of | complex,that |
R1069 | T3969 | T3971 | arg1Of | complex,is |
R1070 | T3969 | T3972 | arg2Of | complex,composed |
R1071 | T3972 | T3971 | arg2Of | composed,is |
R1072 | T3972 | T3973 | arg1Of | composed,of |
R1076 | T3975 | T3973 | arg2Of | subunits,of |
R1077 | T3975 | T3974 | arg1Of | subunits,two |
R1078 | T3975 | T3976 | arg1Of | subunits,"," |
R1094 | T3987 | T3976 | arg2Of | and,"," |
bionlp-st-ge-2016-coref
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3458 | 315-328 | Antecedent | denotes | type 2 IL-10R |
T3457 | 263-276 | Antecedent | denotes | type 1 IL-10R |
T3456 | 212-224 | Anaphor | denotes | two subunits |
R942 | T3456 | T3457 | boundBy | two subunits,type 1 IL-10R |
R943 | T3456 | T3458 | boundBy | two subunits,type 2 IL-10R |
bionlp-st-ge-2016-test-proteins
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3486 | 1171-1175 | Protein | denotes | IL-6 |
T3485 | 1069-1074 | Protein | denotes | IL-10 |
T3484 | 1035-1040 | Protein | denotes | STAT3 |
T3483 | 998-1003 | Protein | denotes | STAT3 |
T3482 | 924-928 | Protein | denotes | IL-6 |
T3481 | 888-893 | Protein | denotes | IL-10 |
T3480 | 856-861 | Protein | denotes | STAT3 |
T3479 | 723-728 | Protein | denotes | STAT3 |
T3478 | 713-718 | Protein | denotes | STAT1 |
T3477 | 680-685 | Protein | denotes | STAT1 |
T3476 | 618-675 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
T3475 | 526-531 | Protein | denotes | IL-10 |
T3474 | 493-506 | Protein | denotes | type 2 IL-10R |
T3473 | 481-488 | Protein | denotes | IL-10R1 |
T3472 | 434-438 | Protein | denotes | Tyk2 |
T3471 | 425-429 | Protein | denotes | Jak1 |
T3470 | 363-369 | Protein | denotes | IL-10R |
T3469 | 353-358 | Protein | denotes | IL-10 |
T3468 | 315-328 | Protein | denotes | type 2 IL-10R |
T3467 | 278-285 | Protein | denotes | IL-10R1 |
T3466 | 263-276 | Protein | denotes | type 1 IL-10R |
T3465 | 176-182 | Protein | denotes | IL-10R |
T3464 | 160-174 | Protein | denotes | IL-10 receptor |
T3463 | 141-146 | Protein | denotes | IL-10 |
T3462 | 1-5 | Protein | denotes | L-10 |
T3492 | 1708-1713 | Protein | denotes | IL-10 |
T3491 | 1679-1683 | Protein | denotes | IL-6 |
T3490 | 1651-1656 | Protein | denotes | STAT3 |
T3489 | 1620-1624 | Protein | denotes | IL-6 |
T3488 | 1610-1615 | Protein | denotes | IL-10 |
T3487 | 1549-1554 | Protein | denotes | SOCS3 |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3701 | 1620-1624 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
T3700 | 1171-1175 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
T3699 | 924-928 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
T3697 | 1651-1656 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
T3696 | 1035-1040 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
T3695 | 998-1003 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
T3694 | 856-861 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
T3693 | 723-728 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
T3692 | 522-528 | http://www.uniprot.org/uniprot/P60568 | denotes | 2]. IL |
T3691 | 498-502 | http://www.uniprot.org/uniprot/P60568 | denotes | 2 IL |
T3690 | 320-324 | http://www.uniprot.org/uniprot/P60568 | denotes | 2 IL |
T3683 | 1708-1713 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
T3682 | 1610-1615 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
T3681 | 1069-1074 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
T3680 | 888-893 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
T3679 | 526-531 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
T3678 | 353-358 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
T3677 | 160-165 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
T3676 | 141-146 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
T3675 | 0-5 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
T3702 | 1679-1683 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3289 | 1476-1494 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathways |
T3288 | 1467-1494 | http://purl.obolibrary.org/obo/GO_0019221 | denotes | cytokine signaling pathways |
T3287 | 1329-1346 | http://purl.obolibrary.org/obo/GO_0033673 | denotes | kinase inhibitors |
T3286 | 1199-1208 | http://purl.obolibrary.org/obo/GO_0097194 | denotes | apoptosis |
T3285 | 1199-1208 | http://purl.obolibrary.org/obo/GO_0006915 | denotes | apoptosis |
T3273 | 696-711 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T3272 | 549-564 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T3271 | 540-579 | http://purl.obolibrary.org/obo/GO_0050731 | denotes | tyrosine phosphorylation and activation |
T3270 | 1325-1328 | http://purl.obolibrary.org/obo/GO_0004713 | denotes | JAK |
T3269 | 396-399 | http://purl.obolibrary.org/obo/GO_0004713 | denotes | JAK |
T3268 | 166-178 | http://purl.obolibrary.org/obo/GO_0004896 | denotes | receptor (IL |
T3267 | 500-506 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3266 | 363-369 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3265 | 322-328 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3264 | 270-276 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3263 | 176-182 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3262 | 160-174 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10 receptor |
T3259 | 38-60 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory responses |
T3279 | 618-624 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signal |
T3278 | 827-840 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T3277 | 653-666 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T3276 | 594-609 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcriptional |
T3275 | 549-579 | http://purl.obolibrary.org/obo/GO_0042327 | denotes | phosphorylation and activation |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3580 | 979-983 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T3579 | 800-807 | http://purl.obolibrary.org/obo/GO_0005634 | denotes | nucleus |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3574 | 1679-1683 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
T3573 | 1620-1624 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
T3572 | 1171-1175 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
T3571 | 924-928 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
T3570 | 1325-1328 | http://purl.obolibrary.org/obo/GO_0004713 | denotes | JAK |
T3569 | 396-399 | http://purl.obolibrary.org/obo/GO_0004713 | denotes | JAK |
T3568 | 522-528 | http://purl.obolibrary.org/obo/GO_0005134 | denotes | 2]. IL |
T3567 | 498-502 | http://purl.obolibrary.org/obo/GO_0005134 | denotes | 2 IL |
T3566 | 320-324 | http://purl.obolibrary.org/obo/GO_0005134 | denotes | 2 IL |
T3562 | 268-272 | http://purl.obolibrary.org/obo/GO_0005149 | denotes | 1 IL |
T3560 | 245-252 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T3559 | 238-244 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | ligand |
T3558 | 166-178 | http://purl.obolibrary.org/obo/GO_0004896 | denotes | receptor (IL |
T3557 | 500-506 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3556 | 363-369 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3555 | 322-328 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3554 | 270-276 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3553 | 176-182 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
T3552 | 160-174 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10 receptor |
T3545 | 1708-1713 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T3544 | 1610-1615 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T3543 | 1069-1074 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T3542 | 888-893 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T3541 | 526-531 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T3540 | 353-358 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T3539 | 160-165 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T3538 | 141-146 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T3537 | 0-5 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3238 | 691-841 | Sentence | denotes | Upon phosphorylation, STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription. |
T3237 | 526-690 | Sentence | denotes | IL-10 induces tyrosine phosphorylation and activation of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 and STAT1 [3]. |
T3236 | 334-525 | Sentence | denotes | The interaction of IL-10 and IL-10R engages the Janus kinase (JAK) family tyrosine kinases Jak1 and Tyk2, which are constitutively associated with IL-10R1 and type 2 IL-10R, respectively [2]. |
T3235 | 141-333 | Sentence | denotes | IL-10 binds to the IL-10 receptor (IL-10R) complex that is composed of two subunits, the primary ligand-binding component type 1 IL-10R (IL-10R1) and the accessory component type 2 IL-10R [1]. |
T3234 | 0-140 | Sentence | denotes | IL-10 is a key cytokine in regulating inflammatory responses, mainly by inhibiting the production and function of proinflammatory cytokines. |
T3242 | 1520-1720 | Sentence | denotes | Recent studies indicate that SOCS3 plays a key role in regulating the divergent action of IL-10 and IL-6, by specifically blocking STAT3 activation induced by IL-6 but not that induced by IL-10 [8,9]. |
T3241 | 1225-1519 | Sentence | denotes | The suppressor of cytokine signaling (SOCS) proteins have been identified as a family of endogenous JAK kinase inhibitors that can act in classic feedback inhibition loops, but their roles as the mediators of crosstalk inhibition by opposing cytokine signaling pathways have been clarified [7]. |
T3240 | 968-1224 | Sentence | denotes | Studies of cell-type-specific STAT3-deficient mice have shown that STAT3 activation is essential for IL-10-mediated anti-inflammatory reactions in macrophages and neutrophils [5], but is responsible for IL-6-mediated prevention of apoptosis in T cells [6]. |
T3239 | 842-967 | Sentence | denotes | Intriguingly, STAT3 is indispensable for both IL-10-derived anti-inflammatory and IL-6-derived proinflammatory responses [4]. |
T11 | 0-140 | Sentence | denotes | IL-10 is a key cytokine in regulating inflammatory responses, mainly by inhibiting the production and function of proinflammatory cytokines. |
T12 | 141-333 | Sentence | denotes | IL-10 binds to the IL-10 receptor (IL-10R) complex that is composed of two subunits, the primary ligand-binding component type 1 IL-10R (IL-10R1) and the accessory component type 2 IL-10R [1]. |
T13 | 334-525 | Sentence | denotes | The interaction of IL-10 and IL-10R engages the Janus kinase (JAK) family tyrosine kinases Jak1 and Tyk2, which are constitutively associated with IL-10R1 and type 2 IL-10R, respectively [2]. |
T14 | 526-690 | Sentence | denotes | IL-10 induces tyrosine phosphorylation and activation of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 and STAT1 [3]. |
T15 | 691-841 | Sentence | denotes | Upon phosphorylation, STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription. |
T16 | 842-967 | Sentence | denotes | Intriguingly, STAT3 is indispensable for both IL-10-derived anti-inflammatory and IL-6-derived proinflammatory responses [4]. |
T17 | 968-1224 | Sentence | denotes | Studies of cell-type-specific STAT3-deficient mice have shown that STAT3 activation is essential for IL-10-mediated anti-inflammatory reactions in macrophages and neutrophils [5], but is responsible for IL-6-mediated prevention of apoptosis in T cells [6]. |
T18 | 1225-1519 | Sentence | denotes | The suppressor of cytokine signaling (SOCS) proteins have been identified as a family of endogenous JAK kinase inhibitors that can act in classic feedback inhibition loops, but their roles as the mediators of crosstalk inhibition by opposing cytokine signaling pathways have been clarified [7]. |
T19 | 1520-1720 | Sentence | denotes | Recent studies indicate that SOCS3 plays a key role in regulating the divergent action of IL-10 and IL-6, by specifically blocking STAT3 activation induced by IL-6 but not that induced by IL-10 [8,9]. |
simple1
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3895 | 1708-1713 | Protein | denotes | IL-10 |
T3894 | 1679-1683 | Protein | denotes | IL-6 |
T3893 | 1651-1656 | Protein | denotes | STAT3 |
T3892 | 1620-1624 | Protein | denotes | IL-6 |
T3891 | 1610-1615 | Protein | denotes | IL-10 |
T3890 | 1549-1554 | Protein | denotes | SOCS3 |
T3889 | 1171-1175 | Protein | denotes | IL-6 |
T3888 | 1069-1074 | Protein | denotes | IL-10 |
T3887 | 1035-1040 | Protein | denotes | STAT3 |
T3886 | 998-1003 | Protein | denotes | STAT3 |
T3885 | 924-928 | Protein | denotes | IL-6 |
T3884 | 888-893 | Protein | denotes | IL-10 |
T3883 | 856-861 | Protein | denotes | STAT3 |
T3882 | 723-728 | Protein | denotes | STAT3 |
T3881 | 713-718 | Protein | denotes | STAT1 |
T3880 | 680-685 | Protein | denotes | STAT1 |
T3879 | 618-675 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
T3878 | 526-531 | Protein | denotes | IL-10 |
T3877 | 493-506 | Protein | denotes | type 2 IL-10R |
T3876 | 481-488 | Protein | denotes | IL-10R1 |
T3875 | 434-438 | Protein | denotes | Tyk2 |
T3874 | 425-429 | Protein | denotes | Jak1 |
T3873 | 363-369 | Protein | denotes | IL-10R |
T3872 | 353-358 | Protein | denotes | IL-10 |
T3871 | 315-328 | Protein | denotes | type 2 IL-10R |
T3870 | 278-285 | Protein | denotes | IL-10R1 |
T3869 | 263-276 | Protein | denotes | type 1 IL-10R |
T3868 | 176-182 | Protein | denotes | IL-10R |
T3867 | 160-174 | Protein | denotes | IL-10 receptor |
T3866 | 141-146 | Protein | denotes | IL-10 |
T3865 | 1-5 | Protein | denotes | L-10 |
BioNLP16_DUT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6464 | 1697-1704 | Positive_regulation | denotes | induced |
T6463 | 1642-1650 | Negative_regulation | denotes | blocking |
T6462 | 1668-1675 | Positive_regulation | denotes | induced |
T6461 | 1657-1667 | Positive_regulation | denotes | activation |
T6460 | 1041-1051 | Positive_regulation | denotes | activation |
T6459 | 1004-1013 | Negative_regulation | denotes | deficient |
T6458 | 779-790 | Localization | denotes | translocate |
T6457 | 696-711 | Phosphorylation | denotes | phosphorylation |
T6456 | 549-564 | Phosphorylation | denotes | phosphorylation |
T6455 | 532-539 | Positive_regulation | denotes | induces |
T6454 | 569-579 | Positive_regulation | denotes | activation |
T6453 | 465-475 | Binding | denotes | associated |
T6452 | 338-349 | Binding | denotes | interaction |
T6451 | 370-377 | Binding | denotes | engages |
T6450 | 147-152 | Binding | denotes | binds |
T6405 | 1708-1713 | Protein | denotes | IL-10 |
T6404 | 1679-1683 | Protein | denotes | IL-6 |
T6403 | 1651-1656 | Protein | denotes | STAT3 |
T6402 | 1620-1624 | Protein | denotes | IL-6 |
T6401 | 1610-1615 | Protein | denotes | IL-10 |
T6400 | 1549-1554 | Protein | denotes | SOCS3 |
T6399 | 1171-1175 | Protein | denotes | IL-6 |
T6398 | 1069-1074 | Protein | denotes | IL-10 |
T6397 | 1035-1040 | Protein | denotes | STAT3 |
T6396 | 998-1003 | Protein | denotes | STAT3 |
T6395 | 924-928 | Protein | denotes | IL-6 |
T6394 | 888-893 | Protein | denotes | IL-10 |
T6393 | 856-861 | Protein | denotes | STAT3 |
T6392 | 723-728 | Protein | denotes | STAT3 |
T6391 | 713-718 | Protein | denotes | STAT1 |
T6390 | 680-685 | Protein | denotes | STAT1 |
T6389 | 618-675 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
T6388 | 526-531 | Protein | denotes | IL-10 |
T6387 | 363-369 | Protein | denotes | IL-10R |
T6386 | 353-358 | Protein | denotes | IL-10 |
T6385 | 493-506 | Protein | denotes | type 2 IL-10R |
T6384 | 481-488 | Protein | denotes | IL-10R1 |
T6383 | 434-438 | Protein | denotes | Tyk2 |
T6382 | 425-429 | Protein | denotes | Jak1 |
T6381 | 315-328 | Protein | denotes | type 2 IL-10R |
T6380 | 278-285 | Protein | denotes | IL-10R1 |
T6379 | 263-276 | Protein | denotes | type 1 IL-10R |
T6378 | 176-182 | Protein | denotes | IL-10R |
T6377 | 160-174 | Protein | denotes | IL-10 receptor |
T6376 | 141-146 | Protein | denotes | IL-10 |
T6375 | 1-5 | Protein | denotes | L-10 |
R3137 | T6376 | T6450 | themeOf | IL-10,binds |
R3138 | T6376 | T6450 | themeOf | IL-10,binds |
R3139 | T6377 | T6450 | themeOf | IL-10 receptor,binds |
R3140 | T6378 | T6450 | themeOf | IL-10R,binds |
R3142 | T6382 | T6451 | themeOf | Jak1,engages |
R3143 | T6382 | T6453 | themeOf | Jak1,associated |
R3145 | T6383 | T6451 | themeOf | Tyk2,engages |
R3146 | T6383 | T6453 | themeOf | Tyk2,associated |
R3148 | T6384 | T6453 | themeOf | IL-10R1,associated |
R3150 | T6384 | T6453 | themeOf | IL-10R1,associated |
R3151 | T6386 | T6452 | themeOf | IL-10,interaction |
R3152 | T6387 | T6452 | themeOf | IL-10R,interaction |
R3155 | T6389 | T6456 | themeOf | signal transducer and activator of transcription (STAT) 3,phosphorylation |
R3156 | T6389 | T6454 | themeOf | signal transducer and activator of transcription (STAT) 3,activation |
R3158 | T6390 | T6456 | themeOf | STAT1,phosphorylation |
R3159 | T6390 | T6454 | themeOf | STAT1,activation |
R3161 | T6391 | T6458 | themeOf | STAT1,translocate |
R3162 | T6391 | T6457 | themeOf | STAT1,phosphorylation |
R3163 | T6392 | T6458 | themeOf | STAT3,translocate |
R3164 | T6396 | T6459 | themeOf | STAT3,deficient |
R3165 | T6397 | T6460 | themeOf | STAT3,activation |
R3167 | T6400 | T6464 | themeOf | SOCS3,induced |
R3170 | T6403 | T6461 | themeOf | STAT3,activation |
R3171 | T6403 | T6462 | themeOf | STAT3,induced |
R3185 | T6456 | T6455 | themeOf | phosphorylation,induces |
R3186 | T6456 | T6455 | themeOf | phosphorylation,induces |
R3187 | T6461 | T6463 | themeOf | activation,blocking |
R3188 | T6461 | T6462 | themeOf | activation,induced |
BioNLP16_Messiy
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4904 | 1668-1675 | Positive_regulation | denotes | induced |
T4903 | 1642-1650 | Negative_regulation | denotes | blocking |
T4902 | 1657-1667 | Positive_regulation | denotes | activation |
T4901 | 1697-1704 | Positive_regulation | denotes | induced |
T4900 | 1055-1064 | Positive_regulation | denotes | essential |
T4899 | 1041-1051 | Positive_regulation | denotes | activation |
T4898 | 1004-1013 | Negative_regulation | denotes | deficient |
T4897 | 1155-1166 | Regulation | denotes | responsible |
T4896 | 779-790 | Localization | denotes | translocate |
T4895 | 532-539 | Positive_regulation | denotes | induces |
T4894 | 549-564 | Phosphorylation | denotes | phosphorylation |
T4893 | 569-579 | Positive_regulation | denotes | activation |
T4892 | 465-475 | Binding | denotes | associated |
T4891 | 370-377 | Binding | denotes | engages |
T4890 | 338-349 | Binding | denotes | interaction |
T4889 | 147-152 | Binding | denotes | binds |
T4888 | 238-252 | Binding | denotes | ligand-binding |
T4843 | 1708-1713 | Protein | denotes | IL-10 |
T4842 | 1679-1683 | Protein | denotes | IL-6 |
T4841 | 1651-1656 | Protein | denotes | STAT3 |
T4840 | 1620-1624 | Protein | denotes | IL-6 |
T4839 | 1610-1615 | Protein | denotes | IL-10 |
T4838 | 1549-1554 | Protein | denotes | SOCS3 |
T4837 | 1171-1175 | Protein | denotes | IL-6 |
T4836 | 1069-1074 | Protein | denotes | IL-10 |
T4835 | 1035-1040 | Protein | denotes | STAT3 |
T4834 | 998-1003 | Protein | denotes | STAT3 |
T4833 | 924-928 | Protein | denotes | IL-6 |
T4832 | 888-893 | Protein | denotes | IL-10 |
T4831 | 856-861 | Protein | denotes | STAT3 |
T4830 | 723-728 | Protein | denotes | STAT3 |
T4829 | 713-718 | Protein | denotes | STAT1 |
T4828 | 680-685 | Protein | denotes | STAT1 |
T4827 | 618-675 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
T4826 | 526-531 | Protein | denotes | IL-10 |
T4825 | 363-369 | Protein | denotes | IL-10R |
T4824 | 353-358 | Protein | denotes | IL-10 |
T4823 | 493-506 | Protein | denotes | type 2 IL-10R |
T4822 | 481-488 | Protein | denotes | IL-10R1 |
T4821 | 434-438 | Protein | denotes | Tyk2 |
T4820 | 425-429 | Protein | denotes | Jak1 |
T4819 | 315-328 | Protein | denotes | type 2 IL-10R |
T4818 | 278-285 | Protein | denotes | IL-10R1 |
T4817 | 263-276 | Protein | denotes | type 1 IL-10R |
T4816 | 176-182 | Protein | denotes | IL-10R |
T4815 | 160-174 | Protein | denotes | IL-10 receptor |
T4814 | 141-146 | Protein | denotes | IL-10 |
T4813 | 1-5 | Protein | denotes | L-10 |
R1849 | T4814 | T4889 | themeOf | IL-10,binds |
R1851 | T4814 | T4889 | themeOf | IL-10,binds |
R1853 | T4815 | T4889 | themeOf | IL-10 receptor,binds |
R1854 | T4816 | T4889 | themeOf | IL-10R,binds |
R1858 | T4818 | T4888 | themeOf | IL-10R1,ligand-binding |
R1862 | T4820 | T4891 | themeOf | Jak1,engages |
R1866 | T4821 | T4891 | themeOf | Tyk2,engages |
R1867 | T4821 | T4892 | themeOf | Tyk2,associated |
R1869 | T4822 | T4892 | themeOf | IL-10R1,associated |
R1871 | T4824 | T4890 | themeOf | IL-10,interaction |
R1872 | T4825 | T4890 | themeOf | IL-10R,interaction |
R1874 | T4826 | T4895 | causeOf | IL-10,induces |
R1878 | T4827 | T4894 | themeOf | signal transducer and activator of transcription (STAT) 3,phosphorylation |
R1880 | T4827 | T4893 | themeOf | signal transducer and activator of transcription (STAT) 3,activation |
R1881 | T4828 | T4895 | themeOf | STAT1,induces |
R1882 | T4828 | T4894 | themeOf | STAT1,phosphorylation |
R1884 | T4828 | T4893 | themeOf | STAT1,activation |
R1887 | T4829 | T4896 | themeOf | STAT1,translocate |
R1888 | T4830 | T4896 | themeOf | STAT3,translocate |
R1892 | T4834 | T4898 | themeOf | STAT3,deficient |
R1894 | T4835 | T4899 | themeOf | STAT3,activation |
R1896 | T4838 | T4903 | causeOf | SOCS3,blocking |
R1899 | T4838 | T4901 | causeOf | SOCS3,induced |
R1902 | T4841 | T4902 | themeOf | STAT3,activation |
R1904 | T4841 | T4904 | themeOf | STAT3,induced |
R1907 | T4842 | T4904 | causeOf | IL-6,induced |
R1908 | T4842 | T4904 | causeOf | IL-6,induced |
R1911 | T4843 | T4901 | themeOf | IL-10,induced |
R1968 | T4899 | T4900 | themeOf | activation,essential |
R1971 | T4899 | T4897 | themeOf | activation,responsible |
R1973 | T4902 | T4903 | themeOf | activation,blocking |
R1974 | T4902 | T4904 | themeOf | activation,induced |
DLUT931
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5916 | 1642-1650 | Negative_regulation | denotes | blocking |
T5915 | 1668-1675 | Positive_regulation | denotes | induced |
T5914 | 1657-1667 | Positive_regulation | denotes | activation |
T5913 | 1575-1585 | Regulation | denotes | regulating |
T5912 | 1075-1083 | Positive_regulation | denotes | mediated |
T5911 | 1041-1051 | Positive_regulation | denotes | activation |
T5910 | 1004-1013 | Negative_regulation | denotes | deficient |
T5909 | 813-821 | Regulation | denotes | modulate |
T5908 | 779-790 | Localization | denotes | translocate |
T5907 | 696-711 | Phosphorylation | denotes | phosphorylation |
T5906 | 532-539 | Positive_regulation | denotes | induces |
T5905 | 569-579 | Positive_regulation | denotes | activation |
T5904 | 549-564 | Phosphorylation | denotes | phosphorylation |
T5903 | 370-377 | Binding | denotes | engages |
T5902 | 338-349 | Binding | denotes | interaction |
T5901 | 238-252 | Binding | denotes | ligand-binding |
T5900 | 147-152 | Binding | denotes | binds |
T5855 | 1708-1713 | Protein | denotes | IL-10 |
T5854 | 1679-1683 | Protein | denotes | IL-6 |
T5853 | 1651-1656 | Protein | denotes | STAT3 |
T5852 | 1620-1624 | Protein | denotes | IL-6 |
T5851 | 1610-1615 | Protein | denotes | IL-10 |
T5850 | 1549-1554 | Protein | denotes | SOCS3 |
T5849 | 1171-1175 | Protein | denotes | IL-6 |
T5848 | 1069-1074 | Protein | denotes | IL-10 |
T5847 | 1035-1040 | Protein | denotes | STAT3 |
T5846 | 998-1003 | Protein | denotes | STAT3 |
T5845 | 924-928 | Protein | denotes | IL-6 |
T5844 | 888-893 | Protein | denotes | IL-10 |
T5843 | 856-861 | Protein | denotes | STAT3 |
T5842 | 723-728 | Protein | denotes | STAT3 |
T5841 | 713-718 | Protein | denotes | STAT1 |
T5840 | 680-685 | Protein | denotes | STAT1 |
T5839 | 618-675 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
T5838 | 526-531 | Protein | denotes | IL-10 |
T5837 | 363-369 | Protein | denotes | IL-10R |
T5836 | 353-358 | Protein | denotes | IL-10 |
T5835 | 493-506 | Protein | denotes | type 2 IL-10R |
T5834 | 481-488 | Protein | denotes | IL-10R1 |
T5833 | 434-438 | Protein | denotes | Tyk2 |
T5832 | 425-429 | Protein | denotes | Jak1 |
T5831 | 315-328 | Protein | denotes | type 2 IL-10R |
T5830 | 278-285 | Protein | denotes | IL-10R1 |
T5829 | 263-276 | Protein | denotes | type 1 IL-10R |
T5828 | 176-182 | Protein | denotes | IL-10R |
T5827 | 160-174 | Protein | denotes | IL-10 receptor |
T5826 | 141-146 | Protein | denotes | IL-10 |
T5825 | 1-5 | Protein | denotes | L-10 |
R2886 | T5826 | T5900 | themeOf | IL-10,binds |
R2888 | T5826 | T5900 | themeOf | IL-10,binds |
R2890 | T5827 | T5900 | themeOf | IL-10 receptor,binds |
R2891 | T5828 | T5900 | themeOf | IL-10R,binds |
R2892 | T5829 | T5901 | themeOf | type 1 IL-10R,ligand-binding |
R2893 | T5829 | T5901 | themeOf | type 1 IL-10R,ligand-binding |
R2895 | T5830 | T5901 | themeOf | IL-10R1,ligand-binding |
R2896 | T5830 | T5901 | themeOf | IL-10R1,ligand-binding |
R2897 | T5831 | T5901 | themeOf | type 2 IL-10R,ligand-binding |
R2898 | T5831 | T5901 | themeOf | type 2 IL-10R,ligand-binding |
R2899 | T5832 | T5903 | themeOf | Jak1,engages |
R2901 | T5833 | T5903 | themeOf | Tyk2,engages |
R2902 | T5833 | T5903 | themeOf | Tyk2,engages |
R2903 | T5836 | T5902 | themeOf | IL-10,interaction |
R2904 | T5837 | T5902 | themeOf | IL-10R,interaction |
R2906 | T5838 | T5906 | causeOf | IL-10,induces |
R2907 | T5838 | T5906 | causeOf | IL-10,induces |
R2908 | T5838 | T5906 | causeOf | IL-10,induces |
R2909 | T5838 | T5906 | causeOf | IL-10,induces |
R2910 | T5839 | T5904 | themeOf | signal transducer and activator of transcription (STAT) 3,phosphorylation |
R2911 | T5840 | T5904 | themeOf | STAT1,phosphorylation |
R2912 | T5841 | T5907 | themeOf | STAT1,phosphorylation |
R2913 | T5841 | T5908 | themeOf | STAT1,translocate |
R2914 | T5841 | T5909 | themeOf | STAT1,modulate |
R2915 | T5842 | T5907 | themeOf | STAT3,phosphorylation |
R2916 | T5842 | T5908 | themeOf | STAT3,translocate |
R2917 | T5842 | T5909 | themeOf | STAT3,modulate |
R2919 | T5846 | T5910 | themeOf | STAT3,deficient |
R2920 | T5847 | T5911 | themeOf | STAT3,activation |
R2921 | T5848 | T5912 | themeOf | IL-10,mediated |
R2922 | T5850 | T5916 | causeOf | SOCS3,blocking |
R2923 | T5851 | T5913 | themeOf | IL-10,regulating |
R2924 | T5852 | T5913 | themeOf | IL-6,regulating |
R2925 | T5853 | T5914 | themeOf | STAT3,activation |
R2927 | T5854 | T5915 | causeOf | IL-6,induced |
R2947 | T5904 | T5905 | themeOf | phosphorylation,activation |
R2948 | T5904 | T5906 | themeOf | phosphorylation,induces |
R2949 | T5904 | T5905 | themeOf | phosphorylation,activation |
R2950 | T5904 | T5906 | themeOf | phosphorylation,induces |
R2951 | T5905 | T5906 | themeOf | activation,induces |
R2952 | T5905 | T5906 | themeOf | activation,induces |
R2953 | T5907 | T5909 | themeOf | phosphorylation,modulate |
R2954 | T5907 | T5909 | themeOf | phosphorylation,modulate |
R2957 | T5914 | T5915 | themeOf | activation,induced |
R2958 | T5914 | T5916 | themeOf | activation,blocking |
R2959 | T5915 | T5914 | themeOf | induced,activation |
bionlp-st-ge-2016-test-ihmc
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6250 | 713-718 | Protein | denotes | STAT1 |
T6249 | 1620-1624 | Protein | denotes | IL-6 |
T6246 | 378-429 | Protein | denotes | the Janus kinase (JAK) family tyrosine kinases Jak1 |
T6355 | 440-506 | Binding | denotes | which are constitutively associated with IL-10R1 and type 2 IL-10R |
T6354 | 334-369 | Binding | denotes | The interaction of IL-10 and IL-10R |
T6353 | 1651-1713 | Positive_regulation | denotes | STAT3 activation induced by IL-6 but not that induced by IL-10 |
T6349 | 226-286 | Binding | denotes | the primary ligand-binding component type 1 IL-10R (IL-10R1) |
T6347 | 822-840 | Transcription | denotes | gene transcription |
T6346 | 141-191 | Binding | denotes | IL-10 binds to the IL-10 receptor (IL-10R) complex |
T6345 | 713-840 | Regulation | denotes | STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription |
T6344 | 713-840 | Regulation | denotes | STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription |
T6283 | 680-689 | Protein | denotes | STAT1 [3] |
T6191 | 1035-1040 | Protein | denotes | STAT3 |
T6190 | 856-861 | Protein | denotes | STAT3 |
T6188 | 757-808 | Entity | denotes | heterodimers, rapidly translocate into the nucleus, |
T6186 | 111-139 | Protein | denotes | of proinflammatory cytokines |
T6178 | 291-328 | Protein | denotes | the accessory component type 2 IL-10R |
T6176 | 1705-1713 | Protein | denotes | by IL-10 |
T6171 | 278-285 | Protein | denotes | IL-10R1 |
T6169 | 378-429 | Protein | denotes | the Janus kinase (JAK) family tyrosine kinases Jak1 |
T6168 | 743-753 | Entity | denotes | homodimers |
T6167 | 226-286 | Entity | denotes | the primary ligand-binding component type 1 IL-10R (IL-10R1) |
T6241 | 796-807 | Entity | denotes | the nucleus |
T6234 | 493-506 | Protein | denotes | type 2 IL-10R |
T6232 | 1263-1267 | Protein | denotes | SOCS |
T6231 | 1467-1494 | Protein | denotes | cytokine signaling pathways |
T6230 | 408-416 | Entity | denotes | tyrosine |
T6228 | 924-936 | Protein | denotes | IL-6-derived |
T6227 | 388-400 | Protein | denotes | kinase (JAK) |
T6225 | 9-23 | Protein | denotes | a key cytokine |
T6224 | 1314-1346 | Protein | denotes | endogenous JAK kinase inhibitors |
T6221 | 1651-1656 | Protein | denotes | STAT3 |
T6219 | 363-369 | Protein | denotes | IL-10R |
T6216 | 580-675 | Protein | denotes | of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 |
T6215 | 353-358 | Protein | denotes | IL-10 |
T6213 | 1549-1554 | Protein | denotes | SOCS3 |
T6211 | 1325-1328 | Protein | denotes | JAK |
T6208 | 481-488 | Protein | denotes | IL-10R1 |
T6199 | 822-826 | Protein | denotes | gene |
T6198 | 382-387 | Protein | denotes | Janus |
T6282 | 1069-1083 | Protein | denotes | IL-10-mediated |
T6279 | 1676-1683 | Protein | denotes | by IL-6 |
T6275 | 1225-1268 | Protein | denotes | The suppressor of cytokine signaling (SOCS) |
T6274 | 153-191 | Protein | denotes | to the IL-10 receptor (IL-10R) complex |
T6272 | 723-728 | Protein | denotes | STAT3 |
T6267 | 1171-1184 | Protein | denotes | IL-6-mediated |
T6263 | 540-564 | Entity | denotes | tyrosine phosphorylation |
T6259 | 396-399 | Protein | denotes | JAK |
T6256 | 526-531 | Protein | denotes | IL-10 |
T6298 | 1014-1018 | Protein | denotes | mice |
T6297 | 176-182 | Protein | denotes | IL-10R |
T6295 | 976-1003 | Protein | denotes | of cell-type-specific STAT3 |
T6294 | 1115-1126 | Entity | denotes | macrophages |
T6289 | 0-5 | Protein | denotes | IL-10 |
T6286 | 1610-1615 | Protein | denotes | IL-10 |
T6341 | 1626-1713 | Negative_regulation | denotes | by specifically blocking STAT3 activation induced by IL-6 but not that induced by IL-10 |
T6336 | 1212-1223 | Entity | denotes | T cells [6] |
T6330 | 434-438 | Protein | denotes | Tyk2 |
T6326 | 1269-1277 | Protein | denotes | proteins |
T6322 | 141-146 | Protein | denotes | IL-10 |
T6321 | 1314-1346 | Entity | denotes | endogenous JAK kinase inhibitors |
T6317 | 1069-1147 | Entity | denotes | IL-10-mediated anti-inflammatory reactions in macrophages and neutrophils [5], |
T6316 | 1131-1142 | Entity | denotes | neutrophils |
T6313 | 888-919 | Entity | denotes | IL-10-derived anti-inflammatory |
T6311 | 723-737 | Protein | denotes | STAT3 proteins |
T6310 | 1314-1346 | Protein | denotes | endogenous JAK kinase inhibitors |
T6307 | 888-901 | Protein | denotes | IL-10-derived |
T6306 | 153-191 | Entity | denotes | to the IL-10 receptor (IL-10R) complex |
T6304 | 253-286 | Protein | denotes | component type 1 IL-10R (IL-10R1) |
T6374 | 569-675 | Positive_regulation | denotes | activation of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 |
T6372 | 1155-1208 | Regulation | denotes | responsible for IL-6-mediated prevention of apoptosis |
T6369 | 1024-1051 | Positive_regulation | denotes | shown that STAT3 activation |
T6356 | 440-506 | Binding | denotes | which are constitutively associated with IL-10R1 and type 2 IL-10R |
R3098 | T6199 | T6347 | themeOf | gene,gene transcription |
R3101 | T6208 | T6356 | themeOf | IL-10R1,which are constitutively associated with IL-10R1 and type 2 IL-10R |
R3105 | T6215 | T6354 | themeOf | IL-10,The interaction of IL-10 and IL-10R |
R3107 | T6191 | T6369 | themeOf | STAT3,shown that STAT3 activation |
R3108 | T6216 | T6374 | themeOf | of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3,activation of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 |
R3110 | T6219 | T6354 | themeOf | IL-10R,The interaction of IL-10 and IL-10R |
R3111 | T6221 | T6353 | themeOf | STAT3,STAT3 activation induced by IL-6 but not that induced by IL-10 |
R3119 | T6267 | T6372 | causeOf | IL-6-mediated,responsible for IL-6-mediated prevention of apoptosis |
R3120 | T6234 | T6355 | themeOf | type 2 IL-10R,which are constitutively associated with IL-10R1 and type 2 IL-10R |
R3123 | T6250 | T6345 | causeOf | STAT1,"STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription" |
R3128 | T6304 | T6349 | themeOf | component type 1 IL-10R (IL-10R1),the primary ligand-binding component type 1 IL-10R (IL-10R1) |
R3130 | T6306 | T6346 | themeOf | to the IL-10 receptor (IL-10R) complex,IL-10 binds to the IL-10 receptor (IL-10R) complex |
R3132 | T6353 | T6341 | themeOf | STAT3 activation induced by IL-6 but not that induced by IL-10,by specifically blocking STAT3 activation induced by IL-6 but not that induced by IL-10 |
R3134 | T6311 | T6344 | causeOf | STAT3 proteins,"STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription" |
R3135 | T6322 | T6346 | themeOf | IL-10,IL-10 binds to the IL-10 receptor (IL-10R) complex |
R3144 | T6347 | T6344 | themeOf | gene transcription,"STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription" |
R3147 | T6347 | T6345 | themeOf | gene transcription,"STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription" |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5202 | 1719-1720 | . | denotes | . |
T5201 | 1718-1719 | NNP | denotes | ] |
T5200 | 1715-1718 | CD | denotes | 8,9 |
T5199 | 1714-1715 | NNP | denotes | [ |
T5198 | 1708-1713 | NNP | denotes | IL-10 |
T5197 | 1705-1707 | IN | denotes | by |
T5196 | 1697-1704 | VBN | denotes | induced |
T5195 | 1692-1696 | IN | denotes | that |
T5194 | 1688-1691 | RB | denotes | not |
T5193 | 1684-1687 | CC | denotes | but |
T5192 | 1679-1683 | NN | denotes | IL-6 |
T5191 | 1676-1678 | IN | denotes | by |
T5190 | 1668-1675 | VBN | denotes | induced |
T5189 | 1657-1667 | NN | denotes | activation |
T5188 | 1651-1656 | CD | denotes | STAT3 |
T5187 | 1642-1650 | VBG | denotes | blocking |
T5186 | 1629-1641 | RB | denotes | specifically |
T5185 | 1626-1628 | IN | denotes | by |
T5184 | 1624-1625 | , | denotes | , |
T5183 | 1620-1624 | NNP | denotes | IL-6 |
T5182 | 1616-1619 | CC | denotes | and |
T5181 | 1610-1615 | NNP | denotes | IL-10 |
T5180 | 1607-1609 | IN | denotes | of |
T5179 | 1600-1606 | NN | denotes | action |
T5178 | 1590-1599 | JJ | denotes | divergent |
T5177 | 1586-1589 | DT | denotes | the |
T5176 | 1575-1585 | VBG | denotes | regulating |
T5175 | 1572-1574 | IN | denotes | in |
T5174 | 1567-1571 | NN | denotes | role |
T5173 | 1563-1566 | JJ | denotes | key |
T5172 | 1561-1562 | DT | denotes | a |
T5171 | 1555-1560 | VBZ | denotes | plays |
T5170 | 1549-1554 | CD | denotes | SOCS3 |
T5169 | 1544-1548 | IN | denotes | that |
T5101 | 1148-1151 | CC | denotes | but |
T5100 | 1146-1147 | , | denotes | , |
T5099 | 1145-1146 | NNP | denotes | ] |
T5098 | 1144-1145 | CD | denotes | 5 |
T5097 | 1143-1144 | VBP | denotes | [ |
T5096 | 1131-1142 | NNS | denotes | neutrophils |
T5095 | 1127-1130 | CC | denotes | and |
T5094 | 1115-1126 | NNS | denotes | macrophages |
T5093 | 1112-1114 | IN | denotes | in |
T5092 | 1102-1111 | NNS | denotes | reactions |
T5091 | 1084-1101 | JJ | denotes | anti-inflammatory |
T5090 | 1069-1083 | JJ | denotes | IL-10-mediated |
T5089 | 1065-1068 | IN | denotes | for |
T5088 | 1055-1064 | JJ | denotes | essential |
T5087 | 1052-1054 | VBZ | denotes | is |
T5086 | 1041-1051 | NN | denotes | activation |
T5085 | 1035-1040 | CD | denotes | STAT3 |
T5084 | 1030-1034 | IN | denotes | that |
T5083 | 1024-1029 | VBN | denotes | shown |
T5082 | 1019-1023 | VBP | denotes | have |
T5081 | 1014-1018 | NNS | denotes | mice |
T5080 | 998-1013 | JJ | denotes | STAT3-deficient |
T5079 | 979-997 | JJ | denotes | cell-type-specific |
T5078 | 976-978 | IN | denotes | of |
T5077 | 968-975 | NNS | denotes | Studies |
T5076 | 966-967 | . | denotes | . |
T5075 | 965-966 | NNP | denotes | ] |
T5074 | 964-965 | CD | denotes | 4 |
T5073 | 963-964 | VBP | denotes | [ |
T5072 | 953-962 | NNS | denotes | responses |
T5071 | 937-952 | JJ | denotes | proinflammatory |
T5070 | 924-936 | JJ | denotes | IL-6-derived |
T5069 | 920-923 | CC | denotes | and |
T5068 | 902-919 | JJ | denotes | anti-inflammatory |
T5067 | 888-901 | JJ | denotes | IL-10-derived |
T5066 | 883-887 | DT | denotes | both |
T5065 | 879-882 | IN | denotes | for |
T5064 | 865-878 | JJ | denotes | indispensable |
T5063 | 862-864 | VBZ | denotes | is |
T5062 | 856-861 | NNP | denotes | STAT3 |
T5061 | 854-855 | , | denotes | , |
T5060 | 842-854 | RB | denotes | Intriguingly |
T5059 | 840-841 | . | denotes | . |
T5058 | 827-840 | NN | denotes | transcription |
T5057 | 822-826 | NN | denotes | gene |
T5056 | 813-821 | VB | denotes | modulate |
T5055 | 809-812 | CC | denotes | and |
T5054 | 807-808 | , | denotes | , |
T5053 | 800-807 | NN | denotes | nucleus |
T5052 | 796-799 | DT | denotes | the |
T5051 | 791-795 | IN | denotes | into |
T5050 | 779-790 | VBP | denotes | translocate |
T5049 | 771-778 | RB | denotes | rapidly |
T5048 | 769-770 | , | denotes | , |
T5047 | 757-769 | NNS | denotes | heterodimers |
T5046 | 754-756 | CC | denotes | or |
T5045 | 743-753 | NNS | denotes | homodimers |
T5044 | 738-742 | VBP | denotes | form |
T5043 | 729-737 | NNS | denotes | proteins |
T5042 | 723-728 | NNP | denotes | STAT3 |
T5041 | 719-722 | CC | denotes | and |
T5040 | 713-718 | NNP | denotes | STAT1 |
T5039 | 711-712 | , | denotes | , |
T5038 | 696-711 | NN | denotes | phosphorylation |
T5037 | 691-695 | IN | denotes | Upon |
T5036 | 689-690 | . | denotes | . |
T5035 | 688-689 | NNP | denotes | ] |
T5034 | 687-688 | CD | denotes | 3 |
T5033 | 686-687 | NN | denotes | [ |
T5032 | 680-685 | CD | denotes | STAT1 |
T5031 | 676-679 | CC | denotes | and |
T5030 | 674-675 | CD | denotes | 3 |
T5029 | 672-673 | -RRB- | denotes | ) |
T5028 | 668-672 | NNP | denotes | STAT |
T5027 | 667-668 | -LRB- | denotes | ( |
T5026 | 653-666 | NN | denotes | transcription |
T5025 | 650-652 | IN | denotes | of |
T5024 | 640-649 | NN | denotes | activator |
T5023 | 636-639 | CC | denotes | and |
T5022 | 625-635 | NN | denotes | transducer |
T5021 | 618-624 | VBP | denotes | signal |
T5020 | 610-617 | NNS | denotes | factors |
T5019 | 594-609 | JJ | denotes | transcriptional |
T5018 | 587-593 | NN | denotes | latent |
T5017 | 583-586 | DT | denotes | the |
T5016 | 580-582 | IN | denotes | of |
T5015 | 569-579 | NN | denotes | activation |
T5014 | 565-568 | CC | denotes | and |
T5013 | 549-564 | NN | denotes | phosphorylation |
T5012 | 540-548 | JJ | denotes | tyrosine |
T5011 | 532-539 | VBZ | denotes | induces |
T5010 | 526-531 | NN | denotes | IL-10 |
T5009 | 524-525 | . | denotes | . |
T5008 | 523-524 | NN | denotes | ] |
T5007 | 522-523 | CD | denotes | 2 |
T5006 | 521-522 | JJ | denotes | [ |
T5005 | 508-520 | RB | denotes | respectively |
T5004 | 506-507 | , | denotes | , |
T5003 | 500-506 | NN | denotes | IL-10R |
T5002 | 498-499 | CD | denotes | 2 |
T5001 | 493-497 | NN | denotes | type |
T5000 | 489-492 | CC | denotes | and |
T4999 | 481-488 | NNP | denotes | IL-10R1 |
T4998 | 476-480 | IN | denotes | with |
T4997 | 465-475 | VBN | denotes | associated |
T4996 | 450-464 | RB | denotes | constitutively |
T4995 | 446-449 | VBP | denotes | are |
T4994 | 440-445 | WDT | denotes | which |
T4993 | 438-439 | , | denotes | , |
T4992 | 434-438 | NNP | denotes | Tyk2 |
T4991 | 430-433 | CC | denotes | and |
T4990 | 425-429 | NNP | denotes | Jak1 |
T4989 | 417-424 | VBZ | denotes | kinases |
T4988 | 408-416 | NN | denotes | tyrosine |
T4987 | 401-407 | NN | denotes | family |
T4986 | 399-400 | -RRB- | denotes | ) |
T4985 | 396-399 | NNP | denotes | JAK |
T4984 | 395-396 | -LRB- | denotes | ( |
T4983 | 388-394 | NN | denotes | kinase |
T4982 | 382-387 | NNP | denotes | Janus |
T4981 | 378-381 | DT | denotes | the |
T4980 | 370-377 | VBZ | denotes | engages |
T4979 | 363-369 | NNP | denotes | IL-10R |
T4978 | 359-362 | CC | denotes | and |
T4977 | 353-358 | NNP | denotes | IL-10 |
T4976 | 350-352 | IN | denotes | of |
T4975 | 338-349 | NN | denotes | interaction |
T4974 | 334-337 | DT | denotes | The |
T4973 | 332-333 | . | denotes | . |
T4972 | 331-332 | NNP | denotes | ] |
T4971 | 330-331 | CD | denotes | 1 |
T4970 | 329-330 | NNP | denotes | [ |
T4969 | 322-328 | NNP | denotes | IL-10R |
T4968 | 320-321 | CD | denotes | 2 |
T4967 | 315-319 | NN | denotes | type |
T4966 | 305-314 | NN | denotes | component |
T4965 | 295-304 | JJ | denotes | accessory |
T4964 | 291-294 | DT | denotes | the |
T4963 | 287-290 | CC | denotes | and |
T4962 | 285-286 | -RRB- | denotes | ) |
T4961 | 278-285 | NN | denotes | IL-10R1 |
T4960 | 277-278 | -LRB- | denotes | ( |
T4959 | 270-276 | NN | denotes | IL-10R |
T4958 | 268-269 | CD | denotes | 1 |
T4957 | 263-267 | NN | denotes | type |
T4956 | 253-262 | NN | denotes | component |
T4955 | 238-252 | JJ | denotes | ligand-binding |
T4954 | 230-237 | JJ | denotes | primary |
T4953 | 226-229 | DT | denotes | the |
T4952 | 224-225 | , | denotes | , |
T4951 | 216-224 | NNS | denotes | subunits |
T4950 | 212-215 | CD | denotes | two |
T4949 | 209-211 | IN | denotes | of |
T4948 | 200-208 | VBN | denotes | composed |
T4947 | 197-199 | VBZ | denotes | is |
T4946 | 192-196 | WDT | denotes | that |
T4945 | 184-191 | NN | denotes | complex |
T4944 | 182-183 | -RRB- | denotes | ) |
T4943 | 176-182 | NN | denotes | IL-10R |
T4942 | 175-176 | -LRB- | denotes | ( |
T4941 | 166-174 | NN | denotes | receptor |
T4940 | 160-165 | NN | denotes | IL-10 |
T4939 | 156-159 | DT | denotes | the |
T4938 | 153-155 | TO | denotes | to |
T4937 | 147-152 | NNS | denotes | binds |
T4936 | 141-146 | JJ | denotes | IL-10 |
T4935 | 139-140 | . | denotes | . |
T4934 | 130-139 | NNS | denotes | cytokines |
T4933 | 114-129 | JJ | denotes | proinflammatory |
T4932 | 111-113 | IN | denotes | of |
T4931 | 102-110 | NN | denotes | function |
T4930 | 98-101 | CC | denotes | and |
T4929 | 87-97 | NN | denotes | production |
T4928 | 83-86 | DT | denotes | the |
T4927 | 72-82 | VBG | denotes | inhibiting |
T4926 | 69-71 | IN | denotes | by |
T4925 | 62-68 | RB | denotes | mainly |
T4924 | 60-61 | , | denotes | , |
T4923 | 51-60 | NNS | denotes | responses |
T4922 | 38-50 | JJ | denotes | inflammatory |
T4921 | 27-37 | VBG | denotes | regulating |
T4920 | 24-26 | IN | denotes | in |
T4919 | 15-23 | NN | denotes | cytokine |
T4918 | 11-14 | JJ | denotes | key |
T4917 | 9-10 | DT | denotes | a |
T4916 | 6-8 | VBZ | denotes | is |
T4915 | 0-5 | NN | denotes | IL-10 |
T5168 | 1535-1543 | VBP | denotes | indicate |
T5167 | 1527-1534 | NNS | denotes | studies |
T5166 | 1520-1526 | JJ | denotes | Recent |
T5165 | 1518-1519 | . | denotes | . |
T5164 | 1517-1518 | NNP | denotes | ] |
T5163 | 1516-1517 | CD | denotes | 7 |
T5162 | 1515-1516 | NNP | denotes | [ |
T5161 | 1505-1514 | VBN | denotes | clarified |
T5160 | 1500-1504 | VBN | denotes | been |
T5159 | 1495-1499 | VBP | denotes | have |
T5158 | 1486-1494 | NNS | denotes | pathways |
T5157 | 1476-1485 | VBG | denotes | signaling |
T5156 | 1467-1475 | NN | denotes | cytokine |
T5155 | 1458-1466 | VBG | denotes | opposing |
T5154 | 1455-1457 | IN | denotes | by |
T5153 | 1444-1454 | NN | denotes | inhibition |
T5152 | 1434-1443 | NN | denotes | crosstalk |
T5151 | 1431-1433 | IN | denotes | of |
T5150 | 1421-1430 | NNS | denotes | mediators |
T5149 | 1417-1420 | DT | denotes | the |
T5148 | 1414-1416 | IN | denotes | as |
T5147 | 1408-1413 | NNS | denotes | roles |
T5146 | 1402-1407 | PRP$ | denotes | their |
T5145 | 1398-1401 | CC | denotes | but |
T5144 | 1396-1397 | , | denotes | , |
T5143 | 1391-1396 | NNS | denotes | loops |
T5142 | 1380-1390 | NN | denotes | inhibition |
T5141 | 1371-1379 | NN | denotes | feedback |
T5140 | 1363-1370 | JJ | denotes | classic |
T5139 | 1360-1362 | IN | denotes | in |
T5138 | 1356-1359 | VB | denotes | act |
T5137 | 1352-1355 | MD | denotes | can |
T5136 | 1347-1351 | WDT | denotes | that |
T5135 | 1336-1346 | NNS | denotes | inhibitors |
T5134 | 1329-1335 | NN | denotes | kinase |
T5133 | 1325-1328 | NNP | denotes | JAK |
T5132 | 1314-1324 | JJ | denotes | endogenous |
T5131 | 1311-1313 | IN | denotes | of |
T5130 | 1304-1310 | NN | denotes | family |
T5129 | 1302-1303 | DT | denotes | a |
T5128 | 1299-1301 | IN | denotes | as |
T5127 | 1288-1298 | VBN | denotes | identified |
T5126 | 1283-1287 | VBN | denotes | been |
T5125 | 1278-1282 | VBP | denotes | have |
T5124 | 1269-1277 | NNS | denotes | proteins |
T5123 | 1267-1268 | -RRB- | denotes | ) |
T5122 | 1263-1267 | NNP | denotes | SOCS |
T5121 | 1262-1263 | -LRB- | denotes | ( |
T5120 | 1252-1261 | VBG | denotes | signaling |
T5119 | 1243-1251 | NN | denotes | cytokine |
T5118 | 1240-1242 | IN | denotes | of |
T5117 | 1229-1239 | NN | denotes | suppressor |
T5116 | 1225-1228 | DT | denotes | The |
T5115 | 1223-1224 | . | denotes | . |
T5114 | 1222-1223 | NNP | denotes | ] |
T5113 | 1221-1222 | CD | denotes | 6 |
T5112 | 1220-1221 | NNP | denotes | [ |
T5111 | 1214-1219 | NNS | denotes | cells |
T5110 | 1212-1213 | NNP | denotes | T |
T5109 | 1209-1211 | IN | denotes | in |
T5108 | 1199-1208 | NN | denotes | apoptosis |
T5107 | 1196-1198 | IN | denotes | of |
T5106 | 1185-1195 | NN | denotes | prevention |
T5105 | 1171-1184 | JJ | denotes | IL-6-mediated |
T5104 | 1167-1170 | IN | denotes | for |
T5103 | 1155-1166 | JJ | denotes | responsible |
T5102 | 1152-1154 | VBZ | denotes | is |
R1976 | T4915 | T4916 | nsubj | IL-10,is |
R1978 | T4916 | T4916 | ROOT | is,is |
R1979 | T4917 | T4919 | det | a,cytokine |
R1982 | T4918 | T4919 | amod | key,cytokine |
R1983 | T4919 | T4916 | attr | cytokine,is |
R1984 | T4920 | T4919 | prep | in,cytokine |
R1985 | T4921 | T4920 | pcomp | regulating,in |
R1986 | T4922 | T4923 | amod | inflammatory,responses |
R1987 | T4923 | T4921 | dobj | responses,regulating |
R1988 | T4924 | T4919 | punct | ",",cytokine |
R1989 | T4971 | T4972 | nummod | 1,] |
R1990 | T4972 | T4970 | appos | ],[ |
R1991 | T4973 | T4937 | punct | .,binds |
R1992 | T4925 | T4926 | advmod | mainly,by |
R1993 | T4974 | T4975 | det | The,interaction |
R1994 | T4975 | T4980 | nsubj | interaction,engages |
R1995 | T4976 | T4975 | prep | of,interaction |
R1996 | T4926 | T4916 | prep | by,is |
R1997 | T4977 | T4976 | pobj | IL-10,of |
R1998 | T4978 | T4977 | cc | and,IL-10 |
R1999 | T4927 | T4926 | pcomp | inhibiting,by |
R2000 | T4979 | T4977 | conj | IL-10R,IL-10 |
R2001 | T4980 | T4980 | ROOT | engages,engages |
R2002 | T4981 | T4983 | det | the,kinase |
R2003 | T4982 | T4983 | compound | Janus,kinase |
R2004 | T4928 | T4929 | det | the,production |
R2005 | T4983 | T4980 | dobj | kinase,engages |
R2006 | T4984 | T4983 | punct | (,kinase |
R2007 | T4985 | T4983 | appos | JAK,kinase |
R2008 | T4929 | T4927 | dobj | production,inhibiting |
R2009 | T4986 | T4985 | punct | ),JAK |
R2010 | T4987 | T4988 | compound | family,tyrosine |
R2011 | T4988 | T4989 | nsubj | tyrosine,kinases |
R2012 | T4930 | T4929 | cc | and,production |
R2013 | T4989 | T4983 | parataxis | kinases,kinase |
R2014 | T4990 | T4989 | dobj | Jak1,kinases |
R2015 | T4991 | T4990 | cc | and,Jak1 |
R2016 | T4931 | T4929 | conj | function,production |
R2017 | T4932 | T4929 | prep | of,production |
R2018 | T4992 | T4990 | conj | Tyk2,Jak1 |
R2019 | T4993 | T4983 | punct | ",",kinase |
R2020 | T4933 | T4934 | amod | proinflammatory,cytokines |
R2021 | T4994 | T4997 | nsubjpass | which,associated |
R2022 | T4995 | T4997 | auxpass | are,associated |
R2023 | T4996 | T4997 | advmod | constitutively,associated |
R2024 | T4934 | T4932 | pobj | cytokines,of |
R2025 | T4997 | T4983 | relcl | associated,kinase |
R2026 | T4998 | T4997 | prep | with,associated |
R2027 | T4999 | T4998 | pobj | IL-10R1,with |
R2028 | T5000 | T4997 | cc | and,associated |
R2029 | T5001 | T5003 | nmod | type,IL-10R |
R2030 | T4935 | T4916 | punct | .,is |
R2031 | T5002 | T5003 | nummod | 2,IL-10R |
R2032 | T5003 | T4997 | conj | IL-10R,associated |
R2033 | T5004 | T5003 | punct | ",",IL-10R |
R2034 | T4936 | T4937 | amod | IL-10,binds |
R2035 | T5005 | T5006 | advmod | respectively,[ |
R2036 | T5006 | T5008 | quantmod | [,] |
R2037 | T5007 | T5008 | nummod | 2,] |
R2038 | T5008 | T5003 | appos | ],IL-10R |
R2039 | T4937 | T4937 | ROOT | binds,binds |
R2040 | T5009 | T4980 | punct | .,engages |
R2041 | T5010 | T5011 | nsubj | IL-10,induces |
R2042 | T5011 | T5011 | ROOT | induces,induces |
R2043 | T4938 | T4937 | prep | to,binds |
R2044 | T5012 | T5013 | compound | tyrosine,phosphorylation |
R2045 | T5013 | T5011 | dobj | phosphorylation,induces |
R2046 | T4939 | T4941 | det | the,receptor |
R2047 | T5014 | T5013 | cc | and,phosphorylation |
R2048 | T5015 | T5013 | conj | activation,phosphorylation |
R2049 | T5016 | T5013 | prep | of,phosphorylation |
R2050 | T5017 | T5020 | det | the,factors |
R2051 | T4940 | T4941 | compound | IL-10,receptor |
R2052 | T5018 | T5020 | amod | latent,factors |
R2053 | T5019 | T5020 | amod | transcriptional,factors |
R2054 | T5020 | T5016 | pobj | factors,of |
R2055 | T4941 | T4938 | pobj | receptor,to |
R2056 | T5021 | T5011 | conj | signal,induces |
R2057 | T5022 | T5021 | dobj | transducer,signal |
R2058 | T5023 | T5022 | cc | and,transducer |
R2059 | T4942 | T4941 | punct | (,receptor |
R2060 | T5024 | T5022 | conj | activator,transducer |
R2061 | T5025 | T5024 | prep | of,activator |
R2062 | T5026 | T5025 | pobj | transcription,of |
R2063 | T4943 | T4941 | appos | IL-10R,receptor |
R2064 | T5027 | T5026 | punct | (,transcription |
R2065 | T5028 | T5026 | appos | STAT,transcription |
R2066 | T5029 | T5026 | punct | ),transcription |
R2067 | T4944 | T4941 | punct | ),receptor |
R2068 | T4945 | T4937 | appos | complex,binds |
R2069 | T5030 | T5026 | nummod | 3,transcription |
R2070 | T4946 | T4948 | nsubjpass | that,composed |
R2071 | T5031 | T5024 | cc | and,activator |
R2072 | T5032 | T5033 | nummod | STAT1,[ |
R2073 | T5033 | T5024 | conj | [,activator |
R2074 | T4947 | T4948 | auxpass | is,composed |
R2075 | T5034 | T5035 | nummod | 3,] |
R2076 | T5035 | T5033 | appos | ],[ |
R2077 | T5036 | T5011 | punct | .,induces |
R2078 | T5037 | T5044 | prep | Upon,form |
R2079 | T5038 | T5037 | pobj | phosphorylation,Upon |
R2080 | T5039 | T5044 | punct | ",",form |
R2081 | T4948 | T4937 | relcl | composed,binds |
R2082 | T5040 | T5043 | nmod | STAT1,proteins |
R2083 | T5041 | T5040 | cc | and,STAT1 |
R2084 | T5042 | T5040 | conj | STAT3,STAT1 |
R2085 | T4949 | T4948 | prep | of,composed |
R2086 | T5043 | T5044 | nsubj | proteins,form |
R2087 | T5044 | T5044 | ROOT | form,form |
R2088 | T5045 | T5044 | dobj | homodimers,form |
R2089 | T4950 | T4951 | nummod | two,subunits |
R2090 | T5046 | T5045 | cc | or,homodimers |
R2091 | T5047 | T5045 | conj | heterodimers,homodimers |
R2092 | T5048 | T5044 | punct | ",",form |
R2093 | T4951 | T4949 | pobj | subunits,of |
R2094 | T5049 | T5050 | advmod | rapidly,translocate |
R2095 | T5050 | T5044 | conj | translocate,form |
R2096 | T5051 | T5050 | prep | into,translocate |
R2097 | T4952 | T4951 | punct | ",",subunits |
R2098 | T5052 | T5053 | det | the,nucleus |
R2099 | T5053 | T5051 | pobj | nucleus,into |
R2100 | T5054 | T5050 | punct | ",",translocate |
R2101 | T4953 | T4956 | det | the,component |
R2102 | T5055 | T5050 | cc | and,translocate |
R2103 | T5056 | T5050 | conj | modulate,translocate |
R2104 | T5057 | T5058 | compound | gene,transcription |
R2105 | T4954 | T4956 | amod | primary,component |
R2106 | T5058 | T5056 | dobj | transcription,modulate |
R2107 | T5059 | T5044 | punct | .,form |
R2108 | T5060 | T5063 | advmod | Intriguingly,is |
R2109 | T4955 | T4956 | amod | ligand-binding,component |
R2110 | T5061 | T5063 | punct | ",",is |
R2111 | T5062 | T5063 | nsubj | STAT3,is |
R2112 | T5063 | T5063 | ROOT | is,is |
R2113 | T4956 | T4957 | compound | component,type |
R2114 | T5064 | T5063 | acomp | indispensable,is |
R2115 | T5065 | T5063 | prep | for,is |
R2116 | T5066 | T5072 | det | both,responses |
R2117 | T4957 | T4951 | appos | type,subunits |
R2118 | T5067 | T5072 | amod | IL-10-derived,responses |
R2119 | T4958 | T4959 | nummod | 1,IL-10R |
R2120 | T4959 | T4957 | appos | IL-10R,type |
R2121 | T5068 | T5072 | nmod | anti-inflammatory,responses |
R2122 | T4960 | T4961 | punct | (,IL-10R1 |
R2123 | T5069 | T5068 | cc | and,anti-inflammatory |
R2124 | T5070 | T5068 | conj | IL-6-derived,anti-inflammatory |
R2125 | T4961 | T4959 | appos | IL-10R1,IL-10R |
R2126 | T5071 | T5072 | amod | proinflammatory,responses |
R2127 | T5072 | T5065 | pobj | responses,for |
R2128 | T4962 | T4961 | punct | ),IL-10R1 |
R2129 | T5073 | T5075 | nmod | [,] |
R2130 | T5074 | T5075 | nummod | 4,] |
R2131 | T5075 | T5063 | npadvmod | ],is |
R2132 | T4963 | T4959 | cc | and,IL-10R |
R2133 | T5076 | T5063 | punct | .,is |
R2134 | T5077 | T5083 | nsubj | Studies,shown |
R2135 | T4964 | T4966 | det | the,component |
R2136 | T5078 | T5077 | prep | of,Studies |
R2137 | T5079 | T5081 | amod | cell-type-specific,mice |
R2138 | T4965 | T4966 | compound | accessory,component |
R2139 | T5080 | T5081 | amod | STAT3-deficient,mice |
R2140 | T5081 | T5078 | pobj | mice,of |
R2141 | T5082 | T5083 | aux | have,shown |
R2142 | T4966 | T4967 | compound | component,type |
R2143 | T5083 | T5083 | ROOT | shown,shown |
R2144 | T5084 | T5087 | mark | that,is |
R2145 | T4967 | T4959 | conj | type,IL-10R |
R2146 | T5085 | T5086 | nummod | STAT3,activation |
R2147 | T5086 | T5087 | nsubj | activation,is |
R2148 | T5087 | T5083 | ccomp | is,shown |
R2149 | T4968 | T4967 | nummod | 2,type |
R2150 | T5088 | T5087 | acomp | essential,is |
R2151 | T5089 | T5088 | prep | for,essential |
R2152 | T5090 | T5092 | amod | IL-10-mediated,reactions |
R2153 | T4969 | T4970 | compound | IL-10R,[ |
R2154 | T5091 | T5092 | amod | anti-inflammatory,reactions |
R2155 | T5092 | T5089 | pobj | reactions,for |
R2156 | T5093 | T5092 | prep | in,reactions |
R2157 | T4970 | T4967 | appos | [,type |
R2158 | T5094 | T5093 | pobj | macrophages,in |
R2159 | T5095 | T5094 | cc | and,macrophages |
R2160 | T5096 | T5094 | conj | neutrophils,macrophages |
R2161 | T5165 | T5127 | punct | .,identified |
R2162 | T5097 | T5099 | nmod | [,] |
R2163 | T5098 | T5099 | nummod | 5,] |
R2164 | T5099 | T5083 | dobj | ],shown |
R2165 | T5100 | T5083 | punct | ",",shown |
R2166 | T5166 | T5167 | amod | Recent,studies |
R2167 | T5101 | T5083 | cc | but,shown |
R2168 | T5102 | T5083 | conj | is,shown |
R2169 | T5103 | T5102 | acomp | responsible,is |
R2170 | T5104 | T5103 | prep | for,responsible |
R2171 | T5167 | T5168 | nsubj | studies,indicate |
R2172 | T5105 | T5106 | amod | IL-6-mediated,prevention |
R2173 | T5106 | T5104 | pobj | prevention,for |
R2174 | T5107 | T5106 | prep | of,prevention |
R2175 | T5168 | T5168 | ROOT | indicate,indicate |
R2176 | T5108 | T5107 | pobj | apoptosis,of |
R2177 | T5109 | T5106 | prep | in,prevention |
R2178 | T5110 | T5111 | compound | T,cells |
R2179 | T5111 | T5109 | pobj | cells,in |
R2180 | T5112 | T5114 | nmod | [,] |
R2181 | T5113 | T5114 | nummod | 6,] |
R2182 | T5169 | T5171 | mark | that,plays |
R2183 | T5114 | T5114 | ROOT | ],] |
R2184 | T5115 | T5083 | punct | .,shown |
R2185 | T5116 | T5117 | det | The,suppressor |
R2186 | T5170 | T5171 | nsubj | SOCS3,plays |
R2187 | T5117 | T5117 | ROOT | suppressor,suppressor |
R2188 | T5118 | T5117 | prep | of,suppressor |
R2189 | T5119 | T5118 | pobj | cytokine,of |
R2190 | T5171 | T5168 | ccomp | plays,indicate |
R2191 | T5120 | T5117 | acl | signaling,suppressor |
R2192 | T5121 | T5120 | punct | (,signaling |
R2193 | T5122 | T5120 | appos | SOCS,signaling |
R2194 | T5172 | T5174 | det | a,role |
R2195 | T5123 | T5120 | punct | ),signaling |
R2196 | T5124 | T5127 | nsubjpass | proteins,identified |
R2197 | T5125 | T5127 | aux | have,identified |
R2198 | T5173 | T5174 | amod | key,role |
R2199 | T5126 | T5127 | auxpass | been,identified |
R2200 | T5127 | T5127 | ROOT | identified,identified |
R2201 | T5128 | T5127 | prep | as,identified |
R2202 | T5174 | T5171 | dobj | role,plays |
R2203 | T5129 | T5130 | det | a,family |
R2204 | T5130 | T5128 | pobj | family,as |
R2205 | T5175 | T5174 | prep | in,role |
R2206 | T5131 | T5130 | prep | of,family |
R2207 | T5132 | T5135 | amod | endogenous,inhibitors |
R2208 | T5133 | T5135 | nmod | JAK,inhibitors |
R2209 | T5134 | T5135 | compound | kinase,inhibitors |
R2210 | T5176 | T5175 | pcomp | regulating,in |
R2211 | T5135 | T5131 | pobj | inhibitors,of |
R2212 | T5136 | T5138 | nsubj | that,act |
R2213 | T5137 | T5138 | aux | can,act |
R2214 | T5177 | T5179 | det | the,action |
R2215 | T5138 | T5135 | relcl | act,inhibitors |
R2216 | T5139 | T5138 | prep | in,act |
R2217 | T5140 | T5143 | amod | classic,loops |
R2218 | T5178 | T5179 | amod | divergent,action |
R2219 | T5141 | T5142 | compound | feedback,inhibition |
R2220 | T5142 | T5143 | compound | inhibition,loops |
R2221 | T5143 | T5139 | pobj | loops,in |
R2222 | T5179 | T5176 | dobj | action,regulating |
R2223 | T5144 | T5127 | punct | ",",identified |
R2224 | T5145 | T5127 | cc | but,identified |
R2225 | T5146 | T5147 | poss | their,roles |
R2226 | T5180 | T5179 | prep | of,action |
R2227 | T5147 | T5127 | conj | roles,identified |
R2228 | T5148 | T5147 | prep | as,roles |
R2229 | T5149 | T5150 | det | the,mediators |
R2230 | T5150 | T5148 | pobj | mediators,as |
R2231 | T5181 | T5180 | pobj | IL-10,of |
R2232 | T5151 | T5150 | prep | of,mediators |
R2233 | T5152 | T5153 | compound | crosstalk,inhibition |
R2234 | T5153 | T5151 | pobj | inhibition,of |
R2235 | T5182 | T5181 | cc | and,IL-10 |
R2236 | T5154 | T5127 | agent | by,identified |
R2237 | T5155 | T5154 | pcomp | opposing,by |
R2238 | T5156 | T5155 | dobj | cytokine,opposing |
R2239 | T5183 | T5181 | conj | IL-6,IL-10 |
R2240 | T5157 | T5155 | conj | signaling,opposing |
R2241 | T5158 | T5161 | nsubjpass | pathways,clarified |
R2242 | T5184 | T5171 | punct | ",",plays |
R2243 | T5159 | T5161 | aux | have,clarified |
R2244 | T5160 | T5161 | auxpass | been,clarified |
R2245 | T5161 | T5157 | ccomp | clarified,signaling |
R2246 | T5185 | T5171 | prep | by,plays |
R2247 | T5162 | T5164 | nmod | [,] |
R2248 | T5163 | T5164 | nummod | 7,] |
R2249 | T5164 | T5161 | dobj | ],clarified |
R2250 | T5186 | T5187 | advmod | specifically,blocking |
R2251 | T5187 | T5185 | pcomp | blocking,by |
R2252 | T5188 | T5189 | nummod | STAT3,activation |
R2253 | T5189 | T5187 | dobj | activation,blocking |
R2256 | T5190 | T5189 | acl | induced,activation |
R2260 | T5191 | T5190 | agent | by,induced |
R2264 | T5192 | T5191 | pobj | IL-6,by |
R2268 | T5193 | T5190 | cc | but,induced |
R2272 | T5194 | T5196 | neg | not,induced |
R2275 | T5195 | T5196 | nsubj | that,induced |
R2283 | T5196 | T5190 | conj | induced,induced |
R2287 | T5197 | T5196 | agent | by,induced |
R2291 | T5198 | T5199 | compound | IL-10,[ |
R2295 | T5199 | T5197 | pobj | [,by |
R2298 | T5200 | T5201 | nummod | "8,9",] |
R2303 | T5201 | T5199 | appos | ],[ |
R2307 | T5202 | T5168 | punct | .,indicate |
bionlp-st-ge-2016-test-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3752 | 1575-1585 | Regulation | denotes | regulating |
T3751 | 1575-1585 | Regulation | denotes | regulating |
T3750 | 1679-1683 | Protein | denotes | IL-6 |
T3749 | 1651-1656 | Protein | denotes | STAT3 |
T3748 | 1620-1624 | Protein | denotes | IL-6 |
T3747 | 1610-1615 | Protein | denotes | IL-10 |
T3746 | 1549-1554 | Protein | denotes | SOCS3 |
T3745 | 1336-1346 | Negative_regulation | denotes | inhibitors |
T3744 | 1325-1335 | Protein | denotes | JAK kinase |
T3743 | 1243-1277 | Protein | denotes | cytokine signaling (SOCS) proteins |
T3742 | 1041-1051 | Positive_regulation | denotes | activation |
T3741 | 1004-1013 | Negative_regulation | denotes | deficient |
T3740 | 1069-1074 | Protein | denotes | IL-10 |
T3739 | 1035-1040 | Protein | denotes | STAT3 |
T3738 | 998-1003 | Protein | denotes | STAT3 |
T3737 | 856-861 | Protein | denotes | STAT3 |
T3736 | 779-790 | Localization | denotes | translocate |
T3735 | 779-790 | Localization | denotes | translocate |
T3734 | 800-807 | Entity | denotes | nucleus |
T3733 | 696-711 | Phosphorylation | denotes | phosphorylation |
T3732 | 696-711 | Phosphorylation | denotes | phosphorylation |
T3731 | 723-737 | Protein | denotes | STAT3 proteins |
T3730 | 713-718 | Protein | denotes | STAT1 |
T3729 | 532-539 | Positive_regulation | denotes | induces |
T3728 | 569-579 | Positive_regulation | denotes | activation |
T3727 | 540-548 | Entity | denotes | tyrosine |
T3726 | 587-617 | Protein | denotes | latent transcriptional factors |
T3725 | 526-531 | Protein | denotes | IL-10 |
T3724 | 493-506 | Protein | denotes | type 2 IL-10R |
T3723 | 481-488 | Protein | denotes | IL-10R1 |
T3722 | 434-438 | Protein | denotes | Tyk2 |
T3721 | 425-429 | Protein | denotes | Jak1 |
T3720 | 401-424 | Protein | denotes | family tyrosine kinases |
T3719 | 396-399 | Protein | denotes | JAK |
T3718 | 382-394 | Protein | denotes | Janus kinase |
T3717 | 363-369 | Protein | denotes | IL-10R |
T3716 | 353-358 | Protein | denotes | IL-10 |
T3715 | 238-252 | Binding | denotes | ligand-binding |
T3714 | 238-252 | Binding | denotes | ligand-binding |
T3713 | 147-152 | Binding | denotes | binds |
T3712 | 147-152 | Binding | denotes | binds |
T3711 | 147-152 | Binding | denotes | binds |
T3710 | 278-285 | Protein | denotes | IL-10R1 |
T3709 | 263-276 | Protein | denotes | type 1 IL-10R |
T3708 | 176-182 | Protein | denotes | IL-10R |
T3707 | 160-174 | Protein | denotes | IL-10 receptor |
T3706 | 141-146 | Protein | denotes | IL-10 |
T3705 | 0-5 | Protein | denotes | IL-10 |
R958 | T3706 | T3711 | themeOf | IL-10,binds |
R959 | T3706 | T3712 | themeOf | IL-10,binds |
R960 | T3706 | T3713 | themeOf | IL-10,binds |
R961 | T3707 | T3712 | themeOf | IL-10 receptor,binds |
R962 | T3708 | T3713 | themeOf | IL-10R,binds |
R963 | T3709 | T3714 | themeOf | type 1 IL-10R,ligand-binding |
R964 | T3710 | T3715 | themeOf | IL-10R1,ligand-binding |
R965 | T3725 | T3729 | causeOf | IL-10,induces |
R966 | T3726 | T3728 | themeOf | latent transcriptional factors,activation |
R967 | T3726 | T3727 | partOf | latent transcriptional factors,tyrosine |
R968 | T3728 | T3729 | themeOf | activation,induces |
R969 | T3730 | T3732 | themeOf | STAT1,phosphorylation |
R970 | T3730 | T3735 | themeOf | STAT1,translocate |
R971 | T3731 | T3733 | themeOf | STAT3 proteins,phosphorylation |
R972 | T3731 | T3736 | themeOf | STAT3 proteins,translocate |
R973 | T3734 | T3735 | locationOf | nucleus,translocate |
R974 | T3734 | T3736 | locationOf | nucleus,translocate |
R975 | T3738 | T3741 | themeOf | STAT3,deficient |
R976 | T3739 | T3742 | themeOf | STAT3,activation |
R977 | T3744 | T3745 | themeOf | JAK kinase,inhibitors |
R978 | T3747 | T3751 | themeOf | IL-10,regulating |
R979 | T3748 | T3752 | themeOf | IL-6,regulating |
test3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2369 | 1708-1713 | Protein | denotes | IL-10 |
T2368 | 1697-1704 | Positive_regulation | denotes | induced |
T2367 | 1679-1683 | Protein | denotes | IL-6 |
T2366 | 1668-1675 | Positive_regulation | denotes | induced |
T2365 | 1657-1667 | Positive_regulation | denotes | activation |
T2364 | 1651-1656 | Protein | denotes | STAT3 |
T2363 | 1642-1650 | Negative_regulation | denotes | blocking |
T2362 | 1620-1624 | Protein | denotes | IL-6 |
T2361 | 1610-1615 | Protein | denotes | IL-10 |
T2360 | 1575-1585 | Regulation | denotes | regulating |
T2359 | 1567-1571 | Regulation | denotes | role |
T2358 | 1549-1554 | Protein | denotes | SOCS3 |
T2357 | 1171-1175 | Protein | denotes | IL-6 |
T2356 | 1069-1074 | Protein | denotes | IL-10 |
T2355 | 1041-1051 | Positive_regulation | denotes | activation |
T2354 | 1035-1040 | Protein | denotes | STAT3 |
T2353 | 1004-1013 | Negative_regulation | denotes | deficient |
T2352 | 998-1003 | Protein | denotes | STAT3 |
T2351 | 924-928 | Protein | denotes | IL-6 |
T2350 | 888-893 | Protein | denotes | IL-10 |
T2349 | 856-861 | Protein | denotes | STAT3 |
T2348 | 779-790 | Localization | denotes | translocate |
T2347 | 723-728 | Protein | denotes | STAT3 |
T2346 | 713-718 | Protein | denotes | STAT1 |
T2345 | 696-711 | Phosphorylation | denotes | phosphorylation |
T2344 | 680-685 | Protein | denotes | STAT1 |
T2343 | 618-675 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
T2342 | 569-579 | Positive_regulation | denotes | activation |
T2341 | 549-564 | Phosphorylation | denotes | phosphorylation |
T2340 | 532-539 | Positive_regulation | denotes | induces |
T2339 | 526-531 | Protein | denotes | IL-10 |
T2338 | 493-506 | Protein | denotes | type 2 IL-10R |
T2337 | 481-488 | Protein | denotes | IL-10R1 |
T2336 | 465-475 | Binding | denotes | associated |
T2335 | 434-438 | Protein | denotes | Tyk2 |
T2334 | 425-429 | Protein | denotes | Jak1 |
T2333 | 370-377 | Binding | denotes | engages |
T2332 | 363-369 | Protein | denotes | IL-10R |
T2331 | 353-358 | Protein | denotes | IL-10 |
T2330 | 338-349 | Binding | denotes | interaction |
T2329 | 315-328 | Protein | denotes | type 2 IL-10R |
T2328 | 278-285 | Protein | denotes | IL-10R1 |
T2327 | 263-276 | Protein | denotes | type 1 IL-10R |
T2326 | 245-252 | Binding | denotes | binding |
T2325 | 176-182 | Protein | denotes | IL-10R |
T2324 | 160-174 | Protein | denotes | IL-10 receptor |
T2323 | 147-152 | Binding | denotes | binds |
T2322 | 141-146 | Protein | denotes | IL-10 |
T2287 | 1708-1713 | Protein | denotes | IL-10 |
T2286 | 1679-1683 | Protein | denotes | IL-6 |
T2285 | 1651-1656 | Protein | denotes | STAT3 |
T2284 | 1620-1624 | Protein | denotes | IL-6 |
T2283 | 1610-1615 | Protein | denotes | IL-10 |
T2282 | 1549-1554 | Protein | denotes | SOCS3 |
T2281 | 1171-1175 | Protein | denotes | IL-6 |
T2280 | 1069-1074 | Protein | denotes | IL-10 |
T2279 | 1035-1040 | Protein | denotes | STAT3 |
T2278 | 998-1003 | Protein | denotes | STAT3 |
T2277 | 924-928 | Protein | denotes | IL-6 |
T2276 | 888-893 | Protein | denotes | IL-10 |
T2275 | 856-861 | Protein | denotes | STAT3 |
T2274 | 723-728 | Protein | denotes | STAT3 |
T2273 | 713-718 | Protein | denotes | STAT1 |
T2272 | 680-685 | Protein | denotes | STAT1 |
T2271 | 618-675 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
T2270 | 526-531 | Protein | denotes | IL-10 |
T2269 | 493-506 | Protein | denotes | type 2 IL-10R |
T2268 | 481-488 | Protein | denotes | IL-10R1 |
T2267 | 434-438 | Protein | denotes | Tyk2 |
T2266 | 425-429 | Protein | denotes | Jak1 |
T2265 | 363-369 | Protein | denotes | IL-10R |
T2264 | 353-358 | Protein | denotes | IL-10 |
T2263 | 315-328 | Protein | denotes | type 2 IL-10R |
T2262 | 278-285 | Protein | denotes | IL-10R1 |
T2261 | 263-276 | Protein | denotes | type 1 IL-10R |
T2260 | 176-182 | Protein | denotes | IL-10R |
T2259 | 160-174 | Protein | denotes | IL-10 receptor |
T2258 | 141-146 | Protein | denotes | IL-10 |
T2257 | 1-5 | Protein | denotes | L-10 |
T2256 | 2-5 | Protein | denotes | -10 |
R783 | T2335 | T2333 | themeOf | Tyk2,engages |
R784 | T2337 | T2336 | themeOf | IL-10R1,associated |
R785 | T2338 | T2336 | themeOf | type 2 IL-10R,associated |
R786 | T2339 | T2340 | causeOf | IL-10,induces |
R787 | T2341 | T2340 | themeOf | phosphorylation,induces |
R788 | T2343 | T2342 | themeOf | signal transducer and activator of transcription (STAT) 3,activation |
R789 | T2344 | T2342 | themeOf | STAT1,activation |
R790 | T2346 | T2348 | themeOf | STAT1,translocate |
R791 | T2346 | T2345 | themeOf | STAT1,phosphorylation |
R792 | T2347 | T2345 | themeOf | STAT3,phosphorylation |
R793 | T2347 | T2348 | themeOf | STAT3,translocate |
R794 | T2352 | T2353 | themeOf | STAT3,deficient |
R795 | T2354 | T2355 | themeOf | STAT3,activation |
R796 | T2358 | T2363 | causeOf | SOCS3,blocking |
R797 | T2358 | T2359 | causeOf | SOCS3,role |
R798 | T2364 | T2365 | themeOf | STAT3,activation |
R799 | T2365 | T2366 | themeOf | activation,induced |
R800 | T2365 | T2363 | themeOf | activation,blocking |
R801 | T2367 | T2366 | causeOf | IL-6,induced |
R802 | T2369 | T2368 | causeOf | IL-10,induced |
R768 | T2322 | T2323 | themeOf | IL-10,binds |
R769 | T2324 | T2323 | themeOf | IL-10 receptor,binds |
R770 | T2325 | T2324 | equivalentTo | IL-10R,IL-10 receptor |
R771 | T2327 | T2326 | themeOf | type 1 IL-10R,binding |
R772 | T2328 | T2327 | equivalentTo | IL-10R1,type 1 IL-10R |
R773 | T2329 | T2326 | themeOf | type 2 IL-10R,binding |
R774 | T2331 | T2333 | themeOf | IL-10,engages |
R775 | T2331 | T2330 | themeOf | IL-10,interaction |
R776 | T2331 | T2336 | themeOf | IL-10,associated |
R777 | T2332 | T2330 | themeOf | IL-10R,interaction |
R778 | T2334 | T2330 | themeOf | Jak1,interaction |
R779 | T2334 | T2336 | themeOf | Jak1,associated |
R780 | T2334 | T2333 | themeOf | Jak1,engages |
R781 | T2335 | T2336 | themeOf | Tyk2,associated |
R782 | T2335 | T2330 | themeOf | Tyk2,interaction |
testone
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2110 | 1708-1713 | Protein | denotes | IL-10 |
T2109 | 1679-1683 | Protein | denotes | IL-6 |
T2108 | 1651-1656 | Protein | denotes | STAT3 |
T2107 | 1620-1624 | Protein | denotes | IL-6 |
T2106 | 1610-1615 | Protein | denotes | IL-10 |
T2105 | 1549-1554 | Protein | denotes | SOCS3 |
T2104 | 1171-1175 | Protein | denotes | IL-6 |
T2103 | 1069-1074 | Protein | denotes | IL-10 |
T2102 | 1035-1040 | Protein | denotes | STAT3 |
T2101 | 998-1003 | Protein | denotes | STAT3 |
T2100 | 924-928 | Protein | denotes | IL-6 |
T2099 | 888-893 | Protein | denotes | IL-10 |
T2098 | 856-861 | Protein | denotes | STAT3 |
T2097 | 723-728 | Protein | denotes | STAT3 |
T2096 | 713-718 | Protein | denotes | STAT1 |
T2095 | 680-685 | Protein | denotes | STAT1 |
T2094 | 618-675 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
T2084 | 526-531 | Protein | denotes | IL-10 |
T2083 | 493-506 | Protein | denotes | type 2 IL-10R |
T2082 | 481-488 | Protein | denotes | IL-10R1 |
T2081 | 434-438 | Protein | denotes | Tyk2 |
T2080 | 425-429 | Protein | denotes | Jak1 |
T2079 | 363-369 | Protein | denotes | IL-10R |
T2078 | 353-358 | Protein | denotes | IL-10 |
T2077 | 315-328 | Protein | denotes | type 2 IL-10R |
T2076 | 278-285 | Protein | denotes | IL-10R1 |
T2075 | 263-276 | Protein | denotes | type 1 IL-10R |
T2074 | 176-182 | Protein | denotes | IL-10R |
T2073 | 160-174 | Protein | denotes | IL-10 receptor |
T2072 | 141-146 | Protein | denotes | IL-10 |
T2071 | 1-5 | Protein | denotes | L-10 |
T2161 | 1697-1704 | Positive_regulation | denotes | induced |
T2160 | 1668-1675 | Positive_regulation | denotes | induced |
T2159 | 1657-1667 | Positive_regulation | denotes | activation |
T2158 | 1642-1650 | Negative_regulation | denotes | blocking |
T2157 | 1575-1585 | Regulation | denotes | regulating |
T2156 | 1041-1051 | Positive_regulation | denotes | activation |
T2155 | 1004-1013 | Negative_regulation | denotes | deficient |
T2154 | 800-807 | Entity | denotes | nucleus |
T2153 | 779-790 | Localization | denotes | translocate |
T2152 | 696-711 | Phosphorylation | denotes | phosphorylation |
T2151 | 549-564 | Phosphorylation | denotes | phosphorylation |
T2150 | 532-539 | Positive_regulation | denotes | induces |
T2149 | 465-475 | Binding | denotes | associated |
T2148 | 370-377 | Binding | denotes | engages |
T2147 | 338-349 | Binding | denotes | interaction |
T2146 | 147-152 | Binding | denotes | binds |
R711 | T2072 | T2146 | themeOf | IL-10,binds |
R712 | T2073 | T2146 | themeOf | IL-10 receptor,binds |
R713 | T2074 | T2073 | equivalentTo | IL-10R,IL-10 receptor |
R714 | T2076 | T2075 | equivalentTo | IL-10R1,type 1 IL-10R |
R715 | T2078 | T2148 | themeOf | IL-10,engages |
R716 | T2078 | T2147 | themeOf | IL-10,interaction |
R717 | T2078 | T2149 | themeOf | IL-10,associated |
R718 | T2079 | T2148 | themeOf | IL-10R,engages |
R719 | T2079 | T2147 | themeOf | IL-10R,interaction |
R720 | T2081 | T2149 | themeOf | Tyk2,associated |
R721 | T2081 | T2148 | themeOf | Tyk2,engages |
R722 | T2082 | T2149 | themeOf | IL-10R1,associated |
R723 | T2083 | T2149 | themeOf | type 2 IL-10R,associated |
R724 | T2084 | T2150 | causeOf | IL-10,induces |
R729 | T2096 | T2153 | themeOf | STAT1,translocate |
R730 | T2096 | T2152 | themeOf | STAT1,phosphorylation |
R731 | T2097 | T2152 | themeOf | STAT3,phosphorylation |
R732 | T2097 | T2153 | themeOf | STAT3,translocate |
R733 | T2101 | T2155 | themeOf | STAT3,deficient |
R734 | T2102 | T2156 | themeOf | STAT3,activation |
R735 | T2106 | T2157 | themeOf | IL-10,regulating |
R736 | T2107 | T2158 | causeOf | IL-6,blocking |
R737 | T2108 | T2159 | themeOf | STAT3,activation |
R738 | T2109 | T2160 | causeOf | IL-6,induced |
R739 | T2109 | T2158 | causeOf | IL-6,blocking |
R740 | T2110 | T2160 | causeOf | IL-10,induced |
R741 | T2110 | T2161 | causeOf | IL-10,induced |
R759 | T2151 | T2150 | themeOf | phosphorylation,induces |
R760 | T2154 | T2153 | locationOf | nucleus,translocate |
R761 | T2159 | T2160 | themeOf | activation,induced |
R762 | T2159 | T2158 | themeOf | activation,blocking |
R763 | T2160 | T2158 | themeOf | induced,blocking |