PMC:1064873 / 1680-7010
Annnotations
LappsTest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2245 | 5300-5304 | Protein | denotes | CD4+ |
| T2244 | 5264-5274 | Protein | denotes | SOCS3 mRNA |
| T2243 | 5254-5259 | Protein | denotes | SOCS1 |
| T2242 | 5225-5230 | Protein | denotes | IL-10 |
| T2241 | 5200-5205 | Protein | denotes | STAT3 |
| T2240 | 5190-5195 | Protein | denotes | STAT1 |
| T2239 | 5166-5171 | Protein | denotes | IL-10 |
| T2238 | 5028-5032 | Protein | denotes | CD4+ |
| T2237 | 4886-4890 | Protein | denotes | CD28 |
| T2236 | 4768-4772 | Protein | denotes | CD86 |
| T2235 | 4759-4763 | Protein | denotes | CD80 |
| T2234 | 4644-4681 | Protein | denotes | cytotoxic T-cell-associated antigen 4 |
| T2233 | 4416-4433 | Protein | denotes | rheumatoid factor |
| T2232 | 4343-4347 | Protein | denotes | CD4+ |
| T2231 | 4304-4307 | Protein | denotes | IFN |
| T2230 | 4286-4302 | Protein | denotes | interferon gamma |
| T2229 | 4216-4220 | Protein | denotes | CD11 |
| T2228 | 4207-4211 | Protein | denotes | CD69 |
| T2227 | 4026-4030 | Protein | denotes | CD4+ |
| T2226 | 3954-3958 | Protein | denotes | CD86 |
| T2225 | 3945-3949 | Protein | denotes | CD80 |
| T2224 | 3931-3935 | Protein | denotes | CD28 |
| T2223 | 3899-3921 | Protein | denotes | MHC class II molecules |
| T2222 | 3759-3794 | Protein | denotes | MHC class II antigens HLA-DRB1*0404 |
| T2221 | 3551-3555 | Protein | denotes | CD4+ |
| T2220 | 3496-3544 | Protein | denotes | granulocyte–macrophage colony-stimulating factor |
| T2219 | 3486-3490 | Protein | denotes | IL-1 |
| T2218 | 3479-3483 | Protein | denotes | TNF- |
| T2217 | 3401-3408 | Protein | denotes | IL-10R1 |
| T2216 | 3339-3343 | Protein | denotes | IL-1 |
| T2215 | 3329-3333 | Protein | denotes | TNF- |
| T2214 | 3227-3232 | Protein | denotes | IL-10 |
| T2213 | 3132-3137 | Protein | denotes | IL-10 |
| T2212 | 2455-2459 | Protein | denotes | IL-6 |
| T2211 | 2389-2405 | Protein | denotes | matrix proteases |
| T2210 | 2373-2387 | Protein | denotes | growth factors |
| T2209 | 2167-2171 | Protein | denotes | IL-1 |
| T2208 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T2207 | 1692-1696 | Protein | denotes | IL-6 |
| T2206 | 1664-1669 | Protein | denotes | STAT3 |
| T2205 | 1633-1637 | Protein | denotes | IL-6 |
| T2204 | 1623-1628 | Protein | denotes | IL-10 |
| T2203 | 1562-1567 | Protein | denotes | SOCS3 |
| T2202 | 1338-1348 | Protein | denotes | JAK kinase |
| T2201 | 1276-1280 | Protein | denotes | SOCS |
| T2200 | 1184-1188 | Protein | denotes | IL-6 |
| T2199 | 1082-1087 | Protein | denotes | IL-10 |
| T2198 | 1048-1053 | Protein | denotes | STAT3 |
| T2197 | 1011-1016 | Protein | denotes | STAT3 |
| T2196 | 937-941 | Protein | denotes | IL-6 |
| T2195 | 901-932 | Protein | denotes | IL-10-derived anti-inflammatory |
| T2194 | 869-874 | Protein | denotes | STAT3 |
| T2193 | 736-750 | Protein | denotes | STAT3 proteins |
| T2192 | 726-731 | Protein | denotes | STAT1 |
| T2191 | 693-698 | Protein | denotes | STAT1 |
| T2190 | 681-685 | Protein | denotes | STAT |
| T2189 | 600-648 | Protein | denotes | latent transcriptional factors signal transducer |
| T2188 | 539-544 | Protein | denotes | IL-10 |
| T2187 | 494-501 | Protein | denotes | IL-10R1 |
| T2186 | 447-451 | Protein | denotes | Tyk2 |
| T2185 | 438-442 | Protein | denotes | Jak1 |
| T2184 | 409-412 | Protein | denotes | JAK |
| T2183 | 395-407 | Protein | denotes | Janus kinase |
| T2182 | 376-382 | Protein | denotes | IL-10R |
| T2181 | 366-371 | Protein | denotes | IL-10 |
| T2180 | 291-298 | Protein | denotes | IL-10R1 |
| T2179 | 276-289 | Protein | denotes | type 1 IL-10R |
| T2178 | 189-195 | Protein | denotes | IL-10R |
| T2177 | 173-187 | Protein | denotes | IL-10 receptor |
| T2176 | 154-159 | Protein | denotes | IL-10 |
| T2175 | 13-18 | Protein | denotes | IL-10 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 15535835-11244051-4156862 | 343-344 | 11244051 | denotes | 1 |
| 15535835-10347215-4156863 | 535-536 | 10347215 | denotes | 2 |
| 15535835-7543512-4156864 | 700-701 | 7543512 | denotes | 3 |
| 15535835-12039028-4156865 | 977-978 | 12039028 | denotes | 4 |
| 15535835-10023769-4156866 | 1157-1158 | 10023769 | denotes | 5 |
| 15535835-9794394-4156867 | 1234-1235 | 9794394 | denotes | 6 |
| 15535835-11527983-4156868 | 1529-1530 | 11527983 | denotes | 7 |
| 15535835-12754507-4156869 | 1728-1729 | 12754507 | denotes | 8 |
| 15535835-12626585-4156870 | 1730-1731 | 12626585 | denotes | 9 |
| 15535835-8717520-4156871 | 2450-2452 | 8717520 | denotes | 10 |
| 15535835-12746890-4156872 | 2717-2719 | 12746890 | denotes | 11 |
| 15535835-8163935-4156873 | 3082-3084 | 8163935 | denotes | 12 |
| 15535835-11046056-4156874 | 3366-3368 | 11046056 | denotes | 13 |
| 15535835-12782719-4156875 | 3369-3371 | 12782719 | denotes | 14 |
| 15535835-10553089-4156876 | 3546-3548 | 10553089 | denotes | 15 |
| 15535835-2446635-4156877 | 3855-3857 | 2446635 | denotes | 16 |
| 15535835-7738179-4156878 | 3858-3860 | 7738179 | denotes | 17 |
| 15535835-8624620-4156879 | 3980-3982 | 8624620 | denotes | 18 |
| 15535835-8546719-4156879 | 3980-3982 | 8546719 | denotes | 18 |
| 15535835-10529123-4156879 | 3980-3982 | 10529123 | denotes | 18 |
| 15535835-12776222-4156880 | 4322-4324 | 12776222 | denotes | 21 |
| 15535835-11259725-4156881 | 4325-4327 | 11259725 | denotes | 22 |
| 15535835-14614165-4156882 | 4792-4794 | 14614165 | denotes | 23 |
| 15535835-10898505-4156883 | 4910-4912 | 10898505 | denotes | 24 |
biosemtest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3113 | 553-577 | UMLS/C1519726 | denotes | tyrosine phosphorylation |
| T3112 | 4291-4307 | UP/O35735 | denotes | feron gamma (IFN |
| T3111 | 4650-4659 | UMLS/C0677881 | denotes | xic T-cel |
| T3110 | 4897-4914 | UMLS/C0037080 | denotes | ing pathway [24], |
| T3109 | 1489-1507 | UMLS/C0037080 | denotes | signaling pathways |
| T3108 | 4177-4186 | UMLS/C0037083 | denotes | ling by m |
| T3107 | 3661-3670 | UMLS/C0037083 | denotes | ling, in |
| T3106 | 3234-3243 | UMLS/C0037083 | denotes | ignaling |
| T3105 | 3179-3198 | UMLS/C0037083 | denotes | ignal transduction |
| T3104 | 4291-4307 | UP/P63310 | denotes | feron gamma (IFN |
| T3103 | 2397-2406 | UP/P10270 | denotes | roteases, |
| T3102 | 3153-3162 | UMLS/C0443264 | denotes | odulated |
| T3101 | 826-834 | UMLS/C0443264 | denotes | modulate |
| T3100 | 1242-1274 | UP/Q62225 | denotes | suppressor of cytokine signaling |
| T3099 | 4422-4439 | UP/P04206 | denotes | toid factor and o |
| T3098 | 2827-2833 | UMLS/C1706309 | denotes | oints. |
| T3097 | 3950-3954 | UMLS/C1366561 | denotes | and |
| T3096 | 2260-2265 | UMLS/C1706309 | denotes | oint |
| T3095 | 2374-2388 | UP/Q776B5 | denotes | rowth factors, |
| T3094 | 1338-1348 | UMLS/C0597721 | denotes | JAK kinase |
| T3093 | 395-407 | UMLS/C0597721 | denotes | Janus kinase |
| T3092 | 4499-4503 | UMLS/C1704326 | denotes | n RA |
| T3091 | 1603-1612 | UMLS/C0443204 | denotes | divergent |
| T3090 | 4291-4307 | UP/Q1WM28 | denotes | feron gamma (IFN |
| T3089 | 2374-2388 | UP/P08441 | denotes | rowth factors, |
| T3088 | 5135-5139 | UMLS/C0075747 | denotes | stim |
| T3087 | 4892-4896 | UMLS/C0075747 | denotes | igna |
| T3086 | 4735-4739 | UMLS/C0075747 | denotes | n T |
| T3085 | 3936-3940 | UMLS/C0075747 | denotes | liga |
| T3084 | 3633-3637 | UMLS/C0075747 | denotes | medi |
| T3083 | 2827-2833 | UMLS/C0022417 | denotes | oints. |
| T3082 | 2260-2265 | UMLS/C0022417 | denotes | oint |
| T3081 | 2310-2320 | UMLS/C1705248 | denotes | omponents, |
| T3080 | 318-327 | UMLS/C1705248 | denotes | component |
| T3079 | 266-275 | UMLS/C1705248 | denotes | component |
| T3078 | 2397-2406 | UP/P07570 | denotes | roteases, |
| T3077 | 2224-2231 | UMLS/C1709694 | denotes | rocess |
| T3076 | 681-685 | UMLS/C1548425 | denotes | STAT |
| T3075 | 173-187 | UMLS/C0247771 | denotes | IL-10 receptor |
| T3074 | 4291-4307 | UP/O73915 | denotes | feron gamma (IFN |
| T3073 | 4291-4307 | UP/Q9YGB9 | denotes | feron gamma (IFN |
| T3072 | 4774-4778 | UMLS/C0527903 | denotes | ith |
| T3071 | 3959-3963 | UMLS/C0527903 | denotes | in |
| T3070 | 4291-4307 | UP/P79154 | denotes | feron gamma (IFN |
| T3069 | 4291-4307 | UP/P01579 | denotes | feron gamma (IFN |
| T3068 | 4554-4563 | UMLS/C0087111 | denotes | ent of ac |
| T3067 | 1966-1971 | UMLS/C1136359 | denotes | cells |
| T3066 | 4072-4075 | UMLS/C0454788 | denotes | e c |
| T3065 | 3569-3572 | UMLS/C0454788 | denotes | e a |
| T3064 | 4291-4307 | UP/P42160 | denotes | feron gamma (IFN |
| T3063 | 3732-3741 | UMLS/C1317973 | denotes | rted by t |
| T3062 | 4221-4225 | UMLS/C0054942 | denotes | as |
| T3061 | 1966-1971 | UMLS/C1948049 | denotes | cells |
| T3060 | 2773-2783 | UMLS/C1999216 | denotes | nhibitors |
| T3059 | 1759-1779 | UMLS/C0003873 | denotes | rheumatoid arthritis |
| T3058 | 4469-4480 | UMLS/C1948029 | denotes | ction. Thei |
| T3057 | 2266-2277 | UMLS/C1948029 | denotes | estruction, |
| T3056 | 4464-4468 | UMLS/C1266909 | denotes | estr |
| T3055 | 4242-4249 | UMLS/C1963578 | denotes | se of p |
| T3054 | 4291-4307 | UP/Q8MKF5 | denotes | feron gamma (IFN |
| T3053 | 4190-4195 | UMLS/C0876919 | denotes | of c |
| T3052 | 1168-1179 | UMLS/C1273518 | denotes | responsible |
| T3051 | 4368-4377 | UMLS/C1948023 | denotes | ate B-cel |
| T3050 | 1863-1874 | UMLS/C2697913 | denotes | lymphocytes |
| T3049 | 2374-2388 | UP/P01136 | denotes | rowth factors, |
| T3048 | 4291-4307 | UP/P28333 | denotes | feron gamma (IFN |
| T3047 | 1540-1547 | UMLS/C2603343 | denotes | studies |
| T3046 | 981-988 | UMLS/C2603343 | denotes | Studies |
| T3045 | 1144-1155 | UMLS/C0027950 | denotes | neutrophils |
| T3044 | 1863-1874 | UMLS/C0200635 | denotes | lymphocytes |
| T3043 | 3414-3423 | UMLS/C0547047 | denotes | creased i |
| T3042 | 2397-2406 | UP/P63122 | denotes | roteases, |
| T3041 | 1540-1547 | UMLS/C2349977 | denotes | studies |
| T3040 | 981-988 | UMLS/C2349977 | denotes | Studies |
| T3039 | 3276-3283 | UMLS/C1547296 | denotes | hronic |
| T3038 | 2397-2406 | UP/P63124 | denotes | roteases, |
| T3037 | 4422-4439 | UMLS/C0201660 | denotes | toid factor and o |
| T3036 | 751-755 | UMLS/C0348078 | denotes | form |
| T3035 | 4464-4468 | UMLS/C1266908 | denotes | estr |
| T3034 | 4321-4326 | UMLS/C0384648 | denotes | [21,2 |
| T3033 | 409-412 | UMLS/C1150611 | denotes | JAK |
| T3032 | 2288-2292 | UMLS/C1947971 | denotes | ive |
| T3031 | 1966-1971 | UMLS/C1704653 | denotes | cells |
| T3030 | 3823-3845 | UMLS/C0012655 | denotes | se susceptibility and |
| T3029 | 4821-4827 | UMLS/C0332206 | denotes | the a |
| T3028 | 4711-4716 | UMLS/C0332206 | denotes | the e |
| T3027 | 1655-1663 | UMLS/C0332206 | denotes | blocking |
| T3026 | 4574-4581 | UMLS/C0012634 | denotes | e by se |
| T3025 | 5055-5061 | UMLS/C1552596 | denotes | inhib |
| T3024 | 4469-4480 | UMLS/C1261381 | denotes | ction. Thei |
| T3023 | 2266-2277 | UMLS/C1261381 | denotes | estruction, |
| T3022 | 2827-2833 | UMLS/C0392905 | denotes | oints. |
| T3021 | 2260-2265 | UMLS/C0392905 | denotes | oint |
| T3020 | 835-853 | UMLS/C0040649 | denotes | gene transcription |
| T3019 | 607-622 | UMLS/C0040649 | denotes | transcriptional |
| T3018 | 2390-2396 | UMLS/C1704639 | denotes | atrix |
| T3017 | 2390-2396 | UMLS/C1704640 | denotes | atrix |
| T3016 | 2827-2833 | UMLS/C1269611 | denotes | oints. |
| T3015 | 2260-2265 | UMLS/C1269611 | denotes | oint |
| T3014 | 5197-5202 | UP/P42229 | denotes | nd ST |
| T3013 | 726-731 | UP/P42229 | denotes | STAT1 |
| T3012 | 693-698 | UP/P42229 | denotes | STAT1 |
| T3011 | 4567-4573 | UMLS/C1561511 | denotes | disea |
| T3010 | 4567-4573 | UMLS/C1561512 | denotes | disea |
| T3009 | 4567-4573 | UMLS/C1561513 | denotes | disea |
| T3008 | 1548-1556 | UMLS/C1444656 | denotes | indicate |
| T3007 | 421-437 | UMLS/C0033681 | denotes | tyrosine kinases |
| T3006 | 4865-4873 | UMLS/C1704632 | denotes | se by in |
| T3005 | 966-975 | UMLS/C1704632 | denotes | responses |
| T3004 | 3123-3129 | UMLS/C0441472 | denotes | ction |
| T3003 | 2560-2567 | UMLS/C0441472 | denotes | ctions |
| T3002 | 1613-1619 | UMLS/C0441472 | denotes | action |
| T3001 | 3075-3081 | UMLS/C0441471 | denotes | vents |
| T3000 | 197-204 | UMLS/C0439855 | denotes | complex |
| T2999 | 4897-4914 | UMLS/C0086982 | denotes | ing pathway [24], |
| T2998 | 1489-1507 | UMLS/C0086982 | denotes | signaling pathways |
| T2997 | 2332-2337 | UMLS/C1955473 | denotes | ther |
| T2996 | 4524-4532 | UMLS/C0332185 | denotes | ly prove |
| T2995 | 1533-1539 | UMLS/C0332185 | denotes | Recent |
| T2994 | 2397-2406 | UMLS/C1947941 | denotes | roteases, |
| T2993 | 2936-2944 | UMLS/C1513916 | denotes | egative |
| T2992 | 2810-2820 | UMLS/C1561573 | denotes | uantities |
| T2991 | 2936-2944 | UMLS/C0205160 | denotes | egative |
| T2990 | 1376-1383 | UMLS/C0439858 | denotes | classic |
| T2989 | 2178-2183 | UMLS/C0205164 | denotes | ajor |
| T2988 | 5055-5061 | UMLS/C0439851 | denotes | inhib |
| T2987 | 5055-5061 | UMLS/C1947931 | denotes | inhib |
| T2986 | 4924-4928 | UMLS/C0205170 | denotes | s in |
| T2985 | 4230-4234 | UMLS/C0205170 | denotes | as t |
| T2984 | 4321-4326 | UMLS/C1623218 | denotes | [21,2 |
| T2983 | 2397-2406 | UP/P63121 | denotes | roteases, |
| T2982 | 3284-3295 | UMLS/C0332157 | denotes | xposure to |
| T2981 | 4567-4573 | UMLS/C0205177 | denotes | disea |
| T2980 | 1966-1971 | UMLS/C1269647 | denotes | cells |
| T2979 | 4291-4307 | UP/Q865X1 | denotes | feron gamma (IFN |
| T2978 | 4774-4778 | UMLS/C1413243 | denotes | ith |
| T2977 | 3959-3963 | UMLS/C1413243 | denotes | in |
| T2976 | 4567-4573 | UMLS/C2347179 | denotes | disea |
| T2975 | 5020-5030 | UMLS/C0683598 | denotes | ance of CD |
| T2974 | 5232-5237 | UMLS/C0085295 | denotes | and t |
| T2973 | 5173-5178 | UMLS/C0085295 | denotes | the i |
| T2972 | 4803-4808 | UMLS/C0085295 | denotes | effic |
| T2971 | 3228-3233 | UMLS/C0085295 | denotes | L-10 |
| T2970 | 3133-3138 | UMLS/C0085295 | denotes | L-10 |
| T2969 | 2835-2840 | UMLS/C0085295 | denotes | L-10, |
| T2968 | 1721-1726 | UMLS/C0085295 | denotes | IL-10 |
| T2967 | 1623-1628 | UMLS/C0085295 | denotes | IL-10 |
| T2966 | 1082-1087 | UMLS/C0085295 | denotes | IL-10 |
| T2965 | 901-906 | UMLS/C0085295 | denotes | IL-10 |
| T2964 | 539-544 | UMLS/C0085295 | denotes | IL-10 |
| T2963 | 366-371 | UMLS/C0085295 | denotes | IL-10 |
| T2962 | 13-18 | UMLS/C0085295 | denotes | IL-10 |
| T2961 | 4464-4468 | UMLS/C0262950 | denotes | estr |
| T2960 | 3414-3423 | UMLS/C0392756 | denotes | creased i |
| T2959 | 4212-4216 | UMLS/C1413235 | denotes | and |
| T2958 | 2374-2388 | UMLS/C0018284 | denotes | rowth factors, |
| T2957 | 2224-2231 | UMLS/C1522240 | denotes | rocess |
| T2956 | 1242-1274 | UMLS/C0299250 | denotes | suppressor of cytokine signaling |
| T2955 | 4455-4463 | UMLS/C0086597 | denotes | ed bone |
| T2954 | 3638-3646 | UMLS/C0086597 | denotes | ted cost |
| T2953 | 1189-1197 | UMLS/C0086597 | denotes | mediated |
| T2952 | 1088-1096 | UMLS/C0086597 | denotes | mediated |
| T2951 | 2310-2320 | UMLS/C1179435 | denotes | omponents, |
| T2950 | 318-327 | UMLS/C1179435 | denotes | component |
| T2949 | 266-275 | UMLS/C1179435 | denotes | component |
| T2948 | 1242-1274 | UP/Q9PW70 | denotes | suppressor of cytokine signaling |
| T2947 | 2374-2388 | UP/P33804 | denotes | rowth factors, |
| T2946 | 4567-4573 | UMLS/C1561510 | denotes | disea |
| T2945 | 4567-4573 | UMLS/C1561509 | denotes | disea |
| T2944 | 3276-3283 | UMLS/C1555457 | denotes | hronic |
| T2943 | 4567-4573 | UMLS/C1561508 | denotes | disea |
| T2942 | 3972-3980 | UMLS/C0333348 | denotes | med ST [ |
| T2941 | 2338-2350 | UMLS/C0333348 | denotes | nflammatory |
| T2940 | 4567-4573 | UMLS/C1561507 | denotes | disea |
| T2939 | 4543-4553 | UMLS/C1272703 | denotes | sful treat |
| T2938 | 5213-5228 | UMLS/C0031715 | denotes | rylation by IL- |
| T2937 | 709-724 | UMLS/C0031715 | denotes | phosphorylation |
| T2936 | 2310-2320 | UMLS/C0729650 | denotes | omponents, |
| T2935 | 318-327 | UMLS/C0729650 | denotes | component |
| T2934 | 266-275 | UMLS/C0729650 | denotes | component |
| T2933 | 1317-1323 | UMLS/C1563343 | denotes | family |
| T2932 | 414-420 | UMLS/C1563343 | denotes | family |
| T2931 | 351-362 | UMLS/C1704675 | denotes | interaction |
| T2930 | 1568-1573 | UMLS/C0331781 | denotes | plays |
| T2929 | 4567-4573 | UMLS/C1547419 | denotes | disea |
| T2928 | 4865-4873 | UMLS/C0871261 | denotes | se by in |
| T2927 | 966-975 | UMLS/C0871261 | denotes | responses |
| T2926 | 1301-1311 | UMLS/C1551388 | denotes | identified |
| T2925 | 2804-2809 | UMLS/C0549177 | denotes | arge |
| T2924 | 2224-2231 | UMLS/C1551390 | denotes | rocess |
| T2923 | 3247-3255 | UMLS/C0221099 | denotes | mpaired |
| T2922 | 3997-4007 | UMLS/C0549178 | denotes | nuing emer |
| T2921 | 1317-1323 | UMLS/C1704727 | denotes | family |
| T2920 | 414-420 | UMLS/C1704727 | denotes | family |
| T2919 | 4321-4326 | UMLS/C1825592 | denotes | [21,2 |
| T2918 | 5135-5139 | UMLS/C1332709 | denotes | stim |
| T2917 | 4892-4896 | UMLS/C1332709 | denotes | igna |
| T2916 | 4735-4739 | UMLS/C1332709 | denotes | n T |
| T2915 | 3936-3940 | UMLS/C1332709 | denotes | liga |
| T2914 | 3633-3637 | UMLS/C1332709 | denotes | medi |
| T2913 | 3105-3122 | UMLS/C0003209 | denotes | nti-inflammatory |
| T2912 | 2732-2749 | UMLS/C0003209 | denotes | nti-inflammatory |
| T2911 | 1097-1114 | UMLS/C0003209 | denotes | anti-inflammatory |
| T2910 | 915-932 | UMLS/C0003209 | denotes | anti-inflammatory |
| T2909 | 2945-2954 | UMLS/C1704734 | denotes | egulator |
| T2908 | 4190-4195 | UMLS/C2348143 | denotes | of c |
| T2907 | 2945-2954 | UMLS/C1704735 | denotes | egulator |
| T2906 | 4291-4307 | UP/P01581 | denotes | feron gamma (IFN |
| T2905 | 4784-4788 | UMLS/C1299351 | denotes | vidi |
| T2904 | 4678-4687 | UP/Q26721 | denotes | n 4 (CD15 |
| T2903 | 2925-2930 | UMLS/C0205309 | denotes | nown |
| T2902 | 5020-5030 | UMLS/C0237834 | denotes | ance of CD |
| T2901 | 3850-3858 | UMLS/C0439793 | denotes | ity [16, |
| T2900 | 4554-4563 | UMLS/C1522326 | denotes | ent of ac |
| T2899 | 2397-2406 | UP/Q9BXR3 | denotes | roteases, |
| T2898 | 4072-4075 | UMLS/C0337876 | denotes | e c |
| T2837 | 907-914 | UMLS/C2348040 | denotes | derived |
| T2836 | 5062-5072 | UMLS/C1628982 | denotes | tion in RA |
| T2835 | 4595-4605 | UMLS/C1628982 | denotes | tion of T- |
| T2834 | 1457-1467 | UMLS/C1628982 | denotes | inhibition |
| T2833 | 2591-2611 | UMLS/C0001349 | denotes | cute-phase response, |
| T2832 | 1961-1965 | UMLS/C0870814 | denotes | like |
| T2831 | 3247-3255 | UMLS/C0684336 | denotes | mpaired |
| T2830 | 4291-4307 | UP/Q9TV67 | denotes | feron gamma (IFN |
| T2829 | 2426-2449 | UMLS/C0162772 | denotes | eactive oxygen species |
| T2828 | 4291-4307 | UP/O77763 | denotes | feron gamma (IFN |
| T2827 | 3414-3423 | UMLS/C0205216 | denotes | creased i |
| T2826 | 4291-4307 | UP/O57571 | denotes | feron gamma (IFN |
| T2825 | 1540-1547 | UMLS/C1705923 | denotes | studies |
| T2824 | 981-988 | UMLS/C1705923 | denotes | Studies |
| T2823 | 3153-3162 | UMLS/C1709059 | denotes | odulated |
| T2822 | 826-834 | UMLS/C1709059 | denotes | modulate |
| T2821 | 5207-5212 | UMLS/C1367307 | denotes | hosph |
| T2820 | 1664-1669 | UMLS/C1367307 | denotes | STAT3 |
| T2819 | 1048-1053 | UMLS/C1367307 | denotes | STAT3 |
| T2818 | 869-874 | UMLS/C1367307 | denotes | STAT3 |
| T2817 | 3276-3283 | UMLS/C0205191 | denotes | hronic |
| T2816 | 243-250 | UMLS/C0439631 | denotes | primary |
| T2815 | 4464-4468 | UMLS/C1550616 | denotes | estr |
| T2814 | 4144-4155 | UMLS/C1546634 | denotes | blasts thro |
| T2813 | 2523-2534 | UMLS/C1546634 | denotes | ibroblasts, |
| T2812 | 2061-2072 | UMLS/C1546634 | denotes | fibroblasts |
| T2811 | 1950-1960 | UMLS/C1546634 | denotes | fibroblast |
| T2810 | 4554-4563 | UMLS/C1533734 | denotes | ent of ac |
| T2809 | 2397-2406 | UP/P04024 | denotes | roteases, |
| T2808 | 2397-2406 | UP/P63129 | denotes | roteases, |
| T2807 | 4865-4873 | UMLS/C1706817 | denotes | se by in |
| T2806 | 966-975 | UMLS/C1706817 | denotes | responses |
| T2805 | 2174-2177 | UMLS/C0205448 | denotes | wo |
| T2804 | 225-228 | UMLS/C0205448 | denotes | two |
| T2803 | 1376-1383 | UMLS/C0439658 | denotes | classic |
| T2802 | 1576-1579 | UMLS/C1554080 | denotes | key |
| T2801 | 24-27 | UMLS/C1554080 | denotes | key |
| T2800 | 4678-4687 | UP/P0C873 | denotes | n 4 (CD15 |
| T2799 | 3206-3226 | UMLS/C0021376 | denotes | hronic inflammation. |
| T2798 | 2235-2255 | UMLS/C0021376 | denotes | hronic inflammation |
| T2797 | 4707-4710 | UMLS/C0006823 | denotes | ock |
| T2796 | 4362-4367 | UMLS/C0006823 | denotes | stimu |
| T2795 | 1365-1368 | UMLS/C0006823 | denotes | can |
| T2794 | 4678-4687 | UP/P31522 | denotes | n 4 (CD15 |
| T2793 | 2636-2648 | UMLS/C0032112 | denotes | lasma cells, |
| T2792 | 2408-2420 | UMLS/C0028128 | denotes | itric oxide, |
| T2791 | 4678-4687 | UP/B1JS09 | denotes | n 4 (CD15 |
| T2790 | 4119-4130 | UMLS/C1550652 | denotes | phages and |
| T2789 | 3259-3270 | UMLS/C1550652 | denotes | acrophages |
| T2788 | 2959-2969 | UMLS/C1550652 | denotes | acrophage |
| T2787 | 2854-2865 | UMLS/C1550652 | denotes | acrophages |
| T2786 | 2036-2047 | UMLS/C1550652 | denotes | macrophages |
| T2785 | 1876-1887 | UMLS/C1550652 | denotes | macrophages |
| T2784 | 1128-1139 | UMLS/C1550652 | denotes | macrophages |
| T2783 | 1242-1274 | UP/O70512 | denotes | suppressor of cytokine signaling |
| T2782 | 1863-1874 | UMLS/C1550651 | denotes | lymphocytes |
| T2781 | 3804-3817 | UMLS/C0968669 | denotes | RB1*0401 with |
| T2780 | 2568-2575 | UMLS/C1552866 | denotes | nclude |
| T2779 | 2322-2331 | UMLS/C1552866 | denotes | ncluding |
| T2778 | 2374-2388 | UP/Q86607 | denotes | rowth factors, |
| T2777 | 4064-4070 | UMLS/C1554106 | denotes | r, may |
| T2776 | 1808-1818 | UMLS/C1549537 | denotes | infiltrate |
| T2775 | 751-755 | UMLS/C1522492 | denotes | form |
| T2774 | 751-755 | UMLS/C0205431 | denotes | form |
| T2773 | 5207-5212 | UMLS/C0253050 | denotes | hosph |
| T2772 | 1664-1669 | UMLS/C0253050 | denotes | STAT3 |
| T2771 | 1048-1053 | UMLS/C0253050 | denotes | STAT3 |
| T2770 | 869-874 | UMLS/C0253050 | denotes | STAT3 |
| T2769 | 736-750 | UMLS/C0253050 | denotes | STAT3 proteins |
| T2768 | 2810-2820 | UMLS/C1554108 | denotes | uantities |
| T2767 | 1824-1831 | UMLS/C2346866 | denotes | variety |
| T2766 | 4144-4155 | UMLS/C1550637 | denotes | blasts thro |
| T2765 | 2523-2534 | UMLS/C1550637 | denotes | ibroblasts, |
| T2764 | 2061-2072 | UMLS/C1550637 | denotes | fibroblasts |
| T2763 | 1950-1960 | UMLS/C1550637 | denotes | fibroblast |
| T2762 | 2374-2388 | UP/Q8V307 | denotes | rowth factors, |
| T2761 | 1808-1818 | UMLS/C0332448 | denotes | infiltrate |
| T2760 | 4784-4788 | UMLS/C1522410 | denotes | vidi |
| T2759 | 1301-1311 | UMLS/C0205396 | denotes | identified |
| T2758 | 4291-4307 | UP/P49708 | denotes | feron gamma (IFN |
| T2757 | 1835-1853 | UMLS/C0440752 | denotes | inflammatory cells |
| T2756 | 4291-4307 | UP/Q9QXX2 | denotes | feron gamma (IFN |
| T2755 | 5062-5072 | UMLS/C0021467 | denotes | tion in RA |
| T2754 | 4595-4605 | UMLS/C0021467 | denotes | tion of T- |
| T2753 | 1457-1467 | UMLS/C0021467 | denotes | inhibition |
| T2752 | 2576-2586 | UMLS/C0284447 | denotes | imulating |
| T2751 | 5062-5072 | UMLS/C0021469 | denotes | tion in RA |
| T2750 | 4877-4887 | UMLS/C0021469 | denotes | ting the C |
| T2749 | 4595-4605 | UMLS/C0021469 | denotes | tion of T- |
| T2748 | 1457-1467 | UMLS/C0021469 | denotes | inhibition |
| T2747 | 85-95 | UMLS/C0021469 | denotes | inhibiting |
| T2746 | 3013-3025 | UMLS/C0205412 | denotes | nsufficient |
| T2745 | 2127-2154 | UMLS/C1456820 | denotes | Tumor necrosis factor alpha |
| T2744 | 5161-5169 | UMLS/C0150312 | denotes | e of IL- |
| T2743 | 3469-3477 | UMLS/C0150312 | denotes | esence o |
| T2742 | 2793-2800 | UMLS/C0150312 | denotes | resent |
| T2741 | 2397-2406 | UP/P63127 | denotes | roteases, |
| T2740 | 4291-4307 | UP/Q4ZH68 | denotes | feron gamma (IFN |
| T2739 | 4057-4060 | UMLS/C0205388 | denotes | n n |
| T2738 | 1384-1403 | UMLS/C0678613 | denotes | feedback inhibition |
| T2737 | 3616-3627 | UMLS/C2699427 | denotes | nction with |
| T2736 | 4291-4307 | UP/A4PIZ9 | denotes | feron gamma (IFN |
| T2735 | 4567-4573 | UMLS/C1553875 | denotes | disea |
| T2734 | 4650-4659 | UMLS/C1511636 | denotes | xic T-cel |
| T2733 | 1568-1573 | UMLS/C0032214 | denotes | plays |
| T2732 | 3414-3423 | UMLS/C0442797 | denotes | creased i |
| T2731 | 4339-4347 | UMLS/C1883712 | denotes | on, CD4+ |
| T2730 | 3091-3099 | UMLS/C1883712 | denotes | ddition, |
| T2729 | 1540-1547 | UMLS/C0557651 | denotes | studies |
| T2728 | 981-988 | UMLS/C0557651 | denotes | Studies |
| T2727 | 4499-4503 | UMLS/C1705809 | denotes | n RA |
| T2726 | 1580-1584 | UMLS/C1705809 | denotes | role |
| T2725 | 1421-1426 | UMLS/C1705809 | denotes | roles |
| T2724 | 1480-1498 | UMLS/C1511617 | denotes | cytokine signaling |
| T2723 | 4840-4848 | UMLS/C0205369 | denotes | ic T-cel |
| T2722 | 1002-1010 | UMLS/C0205369 | denotes | specific |
| T2721 | 4499-4503 | UMLS/C1705812 | denotes | n RA |
| T2720 | 1580-1584 | UMLS/C1705812 | denotes | role |
| T2719 | 1421-1426 | UMLS/C1705812 | denotes | roles |
| T2718 | 2288-2292 | UMLS/C1550718 | denotes | ive |
| T2717 | 4499-4503 | UMLS/C1705810 | denotes | n RA |
| T2716 | 1580-1584 | UMLS/C1705810 | denotes | role |
| T2715 | 1421-1426 | UMLS/C1705810 | denotes | roles |
| T2714 | 4499-4503 | UMLS/C1705811 | denotes | n RA |
| T2713 | 1580-1584 | UMLS/C1705811 | denotes | role |
| T2712 | 1421-1426 | UMLS/C1705811 | denotes | roles |
| T2711 | 3489-3493 | UMLS/C1522428 | denotes | 1, a |
| T2710 | 3341-3345 | UMLS/C1522428 | denotes | -1 a |
| T2709 | 2168-2172 | UMLS/C1522428 | denotes | L-1, |
| T2708 | 2920-2924 | UMLS/C1522427 | denotes | est |
| T2707 | 3170-3175 | UMLS/C0456079 | denotes | evel |
| T2706 | 3004-3009 | UMLS/C0456079 | denotes | evel |
| T2705 | 3732-3741 | UMLS/C0183683 | denotes | rted by t |
| T2704 | 2397-2406 | UP/P63125 | denotes | roteases, |
| T2703 | 5285-5301 | UMLS/C0229664 | denotes | ral blood (PB) C |
| T2702 | 4190-4195 | UMLS/C1704970 | denotes | of c |
| T2701 | 4464-4468 | UMLS/C1546560 | denotes | estr |
| T2700 | 1212-1221 | UMLS/C0162638 | denotes | apoptosis |
| T2699 | 3489-3493 | UMLS/C1149212 | denotes | 1, a |
| T2698 | 3341-3345 | UMLS/C1149212 | denotes | -1 a |
| T2697 | 2168-2172 | UMLS/C1149212 | denotes | L-1, |
| T2696 | 3013-3025 | UMLS/C0231180 | denotes | nsufficient |
| T2695 | 5232-5237 | UMLS/C1149215 | denotes | and t |
| T2694 | 5173-5178 | UMLS/C1149215 | denotes | the i |
| T2693 | 4803-4808 | UMLS/C1149215 | denotes | effic |
| T2692 | 3228-3233 | UMLS/C1149215 | denotes | L-10 |
| T2691 | 3133-3138 | UMLS/C1149215 | denotes | L-10 |
| T2690 | 2835-2840 | UMLS/C1149215 | denotes | L-10, |
| T2689 | 1721-1726 | UMLS/C1149215 | denotes | IL-10 |
| T2688 | 1623-1628 | UMLS/C1149215 | denotes | IL-10 |
| T2687 | 1082-1087 | UMLS/C1149215 | denotes | IL-10 |
| T2686 | 901-906 | UMLS/C1149215 | denotes | IL-10 |
| T2685 | 539-544 | UMLS/C1149215 | denotes | IL-10 |
| T2684 | 366-371 | UMLS/C1149215 | denotes | IL-10 |
| T2683 | 154-165 | UMLS/C1149215 | denotes | IL-10 binds |
| T2682 | 13-18 | UMLS/C1149215 | denotes | IL-10 |
| T2681 | 2397-2406 | UP/P21407 | denotes | roteases, |
| T2680 | 4499-4503 | UMLS/C0035820 | denotes | n RA |
| T2679 | 1580-1584 | UMLS/C0035820 | denotes | role |
| T2678 | 1421-1426 | UMLS/C0035820 | denotes | roles |
| T2677 | 3170-3175 | UMLS/C0441889 | denotes | evel |
| T2676 | 3004-3009 | UMLS/C0441889 | denotes | evel |
| T2675 | 4667-4677 | UMLS/C1706221 | denotes | ated antig |
| T2674 | 5020-5030 | UMLS/C1522618 | denotes | ance of CD |
| T2673 | 784-791 | UMLS/C1637379 | denotes | rapidly |
| T2672 | 2397-2406 | UP/P63131 | denotes | roteases, |
| T2671 | 5083-5095 | UMLS/C1292732 | denotes | igated the p |
| T2670 | 1568-1573 | UMLS/C0600138 | denotes | plays |
| T2669 | 3786-3794 | UMLS/C0122040 | denotes | RB1*0404 |
| T2668 | 2293-2297 | UMLS/C0035853 | denotes | ise |
| T2667 | 2456-2460 | UMLS/C1149241 | denotes | L-6 |
| T2666 | 1692-1696 | UMLS/C1149241 | denotes | IL-6 |
| T2665 | 1633-1637 | UMLS/C1149241 | denotes | IL-6 |
| T2664 | 1184-1188 | UMLS/C1149241 | denotes | IL-6 |
| T2663 | 937-941 | UMLS/C1149241 | denotes | IL-6 |
| T2662 | 5197-5202 | UMLS/C1335872 | denotes | nd ST |
| T2661 | 726-731 | UMLS/C1335872 | denotes | STAT1 |
| T2660 | 693-698 | UMLS/C1335872 | denotes | STAT1 |
| T2659 | 4291-4307 | UP/P42162 | denotes | feron gamma (IFN |
| T2658 | 4464-4468 | UMLS/C0391978 | denotes | estr |
| T2657 | 5247-5257 | UMLS/C0185117 | denotes | ion of SOC |
| T2656 | 3890-3900 | UMLS/C0185117 | denotes | ssion of M |
| T2655 | 3389-3399 | UMLS/C0185117 | denotes | pression o |
| T2654 | 2993-3003 | UMLS/C0185117 | denotes | xpression |
| T3233 | 813-820 | UMLS/C0007610 | denotes | nucleus |
| T3232 | 4977-5001 | UMLS/C0003315 | denotes | n-presenting cells. To e |
| T3231 | 3350-3366 | UMLS/C0003313 | denotes | mune complexes [ |
| T3230 | 5050-5054 | UMLS/C0323983 | denotes | irec |
| T3229 | 3699-3703 | UMLS/C0323983 | denotes | auto |
| T3228 | 2827-2833 | UMLS/C0444497 | denotes | oints. |
| T3227 | 2260-2265 | UMLS/C0444497 | denotes | oint |
| T3226 | 4190-4195 | UMLS/C0444504 | denotes | of c |
| T3225 | 5100-5110 | UMLS/C1548180 | denotes | tion of IF |
| T3224 | 4385-4395 | UMLS/C1548180 | denotes | tion of au |
| T3223 | 100-110 | UMLS/C1548180 | denotes | production |
| T3222 | 1115-1124 | UMLS/C1114821 | denotes | reactions |
| T3221 | 4832-4839 | UMLS/C0003320 | denotes | n-speci |
| T3220 | 3603-3611 | UMLS/C0003320 | denotes | ens, in |
| T3219 | 1434-1443 | UMLS/C1363844 | denotes | mediators |
| T3218 | 351-362 | UMLS/C1546938 | denotes | interaction |
| T3217 | 2696-2716 | UMLS/C0007589 | denotes | ell differentiation |
| T3216 | 2397-2406 | UMLS/C0030940 | denotes | roteases, |
| T3215 | 1588-1598 | UMLS/C0851285 | denotes | regulating |
| T3214 | 40-50 | UMLS/C0851285 | denotes | regulating |
| T3213 | 1369-1372 | UMLS/C1551336 | denotes | act |
| T3212 | 2397-2406 | UMLS/C0030946 | denotes | roteases, |
| T3211 | 2224-2231 | UMLS/C1184743 | denotes | rocess |
| T3210 | 2810-2820 | UMLS/C1265611 | denotes | uantities |
| T3209 | 4291-4307 | UP/Q62574 | denotes | feron gamma (IFN |
| T3208 | 5121-5126 | UMLS/C0231290 | denotes | D3 an |
| T3207 | 5271-5276 | UMLS/C1426212 | denotes | RNA i |
| T3206 | 1562-1567 | UMLS/C1426212 | denotes | SOCS3 |
| T3205 | 1317-1323 | UMLS/C1555907 | denotes | family |
| T3204 | 414-420 | UMLS/C1555907 | denotes | family |
| T3203 | 3029-3043 | UMLS/C1707527 | denotes | ounterbalance |
| T3202 | 251-265 | UMLS/C1517880 | denotes | ligand-binding |
| T3201 | 5135-5139 | UMLS/C1426202 | denotes | stim |
| T3200 | 4892-4896 | UMLS/C1426202 | denotes | igna |
| T3199 | 4735-4739 | UMLS/C1426202 | denotes | n T |
| T3198 | 3936-3940 | UMLS/C1426202 | denotes | liga |
| T3197 | 3633-3637 | UMLS/C1426202 | denotes | medi |
| T3196 | 4119-4130 | UMLS/C0024432 | denotes | phages and |
| T3195 | 3259-3270 | UMLS/C0024432 | denotes | acrophages |
| T3194 | 2959-2969 | UMLS/C0024432 | denotes | acrophage |
| T3193 | 2854-2865 | UMLS/C0024432 | denotes | acrophages |
| T3192 | 2036-2047 | UMLS/C0024432 | denotes | macrophages |
| T3191 | 1876-1887 | UMLS/C0024432 | denotes | macrophages |
| T3190 | 1128-1139 | UMLS/C0024432 | denotes | macrophages |
| T3189 | 3732-3741 | UMLS/C0344211 | denotes | rted by t |
| T3188 | 751-755 | UMLS/C0013058 | denotes | form |
| T3187 | 4291-4307 | UP/P63311 | denotes | feron gamma (IFN |
| T3186 | 1966-1971 | UMLS/C0007634 | denotes | cells |
| T3185 | 5261-5266 | UMLS/C1426208 | denotes | nd SO |
| T3184 | 2362-2372 | UMLS/C0282554 | denotes | hemokines, |
| T3183 | 4135-4143 | UMLS/C1550315 | denotes | ial fibr |
| T3182 | 2052-2060 | UMLS/C1550315 | denotes | synovial |
| T3181 | 1941-1949 | UMLS/C1550315 | denotes | synovial |
| T3180 | 4242-4249 | UMLS/C0439180 | denotes | se of p |
| T3179 | 4444-4454 | UMLS/C0029431 | denotes | last-media |
| T3178 | 4242-4249 | UMLS/C0680255 | denotes | se of p |
| T3177 | 681-685 | UMLS/C1366753 | denotes | STAT |
| T3176 | 631-679 | UMLS/C1366753 | denotes | signal transducer and activator of transcription |
| T3175 | 4291-4307 | UP/P07353 | denotes | feron gamma (IFN |
| T3174 | 1198-1208 | UMLS/C1708528 | denotes | prevention |
| T3173 | 1317-1323 | UMLS/C1552262 | denotes | family |
| T3172 | 414-420 | UMLS/C1552262 | denotes | family |
| T3171 | 1115-1124 | UMLS/C0443286 | denotes | reactions |
| T3170 | 4291-4307 | UP/Q647G2 | denotes | feron gamma (IFN |
| T3169 | 4291-4307 | UP/Q865Y4 | denotes | feron gamma (IFN |
| T3168 | 2390-2396 | UMLS/C1706515 | denotes | atrix |
| T3167 | 4789-4796 | UMLS/C1510996 | denotes | y [23]. |
| T3166 | 4291-4307 | UP/Q5CCK0 | denotes | feron gamma (IFN |
| T3165 | 197-204 | UMLS/C1704241 | denotes | complex |
| T3164 | 4291-4307 | UP/P28341 | denotes | feron gamma (IFN |
| T3163 | 2804-2809 | UMLS/C1704243 | denotes | arge |
| T3162 | 1863-1874 | UMLS/C0024264 | denotes | lymphocytes |
| T3161 | 4090-4100 | UMLS/C0443318 | denotes | ining the |
| T3160 | 4422-4439 | UMLS/C0035448 | denotes | toid factor and o |
| T3159 | 2804-2809 | UMLS/C0443228 | denotes | arge |
| T3158 | 4707-4710 | UMLS/C0344312 | denotes | ock |
| T3157 | 4362-4367 | UMLS/C0344312 | denotes | stimu |
| T3156 | 1365-1368 | UMLS/C0344312 | denotes | can |
| T3155 | 1317-1323 | UMLS/C2700055 | denotes | family |
| T3154 | 414-420 | UMLS/C2700055 | denotes | family |
| T3153 | 5197-5202 | UP/P42224 | denotes | nd ST |
| T3152 | 726-731 | UP/P42224 | denotes | STAT1 |
| T3151 | 1580-1584 | UMLS/C1704326 | denotes | role |
| T3150 | 1421-1426 | UMLS/C1704326 | denotes | roles |
| T3149 | 1144-1155 | UMLS/C0948762 | denotes | neutrophils |
| T3148 | 2184-2203 | UMLS/C0598896 | denotes | acrophage products, |
| T3147 | 3427-3441 | UMLS/C0039097 | denotes | novial fluid d |
| T3146 | 1738-1755 | UMLS/C0039099 | denotes | synovial membrane |
| T3145 | 4510-4519 | UMLS/C0039103 | denotes | tis was r |
| T3144 | 4064-4070 | UMLS/C0449788 | denotes | r, may |
| T3143 | 1973-1981 | UMLS/C0439064 | denotes | Numerous |
| T3142 | 5127-5130 | UMLS/C2698592 | denotes | CD |
| T3141 | 3704-3722 | UMLS/C0443146 | denotes | mmune process has |
| T3140 | 2288-2292 | UMLS/C1442162 | denotes | ive |
| T3139 | 2362-2372 | UMLS/C1527036 | denotes | hemokines, |
| T3138 | 3513-3549 | UMLS/C0079784 | denotes | phage colony-stimulating factor [15] |
| T3137 | 1788-1801 | UMLS/C1880022 | denotes | characterized |
| T3136 | 4965-4973 | UMLS/C1705273 | denotes | on of an |
| T3135 | 2657-2666 | UMLS/C1705273 | denotes | unctions, |
| T3134 | 115-123 | UMLS/C1705273 | denotes | function |
| T3133 | 3723-3726 | UMLS/C2348947 | denotes | een |
| T3132 | 4291-4307 | UP/Q25BC0 | denotes | feron gamma (IFN |
| T3131 | 1276-1290 | UMLS/C1564682 | denotes | SOCS) proteins |
| T3130 | 4291-4307 | UP/P01580 | denotes | feron gamma (IFN |
| T3129 | 5312-5319 | UMLS/C0039194 | denotes | from R |
| T3128 | 5039-5046 | UMLS/C0039194 | denotes | s to th |
| T3127 | 4849-4855 | UMLS/C0039194 | denotes | cytok |
| T3126 | 4743-4750 | UMLS/C0039194 | denotes | s by bi |
| T3125 | 4660-4666 | UMLS/C0039194 | denotes | -assoc |
| T3124 | 4354-4361 | UMLS/C0039194 | denotes | s could |
| T3123 | 4036-4043 | UMLS/C0039194 | denotes | ls, eve |
| T3122 | 3561-3568 | UMLS/C0039194 | denotes | ls may |
| T3121 | 2880-2887 | UMLS/C0039194 | denotes | cells |
| T3120 | 2650-2656 | UMLS/C0039194 | denotes | -cell |
| T3119 | 1225-1232 | UMLS/C0039194 | denotes | T cells |
| T3118 | 4765-4769 | UMLS/C1366561 | denotes | nd C |
| T3117 | 693-698 | UP/P42224 | denotes | STAT1 |
| T3116 | 4965-4973 | UMLS/C0542341 | denotes | on of an |
| T3115 | 2657-2666 | UMLS/C0542341 | denotes | unctions, |
| T3114 | 115-123 | UMLS/C0542341 | denotes | function |
| T2653 | 2397-2406 | UP/P63120 | denotes | roteases, |
| T2652 | 4291-4307 | UP/P17773 | denotes | feron gamma (IFN |
| T2651 | 513-519 | UMLS/C1149187 | denotes | IL-10R |
| T2650 | 376-382 | UMLS/C1149187 | denotes | IL-10R |
| T2649 | 335-341 | UMLS/C1149187 | denotes | IL-10R |
| T2648 | 283-289 | UMLS/C1149187 | denotes | IL-10R |
| T2647 | 189-195 | UMLS/C1149187 | denotes | IL-10R |
| T2646 | 2397-2406 | UP/P51518 | denotes | roteases, |
| T2645 | 942-949 | UMLS/C1711343 | denotes | derived |
| T2644 | 907-914 | UMLS/C1711343 | denotes | derived |
| T2643 | 4105-4115 | UMLS/C1879547 | denotes | ation of m |
| T2642 | 4021-4030 | UMLS/C1879547 | denotes | ated CD4+ |
| T2641 | 3576-3585 | UMLS/C1879547 | denotes | ated by a |
| T2640 | 2513-2522 | UMLS/C1879547 | denotes | ctivated |
| T2639 | 1670-1680 | UMLS/C1879547 | denotes | activation |
| T2638 | 1054-1064 | UMLS/C1879547 | denotes | activation |
| T2637 | 582-592 | UMLS/C1879547 | denotes | activation |
| T2636 | 2397-2406 | UP/P10265 | denotes | roteases, |
| T2635 | 4291-4307 | UP/O57608 | denotes | feron gamma (IFN |
| T2634 | 1317-1323 | UMLS/C0015576 | denotes | family |
| T2633 | 414-420 | UMLS/C0015576 | denotes | family |
| T2632 | 1540-1547 | UMLS/C0008972 | denotes | studies |
| T2631 | 981-988 | UMLS/C0008972 | denotes | Studies |
| T2630 | 1540-1547 | UMLS/C0008976 | denotes | studies |
| T2629 | 981-988 | UMLS/C0008976 | denotes | Studies |
| T2628 | 2224-2231 | UMLS/C1550044 | denotes | rocess |
| T2627 | 4291-4307 | UP/O57603 | denotes | feron gamma (IFN |
| T2626 | 2456-2460 | UMLS/C1527132 | denotes | L-6 |
| T2625 | 1692-1696 | UMLS/C1527132 | denotes | IL-6 |
| T2624 | 1633-1637 | UMLS/C1527132 | denotes | IL-6 |
| T2623 | 1184-1188 | UMLS/C1527132 | denotes | IL-6 |
| T2622 | 937-941 | UMLS/C1527132 | denotes | IL-6 |
| T2897 | 3569-3572 | UMLS/C0337876 | denotes | e a |
| T2896 | 4291-4307 | UP/Q7TSP4 | denotes | feron gamma (IFN |
| T2895 | 4291-4307 | UP/Q8SPW9 | denotes | feron gamma (IFN |
| T2894 | 4399-4413 | UMLS/C0004358 | denotes | tibodies such |
| T2893 | 4745-4761 | UMLS/C0699040 | denotes | by binding to CD |
| T2892 | 4199-4211 | UMLS/C0699040 | denotes | surface CD69 |
| T2891 | 4164-4176 | UMLS/C0699040 | denotes | surface sign |
| T2890 | 3376-3388 | UMLS/C0699040 | denotes | ll surface e |
| T2889 | 2568-2575 | UMLS/C0332257 | denotes | nclude |
| T2888 | 2322-2331 | UMLS/C0332257 | denotes | ncluding |
| T2887 | 942-949 | UMLS/C1441547 | denotes | derived |
| T2886 | 907-914 | UMLS/C1441547 | denotes | derived |
| T2885 | 1404-1409 | UMLS/C0445022 | denotes | loops |
| T2884 | 3683-3695 | UMLS/C0237881 | denotes | ficance of t |
| T2883 | 600-606 | UMLS/C0205275 | denotes | latent |
| T2882 | 4667-4677 | UMLS/C0332281 | denotes | ated antig |
| T2881 | 478-493 | UMLS/C0332281 | denotes | associated with |
| T2880 | 1701-1704 | UMLS/C1518422 | denotes | not |
| T2879 | 2974-2983 | UMLS/C0242632 | denotes | h1 cells, |
| T2878 | 4291-4307 | UP/P63309 | denotes | feron gamma (IFN |
| T2877 | 4840-4848 | UMLS/C1552740 | denotes | ic T-cel |
| T2876 | 1002-1010 | UMLS/C1552740 | denotes | specific |
| T2875 | 4045-4049 | UMLS/C0587117 | denotes | thou |
| T2874 | 4064-4070 | UMLS/C0237753 | denotes | r, may |
| T2873 | 4291-4307 | UP/P46402 | denotes | feron gamma (IFN |
| T2872 | 2568-2575 | UMLS/C2700399 | denotes | nclude |
| T2871 | 2322-2331 | UMLS/C2700399 | denotes | ncluding |
| T2870 | 5184-5193 | UMLS/C0205263 | denotes | on of STA |
| T2869 | 1710-1717 | UMLS/C0205263 | denotes | induced |
| T2868 | 1681-1688 | UMLS/C0205263 | denotes | induced |
| T2867 | 545-552 | UMLS/C0205263 | denotes | induces |
| T2866 | 4378-4384 | UMLS/C0004561 | denotes | produ |
| T2865 | 2613-2619 | UMLS/C0004561 | denotes | -cell |
| T2864 | 4784-4788 | UMLS/C0205250 | denotes | vidi |
| T2863 | 2310-2320 | UMLS/C0449432 | denotes | omponents, |
| T2862 | 318-327 | UMLS/C0449432 | denotes | component |
| T2861 | 266-275 | UMLS/C0449432 | denotes | component |
| T2860 | 4422-4439 | UP/P04207 | denotes | toid factor and o |
| T2859 | 1198-1208 | UMLS/C2700409 | denotes | prevention |
| T2858 | 4177-4186 | UMLS/C1710082 | denotes | ling by m |
| T2857 | 3661-3670 | UMLS/C1710082 | denotes | ling, in |
| T2856 | 3234-3243 | UMLS/C1710082 | denotes | ignaling |
| T2855 | 2397-2406 | UP/P10271 | denotes | roteases, |
| T2854 | 2397-2406 | UP/P63119 | denotes | roteases, |
| T2853 | 3941-3948 | UMLS/C1749457 | denotes | ds, CD8 |
| T2852 | 2016-2030 | UMLS/C0574941 | denotes | inflamed joint |
| T2851 | 4765-4769 | UMLS/C0104998 | denotes | nd C |
| T2850 | 3950-3954 | UMLS/C0104998 | denotes | and |
| T2849 | 4144-4155 | UMLS/C0016030 | denotes | blasts thro |
| T2848 | 2523-2534 | UMLS/C0016030 | denotes | ibroblasts, |
| T2847 | 2061-2072 | UMLS/C0016030 | denotes | fibroblasts |
| T2846 | 1950-1960 | UMLS/C0016030 | denotes | fibroblast |
| T2845 | 2793-2800 | UMLS/C0449450 | denotes | resent |
| T2844 | 3786-3794 | UMLS/C1415576 | denotes | RB1*0404 |
| T2843 | 1068-1077 | UMLS/C0205224 | denotes | essential |
| T2842 | 4632-4646 | UMLS/C0162768 | denotes | protein of cy |
| T2841 | 5184-5193 | UMLS/C1621983 | denotes | on of STA |
| T2840 | 1327-1337 | UMLS/C0205227 | denotes | endogenous |
| T2839 | 243-250 | UMLS/C0205225 | denotes | primary |
| T2838 | 942-949 | UMLS/C2348040 | denotes | derived |
| T2621 | 1301-1311 | UMLS/C1550043 | denotes | identified |
| T2620 | 1342-1359 | UMLS/C1152564 | denotes | kinase inhibitors |
| T2619 | 4291-4307 | UP/Q2PE75 | denotes | feron gamma (IFN |
| T2618 | 681-685 | UMLS/C0205548 | denotes | STAT |
| T2603 | 51-73 | UMLS/C1155266 | denotes | inflammatory responses |
| T2602 | 5232-5237 | UMLS/C1522550 | denotes | and t |
| T2601 | 5173-5178 | UMLS/C1522550 | denotes | the i |
| T2600 | 4803-4808 | UMLS/C1522550 | denotes | effic |
| T2599 | 3228-3233 | UMLS/C1522550 | denotes | L-10 |
| T2598 | 3133-3138 | UMLS/C1522550 | denotes | L-10 |
| T2597 | 2835-2840 | UMLS/C1522550 | denotes | L-10, |
| T2596 | 1721-1726 | UMLS/C1522550 | denotes | IL-10 |
| T2595 | 1623-1628 | UMLS/C1522550 | denotes | IL-10 |
| T2594 | 1082-1087 | UMLS/C1522550 | denotes | IL-10 |
| T2593 | 901-906 | UMLS/C1522550 | denotes | IL-10 |
| T2592 | 539-544 | UMLS/C1522550 | denotes | IL-10 |
| T2591 | 366-371 | UMLS/C1522550 | denotes | IL-10 |
| T2590 | 13-18 | UMLS/C1522550 | denotes | IL-10 |
| T2589 | 5121-5126 | UMLS/C0687676 | denotes | D3 an |
| T2588 | 5232-5237 | UMLS/C1334098 | denotes | and t |
| T2587 | 5173-5178 | UMLS/C1334098 | denotes | the i |
| T2586 | 4803-4808 | UMLS/C1334098 | denotes | effic |
| T2585 | 3228-3233 | UMLS/C1334098 | denotes | L-10 |
| T2584 | 3133-3138 | UMLS/C1334098 | denotes | L-10 |
| T2583 | 2835-2840 | UMLS/C1334098 | denotes | L-10, |
| T2582 | 1721-1726 | UMLS/C1334098 | denotes | IL-10 |
| T2581 | 1623-1628 | UMLS/C1334098 | denotes | IL-10 |
| T2580 | 1082-1087 | UMLS/C1334098 | denotes | IL-10 |
| T2579 | 901-906 | UMLS/C1334098 | denotes | IL-10 |
| T2578 | 539-544 | UMLS/C1334098 | denotes | IL-10 |
| T2577 | 366-371 | UMLS/C1334098 | denotes | IL-10 |
| T2576 | 13-18 | UMLS/C1334098 | denotes | IL-10 |
| T2575 | 1910-1918 | UMLS/C1883357 | denotes | together |
| T2574 | 1404-1409 | UMLS/C1881441 | denotes | loops |
| T2573 | 4291-4307 | UP/Q866Y6 | denotes | feron gamma (IFN |
| T2572 | 4856-4864 | UMLS/C1524094 | denotes | ne respo |
| T2571 | 4273-4282 | UMLS/C1524094 | denotes | ines such |
| T2570 | 3312-3321 | UMLS/C1524094 | denotes | ytokines |
| T2569 | 2764-2772 | UMLS/C1524094 | denotes | ytokine |
| T2568 | 2750-2759 | UMLS/C1524094 | denotes | ytokines |
| T2567 | 2478-2486 | UMLS/C1524094 | denotes | ytokine |
| T2566 | 2351-2360 | UMLS/C1524094 | denotes | ytokines, |
| T2565 | 2116-2125 | UMLS/C1524094 | denotes | cytokines |
| T2564 | 1982-1991 | UMLS/C1524094 | denotes | cytokines |
| T2563 | 143-152 | UMLS/C1524094 | denotes | cytokines |
| T2562 | 28-36 | UMLS/C1524094 | denotes | cytokine |
| T2561 | 3513-3549 | UMLS/C1524095 | denotes | phage colony-stimulating factor [15] |
| T2560 | 4784-4788 | UMLS/C1561957 | denotes | vidi |
| T2559 | 1342-1359 | UMLS/C1171350 | denotes | kinase inhibitors |
| T2558 | 4784-4788 | UMLS/C1561958 | denotes | vidi |
| T2557 | 1808-1818 | UMLS/C1546677 | denotes | infiltrate |
| T2556 | 2456-2460 | UMLS/C0021760 | denotes | L-6 |
| T2555 | 1692-1696 | UMLS/C0021760 | denotes | IL-6 |
| T2554 | 1633-1637 | UMLS/C0021760 | denotes | IL-6 |
| T2553 | 1184-1188 | UMLS/C0021760 | denotes | IL-6 |
| T2552 | 937-941 | UMLS/C0021760 | denotes | IL-6 |
| T2551 | 4291-4307 | UP/Q5I6S9 | denotes | feron gamma (IFN |
| T2550 | 3048-3055 | UMLS/C1707310 | denotes | ascade |
| T2549 | 2397-2406 | UP/P63123 | denotes | roteases, |
| T2548 | 4291-4307 | UP/Q865W6 | denotes | feron gamma (IFN |
| T2547 | 4321-4326 | UMLS/C1522571 | denotes | [21,2 |
| T2546 | 5161-5169 | UMLS/C0392148 | denotes | e of IL- |
| T2545 | 3469-3477 | UMLS/C0392148 | denotes | esence o |
| T2544 | 4291-4307 | UP/P17803 | denotes | feron gamma (IFN |
| T2543 | 2456-2460 | UMLS/C1334122 | denotes | L-6 |
| T2542 | 1692-1696 | UMLS/C1334122 | denotes | IL-6 |
| T2541 | 1633-1637 | UMLS/C1334122 | denotes | IL-6 |
| T2540 | 1184-1188 | UMLS/C1334122 | denotes | IL-6 |
| T2539 | 937-941 | UMLS/C1334122 | denotes | IL-6 |
| T2538 | 1576-1579 | UMLS/C1706198 | denotes | key |
| T2537 | 24-27 | UMLS/C1706198 | denotes | key |
| T2536 | 3489-3493 | UMLS/C0021755 | denotes | 1, a |
| T2535 | 3341-3345 | UMLS/C0021755 | denotes | -1 a |
| T2534 | 2168-2172 | UMLS/C0021755 | denotes | L-1, |
| T2533 | 3489-3493 | UMLS/C0021753 | denotes | 1, a |
| T2532 | 3341-3345 | UMLS/C0021753 | denotes | -1 a |
| T2531 | 2168-2172 | UMLS/C0021753 | denotes | L-1, |
| T2530 | 681-685 | UMLS/C1335960 | denotes | STAT |
| T2529 | 2672-2700 | UMLS/C1268005 | denotes | ematopoietic precursor cell |
| T2528 | 4291-4307 | UMLS/C0021740 | denotes | feron gamma (IFN |
| T2527 | 1198-1208 | UMLS/C0199176 | denotes | prevention |
| T2526 | 3904-3926 | UMLS/C0019630 | denotes | lass II molecules and |
| T2525 | 3764-3785 | UMLS/C0019630 | denotes | lass II antigens HLA- |
| T2524 | 4291-4307 | UMLS/C0021745 | denotes | feron gamma (IFN |
| T2523 | 4291-4307 | UP/Q9TTB0 | denotes | feron gamma (IFN |
| T2522 | 681-685 | UMLS/C1420304 | denotes | STAT |
| T2521 | 351-362 | UMLS/C0687133 | denotes | interaction |
| T2520 | 5247-5257 | UMLS/C0017262 | denotes | ion of SOC |
| T2519 | 3890-3900 | UMLS/C0017262 | denotes | ssion of M |
| T2518 | 3389-3399 | UMLS/C0017262 | denotes | pression o |
| T2517 | 2993-3003 | UMLS/C0017262 | denotes | xpression |
| T2516 | 5127-5130 | UMLS/C0108779 | denotes | CD |
| T2515 | 2332-2337 | UMLS/C1556044 | denotes | ther |
| T2514 | 4821-4827 | UMLS/C1706084 | denotes | the a |
| T2513 | 4711-4716 | UMLS/C1706084 | denotes | the e |
| T2512 | 1655-1663 | UMLS/C1706084 | denotes | blocking |
| T2511 | 2895-2910 | UMLS/C1267208 | denotes | ynovial tissue |
| T2510 | 4064-4070 | UMLS/C1709287 | denotes | r, may |
| T2509 | 2374-2388 | UP/Q6RZT5 | denotes | rowth factors, |
| T2508 | 4212-4216 | UMLS/C0108800 | denotes | and |
| T2507 | 4609-4626 | UMLS/C1155065 | denotes | activation with |
| T2506 | 2773-2783 | UMLS/C0243077 | denotes | nhibitors |
| T2505 | 2374-2388 | UP/P20494 | denotes | rowth factors, |
| T2504 | 4554-4563 | UMLS/C1705169 | denotes | ent of ac |
| T2503 | 4821-4827 | UMLS/C1533157 | denotes | the a |
| T2502 | 4711-4716 | UMLS/C1533157 | denotes | the e |
| T2501 | 1655-1663 | UMLS/C1533157 | denotes | blocking |
| T2500 | 3941-3948 | UMLS/C0023688 | denotes | ds, CD8 |
| T2499 | 1540-1547 | UMLS/C1880229 | denotes | studies |
| T2498 | 981-988 | UMLS/C1880229 | denotes | Studies |
| T2497 | 1824-1831 | UMLS/C1883525 | denotes | variety |
| T2496 | 3123-3129 | UMLS/C1552007 | denotes | ction |
| T2495 | 2560-2567 | UMLS/C1552007 | denotes | ctions |
| T2494 | 1613-1619 | UMLS/C1552007 | denotes | action |
| T2493 | 2310-2320 | UMLS/C1548799 | denotes | omponents, |
| T2492 | 318-327 | UMLS/C1548799 | denotes | component |
| T2491 | 266-275 | UMLS/C1548799 | denotes | component |
| T2490 | 3105-3122 | UMLS/C1515999 | denotes | nti-inflammatory |
| T2489 | 2732-2749 | UMLS/C1515999 | denotes | nti-inflammatory |
| T2488 | 1097-1114 | UMLS/C1515999 | denotes | anti-inflammatory |
| T2487 | 915-932 | UMLS/C1515999 | denotes | anti-inflammatory |
| T2486 | 4291-4307 | UP/P30123 | denotes | feron gamma (IFN |
| T2485 | 4291-4307 | UP/O35497 | denotes | feron gamma (IFN |
| T2484 | 4242-4249 | UMLS/C1283071 | denotes | se of p |
| T2483 | 4533-4539 | UMLS/C0700164 | denotes | by su |
| T2482 | 1924-1937 | UMLS/C0334094 | denotes | proliferation |
| T2481 | 2374-2388 | UP/O57166 | denotes | rowth factors, |
| T2480 | 4554-4563 | UMLS/C0039798 | denotes | ent of ac |
| T2479 | 2985-2988 | UMLS/C0005341 | denotes | ut |
| T2478 | 1697-1700 | UMLS/C0005341 | denotes | but |
| T2477 | 1411-1414 | UMLS/C0005341 | denotes | but |
| T2476 | 1161-1164 | UMLS/C0005341 | denotes | but |
| T2475 | 5047-5049 | UMLS/C0319022 | denotes | s |
| T2474 | 5003-5005 | UMLS/C0319022 | denotes | ci |
| T2473 | 4762-4764 | UMLS/C0319022 | denotes | 0 |
| T2472 | 3462-3464 | UMLS/C0319022 | denotes | t |
| T2471 | 3147-3149 | UMLS/C0319022 | denotes | o |
| T2470 | 3026-3028 | UMLS/C0319022 | denotes | o |
| T2469 | 2298-2300 | UMLS/C0319022 | denotes | o |
| T2468 | 166-168 | UMLS/C0319022 | denotes | to |
| T2467 | 4455-4463 | UMLS/C0127400 | denotes | ed bone |
| T2466 | 3638-3646 | UMLS/C0127400 | denotes | ted cost |
| T2465 | 1088-1096 | UMLS/C0127400 | denotes | mediated |
| T2464 | 4821-4827 | UMLS/C0028778 | denotes | the a |
| T2463 | 4711-4716 | UMLS/C0028778 | denotes | the e |
| T2462 | 1655-1663 | UMLS/C0028778 | denotes | blocking |
| T2461 | 2374-2388 | UP/P08072 | denotes | rowth factors, |
| T2460 | 4291-4307 | UP/P42161 | denotes | feron gamma (IFN |
| T2459 | 5277-5281 | UMLS/C0035696 | denotes | per |
| T2458 | 2620-2630 | UMLS/C1254042 | denotes | aturation |
| T2457 | 4821-4827 | UMLS/C0233660 | denotes | the a |
| T2456 | 4711-4716 | UMLS/C0233660 | denotes | the e |
| T2455 | 1655-1663 | UMLS/C0233660 | denotes | blocking |
| T2454 | 4721-4731 | UMLS/C0425152 | denotes | ment of CD |
| T2453 | 383-390 | UMLS/C0425152 | denotes | engages |
| T2452 | 4533-4539 | UMLS/C0456369 | denotes | by su |
| T2451 | 1242-1274 | UP/Q9NSE2 | denotes | suppressor of cytokine signaling |
| T2450 | 1540-1547 | UMLS/C0947630 | denotes | studies |
| T2449 | 981-988 | UMLS/C0947630 | denotes | Studies |
| T2448 | 4667-4677 | UMLS/C0750490 | denotes | ated antig |
| T2447 | 4190-4195 | UMLS/C2347634 | denotes | of c |
| T2446 | 3683-3695 | UMLS/C0750502 | denotes | ficance of t |
| T2445 | 4242-4249 | UMLS/C0391871 | denotes | se of p |
| T2444 | 4856-4864 | UMLS/C0079189 | denotes | ne respo |
| T2443 | 4273-4282 | UMLS/C0079189 | denotes | ines such |
| T2442 | 3312-3321 | UMLS/C0079189 | denotes | ytokines |
| T2441 | 2764-2772 | UMLS/C0079189 | denotes | ytokine |
| T2440 | 2750-2759 | UMLS/C0079189 | denotes | ytokines |
| T2439 | 2478-2486 | UMLS/C0079189 | denotes | ytokine |
| T2438 | 2351-2360 | UMLS/C0079189 | denotes | ytokines, |
| T2437 | 1434-1443 | UMLS/C0127400 | denotes | mediators |
| T2436 | 1189-1197 | UMLS/C0127400 | denotes | mediated |
| T2435 | 2116-2125 | UMLS/C0079189 | denotes | cytokines |
| T2434 | 1982-1991 | UMLS/C0079189 | denotes | cytokines |
| T2433 | 143-152 | UMLS/C0079189 | denotes | cytokines |
| T2432 | 28-36 | UMLS/C0079189 | denotes | cytokine |
| T2431 | 2374-2388 | UP/Q9JFH4 | denotes | rowth factors, |
| T2430 | 3732-3741 | UMLS/C1521721 | denotes | rted by t |
| T2617 | 4119-4130 | UMLS/C1546706 | denotes | phages and |
| T2616 | 3259-3270 | UMLS/C1546706 | denotes | acrophages |
| T2615 | 2959-2969 | UMLS/C1546706 | denotes | acrophage |
| T2614 | 2854-2865 | UMLS/C1546706 | denotes | acrophages |
| T2613 | 2036-2047 | UMLS/C1546706 | denotes | macrophages |
| T2612 | 1876-1887 | UMLS/C1546706 | denotes | macrophages |
| T2611 | 1128-1139 | UMLS/C1546706 | denotes | macrophages |
| T2610 | 1863-1874 | UMLS/C1546705 | denotes | lymphocytes |
| T2609 | 2310-2320 | UMLS/C1524073 | denotes | omponents, |
| T2608 | 318-327 | UMLS/C1524073 | denotes | component |
| T2607 | 266-275 | UMLS/C1524073 | denotes | component |
| T2606 | 751-755 | UMLS/C0376315 | denotes | form |
| T2605 | 3442-3457 | UMLS/C0011306 | denotes | ndritic cells d |
| T2604 | 1893-1908 | UMLS/C0011306 | denotes | dendritic cells |
pmc-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4779 | 5154-5162 | NN | denotes | presence |
| T4778 | 5150-5153 | DT | denotes | the |
| T4777 | 5147-5149 | IN | denotes | in |
| T4776 | 5133-5146 | NN | denotes | costimulation |
| T4775 | 5128-5132 | NN | denotes | CD28 |
| T4774 | 5124-5127 | CC | denotes | and |
| T4773 | 5120-5123 | NN | denotes | CD3 |
| T4772 | 5114-5119 | IN | denotes | after |
| T4771 | 5108-5113 | NN | denotes | IFN-γ |
| T4770 | 5105-5107 | IN | denotes | of |
| T4769 | 5094-5104 | NN | denotes | production |
| T4768 | 5090-5093 | DT | denotes | the |
| T4767 | 5077-5089 | VB | denotes | investigated |
| T4766 | 5074-5076 | PRP | denotes | we |
| T4765 | 5072-5073 | -COMMA- | denotes | , |
| T4764 | 5070-5072 | NN | denotes | RA |
| T4763 | 5067-5069 | IN | denotes | in |
| T4762 | 5056-5066 | NN | denotes | inhibition |
| T4761 | 5049-5055 | JJ | denotes | direct |
| T4760 | 5044-5048 | DT | denotes | this |
| T4759 | 5041-5043 | TO | denotes | to |
| T4758 | 5035-5040 | NN | denotes | cells |
| T4757 | 5033-5034 | NN | denotes | T |
| T4756 | 5028-5032 | JJ | denotes | CD4+ |
| T4755 | 5025-5027 | IN | denotes | of |
| T4754 | 5014-5024 | NN | denotes | resistance |
| T4753 | 5010-5013 | DT | denotes | the |
| T4752 | 5000-5009 | VB | denotes | elucidate |
| T4751 | 4997-4999 | TO | denotes | To |
| T4750 | 4990-4995 | NN | denotes | cells |
| T4749 | 4971-4989 | JJ | denotes | antigen-presenting |
| T4748 | 4968-4970 | IN | denotes | of |
| T4747 | 4959-4967 | NN | denotes | function |
| T4746 | 4955-4958 | DT | denotes | the |
| T4745 | 4940-4954 | VB | denotes | downregulating |
| T4744 | 4937-4939 | IN | denotes | by |
| T4743 | 4926-4936 | RB | denotes | indirectly |
| T4742 | 4923-4925 | IN | denotes | as |
| T4741 | 4918-4922 | RB | denotes | well |
| T4740 | 4915-4917 | RB | denotes | as |
| T4739 | 4913-4914 | -COMMA- | denotes | , |
| T4738 | 4912-4913 | -RRB- | denotes | ] |
| T4737 | 4910-4912 | CD | denotes | 24 |
| T4736 | 4909-4910 | -LRB- | denotes | [ |
| T4735 | 4901-4908 | NN | denotes | pathway |
| T4734 | 4891-4900 | NN | denotes | signaling |
| T4733 | 4886-4890 | NN | denotes | CD28 |
| T4732 | 4882-4885 | DT | denotes | the |
| T4731 | 4871-4881 | VB | denotes | inhibiting |
| T4730 | 4868-4870 | IN | denotes | by |
| T4729 | 4859-4867 | NN | denotes | response |
| T4728 | 4850-4858 | NN | denotes | cytokine |
| T4727 | 4843-4849 | NN | denotes | T-cell |
| T4726 | 4826-4842 | JJ | denotes | antigen-specific |
| T4725 | 4822-4825 | DT | denotes | the |
| T4724 | 4815-4821 | VB | denotes | blocks |
| T4723 | 4803-4814 | RB | denotes | efficiently |
| T4722 | 4797-4802 | NN | denotes | IL-10 |
| T4721 | 4794-4795 | -RRB- | denotes | ] |
| T4720 | 4792-4794 | CD | denotes | 23 |
| T4719 | 4791-4792 | -LRB- | denotes | [ |
| T4718 | 4783-4790 | NN | denotes | avidity |
| T4717 | 4778-4782 | JJ | denotes | high |
| T4716 | 4773-4777 | IN | denotes | with |
| T4715 | 4768-4772 | NN | denotes | CD86 |
| T4714 | 4764-4767 | CC | denotes | and |
| T4713 | 4759-4763 | NN | denotes | CD80 |
| T4712 | 4756-4758 | TO | denotes | to |
| T4711 | 4748-4755 | VB | denotes | binding |
| T4710 | 4745-4747 | IN | denotes | by |
| T4709 | 4739-4744 | NN | denotes | cells |
| T4708 | 4737-4738 | NN | denotes | T |
| T4707 | 4734-4736 | IN | denotes | on |
| T4706 | 4729-4733 | NN | denotes | CD28 |
| T4705 | 4726-4728 | IN | denotes | of |
| T4704 | 4715-4725 | NN | denotes | engagement |
| T4703 | 4711-4714 | DT | denotes | the |
| T4702 | 4705-4710 | VB | denotes | block |
| T4701 | 4701-4704 | MD | denotes | can |
| T4700 | 4695-4700 | WDT | denotes | which |
| T4699 | 4693-4694 | -COMMA- | denotes | , |
| T4698 | 4689-4693 | NN | denotes | -IgG |
| T4697 | 4688-4689 | -RRB- | denotes | ) |
| T4696 | 4683-4688 | NN | denotes | CD152 |
| T4695 | 4682-4683 | -LRB- | denotes | ( |
| T4694 | 4680-4681 | CD | denotes | 4 |
| T4693 | 4672-4679 | NN | denotes | antigen |
| T4692 | 4654-4671 | JJ | denotes | T-cell-associated |
| T4691 | 4644-4653 | JJ | denotes | cytotoxic |
| T4690 | 4641-4643 | IN | denotes | of |
| T4689 | 4633-4640 | NN | denotes | protein |
| T4688 | 4626-4632 | NN | denotes | fusion |
| T4687 | 4621-4625 | IN | denotes | with |
| T4686 | 4610-4620 | NN | denotes | activation |
| T4685 | 4603-4609 | NN | denotes | T-cell |
| T4684 | 4600-4602 | IN | denotes | of |
| T4683 | 4589-4599 | NN | denotes | inhibition |
| T4682 | 4579-4588 | JJ | denotes | selective |
| T4681 | 4576-4578 | IN | denotes | by |
| T4680 | 4568-4575 | NN | denotes | disease |
| T4679 | 4561-4567 | JJ | denotes | active |
| T4678 | 4558-4560 | IN | denotes | of |
| T4677 | 4548-4557 | NN | denotes | treatment |
| T4676 | 4537-4547 | JJ | denotes | successful |
| T4675 | 4534-4536 | IN | denotes | by |
| T4674 | 4527-4533 | VB | denotes | proved |
| T4673 | 4518-4526 | RB | denotes | recently |
| T4672 | 4514-4517 | VB | denotes | was |
| T4671 | 4504-4513 | NN | denotes | synovitis |
| T4670 | 4501-4503 | NN | denotes | RA |
| T4669 | 4498-4500 | IN | denotes | in |
| T4668 | 4493-4497 | NN | denotes | role |
| T4667 | 4482-4492 | JJ | denotes | obligatory |
| T4666 | 4476-4481 | PRP-DOLLAR- | denotes | Their |
| T4665 | 4463-4474 | NN | denotes | destruction |
| T4664 | 4458-4462 | NN | denotes | bone |
| T4663 | 4438-4457 | JJ | denotes | osteoclast-mediated |
| T4662 | 4434-4437 | CC | denotes | and |
| T4661 | 4427-4433 | NN | denotes | factor |
| T4660 | 4416-4426 | JJ | denotes | rheumatoid |
| T4659 | 4413-4415 | IN | denotes | as |
| T4658 | 4408-4412 | JJ | denotes | such |
| T4657 | 4393-4407 | NN | denotes | autoantibodies |
| T4656 | 4390-4392 | IN | denotes | of |
| T4655 | 4379-4389 | NN | denotes | production |
| T4654 | 4372-4378 | NN | denotes | B-cell |
| T4653 | 4362-4371 | VB | denotes | stimulate |
| T4652 | 4356-4361 | MD | denotes | could |
| T4651 | 4350-4355 | NN | denotes | cells |
| T4650 | 4348-4349 | NN | denotes | T |
| T4649 | 4343-4347 | JJ | denotes | CD4+ |
| T4648 | 4341-4342 | -COMMA- | denotes | , |
| T4647 | 4333-4341 | NN | denotes | addition |
| T4646 | 4330-4332 | IN | denotes | In |
| T4645 | 4327-4328 | -RRB- | denotes | ] |
| T4644 | 4322-4327 | CD | denotes | 21,22 |
| T4643 | 4321-4322 | -LRB- | denotes | [ |
| T4642 | 4315-4320 | NN | denotes | IL-17 |
| T4641 | 4311-4314 | CC | denotes | and |
| T4640 | 4308-4310 | NN | denotes | -γ |
| T4639 | 4307-4308 | -RRB- | denotes | ) |
| T4638 | 4304-4307 | NN | denotes | IFN |
| T4637 | 4303-4304 | -LRB- | denotes | ( |
| T4636 | 4297-4302 | NN | denotes | gamma |
| T4635 | 4286-4296 | NN | denotes | interferon |
| T4634 | 4283-4285 | IN | denotes | as |
| T4633 | 4278-4282 | JJ | denotes | such |
| T4632 | 4268-4277 | NN | denotes | cytokines |
| T4631 | 4264-4267 | NN | denotes | Th1 |
| T4630 | 4248-4263 | JJ | denotes | proinflammatory |
| T4629 | 4245-4247 | IN | denotes | of |
| T4628 | 4237-4244 | NN | denotes | release |
| T4627 | 4233-4236 | DT | denotes | the |
| T4626 | 4230-4232 | IN | denotes | as |
| T4625 | 4225-4229 | RB | denotes | well |
| T4624 | 4222-4224 | RB | denotes | as |
| T4623 | 4220-4221 | -COMMA- | denotes | , |
| T4622 | 4216-4220 | NN | denotes | CD11 |
| T4621 | 4212-4215 | CC | denotes | and |
| T4620 | 4207-4211 | NN | denotes | CD69 |
| T4619 | 4199-4206 | NN | denotes | surface |
| T4618 | 4194-4198 | NN | denotes | cell |
| T4617 | 4191-4193 | IN | denotes | of |
| T4616 | 4185-4190 | NN | denotes | means |
| T4615 | 4182-4184 | IN | denotes | by |
| T4614 | 4172-4181 | NN | denotes | signaling |
| T4613 | 4164-4171 | NN | denotes | surface |
| T4612 | 4159-4163 | NN | denotes | cell |
| T4611 | 4151-4158 | IN | denotes | through |
| T4610 | 4139-4150 | NN | denotes | fibroblasts |
| T4609 | 4130-4138 | JJ | denotes | synovial |
| T4608 | 4126-4129 | CC | denotes | and |
| T4607 | 4114-4125 | NN | denotes | macrophages |
| T4606 | 4111-4113 | IN | denotes | of |
| T4605 | 4100-4110 | NN | denotes | activation |
| T4604 | 4096-4099 | DT | denotes | the |
| T4603 | 4085-4095 | VB | denotes | sustaining |
| T4602 | 4082-4084 | IN | denotes | in |
| T4601 | 4074-4081 | JJ | denotes | crucial |
| T4600 | 4071-4073 | VB | denotes | be |
| T4599 | 4067-4070 | MD | denotes | may |
| T4598 | 4065-4066 | -COMMA- | denotes | , |
| T4597 | 4059-4065 | NN | denotes | number |
| T4596 | 4056-4058 | IN | denotes | in |
| T4595 | 4052-4055 | JJ | denotes | few |
| T4594 | 4045-4051 | IN | denotes | though |
| T4593 | 4040-4044 | RB | denotes | even |
| T4592 | 4038-4039 | -COMMA- | denotes | , |
| T4591 | 4033-4038 | NN | denotes | cells |
| T4590 | 4031-4032 | NN | denotes | T |
| T4589 | 4026-4030 | JJ | denotes | CD4+ |
| T4588 | 4016-4025 | VB | denotes | activated |
| T4587 | 4013-4015 | IN | denotes | of |
| T4586 | 4003-4012 | NN | denotes | emergence |
| T4585 | 3992-4002 | VB | denotes | continuing |
| T4584 | 3988-3991 | DT | denotes | The |
| T4583 | 3985-3986 | -RRB- | denotes | ] |
| T4582 | 3980-3985 | CD | denotes | 18-20 |
| T4581 | 3979-3980 | -LRB- | denotes | [ |
| T4580 | 3976-3978 | NN | denotes | ST |
| T4579 | 3967-3975 | JJ | denotes | inflamed |
| T4578 | 3963-3966 | DT | denotes | the |
| T4577 | 3960-3962 | IN | denotes | in |
| T4576 | 3958-3959 | -COMMA- | denotes | , |
| T4575 | 3954-3958 | NN | denotes | CD86 |
| T4574 | 3950-3953 | CC | denotes | and |
| T4573 | 3945-3949 | NN | denotes | CD80 |
| T4572 | 3943-3944 | -COMMA- | denotes | , |
| T4571 | 3936-3943 | NN | denotes | ligands |
| T4570 | 3931-3935 | NN | denotes | CD28 |
| T4569 | 3926-3930 | DT | denotes | both |
| T4568 | 3922-3925 | CC | denotes | and |
| T4567 | 3912-3921 | NN | denotes | molecules |
| T4566 | 3909-3911 | CD | denotes | II |
| T4565 | 3903-3908 | NN | denotes | class |
| T4564 | 3899-3902 | NN | denotes | MHC |
| T4494 | 3460-3462 | TO | denotes | to |
| T4493 | 3456-3459 | JJ | denotes | due |
| T4492 | 3450-3455 | NN | denotes | cells |
| T4491 | 3440-3449 | JJ | denotes | dendritic |
| T4490 | 3434-3439 | NN | denotes | fluid |
| T4489 | 3425-3433 | JJ | denotes | synovial |
| T4488 | 3422-3424 | IN | denotes | in |
| T4487 | 3412-3421 | VB | denotes | decreased |
| T4486 | 3409-3411 | VB | denotes | is |
| T4485 | 3401-3408 | NN | denotes | IL-10R1 |
| T4484 | 3398-3400 | IN | denotes | of |
| T4483 | 3387-3397 | NN | denotes | expression |
| T4482 | 3379-3386 | NN | denotes | surface |
| T4481 | 3374-3378 | NN | denotes | Cell |
| T4480 | 3371-3372 | -RRB- | denotes | ] |
| T4479 | 3366-3371 | CD | denotes | 13,14 |
| T4478 | 3365-3366 | -LRB- | denotes | [ |
| T4477 | 3355-3364 | NN | denotes | complexes |
| T4476 | 3348-3354 | JJ | denotes | immune |
| T4475 | 3344-3347 | CC | denotes | and |
| T4474 | 3339-3343 | NN | denotes | IL-1 |
| T4473 | 3335-3338 | CC | denotes | and |
| T4472 | 3329-3334 | NN | denotes | TNF-α |
| T4471 | 3326-3328 | IN | denotes | as |
| T4470 | 3321-3325 | JJ | denotes | such |
| T4469 | 3311-3320 | NN | denotes | cytokines |
| T4468 | 3295-3310 | JJ | denotes | proinflammatory |
| T4467 | 3292-3294 | TO | denotes | to |
| T4466 | 3283-3291 | NN | denotes | exposure |
| T4465 | 3275-3282 | JJ | denotes | chronic |
| T4464 | 3270-3274 | IN | denotes | upon |
| T4463 | 3258-3269 | NN | denotes | macrophages |
| T4462 | 3255-3257 | IN | denotes | in |
| T4461 | 3246-3254 | VB | denotes | impaired |
| T4460 | 3243-3245 | VB | denotes | is |
| T4459 | 3233-3242 | NN | denotes | signaling |
| T4458 | 3227-3232 | NN | denotes | IL-10 |
| T4457 | 3213-3225 | NN | denotes | inflammation |
| T4456 | 3205-3212 | JJ | denotes | chronic |
| T4455 | 3198-3204 | IN | denotes | during |
| T4454 | 3185-3197 | NN | denotes | transduction |
| T4453 | 3178-3184 | NN | denotes | signal |
| T4452 | 3175-3177 | IN | denotes | of |
| T4451 | 3169-3174 | NN | denotes | level |
| T4450 | 3165-3168 | DT | denotes | the |
| T4449 | 3162-3164 | IN | denotes | at |
| T4448 | 3152-3161 | VB | denotes | modulated |
| T4447 | 3149-3151 | VB | denotes | be |
| T4446 | 3146-3148 | TO | denotes | to |
| T4445 | 3138-3145 | VB | denotes | appears |
| T4444 | 3132-3137 | NN | denotes | IL-10 |
| T4443 | 3129-3131 | IN | denotes | of |
| T4442 | 3122-3128 | NN | denotes | action |
| T4441 | 3104-3121 | JJ | denotes | anti-inflammatory |
| T4440 | 3100-3103 | DT | denotes | the |
| T4439 | 3098-3099 | -COMMA- | denotes | , |
| T4438 | 3090-3098 | NN | denotes | addition |
| T4437 | 3087-3089 | IN | denotes | In |
| T4436 | 3084-3085 | -RRB- | denotes | ] |
| T4435 | 3082-3084 | CD | denotes | 12 |
| T4434 | 3081-3082 | -LRB- | denotes | [ |
| T4433 | 3074-3080 | NN | denotes | events |
| T4432 | 3058-3073 | JJ | denotes | proinflammatory |
| T4431 | 3055-3057 | IN | denotes | of |
| T4430 | 3047-3054 | NN | denotes | cascade |
| T4429 | 3043-3046 | DT | denotes | the |
| T4428 | 3028-3042 | VB | denotes | counterbalance |
| T4427 | 3025-3027 | TO | denotes | to |
| T4426 | 3012-3024 | JJ | denotes | insufficient |
| T4425 | 3009-3011 | VB | denotes | is |
| T4424 | 3003-3008 | NN | denotes | level |
| T4423 | 2992-3002 | NN | denotes | expression |
| T4422 | 2988-2991 | DT | denotes | the |
| T4421 | 2984-2987 | CC | denotes | but |
| T4420 | 2982-2983 | -COMMA- | denotes | , |
| T4419 | 2977-2982 | NN | denotes | cells |
| T4418 | 2973-2976 | NN | denotes | Th1 |
| T4417 | 2969-2972 | CC | denotes | and |
| T4416 | 2958-2968 | NN | denotes | macrophage |
| T4415 | 2954-2957 | IN | denotes | for |
| T4414 | 2944-2953 | NN | denotes | regulator |
| T4413 | 2935-2943 | JJ | denotes | negative |
| T4412 | 2933-2934 | DT | denotes | a |
| T4411 | 2930-2932 | IN | denotes | as |
| T4410 | 2924-2929 | VB | denotes | known |
| T4409 | 2919-2923 | RB | denotes | best |
| T4408 | 2916-2918 | VB | denotes | is |
| T4407 | 2914-2915 | -COMMA- | denotes | , |
| T4406 | 2913-2914 | -RRB- | denotes | ) |
| T4405 | 2911-2913 | NN | denotes | ST |
| T4404 | 2910-2911 | -LRB- | denotes | ( |
| T4403 | 2903-2909 | NN | denotes | tissue |
| T4402 | 2894-2902 | JJ | denotes | synovial |
| T4401 | 2890-2893 | DT | denotes | the |
| T4400 | 2887-2889 | IN | denotes | in |
| T4399 | 2881-2886 | NN | denotes | cells |
| T4398 | 2879-2880 | NN | denotes | T |
| T4397 | 2876-2878 | IN | denotes | by |
| T4396 | 2869-2875 | RB | denotes | partly |
| T4395 | 2865-2868 | CC | denotes | and |
| T4394 | 2853-2864 | NN | denotes | macrophages |
| T4393 | 2850-2852 | IN | denotes | by |
| T4392 | 2841-2849 | VB | denotes | produced |
| T4391 | 2839-2840 | -COMMA- | denotes | , |
| T4390 | 2834-2839 | NN | denotes | IL-10 |
| T4389 | 2826-2832 | NN | denotes | joints |
| T4388 | 2823-2825 | NN | denotes | RA |
| T4387 | 2820-2822 | IN | denotes | in |
| T4386 | 2809-2819 | NN | denotes | quantities |
| T4385 | 2803-2808 | JJ | denotes | large |
| T4384 | 2800-2802 | IN | denotes | in |
| T4383 | 2792-2799 | JJ | denotes | present |
| T4382 | 2787-2791 | RB | denotes | also |
| T4381 | 2783-2786 | VB | denotes | are |
| T4380 | 2772-2782 | NN | denotes | inhibitors |
| T4379 | 2763-2771 | NN | denotes | cytokine |
| T4378 | 2759-2762 | CC | denotes | and |
| T4377 | 2749-2758 | NN | denotes | cytokines |
| T4376 | 2731-2748 | JJ | denotes | anti-inflammatory |
| T4375 | 2729-2730 | -COMMA- | denotes | , |
| T4374 | 2722-2729 | RB | denotes | However |
| T4373 | 2719-2720 | -RRB- | denotes | ] |
| T4372 | 2717-2719 | CD | denotes | 11 |
| T4371 | 2716-2717 | -LRB- | denotes | [ |
| T4370 | 2700-2715 | NN | denotes | differentiation |
| T4369 | 2695-2699 | NN | denotes | cell |
| T4368 | 2685-2694 | NN | denotes | precursor |
| T4367 | 2671-2684 | JJ | denotes | hematopoietic |
| T4366 | 2667-2670 | CC | denotes | and |
| T4365 | 2665-2666 | -COMMA- | denotes | , |
| T4364 | 2656-2665 | NN | denotes | functions |
| T4363 | 2649-2655 | NN | denotes | T-cell |
| T4362 | 2647-2648 | -COMMA- | denotes | , |
| T4361 | 2642-2647 | NN | denotes | cells |
| T4360 | 2635-2641 | NN | denotes | plasma |
| T4359 | 2630-2634 | IN | denotes | into |
| T4358 | 2619-2629 | NN | denotes | maturation |
| T4357 | 2612-2618 | NN | denotes | B-cell |
| T4356 | 2610-2611 | -COMMA- | denotes | , |
| T4355 | 2602-2610 | NN | denotes | response |
| T4354 | 2590-2601 | NN | denotes | acute-phase |
| T4353 | 2586-2589 | DT | denotes | the |
| T4352 | 2575-2585 | VB | denotes | simulating |
| T4351 | 2567-2574 | VB | denotes | include |
| T4350 | 2559-2566 | NN | denotes | actions |
| T4349 | 2543-2558 | JJ | denotes | proinflammatory |
| T4348 | 2539-2542 | PRP-DOLLAR- | denotes | its |
| T4347 | 2535-2538 | CC | denotes | and |
| T4346 | 2533-2534 | -COMMA- | denotes | , |
| T4345 | 2522-2533 | NN | denotes | fibroblasts |
| T4344 | 2512-2521 | VB | denotes | activated |
| T4343 | 2509-2511 | IN | denotes | by |
| T4342 | 2495-2508 | RB | denotes | substantially |
| T4341 | 2486-2494 | VB | denotes | produced |
| T4340 | 2477-2485 | NN | denotes | cytokine |
| T4339 | 2465-2476 | JJ | denotes | pleiotropic |
| T4338 | 2463-2464 | DT | denotes | a |
| T4337 | 2460-2462 | VB | denotes | is |
| T4336 | 2455-2459 | NN | denotes | IL-6 |
| T4335 | 2452-2453 | -RRB- | denotes | ] |
| T4334 | 2450-2452 | CD | denotes | 10 |
| T4333 | 2449-2450 | -LRB- | denotes | [ |
| T4332 | 2441-2448 | NN | denotes | species |
| T4331 | 2434-2440 | NN | denotes | oxygen |
| T4330 | 2425-2433 | JJ | denotes | reactive |
| T4329 | 2421-2424 | CC | denotes | and |
| T4328 | 2419-2420 | -COMMA- | denotes | , |
| T4327 | 2414-2419 | NN | denotes | oxide |
| T4326 | 2407-2413 | JJ | denotes | nitric |
| T4325 | 2405-2406 | -COMMA- | denotes | , |
| T4324 | 2396-2405 | NN | denotes | proteases |
| T4323 | 2389-2395 | NN | denotes | matrix |
| T4322 | 2387-2388 | -COMMA- | denotes | , |
| T4321 | 2380-2387 | NN | denotes | factors |
| T4320 | 2373-2379 | NN | denotes | growth |
| T4319 | 2371-2372 | -COMMA- | denotes | , |
| T4318 | 2361-2371 | NN | denotes | chemokines |
| T4317 | 2359-2360 | -COMMA- | denotes | , |
| T4316 | 2350-2359 | NN | denotes | cytokines |
| T4315 | 2337-2349 | JJ | denotes | inflammatory |
| T4314 | 2331-2336 | JJ | denotes | other |
| T4313 | 2321-2330 | VB | denotes | including |
| T4312 | 2319-2320 | -COMMA- | denotes | , |
| T4311 | 2309-2319 | NN | denotes | components |
| T4812 | 5321-5329 | NN | denotes | patients |
| T4811 | 5318-5320 | NN | denotes | RA |
| T4810 | 5313-5317 | IN | denotes | from |
| T4809 | 5307-5312 | NN | denotes | cells |
| T4808 | 5305-5306 | NN | denotes | T |
| T4807 | 5300-5304 | JJ | denotes | CD4+ |
| T4806 | 5298-5299 | -RRB- | denotes | ) |
| T4805 | 5296-5298 | NN | denotes | PB |
| T4804 | 5295-5296 | -LRB- | denotes | ( |
| T4803 | 5289-5294 | NN | denotes | blood |
| T4802 | 5278-5288 | JJ | denotes | peripheral |
| T4801 | 5275-5277 | IN | denotes | in |
| T4800 | 5270-5274 | NN | denotes | mRNA |
| T4799 | 5264-5269 | NN | denotes | SOCS3 |
| T4798 | 5260-5263 | CC | denotes | and |
| T4797 | 5254-5259 | NN | denotes | SOCS1 |
| T4796 | 5251-5253 | IN | denotes | of |
| T4795 | 5240-5250 | NN | denotes | expression |
| T4794 | 5236-5239 | DT | denotes | the |
| T4793 | 5232-5235 | CC | denotes | and |
| T4792 | 5230-5231 | -COMMA- | denotes | , |
| T4791 | 5225-5230 | NN | denotes | IL-10 |
| T4790 | 5222-5224 | IN | denotes | by |
| T4789 | 5206-5221 | NN | denotes | phosphorylation |
| T4788 | 5200-5205 | NN | denotes | STAT3 |
| T4787 | 5196-5199 | CC | denotes | and |
| T4786 | 5190-5195 | NN | denotes | STAT1 |
| T4785 | 5187-5189 | IN | denotes | of |
| T4784 | 5177-5186 | NN | denotes | induction |
| T4783 | 5173-5176 | DT | denotes | the |
| T4782 | 5171-5172 | -COMMA- | denotes | , |
| T4781 | 5166-5171 | NN | denotes | IL-10 |
| T4780 | 5163-5165 | IN | denotes | of |
| T4310 | 2300-2308 | NN | denotes | effector |
| T4309 | 2297-2299 | TO | denotes | to |
| T4308 | 2292-2296 | NN | denotes | rise |
| T4307 | 2287-2291 | VB | denotes | give |
| T4306 | 2282-2286 | PRP | denotes | they |
| T4305 | 2278-2281 | CC | denotes | and |
| T4304 | 2276-2277 | -COMMA- | denotes | , |
| T4303 | 2265-2276 | NN | denotes | destruction |
| T4302 | 2259-2264 | JJ | denotes | joint |
| T4301 | 2255-2258 | CC | denotes | and |
| T4300 | 2242-2254 | NN | denotes | inflammation |
| T4299 | 2234-2241 | JJ | denotes | chronic |
| T4298 | 2231-2233 | IN | denotes | of |
| T4297 | 2223-2230 | NN | denotes | process |
| T4296 | 2219-2222 | DT | denotes | the |
| T4295 | 2216-2218 | IN | denotes | in |
| T4294 | 2208-2215 | JJ | denotes | crucial |
| T4293 | 2204-2207 | VB | denotes | are |
| T4292 | 2202-2203 | -COMMA- | denotes | , |
| T4291 | 2194-2202 | NN | denotes | products |
| T4290 | 2183-2193 | NN | denotes | macrophage |
| T4289 | 2177-2182 | JJ | denotes | major |
| T4288 | 2173-2176 | CD | denotes | two |
| T4287 | 2171-2172 | -COMMA- | denotes | , |
| T4286 | 2167-2171 | NN | denotes | IL-1 |
| T4285 | 2163-2166 | CC | denotes | and |
| T4284 | 2161-2162 | -RRB- | denotes | ) |
| T4283 | 2156-2161 | NN | denotes | TNF-α |
| T4282 | 2155-2156 | -LRB- | denotes | ( |
| T4281 | 2149-2154 | NN | denotes | alpha |
| T4280 | 2142-2148 | NN | denotes | factor |
| T4279 | 2133-2141 | NN | denotes | necrosis |
| T4269 | 2052-2060 | JJ | denotes | synovial |
| T4268 | 2048-2051 | CC | denotes | and |
| T4267 | 2036-2047 | NN | denotes | macrophages |
| T4266 | 2032-2035 | CC | denotes | and |
| T4265 | 2030-2031 | -COMMA- | denotes | , |
| T4264 | 2025-2030 | NN | denotes | joint |
| T4263 | 2016-2024 | JJ | denotes | inflamed |
| T4262 | 2012-2015 | DT | denotes | the |
| T4261 | 2009-2011 | IN | denotes | in |
| T4260 | 1996-2008 | VB | denotes | overproduced |
| T4259 | 1992-1995 | VB | denotes | are |
| T4258 | 1982-1991 | NN | denotes | cytokines |
| T4257 | 1973-1981 | JJ | denotes | Numerous |
| T4256 | 1966-1971 | NN | denotes | cells |
| T4255 | 1950-1965 | JJ | denotes | fibroblast-like |
| T4254 | 1941-1949 | JJ | denotes | synovial |
| T4253 | 1938-1940 | IN | denotes | of |
| T4252 | 1924-1937 | NN | denotes | proliferation |
| T4251 | 1919-1923 | IN | denotes | with |
| T4250 | 1910-1918 | RB | denotes | together |
| T4249 | 1908-1909 | -COMMA- | denotes | , |
| T4248 | 1903-1908 | NN | denotes | cells |
| T4247 | 1893-1902 | JJ | denotes | dendritic |
| T4246 | 1889-1892 | CC | denotes | and |
| T4245 | 1887-1888 | -COMMA- | denotes | , |
| T4244 | 1876-1887 | NN | denotes | macrophages |
| T4243 | 1874-1875 | -COMMA- | denotes | , |
| T4242 | 1863-1874 | NN | denotes | lymphocytes |
| T4241 | 1860-1862 | IN | denotes | as |
| T4240 | 1855-1859 | JJ | denotes | such |
| T4239 | 1853-1854 | -COMMA- | denotes | , |
| T4238 | 1848-1853 | NN | denotes | cells |
| T4237 | 1835-1847 | JJ | denotes | inflammatory |
| T4236 | 1832-1834 | IN | denotes | of |
| T4235 | 1824-1831 | NN | denotes | variety |
| T4234 | 1822-1823 | DT | denotes | a |
| T4233 | 1819-1821 | IN | denotes | of |
| T4232 | 1808-1818 | NN | denotes | infiltrate |
| T4231 | 1805-1807 | DT | denotes | an |
| T4230 | 1802-1804 | IN | denotes | by |
| T4229 | 1788-1801 | VB | denotes | characterized |
| T4228 | 1785-1787 | VB | denotes | is |
| T4227 | 1783-1784 | -RRB- | denotes | ) |
| T4226 | 1781-1783 | NN | denotes | RA |
| T4225 | 1780-1781 | -LRB- | denotes | ( |
| T4224 | 1770-1779 | NN | denotes | arthritis |
| T4223 | 1759-1769 | JJ | denotes | rheumatoid |
| T4222 | 1756-1758 | IN | denotes | of |
| T4221 | 1747-1755 | NN | denotes | membrane |
| T4220 | 1738-1746 | JJ | denotes | synovial |
| T4219 | 1734-1737 | DT | denotes | The |
| T4218 | 1731-1732 | -RRB- | denotes | ] |
| T4217 | 1728-1731 | CD | denotes | 8,9 |
| T4216 | 1727-1728 | -LRB- | denotes | [ |
| T4215 | 1721-1726 | NN | denotes | IL-10 |
| T4214 | 1718-1720 | IN | denotes | by |
| T4213 | 1710-1717 | VB | denotes | induced |
| T4212 | 1705-1709 | DT | denotes | that |
| T4211 | 1701-1704 | RB | denotes | not |
| T4210 | 1697-1700 | CC | denotes | but |
| T4209 | 1692-1696 | NN | denotes | IL-6 |
| T4208 | 1689-1691 | IN | denotes | by |
| T4207 | 1681-1688 | VB | denotes | induced |
| T4206 | 1670-1680 | NN | denotes | activation |
| T4205 | 1664-1669 | NN | denotes | STAT3 |
| T4204 | 1655-1663 | VB | denotes | blocking |
| T4203 | 1642-1654 | RB | denotes | specifically |
| T4202 | 1639-1641 | IN | denotes | by |
| T4201 | 1637-1638 | -COMMA- | denotes | , |
| T4200 | 1633-1637 | NN | denotes | IL-6 |
| T4199 | 1629-1632 | CC | denotes | and |
| T4198 | 1623-1628 | NN | denotes | IL-10 |
| T4197 | 1620-1622 | IN | denotes | of |
| T4196 | 1613-1619 | NN | denotes | action |
| T4195 | 1603-1612 | JJ | denotes | divergent |
| T4194 | 1599-1602 | DT | denotes | the |
| T4193 | 1588-1598 | VB | denotes | regulating |
| T4192 | 1585-1587 | IN | denotes | in |
| T4191 | 1580-1584 | NN | denotes | role |
| T4190 | 1576-1579 | JJ | denotes | key |
| T4189 | 1574-1575 | DT | denotes | a |
| T4188 | 1568-1573 | VB | denotes | plays |
| T4187 | 1562-1567 | NN | denotes | SOCS3 |
| T4186 | 1557-1561 | IN | denotes | that |
| T4185 | 1548-1556 | VB | denotes | indicate |
| T4184 | 1540-1547 | NN | denotes | studies |
| T4183 | 1533-1539 | JJ | denotes | Recent |
| T4182 | 1530-1531 | -RRB- | denotes | ] |
| T4181 | 1529-1530 | CD | denotes | 7 |
| T4180 | 1528-1529 | -LRB- | denotes | [ |
| T4179 | 1518-1527 | VB | denotes | clarified |
| T4178 | 1513-1517 | VB | denotes | been |
| T4177 | 1508-1512 | VB | denotes | have |
| T4176 | 1499-1507 | NN | denotes | pathways |
| T4175 | 1489-1498 | NN | denotes | signaling |
| T4174 | 1480-1488 | NN | denotes | cytokine |
| T4173 | 1471-1479 | VB | denotes | opposing |
| T4172 | 1468-1470 | IN | denotes | by |
| T4171 | 1457-1467 | NN | denotes | inhibition |
| T4170 | 1447-1456 | NN | denotes | crosstalk |
| T4169 | 1444-1446 | IN | denotes | of |
| T4168 | 1434-1443 | NN | denotes | mediators |
| T4167 | 1430-1433 | DT | denotes | the |
| T4166 | 1427-1429 | IN | denotes | as |
| T4165 | 1421-1426 | NN | denotes | roles |
| T4164 | 1415-1420 | PRP-DOLLAR- | denotes | their |
| T4163 | 1411-1414 | CC | denotes | but |
| T4162 | 1409-1410 | -COMMA- | denotes | , |
| T4161 | 1404-1409 | VB | denotes | loops |
| T4160 | 1393-1403 | NN | denotes | inhibition |
| T4159 | 1384-1392 | NN | denotes | feedback |
| T4158 | 1376-1383 | JJ | denotes | classic |
| T4157 | 1373-1375 | IN | denotes | in |
| T4156 | 1369-1372 | VB | denotes | act |
| T4155 | 1365-1368 | MD | denotes | can |
| T4154 | 1360-1364 | WDT | denotes | that |
| T4153 | 1349-1359 | NN | denotes | inhibitors |
| T4152 | 1342-1348 | NN | denotes | kinase |
| T4151 | 1338-1341 | NN | denotes | JAK |
| T4150 | 1327-1337 | JJ | denotes | endogenous |
| T4149 | 1324-1326 | IN | denotes | of |
| T4148 | 1317-1323 | NN | denotes | family |
| T4147 | 1315-1316 | DT | denotes | a |
| T4146 | 1312-1314 | IN | denotes | as |
| T4145 | 1301-1311 | VB | denotes | identified |
| T4144 | 1296-1300 | VB | denotes | been |
| T4143 | 1291-1295 | VB | denotes | have |
| T4142 | 1282-1290 | NN | denotes | proteins |
| T4141 | 1280-1281 | -RRB- | denotes | ) |
| T4140 | 1276-1280 | NN | denotes | SOCS |
| T4139 | 1275-1276 | -LRB- | denotes | ( |
| T4138 | 1265-1274 | NN | denotes | signaling |
| T4137 | 1256-1264 | NN | denotes | cytokine |
| T4136 | 1253-1255 | IN | denotes | of |
| T4135 | 1242-1252 | NN | denotes | suppressor |
| T4134 | 1238-1241 | DT | denotes | The |
| T4133 | 1235-1236 | -RRB- | denotes | ] |
| T4132 | 1234-1235 | CD | denotes | 6 |
| T4131 | 1233-1234 | -LRB- | denotes | [ |
| T4130 | 1227-1232 | NN | denotes | cells |
| T4129 | 1225-1226 | NN | denotes | T |
| T4128 | 1222-1224 | IN | denotes | in |
| T4127 | 1212-1221 | NN | denotes | apoptosis |
| T4126 | 1209-1211 | IN | denotes | of |
| T4125 | 1198-1208 | NN | denotes | prevention |
| T4124 | 1184-1197 | JJ | denotes | IL-6-mediated |
| T4123 | 1180-1183 | IN | denotes | for |
| T4122 | 1168-1179 | JJ | denotes | responsible |
| T4121 | 1165-1167 | VB | denotes | is |
| T4120 | 1161-1164 | CC | denotes | but |
| T4119 | 1159-1160 | -COMMA- | denotes | , |
| T4118 | 1158-1159 | -RRB- | denotes | ] |
| T4117 | 1157-1158 | CD | denotes | 5 |
| T4116 | 1156-1157 | -LRB- | denotes | [ |
| T4115 | 1144-1155 | NN | denotes | neutrophils |
| T4114 | 1140-1143 | CC | denotes | and |
| T4113 | 1128-1139 | NN | denotes | macrophages |
| T4112 | 1125-1127 | IN | denotes | in |
| T4111 | 1115-1124 | NN | denotes | reactions |
| T4110 | 1097-1114 | JJ | denotes | anti-inflammatory |
| T4109 | 1082-1096 | JJ | denotes | IL-10-mediated |
| T4108 | 1078-1081 | IN | denotes | for |
| T4107 | 1068-1077 | JJ | denotes | essential |
| T4106 | 1065-1067 | VB | denotes | is |
| T4105 | 1054-1064 | NN | denotes | activation |
| T4104 | 1048-1053 | NN | denotes | STAT3 |
| T4103 | 1043-1047 | IN | denotes | that |
| T4102 | 1037-1042 | VB | denotes | shown |
| T4101 | 1032-1036 | VB | denotes | have |
| T4100 | 1027-1031 | NN | denotes | mice |
| T4099 | 1011-1026 | JJ | denotes | STAT3-deficient |
| T4098 | 992-1010 | JJ | denotes | cell-type-specific |
| T4097 | 989-991 | IN | denotes | of |
| T4096 | 981-988 | NN | denotes | Studies |
| T4095 | 978-979 | -RRB- | denotes | ] |
| T4094 | 977-978 | CD | denotes | 4 |
| T4093 | 976-977 | -LRB- | denotes | [ |
| T4092 | 966-975 | NN | denotes | responses |
| T4091 | 950-965 | JJ | denotes | proinflammatory |
| T4090 | 937-949 | JJ | denotes | IL-6-derived |
| T4089 | 933-936 | CC | denotes | and |
| T4088 | 915-932 | JJ | denotes | anti-inflammatory |
| T4087 | 901-914 | JJ | denotes | IL-10-derived |
| T4086 | 896-900 | DT | denotes | both |
| T4563 | 3896-3898 | IN | denotes | of |
| T4562 | 3885-3895 | NN | denotes | expression |
| T4561 | 3874-3884 | JJ | denotes | high-level |
| T4560 | 3870-3873 | DT | denotes | the |
| T4559 | 3867-3869 | IN | denotes | by |
| T4558 | 3863-3866 | CC | denotes | and |
| T4557 | 3861-3862 | -COMMA- | denotes | , |
| T4556 | 3860-3861 | -RRB- | denotes | ] |
| T4555 | 3855-3860 | CD | denotes | 16,17 |
| T4554 | 3854-3855 | -LRB- | denotes | [ |
| T4553 | 3845-3853 | NN | denotes | severity |
| T4552 | 3841-3844 | CC | denotes | and |
| T4551 | 3826-3840 | NN | denotes | susceptibility |
| T4550 | 3818-3825 | NN | denotes | disease |
| T4549 | 3813-3817 | IN | denotes | with |
| T4548 | 3799-3812 | NN | denotes | HLA-DRB1*0401 |
| T4547 | 3795-3798 | CC | denotes | and |
| T4546 | 3781-3794 | NN | denotes | HLA-DRB1*0404 |
| T4545 | 3772-3780 | NN | denotes | antigens |
| T4544 | 3769-3771 | CD | denotes | II |
| T4543 | 3763-3768 | NN | denotes | class |
| T4542 | 3759-3762 | NN | denotes | MHC |
| T4541 | 3755-3758 | DT | denotes | the |
| T4540 | 3752-3754 | IN | denotes | of |
| T4539 | 3744-3751 | NN | denotes | linkage |
| T4538 | 3740-3743 | DT | denotes | the |
| T4537 | 3737-3739 | IN | denotes | by |
| T4536 | 3727-3736 | VB | denotes | supported |
| T4535 | 3722-3726 | VB | denotes | been |
| T4534 | 3718-3721 | VB | denotes | has |
| T4533 | 3710-3717 | NN | denotes | process |
| T4532 | 3699-3709 | JJ | denotes | autoimmune |
| T4531 | 3694-3698 | DT | denotes | this |
| T4530 | 3691-3693 | IN | denotes | of |
| T4529 | 3678-3690 | NN | denotes | significance |
| T4528 | 3674-3677 | DT | denotes | The |
| T4527 | 3670-3672 | NN | denotes | RA |
| T4526 | 3667-3669 | IN | denotes | in |
| T4525 | 3665-3666 | -COMMA- | denotes | , |
| T4524 | 3656-3665 | NN | denotes | signaling |
| T4523 | 3642-3655 | JJ | denotes | costimulatory |
| T4522 | 3628-3641 | JJ | denotes | CD28-mediated |
| T4521 | 3623-3627 | IN | denotes | with |
| T4520 | 3611-3622 | NN | denotes | conjunction |
| T4519 | 3608-3610 | IN | denotes | in |
| T4518 | 3606-3607 | -COMMA- | denotes | , |
| T4517 | 3598-3606 | NN | denotes | antigens |
| T4516 | 3584-3597 | JJ | denotes | arthritogenic |
| T4515 | 3581-3583 | IN | denotes | by |
| T4514 | 3571-3580 | VB | denotes | activated |
| T4513 | 3568-3570 | VB | denotes | be |
| T4512 | 3564-3567 | MD | denotes | may |
| T4511 | 3558-3563 | NN | denotes | cells |
| T4510 | 3556-3557 | NN | denotes | T |
| T4509 | 3551-3555 | JJ | denotes | CD4+ |
| T4508 | 3548-3549 | -RRB- | denotes | ] |
| T4507 | 3546-3548 | CD | denotes | 15 |
| T4506 | 3545-3546 | -LRB- | denotes | [ |
| T4505 | 3538-3544 | NN | denotes | factor |
| T4504 | 3519-3537 | JJ | denotes | colony-stimulating |
| T4503 | 3496-3518 | JJ | denotes | granulocyte–macrophage |
| T4502 | 3492-3495 | CC | denotes | and |
| T4501 | 3490-3491 | -COMMA- | denotes | , |
| T4500 | 3486-3490 | NN | denotes | IL-1 |
| T4499 | 3484-3485 | -COMMA- | denotes | , |
| T4498 | 3479-3484 | NN | denotes | TNF-α |
| T4497 | 3476-3478 | IN | denotes | of |
| T4496 | 3467-3475 | NN | denotes | presence |
| T4495 | 3463-3466 | DT | denotes | the |
| T4085 | 892-895 | IN | denotes | for |
| T4084 | 878-891 | JJ | denotes | indispensable |
| T4083 | 875-877 | VB | denotes | is |
| T4082 | 869-874 | NN | denotes | STAT3 |
| T4081 | 867-868 | -COMMA- | denotes | , |
| T4080 | 855-867 | RB | denotes | Intriguingly |
| T4079 | 840-853 | NN | denotes | transcription |
| T4078 | 835-839 | NN | denotes | gene |
| T4077 | 826-834 | VB | denotes | modulate |
| T4076 | 822-825 | CC | denotes | and |
| T4075 | 820-821 | -COMMA- | denotes | , |
| T4074 | 813-820 | NN | denotes | nucleus |
| T4073 | 809-812 | DT | denotes | the |
| T4072 | 804-808 | IN | denotes | into |
| T4071 | 792-803 | VB | denotes | translocate |
| T4070 | 784-791 | RB | denotes | rapidly |
| T4069 | 782-783 | -COMMA- | denotes | , |
| T4068 | 770-782 | NN | denotes | heterodimers |
| T4067 | 767-769 | CC | denotes | or |
| T4066 | 756-766 | NN | denotes | homodimers |
| T4065 | 751-755 | VB | denotes | form |
| T4064 | 742-750 | NN | denotes | proteins |
| T4063 | 736-741 | NN | denotes | STAT3 |
| T4062 | 732-735 | CC | denotes | and |
| T4061 | 726-731 | NN | denotes | STAT1 |
| T4060 | 724-725 | -COMMA- | denotes | , |
| T4059 | 709-724 | NN | denotes | phosphorylation |
| T4058 | 704-708 | IN | denotes | Upon |
| T4057 | 701-702 | -RRB- | denotes | ] |
| T4056 | 700-701 | CD | denotes | 3 |
| T4055 | 699-700 | -LRB- | denotes | [ |
| T4054 | 693-698 | NN | denotes | STAT1 |
| T4278 | 2127-2132 | NN | denotes | Tumor |
| T4277 | 2116-2125 | NN | denotes | cytokines |
| T4276 | 2100-2115 | JJ | denotes | proinflammatory |
| T4275 | 2097-2099 | IN | denotes | of |
| T4274 | 2090-2096 | NN | denotes | source |
| T4273 | 2080-2089 | JJ | denotes | important |
| T4272 | 2077-2079 | DT | denotes | an |
| T4271 | 2073-2076 | VB | denotes | are |
| T4270 | 2061-2072 | NN | denotes | fibroblasts |
| T4053 | 689-692 | CC | denotes | and |
| T4052 | 687-688 | CD | denotes | 3 |
| T4051 | 685-686 | -RRB- | denotes | ) |
| T4050 | 681-685 | NN | denotes | STAT |
| T4049 | 680-681 | -LRB- | denotes | ( |
| T4048 | 666-679 | NN | denotes | transcription |
| T4047 | 663-665 | IN | denotes | of |
| T4046 | 653-662 | NN | denotes | activator |
| T4045 | 649-652 | CC | denotes | and |
| T4044 | 638-648 | NN | denotes | transducer |
| T4043 | 631-637 | NN | denotes | signal |
| T4042 | 623-630 | NN | denotes | factors |
| T4041 | 607-622 | JJ | denotes | transcriptional |
| T4040 | 600-606 | JJ | denotes | latent |
| T4039 | 596-599 | DT | denotes | the |
| T4038 | 593-595 | IN | denotes | of |
| T4037 | 582-592 | NN | denotes | activation |
| T4036 | 578-581 | CC | denotes | and |
| T4035 | 562-577 | NN | denotes | phosphorylation |
| T4034 | 553-561 | NN | denotes | tyrosine |
| T4033 | 545-552 | VB | denotes | induces |
| T4032 | 539-544 | NN | denotes | IL-10 |
| T4031 | 536-537 | -RRB- | denotes | ] |
| T4030 | 535-536 | CD | denotes | 2 |
| T4029 | 534-535 | -LRB- | denotes | [ |
| T4028 | 521-533 | RB | denotes | respectively |
| T4027 | 519-520 | -COMMA- | denotes | , |
| T4026 | 513-519 | NN | denotes | IL-10R |
| T4025 | 511-512 | CD | denotes | 2 |
| T4024 | 506-510 | NN | denotes | type |
| T4023 | 502-505 | CC | denotes | and |
| T4022 | 494-501 | NN | denotes | IL-10R1 |
| T4021 | 489-493 | IN | denotes | with |
| T4020 | 478-488 | VB | denotes | associated |
| T4019 | 463-477 | RB | denotes | constitutively |
| T4018 | 459-462 | VB | denotes | are |
| T4017 | 453-458 | WDT | denotes | which |
| T4016 | 451-452 | -COMMA- | denotes | , |
| T4015 | 447-451 | NN | denotes | Tyk2 |
| T4014 | 443-446 | CC | denotes | and |
| T4013 | 438-442 | NN | denotes | Jak1 |
| T4012 | 430-437 | NN | denotes | kinases |
| T4011 | 421-429 | NN | denotes | tyrosine |
| T4010 | 414-420 | NN | denotes | family |
| T4009 | 412-413 | -RRB- | denotes | ) |
| T4008 | 409-412 | NN | denotes | JAK |
| T4007 | 408-409 | -LRB- | denotes | ( |
| T4006 | 401-407 | NN | denotes | kinase |
| T4005 | 395-400 | NN | denotes | Janus |
| T4004 | 391-394 | DT | denotes | the |
| T4003 | 383-390 | VB | denotes | engages |
| T4002 | 376-382 | NN | denotes | IL-10R |
| T4001 | 372-375 | CC | denotes | and |
| T4000 | 366-371 | NN | denotes | IL-10 |
| T3999 | 363-365 | IN | denotes | of |
| T3998 | 351-362 | NN | denotes | interaction |
| T3997 | 347-350 | DT | denotes | The |
| T3996 | 344-345 | -RRB- | denotes | ] |
| T3995 | 343-344 | CD | denotes | 1 |
| T3994 | 342-343 | -LRB- | denotes | [ |
| T3956 | 115-123 | NN | denotes | function |
| T3955 | 111-114 | CC | denotes | and |
| T3954 | 100-110 | NN | denotes | production |
| T3953 | 96-99 | DT | denotes | the |
| T3952 | 85-95 | VB | denotes | inhibiting |
| T3993 | 335-341 | NN | denotes | IL-10R |
| T3992 | 333-334 | CD | denotes | 2 |
| T3991 | 328-332 | NN | denotes | type |
| T3990 | 318-327 | NN | denotes | component |
| T3989 | 308-317 | JJ | denotes | accessory |
| T3988 | 304-307 | DT | denotes | the |
| T3987 | 300-303 | CC | denotes | and |
| T3986 | 298-299 | -RRB- | denotes | ) |
| T3985 | 291-298 | NN | denotes | IL-10R1 |
| T3984 | 290-291 | -LRB- | denotes | ( |
| T3983 | 283-289 | NN | denotes | IL-10R |
| T3982 | 281-282 | CD | denotes | 1 |
| T3981 | 276-280 | NN | denotes | type |
| T3980 | 266-275 | NN | denotes | component |
| T3979 | 251-265 | JJ | denotes | ligand-binding |
| T3978 | 243-250 | JJ | denotes | primary |
| T3977 | 239-242 | DT | denotes | the |
| T3976 | 237-238 | -COMMA- | denotes | , |
| T3975 | 229-237 | NN | denotes | subunits |
| T3974 | 225-228 | CD | denotes | two |
| T3973 | 222-224 | IN | denotes | of |
| T3972 | 213-221 | VB | denotes | composed |
| T3971 | 210-212 | VB | denotes | is |
| T3970 | 205-209 | WDT | denotes | that |
| T3969 | 197-204 | NN | denotes | complex |
| T3968 | 195-196 | -RRB- | denotes | ) |
| T3967 | 189-195 | NN | denotes | IL-10R |
| T3966 | 188-189 | -LRB- | denotes | ( |
| T3965 | 179-187 | NN | denotes | receptor |
| T3964 | 173-178 | NN | denotes | IL-10 |
| T3963 | 169-172 | DT | denotes | the |
| T3962 | 166-168 | TO | denotes | to |
| T3961 | 160-165 | VB | denotes | binds |
| T3960 | 154-159 | NN | denotes | IL-10 |
| T3959 | 143-152 | NN | denotes | cytokines |
| T3958 | 127-142 | JJ | denotes | proinflammatory |
| T3957 | 124-126 | IN | denotes | of |
| T3951 | 82-84 | IN | denotes | by |
| T3950 | 75-81 | RB | denotes | mainly |
| T3949 | 73-74 | -COMMA- | denotes | , |
| T3948 | 64-73 | NN | denotes | responses |
| T3947 | 51-63 | JJ | denotes | inflammatory |
| T3946 | 40-50 | VB | denotes | regulating |
| T3945 | 37-39 | IN | denotes | in |
| T3944 | 28-36 | NN | denotes | cytokine |
| T3943 | 24-27 | JJ | denotes | key |
| T3942 | 22-23 | DT | denotes | a |
| T3941 | 19-21 | VB | denotes | is |
| T3940 | 13-18 | NN | denotes | IL-10 |
| R1040 | T4050 | T4049 | arg2Of | STAT,( |
| R1041 | T4051 | T4049 | arg3Of | ),( |
| R1042 | T4053 | T4033 | arg2Of | and,induces |
| R1043 | T4054 | T4053 | arg2Of | STAT1,and |
| R1044 | T4054 | T4055 | arg1Of | STAT1,[ |
| R1045 | T4056 | T4055 | arg2Of | 3,[ |
| R1047 | T4057 | T4055 | arg3Of | ],[ |
| R1052 | T4059 | T4058 | arg2Of | phosphorylation,Upon |
| R1056 | T4061 | T4062 | arg1Of | STAT1,and |
| R1059 | T4063 | T4062 | arg2Of | STAT3,and |
| R1064 | T4064 | T4061 | arg1Of | proteins,STAT1 |
| R1073 | T3972 | T3994 | arg1Of | composed,[ |
| R1074 | T4064 | T4063 | arg1Of | proteins,STAT3 |
| R1075 | T4064 | T4065 | arg1Of | proteins,form |
| R1079 | T4064 | T4071 | arg1Of | proteins,translocate |
| R1080 | T4064 | T4077 | arg1Of | proteins,modulate |
| R1081 | T4065 | T4069 | arg1Of | form,"," |
| R1082 | T4066 | T4067 | arg1Of | homodimers,or |
| R1083 | T3983 | T3977 | arg1Of | IL-10R,the |
| R1084 | T3983 | T3978 | arg1Of | IL-10R,primary |
| R1085 | T4067 | T4065 | arg2Of | or,form |
| R1086 | T3983 | T3979 | arg1Of | IL-10R,ligand-binding |
| R1087 | T3983 | T3980 | arg1Of | IL-10R,component |
| R1088 | T3983 | T3981 | arg1Of | IL-10R,type |
| R1089 | T3983 | T3982 | arg1Of | IL-10R,1 |
| R1090 | T3983 | T3984 | arg1Of | IL-10R,( |
| R1091 | T3983 | T3987 | arg1Of | IL-10R,and |
| R1092 | T3985 | T3984 | arg2Of | IL-10R1,( |
| R1093 | T3986 | T3984 | arg3Of | ),( |
| R1095 | T4068 | T4067 | arg2Of | heterodimers,or |
| R1096 | T4069 | T4058 | arg1Of | ",",Upon |
| R1097 | T3993 | T3987 | arg2Of | IL-10R,and |
| R1098 | T3993 | T3988 | arg1Of | IL-10R,the |
| R1099 | T3993 | T3989 | arg1Of | IL-10R,accessory |
| R1100 | T3993 | T3990 | arg1Of | IL-10R,component |
| R1101 | T3993 | T3991 | arg1Of | IL-10R,type |
| R1102 | T3993 | T3992 | arg1Of | IL-10R,2 |
| R1103 | T3995 | T3994 | arg2Of | 1,[ |
| R1104 | T4069 | T4060 | arg1Of | ",","," |
| R1105 | T3996 | T3994 | arg3Of | ],[ |
| R1106 | T4071 | T4072 | arg1Of | translocate,into |
| R1107 | T3998 | T3997 | arg1Of | interaction,The |
| R1108 | T3998 | T3999 | arg1Of | interaction,of |
| R1109 | T3998 | T4003 | arg1Of | interaction,engages |
| R1110 | T4000 | T4001 | arg1Of | IL-10,and |
| R1111 | T4071 | T4076 | arg1Of | translocate,and |
| R1112 | T4001 | T3999 | arg2Of | and,of |
| R1113 | T4002 | T4001 | arg2Of | IL-10R,and |
| R1114 | T4074 | T4072 | arg2Of | nucleus,into |
| R1115 | T4003 | T4029 | arg1Of | engages,[ |
| R1116 | T4006 | T4005 | arg1Of | kinase,Janus |
| R1117 | T4006 | T4007 | arg1Of | kinase,( |
| R1118 | T4008 | T4007 | arg2Of | JAK,( |
| R1119 | T4009 | T4007 | arg3Of | ),( |
| R1120 | T4074 | T4073 | arg1Of | nucleus,the |
| R1121 | T4076 | T4069 | arg2Of | and,"," |
| R1122 | T4013 | T4014 | arg1Of | Jak1,and |
| R1123 | T4014 | T4003 | arg2Of | and,engages |
| R1124 | T4014 | T4004 | arg1Of | and,the |
| R1125 | T4014 | T4006 | arg1Of | and,kinase |
| R1126 | T4014 | T4010 | arg1Of | and,family |
| R1127 | T4014 | T4011 | arg1Of | and,tyrosine |
| R1128 | T4014 | T4012 | arg1Of | and,kinases |
| R1129 | T4014 | T4016 | arg1Of | and,"," |
| R1130 | T4014 | T4017 | arg1Of | and,which |
| R1131 | T4014 | T4018 | arg1Of | and,are |
| R1132 | T4014 | T4020 | arg2Of | and,associated |
| R1133 | T4014 | T4027 | arg1Of | and,"," |
| R1134 | T4014 | T4028 | arg1Of | and,respectively |
| R1135 | T4015 | T4014 | arg2Of | Tyk2,and |
| R1136 | T4076 | T4070 | arg1Of | and,rapidly |
| R1137 | T4020 | T4018 | arg2Of | associated,are |
| R1138 | T4020 | T4019 | arg1Of | associated,constitutively |
| R1139 | T4020 | T4021 | arg1Of | associated,with |
| R1140 | T4076 | T4075 | arg1Of | and,"," |
| R1141 | T4022 | T4023 | arg1Of | IL-10R1,and |
| R1142 | T4023 | T4021 | arg2Of | and,with |
| R1143 | T4077 | T4076 | arg2Of | modulate,and |
| R1144 | T4026 | T4023 | arg2Of | IL-10R,and |
| R1145 | T4026 | T4024 | arg1Of | IL-10R,type |
| R1146 | T4026 | T4025 | arg1Of | IL-10R,2 |
| R1147 | T4079 | T4077 | arg2Of | transcription,modulate |
| R1148 | T4030 | T4029 | arg2Of | 2,[ |
| R1149 | T4079 | T4078 | arg1Of | transcription,gene |
| R1150 | T4031 | T4029 | arg3Of | ],[ |
| R1151 | T4032 | T4033 | arg1Of | IL-10,induces |
| R1152 | T4082 | T4083 | arg1Of | STAT3,is |
| R1153 | T4035 | T4034 | arg1Of | phosphorylation,tyrosine |
| R1154 | T4035 | T4036 | arg1Of | phosphorylation,and |
| R1155 | T4036 | T4038 | arg1Of | and,of |
| R1156 | T4082 | T4084 | arg1Of | STAT3,indispensable |
| R1157 | T4083 | T4080 | arg1Of | is,Intriguingly |
| R1158 | T4036 | T4053 | arg1Of | and,and |
| R1159 | T4037 | T4036 | arg2Of | activation,and |
| R1160 | T4083 | T4081 | arg1Of | is,"," |
| R1161 | T4083 | T4093 | arg1Of | is,[ |
| R1162 | T4084 | T4083 | arg2Of | indispensable,is |
| R1163 | T4084 | T4085 | arg1Of | indispensable,for |
| R1164 | T4088 | T4089 | arg1Of | anti-inflammatory,and |
| R1165 | T4044 | T4045 | arg1Of | transducer,and |
| R1166 | T4046 | T4045 | arg2Of | activator,and |
| R1167 | T4048 | T4038 | arg2Of | transcription,of |
| R1168 | T4048 | T4039 | arg1Of | transcription,the |
| R1169 | T4048 | T4040 | arg1Of | transcription,latent |
| R1170 | T4048 | T4041 | arg1Of | transcription,transcriptional |
| R1171 | T4048 | T4042 | arg1Of | transcription,factors |
| R1172 | T4048 | T4043 | arg1Of | transcription,signal |
| R1173 | T4048 | T4044 | arg1Of | transcription,transducer |
| R1174 | T4048 | T4046 | arg1Of | transcription,activator |
| R1175 | T4048 | T4047 | arg1Of | transcription,of |
| R1176 | T4048 | T4049 | arg1Of | transcription,( |
| R1177 | T4048 | T4052 | arg1Of | transcription,3 |
| R1178 | T4090 | T4089 | arg2Of | IL-6-derived,and |
| R1179 | T4092 | T4085 | arg2Of | responses,for |
| R1180 | T4148 | T4146 | arg2Of | family,as |
| R1181 | T4148 | T4147 | arg1Of | family,a |
| R1182 | T4148 | T4149 | arg1Of | family,of |
| R1183 | T4092 | T4086 | arg1Of | responses,both |
| R1184 | T4092 | T4087 | arg1Of | responses,IL-10-derived |
| R1185 | T4092 | T4088 | arg1Of | responses,anti-inflammatory |
| R1186 | T4153 | T4149 | arg2Of | inhibitors,of |
| R1187 | T4153 | T4150 | arg1Of | inhibitors,endogenous |
| R1188 | T4153 | T4151 | arg1Of | inhibitors,JAK |
| R1189 | T4153 | T4152 | arg1Of | inhibitors,kinase |
| R1190 | T4153 | T4154 | arg1Of | inhibitors,that |
| R1191 | T4153 | T4155 | arg1Of | inhibitors,can |
| R1192 | T4153 | T4156 | arg1Of | inhibitors,act |
| R1193 | T4092 | T4090 | arg1Of | responses,IL-6-derived |
| R1194 | T4156 | T4155 | arg2Of | act,can |
| R1195 | T4156 | T4157 | arg1Of | act,in |
| R1196 | T4092 | T4091 | arg1Of | responses,proinflammatory |
| R1197 | T4094 | T4093 | arg2Of | 4,[ |
| R1198 | T4161 | T4157 | arg2Of | loops,in |
| R1199 | T4161 | T4158 | arg1Of | loops,classic |
| R1200 | T4161 | T4159 | arg1Of | loops,feedback |
| R1201 | T4161 | T4160 | arg1Of | loops,inhibition |
| R1202 | T4163 | T4162 | arg1Of | but,"," |
| R1203 | T4095 | T4093 | arg3Of | ],[ |
| R1204 | T4165 | T4164 | arg1Of | roles,their |
| R1205 | T4165 | T4166 | arg1Of | roles,as |
| R1206 | T4165 | T4177 | arg1Of | roles,have |
| R1207 | T4165 | T4178 | arg1Of | roles,been |
| R1208 | T4165 | T4179 | arg2Of | roles,clarified |
| R1209 | T4096 | T4097 | arg1Of | Studies,of |
| R1210 | T4168 | T4166 | arg2Of | mediators,as |
| R1211 | T4168 | T4167 | arg1Of | mediators,the |
| R1212 | T4168 | T4169 | arg1Of | mediators,of |
| R1213 | T4168 | T4172 | arg1Of | mediators,by |
| R1214 | T4096 | T4101 | arg1Of | Studies,have |
| R1215 | T4171 | T4169 | arg2Of | inhibition,of |
| R1216 | T4171 | T4170 | arg1Of | inhibition,crosstalk |
| R1217 | T4096 | T4102 | arg1Of | Studies,shown |
| R1218 | T4173 | T4172 | arg2Of | opposing,by |
| R1219 | T4176 | T4173 | arg2Of | pathways,opposing |
| R1220 | T4176 | T4174 | arg1Of | pathways,cytokine |
| R1221 | T4176 | T4175 | arg1Of | pathways,signaling |
| R1222 | T4100 | T4097 | arg2Of | mice,of |
| R1223 | T4179 | T4163 | arg2Of | clarified,but |
| R1224 | T4179 | T4177 | arg2Of | clarified,have |
| R1225 | T4179 | T4178 | arg2Of | clarified,been |
| R1226 | T4179 | T4180 | arg1Of | clarified,[ |
| R1227 | T4181 | T4180 | arg2Of | 7,[ |
| R1228 | T4100 | T4098 | arg1Of | mice,cell-type-specific |
| R1229 | T4182 | T4180 | arg3Of | ],[ |
| R1230 | T4100 | T4099 | arg1Of | mice,STAT3-deficient |
| R1231 | T4102 | T4101 | arg2Of | shown,have |
| R1232 | T4184 | T4183 | arg1Of | studies,Recent |
| R1233 | T4184 | T4185 | arg1Of | studies,indicate |
| R1234 | T4105 | T4104 | arg1Of | activation,STAT3 |
| R1235 | T4187 | T4188 | arg1Of | SOCS3,plays |
| R1236 | T4187 | T4193 | arg1Of | SOCS3,regulating |
| R1237 | T4188 | T4185 | arg2Of | plays,indicate |
| R1238 | T4188 | T4186 | arg1Of | plays,that |
| R1239 | T4188 | T4192 | arg1Of | plays,in |
| R1240 | T4188 | T4201 | arg1Of | plays,"," |
| R1241 | T4188 | T4202 | arg1Of | plays,by |
| R1242 | T4105 | T4106 | arg1Of | activation,is |
| R1243 | T4105 | T4107 | arg1Of | activation,essential |
| R1244 | T4191 | T4188 | arg2Of | role,plays |
| R1245 | T4191 | T4189 | arg1Of | role,a |
| R1246 | T4191 | T4190 | arg1Of | role,key |
| R1247 | T4105 | T4121 | arg1Of | activation,is |
| R1248 | T4193 | T4192 | arg2Of | regulating,in |
| R1249 | T4105 | T4122 | arg1Of | activation,responsible |
| R1250 | T4196 | T4193 | arg2Of | action,regulating |
| R1251 | T4196 | T4194 | arg1Of | action,the |
| R1252 | T4196 | T4195 | arg1Of | action,divergent |
| R1253 | T4196 | T4197 | arg1Of | action,of |
| R1254 | T4106 | T4120 | arg1Of | is,but |
| R1255 | T4198 | T4199 | arg1Of | IL-10,and |
| R1256 | T4199 | T4197 | arg2Of | and,of |
| R1257 | T4200 | T4199 | arg2Of | IL-6,and |
| R1258 | T4107 | T4106 | arg2Of | essential,is |
| R1259 | T4107 | T4108 | arg1Of | essential,for |
| R1260 | T4204 | T4202 | arg2Of | blocking,by |
| R1261 | T4204 | T4203 | arg1Of | blocking,specifically |
| R1262 | T4111 | T4108 | arg2Of | reactions,for |
| R1263 | T4206 | T4205 | arg1Of | activation,STAT3 |
| R1264 | T4206 | T4207 | arg2Of | activation,induced |
| R1265 | T4206 | T4210 | arg1Of | activation,but |
| R1266 | T4209 | T4207 | arg1Of | IL-6,induced |
| R1267 | T4209 | T4208 | arg2Of | IL-6,by |
| R1268 | T4210 | T4204 | arg2Of | but,blocking |
| R1269 | T4210 | T4211 | arg1Of | but,not |
| R1270 | T4212 | T4210 | arg2Of | that,but |
| R1271 | T4212 | T4213 | arg2Of | that,induced |
| R1272 | T4213 | T4216 | arg1Of | induced,[ |
| R1273 | T4215 | T4213 | arg1Of | IL-10,induced |
| R1274 | T4215 | T4214 | arg2Of | IL-10,by |
| R1275 | T4111 | T4109 | arg1Of | reactions,IL-10-mediated |
| R1276 | T4217 | T4216 | arg2Of | "8,9",[ |
| R1277 | T4111 | T4110 | arg1Of | reactions,anti-inflammatory |
| R1278 | T4218 | T4216 | arg3Of | ],[ |
| R1279 | T4111 | T4112 | arg1Of | reactions,in |
| R1280 | T4113 | T4114 | arg1Of | macrophages,and |
| R1281 | T4221 | T4219 | arg1Of | membrane,The |
| R1282 | T4221 | T4220 | arg1Of | membrane,synovial |
| R1283 | T4221 | T4222 | arg1Of | membrane,of |
| R1284 | T4221 | T4228 | arg1Of | membrane,is |
| R1285 | T4221 | T4229 | arg2Of | membrane,characterized |
| R1286 | T4224 | T4222 | arg2Of | arthritis,of |
| R1287 | T4224 | T4223 | arg1Of | arthritis,rheumatoid |
| R1288 | T4224 | T4225 | arg1Of | arthritis,( |
| R1289 | T4114 | T4112 | arg2Of | and,in |
| R1290 | T4226 | T4225 | arg2Of | RA,( |
| R1291 | T4227 | T4225 | arg3Of | ),( |
| R1292 | T4114 | T4116 | arg1Of | and,[ |
| R1293 | T4229 | T4228 | arg2Of | characterized,is |
| R1294 | T4115 | T4114 | arg2Of | neutrophils,and |
| R1295 | T4232 | T4229 | arg1Of | infiltrate,characterized |
| R1296 | T4232 | T4230 | arg2Of | infiltrate,by |
| R1297 | T4232 | T4231 | arg1Of | infiltrate,an |
| R1298 | T4232 | T4233 | arg1Of | infiltrate,of |
| R1299 | T4117 | T4116 | arg2Of | 5,[ |
| R1300 | T4235 | T4233 | arg2Of | variety,of |
| R1301 | T4235 | T4234 | arg1Of | variety,a |
| R1302 | T4235 | T4236 | arg1Of | variety,of |
| R1303 | T4118 | T4116 | arg3Of | ],[ |
| R1304 | T4238 | T4236 | arg2Of | cells,of |
| R1305 | T4238 | T4237 | arg1Of | cells,inflammatory |
| R1306 | T4238 | T4239 | arg1Of | cells,"," |
| R1307 | T4238 | T4241 | arg1Of | cells,as |
| R1308 | T4241 | T4240 | arg1Of | as,such |
| R1309 | T4120 | T4102 | arg2Of | but,shown |
| R1310 | T4242 | T4243 | arg1Of | lymphocytes,"," |
| R1311 | T4120 | T4103 | arg1Of | but,that |
| R1312 | T4120 | T4119 | arg1Of | but,"," |
| R1313 | T4243 | T4246 | arg1Of | ",",and |
| R1314 | T4120 | T4131 | arg1Of | but,[ |
| R1315 | T4244 | T4243 | arg2Of | macrophages,"," |
| R1316 | T4121 | T4120 | arg2Of | is,but |
| R1317 | T4246 | T4241 | arg2Of | and,as |
| R1318 | T4246 | T4245 | arg1Of | and,"," |
| R1319 | T4246 | T4249 | arg1Of | and,"," |
| R1320 | T4246 | T4251 | arg1Of | and,with |
| R1321 | T4122 | T4121 | arg2Of | responsible,is |
| R1322 | T4248 | T4246 | arg2Of | cells,and |
| R1323 | T4248 | T4247 | arg1Of | cells,dendritic |
| R1324 | T4251 | T4250 | arg1Of | with,together |
| R1325 | T4122 | T4123 | arg1Of | responsible,for |
| R1326 | T4252 | T4251 | arg2Of | proliferation,with |
| R1327 | T4252 | T4253 | arg1Of | proliferation,of |
| R1328 | T4125 | T4123 | arg2Of | prevention,for |
| R1329 | T4256 | T4253 | arg2Of | cells,of |
| R1330 | T4256 | T4254 | arg1Of | cells,synovial |
| R1331 | T4256 | T4255 | arg1Of | cells,fibroblast-like |
| R1332 | T4125 | T4124 | arg1Of | prevention,IL-6-mediated |
| R1333 | T4125 | T4126 | arg1Of | prevention,of |
| R1334 | T4258 | T4257 | arg1Of | cytokines,Numerous |
| R1335 | T4258 | T4259 | arg1Of | cytokines,are |
| R1336 | T4258 | T4260 | arg2Of | cytokines,overproduced |
| R1337 | T4260 | T4259 | arg2Of | overproduced,are |
| R1338 | T4260 | T4261 | arg1Of | overproduced,in |
| R1339 | T4260 | T4266 | arg1Of | overproduced,and |
| R1340 | T4125 | T4128 | arg1Of | prevention,in |
| R1341 | T4127 | T4126 | arg2Of | apoptosis,of |
| R1342 | T4264 | T4261 | arg2Of | joint,in |
| R1343 | T4264 | T4262 | arg1Of | joint,the |
| R1344 | T4264 | T4263 | arg1Of | joint,inflamed |
| R1345 | T4266 | T4265 | arg1Of | and,"," |
| R1346 | T4130 | T4128 | arg2Of | cells,in |
| R1347 | T4267 | T4268 | arg1Of | macrophages,and |
| R1348 | T4130 | T4129 | arg1Of | cells,T |
| R1349 | T4268 | T4271 | arg1Of | and,are |
| R1350 | T4132 | T4131 | arg2Of | 6,[ |
| R1351 | T4270 | T4268 | arg2Of | fibroblasts,and |
| R1352 | T4270 | T4269 | arg1Of | fibroblasts,synovial |
| R1353 | T4271 | T4266 | arg2Of | are,and |
| R1354 | T4133 | T4131 | arg3Of | ],[ |
| R1355 | T4274 | T4271 | arg2Of | source,are |
| R1356 | T4274 | T4272 | arg1Of | source,an |
| R1357 | T4274 | T4273 | arg1Of | source,important |
| R1358 | T4274 | T4275 | arg1Of | source,of |
| R1359 | T4135 | T4134 | arg1Of | suppressor,The |
| R1360 | T4277 | T4275 | arg2Of | cytokines,of |
| R1361 | T4277 | T4276 | arg1Of | cytokines,proinflammatory |
| R1362 | T4135 | T4136 | arg1Of | suppressor,of |
| R1363 | T4281 | T4278 | arg1Of | alpha,Tumor |
| R1364 | T4281 | T4279 | arg1Of | alpha,necrosis |
| R1365 | T4281 | T4280 | arg1Of | alpha,factor |
| R1366 | T4281 | T4282 | arg1Of | alpha,( |
| R1367 | T4281 | T4285 | arg1Of | alpha,and |
| R1368 | T4283 | T4282 | arg2Of | TNF-α,( |
| R1369 | T4284 | T4282 | arg3Of | ),( |
| R1370 | T4285 | T4293 | arg1Of | and,are |
| R1371 | T4285 | T4294 | arg1Of | and,crucial |
| R1372 | T4286 | T4285 | arg2Of | IL-1,and |
| R1373 | T4286 | T4287 | arg1Of | IL-1,"," |
| R1374 | T4135 | T4143 | arg1Of | suppressor,have |
| R1375 | T4135 | T4144 | arg1Of | suppressor,been |
| R1376 | T4135 | T4145 | arg2Of | suppressor,identified |
| R1377 | T4140 | T4139 | arg2Of | SOCS,( |
| R1378 | T4291 | T4287 | arg2Of | products,"," |
| R1379 | T4291 | T4288 | arg1Of | products,two |
| R1380 | T4291 | T4289 | arg1Of | products,major |
| R1381 | T4291 | T4290 | arg1Of | products,macrophage |
| R1382 | T4293 | T4292 | arg1Of | are,"," |
| R1383 | T4293 | T4305 | arg1Of | are,and |
| R1384 | T4294 | T4293 | arg2Of | crucial,are |
| R1385 | T4294 | T4295 | arg1Of | crucial,in |
| R1386 | T4297 | T4295 | arg2Of | process,in |
| R1387 | T4297 | T4296 | arg1Of | process,the |
| R1388 | T4297 | T4298 | arg1Of | process,of |
| R1389 | T4300 | T4299 | arg1Of | inflammation,chronic |
| R1390 | T4300 | T4301 | arg1Of | inflammation,and |
| R1391 | T4141 | T4139 | arg3Of | ),( |
| R1392 | T4301 | T4298 | arg2Of | and,of |
| R1393 | T4303 | T4301 | arg2Of | destruction,and |
| R1394 | T4303 | T4302 | arg1Of | destruction,joint |
| R1395 | T4142 | T4136 | arg2Of | proteins,of |
| R1396 | T4305 | T4304 | arg1Of | and,"," |
| R1397 | T4306 | T4307 | arg1Of | they,give |
| R1398 | T4142 | T4137 | arg1Of | proteins,cytokine |
| R1399 | T4307 | T4305 | arg2Of | give,and |
| R1400 | T4142 | T4138 | arg1Of | proteins,signaling |
| R1401 | T4308 | T4307 | arg2Of | rise,give |
| R1402 | T4308 | T4309 | arg1Of | rise,to |
| R1403 | T4142 | T4139 | arg1Of | proteins,( |
| R1404 | T4145 | T4143 | arg2Of | identified,have |
| R1405 | T4311 | T4310 | arg1Of | components,effector |
| R1406 | T4311 | T4312 | arg1Of | components,"," |
| R1407 | T4311 | T4313 | arg1Of | components,including |
| R1408 | T4311 | T4329 | arg1Of | components,and |
| R1409 | T4316 | T4314 | arg1Of | cytokines,other |
| R1410 | T4316 | T4315 | arg1Of | cytokines,inflammatory |
| R1411 | T4316 | T4317 | arg1Of | cytokines,"," |
| R1412 | T4317 | T4319 | arg1Of | ",","," |
| R1413 | T4145 | T4144 | arg2Of | identified,been |
| R1414 | T4318 | T4317 | arg2Of | chemokines,"," |
| R1415 | T4145 | T4146 | arg1Of | identified,as |
| R1416 | T4319 | T4322 | arg1Of | ",","," |
| R1417 | T4145 | T4163 | arg1Of | identified,but |
| R1418 | T4340 | T4337 | arg2Of | cytokine,is |
| R1419 | T4321 | T4319 | arg2Of | factors,"," |
| R1420 | T4321 | T4320 | arg1Of | factors,growth |
| R1421 | T4322 | T4325 | arg1Of | ",","," |
| R1422 | T4324 | T4322 | arg2Of | proteases,"," |
| R1423 | T4324 | T4323 | arg1Of | proteases,matrix |
| R1424 | T4325 | T4313 | arg2Of | ",",including |
| R1425 | T4327 | T4325 | arg2Of | oxide,"," |
| R1426 | T4327 | T4326 | arg1Of | oxide,nitric |
| R1427 | T4329 | T4309 | arg2Of | and,to |
| R1428 | T4329 | T4328 | arg1Of | and,"," |
| R1429 | T4340 | T4338 | arg1Of | cytokine,a |
| R1430 | T4340 | T4339 | arg1Of | cytokine,pleiotropic |
| R1431 | T4340 | T4341 | arg2Of | cytokine,produced |
| R1432 | T4332 | T4329 | arg2Of | species,and |
| R1433 | T4332 | T4330 | arg1Of | species,reactive |
| R1434 | T4332 | T4331 | arg1Of | species,oxygen |
| R1435 | T4332 | T4333 | arg1Of | species,[ |
| R1436 | T4334 | T4333 | arg2Of | 10,[ |
| R1437 | T4335 | T4333 | arg3Of | ],[ |
| R1438 | T4341 | T4342 | arg1Of | produced,substantially |
| R1439 | T4336 | T4337 | arg1Of | IL-6,is |
| R1440 | T4345 | T4341 | arg1Of | fibroblasts,produced |
| R1441 | T4337 | T4347 | arg1Of | is,and |
| R1442 | T4345 | T4343 | arg2Of | fibroblasts,by |
| R1443 | T4345 | T4344 | arg2Of | fibroblasts,activated |
| R1444 | T4347 | T4346 | arg1Of | and,"," |
| R1445 | T4438 | T4437 | arg2Of | addition,In |
| R1446 | T4350 | T4348 | arg1Of | actions,its |
| R1447 | T4442 | T4440 | arg1Of | action,the |
| R1448 | T4442 | T4441 | arg1Of | action,anti-inflammatory |
| R1449 | T4442 | T4443 | arg1Of | action,of |
| R1450 | T4442 | T4445 | arg1Of | action,appears |
| R1451 | T4442 | T4447 | arg1Of | action,be |
| R1452 | T4442 | T4448 | arg2Of | action,modulated |
| R1453 | T4444 | T4443 | arg2Of | IL-10,of |
| R1454 | T4445 | T4437 | arg1Of | appears,In |
| R1455 | T4445 | T4439 | arg1Of | appears,"," |
| R1456 | T4350 | T4349 | arg1Of | actions,proinflammatory |
| R1457 | T4350 | T4351 | arg1Of | actions,include |
| R1458 | T4351 | T4347 | arg2Of | include,and |
| R1459 | T4448 | T4445 | arg2Of | modulated,appears |
| R1460 | T4448 | T4446 | arg1Of | modulated,to |
| R1461 | T4448 | T4447 | arg2Of | modulated,be |
| R1462 | T4448 | T4449 | arg1Of | modulated,at |
| R1463 | T4448 | T4455 | arg1Of | modulated,during |
| R1464 | T4451 | T4449 | arg2Of | level,at |
| R1465 | T4451 | T4450 | arg1Of | level,the |
| R1466 | T4451 | T4452 | arg1Of | level,of |
| R1467 | T4352 | T4351 | arg2Of | simulating,include |
| R1468 | T4454 | T4452 | arg2Of | transduction,of |
| R1469 | T4454 | T4453 | arg1Of | transduction,signal |
| R1470 | T4457 | T4455 | arg2Of | inflammation,during |
| R1471 | T4457 | T4456 | arg1Of | inflammation,chronic |
| R1472 | T4459 | T4458 | arg1Of | signaling,IL-10 |
| R1473 | T4459 | T4460 | arg1Of | signaling,is |
| R1474 | T4459 | T4461 | arg2Of | signaling,impaired |
| R1475 | T4352 | T4371 | arg1Of | simulating,[ |
| R1476 | T4461 | T4460 | arg2Of | impaired,is |
| R1477 | T4461 | T4462 | arg1Of | impaired,in |
| R1478 | T4355 | T4352 | arg2Of | response,simulating |
| R1479 | T4463 | T4462 | arg2Of | macrophages,in |
| R1480 | T4463 | T4464 | arg1Of | macrophages,upon |
| R1481 | T4466 | T4464 | arg2Of | exposure,upon |
| R1482 | T4466 | T4465 | arg1Of | exposure,chronic |
| R1483 | T4466 | T4467 | arg1Of | exposure,to |
| R1484 | T4355 | T4353 | arg1Of | response,the |
| R1485 | T4469 | T4468 | arg1Of | cytokines,proinflammatory |
| R1486 | T4469 | T4471 | arg1Of | cytokines,as |
| R1487 | T4469 | T4475 | arg1Of | cytokines,and |
| R1488 | T4355 | T4354 | arg1Of | response,acute-phase |
| R1489 | T4471 | T4470 | arg1Of | as,such |
| R1490 | T4355 | T4356 | arg1Of | response,"," |
| R1491 | T4472 | T4473 | arg1Of | TNF-α,and |
| R1492 | T4358 | T4357 | arg1Of | maturation,B-cell |
| R1493 | T4473 | T4471 | arg2Of | and,as |
| R1494 | T4474 | T4473 | arg2Of | IL-1,and |
| R1495 | T4475 | T4467 | arg2Of | and,to |
| R1496 | T4477 | T4475 | arg2Of | complexes,and |
| R1497 | T4477 | T4476 | arg1Of | complexes,immune |
| R1498 | T4477 | T4478 | arg1Of | complexes,[ |
| R1499 | T4358 | T4359 | arg1Of | maturation,into |
| R1500 | T4479 | T4478 | arg2Of | "13,14",[ |
| R1501 | T4358 | T4366 | arg1Of | maturation,and |
| R1502 | T4480 | T4478 | arg3Of | ],[ |
| R1503 | T4361 | T4360 | arg1Of | cells,plasma |
| R1504 | T4483 | T4481 | arg1Of | expression,Cell |
| R1505 | T4483 | T4482 | arg1Of | expression,surface |
| R1506 | T4483 | T4484 | arg1Of | expression,of |
| R1507 | T4483 | T4486 | arg1Of | expression,is |
| R1508 | T4483 | T4487 | arg2Of | expression,decreased |
| R1509 | T4485 | T4484 | arg2Of | IL-10R1,of |
| R1510 | T4361 | T4362 | arg1Of | cells,"," |
| R1511 | T4487 | T4486 | arg2Of | decreased,is |
| R1512 | T4487 | T4488 | arg1Of | decreased,in |
| R1513 | T4362 | T4359 | arg2Of | ",",into |
| R1514 | T4364 | T4362 | arg2Of | functions,"," |
| R1515 | T4364 | T4363 | arg1Of | functions,T-cell |
| R1516 | T4492 | T4488 | arg2Of | cells,in |
| R1517 | T4492 | T4489 | arg1Of | cells,synovial |
| R1518 | T4492 | T4490 | arg1Of | cells,fluid |
| R1519 | T4492 | T4491 | arg1Of | cells,dendritic |
| R1520 | T4492 | T4493 | arg1Of | cells,due |
| R1521 | T4493 | T4494 | arg1Of | due,to |
| R1522 | T4496 | T4494 | arg2Of | presence,to |
| R1523 | T4496 | T4495 | arg1Of | presence,the |
| R1524 | T4496 | T4497 | arg1Of | presence,of |
| R1525 | T4366 | T4356 | arg2Of | and,"," |
| R1526 | T4498 | T4499 | arg1Of | TNF-α,"," |
| R1527 | T4499 | T4502 | arg1Of | ",",and |
| R1528 | T4500 | T4499 | arg2Of | IL-1,"," |
| R1529 | T4366 | T4365 | arg1Of | and,"," |
| R1530 | T4370 | T4366 | arg2Of | differentiation,and |
| R1531 | T4502 | T4497 | arg2Of | and,of |
| R1532 | T4502 | T4501 | arg1Of | and,"," |
| R1533 | T4505 | T4502 | arg2Of | factor,and |
| R1534 | T4505 | T4503 | arg1Of | factor,granulocyte–macrophage |
| R1535 | T4505 | T4504 | arg1Of | factor,colony-stimulating |
| R1536 | T4505 | T4506 | arg1Of | factor,[ |
| R1537 | T4507 | T4506 | arg2Of | 15,[ |
| R1538 | T4508 | T4506 | arg3Of | ],[ |
| R1539 | T4370 | T4367 | arg1Of | differentiation,hematopoietic |
| R1540 | T4511 | T4509 | arg1Of | cells,CD4+ |
| R1541 | T4511 | T4510 | arg1Of | cells,T |
| R1542 | T4511 | T4512 | arg1Of | cells,may |
| R1543 | T4511 | T4513 | arg1Of | cells,be |
| R1544 | T4511 | T4514 | arg2Of | cells,activated |
| R1545 | T4370 | T4368 | arg1Of | differentiation,precursor |
| R1546 | T4514 | T4512 | arg2Of | activated,may |
| R1547 | T4514 | T4513 | arg2Of | activated,be |
| R1548 | T4514 | T4515 | arg1Of | activated,by |
| R1549 | T4514 | T4518 | arg1Of | activated,"," |
| R1550 | T4514 | T4519 | arg1Of | activated,in |
| R1551 | T4514 | T4525 | arg1Of | activated,"," |
| R1552 | T4514 | T4526 | arg1Of | activated,in |
| R1553 | T4370 | T4369 | arg1Of | differentiation,cell |
| R1554 | T4517 | T4515 | arg2Of | antigens,by |
| R1555 | T4517 | T4516 | arg1Of | antigens,arthritogenic |
| R1556 | T4372 | T4371 | arg2Of | 11,[ |
| R1557 | T4520 | T4519 | arg2Of | conjunction,in |
| R1558 | T4520 | T4521 | arg1Of | conjunction,with |
| R1559 | T4373 | T4371 | arg3Of | ],[ |
| R1560 | T4377 | T4376 | arg1Of | cytokines,anti-inflammatory |
| R1561 | T4524 | T4521 | arg2Of | signaling,with |
| R1562 | T4524 | T4522 | arg1Of | signaling,CD28-mediated |
| R1563 | T4524 | T4523 | arg1Of | signaling,costimulatory |
| R1564 | T4527 | T4526 | arg2Of | RA,in |
| R1565 | T4529 | T4528 | arg1Of | significance,The |
| R1566 | T4529 | T4530 | arg1Of | significance,of |
| R1567 | T4529 | T4534 | arg1Of | significance,has |
| R1568 | T4529 | T4535 | arg1Of | significance,been |
| R1569 | T4529 | T4536 | arg2Of | significance,supported |
| R1570 | T4533 | T4530 | arg2Of | process,of |
| R1571 | T4533 | T4531 | arg1Of | process,this |
| R1572 | T4533 | T4532 | arg1Of | process,autoimmune |
| R1573 | T4377 | T4378 | arg1Of | cytokines,and |
| R1574 | T4378 | T4381 | arg1Of | and,are |
| R1575 | T4378 | T4383 | arg1Of | and,present |
| R1576 | T4536 | T4534 | arg2Of | supported,has |
| R1577 | T4380 | T4378 | arg2Of | inhibitors,and |
| R1578 | T4536 | T4535 | arg2Of | supported,been |
| R1579 | T4536 | T4576 | arg1Of | supported,"," |
| R1580 | T4536 | T4577 | arg1Of | supported,in |
| R1581 | T4380 | T4379 | arg1Of | inhibitors,cytokine |
| R1582 | T4381 | T4374 | arg1Of | are,However |
| R1583 | T4539 | T4538 | arg1Of | linkage,the |
| R1584 | T4539 | T4540 | arg1Of | linkage,of |
| R1585 | T4539 | T4549 | arg1Of | linkage,with |
| R1586 | T4539 | T4559 | arg1Of | linkage,by |
| R1587 | T4539 | T4568 | arg1Of | linkage,and |
| R1588 | T4381 | T4375 | arg1Of | are,"," |
| R1589 | T4381 | T4382 | arg1Of | are,also |
| R1590 | T4383 | T4381 | arg2Of | present,are |
| R1591 | T4545 | T4542 | arg1Of | antigens,MHC |
| R1592 | T4545 | T4543 | arg1Of | antigens,class |
| R1593 | T4545 | T4544 | arg1Of | antigens,II |
| R1594 | T4546 | T4547 | arg1Of | HLA-DRB1*0404,and |
| R1595 | T4547 | T4540 | arg2Of | and,of |
| R1596 | T4547 | T4541 | arg1Of | and,the |
| R1597 | T4547 | T4545 | arg1Of | and,antigens |
| R1598 | T4548 | T4547 | arg2Of | HLA-DRB1*0401,and |
| R1599 | T4383 | T4384 | arg1Of | present,in |
| R1600 | T4549 | T4558 | arg1Of | with,and |
| R1601 | T4386 | T4384 | arg2Of | quantities,in |
| R1602 | T4551 | T4550 | arg1Of | susceptibility,disease |
| R1603 | T4551 | T4552 | arg1Of | susceptibility,and |
| R1604 | T4552 | T4549 | arg2Of | and,with |
| R1605 | T4553 | T4552 | arg2Of | severity,and |
| R1606 | T4553 | T4554 | arg1Of | severity,[ |
| R1607 | T4555 | T4554 | arg2Of | "16,17",[ |
| R1608 | T4386 | T4385 | arg1Of | quantities,large |
| R1609 | T4556 | T4554 | arg3Of | ],[ |
| R1610 | T4386 | T4387 | arg1Of | quantities,in |
| R1611 | T4389 | T4387 | arg2Of | joints,in |
| R1612 | T4558 | T4557 | arg1Of | and,"," |
| R1613 | T4559 | T4558 | arg2Of | by,and |
| R1614 | T4562 | T4559 | arg2Of | expression,by |
| R1615 | T4562 | T4560 | arg1Of | expression,the |
| R1616 | T4562 | T4561 | arg1Of | expression,high-level |
| R1617 | T4562 | T4563 | arg1Of | expression,of |
| R1618 | T4389 | T4388 | arg1Of | joints,RA |
| R1619 | T4390 | T4391 | arg1Of | IL-10,"," |
| R1620 | T4567 | T4563 | arg2Of | molecules,of |
| R1621 | T4567 | T4564 | arg1Of | molecules,MHC |
| R1622 | T4567 | T4565 | arg1Of | molecules,class |
| R1623 | T4567 | T4566 | arg1Of | molecules,II |
| R1624 | T4568 | T4536 | arg1Of | and,supported |
| R1625 | T4568 | T4537 | arg2Of | and,by |
| R1626 | T4390 | T4392 | arg2Of | IL-10,produced |
| R1627 | T4390 | T4408 | arg1Of | IL-10,is |
| R1628 | T4571 | T4568 | arg2Of | ligands,and |
| R1629 | T4571 | T4569 | arg1Of | ligands,both |
| R1630 | T4571 | T4570 | arg1Of | ligands,CD28 |
| R1631 | T4571 | T4572 | arg1Of | ligands,"," |
| R1632 | T4573 | T4574 | arg1Of | CD80,and |
| R1633 | T4390 | T4410 | arg2Of | IL-10,known |
| R1634 | T4574 | T4572 | arg2Of | and,"," |
| R1635 | T4392 | T4393 | arg1Of | produced,by |
| R1636 | T4575 | T4574 | arg2Of | CD86,and |
| R1637 | T4392 | T4397 | arg1Of | produced,by |
| R1638 | T4393 | T4395 | arg1Of | by,and |
| R1639 | T4580 | T4577 | arg2Of | ST,in |
| R1640 | T4580 | T4578 | arg1Of | ST,the |
| R1641 | T4580 | T4579 | arg1Of | ST,inflamed |
| R1642 | T4580 | T4581 | arg1Of | ST,[ |
| R1643 | T4582 | T4581 | arg2Of | 18-20,[ |
| R1644 | T4583 | T4581 | arg3Of | ],[ |
| R1645 | T4394 | T4393 | arg2Of | macrophages,by |
| R1646 | T4397 | T4395 | arg2Of | by,and |
| R1647 | T4586 | T4584 | arg1Of | emergence,The |
| R1648 | T4586 | T4585 | arg1Of | emergence,continuing |
| R1649 | T4586 | T4587 | arg1Of | emergence,of |
| R1650 | T4586 | T4599 | arg1Of | emergence,may |
| R1651 | T4586 | T4600 | arg1Of | emergence,be |
| R1652 | T4586 | T4601 | arg1Of | emergence,crucial |
| R1653 | T4591 | T4587 | arg2Of | cells,of |
| R1654 | T4591 | T4588 | arg2Of | cells,activated |
| R1655 | T4591 | T4589 | arg1Of | cells,CD4+ |
| R1656 | T4591 | T4590 | arg1Of | cells,T |
| R1657 | T4397 | T4396 | arg1Of | by,partly |
| R1658 | T4594 | T4593 | arg1Of | though,even |
| R1659 | T4594 | T4596 | arg1Of | though,in |
| R1660 | T4399 | T4397 | arg2Of | cells,by |
| R1661 | T4595 | T4594 | arg2Of | few,though |
| R1662 | T4597 | T4596 | arg2Of | number,in |
| R1663 | T4399 | T4398 | arg1Of | cells,T |
| R1664 | T4399 | T4400 | arg1Of | cells,in |
| R1665 | T4600 | T4592 | arg1Of | be,"," |
| R1666 | T4600 | T4594 | arg1Of | be,though |
| R1667 | T4600 | T4598 | arg1Of | be,"," |
| R1668 | T4600 | T4599 | arg2Of | be,may |
| R1669 | T4601 | T4600 | arg2Of | crucial,be |
| R1670 | T4601 | T4602 | arg1Of | crucial,in |
| R1671 | T4603 | T4602 | arg2Of | sustaining,in |
| R1672 | T4403 | T4400 | arg2Of | tissue,in |
| R1673 | T4605 | T4603 | arg2Of | activation,sustaining |
| R1674 | T4605 | T4604 | arg1Of | activation,the |
| R1675 | T4605 | T4606 | arg1Of | activation,of |
| R1676 | T4605 | T4611 | arg1Of | activation,through |
| R1677 | T4605 | T4615 | arg1Of | activation,by |
| R1678 | T4403 | T4401 | arg1Of | tissue,the |
| R1679 | T4607 | T4608 | arg1Of | macrophages,and |
| R1680 | T4608 | T4606 | arg2Of | and,of |
| R1681 | T4403 | T4402 | arg1Of | tissue,synovial |
| R1682 | T4403 | T4404 | arg1Of | tissue,( |
| R1683 | T4610 | T4608 | arg2Of | fibroblasts,and |
| R1684 | T4610 | T4609 | arg1Of | fibroblasts,synovial |
| R1685 | T4405 | T4404 | arg2Of | ST,( |
| R1686 | T4614 | T4611 | arg2Of | signaling,through |
| R1687 | T4614 | T4612 | arg1Of | signaling,cell |
| R1688 | T4614 | T4613 | arg1Of | signaling,surface |
| R1689 | T4406 | T4404 | arg3Of | ),( |
| R1690 | T4616 | T4617 | arg1Of | means,of |
| R1691 | T4616 | T4626 | arg1Of | means,as |
| R1692 | T4410 | T4407 | arg1Of | known,"," |
| R1693 | T4620 | T4618 | arg1Of | CD69,cell |
| R1694 | T4620 | T4619 | arg1Of | CD69,surface |
| R1695 | T4620 | T4621 | arg1Of | CD69,and |
| R1696 | T4621 | T4617 | arg2Of | and,of |
| R1697 | T4622 | T4621 | arg2Of | CD11,and |
| R1698 | T4410 | T4408 | arg2Of | known,is |
| R1699 | T4410 | T4409 | arg1Of | known,best |
| R1700 | T4410 | T4411 | arg1Of | known,as |
| R1701 | T4626 | T4615 | arg2Of | as,by |
| R1702 | T4626 | T4623 | arg1Of | as,"," |
| R1703 | T4626 | T4624 | arg1Of | as,as |
| R1704 | T4626 | T4625 | arg1Of | as,well |
| R1705 | T4410 | T4421 | arg1Of | known,but |
| R1706 | T4628 | T4626 | arg2Of | release,as |
| R1707 | T4628 | T4627 | arg1Of | release,the |
| R1708 | T4628 | T4629 | arg1Of | release,of |
| R1709 | T4414 | T4411 | arg2Of | regulator,as |
| R1710 | T4414 | T4412 | arg1Of | regulator,a |
| R1711 | T4414 | T4413 | arg1Of | regulator,negative |
| R1712 | T4632 | T4629 | arg2Of | cytokines,of |
| R1713 | T4632 | T4630 | arg1Of | cytokines,proinflammatory |
| R1714 | T4632 | T4631 | arg1Of | cytokines,Th1 |
| R1715 | T4632 | T4634 | arg1Of | cytokines,as |
| R1716 | T4414 | T4415 | arg1Of | regulator,for |
| R1717 | T4634 | T4633 | arg1Of | as,such |
| R1718 | T4416 | T4417 | arg1Of | macrophage,and |
| R1719 | T4418 | T4417 | arg2Of | Th1,and |
| R1720 | T4636 | T4635 | arg1Of | gamma,interferon |
| R1721 | T4636 | T4637 | arg1Of | gamma,( |
| R1722 | T4638 | T4637 | arg2Of | IFN,( |
| R1723 | T4639 | T4637 | arg3Of | ),( |
| R1724 | T4640 | T4636 | arg1Of | -γ,gamma |
| R1725 | T4640 | T4641 | arg1Of | -γ,and |
| R1726 | T4641 | T4634 | arg2Of | and,as |
| R1727 | T4642 | T4641 | arg2Of | IL-17,and |
| R1728 | T4419 | T4415 | arg2Of | cells,for |
| R1729 | T4642 | T4643 | arg1Of | IL-17,[ |
| R1730 | T4644 | T4643 | arg2Of | "21,22",[ |
| R1731 | T4645 | T4643 | arg3Of | ],[ |
| R1732 | T4419 | T4416 | arg1Of | cells,macrophage |
| R1733 | T4419 | T4418 | arg1Of | cells,Th1 |
| R1734 | T4647 | T4646 | arg2Of | addition,In |
| R1735 | T4421 | T4420 | arg1Of | but,"," |
| R1736 | T4651 | T4649 | arg1Of | cells,CD4+ |
| R1737 | T4651 | T4650 | arg1Of | cells,T |
| R1738 | T4651 | T4652 | arg1Of | cells,could |
| R1739 | T4651 | T4653 | arg1Of | cells,stimulate |
| R1740 | T4653 | T4646 | arg1Of | stimulate,In |
| R1741 | T4653 | T4648 | arg1Of | stimulate,"," |
| R1742 | T4653 | T4652 | arg2Of | stimulate,could |
| R1743 | T4424 | T4422 | arg1Of | level,the |
| R1744 | T4655 | T4653 | arg2Of | production,stimulate |
| R1745 | T4655 | T4654 | arg1Of | production,B-cell |
| R1746 | T4655 | T4656 | arg1Of | production,of |
| R1747 | T4657 | T4656 | arg2Of | autoantibodies,of |
| R1748 | T4657 | T4659 | arg1Of | autoantibodies,as |
| R1749 | T4659 | T4658 | arg1Of | as,such |
| R1750 | T4424 | T4423 | arg1Of | level,expression |
| R1751 | T4661 | T4660 | arg1Of | factor,rheumatoid |
| R1752 | T4661 | T4662 | arg1Of | factor,and |
| R1753 | T4424 | T4425 | arg1Of | level,is |
| R1754 | T4662 | T4659 | arg2Of | and,as |
| R1755 | T4424 | T4426 | arg1Of | level,insufficient |
| R1756 | T4424 | T4428 | arg1Of | level,counterbalance |
| R1757 | T4425 | T4421 | arg2Of | is,but |
| R1758 | T4665 | T4662 | arg2Of | destruction,and |
| R1759 | T4665 | T4663 | arg1Of | destruction,osteoclast-mediated |
| R1760 | T4665 | T4664 | arg1Of | destruction,bone |
| R1761 | T4426 | T4425 | arg2Of | insufficient,is |
| R1762 | T4668 | T4666 | arg1Of | role,Their |
| R1763 | T4668 | T4667 | arg1Of | role,obligatory |
| R1764 | T4668 | T4669 | arg1Of | role,in |
| R1765 | T4668 | T4672 | arg1Of | role,was |
| R1766 | T4668 | T4674 | arg2Of | role,proved |
| R1767 | T4671 | T4669 | arg2Of | synovitis,in |
| R1768 | T4671 | T4670 | arg1Of | synovitis,RA |
| R1769 | T4428 | T4426 | arg2Of | counterbalance,insufficient |
| R1770 | T4674 | T4672 | arg2Of | proved,was |
| R1771 | T4674 | T4673 | arg1Of | proved,recently |
| R1772 | T4674 | T4675 | arg1Of | proved,by |
| R1773 | T4677 | T4675 | arg2Of | treatment,by |
| R1774 | T4677 | T4676 | arg1Of | treatment,successful |
| R1775 | T4677 | T4678 | arg1Of | treatment,of |
| R1776 | T4428 | T4427 | arg1Of | counterbalance,to |
| R1777 | T4680 | T4678 | arg2Of | disease,of |
| R1778 | T4680 | T4679 | arg1Of | disease,active |
| R1779 | T4428 | T4434 | arg1Of | counterbalance,[ |
| R1780 | T4430 | T4428 | arg2Of | cascade,counterbalance |
| R1781 | T4683 | T4674 | arg1Of | inhibition,proved |
| R1782 | T4683 | T4681 | arg2Of | inhibition,by |
| R1783 | T4683 | T4682 | arg1Of | inhibition,selective |
| R1784 | T4683 | T4684 | arg1Of | inhibition,of |
| R1785 | T4683 | T4687 | arg1Of | inhibition,with |
| R1786 | T4686 | T4684 | arg2Of | activation,of |
| R1787 | T4686 | T4685 | arg1Of | activation,T-cell |
| R1788 | T4430 | T4429 | arg1Of | cascade,the |
| R1789 | T4689 | T4687 | arg2Of | protein,with |
| R1790 | T4689 | T4688 | arg1Of | protein,fusion |
| R1791 | T4689 | T4690 | arg1Of | protein,of |
| R1792 | T4689 | T4699 | arg1Of | protein,"," |
| R1793 | T4689 | T4700 | arg1Of | protein,which |
| R1794 | T4689 | T4701 | arg1Of | protein,can |
| R1795 | T4689 | T4702 | arg1Of | protein,block |
| R1796 | T4430 | T4431 | arg1Of | cascade,of |
| R1797 | T4689 | T4711 | arg1Of | protein,binding |
| R1798 | T4433 | T4431 | arg2Of | events,of |
| R1799 | T4433 | T4432 | arg1Of | events,proinflammatory |
| R1800 | T4435 | T4434 | arg2Of | 12,[ |
| R1801 | T4696 | T4695 | arg2Of | CD152,( |
| R1802 | T4697 | T4695 | arg3Of | ),( |
| R1803 | T4698 | T4690 | arg2Of | -IgG,of |
| R1804 | T4698 | T4691 | arg1Of | -IgG,cytotoxic |
| R1805 | T4698 | T4692 | arg1Of | -IgG,T-cell-associated |
| R1806 | T4698 | T4693 | arg1Of | -IgG,antigen |
| R1807 | T4698 | T4694 | arg1Of | -IgG,4 |
| R1808 | T4698 | T4695 | arg1Of | -IgG,( |
| R1809 | T4436 | T4434 | arg3Of | ],[ |
| R1810 | T4702 | T4701 | arg2Of | block,can |
| R1811 | T4702 | T4710 | arg1Of | block,by |
| R1812 | T4702 | T4719 | arg1Of | block,[ |
| R1813 | T4729 | T4724 | arg2Of | response,blocks |
| R1814 | T4704 | T4702 | arg2Of | engagement,block |
| R1815 | T4704 | T4703 | arg1Of | engagement,the |
| R1816 | T4704 | T4705 | arg1Of | engagement,of |
| R1817 | T4704 | T4707 | arg1Of | engagement,on |
| R1818 | T4706 | T4705 | arg2Of | CD28,of |
| R1819 | T4709 | T4707 | arg2Of | cells,on |
| R1820 | T4709 | T4708 | arg1Of | cells,T |
| R1821 | T4729 | T4725 | arg1Of | response,the |
| R1822 | T4711 | T4710 | arg2Of | binding,by |
| R1823 | T4711 | T4712 | arg1Of | binding,to |
| R1824 | T4713 | T4714 | arg1Of | CD80,and |
| R1825 | T4714 | T4712 | arg2Of | and,to |
| R1826 | T4714 | T4716 | arg1Of | and,with |
| R1827 | T4715 | T4714 | arg2Of | CD86,and |
| R1828 | T4729 | T4726 | arg1Of | response,antigen-specific |
| R1829 | T4729 | T4727 | arg1Of | response,T-cell |
| R1830 | T4729 | T4728 | arg1Of | response,cytokine |
| R1831 | T4718 | T4716 | arg2Of | avidity,with |
| R1832 | T4718 | T4717 | arg1Of | avidity,high |
| R1833 | T4730 | T4742 | arg1Of | by,as |
| R1834 | T4720 | T4719 | arg2Of | 23,[ |
| R1835 | T4721 | T4719 | arg3Of | ],[ |
| R1836 | T4722 | T4724 | arg1Of | IL-10,blocks |
| R1837 | T4722 | T4731 | arg1Of | IL-10,inhibiting |
| R1838 | T4722 | T4745 | arg1Of | IL-10,downregulating |
| R1839 | T4731 | T4730 | arg2Of | inhibiting,by |
| R1840 | T4724 | T4723 | arg1Of | blocks,efficiently |
| R1841 | T4724 | T4730 | arg1Of | blocks,by |
| R1842 | T4724 | T4744 | arg1Of | blocks,by |
| R1843 | T4735 | T4731 | arg2Of | pathway,inhibiting |
| R1844 | T4735 | T4732 | arg1Of | pathway,the |
| R1845 | T4735 | T4733 | arg1Of | pathway,CD28 |
| R1846 | T4735 | T4734 | arg1Of | pathway,signaling |
| R1847 | T4735 | T4736 | arg1Of | pathway,[ |
| R1848 | T4737 | T4736 | arg2Of | 24,[ |
| R1850 | T4738 | T4736 | arg3Of | ],[ |
| R1852 | T4742 | T4739 | arg1Of | as,"," |
| R1855 | T4742 | T4740 | arg1Of | as,as |
| R1856 | T4742 | T4741 | arg1Of | as,well |
| R1857 | T4744 | T4742 | arg2Of | by,as |
| R1859 | T4744 | T4743 | arg1Of | by,indirectly |
| R1860 | T4745 | T4744 | arg2Of | downregulating,by |
| R1861 | T4747 | T4745 | arg2Of | function,downregulating |
| R1863 | T4747 | T4746 | arg1Of | function,the |
| R1864 | T4747 | T4748 | arg1Of | function,of |
| R1865 | T4750 | T4748 | arg2Of | cells,of |
| R1868 | T4750 | T4749 | arg1Of | cells,antigen-presenting |
| R1870 | T4752 | T4751 | arg1Of | elucidate,To |
| R1873 | T4754 | T4752 | arg2Of | resistance,elucidate |
| R1875 | T4754 | T4753 | arg1Of | resistance,the |
| R1876 | T4754 | T4755 | arg1Of | resistance,of |
| R1877 | T4754 | T4759 | arg1Of | resistance,to |
| R1879 | T4758 | T4755 | arg2Of | cells,of |
| R1883 | T4758 | T4756 | arg1Of | cells,CD4+ |
| R1885 | T4758 | T4757 | arg1Of | cells,T |
| R1886 | T4762 | T4759 | arg2Of | inhibition,to |
| R1889 | T4762 | T4760 | arg1Of | inhibition,this |
| R1890 | T4762 | T4761 | arg1Of | inhibition,direct |
| R1891 | T4762 | T4763 | arg1Of | inhibition,in |
| R1893 | T4764 | T4763 | arg2Of | RA,in |
| R1895 | T4766 | T4752 | arg1Of | we,elucidate |
| R1897 | T4766 | T4767 | arg1Of | we,investigated |
| R1898 | T4767 | T4751 | modOf | investigated,To |
| R1900 | T4767 | T4765 | arg1Of | investigated,"," |
| R1901 | T4769 | T4768 | arg1Of | production,the |
| R1903 | T4769 | T4770 | arg1Of | production,of |
| R1905 | T4769 | T4793 | arg1Of | production,and |
| R1906 | T4771 | T4770 | arg2Of | IFN-γ,of |
| R1909 | T4771 | T4772 | arg1Of | IFN-γ,after |
| R1910 | T4771 | T4777 | arg1Of | IFN-γ,in |
| R1912 | T4773 | T4774 | arg1Of | CD3,and |
| R1913 | T4775 | T4774 | arg2Of | CD28,and |
| R1915 | T4776 | T4772 | arg2Of | costimulation,after |
| R1916 | T4776 | T4773 | arg1Of | costimulation,CD3 |
| R1918 | T4776 | T4775 | arg1Of | costimulation,CD28 |
| R1919 | T4779 | T4777 | arg2Of | presence,in |
| R1921 | T4779 | T4778 | arg1Of | presence,the |
| R1922 | T4779 | T4780 | arg1Of | presence,of |
| R1924 | T4781 | T4780 | arg2Of | IL-10,of |
| R1925 | T4781 | T4782 | arg1Of | IL-10,"," |
| R1926 | T4784 | T4782 | arg2Of | induction,"," |
| R1927 | T4784 | T4783 | arg1Of | induction,the |
| R1928 | T4784 | T4785 | arg1Of | induction,of |
| R1929 | T4784 | T4790 | arg1Of | induction,by |
| R1930 | T4786 | T4787 | arg1Of | STAT1,and |
| R1931 | T4788 | T4787 | arg2Of | STAT3,and |
| R1933 | T4789 | T4785 | arg2Of | phosphorylation,of |
| R1935 | T4789 | T4786 | arg1Of | phosphorylation,STAT1 |
| R1936 | T4789 | T4788 | arg1Of | phosphorylation,STAT3 |
| R1938 | T4791 | T4790 | arg2Of | IL-10,by |
| R1939 | T4793 | T4767 | arg2Of | and,investigated |
| R1941 | T4793 | T4792 | arg1Of | and,"," |
| R1942 | T4795 | T4793 | arg2Of | expression,and |
| R1944 | T4795 | T4794 | arg1Of | expression,the |
| R1946 | T4795 | T4796 | arg1Of | expression,of |
| R1947 | T4795 | T4801 | arg1Of | expression,in |
| R1949 | T4795 | T4810 | arg1Of | expression,from |
| R1950 | T4797 | T4798 | arg1Of | SOCS1,and |
| R1953 | T4799 | T4798 | arg2Of | SOCS3,and |
| R1956 | T4800 | T4796 | arg2Of | mRNA,of |
| R1958 | T4800 | T4797 | arg1Of | mRNA,SOCS1 |
| R1959 | T4800 | T4799 | arg1Of | mRNA,SOCS3 |
| R1961 | T4805 | T4804 | arg2Of | PB,( |
| R1963 | T4806 | T4804 | arg3Of | ),( |
| R1964 | T4809 | T4801 | arg2Of | cells,in |
| R1965 | T4809 | T4802 | arg1Of | cells,peripheral |
| R1966 | T4809 | T4803 | arg1Of | cells,blood |
| R1967 | T4809 | T4804 | arg1Of | cells,( |
| R1969 | T4809 | T4807 | arg1Of | cells,CD4+ |
| R1970 | T4809 | T4808 | arg1Of | cells,T |
| R1972 | T4812 | T4810 | arg2Of | patients,from |
| R1975 | T4812 | T4811 | arg1Of | patients,RA |
| R1029 | T3940 | T3941 | arg1Of | IL-10,is |
| R1030 | T3944 | T3941 | arg2Of | cytokine,is |
| R1031 | T3944 | T3942 | arg1Of | cytokine,a |
| R1032 | T3944 | T3943 | arg1Of | cytokine,key |
| R1033 | T3944 | T3945 | arg1Of | cytokine,in |
| R1034 | T3946 | T3945 | arg2Of | regulating,in |
| R1035 | T3946 | T3949 | arg1Of | regulating,"," |
| R1036 | T3946 | T3951 | arg1Of | regulating,by |
| R1037 | T3948 | T3946 | arg2Of | responses,regulating |
| R1038 | T3948 | T3947 | arg1Of | responses,inflammatory |
| R1039 | T3951 | T3950 | arg1Of | by,mainly |
| R1046 | T3952 | T3951 | arg2Of | inhibiting,by |
| R1048 | T3954 | T3955 | arg1Of | production,and |
| R1049 | T3955 | T3952 | arg2Of | and,inhibiting |
| R1050 | T3955 | T3953 | arg1Of | and,the |
| R1051 | T3955 | T3957 | arg1Of | and,of |
| R1053 | T3956 | T3955 | arg2Of | function,and |
| R1054 | T3959 | T3957 | arg2Of | cytokines,of |
| R1055 | T3959 | T3958 | arg1Of | cytokines,proinflammatory |
| R1057 | T3960 | T3961 | arg1Of | IL-10,binds |
| R1058 | T3961 | T3962 | arg1Of | binds,to |
| R1060 | T3965 | T3964 | arg1Of | receptor,IL-10 |
| R1061 | T3965 | T3966 | arg1Of | receptor,( |
| R1062 | T3967 | T3966 | arg2Of | IL-10R,( |
| R1063 | T3968 | T3966 | arg3Of | ),( |
| R1065 | T3969 | T3962 | arg2Of | complex,to |
| R1066 | T3969 | T3963 | arg1Of | complex,the |
| R1067 | T3969 | T3965 | arg1Of | complex,receptor |
| R1068 | T3969 | T3970 | arg1Of | complex,that |
| R1069 | T3969 | T3971 | arg1Of | complex,is |
| R1070 | T3969 | T3972 | arg2Of | complex,composed |
| R1071 | T3972 | T3971 | arg2Of | composed,is |
| R1072 | T3972 | T3973 | arg1Of | composed,of |
| R1076 | T3975 | T3973 | arg2Of | subunits,of |
| R1077 | T3975 | T3974 | arg1Of | subunits,two |
| R1078 | T3975 | T3976 | arg1Of | subunits,"," |
| R1094 | T3987 | T3976 | arg2Of | and,"," |
bionlp-st-ge-2016-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3458 | 328-341 | Antecedent | denotes | type 2 IL-10R |
| T3457 | 276-289 | Antecedent | denotes | type 1 IL-10R |
| T3456 | 225-237 | Anaphor | denotes | two subunits |
| T3461 | 4315-4320 | Antecedent | denotes | IL-17 |
| T3460 | 4286-4302 | Antecedent | denotes | interferon gamma |
| T3459 | 4248-4277 | Anaphor | denotes | proinflammatory Th1 cytokines |
| R942 | T3456 | T3457 | boundBy | two subunits,type 1 IL-10R |
| R943 | T3456 | T3458 | boundBy | two subunits,type 2 IL-10R |
| R944 | T3459 | T3460 | boundBy | proinflammatory Th1 cytokines,interferon gamma |
| R945 | T3459 | T3461 | boundBy | proinflammatory Th1 cytokines,IL-17 |
bionlp-st-ge-2016-test-proteins
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3520 | 4343-4346 | Protein | denotes | CD4 |
| T3519 | 4315-4320 | Protein | denotes | IL-17 |
| T3518 | 4303-4310 | Protein | denotes | (IFN)-γ |
| T3517 | 4286-4302 | Protein | denotes | interferon gamma |
| T3516 | 4216-4220 | Protein | denotes | CD11 |
| T3515 | 4207-4211 | Protein | denotes | CD69 |
| T3514 | 4026-4029 | Protein | denotes | CD4 |
| T3513 | 3954-3958 | Protein | denotes | CD86 |
| T3512 | 3945-3949 | Protein | denotes | CD80 |
| T3511 | 3931-3935 | Protein | denotes | CD28 |
| T3510 | 3799-3812 | Protein | denotes | HLA-DRB1*0401 |
| T3509 | 3781-3794 | Protein | denotes | HLA-DRB1*0404 |
| T3486 | 1184-1188 | Protein | denotes | IL-6 |
| T3485 | 1082-1087 | Protein | denotes | IL-10 |
| T3484 | 1048-1053 | Protein | denotes | STAT3 |
| T3483 | 1011-1016 | Protein | denotes | STAT3 |
| T3482 | 937-941 | Protein | denotes | IL-6 |
| T3481 | 901-906 | Protein | denotes | IL-10 |
| T3480 | 869-874 | Protein | denotes | STAT3 |
| T3479 | 736-741 | Protein | denotes | STAT3 |
| T3478 | 726-731 | Protein | denotes | STAT1 |
| T3477 | 693-698 | Protein | denotes | STAT1 |
| T3476 | 631-688 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
| T3475 | 539-544 | Protein | denotes | IL-10 |
| T3474 | 506-519 | Protein | denotes | type 2 IL-10R |
| T3473 | 494-501 | Protein | denotes | IL-10R1 |
| T3472 | 447-451 | Protein | denotes | Tyk2 |
| T3471 | 438-442 | Protein | denotes | Jak1 |
| T3470 | 376-382 | Protein | denotes | IL-10R |
| T3469 | 366-371 | Protein | denotes | IL-10 |
| T3468 | 328-341 | Protein | denotes | type 2 IL-10R |
| T3467 | 291-298 | Protein | denotes | IL-10R1 |
| T3466 | 276-289 | Protein | denotes | type 1 IL-10R |
| T3465 | 189-195 | Protein | denotes | IL-10R |
| T3464 | 173-187 | Protein | denotes | IL-10 receptor |
| T3463 | 154-159 | Protein | denotes | IL-10 |
| T3462 | 14-18 | Protein | denotes | L-10 |
| T3536 | 5300-5303 | Protein | denotes | CD4 |
| T3535 | 5264-5269 | Protein | denotes | SOCS3 |
| T3534 | 5254-5259 | Protein | denotes | SOCS1 |
| T3533 | 5225-5230 | Protein | denotes | IL-10 |
| T3532 | 5200-5205 | Protein | denotes | STAT3 |
| T3531 | 5190-5195 | Protein | denotes | STAT1 |
| T3530 | 5166-5171 | Protein | denotes | IL-10 |
| T3529 | 5128-5132 | Protein | denotes | CD28 |
| T3528 | 5108-5113 | Protein | denotes | IFN-γ |
| T3527 | 5028-5031 | Protein | denotes | CD4 |
| T3526 | 4886-4890 | Protein | denotes | CD28 |
| T3525 | 4797-4802 | Protein | denotes | IL-10 |
| T3524 | 4768-4772 | Protein | denotes | CD86 |
| T3523 | 4759-4763 | Protein | denotes | CD80 |
| T3522 | 4729-4733 | Protein | denotes | CD28 |
| T3521 | 4644-4693 | Protein | denotes | cytotoxic T-cell-associated antigen 4 (CD152)-IgG |
| T3508 | 3628-3632 | Protein | denotes | CD28 |
| T3507 | 3551-3554 | Protein | denotes | CD4 |
| T3506 | 3496-3544 | Protein | denotes | granulocyte–macrophage colony-stimulating factor |
| T3505 | 3486-3490 | Protein | denotes | IL-1 |
| T3504 | 3479-3484 | Protein | denotes | TNF-α |
| T3503 | 3401-3408 | Protein | denotes | IL-10R1 |
| T3502 | 3339-3343 | Protein | denotes | IL-1 |
| T3501 | 3329-3334 | Protein | denotes | TNF-α |
| T3500 | 3227-3232 | Protein | denotes | IL-10 |
| T3499 | 3132-3137 | Protein | denotes | IL-10 |
| T3498 | 2834-2839 | Protein | denotes | IL-10 |
| T3497 | 2465-2485 | Protein | denotes | pleiotropic cytokine |
| T3496 | 2455-2459 | Protein | denotes | IL-6 |
| T3495 | 2167-2171 | Protein | denotes | IL-1 |
| T3494 | 2156-2161 | Protein | denotes | TNF-α |
| T3493 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T3492 | 1721-1726 | Protein | denotes | IL-10 |
| T3491 | 1692-1696 | Protein | denotes | IL-6 |
| T3490 | 1664-1669 | Protein | denotes | STAT3 |
| T3489 | 1633-1637 | Protein | denotes | IL-6 |
| T3488 | 1623-1628 | Protein | denotes | IL-10 |
| T3487 | 1562-1567 | Protein | denotes | SOCS3 |
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3701 | 1633-1637 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
| T3700 | 1184-1188 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
| T3699 | 937-941 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
| T3698 | 5200-5205 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
| T3697 | 1664-1669 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
| T3696 | 1048-1053 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
| T3695 | 1011-1016 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
| T3694 | 869-874 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
| T3693 | 736-741 | http://www.uniprot.org/uniprot/P40763 | denotes | STAT3 |
| T3692 | 535-541 | http://www.uniprot.org/uniprot/P60568 | denotes | 2]. IL |
| T3691 | 511-515 | http://www.uniprot.org/uniprot/P60568 | denotes | 2 IL |
| T3690 | 333-337 | http://www.uniprot.org/uniprot/P60568 | denotes | 2 IL |
| T3689 | 5225-5230 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3688 | 5166-5171 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3687 | 4797-4802 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3686 | 3227-3232 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3685 | 3132-3137 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3684 | 2834-2839 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3683 | 1721-1726 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3682 | 1623-1628 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3681 | 1082-1087 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3680 | 901-906 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3679 | 539-544 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3678 | 366-371 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3677 | 173-178 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3676 | 154-159 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3675 | 13-18 | http://www.uniprot.org/uniprot/P22301 | denotes | IL-10 |
| T3864 | 5254-5259 | http://www.uniprot.org/uniprot/O15524 | denotes | SOCS1 |
| T3863 | 5120-5123 | http://www.uniprot.org/uniprot/P09693 | denotes | CD3 |
| T3862 | 5120-5123 | http://www.uniprot.org/uniprot/P07766 | denotes | CD3 |
| T3861 | 5120-5123 | http://www.uniprot.org/uniprot/P04234 | denotes | CD3 |
| T3860 | 5120-5123 | http://www.uniprot.org/uniprot/P20963 | denotes | CD3 |
| T3859 | 4315-4320 | http://www.uniprot.org/uniprot/Q16552 | denotes | IL-17 |
| T3858 | 5108-5113 | http://www.uniprot.org/uniprot/P01579 | denotes | IFN-γ |
| T3857 | 4297-4307 | http://www.uniprot.org/uniprot/P01579 | denotes | gamma (IFN |
| T3856 | 4768-4772 | http://www.uniprot.org/uniprot/P42081 | denotes | CD86 |
| T3855 | 3954-3958 | http://www.uniprot.org/uniprot/P42081 | denotes | CD86 |
| T3854 | 4759-4763 | http://www.uniprot.org/uniprot/P33681 | denotes | CD80 |
| T3853 | 3945-3949 | http://www.uniprot.org/uniprot/P33681 | denotes | CD80 |
| T3852 | 5128-5132 | http://www.uniprot.org/uniprot/P10747 | denotes | CD28 |
| T3851 | 4886-4890 | http://www.uniprot.org/uniprot/P10747 | denotes | CD28 |
| T3850 | 4729-4733 | http://www.uniprot.org/uniprot/P10747 | denotes | CD28 |
| T3849 | 3931-3935 | http://www.uniprot.org/uniprot/P10747 | denotes | CD28 |
| T3848 | 3628-3632 | http://www.uniprot.org/uniprot/P10747 | denotes | CD28 |
| T3847 | 5300-5303 | http://www.uniprot.org/uniprot/P01730 | denotes | CD4 |
| T3846 | 5028-5031 | http://www.uniprot.org/uniprot/P01730 | denotes | CD4 |
| T3845 | 4343-4346 | http://www.uniprot.org/uniprot/P01730 | denotes | CD4 |
| T3844 | 4026-4029 | http://www.uniprot.org/uniprot/P01730 | denotes | CD4 |
| T3843 | 3551-3554 | http://www.uniprot.org/uniprot/P01730 | denotes | CD4 |
| T3842 | 3479-3482 | http://www.uniprot.org/uniprot/P01375 | denotes | TNF |
| T3841 | 3329-3332 | http://www.uniprot.org/uniprot/P01375 | denotes | TNF |
| T3840 | 2156-2159 | http://www.uniprot.org/uniprot/P01375 | denotes | TNF |
| T3839 | 3329-3334 | http://www.uniprot.org/uniprot/P01375 | denotes | TNF-α |
| T3704 | 2149-2159 | http://www.uniprot.org/uniprot/P01375 | denotes | alpha (TNF |
| T3703 | 2455-2459 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
| T3702 | 1692-1696 | http://www.uniprot.org/uniprot/P05231 | denotes | IL-6 |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2429 | 5289-5294 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T2428 | 3425-3439 | http://purl.obolibrary.org/obo/UBERON_0001090 | denotes | synovial fluid |
| T2427 | 2903-2909 | http://purl.obolibrary.org/obo/UBERON_0000479 | denotes | tissue |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3310 | 4850-4867 | http://purl.obolibrary.org/obo/GO_0034097 | denotes | cytokine response |
| T3309 | 4843-4858 | http://purl.obolibrary.org/obo/GO_0002369 | denotes | T-cell cytokine |
| T3308 | 4605-4620 | http://purl.obolibrary.org/obo/GO_0001775 | denotes | cell activation |
| T3307 | 4603-4620 | http://purl.obolibrary.org/obo/GO_1903905 | denotes | T-cell activation |
| T3306 | 4603-4620 | http://purl.obolibrary.org/obo/GO_0050863 | denotes | T-cell activation |
| T3305 | 4603-4620 | http://purl.obolibrary.org/obo/GO_0050798 | denotes | T-cell activation |
| T3303 | 4603-4620 | http://purl.obolibrary.org/obo/GO_0051132 | denotes | T-cell activation |
| T3302 | 4372-4389 | http://purl.obolibrary.org/obo/GO_0002368 | denotes | B-cell production |
| T3301 | 4100-4125 | http://purl.obolibrary.org/obo/GO_0042116 | denotes | activation of macrophages |
| T3300 | 3185-3197 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
| T3299 | 2695-2715 | http://purl.obolibrary.org/obo/GO_0030154 | denotes | cell differentiation |
| T3298 | 2614-2629 | http://purl.obolibrary.org/obo/GO_0048469 | denotes | cell maturation |
| T3297 | 2612-2629 | http://purl.obolibrary.org/obo/GO_0002344 | denotes | B-cell maturation |
| T3296 | 2512-2533 | http://purl.obolibrary.org/obo/GO_0072537 | denotes | activated fibroblasts |
| T3295 | 2373-2379 | http://purl.obolibrary.org/obo/GO_0040007 | denotes | growth |
| T3294 | 2133-2141 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
| T3293 | 2133-2141 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
| T3292 | 2133-2141 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
| T3291 | 2133-2141 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
| T3290 | 3178-3197 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signal transduction |
| T3289 | 1489-1507 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathways |
| T3288 | 1480-1507 | http://purl.obolibrary.org/obo/GO_0019221 | denotes | cytokine signaling pathways |
| T3287 | 1342-1359 | http://purl.obolibrary.org/obo/GO_0033673 | denotes | kinase inhibitors |
| T3286 | 1212-1221 | http://purl.obolibrary.org/obo/GO_0097194 | denotes | apoptosis |
| T3285 | 1212-1221 | http://purl.obolibrary.org/obo/GO_0006915 | denotes | apoptosis |
| T3284 | 4891-4900 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T3283 | 4172-4181 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T3282 | 3656-3665 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T3281 | 3233-3242 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T3280 | 3178-3184 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signal |
| T3273 | 709-724 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
| T3272 | 562-577 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
| T3271 | 553-592 | http://purl.obolibrary.org/obo/GO_0050731 | denotes | tyrosine phosphorylation and activation |
| T3270 | 1338-1341 | http://purl.obolibrary.org/obo/GO_0004713 | denotes | JAK |
| T3269 | 409-412 | http://purl.obolibrary.org/obo/GO_0004713 | denotes | JAK |
| T3268 | 179-191 | http://purl.obolibrary.org/obo/GO_0004896 | denotes | receptor (IL |
| T3267 | 513-519 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3266 | 376-382 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3265 | 335-341 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3264 | 283-289 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3263 | 189-195 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3262 | 173-187 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10 receptor |
| T3261 | 3213-3225 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T3260 | 2242-2254 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T3259 | 51-73 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory responses |
| T3304 | 4603-4620 | http://purl.obolibrary.org/obo/GO_0042110 | denotes | T-cell activation |
| T3279 | 631-637 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signal |
| T3278 | 840-853 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
| T3277 | 666-679 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
| T3276 | 607-622 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcriptional |
| T3275 | 562-592 | http://purl.obolibrary.org/obo/GO_0042327 | denotes | phosphorylation and activation |
| T3274 | 5206-5221 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3597 | 4656-4671 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell-associated |
| T3596 | 4194-4206 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell surface |
| T3595 | 4159-4171 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell surface |
| T3594 | 3374-3386 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | Cell surface |
| T3593 | 1747-1755 | http://purl.obolibrary.org/obo/GO_0016020 | denotes | membrane |
| T3592 | 5307-5312 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3591 | 5035-5040 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3590 | 4990-4995 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3589 | 4845-4849 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3588 | 4656-4660 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3587 | 4605-4609 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3586 | 4374-4378 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3585 | 4194-4198 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3584 | 4159-4163 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3583 | 2695-2699 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3582 | 2651-2655 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3581 | 2614-2618 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3580 | 992-996 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3579 | 813-820 | http://purl.obolibrary.org/obo/GO_0005634 | denotes | nucleus |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3578 | 4792-4799 | http://purl.obolibrary.org/obo/GO_0045519 | denotes | 23]. IL |
| T3577 | 4315-4320 | http://purl.obolibrary.org/obo/GO_0030367 | denotes | IL-17 |
| T3576 | 4286-4302 | http://purl.obolibrary.org/obo/GO_0005133 | denotes | interferon gamma |
| T3575 | 2455-2459 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T3574 | 1692-1696 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T3573 | 1633-1637 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T3572 | 1184-1188 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T3571 | 937-941 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
| T3570 | 1338-1341 | http://purl.obolibrary.org/obo/GO_0004713 | denotes | JAK |
| T3569 | 409-412 | http://purl.obolibrary.org/obo/GO_0004713 | denotes | JAK |
| T3568 | 535-541 | http://purl.obolibrary.org/obo/GO_0005134 | denotes | 2]. IL |
| T3567 | 511-515 | http://purl.obolibrary.org/obo/GO_0005134 | denotes | 2 IL |
| T3566 | 333-337 | http://purl.obolibrary.org/obo/GO_0005134 | denotes | 2 IL |
| T3565 | 3486-3490 | http://purl.obolibrary.org/obo/GO_0005149 | denotes | IL-1 |
| T3564 | 3339-3343 | http://purl.obolibrary.org/obo/GO_0005149 | denotes | IL-1 |
| T3563 | 2167-2171 | http://purl.obolibrary.org/obo/GO_0005149 | denotes | IL-1 |
| T3562 | 281-285 | http://purl.obolibrary.org/obo/GO_0005149 | denotes | 1 IL |
| T3561 | 4748-4755 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T3560 | 258-265 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T3559 | 251-257 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | ligand |
| T3558 | 179-191 | http://purl.obolibrary.org/obo/GO_0004896 | denotes | receptor (IL |
| T3557 | 513-519 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3556 | 376-382 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3555 | 335-341 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3554 | 283-289 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3553 | 189-195 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10R |
| T3552 | 173-187 | http://purl.obolibrary.org/obo/GO_0004920 | denotes | IL-10 receptor |
| T3551 | 5225-5230 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3550 | 5166-5171 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3549 | 4797-4802 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3548 | 3227-3232 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3547 | 3132-3137 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3546 | 2834-2839 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3545 | 1721-1726 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3544 | 1623-1628 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3543 | 1082-1087 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3542 | 901-906 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3541 | 539-544 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3540 | 366-371 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3539 | 173-178 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3538 | 154-159 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
| T3537 | 13-18 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3258 | 4997-5330 | Sentence | denotes | To elucidate the resistance of CD4+ T cells to this direct inhibition in RA, we investigated the production of IFN-γ after CD3 and CD28 costimulation in the presence of IL-10, the induction of STAT1 and STAT3 phosphorylation by IL-10, and the expression of SOCS1 and SOCS3 mRNA in peripheral blood (PB) CD4+ T cells from RA patients. |
| T3257 | 4797-4996 | Sentence | denotes | IL-10 efficiently blocks the antigen-specific T-cell cytokine response by inhibiting the CD28 signaling pathway [24], as well as indirectly by downregulating the function of antigen-presenting cells. |
| T3256 | 4476-4796 | Sentence | denotes | Their obligatory role in RA synovitis was recently proved by successful treatment of active disease by selective inhibition of T-cell activation with fusion protein of cytotoxic T-cell-associated antigen 4 (CD152)-IgG, which can block the engagement of CD28 on T cells by binding to CD80 and CD86 with high avidity [23]. |
| T3255 | 4330-4475 | Sentence | denotes | In addition, CD4+ T cells could stimulate B-cell production of autoantibodies such as rheumatoid factor and osteoclast-mediated bone destruction. |
| T3254 | 3988-4329 | Sentence | denotes | The continuing emergence of activated CD4+ T cells, even though few in number, may be crucial in sustaining the activation of macrophages and synovial fibroblasts through cell surface signaling by means of cell surface CD69 and CD11, as well as the release of proinflammatory Th1 cytokines such as interferon gamma (IFN)-γ and IL-17 [21,22]. |
| T3253 | 3674-3987 | Sentence | denotes | The significance of this autoimmune process has been supported by the linkage of the MHC class II antigens HLA-DRB1*0404 and HLA-DRB1*0401 with disease susceptibility and severity [16,17], and by the high-level expression of MHC class II molecules and both CD28 ligands, CD80 and CD86, in the inflamed ST [18-20]. |
| T3252 | 3551-3673 | Sentence | denotes | CD4+ T cells may be activated by arthritogenic antigens, in conjunction with CD28-mediated costimulatory signaling, in RA. |
| T3251 | 3374-3550 | Sentence | denotes | Cell surface expression of IL-10R1 is decreased in synovial fluid dendritic cells due to the presence of TNF-α, IL-1, and granulocyte–macrophage colony-stimulating factor [15]. |
| T3250 | 3227-3373 | Sentence | denotes | IL-10 signaling is impaired in macrophages upon chronic exposure to proinflammatory cytokines such as TNF-α and IL-1 and immune complexes [13,14]. |
| T3249 | 3087-3226 | Sentence | denotes | In addition, the anti-inflammatory action of IL-10 appears to be modulated at the level of signal transduction during chronic inflammation. |
| T3248 | 2834-3086 | Sentence | denotes | IL-10, produced by macrophages and partly by T cells in the synovial tissue (ST), is best known as a negative regulator for macrophage and Th1 cells, but the expression level is insufficient to counterbalance the cascade of proinflammatory events [12]. |
| T3247 | 2722-2833 | Sentence | denotes | However, anti-inflammatory cytokines and cytokine inhibitors are also present in large quantities in RA joints. |
| T3238 | 704-854 | Sentence | denotes | Upon phosphorylation, STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription. |
| T3237 | 539-703 | Sentence | denotes | IL-10 induces tyrosine phosphorylation and activation of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 and STAT1 [3]. |
| T3236 | 347-538 | Sentence | denotes | The interaction of IL-10 and IL-10R engages the Janus kinase (JAK) family tyrosine kinases Jak1 and Tyk2, which are constitutively associated with IL-10R1 and type 2 IL-10R, respectively [2]. |
| T3235 | 154-346 | Sentence | denotes | IL-10 binds to the IL-10 receptor (IL-10R) complex that is composed of two subunits, the primary ligand-binding component type 1 IL-10R (IL-10R1) and the accessory component type 2 IL-10R [1]. |
| T3234 | 13-153 | Sentence | denotes | IL-10 is a key cytokine in regulating inflammatory responses, mainly by inhibiting the production and function of proinflammatory cytokines. |
| T3246 | 2455-2721 | Sentence | denotes | IL-6 is a pleiotropic cytokine produced substantially by activated fibroblasts, and its proinflammatory actions include simulating the acute-phase response, B-cell maturation into plasma cells, T-cell functions, and hematopoietic precursor cell differentiation [11]. |
| T3245 | 2127-2454 | Sentence | denotes | Tumor necrosis factor alpha (TNF-α) and IL-1, two major macrophage products, are crucial in the process of chronic inflammation and joint destruction, and they give rise to effector components, including other inflammatory cytokines, chemokines, growth factors, matrix proteases, nitric oxide, and reactive oxygen species [10]. |
| T3244 | 1973-2126 | Sentence | denotes | Numerous cytokines are overproduced in the inflamed joint, and macrophages and synovial fibroblasts are an important source of proinflammatory cytokines. |
| T3243 | 1734-1972 | Sentence | denotes | The synovial membrane of rheumatoid arthritis (RA) is characterized by an infiltrate of a variety of inflammatory cells, such as lymphocytes, macrophages, and dendritic cells, together with proliferation of synovial fibroblast-like cells. |
| T3242 | 1533-1733 | Sentence | denotes | Recent studies indicate that SOCS3 plays a key role in regulating the divergent action of IL-10 and IL-6, by specifically blocking STAT3 activation induced by IL-6 but not that induced by IL-10 [8,9]. |
| T3241 | 1238-1532 | Sentence | denotes | The suppressor of cytokine signaling (SOCS) proteins have been identified as a family of endogenous JAK kinase inhibitors that can act in classic feedback inhibition loops, but their roles as the mediators of crosstalk inhibition by opposing cytokine signaling pathways have been clarified [7]. |
| T3240 | 981-1237 | Sentence | denotes | Studies of cell-type-specific STAT3-deficient mice have shown that STAT3 activation is essential for IL-10-mediated anti-inflammatory reactions in macrophages and neutrophils [5], but is responsible for IL-6-mediated prevention of apoptosis in T cells [6]. |
| T3239 | 855-980 | Sentence | denotes | Intriguingly, STAT3 is indispensable for both IL-10-derived anti-inflammatory and IL-6-derived proinflammatory responses [4]. |
| T10 | 0-12 | Sentence | denotes | Introduction |
| T11 | 13-153 | Sentence | denotes | IL-10 is a key cytokine in regulating inflammatory responses, mainly by inhibiting the production and function of proinflammatory cytokines. |
| T12 | 154-346 | Sentence | denotes | IL-10 binds to the IL-10 receptor (IL-10R) complex that is composed of two subunits, the primary ligand-binding component type 1 IL-10R (IL-10R1) and the accessory component type 2 IL-10R [1]. |
| T13 | 347-538 | Sentence | denotes | The interaction of IL-10 and IL-10R engages the Janus kinase (JAK) family tyrosine kinases Jak1 and Tyk2, which are constitutively associated with IL-10R1 and type 2 IL-10R, respectively [2]. |
| T14 | 539-703 | Sentence | denotes | IL-10 induces tyrosine phosphorylation and activation of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 and STAT1 [3]. |
| T15 | 704-854 | Sentence | denotes | Upon phosphorylation, STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription. |
| T16 | 855-980 | Sentence | denotes | Intriguingly, STAT3 is indispensable for both IL-10-derived anti-inflammatory and IL-6-derived proinflammatory responses [4]. |
| T17 | 981-1237 | Sentence | denotes | Studies of cell-type-specific STAT3-deficient mice have shown that STAT3 activation is essential for IL-10-mediated anti-inflammatory reactions in macrophages and neutrophils [5], but is responsible for IL-6-mediated prevention of apoptosis in T cells [6]. |
| T18 | 1238-1532 | Sentence | denotes | The suppressor of cytokine signaling (SOCS) proteins have been identified as a family of endogenous JAK kinase inhibitors that can act in classic feedback inhibition loops, but their roles as the mediators of crosstalk inhibition by opposing cytokine signaling pathways have been clarified [7]. |
| T19 | 1533-1733 | Sentence | denotes | Recent studies indicate that SOCS3 plays a key role in regulating the divergent action of IL-10 and IL-6, by specifically blocking STAT3 activation induced by IL-6 but not that induced by IL-10 [8,9]. |
| T20 | 1734-1972 | Sentence | denotes | The synovial membrane of rheumatoid arthritis (RA) is characterized by an infiltrate of a variety of inflammatory cells, such as lymphocytes, macrophages, and dendritic cells, together with proliferation of synovial fibroblast-like cells. |
| T21 | 1973-2126 | Sentence | denotes | Numerous cytokines are overproduced in the inflamed joint, and macrophages and synovial fibroblasts are an important source of proinflammatory cytokines. |
| T22 | 2127-2454 | Sentence | denotes | Tumor necrosis factor alpha (TNF-α) and IL-1, two major macrophage products, are crucial in the process of chronic inflammation and joint destruction, and they give rise to effector components, including other inflammatory cytokines, chemokines, growth factors, matrix proteases, nitric oxide, and reactive oxygen species [10]. |
| T23 | 2455-2721 | Sentence | denotes | IL-6 is a pleiotropic cytokine produced substantially by activated fibroblasts, and its proinflammatory actions include simulating the acute-phase response, B-cell maturation into plasma cells, T-cell functions, and hematopoietic precursor cell differentiation [11]. |
| T24 | 2722-2833 | Sentence | denotes | However, anti-inflammatory cytokines and cytokine inhibitors are also present in large quantities in RA joints. |
| T25 | 2834-3086 | Sentence | denotes | IL-10, produced by macrophages and partly by T cells in the synovial tissue (ST), is best known as a negative regulator for macrophage and Th1 cells, but the expression level is insufficient to counterbalance the cascade of proinflammatory events [12]. |
| T26 | 3087-3226 | Sentence | denotes | In addition, the anti-inflammatory action of IL-10 appears to be modulated at the level of signal transduction during chronic inflammation. |
| T27 | 3227-3373 | Sentence | denotes | IL-10 signaling is impaired in macrophages upon chronic exposure to proinflammatory cytokines such as TNF-α and IL-1 and immune complexes [13,14]. |
| T28 | 3374-3550 | Sentence | denotes | Cell surface expression of IL-10R1 is decreased in synovial fluid dendritic cells due to the presence of TNF-α, IL-1, and granulocyte–macrophage colony-stimulating factor [15]. |
| T29 | 3551-3673 | Sentence | denotes | CD4+ T cells may be activated by arthritogenic antigens, in conjunction with CD28-mediated costimulatory signaling, in RA. |
| T30 | 3674-3987 | Sentence | denotes | The significance of this autoimmune process has been supported by the linkage of the MHC class II antigens HLA-DRB1*0404 and HLA-DRB1*0401 with disease susceptibility and severity [16,17], and by the high-level expression of MHC class II molecules and both CD28 ligands, CD80 and CD86, in the inflamed ST [18-20]. |
| T31 | 3988-4329 | Sentence | denotes | The continuing emergence of activated CD4+ T cells, even though few in number, may be crucial in sustaining the activation of macrophages and synovial fibroblasts through cell surface signaling by means of cell surface CD69 and CD11, as well as the release of proinflammatory Th1 cytokines such as interferon gamma (IFN)-γ and IL-17 [21,22]. |
| T32 | 4330-4475 | Sentence | denotes | In addition, CD4+ T cells could stimulate B-cell production of autoantibodies such as rheumatoid factor and osteoclast-mediated bone destruction. |
| T33 | 4476-4796 | Sentence | denotes | Their obligatory role in RA synovitis was recently proved by successful treatment of active disease by selective inhibition of T-cell activation with fusion protein of cytotoxic T-cell-associated antigen 4 (CD152)-IgG, which can block the engagement of CD28 on T cells by binding to CD80 and CD86 with high avidity [23]. |
| T34 | 4797-4996 | Sentence | denotes | IL-10 efficiently blocks the antigen-specific T-cell cytokine response by inhibiting the CD28 signaling pathway [24], as well as indirectly by downregulating the function of antigen-presenting cells. |
| T35 | 4997-5330 | Sentence | denotes | To elucidate the resistance of CD4+ T cells to this direct inhibition in RA, we investigated the production of IFN-γ after CD3 and CD28 costimulation in the presence of IL-10, the induction of STAT1 and STAT3 phosphorylation by IL-10, and the expression of SOCS1 and SOCS3 mRNA in peripheral blood (PB) CD4+ T cells from RA patients. |
ICD10
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3599 | 1770-1779 | http://purl.bioontology.org/ontology/ICD10/M13.9 | denotes | arthritis |
| T3598 | 1759-1779 | http://purl.bioontology.org/ontology/ICD10/M06.9 | denotes | rheumatoid arthritis |
simple1
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3939 | 5300-5303 | Protein | denotes | CD4 |
| T3938 | 5264-5269 | Protein | denotes | SOCS3 |
| T3937 | 5254-5259 | Protein | denotes | SOCS1 |
| T3936 | 5225-5230 | Protein | denotes | IL-10 |
| T3935 | 5200-5205 | Protein | denotes | STAT3 |
| T3934 | 5190-5195 | Protein | denotes | STAT1 |
| T3933 | 5166-5171 | Protein | denotes | IL-10 |
| T3932 | 5128-5132 | Protein | denotes | CD28 |
| T3931 | 5108-5113 | Protein | denotes | IFN-γ |
| T3930 | 5028-5031 | Protein | denotes | CD4 |
| T3929 | 4886-4890 | Protein | denotes | CD28 |
| T3928 | 4797-4802 | Protein | denotes | IL-10 |
| T3927 | 4768-4772 | Protein | denotes | CD86 |
| T3926 | 4759-4763 | Protein | denotes | CD80 |
| T3925 | 4729-4733 | Protein | denotes | CD28 |
| T3924 | 4644-4693 | Protein | denotes | cytotoxic T-cell-associated antigen 4 (CD152)-IgG |
| T3923 | 4343-4346 | Protein | denotes | CD4 |
| T3922 | 4315-4320 | Protein | denotes | IL-17 |
| T3921 | 4303-4310 | Protein | denotes | (IFN)-γ |
| T3920 | 4286-4302 | Protein | denotes | interferon gamma |
| T3919 | 4216-4220 | Protein | denotes | CD11 |
| T3918 | 4207-4211 | Protein | denotes | CD69 |
| T3917 | 4026-4029 | Protein | denotes | CD4 |
| T3916 | 3954-3958 | Protein | denotes | CD86 |
| T3915 | 3945-3949 | Protein | denotes | CD80 |
| T3914 | 3931-3935 | Protein | denotes | CD28 |
| T3913 | 3799-3812 | Protein | denotes | HLA-DRB1*0401 |
| T3912 | 3781-3794 | Protein | denotes | HLA-DRB1*0404 |
| T3911 | 3628-3632 | Protein | denotes | CD28 |
| T3910 | 3551-3554 | Protein | denotes | CD4 |
| T3909 | 3496-3544 | Protein | denotes | granulocyte–macrophage colony-stimulating factor |
| T3908 | 3486-3490 | Protein | denotes | IL-1 |
| T3907 | 3479-3484 | Protein | denotes | TNF-α |
| T3906 | 3401-3408 | Protein | denotes | IL-10R1 |
| T3905 | 3339-3343 | Protein | denotes | IL-1 |
| T3904 | 3329-3334 | Protein | denotes | TNF-α |
| T3903 | 3227-3232 | Protein | denotes | IL-10 |
| T3902 | 3132-3137 | Protein | denotes | IL-10 |
| T3901 | 2834-2839 | Protein | denotes | IL-10 |
| T3900 | 2465-2485 | Protein | denotes | pleiotropic cytokine |
| T3899 | 2455-2459 | Protein | denotes | IL-6 |
| T3898 | 2167-2171 | Protein | denotes | IL-1 |
| T3897 | 2156-2161 | Protein | denotes | TNF-α |
| T3896 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T3895 | 1721-1726 | Protein | denotes | IL-10 |
| T3894 | 1692-1696 | Protein | denotes | IL-6 |
| T3893 | 1664-1669 | Protein | denotes | STAT3 |
| T3892 | 1633-1637 | Protein | denotes | IL-6 |
| T3891 | 1623-1628 | Protein | denotes | IL-10 |
| T3890 | 1562-1567 | Protein | denotes | SOCS3 |
| T3889 | 1184-1188 | Protein | denotes | IL-6 |
| T3888 | 1082-1087 | Protein | denotes | IL-10 |
| T3887 | 1048-1053 | Protein | denotes | STAT3 |
| T3886 | 1011-1016 | Protein | denotes | STAT3 |
| T3885 | 937-941 | Protein | denotes | IL-6 |
| T3884 | 901-906 | Protein | denotes | IL-10 |
| T3883 | 869-874 | Protein | denotes | STAT3 |
| T3882 | 736-741 | Protein | denotes | STAT3 |
| T3881 | 726-731 | Protein | denotes | STAT1 |
| T3880 | 693-698 | Protein | denotes | STAT1 |
| T3879 | 631-688 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
| T3878 | 539-544 | Protein | denotes | IL-10 |
| T3877 | 506-519 | Protein | denotes | type 2 IL-10R |
| T3876 | 494-501 | Protein | denotes | IL-10R1 |
| T3875 | 447-451 | Protein | denotes | Tyk2 |
| T3874 | 438-442 | Protein | denotes | Jak1 |
| T3873 | 376-382 | Protein | denotes | IL-10R |
| T3872 | 366-371 | Protein | denotes | IL-10 |
| T3871 | 328-341 | Protein | denotes | type 2 IL-10R |
| T3870 | 291-298 | Protein | denotes | IL-10R1 |
| T3869 | 276-289 | Protein | denotes | type 1 IL-10R |
| T3868 | 189-195 | Protein | denotes | IL-10R |
| T3867 | 173-187 | Protein | denotes | IL-10 receptor |
| T3866 | 154-159 | Protein | denotes | IL-10 |
| T3865 | 14-18 | Protein | denotes | L-10 |
BioNLP16_DUT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T6472 | 5240-5250 | Gene_expression | denotes | expression |
| T6471 | 4715-4725 | Binding | denotes | engagement |
| T6470 | 4748-4755 | Binding | denotes | binding |
| T6469 | 4237-4244 | Localization | denotes | release |
| T6468 | 3412-3421 | Negative_regulation | denotes | decreased |
| T6467 | 3387-3397 | Gene_expression | denotes | expression |
| T6466 | 2841-2849 | Gene_expression | denotes | produced |
| T6465 | 2486-2494 | Gene_expression | denotes | produced |
| T6464 | 1710-1717 | Positive_regulation | denotes | induced |
| T6463 | 1655-1663 | Negative_regulation | denotes | blocking |
| T6462 | 1681-1688 | Positive_regulation | denotes | induced |
| T6461 | 1670-1680 | Positive_regulation | denotes | activation |
| T6460 | 1054-1064 | Positive_regulation | denotes | activation |
| T6459 | 1017-1026 | Negative_regulation | denotes | deficient |
| T6458 | 792-803 | Localization | denotes | translocate |
| T6457 | 709-724 | Phosphorylation | denotes | phosphorylation |
| T6456 | 562-577 | Phosphorylation | denotes | phosphorylation |
| T6455 | 545-552 | Positive_regulation | denotes | induces |
| T6454 | 582-592 | Positive_regulation | denotes | activation |
| T6453 | 478-488 | Binding | denotes | associated |
| T6452 | 351-362 | Binding | denotes | interaction |
| T6451 | 383-390 | Binding | denotes | engages |
| T6450 | 160-165 | Binding | denotes | binds |
| T6449 | 5300-5303 | Protein | denotes | CD4 |
| T6448 | 5264-5269 | Protein | denotes | SOCS3 |
| T6447 | 5254-5259 | Protein | denotes | SOCS1 |
| T6446 | 5225-5230 | Protein | denotes | IL-10 |
| T6445 | 5200-5205 | Protein | denotes | STAT3 |
| T6444 | 5190-5195 | Protein | denotes | STAT1 |
| T6443 | 5166-5171 | Protein | denotes | IL-10 |
| T6442 | 5128-5132 | Protein | denotes | CD28 |
| T6441 | 5108-5113 | Protein | denotes | IFN-γ |
| T6440 | 5028-5031 | Protein | denotes | CD4 |
| T6439 | 4886-4890 | Protein | denotes | CD28 |
| T6438 | 4797-4802 | Protein | denotes | IL-10 |
| T6437 | 4768-4772 | Protein | denotes | CD86 |
| T6436 | 4759-4763 | Protein | denotes | CD80 |
| T6435 | 4729-4733 | Protein | denotes | CD28 |
| T6434 | 4644-4693 | Protein | denotes | cytotoxic T-cell-associated antigen 4 (CD152)-IgG |
| T6433 | 4343-4346 | Protein | denotes | CD4 |
| T6432 | 4315-4320 | Protein | denotes | IL-17 |
| T6431 | 4303-4310 | Protein | denotes | (IFN)-γ |
| T6430 | 4286-4302 | Protein | denotes | interferon gamma |
| T6429 | 4216-4220 | Protein | denotes | CD11 |
| T6428 | 4207-4211 | Protein | denotes | CD69 |
| T6427 | 4026-4029 | Protein | denotes | CD4 |
| T6426 | 3954-3958 | Protein | denotes | CD86 |
| T6425 | 3945-3949 | Protein | denotes | CD80 |
| T6424 | 3931-3935 | Protein | denotes | CD28 |
| T6423 | 3799-3812 | Protein | denotes | HLA-DRB1*0401 |
| T6422 | 3781-3794 | Protein | denotes | HLA-DRB1*0404 |
| T6421 | 3628-3632 | Protein | denotes | CD28 |
| T6420 | 3551-3554 | Protein | denotes | CD4 |
| T6419 | 3496-3544 | Protein | denotes | granulocyte–macrophage colony-stimulating factor |
| T6418 | 3486-3490 | Protein | denotes | IL-1 |
| T6417 | 3479-3484 | Protein | denotes | TNF-α |
| T6416 | 3401-3408 | Protein | denotes | IL-10R1 |
| T6415 | 3339-3343 | Protein | denotes | IL-1 |
| T6414 | 3329-3334 | Protein | denotes | TNF-α |
| T6413 | 3227-3232 | Protein | denotes | IL-10 |
| T6412 | 3132-3137 | Protein | denotes | IL-10 |
| T6411 | 2834-2839 | Protein | denotes | IL-10 |
| T6410 | 2465-2485 | Protein | denotes | pleiotropic cytokine |
| T6409 | 2455-2459 | Protein | denotes | IL-6 |
| T6408 | 2167-2171 | Protein | denotes | IL-1 |
| T6407 | 2156-2161 | Protein | denotes | TNF-α |
| T6406 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T6405 | 1721-1726 | Protein | denotes | IL-10 |
| T6404 | 1692-1696 | Protein | denotes | IL-6 |
| T6403 | 1664-1669 | Protein | denotes | STAT3 |
| T6402 | 1633-1637 | Protein | denotes | IL-6 |
| T6401 | 1623-1628 | Protein | denotes | IL-10 |
| T6400 | 1562-1567 | Protein | denotes | SOCS3 |
| T6399 | 1184-1188 | Protein | denotes | IL-6 |
| T6398 | 1082-1087 | Protein | denotes | IL-10 |
| T6397 | 1048-1053 | Protein | denotes | STAT3 |
| T6396 | 1011-1016 | Protein | denotes | STAT3 |
| T6395 | 937-941 | Protein | denotes | IL-6 |
| T6394 | 901-906 | Protein | denotes | IL-10 |
| T6393 | 869-874 | Protein | denotes | STAT3 |
| T6392 | 736-741 | Protein | denotes | STAT3 |
| T6391 | 726-731 | Protein | denotes | STAT1 |
| T6390 | 693-698 | Protein | denotes | STAT1 |
| T6389 | 631-688 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
| T6388 | 539-544 | Protein | denotes | IL-10 |
| T6387 | 376-382 | Protein | denotes | IL-10R |
| T6386 | 366-371 | Protein | denotes | IL-10 |
| T6385 | 506-519 | Protein | denotes | type 2 IL-10R |
| T6384 | 494-501 | Protein | denotes | IL-10R1 |
| T6383 | 447-451 | Protein | denotes | Tyk2 |
| T6382 | 438-442 | Protein | denotes | Jak1 |
| T6381 | 328-341 | Protein | denotes | type 2 IL-10R |
| T6380 | 291-298 | Protein | denotes | IL-10R1 |
| T6379 | 276-289 | Protein | denotes | type 1 IL-10R |
| T6378 | 189-195 | Protein | denotes | IL-10R |
| T6377 | 173-187 | Protein | denotes | IL-10 receptor |
| T6376 | 154-159 | Protein | denotes | IL-10 |
| T6375 | 14-18 | Protein | denotes | L-10 |
| T6475 | 5094-5104 | Gene_expression | denotes | production |
| T6474 | 5206-5221 | Phosphorylation | denotes | phosphorylation |
| T6473 | 5177-5186 | Positive_regulation | denotes | induction |
| R3137 | T6376 | T6450 | themeOf | IL-10,binds |
| R3138 | T6376 | T6450 | themeOf | IL-10,binds |
| R3139 | T6377 | T6450 | themeOf | IL-10 receptor,binds |
| R3140 | T6378 | T6450 | themeOf | IL-10R,binds |
| R3142 | T6382 | T6451 | themeOf | Jak1,engages |
| R3143 | T6382 | T6453 | themeOf | Jak1,associated |
| R3145 | T6383 | T6451 | themeOf | Tyk2,engages |
| R3146 | T6383 | T6453 | themeOf | Tyk2,associated |
| R3148 | T6384 | T6453 | themeOf | IL-10R1,associated |
| R3149 | T6409 | T6465 | themeOf | IL-6,produced |
| R3150 | T6384 | T6453 | themeOf | IL-10R1,associated |
| R3151 | T6386 | T6452 | themeOf | IL-10,interaction |
| R3152 | T6387 | T6452 | themeOf | IL-10R,interaction |
| R3153 | T6410 | T6465 | themeOf | pleiotropic cytokine,produced |
| R3154 | T6411 | T6466 | themeOf | IL-10,produced |
| R3155 | T6389 | T6456 | themeOf | signal transducer and activator of transcription (STAT) 3,phosphorylation |
| R3156 | T6389 | T6454 | themeOf | signal transducer and activator of transcription (STAT) 3,activation |
| R3157 | T6416 | T6467 | themeOf | IL-10R1,expression |
| R3158 | T6390 | T6456 | themeOf | STAT1,phosphorylation |
| R3159 | T6390 | T6454 | themeOf | STAT1,activation |
| R3160 | T6430 | T6469 | themeOf | interferon gamma,release |
| R3161 | T6391 | T6458 | themeOf | STAT1,translocate |
| R3162 | T6391 | T6457 | themeOf | STAT1,phosphorylation |
| R3163 | T6392 | T6458 | themeOf | STAT3,translocate |
| R3164 | T6396 | T6459 | themeOf | STAT3,deficient |
| R3165 | T6397 | T6460 | themeOf | STAT3,activation |
| R3166 | T6431 | T6469 | themeOf | (IFN)-γ,release |
| R3167 | T6400 | T6464 | themeOf | SOCS3,induced |
| R3168 | T6432 | T6469 | themeOf | IL-17,release |
| R3169 | T6435 | T6471 | themeOf | CD28,engagement |
| R3170 | T6403 | T6461 | themeOf | STAT3,activation |
| R3171 | T6403 | T6462 | themeOf | STAT3,induced |
| R3172 | T6436 | T6470 | themeOf | CD80,binding |
| R3173 | T6437 | T6470 | themeOf | CD86,binding |
| R3174 | T6441 | T6475 | themeOf | IFN-γ,production |
| R3175 | T6444 | T6473 | themeOf | STAT1,induction |
| R3176 | T6444 | T6474 | themeOf | STAT1,phosphorylation |
| R3177 | T6445 | T6473 | themeOf | STAT3,induction |
| R3178 | T6445 | T6474 | themeOf | STAT3,phosphorylation |
| R3179 | T6446 | T6473 | causeOf | IL-10,induction |
| R3180 | T6446 | T6473 | causeOf | IL-10,induction |
| R3181 | T6446 | T6473 | causeOf | IL-10,induction |
| R3182 | T6446 | T6473 | causeOf | IL-10,induction |
| R3183 | T6447 | T6472 | themeOf | SOCS1,expression |
| R3184 | T6448 | T6472 | themeOf | SOCS3,expression |
| R3185 | T6456 | T6455 | themeOf | phosphorylation,induces |
| R3186 | T6456 | T6455 | themeOf | phosphorylation,induces |
| R3187 | T6461 | T6463 | themeOf | activation,blocking |
| R3188 | T6461 | T6462 | themeOf | activation,induced |
| R3189 | T6467 | T6468 | themeOf | expression,decreased |
| R3190 | T6474 | T6473 | themeOf | phosphorylation,induction |
| R3191 | T6474 | T6473 | themeOf | phosphorylation,induction |
BioNLP16_Messiy
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4914 | 5094-5104 | Gene_expression | denotes | production |
| T4913 | 5240-5250 | Gene_expression | denotes | expression |
| T4912 | 5177-5186 | Positive_regulation | denotes | induction |
| T4911 | 5206-5221 | Phosphorylation | denotes | phosphorylation |
| T4910 | 4715-4725 | Binding | denotes | engagement |
| T4909 | 4748-4755 | Binding | denotes | binding |
| T4908 | 3412-3421 | Negative_regulation | denotes | decreased |
| T4907 | 3387-3397 | Gene_expression | denotes | expression |
| T4906 | 2841-2849 | Gene_expression | denotes | produced |
| T4905 | 2486-2494 | Gene_expression | denotes | produced |
| T4904 | 1681-1688 | Positive_regulation | denotes | induced |
| T4903 | 1655-1663 | Negative_regulation | denotes | blocking |
| T4902 | 1670-1680 | Positive_regulation | denotes | activation |
| T4901 | 1710-1717 | Positive_regulation | denotes | induced |
| T4900 | 1068-1077 | Positive_regulation | denotes | essential |
| T4899 | 1054-1064 | Positive_regulation | denotes | activation |
| T4898 | 1017-1026 | Negative_regulation | denotes | deficient |
| T4897 | 1168-1179 | Regulation | denotes | responsible |
| T4896 | 792-803 | Localization | denotes | translocate |
| T4895 | 545-552 | Positive_regulation | denotes | induces |
| T4894 | 562-577 | Phosphorylation | denotes | phosphorylation |
| T4893 | 582-592 | Positive_regulation | denotes | activation |
| T4892 | 478-488 | Binding | denotes | associated |
| T4891 | 383-390 | Binding | denotes | engages |
| T4890 | 351-362 | Binding | denotes | interaction |
| T4889 | 160-165 | Binding | denotes | binds |
| T4888 | 251-265 | Binding | denotes | ligand-binding |
| T4887 | 5300-5303 | Protein | denotes | CD4 |
| T4886 | 5264-5269 | Protein | denotes | SOCS3 |
| T4885 | 5254-5259 | Protein | denotes | SOCS1 |
| T4884 | 5225-5230 | Protein | denotes | IL-10 |
| T4883 | 5200-5205 | Protein | denotes | STAT3 |
| T4882 | 5190-5195 | Protein | denotes | STAT1 |
| T4881 | 5166-5171 | Protein | denotes | IL-10 |
| T4880 | 5128-5132 | Protein | denotes | CD28 |
| T4879 | 5108-5113 | Protein | denotes | IFN-γ |
| T4878 | 5028-5031 | Protein | denotes | CD4 |
| T4877 | 4886-4890 | Protein | denotes | CD28 |
| T4876 | 4797-4802 | Protein | denotes | IL-10 |
| T4875 | 4768-4772 | Protein | denotes | CD86 |
| T4874 | 4759-4763 | Protein | denotes | CD80 |
| T4873 | 4729-4733 | Protein | denotes | CD28 |
| T4872 | 4644-4693 | Protein | denotes | cytotoxic T-cell-associated antigen 4 (CD152)-IgG |
| T4871 | 4343-4346 | Protein | denotes | CD4 |
| T4870 | 4315-4320 | Protein | denotes | IL-17 |
| T4869 | 4303-4310 | Protein | denotes | (IFN)-γ |
| T4868 | 4286-4302 | Protein | denotes | interferon gamma |
| T4867 | 4216-4220 | Protein | denotes | CD11 |
| T4866 | 4207-4211 | Protein | denotes | CD69 |
| T4865 | 4026-4029 | Protein | denotes | CD4 |
| T4864 | 3954-3958 | Protein | denotes | CD86 |
| T4863 | 3945-3949 | Protein | denotes | CD80 |
| T4862 | 3931-3935 | Protein | denotes | CD28 |
| T4861 | 3799-3812 | Protein | denotes | HLA-DRB1*0401 |
| T4860 | 3781-3794 | Protein | denotes | HLA-DRB1*0404 |
| T4859 | 3628-3632 | Protein | denotes | CD28 |
| T4858 | 3551-3554 | Protein | denotes | CD4 |
| T4857 | 3496-3544 | Protein | denotes | granulocyte–macrophage colony-stimulating factor |
| T4856 | 3486-3490 | Protein | denotes | IL-1 |
| T4855 | 3479-3484 | Protein | denotes | TNF-α |
| T4854 | 3401-3408 | Protein | denotes | IL-10R1 |
| T4853 | 3339-3343 | Protein | denotes | IL-1 |
| T4852 | 3329-3334 | Protein | denotes | TNF-α |
| T4851 | 3227-3232 | Protein | denotes | IL-10 |
| T4850 | 3132-3137 | Protein | denotes | IL-10 |
| T4849 | 2834-2839 | Protein | denotes | IL-10 |
| T4848 | 2465-2485 | Protein | denotes | pleiotropic cytokine |
| T4847 | 2455-2459 | Protein | denotes | IL-6 |
| T4846 | 2167-2171 | Protein | denotes | IL-1 |
| T4845 | 2156-2161 | Protein | denotes | TNF-α |
| T4844 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T4843 | 1721-1726 | Protein | denotes | IL-10 |
| T4842 | 1692-1696 | Protein | denotes | IL-6 |
| T4841 | 1664-1669 | Protein | denotes | STAT3 |
| T4840 | 1633-1637 | Protein | denotes | IL-6 |
| T4839 | 1623-1628 | Protein | denotes | IL-10 |
| T4838 | 1562-1567 | Protein | denotes | SOCS3 |
| T4837 | 1184-1188 | Protein | denotes | IL-6 |
| T4836 | 1082-1087 | Protein | denotes | IL-10 |
| T4835 | 1048-1053 | Protein | denotes | STAT3 |
| T4834 | 1011-1016 | Protein | denotes | STAT3 |
| T4833 | 937-941 | Protein | denotes | IL-6 |
| T4832 | 901-906 | Protein | denotes | IL-10 |
| T4831 | 869-874 | Protein | denotes | STAT3 |
| T4830 | 736-741 | Protein | denotes | STAT3 |
| T4829 | 726-731 | Protein | denotes | STAT1 |
| T4828 | 693-698 | Protein | denotes | STAT1 |
| T4827 | 631-688 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
| T4826 | 539-544 | Protein | denotes | IL-10 |
| T4825 | 376-382 | Protein | denotes | IL-10R |
| T4824 | 366-371 | Protein | denotes | IL-10 |
| T4823 | 506-519 | Protein | denotes | type 2 IL-10R |
| T4822 | 494-501 | Protein | denotes | IL-10R1 |
| T4821 | 447-451 | Protein | denotes | Tyk2 |
| T4820 | 438-442 | Protein | denotes | Jak1 |
| T4819 | 328-341 | Protein | denotes | type 2 IL-10R |
| T4818 | 291-298 | Protein | denotes | IL-10R1 |
| T4817 | 276-289 | Protein | denotes | type 1 IL-10R |
| T4816 | 189-195 | Protein | denotes | IL-10R |
| T4815 | 173-187 | Protein | denotes | IL-10 receptor |
| T4814 | 154-159 | Protein | denotes | IL-10 |
| T4813 | 14-18 | Protein | denotes | L-10 |
| R1849 | T4814 | T4889 | themeOf | IL-10,binds |
| R1851 | T4814 | T4889 | themeOf | IL-10,binds |
| R1853 | T4815 | T4889 | themeOf | IL-10 receptor,binds |
| R1854 | T4816 | T4889 | themeOf | IL-10R,binds |
| R1858 | T4818 | T4888 | themeOf | IL-10R1,ligand-binding |
| R1862 | T4820 | T4891 | themeOf | Jak1,engages |
| R1866 | T4821 | T4891 | themeOf | Tyk2,engages |
| R1867 | T4821 | T4892 | themeOf | Tyk2,associated |
| R1869 | T4822 | T4892 | themeOf | IL-10R1,associated |
| R1871 | T4824 | T4890 | themeOf | IL-10,interaction |
| R1872 | T4825 | T4890 | themeOf | IL-10R,interaction |
| R1874 | T4826 | T4895 | causeOf | IL-10,induces |
| R1878 | T4827 | T4894 | themeOf | signal transducer and activator of transcription (STAT) 3,phosphorylation |
| R1880 | T4827 | T4893 | themeOf | signal transducer and activator of transcription (STAT) 3,activation |
| R1881 | T4828 | T4895 | themeOf | STAT1,induces |
| R1882 | T4828 | T4894 | themeOf | STAT1,phosphorylation |
| R1884 | T4828 | T4893 | themeOf | STAT1,activation |
| R1887 | T4829 | T4896 | themeOf | STAT1,translocate |
| R1888 | T4830 | T4896 | themeOf | STAT3,translocate |
| R1892 | T4834 | T4898 | themeOf | STAT3,deficient |
| R1894 | T4835 | T4899 | themeOf | STAT3,activation |
| R1896 | T4838 | T4903 | causeOf | SOCS3,blocking |
| R1899 | T4838 | T4901 | causeOf | SOCS3,induced |
| R1902 | T4841 | T4902 | themeOf | STAT3,activation |
| R1904 | T4841 | T4904 | themeOf | STAT3,induced |
| R1907 | T4842 | T4904 | causeOf | IL-6,induced |
| R1908 | T4842 | T4904 | causeOf | IL-6,induced |
| R1911 | T4843 | T4901 | themeOf | IL-10,induced |
| R1914 | T4847 | T4905 | themeOf | IL-6,produced |
| R1917 | T4848 | T4905 | themeOf | pleiotropic cytokine,produced |
| R1920 | T4849 | T4906 | themeOf | IL-10,produced |
| R1923 | T4854 | T4907 | themeOf | IL-10R1,expression |
| R1932 | T4873 | T4910 | themeOf | CD28,engagement |
| R1934 | T4874 | T4909 | themeOf | CD80,binding |
| R1937 | T4875 | T4909 | themeOf | CD86,binding |
| R1940 | T4879 | T4914 | themeOf | IFN-γ,production |
| R1943 | T4882 | T4912 | themeOf | STAT1,induction |
| R1945 | T4882 | T4911 | themeOf | STAT1,phosphorylation |
| R1948 | T4883 | T4912 | themeOf | STAT3,induction |
| R1951 | T4883 | T4911 | themeOf | STAT3,phosphorylation |
| R1952 | T4884 | T4912 | causeOf | IL-10,induction |
| R1954 | T4884 | T4912 | causeOf | IL-10,induction |
| R1955 | T4884 | T4912 | causeOf | IL-10,induction |
| R1957 | T4884 | T4912 | causeOf | IL-10,induction |
| R1960 | T4885 | T4913 | themeOf | SOCS1,expression |
| R1962 | T4886 | T4913 | themeOf | SOCS3,expression |
| R1968 | T4899 | T4900 | themeOf | activation,essential |
| R1971 | T4899 | T4897 | themeOf | activation,responsible |
| R1973 | T4902 | T4903 | themeOf | activation,blocking |
| R1974 | T4902 | T4904 | themeOf | activation,induced |
| R1977 | T4907 | T4908 | themeOf | expression,decreased |
| R1980 | T4911 | T4912 | themeOf | phosphorylation,induction |
| R1981 | T4911 | T4912 | themeOf | phosphorylation,induction |
DLUT931
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T5934 | 5077-5089 | Positive_regulation | denotes | investigated |
| T5933 | 5240-5250 | Gene_expression | denotes | expression |
| T5932 | 5206-5221 | Phosphorylation | denotes | phosphorylation |
| T5931 | 5177-5186 | Positive_regulation | denotes | induction |
| T5930 | 5133-5146 | Positive_regulation | denotes | costimulation |
| T5929 | 5094-5104 | Gene_expression | denotes | production |
| T5928 | 4871-4881 | Negative_regulation | denotes | inhibiting |
| T5927 | 4705-4710 | Negative_regulation | denotes | block |
| T5926 | 4748-4755 | Binding | denotes | binding |
| T5925 | 4715-4725 | Binding | denotes | engagement |
| T5924 | 3885-3895 | Gene_expression | denotes | expression |
| T5923 | 3412-3421 | Negative_regulation | denotes | decreased |
| T5922 | 3387-3397 | Gene_expression | denotes | expression |
| T5921 | 3152-3161 | Regulation | denotes | modulated |
| T5920 | 2992-3002 | Gene_expression | denotes | expression |
| T5919 | 2841-2849 | Gene_expression | denotes | produced |
| T5918 | 2512-2521 | Positive_regulation | denotes | activated |
| T5917 | 2486-2494 | Gene_expression | denotes | produced |
| T5916 | 1655-1663 | Negative_regulation | denotes | blocking |
| T5915 | 1681-1688 | Positive_regulation | denotes | induced |
| T5914 | 1670-1680 | Positive_regulation | denotes | activation |
| T5913 | 1588-1598 | Regulation | denotes | regulating |
| T5912 | 1088-1096 | Positive_regulation | denotes | mediated |
| T5911 | 1054-1064 | Positive_regulation | denotes | activation |
| T5910 | 1017-1026 | Negative_regulation | denotes | deficient |
| T5909 | 826-834 | Regulation | denotes | modulate |
| T5908 | 792-803 | Localization | denotes | translocate |
| T5907 | 709-724 | Phosphorylation | denotes | phosphorylation |
| T5906 | 545-552 | Positive_regulation | denotes | induces |
| T5905 | 582-592 | Positive_regulation | denotes | activation |
| T5904 | 562-577 | Phosphorylation | denotes | phosphorylation |
| T5903 | 383-390 | Binding | denotes | engages |
| T5902 | 351-362 | Binding | denotes | interaction |
| T5901 | 251-265 | Binding | denotes | ligand-binding |
| T5900 | 160-165 | Binding | denotes | binds |
| T5899 | 5300-5303 | Protein | denotes | CD4 |
| T5898 | 5264-5269 | Protein | denotes | SOCS3 |
| T5897 | 5254-5259 | Protein | denotes | SOCS1 |
| T5896 | 5225-5230 | Protein | denotes | IL-10 |
| T5895 | 5200-5205 | Protein | denotes | STAT3 |
| T5894 | 5190-5195 | Protein | denotes | STAT1 |
| T5861 | 2834-2839 | Protein | denotes | IL-10 |
| T5860 | 2465-2485 | Protein | denotes | pleiotropic cytokine |
| T5859 | 2455-2459 | Protein | denotes | IL-6 |
| T5858 | 2167-2171 | Protein | denotes | IL-1 |
| T5857 | 2156-2161 | Protein | denotes | TNF-α |
| T5856 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T5855 | 1721-1726 | Protein | denotes | IL-10 |
| T5854 | 1692-1696 | Protein | denotes | IL-6 |
| T5853 | 1664-1669 | Protein | denotes | STAT3 |
| T5852 | 1633-1637 | Protein | denotes | IL-6 |
| T5851 | 1623-1628 | Protein | denotes | IL-10 |
| T5850 | 1562-1567 | Protein | denotes | SOCS3 |
| T5849 | 1184-1188 | Protein | denotes | IL-6 |
| T5848 | 1082-1087 | Protein | denotes | IL-10 |
| T5847 | 1048-1053 | Protein | denotes | STAT3 |
| T5846 | 1011-1016 | Protein | denotes | STAT3 |
| T5845 | 937-941 | Protein | denotes | IL-6 |
| T5844 | 901-906 | Protein | denotes | IL-10 |
| T5843 | 869-874 | Protein | denotes | STAT3 |
| T5842 | 736-741 | Protein | denotes | STAT3 |
| T5841 | 726-731 | Protein | denotes | STAT1 |
| T5840 | 693-698 | Protein | denotes | STAT1 |
| T5839 | 631-688 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
| T5838 | 539-544 | Protein | denotes | IL-10 |
| T5837 | 376-382 | Protein | denotes | IL-10R |
| T5836 | 366-371 | Protein | denotes | IL-10 |
| T5835 | 506-519 | Protein | denotes | type 2 IL-10R |
| T5834 | 494-501 | Protein | denotes | IL-10R1 |
| T5833 | 447-451 | Protein | denotes | Tyk2 |
| T5832 | 438-442 | Protein | denotes | Jak1 |
| T5831 | 328-341 | Protein | denotes | type 2 IL-10R |
| T5830 | 291-298 | Protein | denotes | IL-10R1 |
| T5829 | 276-289 | Protein | denotes | type 1 IL-10R |
| T5828 | 189-195 | Protein | denotes | IL-10R |
| T5827 | 173-187 | Protein | denotes | IL-10 receptor |
| T5826 | 154-159 | Protein | denotes | IL-10 |
| T5825 | 14-18 | Protein | denotes | L-10 |
| T5866 | 3401-3408 | Protein | denotes | IL-10R1 |
| T5865 | 3339-3343 | Protein | denotes | IL-1 |
| T5864 | 3329-3334 | Protein | denotes | TNF-α |
| T5863 | 3227-3232 | Protein | denotes | IL-10 |
| T5862 | 3132-3137 | Protein | denotes | IL-10 |
| T5893 | 5166-5171 | Protein | denotes | IL-10 |
| T5892 | 5128-5132 | Protein | denotes | CD28 |
| T5891 | 5108-5113 | Protein | denotes | IFN-γ |
| T5890 | 5028-5031 | Protein | denotes | CD4 |
| T5889 | 4886-4890 | Protein | denotes | CD28 |
| T5888 | 4797-4802 | Protein | denotes | IL-10 |
| T5887 | 4768-4772 | Protein | denotes | CD86 |
| T5886 | 4759-4763 | Protein | denotes | CD80 |
| T5885 | 4729-4733 | Protein | denotes | CD28 |
| T5884 | 4644-4693 | Protein | denotes | cytotoxic T-cell-associated antigen 4 (CD152)-IgG |
| T5883 | 4343-4346 | Protein | denotes | CD4 |
| T5882 | 4315-4320 | Protein | denotes | IL-17 |
| T5881 | 4303-4310 | Protein | denotes | (IFN)-γ |
| T5880 | 4286-4302 | Protein | denotes | interferon gamma |
| T5879 | 4216-4220 | Protein | denotes | CD11 |
| T5878 | 4207-4211 | Protein | denotes | CD69 |
| T5877 | 4026-4029 | Protein | denotes | CD4 |
| T5876 | 3954-3958 | Protein | denotes | CD86 |
| T5875 | 3945-3949 | Protein | denotes | CD80 |
| T5874 | 3931-3935 | Protein | denotes | CD28 |
| T5873 | 3799-3812 | Protein | denotes | HLA-DRB1*0401 |
| T5872 | 3781-3794 | Protein | denotes | HLA-DRB1*0404 |
| T5871 | 3628-3632 | Protein | denotes | CD28 |
| T5870 | 3551-3554 | Protein | denotes | CD4 |
| T5869 | 3496-3544 | Protein | denotes | granulocyte–macrophage colony-stimulating factor |
| T5868 | 3486-3490 | Protein | denotes | IL-1 |
| T5867 | 3479-3484 | Protein | denotes | TNF-α |
| R2886 | T5826 | T5900 | themeOf | IL-10,binds |
| R2888 | T5826 | T5900 | themeOf | IL-10,binds |
| R2890 | T5827 | T5900 | themeOf | IL-10 receptor,binds |
| R2891 | T5828 | T5900 | themeOf | IL-10R,binds |
| R2892 | T5829 | T5901 | themeOf | type 1 IL-10R,ligand-binding |
| R2893 | T5829 | T5901 | themeOf | type 1 IL-10R,ligand-binding |
| R2895 | T5830 | T5901 | themeOf | IL-10R1,ligand-binding |
| R2896 | T5830 | T5901 | themeOf | IL-10R1,ligand-binding |
| R2897 | T5831 | T5901 | themeOf | type 2 IL-10R,ligand-binding |
| R2898 | T5831 | T5901 | themeOf | type 2 IL-10R,ligand-binding |
| R2899 | T5832 | T5903 | themeOf | Jak1,engages |
| R2900 | T5862 | T5921 | themeOf | IL-10,modulated |
| R2901 | T5833 | T5903 | themeOf | Tyk2,engages |
| R2902 | T5833 | T5903 | themeOf | Tyk2,engages |
| R2903 | T5836 | T5902 | themeOf | IL-10,interaction |
| R2904 | T5837 | T5902 | themeOf | IL-10R,interaction |
| R2905 | T5866 | T5922 | themeOf | IL-10R1,expression |
| R2906 | T5838 | T5906 | causeOf | IL-10,induces |
| R2907 | T5838 | T5906 | causeOf | IL-10,induces |
| R2908 | T5838 | T5906 | causeOf | IL-10,induces |
| R2909 | T5838 | T5906 | causeOf | IL-10,induces |
| R2910 | T5839 | T5904 | themeOf | signal transducer and activator of transcription (STAT) 3,phosphorylation |
| R2911 | T5840 | T5904 | themeOf | STAT1,phosphorylation |
| R2912 | T5841 | T5907 | themeOf | STAT1,phosphorylation |
| R2913 | T5841 | T5908 | themeOf | STAT1,translocate |
| R2914 | T5841 | T5909 | themeOf | STAT1,modulate |
| R2915 | T5842 | T5907 | themeOf | STAT3,phosphorylation |
| R2916 | T5842 | T5908 | themeOf | STAT3,translocate |
| R2917 | T5842 | T5909 | themeOf | STAT3,modulate |
| R2918 | T5872 | T5924 | themeOf | HLA-DRB1*0404,expression |
| R2919 | T5846 | T5910 | themeOf | STAT3,deficient |
| R2920 | T5847 | T5911 | themeOf | STAT3,activation |
| R2921 | T5848 | T5912 | themeOf | IL-10,mediated |
| R2922 | T5850 | T5916 | causeOf | SOCS3,blocking |
| R2923 | T5851 | T5913 | themeOf | IL-10,regulating |
| R2924 | T5852 | T5913 | themeOf | IL-6,regulating |
| R2925 | T5853 | T5914 | themeOf | STAT3,activation |
| R2926 | T5873 | T5924 | themeOf | HLA-DRB1*0401,expression |
| R2927 | T5854 | T5915 | causeOf | IL-6,induced |
| R2928 | T5874 | T5924 | themeOf | CD28,expression |
| R2929 | T5875 | T5924 | themeOf | CD80,expression |
| R2930 | T5859 | T5917 | themeOf | IL-6,produced |
| R2931 | T5860 | T5917 | themeOf | pleiotropic cytokine,produced |
| R2932 | T5861 | T5919 | themeOf | IL-10,produced |
| R2933 | T5861 | T5920 | themeOf | IL-10,expression |
| R2934 | T5876 | T5924 | themeOf | CD86,expression |
| R2935 | T5894 | T5931 | themeOf | STAT1,induction |
| R2936 | T5894 | T5932 | themeOf | STAT1,phosphorylation |
| R2937 | T5895 | T5931 | themeOf | STAT3,induction |
| R2938 | T5895 | T5932 | themeOf | STAT3,phosphorylation |
| R2939 | T5896 | T5931 | causeOf | IL-10,induction |
| R2940 | T5896 | T5931 | causeOf | IL-10,induction |
| R2941 | T5896 | T5931 | causeOf | IL-10,induction |
| R2942 | T5896 | T5931 | causeOf | IL-10,induction |
| R2943 | T5896 | T5931 | causeOf | IL-10,induction |
| R2944 | T5897 | T5933 | themeOf | SOCS1,expression |
| R2945 | T5898 | T5933 | themeOf | SOCS3,expression |
| R2946 | T5884 | T5926 | themeOf | cytotoxic T-cell-associated antigen 4 (CD152)-IgG,binding |
| R2947 | T5904 | T5905 | themeOf | phosphorylation,activation |
| R2948 | T5904 | T5906 | themeOf | phosphorylation,induces |
| R2949 | T5904 | T5905 | themeOf | phosphorylation,activation |
| R2950 | T5904 | T5906 | themeOf | phosphorylation,induces |
| R2951 | T5905 | T5906 | themeOf | activation,induces |
| R2952 | T5905 | T5906 | themeOf | activation,induces |
| R2953 | T5907 | T5909 | themeOf | phosphorylation,modulate |
| R2954 | T5907 | T5909 | themeOf | phosphorylation,modulate |
| R2955 | T5884 | T5926 | themeOf | cytotoxic T-cell-associated antigen 4 (CD152)-IgG,binding |
| R2956 | T5885 | T5925 | themeOf | CD28,engagement |
| R2957 | T5914 | T5915 | themeOf | activation,induced |
| R2958 | T5914 | T5916 | themeOf | activation,blocking |
| R2959 | T5915 | T5914 | themeOf | induced,activation |
| R2960 | T5886 | T5926 | themeOf | CD80,binding |
| R2961 | T5917 | T5918 | themeOf | produced,activated |
| R2962 | T5917 | T5918 | themeOf | produced,activated |
| R2963 | T5886 | T5926 | themeOf | CD80,binding |
| R2964 | T5887 | T5926 | themeOf | CD86,binding |
| R2965 | T5887 | T5926 | themeOf | CD86,binding |
| R2966 | T5922 | T5923 | themeOf | expression,decreased |
| R2967 | T5888 | T5928 | causeOf | IL-10,inhibiting |
| R2968 | T5889 | T5928 | themeOf | CD28,inhibiting |
| R2969 | T5891 | T5929 | themeOf | IFN-γ,production |
| R2970 | T5925 | T5927 | themeOf | engagement,block |
| R2971 | T5925 | T5927 | themeOf | engagement,block |
| R2972 | T5925 | T5927 | themeOf | engagement,block |
| R2973 | T5926 | T5927 | causeOf | binding,block |
| R2974 | T5926 | T5927 | causeOf | binding,block |
| R2975 | T5926 | T5927 | causeOf | binding,block |
| R2976 | T5892 | T5930 | themeOf | CD28,costimulation |
| R2977 | T5929 | T5934 | themeOf | production,investigated |
| R2978 | T5929 | T5930 | themeOf | production,costimulation |
| R2979 | T5929 | T5931 | themeOf | production,induction |
| R2980 | T5931 | T5934 | themeOf | induction,investigated |
| R2981 | T5931 | T5934 | themeOf | induction,investigated |
| R2982 | T5931 | T5934 | themeOf | induction,investigated |
| R2984 | T5932 | T5931 | themeOf | phosphorylation,induction |
| R2985 | T5932 | T5931 | themeOf | phosphorylation,induction |
| R2986 | T5933 | T5934 | themeOf | expression,investigated |
| R2987 | T5933 | T5934 | themeOf | expression,investigated |
bionlp-st-ge-2016-test-ihmc
| Id | Subject | Object | Predicate | Lexical cue | Speculation |
|---|---|---|---|---|---|
| T6250 | 726-731 | Protein | denotes | STAT1 | |
| T6249 | 1633-1637 | Protein | denotes | IL-6 | |
| T6248 | 2300-2308 | Entity | denotes | effector | |
| T6247 | 4264-4285 | Protein | denotes | Th1 cytokines such as | |
| T6246 | 391-442 | Protein | denotes | the Janus kinase (JAK) family tyrosine kinases Jak1 | |
| T6245 | 3963-3986 | Protein | denotes | the inflamed ST [18-20] | |
| T6355 | 453-519 | Binding | denotes | which are constitutively associated with IL-10R1 and type 2 IL-10R | |
| T6354 | 347-382 | Binding | denotes | The interaction of IL-10 and IL-10R | |
| T6353 | 1664-1726 | Positive_regulation | denotes | STAT3 activation induced by IL-6 but not that induced by IL-10 | |
| T6352 | 4748-4795 | Binding | denotes | binding to CD80 and CD86 with high avidity [23] | |
| T6351 | 3374-3408 | Gene_expression | denotes | Cell surface expression of IL-10R1 | |
| T6350 | 3628-3672 | Regulation | denotes | CD28-mediated costimulatory signaling, in RA | |
| T6349 | 239-299 | Binding | denotes | the primary ligand-binding component type 1 IL-10R (IL-10R1) | |
| T6348 | 5128-5146 | Positive_regulation | denotes | CD28 costimulation | |
| T6347 | 835-853 | Transcription | denotes | gene transcription | |
| T6346 | 154-204 | Binding | denotes | IL-10 binds to the IL-10 receptor (IL-10R) complex | |
| T6345 | 726-853 | Regulation | denotes | STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription | |
| T6344 | 726-853 | Regulation | denotes | STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription | |
| T6284 | 5200-5205 | Protein | denotes | STAT3 | |
| T6283 | 693-702 | Protein | denotes | STAT1 [3] | |
| T6197 | 2635-2666 | Entity | denotes | plasma cells, T-cell functions, | |
| T6196 | 2463-2533 | Protein | denotes | a pleiotropic cytokine produced substantially by activated fibroblasts | |
| T6195 | 3129-3137 | Protein | denotes | of IL-10 | |
| T6194 | 2127-2162 | Protein | denotes | Tumor necrosis factor alpha (TNF-α) | |
| T6193 | 4633-4694 | Protein | denotes | protein of cytotoxic T-cell-associated antigen 4 (CD152)-IgG, | |
| T6192 | 3508-3518 | Entity | denotes | macrophage | |
| T6191 | 1048-1053 | Protein | denotes | STAT3 | |
| T6190 | 869-874 | Protein | denotes | STAT3 | |
| T6189 | 3398-3408 | Protein | denotes | of IL-10R1 | |
| T6188 | 770-821 | Entity | denotes | heterodimers, rapidly translocate into the nucleus, | |
| T6187 | 3755-3794 | Protein | denotes | the MHC class II antigens HLA-DRB1*0404 | |
| T6186 | 124-152 | Protein | denotes | of proinflammatory cytokines | |
| T6185 | 4159-4171 | Entity | denotes | cell surface | |
| T6184 | 2823-2825 | Protein | denotes | RA | |
| T6183 | 4768-4772 | Protein | denotes | CD86 | |
| T6182 | 1950-1971 | Entity | denotes | fibroblast-like cells | |
| T6181 | 5313-5320 | Protein | denotes | from RA | |
| T6180 | 4194-4211 | Protein | denotes | cell surface CD69 | |
| T6179 | 3496-3549 | Protein | denotes | granulocyte–macrophage colony-stimulating factor [15] | |
| T6178 | 304-341 | Protein | denotes | the accessory component type 2 IL-10R | |
| T6177 | 2649-2655 | Entity | denotes | T-cell | |
| T6176 | 1718-1726 | Protein | denotes | by IL-10 | |
| T6175 | 2052-2072 | Entity | denotes | synovial fibroblasts | |
| T6174 | 2407-2419 | Entity | denotes | nitric oxide | |
| T6173 | 4343-4355 | Entity | denotes | CD4+ T cells | |
| T6172 | 4603-4609 | Entity | denotes | T-cell | |
| T6171 | 291-298 | Protein | denotes | IL-10R1 | |
| T6170 | 3931-3935 | Protein | denotes | CD28 | |
| T6169 | 391-442 | Protein | denotes | the Janus kinase (JAK) family tyrosine kinases Jak1 | |
| T6168 | 756-766 | Entity | denotes | homodimers | |
| T6167 | 239-299 | Entity | denotes | the primary ligand-binding component type 1 IL-10R (IL-10R1) | |
| T6166 | 3670-3672 | Protein | denotes | RA | |
| T6165 | 2361-2371 | Protein | denotes | chemokines | |
| T6164 | 1781-1783 | Protein | denotes | RA | |
| T6163 | 2911-2913 | Protein | denotes | ST | |
| T6244 | 2958-2968 | Entity | denotes | macrophage | |
| T6243 | 4264-4296 | Protein | denotes | Th1 cytokines such as interferon | |
| T6242 | 3295-3328 | Protein | denotes | proinflammatory cytokines such as | |
| T6241 | 809-820 | Entity | denotes | the nucleus | |
| T6240 | 5025-5040 | Entity | denotes | of CD4+ T cells | |
| T6239 | 4644-4694 | Protein | denotes | cytotoxic T-cell-associated antigen 4 (CD152)-IgG, | |
| T6238 | 2389-2405 | Protein | denotes | matrix proteases | |
| T6237 | 1893-1908 | Entity | denotes | dendritic cells | |
| T6236 | 3899-3921 | Entity | denotes | MHC class II molecules | |
| T6235 | 1973-1991 | Protein | denotes | Numerous cytokines | |
| T6234 | 506-519 | Protein | denotes | type 2 IL-10R | |
| T6233 | 4372-4433 | Protein | denotes | B-cell production of autoantibodies such as rheumatoid factor | |
| T6232 | 1276-1280 | Protein | denotes | SOCS | |
| T6231 | 1480-1507 | Protein | denotes | cytokine signaling pathways | |
| T6230 | 421-429 | Entity | denotes | tyrosine | |
| T6229 | 3628-3641 | Protein | denotes | CD28-mediated | |
| T6228 | 937-949 | Protein | denotes | IL-6-derived | |
| T6227 | 401-413 | Protein | denotes | kinase (JAK) | |
| T6226 | 5105-5113 | Protein | denotes | of IFN-γ | |
| T6225 | 22-36 | Protein | denotes | a key cytokine | |
| T6224 | 1327-1359 | Protein | denotes | endogenous JAK kinase inhibitors | |
| T6223 | 5264-5269 | Protein | denotes | SOCS3 | |
| T6222 | 2455-2459 | Protein | denotes | IL-6 | |
| T6221 | 1664-1669 | Protein | denotes | STAT3 | |
| T6220 | 2671-2699 | Entity | denotes | hematopoietic precursor cell | |
| T6219 | 376-382 | Protein | denotes | IL-10R | |
| T6218 | 4216-4220 | Protein | denotes | CD11 | |
| T6217 | 2834-2864 | Protein | denotes | IL-10, produced by macrophages | |
| T6216 | 593-688 | Protein | denotes | of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 | |
| T6215 | 366-371 | Protein | denotes | IL-10 | |
| T6214 | 3926-3943 | Entity | denotes | both CD28 ligands | |
| T6213 | 1562-1567 | Protein | denotes | SOCS3 | |
| T6212 | 1832-1853 | Entity | denotes | of inflammatory cells | |
| T6211 | 1338-1341 | Protein | denotes | JAK | |
| T6210 | 3581-3607 | Entity | denotes | by arthritogenic antigens, | |
| T6209 | 3374-3386 | Entity | denotes | Cell surface | |
| T6208 | 494-501 | Protein | denotes | IL-10R1 | |
| T6207 | 4968-4978 | Entity | denotes | of antigen | |
| T6206 | 4130-4150 | Entity | denotes | synovial fibroblasts | |
| T6205 | 3772-3780 | Entity | denotes | antigens | |
| T6204 | 3100-3137 | Entity | denotes | the anti-inflammatory action of IL-10 | |
| T6203 | 4886-4890 | Protein | denotes | CD28 | |
| T6202 | 1950-1971 | Entity | denotes | fibroblast-like cells | |
| T6201 | 4990-4995 | Entity | denotes | cells | |
| T6200 | 4390-4407 | Protein | denotes | of autoantibodies | |
| T6199 | 835-839 | Protein | denotes | gene | |
| T6198 | 395-400 | Protein | denotes | Janus | |
| T6282 | 1082-1096 | Protein | denotes | IL-10-mediated | |
| T6281 | 3496-3518 | Entity | denotes | granulocyte–macrophage | |
| T6280 | 5222-5230 | Protein | denotes | by IL-10 | |
| T6279 | 1689-1696 | Protein | denotes | by IL-6 | |
| T6278 | 4114-4125 | Entity | denotes | macrophages | |
| T6277 | 2763-2782 | Protein | denotes | cytokine inhibitors | |
| T6276 | 3258-3269 | Entity | denotes | macrophages | |
| T6275 | 1238-1281 | Protein | denotes | The suppressor of cytokine signaling (SOCS) | |
| T6274 | 166-204 | Protein | denotes | to the IL-10 receptor (IL-10R) complex | |
| T6273 | 2156-2161 | Protein | denotes | TNF-α | |
| T6272 | 736-741 | Protein | denotes | STAT3 | |
| T6271 | 2879-2915 | Entity | denotes | T cells in the synovial tissue (ST), | |
| T6270 | 5120-5123 | Protein | denotes | CD3 | |
| T6269 | 2331-2359 | Protein | denotes | other inflammatory cytokines | |
| T6268 | 3551-3563 | Entity | denotes | CD4+ T cells | |
| T6267 | 1184-1197 | Protein | denotes | IL-6-mediated | |
| T6266 | 5305-5312 | Entity | denotes | T cells | |
| T6265 | 3227-3232 | Protein | denotes | IL-10 | |
| T6264 | 2512-2533 | Entity | denotes | activated fibroblasts | |
| T6263 | 553-577 | Entity | denotes | tyrosine phosphorylation | |
| T6262 | 2763-2782 | Entity | denotes | cytokine inhibitors | |
| T6261 | 5254-5259 | Protein | denotes | SOCS1 | |
| T6260 | 3496-3518 | Entity | denotes | granulocyte–macrophage | |
| T6259 | 409-412 | Protein | denotes | JAK | |
| T6258 | 4797-4802 | Protein | denotes | IL-10 | |
| T6257 | 3348-3372 | Entity | denotes | immune complexes [13,14] | |
| T6256 | 539-544 | Protein | denotes | IL-10 | |
| T6255 | 4826-4842 | Entity | denotes | antigen-specific | |
| T6254 | 3954-3958 | Protein | denotes | CD86 | |
| T6253 | 5166-5171 | Protein | denotes | IL-10 | |
| T6252 | 4372-4378 | Entity | denotes | B-cell | |
| T6251 | 3755-3794 | Protein | denotes | the MHC class II antigens HLA-DRB1*0404 | |
| T6299 | 5128-5132 | Protein | denotes | CD28 | |
| T6298 | 1027-1031 | Protein | denotes | mice | |
| T6297 | 189-195 | Protein | denotes | IL-10R | |
| T6296 | 1961-1971 | Entity | denotes | like cells | |
| T6295 | 989-1016 | Protein | denotes | of cell-type-specific STAT3 | |
| T6294 | 1128-1139 | Entity | denotes | macrophages | |
| T6293 | 2173-2202 | Entity | denotes | two major macrophage products | |
| T6292 | 4759-4763 | Protein | denotes | CD80 | |
| T6291 | 4315-4320 | Protein | denotes | IL-17 | |
| T6290 | 3486-3490 | Protein | denotes | IL-1 | |
| T6289 | 13-18 | Protein | denotes | IL-10 | |
| T6288 | 2183-2193 | Entity | denotes | macrophage | |
| T6287 | 1863-1874 | Entity | denotes | lymphocytes | |
| T6286 | 1623-1628 | Protein | denotes | IL-10 | |
| T6285 | 4438-4457 | Entity | denotes | osteoclast-mediated | |
| T6343 | 4579-4620 | Negative_regulation | denotes | selective inhibition of T-cell activation | |
| T6342 | 3227-3242 | Positive_regulation | denotes | IL-10 signaling | |
| T6341 | 1639-1726 | Negative_regulation | denotes | by specifically blocking STAT3 activation induced by IL-6 but not that induced by IL-10 | |
| T6340 | 4330-4433 | Positive_regulation | denotes | In addition, CD4+ T cells could stimulate B-cell production of autoantibodies such as rheumatoid factor | true |
| T6339 | 4501-4503 | Protein | denotes | RA | |
| T6338 | 4194-4206 | Entity | denotes | cell surface | |
| T6337 | 3479-3484 | Protein | denotes | TNF-α | |
| T6336 | 1225-1236 | Entity | denotes | T cells [6] | |
| T6335 | 2853-2864 | Entity | denotes | macrophages | |
| T6334 | 4822-4867 | Protein | denotes | the antigen-specific T-cell cytokine response | |
| T6333 | 4729-4733 | Protein | denotes | CD28 | |
| T6332 | 3295-3334 | Protein | denotes | proinflammatory cytokines such as TNF-α | |
| T6331 | 2097-2125 | Protein | denotes | of proinflammatory cytokines | |
| T6330 | 447-451 | Protein | denotes | Tyk2 | |
| T6329 | 4843-4849 | Entity | denotes | T-cell | |
| T6328 | 5300-5303 | Protein | denotes | CD4 | |
| T6327 | 2036-2047 | Entity | denotes | macrophages | |
| T6326 | 1282-1290 | Protein | denotes | proteins | |
| T6325 | 4304-4307 | Protein | denotes | IFN | |
| T6324 | 5296-5298 | Protein | denotes | PB | |
| T6323 | 2167-2203 | Protein | denotes | IL-1, two major macrophage products, | |
| T6322 | 154-159 | Protein | denotes | IL-10 | |
| T6321 | 1327-1359 | Entity | denotes | endogenous JAK kinase inhibitors | |
| T6320 | 3899-3911 | Protein | denotes | MHC class II | |
| T6319 | 2731-2758 | Entity | denotes | anti-inflammatory cytokines | |
| T6318 | 4737-4744 | Entity | denotes | T cells | |
| T6317 | 1082-1160 | Entity | denotes | IL-10-mediated anti-inflammatory reactions in macrophages and neutrophils [5], | |
| T6316 | 1144-1155 | Entity | denotes | neutrophils | |
| T6315 | 1876-1887 | Entity | denotes | macrophages | |
| T6314 | 3945-3949 | Protein | denotes | CD80 | |
| T6313 | 901-932 | Entity | denotes | IL-10-derived anti-inflammatory | |
| T6312 | 2973-2982 | Entity | denotes | Th1 cells | |
| T6311 | 736-750 | Protein | denotes | STAT3 proteins | |
| T6310 | 1327-1359 | Protein | denotes | endogenous JAK kinase inhibitors | |
| T6309 | 5190-5195 | Protein | denotes | STAT1 | |
| T6308 | 3440-3549 | Entity | denotes | dendritic cells due to the presence of TNF-α, IL-1, and granulocyte–macrophage colony-stimulating factor [15] | |
| T6307 | 901-914 | Protein | denotes | IL-10-derived | |
| T6306 | 166-204 | Entity | denotes | to the IL-10 receptor (IL-10R) complex | |
| T6305 | 5070-5072 | Protein | denotes | RA | |
| T6304 | 266-299 | Protein | denotes | component type 1 IL-10R (IL-10R1) | |
| T6303 | 3339-3343 | Protein | denotes | IL-1 | |
| T6302 | 2731-2758 | Protein | denotes | anti-inflammatory cytokines | |
| T6301 | 3799-3825 | Protein | denotes | HLA-DRB1*0401 with disease | |
| T6300 | 4016-4038 | Entity | denotes | activated CD4+ T cells | |
| T6374 | 582-688 | Positive_regulation | denotes | activation of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 | |
| T6373 | 3496-3549 | Localization | denotes | granulocyte–macrophage colony-stimulating factor [15] | |
| T6372 | 1168-1221 | Regulation | denotes | responsible for IL-6-mediated prevention of apoptosis | |
| T6371 | 4194-4212 | Localization | denotes | cell surface CD69 | |
| T6370 | 4438-4474 | Regulation | denotes | osteoclast-mediated bone destruction | |
| T6369 | 1037-1064 | Positive_regulation | denotes | shown that STAT3 activation | |
| T6368 | 3227-3343 | Negative_regulation | denotes | IL-10 signaling is impaired in macrophages upon chronic exposure to proinflammatory cytokines such as TNF-α and IL-1 | |
| T6367 | 5236-5269 | Gene_expression | denotes | the expression of SOCS1 and SOCS3 | |
| T6366 | 5236-5269 | Gene_expression | denotes | the expression of SOCS1 and SOCS3 | |
| T6365 | 2834-2864 | Gene_expression | denotes | IL-10, produced by macrophages | |
| T6364 | 5173-5205 | Gene_expression | denotes | the induction of STAT1 and STAT3 | |
| T6363 | 5173-5205 | Positive_regulation | denotes | the induction of STAT1 and STAT3 | |
| T6362 | 5173-5205 | Positive_regulation | denotes | the induction of STAT1 and STAT3 | |
| T6361 | 5173-5205 | Gene_expression | denotes | the induction of STAT1 and STAT3 | |
| T6360 | 4372-4415 | Gene_expression | denotes | B-cell production of autoantibodies such as | |
| T6359 | 1973-2030 | Gene_expression | denotes | Numerous cytokines are overproduced in the inflamed joint | |
| T6358 | 1973-2030 | Positive_regulation | denotes | Numerous cytokines are overproduced in the inflamed joint | |
| T6357 | 5077-5113 | Gene_expression | denotes | investigated the production of IFN-γ | |
| T6356 | 453-519 | Binding | denotes | which are constitutively associated with IL-10R1 and type 2 IL-10R | |
| R3098 | T6199 | T6347 | themeOf | gene,gene transcription | |
| R3100 | T6200 | T6360 | themeOf | of autoantibodies,B-cell production of autoantibodies such as | |
| R3101 | T6208 | T6356 | themeOf | IL-10R1,which are constitutively associated with IL-10R1 and type 2 IL-10R | |
| R3102 | T6179 | T6373 | themeOf | granulocyte–macrophage colony-stimulating factor [15],granulocyte–macrophage colony-stimulating factor [15] | |
| R3103 | T6180 | T6371 | themeOf | cell surface CD69,cell surface CD69 | |
| R3104 | T6183 | T6352 | themeOf | CD86,binding to CD80 and CD86 with high avidity [23] | |
| R3105 | T6215 | T6354 | themeOf | IL-10,The interaction of IL-10 and IL-10R | |
| R3106 | T6189 | T6351 | themeOf | of IL-10R1,Cell surface expression of IL-10R1 | |
| R3107 | T6191 | T6369 | themeOf | STAT3,shown that STAT3 activation | |
| R3108 | T6216 | T6374 | themeOf | of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3,activation of the latent transcriptional factors signal transducer and activator of transcription (STAT) 3 | |
| R3109 | T6217 | T6365 | themeOf | "IL-10, produced by macrophages","IL-10, produced by macrophages" | |
| R3110 | T6219 | T6354 | themeOf | IL-10R,The interaction of IL-10 and IL-10R | |
| R3111 | T6221 | T6353 | themeOf | STAT3,STAT3 activation induced by IL-6 but not that induced by IL-10 | |
| R3112 | T6223 | T6366 | themeOf | SOCS3,the expression of SOCS1 and SOCS3 | |
| R3113 | T6226 | T6357 | themeOf | of IFN-γ,investigated the production of IFN-γ | |
| R3114 | T6260 | T6373 | locationOf | granulocyte–macrophage,granulocyte–macrophage colony-stimulating factor [15] | |
| R3115 | T6229 | T6350 | causeOf | CD28-mediated,"CD28-mediated costimulatory signaling, in RA" | |
| R3116 | T6261 | T6367 | themeOf | SOCS1,the expression of SOCS1 and SOCS3 | |
| R3118 | T6265 | T6342 | causeOf | IL-10,IL-10 signaling | |
| R3119 | T6267 | T6372 | causeOf | IL-6-mediated,responsible for IL-6-mediated prevention of apoptosis | |
| R3120 | T6234 | T6355 | themeOf | type 2 IL-10R,which are constitutively associated with IL-10R1 and type 2 IL-10R | |
| R3121 | T6235 | T6358 | themeOf | Numerous cytokines,Numerous cytokines are overproduced in the inflamed joint | |
| R3122 | T6235 | T6359 | themeOf | Numerous cytokines,Numerous cytokines are overproduced in the inflamed joint | |
| R3123 | T6250 | T6345 | causeOf | STAT1,"STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription" | |
| R3124 | T6284 | T6363 | themeOf | STAT3,the induction of STAT1 and STAT3 | |
| R3125 | T6284 | T6364 | themeOf | STAT3,the induction of STAT1 and STAT3 | |
| R3126 | T6285 | T6370 | causeOf | osteoclast-mediated,osteoclast-mediated bone destruction | |
| R3127 | T6292 | T6352 | themeOf | CD80,binding to CD80 and CD86 with high avidity [23] | |
| R3128 | T6304 | T6349 | themeOf | component type 1 IL-10R (IL-10R1),the primary ligand-binding component type 1 IL-10R (IL-10R1) | |
| R3129 | T6299 | T6348 | themeOf | CD28,CD28 costimulation | |
| R3130 | T6306 | T6346 | themeOf | to the IL-10 receptor (IL-10R) complex,IL-10 binds to the IL-10 receptor (IL-10R) complex | |
| R3131 | T6309 | T6361 | themeOf | STAT1,the induction of STAT1 and STAT3 | |
| R3132 | T6353 | T6341 | themeOf | STAT3 activation induced by IL-6 but not that induced by IL-10,by specifically blocking STAT3 activation induced by IL-6 but not that induced by IL-10 | |
| R3133 | T6309 | T6362 | themeOf | STAT1,the induction of STAT1 and STAT3 | |
| R3134 | T6311 | T6344 | causeOf | STAT3 proteins,"STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription" | |
| R3135 | T6322 | T6346 | themeOf | IL-10,IL-10 binds to the IL-10 receptor (IL-10R) complex | |
| R3136 | T6338 | T6371 | locationOf | cell surface,cell surface CD69 | |
| R3141 | T6342 | T6368 | themeOf | IL-10 signaling,IL-10 signaling is impaired in macrophages upon chronic exposure to proinflammatory cytokines such as TNF-α and IL-1 | |
| R3144 | T6347 | T6344 | themeOf | gene transcription,"STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription" | |
| R3147 | T6347 | T6345 | themeOf | gene transcription,"STAT1 and STAT3 proteins form homodimers or heterodimers, rapidly translocate into the nucleus, and modulate gene transcription" | |
| R3099 | T6173 | T6340 | causeOf | CD4+ T cells,"In addition, CD4+ T cells could stimulate B-cell production of autoantibodies such as rheumatoid factor" | |
| R3117 | T6233 | T6340 | themeOf | B-cell production of autoantibodies such as rheumatoid factor,"In addition, CD4+ T cells could stimulate B-cell production of autoantibodies such as rheumatoid factor" |
bionlp-st-ge-2016-spacy-parsed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T5729 | 4795-4796 | . | denotes | . |
| T5728 | 4794-4795 | NNP | denotes | ] |
| T5727 | 4792-4794 | CD | denotes | 23 |
| T5726 | 4791-4792 | NNP | denotes | [ |
| T5725 | 4783-4790 | NN | denotes | avidity |
| T5724 | 4778-4782 | JJ | denotes | high |
| T5723 | 4773-4777 | IN | denotes | with |
| T5722 | 4768-4772 | NNP | denotes | CD86 |
| T5721 | 4764-4767 | CC | denotes | and |
| T5720 | 4759-4763 | NNP | denotes | CD80 |
| T5719 | 4756-4758 | TO | denotes | to |
| T5718 | 4748-4755 | JJ | denotes | binding |
| T5717 | 4745-4747 | IN | denotes | by |
| T5716 | 4739-4744 | NNS | denotes | cells |
| T5715 | 4737-4738 | NNP | denotes | T |
| T5714 | 4734-4736 | IN | denotes | on |
| T5713 | 4729-4733 | CD | denotes | CD28 |
| T5712 | 4726-4728 | IN | denotes | of |
| T5711 | 4715-4725 | NN | denotes | engagement |
| T5710 | 4711-4714 | DT | denotes | the |
| T5703 | 4688-4689 | -RRB- | denotes | ) |
| T5702 | 4683-4688 | NN | denotes | CD152 |
| T5701 | 4682-4683 | -LRB- | denotes | ( |
| T5700 | 4680-4681 | CD | denotes | 4 |
| T5699 | 4672-4679 | NN | denotes | antigen |
| T5698 | 4654-4671 | JJ | denotes | T-cell-associated |
| T5697 | 4644-4653 | JJ | denotes | cytotoxic |
| T5696 | 4641-4643 | IN | denotes | of |
| T5695 | 4633-4640 | NN | denotes | protein |
| T5694 | 4626-4632 | NN | denotes | fusion |
| T5693 | 4621-4625 | IN | denotes | with |
| T5692 | 4610-4620 | NN | denotes | activation |
| T5691 | 4603-4609 | NNP | denotes | T-cell |
| T5690 | 4600-4602 | IN | denotes | of |
| T5689 | 4589-4599 | NN | denotes | inhibition |
| T5688 | 4579-4588 | JJ | denotes | selective |
| T5687 | 4576-4578 | IN | denotes | by |
| T5686 | 4568-4575 | NN | denotes | disease |
| T5685 | 4561-4567 | JJ | denotes | active |
| T5684 | 4558-4560 | IN | denotes | of |
| T5683 | 4548-4557 | NN | denotes | treatment |
| T5682 | 4537-4547 | JJ | denotes | successful |
| T5681 | 4534-4536 | IN | denotes | by |
| T5680 | 4527-4533 | VBN | denotes | proved |
| T5679 | 4518-4526 | RB | denotes | recently |
| T5678 | 4514-4517 | VBD | denotes | was |
| T5677 | 4504-4513 | NN | denotes | synovitis |
| T5676 | 4501-4503 | NNP | denotes | RA |
| T5675 | 4498-4500 | IN | denotes | in |
| T5674 | 4493-4497 | NN | denotes | role |
| T5673 | 4482-4492 | JJ | denotes | obligatory |
| T5672 | 4476-4481 | PRP$ | denotes | Their |
| T5671 | 4474-4475 | . | denotes | . |
| T5670 | 4463-4474 | NN | denotes | destruction |
| T5669 | 4458-4462 | NN | denotes | bone |
| T5668 | 4438-4457 | JJ | denotes | osteoclast-mediated |
| T5667 | 4434-4437 | CC | denotes | and |
| T5666 | 4427-4433 | NN | denotes | factor |
| T5665 | 4416-4426 | JJ | denotes | rheumatoid |
| T5664 | 4413-4415 | IN | denotes | as |
| T5663 | 4408-4412 | JJ | denotes | such |
| T5662 | 4393-4407 | NNS | denotes | autoantibodies |
| T5661 | 4390-4392 | IN | denotes | of |
| T5603 | 4074-4081 | JJ | denotes | crucial |
| T5602 | 4071-4073 | VB | denotes | be |
| T5601 | 4067-4070 | MD | denotes | may |
| T5600 | 4065-4066 | , | denotes | , |
| T5599 | 4059-4065 | NN | denotes | number |
| T5598 | 4056-4058 | IN | denotes | in |
| T5597 | 4052-4055 | JJ | denotes | few |
| T5596 | 4045-4051 | IN | denotes | though |
| T5595 | 4040-4044 | RB | denotes | even |
| T5594 | 4038-4039 | , | denotes | , |
| T5593 | 4033-4038 | NNS | denotes | cells |
| T5592 | 4031-4032 | NNP | denotes | T |
| T5591 | 4029-4030 | CD | denotes | + |
| T5590 | 4026-4029 | NNP | denotes | CD4 |
| T5589 | 4016-4025 | VBN | denotes | activated |
| T5588 | 4013-4015 | IN | denotes | of |
| T5587 | 4003-4012 | NN | denotes | emergence |
| T5586 | 3992-4002 | VBG | denotes | continuing |
| T5585 | 3988-3991 | DT | denotes | The |
| T5584 | 3986-3987 | . | denotes | . |
| T5583 | 3985-3986 | NNP | denotes | ] |
| T5582 | 3980-3985 | CD | denotes | 18-20 |
| T5581 | 3979-3980 | NNP | denotes | [ |
| T5580 | 3976-3978 | NNP | denotes | ST |
| T5579 | 3967-3975 | JJ | denotes | inflamed |
| T5578 | 3963-3966 | DT | denotes | the |
| T5577 | 3960-3962 | IN | denotes | in |
| T5576 | 3958-3959 | , | denotes | , |
| T5575 | 3954-3958 | NNP | denotes | CD86 |
| T5574 | 3950-3953 | CC | denotes | and |
| T5573 | 3945-3949 | NNP | denotes | CD80 |
| T5572 | 3943-3944 | , | denotes | , |
| T5571 | 3936-3943 | NNS | denotes | ligands |
| T5570 | 3931-3935 | CD | denotes | CD28 |
| T5569 | 3926-3930 | DT | denotes | both |
| T5568 | 3922-3925 | CC | denotes | and |
| T5567 | 3912-3921 | NNS | denotes | molecules |
| T5566 | 3909-3911 | NNP | denotes | II |
| T5565 | 3903-3908 | NN | denotes | class |
| T5564 | 3899-3902 | NNP | denotes | MHC |
| T5563 | 3896-3898 | IN | denotes | of |
| T5562 | 3885-3895 | NN | denotes | expression |
| T5561 | 3874-3884 | JJ | denotes | high-level |
| T5560 | 3870-3873 | DT | denotes | the |
| T5559 | 3867-3869 | IN | denotes | by |
| T5558 | 3863-3866 | CC | denotes | and |
| T5557 | 3861-3862 | , | denotes | , |
| T5556 | 3860-3861 | NNP | denotes | ] |
| T5555 | 3855-3860 | CD | denotes | 16,17 |
| T5554 | 3854-3855 | NNP | denotes | [ |
| T5553 | 3845-3853 | NN | denotes | severity |
| T5552 | 3841-3844 | CC | denotes | and |
| T5551 | 3826-3840 | NN | denotes | susceptibility |
| T5550 | 3818-3825 | NN | denotes | disease |
| T5549 | 3813-3817 | IN | denotes | with |
| T5548 | 3808-3812 | CD | denotes | 0401 |
| T5547 | 3807-3808 | SYM | denotes | * |
| T5546 | 3799-3807 | NNP | denotes | HLA-DRB1 |
| T5545 | 3795-3798 | CC | denotes | and |
| T5544 | 3790-3794 | CD | denotes | 0404 |
| T5543 | 3789-3790 | SYM | denotes | * |
| T5542 | 3781-3789 | NNP | denotes | HLA-DRB1 |
| T5541 | 3772-3780 | VBZ | denotes | antigens |
| T5540 | 3769-3771 | NNP | denotes | II |
| T5539 | 3763-3768 | NN | denotes | class |
| T5538 | 3759-3762 | NNP | denotes | MHC |
| T5537 | 3755-3758 | DT | denotes | the |
| T5536 | 3752-3754 | IN | denotes | of |
| T5535 | 3744-3751 | NN | denotes | linkage |
| T5534 | 3740-3743 | DT | denotes | the |
| T5533 | 3737-3739 | IN | denotes | by |
| T5532 | 3727-3736 | VBN | denotes | supported |
| T5531 | 3722-3726 | VBN | denotes | been |
| T5530 | 3718-3721 | VBZ | denotes | has |
| T5529 | 3710-3717 | NN | denotes | process |
| T5528 | 3699-3709 | JJ | denotes | autoimmune |
| T5527 | 3694-3698 | DT | denotes | this |
| T5526 | 3691-3693 | IN | denotes | of |
| T5525 | 3678-3690 | NN | denotes | significance |
| T5524 | 3674-3677 | DT | denotes | The |
| T5523 | 3672-3673 | . | denotes | . |
| T5522 | 3670-3672 | NNP | denotes | RA |
| T5521 | 3667-3669 | IN | denotes | in |
| T5520 | 3665-3666 | , | denotes | , |
| T5519 | 3656-3665 | VBG | denotes | signaling |
| T5518 | 3642-3655 | JJ | denotes | costimulatory |
| T5517 | 3628-3641 | JJ | denotes | CD28-mediated |
| T5516 | 3623-3627 | IN | denotes | with |
| T5515 | 3611-3622 | NN | denotes | conjunction |
| T5514 | 3608-3610 | IN | denotes | in |
| T5310 | 2396-2405 | NNS | denotes | proteases |
| T5309 | 2389-2395 | NN | denotes | matrix |
| T5308 | 2387-2388 | , | denotes | , |
| T5307 | 2380-2387 | NNS | denotes | factors |
| T5306 | 2373-2379 | NN | denotes | growth |
| T5305 | 2371-2372 | , | denotes | , |
| T5304 | 2361-2371 | NNS | denotes | chemokines |
| T5303 | 2359-2360 | , | denotes | , |
| T5302 | 2350-2359 | NNS | denotes | cytokines |
| T5301 | 2337-2349 | JJ | denotes | inflammatory |
| T5300 | 2331-2336 | JJ | denotes | other |
| T5299 | 2321-2330 | VBG | denotes | including |
| T5298 | 2319-2320 | , | denotes | , |
| T5297 | 2309-2319 | NNS | denotes | components |
| T5296 | 2300-2308 | VB | denotes | effector |
| T5295 | 2297-2299 | TO | denotes | to |
| T5294 | 2292-2296 | VB | denotes | rise |
| T5293 | 2287-2291 | VBP | denotes | give |
| T5292 | 2282-2286 | PRP | denotes | they |
| T5291 | 2278-2281 | CC | denotes | and |
| T5290 | 2276-2277 | , | denotes | , |
| T5289 | 2265-2276 | NN | denotes | destruction |
| T5288 | 2259-2264 | JJ | denotes | joint |
| T5287 | 2255-2258 | CC | denotes | and |
| T5286 | 2242-2254 | NN | denotes | inflammation |
| T5285 | 2234-2241 | JJ | denotes | chronic |
| T5284 | 2231-2233 | IN | denotes | of |
| T5283 | 2223-2230 | NN | denotes | process |
| T5282 | 2219-2222 | DT | denotes | the |
| T5281 | 2216-2218 | IN | denotes | in |
| T5280 | 2208-2215 | JJ | denotes | crucial |
| T5279 | 2204-2207 | VBP | denotes | are |
| T5278 | 2202-2203 | , | denotes | , |
| T5277 | 2194-2202 | NNS | denotes | products |
| T5276 | 2183-2193 | NN | denotes | macrophage |
| T5275 | 2177-2182 | JJ | denotes | major |
| T5274 | 2173-2176 | CD | denotes | two |
| T5273 | 2171-2172 | , | denotes | , |
| T5272 | 2167-2171 | NNP | denotes | IL-1 |
| T5271 | 2163-2166 | CC | denotes | and |
| T5270 | 2161-2162 | -RRB- | denotes | ) |
| T5269 | 2156-2161 | NNP | denotes | TNF-α |
| T5268 | 2155-2156 | -LRB- | denotes | ( |
| T5267 | 2149-2154 | NN | denotes | alpha |
| T5266 | 2142-2148 | NN | denotes | factor |
| T5265 | 2133-2141 | NN | denotes | necrosis |
| T5264 | 2127-2132 | NN | denotes | Tumor |
| T5263 | 2125-2126 | . | denotes | . |
| T5262 | 2116-2125 | NNS | denotes | cytokines |
| T5261 | 2100-2115 | JJ | denotes | proinflammatory |
| T5260 | 2097-2099 | IN | denotes | of |
| T5259 | 2090-2096 | NN | denotes | source |
| T5258 | 2080-2089 | JJ | denotes | important |
| T5257 | 2077-2079 | DT | denotes | an |
| T5256 | 2073-2076 | VBP | denotes | are |
| T5255 | 2061-2072 | NNS | denotes | fibroblasts |
| T5254 | 2052-2060 | JJ | denotes | synovial |
| T5253 | 2048-2051 | CC | denotes | and |
| T5252 | 2036-2047 | NNS | denotes | macrophages |
| T5251 | 2032-2035 | CC | denotes | and |
| T5250 | 2030-2031 | , | denotes | , |
| T5249 | 2025-2030 | NN | denotes | joint |
| T5248 | 2016-2024 | JJ | denotes | inflamed |
| T5247 | 2012-2015 | DT | denotes | the |
| T5246 | 2009-2011 | IN | denotes | in |
| T5245 | 1996-2008 | VBN | denotes | overproduced |
| T5244 | 1992-1995 | VBP | denotes | are |
| T5243 | 1982-1991 | NNS | denotes | cytokines |
| T5242 | 1973-1981 | JJ | denotes | Numerous |
| T5241 | 1971-1972 | . | denotes | . |
| T5240 | 1966-1971 | NNS | denotes | cells |
| T5239 | 1950-1965 | JJ | denotes | fibroblast-like |
| T5238 | 1941-1949 | JJ | denotes | synovial |
| T5237 | 1938-1940 | IN | denotes | of |
| T5236 | 1924-1937 | NN | denotes | proliferation |
| T5235 | 1919-1923 | IN | denotes | with |
| T5234 | 1910-1918 | RB | denotes | together |
| T5233 | 1908-1909 | , | denotes | , |
| T5232 | 1903-1908 | NNS | denotes | cells |
| T5231 | 1893-1902 | JJ | denotes | dendritic |
| T5230 | 1889-1892 | CC | denotes | and |
| T5229 | 1887-1888 | , | denotes | , |
| T5228 | 1876-1887 | NNS | denotes | macrophages |
| T5227 | 1874-1875 | , | denotes | , |
| T5226 | 1863-1874 | NNS | denotes | lymphocytes |
| T5225 | 1860-1862 | IN | denotes | as |
| T5224 | 1855-1859 | JJ | denotes | such |
| T5223 | 1853-1854 | , | denotes | , |
| T5222 | 1848-1853 | NNS | denotes | cells |
| T5221 | 1835-1847 | JJ | denotes | inflammatory |
| T5220 | 1832-1834 | IN | denotes | of |
| T5219 | 1824-1831 | NN | denotes | variety |
| T5218 | 1822-1823 | DT | denotes | a |
| T5217 | 1819-1821 | IN | denotes | of |
| T5216 | 1808-1818 | VB | denotes | infiltrate |
| T5215 | 1805-1807 | DT | denotes | an |
| T5214 | 1802-1804 | IN | denotes | by |
| T5213 | 1788-1801 | VBN | denotes | characterized |
| T5212 | 1785-1787 | VBZ | denotes | is |
| T5211 | 1783-1784 | -RRB- | denotes | ) |
| T5210 | 1781-1783 | NNP | denotes | RA |
| T5209 | 1780-1781 | -LRB- | denotes | ( |
| T5208 | 1770-1779 | NNS | denotes | arthritis |
| T5207 | 1759-1769 | JJ | denotes | rheumatoid |
| T5206 | 1756-1758 | IN | denotes | of |
| T5205 | 1747-1755 | NN | denotes | membrane |
| T5204 | 1738-1746 | JJ | denotes | synovial |
| T5203 | 1734-1737 | DT | denotes | The |
| T5202 | 1732-1733 | . | denotes | . |
| T5201 | 1731-1732 | NNP | denotes | ] |
| T5824 | 5329-5330 | . | denotes | . |
| T5823 | 5321-5329 | NNS | denotes | patients |
| T5822 | 5318-5320 | NNP | denotes | RA |
| T5821 | 5313-5317 | IN | denotes | from |
| T5820 | 5307-5312 | NNS | denotes | cells |
| T5819 | 5305-5306 | NNP | denotes | T |
| T5818 | 5303-5304 | CD | denotes | + |
| T5817 | 5300-5303 | NNP | denotes | CD4 |
| T5816 | 5298-5299 | -RRB- | denotes | ) |
| T5815 | 5296-5298 | NNP | denotes | PB |
| T5814 | 5295-5296 | -LRB- | denotes | ( |
| T5813 | 5289-5294 | NN | denotes | blood |
| T5812 | 5278-5288 | JJ | denotes | peripheral |
| T5811 | 5275-5277 | IN | denotes | in |
| T5810 | 5270-5274 | NNP | denotes | mRNA |
| T5809 | 5264-5269 | CD | denotes | SOCS3 |
| T5808 | 5260-5263 | CC | denotes | and |
| T5807 | 5254-5259 | CD | denotes | SOCS1 |
| T5806 | 5251-5253 | IN | denotes | of |
| T5805 | 5240-5250 | NN | denotes | expression |
| T5804 | 5236-5239 | DT | denotes | the |
| T5803 | 5232-5235 | CC | denotes | and |
| T5802 | 5230-5231 | , | denotes | , |
| T5801 | 5225-5230 | NNP | denotes | IL-10 |
| T5800 | 5222-5224 | IN | denotes | by |
| T5799 | 5206-5221 | NN | denotes | phosphorylation |
| T5798 | 5200-5205 | CD | denotes | STAT3 |
| T5797 | 5196-5199 | CC | denotes | and |
| T5796 | 5190-5195 | CD | denotes | STAT1 |
| T5795 | 5187-5189 | IN | denotes | of |
| T5794 | 5177-5186 | NN | denotes | induction |
| T5793 | 5173-5176 | DT | denotes | the |
| T5792 | 5171-5172 | , | denotes | , |
| T5791 | 5166-5171 | NNP | denotes | IL-10 |
| T5790 | 5163-5165 | IN | denotes | of |
| T5789 | 5154-5162 | NN | denotes | presence |
| T5788 | 5150-5153 | DT | denotes | the |
| T5787 | 5147-5149 | IN | denotes | in |
| T5786 | 5133-5146 | NN | denotes | costimulation |
| T5785 | 5128-5132 | NNP | denotes | CD28 |
| T5784 | 5124-5127 | CC | denotes | and |
| T5783 | 5120-5123 | NNP | denotes | CD3 |
| T5782 | 5114-5119 | IN | denotes | after |
| T5781 | 5108-5113 | NNP | denotes | IFN-γ |
| T5780 | 5105-5107 | IN | denotes | of |
| T5779 | 5094-5104 | NN | denotes | production |
| T5778 | 5090-5093 | DT | denotes | the |
| T5777 | 5077-5089 | VBD | denotes | investigated |
| T5776 | 5074-5076 | PRP | denotes | we |
| T5775 | 5072-5073 | , | denotes | , |
| T5774 | 5070-5072 | NNP | denotes | RA |
| T5773 | 5067-5069 | IN | denotes | in |
| T5772 | 5056-5066 | NN | denotes | inhibition |
| T5771 | 5049-5055 | JJ | denotes | direct |
| T5770 | 5044-5048 | DT | denotes | this |
| T5769 | 5041-5043 | TO | denotes | to |
| T5768 | 5035-5040 | NNS | denotes | cells |
| T5767 | 5033-5034 | NNP | denotes | T |
| T5766 | 5031-5032 | CD | denotes | + |
| T5765 | 5028-5031 | CD | denotes | CD4 |
| T5764 | 5025-5027 | IN | denotes | of |
| T5763 | 5014-5024 | NN | denotes | resistance |
| T5762 | 5010-5013 | DT | denotes | the |
| T5761 | 5000-5009 | VB | denotes | elucidate |
| T5760 | 4997-4999 | TO | denotes | To |
| T5759 | 4995-4996 | . | denotes | . |
| T5758 | 4990-4995 | NNS | denotes | cells |
| T5757 | 4971-4989 | JJ | denotes | antigen-presenting |
| T5756 | 4968-4970 | IN | denotes | of |
| T5755 | 4959-4967 | NN | denotes | function |
| T5754 | 4955-4958 | DT | denotes | the |
| T5753 | 4940-4954 | VBG | denotes | downregulating |
| T5752 | 4937-4939 | IN | denotes | by |
| T5751 | 4926-4936 | RB | denotes | indirectly |
| T5750 | 4923-4925 | IN | denotes | as |
| T5749 | 4918-4922 | RB | denotes | well |
| T5748 | 4915-4917 | RB | denotes | as |
| T5747 | 4913-4914 | , | denotes | , |
| T5746 | 4912-4913 | NNP | denotes | ] |
| T5745 | 4910-4912 | CD | denotes | 24 |
| T5744 | 4909-4910 | NNP | denotes | [ |
| T5743 | 4901-4908 | NN | denotes | pathway |
| T5742 | 4891-4900 | VBG | denotes | signaling |
| T5741 | 4886-4890 | NNP | denotes | CD28 |
| T5740 | 4882-4885 | DT | denotes | the |
| T5739 | 4871-4881 | VBG | denotes | inhibiting |
| T5738 | 4868-4870 | IN | denotes | by |
| T5737 | 4859-4867 | NN | denotes | response |
| T5736 | 4850-4858 | NN | denotes | cytokine |
| T5735 | 4843-4849 | NN | denotes | T-cell |
| T5734 | 4826-4842 | JJ | denotes | antigen-specific |
| T5733 | 4822-4825 | DT | denotes | the |
| T5732 | 4815-4821 | VBZ | denotes | blocks |
| T5731 | 4803-4814 | RB | denotes | efficiently |
| T5730 | 4797-4802 | NN | denotes | IL-10 |
| T5200 | 1728-1731 | CD | denotes | 8,9 |
| T5199 | 1727-1728 | NNP | denotes | [ |
| T5198 | 1721-1726 | NNP | denotes | IL-10 |
| T5197 | 1718-1720 | IN | denotes | by |
| T5196 | 1710-1717 | VBN | denotes | induced |
| T5195 | 1705-1709 | IN | denotes | that |
| T5194 | 1701-1704 | RB | denotes | not |
| T5193 | 1697-1700 | CC | denotes | but |
| T5192 | 1692-1696 | NN | denotes | IL-6 |
| T5191 | 1689-1691 | IN | denotes | by |
| T5190 | 1681-1688 | VBN | denotes | induced |
| T5189 | 1670-1680 | NN | denotes | activation |
| T5188 | 1664-1669 | CD | denotes | STAT3 |
| T5187 | 1655-1663 | VBG | denotes | blocking |
| T5186 | 1642-1654 | RB | denotes | specifically |
| T5185 | 1639-1641 | IN | denotes | by |
| T5184 | 1637-1638 | , | denotes | , |
| T5183 | 1633-1637 | NNP | denotes | IL-6 |
| T5182 | 1629-1632 | CC | denotes | and |
| T5181 | 1623-1628 | NNP | denotes | IL-10 |
| T5180 | 1620-1622 | IN | denotes | of |
| T5179 | 1613-1619 | NN | denotes | action |
| T5178 | 1603-1612 | JJ | denotes | divergent |
| T5177 | 1599-1602 | DT | denotes | the |
| T5176 | 1588-1598 | VBG | denotes | regulating |
| T5175 | 1585-1587 | IN | denotes | in |
| T5174 | 1580-1584 | NN | denotes | role |
| T5173 | 1576-1579 | JJ | denotes | key |
| T5172 | 1574-1575 | DT | denotes | a |
| T5171 | 1568-1573 | VBZ | denotes | plays |
| T5170 | 1562-1567 | CD | denotes | SOCS3 |
| T5169 | 1557-1561 | IN | denotes | that |
| T5101 | 1161-1164 | CC | denotes | but |
| T5100 | 1159-1160 | , | denotes | , |
| T5099 | 1158-1159 | NNP | denotes | ] |
| T5098 | 1157-1158 | CD | denotes | 5 |
| T5097 | 1156-1157 | VBP | denotes | [ |
| T5096 | 1144-1155 | NNS | denotes | neutrophils |
| T5095 | 1140-1143 | CC | denotes | and |
| T5094 | 1128-1139 | NNS | denotes | macrophages |
| T5093 | 1125-1127 | IN | denotes | in |
| T5092 | 1115-1124 | NNS | denotes | reactions |
| T5091 | 1097-1114 | JJ | denotes | anti-inflammatory |
| T5090 | 1082-1096 | JJ | denotes | IL-10-mediated |
| T5089 | 1078-1081 | IN | denotes | for |
| T5088 | 1068-1077 | JJ | denotes | essential |
| T5087 | 1065-1067 | VBZ | denotes | is |
| T5086 | 1054-1064 | NN | denotes | activation |
| T5085 | 1048-1053 | CD | denotes | STAT3 |
| T5084 | 1043-1047 | IN | denotes | that |
| T5083 | 1037-1042 | VBN | denotes | shown |
| T5082 | 1032-1036 | VBP | denotes | have |
| T5081 | 1027-1031 | NNS | denotes | mice |
| T5080 | 1011-1026 | JJ | denotes | STAT3-deficient |
| T5079 | 992-1010 | JJ | denotes | cell-type-specific |
| T5078 | 989-991 | IN | denotes | of |
| T5077 | 981-988 | NNS | denotes | Studies |
| T5076 | 979-980 | . | denotes | . |
| T5075 | 978-979 | NNP | denotes | ] |
| T5074 | 977-978 | CD | denotes | 4 |
| T5073 | 976-977 | VBP | denotes | [ |
| T5072 | 966-975 | NNS | denotes | responses |
| T5071 | 950-965 | JJ | denotes | proinflammatory |
| T5070 | 937-949 | JJ | denotes | IL-6-derived |
| T5069 | 933-936 | CC | denotes | and |
| T5068 | 915-932 | JJ | denotes | anti-inflammatory |
| T5067 | 901-914 | JJ | denotes | IL-10-derived |
| T5066 | 896-900 | DT | denotes | both |
| T5065 | 892-895 | IN | denotes | for |
| T5064 | 878-891 | JJ | denotes | indispensable |
| T5063 | 875-877 | VBZ | denotes | is |
| T5062 | 869-874 | NNP | denotes | STAT3 |
| T5061 | 867-868 | , | denotes | , |
| T5060 | 855-867 | RB | denotes | Intriguingly |
| T5059 | 853-854 | . | denotes | . |
| T5058 | 840-853 | NN | denotes | transcription |
| T5057 | 835-839 | NN | denotes | gene |
| T5056 | 826-834 | VB | denotes | modulate |
| T5055 | 822-825 | CC | denotes | and |
| T5054 | 820-821 | , | denotes | , |
| T5053 | 813-820 | NN | denotes | nucleus |
| T5052 | 809-812 | DT | denotes | the |
| T5051 | 804-808 | IN | denotes | into |
| T5050 | 792-803 | VBP | denotes | translocate |
| T5049 | 784-791 | RB | denotes | rapidly |
| T5048 | 782-783 | , | denotes | , |
| T5047 | 770-782 | NNS | denotes | heterodimers |
| T5046 | 767-769 | CC | denotes | or |
| T5045 | 756-766 | NNS | denotes | homodimers |
| T5044 | 751-755 | VBP | denotes | form |
| T5043 | 742-750 | NNS | denotes | proteins |
| T5042 | 736-741 | NNP | denotes | STAT3 |
| T5041 | 732-735 | CC | denotes | and |
| T5040 | 726-731 | NNP | denotes | STAT1 |
| T5039 | 724-725 | , | denotes | , |
| T5038 | 709-724 | NN | denotes | phosphorylation |
| T5037 | 704-708 | IN | denotes | Upon |
| T5036 | 702-703 | . | denotes | . |
| T5035 | 701-702 | NNP | denotes | ] |
| T5034 | 700-701 | CD | denotes | 3 |
| T5033 | 699-700 | NN | denotes | [ |
| T5032 | 693-698 | CD | denotes | STAT1 |
| T5031 | 689-692 | CC | denotes | and |
| T5030 | 687-688 | CD | denotes | 3 |
| T5029 | 685-686 | -RRB- | denotes | ) |
| T5028 | 681-685 | NNP | denotes | STAT |
| T5027 | 680-681 | -LRB- | denotes | ( |
| T5026 | 666-679 | NN | denotes | transcription |
| T5025 | 663-665 | IN | denotes | of |
| T5024 | 653-662 | NN | denotes | activator |
| T5023 | 649-652 | CC | denotes | and |
| T5022 | 638-648 | NN | denotes | transducer |
| T5021 | 631-637 | VBP | denotes | signal |
| T5020 | 623-630 | NNS | denotes | factors |
| T5019 | 607-622 | JJ | denotes | transcriptional |
| T5018 | 600-606 | NN | denotes | latent |
| T5017 | 596-599 | DT | denotes | the |
| T5016 | 593-595 | IN | denotes | of |
| T5015 | 582-592 | NN | denotes | activation |
| T5014 | 578-581 | CC | denotes | and |
| T5013 | 562-577 | NN | denotes | phosphorylation |
| T5012 | 553-561 | JJ | denotes | tyrosine |
| T5011 | 545-552 | VBZ | denotes | induces |
| T5010 | 539-544 | NN | denotes | IL-10 |
| T5009 | 537-538 | . | denotes | . |
| T5008 | 536-537 | NN | denotes | ] |
| T5007 | 535-536 | CD | denotes | 2 |
| T5006 | 534-535 | JJ | denotes | [ |
| T5005 | 521-533 | RB | denotes | respectively |
| T5004 | 519-520 | , | denotes | , |
| T5003 | 513-519 | NN | denotes | IL-10R |
| T5002 | 511-512 | CD | denotes | 2 |
| T5001 | 506-510 | NN | denotes | type |
| T5000 | 502-505 | CC | denotes | and |
| T4999 | 494-501 | NNP | denotes | IL-10R1 |
| T4998 | 489-493 | IN | denotes | with |
| T4997 | 478-488 | VBN | denotes | associated |
| T4996 | 463-477 | RB | denotes | constitutively |
| T4995 | 459-462 | VBP | denotes | are |
| T4994 | 453-458 | WDT | denotes | which |
| T4993 | 451-452 | , | denotes | , |
| T4992 | 447-451 | NNP | denotes | Tyk2 |
| T4991 | 443-446 | CC | denotes | and |
| T4990 | 438-442 | NNP | denotes | Jak1 |
| T4989 | 430-437 | VBZ | denotes | kinases |
| T4988 | 421-429 | NN | denotes | tyrosine |
| T4987 | 414-420 | NN | denotes | family |
| T4986 | 412-413 | -RRB- | denotes | ) |
| T4985 | 409-412 | NNP | denotes | JAK |
| T4984 | 408-409 | -LRB- | denotes | ( |
| T4983 | 401-407 | NN | denotes | kinase |
| T4982 | 395-400 | NNP | denotes | Janus |
| T4981 | 391-394 | DT | denotes | the |
| T4980 | 383-390 | VBZ | denotes | engages |
| T4979 | 376-382 | NNP | denotes | IL-10R |
| T4978 | 372-375 | CC | denotes | and |
| T4977 | 366-371 | NNP | denotes | IL-10 |
| T4976 | 363-365 | IN | denotes | of |
| T4975 | 351-362 | NN | denotes | interaction |
| T4974 | 347-350 | DT | denotes | The |
| T4973 | 345-346 | . | denotes | . |
| T4972 | 344-345 | NNP | denotes | ] |
| T4971 | 343-344 | CD | denotes | 1 |
| T4970 | 342-343 | NNP | denotes | [ |
| T4969 | 335-341 | NNP | denotes | IL-10R |
| T4968 | 333-334 | CD | denotes | 2 |
| T4967 | 328-332 | NN | denotes | type |
| T4966 | 318-327 | NN | denotes | component |
| T4965 | 308-317 | JJ | denotes | accessory |
| T4964 | 304-307 | DT | denotes | the |
| T4963 | 300-303 | CC | denotes | and |
| T4962 | 298-299 | -RRB- | denotes | ) |
| T4961 | 291-298 | NN | denotes | IL-10R1 |
| T4960 | 290-291 | -LRB- | denotes | ( |
| T4959 | 283-289 | NN | denotes | IL-10R |
| T4958 | 281-282 | CD | denotes | 1 |
| T4957 | 276-280 | NN | denotes | type |
| T4956 | 266-275 | NN | denotes | component |
| T4955 | 251-265 | JJ | denotes | ligand-binding |
| T4954 | 243-250 | JJ | denotes | primary |
| T4953 | 239-242 | DT | denotes | the |
| T4952 | 237-238 | , | denotes | , |
| T4951 | 229-237 | NNS | denotes | subunits |
| T4950 | 225-228 | CD | denotes | two |
| T4949 | 222-224 | IN | denotes | of |
| T4948 | 213-221 | VBN | denotes | composed |
| T4947 | 210-212 | VBZ | denotes | is |
| T4946 | 205-209 | WDT | denotes | that |
| T4945 | 197-204 | NN | denotes | complex |
| T4944 | 195-196 | -RRB- | denotes | ) |
| T4943 | 189-195 | NN | denotes | IL-10R |
| T4942 | 188-189 | -LRB- | denotes | ( |
| T4941 | 179-187 | NN | denotes | receptor |
| T4940 | 173-178 | NN | denotes | IL-10 |
| T4939 | 169-172 | DT | denotes | the |
| T4938 | 166-168 | TO | denotes | to |
| T4937 | 160-165 | NNS | denotes | binds |
| T4936 | 154-159 | JJ | denotes | IL-10 |
| T4935 | 152-153 | . | denotes | . |
| T4934 | 143-152 | NNS | denotes | cytokines |
| T4933 | 127-142 | JJ | denotes | proinflammatory |
| T4932 | 124-126 | IN | denotes | of |
| T4931 | 115-123 | NN | denotes | function |
| T4930 | 111-114 | CC | denotes | and |
| T4929 | 100-110 | NN | denotes | production |
| T4928 | 96-99 | DT | denotes | the |
| T4927 | 85-95 | VBG | denotes | inhibiting |
| T4926 | 82-84 | IN | denotes | by |
| T4925 | 75-81 | RB | denotes | mainly |
| T4924 | 73-74 | , | denotes | , |
| T4923 | 64-73 | NNS | denotes | responses |
| T4922 | 51-63 | JJ | denotes | inflammatory |
| T4921 | 40-50 | VBG | denotes | regulating |
| T4920 | 37-39 | IN | denotes | in |
| T4919 | 28-36 | NN | denotes | cytokine |
| T4918 | 24-27 | JJ | denotes | key |
| T5505 | 3556-3557 | NNP | denotes | T |
| T5504 | 3554-3555 | CD | denotes | + |
| T5503 | 3551-3554 | CD | denotes | CD4 |
| T5502 | 3549-3550 | . | denotes | . |
| T5501 | 3548-3549 | NNP | denotes | ] |
| T5500 | 3546-3548 | CD | denotes | 15 |
| T5499 | 3545-3546 | NNP | denotes | [ |
| T5498 | 3538-3544 | NN | denotes | factor |
| T5497 | 3519-3537 | JJ | denotes | colony-stimulating |
| T5496 | 3508-3518 | NN | denotes | macrophage |
| T5495 | 3496-3507 | NN | denotes | granulocyte |
| T5494 | 3492-3495 | CC | denotes | and |
| T5493 | 3490-3491 | , | denotes | , |
| T5492 | 3486-3490 | NNP | denotes | IL-1 |
| T5491 | 3484-3485 | , | denotes | , |
| T5490 | 3479-3484 | NNP | denotes | TNF-α |
| T5489 | 3476-3478 | IN | denotes | of |
| T5488 | 3467-3475 | NN | denotes | presence |
| T5487 | 3463-3466 | DT | denotes | the |
| T5486 | 3460-3462 | TO | denotes | to |
| T5485 | 3456-3459 | JJ | denotes | due |
| T5484 | 3450-3455 | NNS | denotes | cells |
| T5483 | 3440-3449 | JJ | denotes | dendritic |
| T5482 | 3434-3439 | NN | denotes | fluid |
| T5481 | 3425-3433 | JJ | denotes | synovial |
| T5480 | 3422-3424 | IN | denotes | in |
| T5479 | 3412-3421 | VBN | denotes | decreased |
| T5478 | 3409-3411 | VBZ | denotes | is |
| T5477 | 3401-3408 | NN | denotes | IL-10R1 |
| T5476 | 3398-3400 | IN | denotes | of |
| T5475 | 3387-3397 | NN | denotes | expression |
| T5474 | 3379-3386 | NN | denotes | surface |
| T5473 | 3374-3378 | NN | denotes | Cell |
| T5472 | 3372-3373 | . | denotes | . |
| T5471 | 3371-3372 | NNP | denotes | ] |
| T5470 | 3366-3371 | CD | denotes | 13,14 |
| T5469 | 3365-3366 | NNP | denotes | [ |
| T5468 | 3355-3364 | NNS | denotes | complexes |
| T5467 | 3348-3354 | JJ | denotes | immune |
| T5466 | 3344-3347 | CC | denotes | and |
| T5465 | 3339-3343 | NNP | denotes | IL-1 |
| T5464 | 3335-3338 | CC | denotes | and |
| T5463 | 3329-3334 | NNP | denotes | TNF-α |
| T5462 | 3326-3328 | IN | denotes | as |
| T5461 | 3321-3325 | JJ | denotes | such |
| T5460 | 3311-3320 | NNS | denotes | cytokines |
| T5459 | 3295-3310 | JJ | denotes | proinflammatory |
| T5458 | 3292-3294 | TO | denotes | to |
| T5457 | 3283-3291 | NN | denotes | exposure |
| T5456 | 3275-3282 | JJ | denotes | chronic |
| T5455 | 3270-3274 | IN | denotes | upon |
| T5454 | 3258-3269 | NNS | denotes | macrophages |
| T5453 | 3255-3257 | IN | denotes | in |
| T5452 | 3246-3254 | VBN | denotes | impaired |
| T5451 | 3243-3245 | VBZ | denotes | is |
| T5450 | 3233-3242 | VBG | denotes | signaling |
| T5449 | 3227-3232 | NN | denotes | IL-10 |
| T5448 | 3225-3226 | . | denotes | . |
| T5447 | 3213-3225 | NN | denotes | inflammation |
| T5446 | 3205-3212 | JJ | denotes | chronic |
| T5445 | 3198-3204 | IN | denotes | during |
| T5444 | 3185-3197 | NN | denotes | transduction |
| T5443 | 3178-3184 | NN | denotes | signal |
| T5442 | 3175-3177 | IN | denotes | of |
| T5404 | 2954-2957 | IN | denotes | for |
| T5403 | 2944-2953 | NN | denotes | regulator |
| T5402 | 2935-2943 | JJ | denotes | negative |
| T5401 | 2933-2934 | DT | denotes | a |
| T5400 | 2930-2932 | IN | denotes | as |
| T5399 | 2924-2929 | VBN | denotes | known |
| T5398 | 2919-2923 | RB | denotes | best |
| T5397 | 2916-2918 | VBZ | denotes | is |
| T5396 | 2914-2915 | , | denotes | , |
| T5395 | 2913-2914 | -RRB- | denotes | ) |
| T5394 | 2911-2913 | NNP | denotes | ST |
| T5393 | 2910-2911 | -LRB- | denotes | ( |
| T5392 | 2903-2909 | NN | denotes | tissue |
| T5391 | 2894-2902 | JJ | denotes | synovial |
| T5390 | 2890-2893 | DT | denotes | the |
| T5389 | 2887-2889 | IN | denotes | in |
| T5388 | 2881-2886 | NNS | denotes | cells |
| T5387 | 2879-2880 | NNP | denotes | T |
| T5386 | 2876-2878 | IN | denotes | by |
| T4917 | 22-23 | DT | denotes | a |
| T4916 | 19-21 | VBZ | denotes | is |
| T4915 | 13-18 | NN | denotes | IL-10 |
| T5168 | 1548-1556 | VBP | denotes | indicate |
| T5167 | 1540-1547 | NNS | denotes | studies |
| T5166 | 1533-1539 | JJ | denotes | Recent |
| T5165 | 1531-1532 | . | denotes | . |
| T5164 | 1530-1531 | NNP | denotes | ] |
| T5163 | 1529-1530 | CD | denotes | 7 |
| T5162 | 1528-1529 | NNP | denotes | [ |
| T5161 | 1518-1527 | VBN | denotes | clarified |
| T5160 | 1513-1517 | VBN | denotes | been |
| T5159 | 1508-1512 | VBP | denotes | have |
| T5158 | 1499-1507 | NNS | denotes | pathways |
| T5157 | 1489-1498 | VBG | denotes | signaling |
| T5156 | 1480-1488 | NN | denotes | cytokine |
| T5155 | 1471-1479 | VBG | denotes | opposing |
| T5154 | 1468-1470 | IN | denotes | by |
| T5153 | 1457-1467 | NN | denotes | inhibition |
| T5152 | 1447-1456 | NN | denotes | crosstalk |
| T5151 | 1444-1446 | IN | denotes | of |
| T5150 | 1434-1443 | NNS | denotes | mediators |
| T5149 | 1430-1433 | DT | denotes | the |
| T5148 | 1427-1429 | IN | denotes | as |
| T5147 | 1421-1426 | NNS | denotes | roles |
| T5146 | 1415-1420 | PRP$ | denotes | their |
| T5145 | 1411-1414 | CC | denotes | but |
| T5144 | 1409-1410 | , | denotes | , |
| T5143 | 1404-1409 | NNS | denotes | loops |
| T5142 | 1393-1403 | NN | denotes | inhibition |
| T5141 | 1384-1392 | NN | denotes | feedback |
| T5140 | 1376-1383 | JJ | denotes | classic |
| T5139 | 1373-1375 | IN | denotes | in |
| T5138 | 1369-1372 | VB | denotes | act |
| T5137 | 1365-1368 | MD | denotes | can |
| T5136 | 1360-1364 | WDT | denotes | that |
| T5135 | 1349-1359 | NNS | denotes | inhibitors |
| T5134 | 1342-1348 | NN | denotes | kinase |
| T5133 | 1338-1341 | NNP | denotes | JAK |
| T5132 | 1327-1337 | JJ | denotes | endogenous |
| T5131 | 1324-1326 | IN | denotes | of |
| T5130 | 1317-1323 | NN | denotes | family |
| T5129 | 1315-1316 | DT | denotes | a |
| T5128 | 1312-1314 | IN | denotes | as |
| T5127 | 1301-1311 | VBN | denotes | identified |
| T5126 | 1296-1300 | VBN | denotes | been |
| T5125 | 1291-1295 | VBP | denotes | have |
| T5124 | 1282-1290 | NNS | denotes | proteins |
| T5123 | 1280-1281 | -RRB- | denotes | ) |
| T5122 | 1276-1280 | NNP | denotes | SOCS |
| T5121 | 1275-1276 | -LRB- | denotes | ( |
| T5120 | 1265-1274 | VBG | denotes | signaling |
| T5119 | 1256-1264 | NN | denotes | cytokine |
| T5118 | 1253-1255 | IN | denotes | of |
| T5117 | 1242-1252 | NN | denotes | suppressor |
| T5116 | 1238-1241 | DT | denotes | The |
| T5115 | 1236-1237 | . | denotes | . |
| T5114 | 1235-1236 | NNP | denotes | ] |
| T5113 | 1234-1235 | CD | denotes | 6 |
| T5112 | 1233-1234 | NNP | denotes | [ |
| T5111 | 1227-1232 | NNS | denotes | cells |
| T5110 | 1225-1226 | NNP | denotes | T |
| T5109 | 1222-1224 | IN | denotes | in |
| T5108 | 1212-1221 | NN | denotes | apoptosis |
| T5107 | 1209-1211 | IN | denotes | of |
| T5106 | 1198-1208 | NN | denotes | prevention |
| T5105 | 1184-1197 | JJ | denotes | IL-6-mediated |
| T5104 | 1180-1183 | IN | denotes | for |
| T5103 | 1168-1179 | JJ | denotes | responsible |
| T5102 | 1165-1167 | VBZ | denotes | is |
| T5405 | 2958-2968 | NN | denotes | macrophage |
| T5345 | 2619-2629 | NN | denotes | maturation |
| T5344 | 2612-2618 | NNP | denotes | B-cell |
| T5343 | 2610-2611 | , | denotes | , |
| T5342 | 2602-2610 | NN | denotes | response |
| T5341 | 2590-2601 | JJ | denotes | acute-phase |
| T5340 | 2586-2589 | DT | denotes | the |
| T5339 | 2575-2585 | VBG | denotes | simulating |
| T5338 | 2567-2574 | VBP | denotes | include |
| T5337 | 2559-2566 | NNS | denotes | actions |
| T5336 | 2543-2558 | JJ | denotes | proinflammatory |
| T5335 | 2539-2542 | PRP$ | denotes | its |
| T5334 | 2535-2538 | CC | denotes | and |
| T5333 | 2533-2534 | , | denotes | , |
| T5332 | 2522-2533 | NNS | denotes | fibroblasts |
| T5331 | 2512-2521 | VBN | denotes | activated |
| T5330 | 2509-2511 | IN | denotes | by |
| T5329 | 2495-2508 | RB | denotes | substantially |
| T5328 | 2486-2494 | VBD | denotes | produced |
| T5327 | 2477-2485 | NN | denotes | cytokine |
| T5326 | 2465-2476 | JJ | denotes | pleiotropic |
| T5325 | 2463-2464 | DT | denotes | a |
| T5324 | 2460-2462 | VBZ | denotes | is |
| T5323 | 2455-2459 | NN | denotes | IL-6 |
| T5322 | 2453-2454 | . | denotes | . |
| T5321 | 2452-2453 | NNP | denotes | ] |
| T5320 | 2450-2452 | CD | denotes | 10 |
| T5319 | 2449-2450 | NNP | denotes | [ |
| T5318 | 2441-2448 | NNS | denotes | species |
| T5317 | 2434-2440 | NN | denotes | oxygen |
| T5316 | 2425-2433 | JJ | denotes | reactive |
| T5315 | 2421-2424 | CC | denotes | and |
| T5314 | 2419-2420 | , | denotes | , |
| T5313 | 2414-2419 | NN | denotes | oxide |
| T5312 | 2407-2413 | JJ | denotes | nitric |
| T5311 | 2405-2406 | , | denotes | , |
| T5384 | 2865-2868 | CC | denotes | and |
| T5383 | 2853-2864 | NNS | denotes | macrophages |
| T5382 | 2850-2852 | IN | denotes | by |
| T5381 | 2841-2849 | VBN | denotes | produced |
| T5380 | 2839-2840 | , | denotes | , |
| T5379 | 2834-2839 | NN | denotes | IL-10 |
| T5378 | 2832-2833 | . | denotes | . |
| T5377 | 2826-2832 | NNS | denotes | joints |
| T5376 | 2823-2825 | NNP | denotes | RA |
| T5375 | 2820-2822 | IN | denotes | in |
| T5374 | 2809-2819 | NNS | denotes | quantities |
| T5373 | 2803-2808 | JJ | denotes | large |
| T5372 | 2800-2802 | IN | denotes | in |
| T5371 | 2792-2799 | JJ | denotes | present |
| T5370 | 2787-2791 | RB | denotes | also |
| T5369 | 2783-2786 | VBP | denotes | are |
| T5368 | 2772-2782 | NNS | denotes | inhibitors |
| T5367 | 2763-2771 | NN | denotes | cytokine |
| T5366 | 2759-2762 | CC | denotes | and |
| T5365 | 2749-2758 | NNS | denotes | cytokines |
| T5364 | 2731-2748 | JJ | denotes | anti-inflammatory |
| T5363 | 2729-2730 | , | denotes | , |
| T5362 | 2722-2729 | RB | denotes | However |
| T5361 | 2720-2721 | . | denotes | . |
| T5360 | 2719-2720 | NNP | denotes | ] |
| T5359 | 2717-2719 | CD | denotes | 11 |
| T5358 | 2716-2717 | NNP | denotes | [ |
| T5357 | 2700-2715 | NN | denotes | differentiation |
| T5356 | 2695-2699 | NN | denotes | cell |
| T5355 | 2685-2694 | NN | denotes | precursor |
| T5354 | 2671-2684 | JJ | denotes | hematopoietic |
| T5353 | 2667-2670 | CC | denotes | and |
| T5352 | 2665-2666 | , | denotes | , |
| T5351 | 2656-2665 | NNS | denotes | functions |
| T5350 | 2649-2655 | NNP | denotes | T-cell |
| T5349 | 2647-2648 | , | denotes | , |
| T5348 | 2642-2647 | NNS | denotes | cells |
| T5347 | 2635-2641 | NN | denotes | plasma |
| T5346 | 2630-2634 | IN | denotes | into |
| T5385 | 2869-2875 | RB | denotes | partly |
| T5441 | 3169-3174 | NN | denotes | level |
| T5440 | 3165-3168 | DT | denotes | the |
| T5439 | 3162-3164 | IN | denotes | at |
| T5438 | 3152-3161 | VBN | denotes | modulated |
| T5437 | 3149-3151 | VB | denotes | be |
| T5436 | 3146-3148 | TO | denotes | to |
| T5435 | 3138-3145 | VBZ | denotes | appears |
| T5434 | 3132-3137 | NN | denotes | IL-10 |
| T5433 | 3129-3131 | IN | denotes | of |
| T5432 | 3122-3128 | NN | denotes | action |
| T5431 | 3104-3121 | JJ | denotes | anti-inflammatory |
| T5430 | 3100-3103 | DT | denotes | the |
| T5429 | 3098-3099 | , | denotes | , |
| T5428 | 3090-3098 | NN | denotes | addition |
| T5427 | 3087-3089 | IN | denotes | In |
| T5426 | 3085-3086 | . | denotes | . |
| T5425 | 3084-3085 | NNP | denotes | ] |
| T5424 | 3082-3084 | CD | denotes | 12 |
| T5423 | 3081-3082 | NNP | denotes | [ |
| T5422 | 3074-3080 | NNS | denotes | events |
| T5421 | 3058-3073 | JJ | denotes | proinflammatory |
| T5420 | 3055-3057 | IN | denotes | of |
| T5419 | 3047-3054 | NN | denotes | cascade |
| T5418 | 3043-3046 | DT | denotes | the |
| T5417 | 3028-3042 | VB | denotes | counterbalance |
| T5416 | 3025-3027 | TO | denotes | to |
| T5415 | 3012-3024 | JJ | denotes | insufficient |
| T5414 | 3009-3011 | VBZ | denotes | is |
| T5413 | 3003-3008 | NN | denotes | level |
| T5412 | 2992-3002 | NN | denotes | expression |
| T5411 | 2988-2991 | DT | denotes | the |
| T5410 | 2984-2987 | CC | denotes | but |
| T5409 | 2982-2983 | , | denotes | , |
| T5408 | 2977-2982 | NNS | denotes | cells |
| T5407 | 2973-2976 | JJ | denotes | Th1 |
| T5406 | 2969-2972 | CC | denotes | and |
| T5513 | 3606-3607 | , | denotes | , |
| T5512 | 3598-3606 | NNS | denotes | antigens |
| T5511 | 3584-3597 | JJ | denotes | arthritogenic |
| T5510 | 3581-3583 | IN | denotes | by |
| T5509 | 3571-3580 | VBN | denotes | activated |
| T5508 | 3568-3570 | VB | denotes | be |
| T5507 | 3564-3567 | MD | denotes | may |
| T5506 | 3558-3563 | NNS | denotes | cells |
| T5632 | 4248-4263 | JJ | denotes | proinflammatory |
| T5631 | 4245-4247 | IN | denotes | of |
| T5630 | 4237-4244 | NN | denotes | release |
| T5629 | 4233-4236 | DT | denotes | the |
| T5628 | 4230-4232 | IN | denotes | as |
| T5627 | 4225-4229 | RB | denotes | well |
| T5626 | 4222-4224 | RB | denotes | as |
| T5625 | 4220-4221 | , | denotes | , |
| T5624 | 4216-4220 | NNP | denotes | CD11 |
| T5623 | 4212-4215 | CC | denotes | and |
| T5622 | 4207-4211 | NNP | denotes | CD69 |
| T5621 | 4199-4206 | NN | denotes | surface |
| T5620 | 4194-4198 | NN | denotes | cell |
| T5619 | 4191-4193 | IN | denotes | of |
| T5618 | 4185-4190 | NNS | denotes | means |
| T5617 | 4182-4184 | IN | denotes | by |
| T5616 | 4172-4181 | VBG | denotes | signaling |
| T5615 | 4164-4171 | NN | denotes | surface |
| T5614 | 4159-4163 | NN | denotes | cell |
| T5613 | 4151-4158 | IN | denotes | through |
| T5612 | 4139-4150 | NNS | denotes | fibroblasts |
| T5611 | 4130-4138 | JJ | denotes | synovial |
| T5610 | 4126-4129 | CC | denotes | and |
| T5609 | 4114-4125 | NNS | denotes | macrophages |
| T5608 | 4111-4113 | IN | denotes | of |
| T5607 | 4100-4110 | NN | denotes | activation |
| T5606 | 4096-4099 | DT | denotes | the |
| T5605 | 4085-4095 | VBG | denotes | sustaining |
| T5604 | 4082-4084 | IN | denotes | in |
| T5660 | 4379-4389 | NN | denotes | production |
| T5659 | 4372-4378 | JJ | denotes | B-cell |
| T5658 | 4362-4371 | VB | denotes | stimulate |
| T5657 | 4356-4361 | MD | denotes | could |
| T5656 | 4350-4355 | NNS | denotes | cells |
| T5655 | 4348-4349 | NNP | denotes | T |
| T5654 | 4346-4347 | NNP | denotes | + |
| T5653 | 4343-4346 | NNP | denotes | CD4 |
| T5652 | 4341-4342 | , | denotes | , |
| T5651 | 4333-4341 | NN | denotes | addition |
| T5650 | 4330-4332 | IN | denotes | In |
| T5649 | 4328-4329 | . | denotes | . |
| T5648 | 4327-4328 | NNP | denotes | ] |
| T5647 | 4322-4327 | CD | denotes | 21,22 |
| T5646 | 4321-4322 | NNP | denotes | [ |
| T5645 | 4315-4320 | NNP | denotes | IL-17 |
| T5644 | 4311-4314 | CC | denotes | and |
| T5643 | 4309-4310 | NN | denotes | γ |
| T5642 | 4308-4309 | : | denotes | - |
| T5641 | 4307-4308 | -RRB- | denotes | ) |
| T5640 | 4304-4307 | NNP | denotes | IFN |
| T5639 | 4303-4304 | -LRB- | denotes | ( |
| T5638 | 4297-4302 | NN | denotes | gamma |
| T5637 | 4286-4296 | NN | denotes | interferon |
| T5636 | 4283-4285 | IN | denotes | as |
| T5635 | 4278-4282 | JJ | denotes | such |
| T5634 | 4268-4277 | NNS | denotes | cytokines |
| T5633 | 4264-4267 | JJ | denotes | Th1 |
| T5709 | 4705-4710 | VB | denotes | block |
| T5708 | 4701-4704 | MD | denotes | can |
| T5707 | 4695-4700 | WDT | denotes | which |
| T5706 | 4693-4694 | , | denotes | , |
| T5705 | 4690-4693 | NNP | denotes | IgG |
| T5704 | 4689-4690 | : | denotes | - |
| R1976 | T4915 | T4916 | nsubj | IL-10,is |
| R1978 | T4916 | T4916 | ROOT | is,is |
| R1979 | T4917 | T4919 | det | a,cytokine |
| R1982 | T4918 | T4919 | amod | key,cytokine |
| R1983 | T4919 | T4916 | attr | cytokine,is |
| R1984 | T4920 | T4919 | prep | in,cytokine |
| R1985 | T4921 | T4920 | pcomp | regulating,in |
| R1986 | T4922 | T4923 | amod | inflammatory,responses |
| R1987 | T4923 | T4921 | dobj | responses,regulating |
| R1988 | T4924 | T4919 | punct | ",",cytokine |
| R1989 | T4971 | T4972 | nummod | 1,] |
| R1990 | T4972 | T4970 | appos | ],[ |
| R1991 | T4973 | T4937 | punct | .,binds |
| R1992 | T4925 | T4926 | advmod | mainly,by |
| R1993 | T4974 | T4975 | det | The,interaction |
| R1994 | T4975 | T4980 | nsubj | interaction,engages |
| R1995 | T4976 | T4975 | prep | of,interaction |
| R1996 | T4926 | T4916 | prep | by,is |
| R1997 | T4977 | T4976 | pobj | IL-10,of |
| R1998 | T4978 | T4977 | cc | and,IL-10 |
| R1999 | T4927 | T4926 | pcomp | inhibiting,by |
| R2000 | T4979 | T4977 | conj | IL-10R,IL-10 |
| R2001 | T4980 | T4980 | ROOT | engages,engages |
| R2002 | T4981 | T4983 | det | the,kinase |
| R2003 | T4982 | T4983 | compound | Janus,kinase |
| R2004 | T4928 | T4929 | det | the,production |
| R2005 | T4983 | T4980 | dobj | kinase,engages |
| R2006 | T4984 | T4983 | punct | (,kinase |
| R2007 | T4985 | T4983 | appos | JAK,kinase |
| R2008 | T4929 | T4927 | dobj | production,inhibiting |
| R2009 | T4986 | T4985 | punct | ),JAK |
| R2010 | T4987 | T4988 | compound | family,tyrosine |
| R2011 | T4988 | T4989 | nsubj | tyrosine,kinases |
| R2012 | T4930 | T4929 | cc | and,production |
| R2013 | T4989 | T4983 | parataxis | kinases,kinase |
| R2014 | T4990 | T4989 | dobj | Jak1,kinases |
| R2015 | T4991 | T4990 | cc | and,Jak1 |
| R2016 | T4931 | T4929 | conj | function,production |
| R2017 | T4932 | T4929 | prep | of,production |
| R2018 | T4992 | T4990 | conj | Tyk2,Jak1 |
| R2019 | T4993 | T4983 | punct | ",",kinase |
| R2020 | T4933 | T4934 | amod | proinflammatory,cytokines |
| R2021 | T4994 | T4997 | nsubjpass | which,associated |
| R2022 | T4995 | T4997 | auxpass | are,associated |
| R2023 | T4996 | T4997 | advmod | constitutively,associated |
| R2024 | T4934 | T4932 | pobj | cytokines,of |
| R2025 | T4997 | T4983 | relcl | associated,kinase |
| R2026 | T4998 | T4997 | prep | with,associated |
| R2027 | T4999 | T4998 | pobj | IL-10R1,with |
| R2028 | T5000 | T4997 | cc | and,associated |
| R2029 | T5001 | T5003 | nmod | type,IL-10R |
| R2030 | T4935 | T4916 | punct | .,is |
| R2031 | T5002 | T5003 | nummod | 2,IL-10R |
| R2032 | T5003 | T4997 | conj | IL-10R,associated |
| R2033 | T5004 | T5003 | punct | ",",IL-10R |
| R2034 | T4936 | T4937 | amod | IL-10,binds |
| R2035 | T5005 | T5006 | advmod | respectively,[ |
| R2036 | T5006 | T5008 | quantmod | [,] |
| R2037 | T5007 | T5008 | nummod | 2,] |
| R2038 | T5008 | T5003 | appos | ],IL-10R |
| R2039 | T4937 | T4937 | ROOT | binds,binds |
| R2040 | T5009 | T4980 | punct | .,engages |
| R2041 | T5010 | T5011 | nsubj | IL-10,induces |
| R2042 | T5011 | T5011 | ROOT | induces,induces |
| R2043 | T4938 | T4937 | prep | to,binds |
| R2044 | T5012 | T5013 | compound | tyrosine,phosphorylation |
| R2045 | T5013 | T5011 | dobj | phosphorylation,induces |
| R2046 | T4939 | T4941 | det | the,receptor |
| R2047 | T5014 | T5013 | cc | and,phosphorylation |
| R2048 | T5015 | T5013 | conj | activation,phosphorylation |
| R2049 | T5016 | T5013 | prep | of,phosphorylation |
| R2050 | T5017 | T5020 | det | the,factors |
| R2051 | T4940 | T4941 | compound | IL-10,receptor |
| R2052 | T5018 | T5020 | amod | latent,factors |
| R2053 | T5019 | T5020 | amod | transcriptional,factors |
| R2054 | T5020 | T5016 | pobj | factors,of |
| R2055 | T4941 | T4938 | pobj | receptor,to |
| R2056 | T5021 | T5011 | conj | signal,induces |
| R2057 | T5022 | T5021 | dobj | transducer,signal |
| R2058 | T5023 | T5022 | cc | and,transducer |
| R2059 | T4942 | T4941 | punct | (,receptor |
| R2060 | T5024 | T5022 | conj | activator,transducer |
| R2061 | T5025 | T5024 | prep | of,activator |
| R2062 | T5026 | T5025 | pobj | transcription,of |
| R2063 | T4943 | T4941 | appos | IL-10R,receptor |
| R2064 | T5027 | T5026 | punct | (,transcription |
| R2065 | T5028 | T5026 | appos | STAT,transcription |
| R2066 | T5029 | T5026 | punct | ),transcription |
| R2067 | T4944 | T4941 | punct | ),receptor |
| R2068 | T4945 | T4937 | appos | complex,binds |
| R2069 | T5030 | T5026 | nummod | 3,transcription |
| R2070 | T4946 | T4948 | nsubjpass | that,composed |
| R2071 | T5031 | T5024 | cc | and,activator |
| R2072 | T5032 | T5033 | nummod | STAT1,[ |
| R2073 | T5033 | T5024 | conj | [,activator |
| R2074 | T4947 | T4948 | auxpass | is,composed |
| R2075 | T5034 | T5035 | nummod | 3,] |
| R2076 | T5035 | T5033 | appos | ],[ |
| R2077 | T5036 | T5011 | punct | .,induces |
| R2078 | T5037 | T5044 | prep | Upon,form |
| R2079 | T5038 | T5037 | pobj | phosphorylation,Upon |
| R2080 | T5039 | T5044 | punct | ",",form |
| R2081 | T4948 | T4937 | relcl | composed,binds |
| R2082 | T5040 | T5043 | nmod | STAT1,proteins |
| R2083 | T5041 | T5040 | cc | and,STAT1 |
| R2084 | T5042 | T5040 | conj | STAT3,STAT1 |
| R2085 | T4949 | T4948 | prep | of,composed |
| R2086 | T5043 | T5044 | nsubj | proteins,form |
| R2087 | T5044 | T5044 | ROOT | form,form |
| R2088 | T5045 | T5044 | dobj | homodimers,form |
| R2089 | T4950 | T4951 | nummod | two,subunits |
| R2090 | T5046 | T5045 | cc | or,homodimers |
| R2091 | T5047 | T5045 | conj | heterodimers,homodimers |
| R2092 | T5048 | T5044 | punct | ",",form |
| R2093 | T4951 | T4949 | pobj | subunits,of |
| R2094 | T5049 | T5050 | advmod | rapidly,translocate |
| R2095 | T5050 | T5044 | conj | translocate,form |
| R2096 | T5051 | T5050 | prep | into,translocate |
| R2097 | T4952 | T4951 | punct | ",",subunits |
| R2098 | T5052 | T5053 | det | the,nucleus |
| R2099 | T5053 | T5051 | pobj | nucleus,into |
| R2100 | T5054 | T5050 | punct | ",",translocate |
| R2101 | T4953 | T4956 | det | the,component |
| R2102 | T5055 | T5050 | cc | and,translocate |
| R2103 | T5056 | T5050 | conj | modulate,translocate |
| R2104 | T5057 | T5058 | compound | gene,transcription |
| R2105 | T4954 | T4956 | amod | primary,component |
| R2106 | T5058 | T5056 | dobj | transcription,modulate |
| R2107 | T5059 | T5044 | punct | .,form |
| R2108 | T5060 | T5063 | advmod | Intriguingly,is |
| R2109 | T4955 | T4956 | amod | ligand-binding,component |
| R2110 | T5061 | T5063 | punct | ",",is |
| R2111 | T5062 | T5063 | nsubj | STAT3,is |
| R2112 | T5063 | T5063 | ROOT | is,is |
| R2113 | T4956 | T4957 | compound | component,type |
| R2114 | T5064 | T5063 | acomp | indispensable,is |
| R2115 | T5065 | T5063 | prep | for,is |
| R2116 | T5066 | T5072 | det | both,responses |
| R2117 | T4957 | T4951 | appos | type,subunits |
| R2118 | T5067 | T5072 | amod | IL-10-derived,responses |
| R2119 | T4958 | T4959 | nummod | 1,IL-10R |
| R2120 | T4959 | T4957 | appos | IL-10R,type |
| R2121 | T5068 | T5072 | nmod | anti-inflammatory,responses |
| R2122 | T4960 | T4961 | punct | (,IL-10R1 |
| R2123 | T5069 | T5068 | cc | and,anti-inflammatory |
| R2124 | T5070 | T5068 | conj | IL-6-derived,anti-inflammatory |
| R2125 | T4961 | T4959 | appos | IL-10R1,IL-10R |
| R2126 | T5071 | T5072 | amod | proinflammatory,responses |
| R2127 | T5072 | T5065 | pobj | responses,for |
| R2128 | T4962 | T4961 | punct | ),IL-10R1 |
| R2129 | T5073 | T5075 | nmod | [,] |
| R2130 | T5074 | T5075 | nummod | 4,] |
| R2131 | T5075 | T5063 | npadvmod | ],is |
| R2132 | T4963 | T4959 | cc | and,IL-10R |
| R2133 | T5076 | T5063 | punct | .,is |
| R2134 | T5077 | T5083 | nsubj | Studies,shown |
| R2135 | T4964 | T4966 | det | the,component |
| R2136 | T5078 | T5077 | prep | of,Studies |
| R2137 | T5079 | T5081 | amod | cell-type-specific,mice |
| R2138 | T4965 | T4966 | compound | accessory,component |
| R2139 | T5080 | T5081 | amod | STAT3-deficient,mice |
| R2140 | T5081 | T5078 | pobj | mice,of |
| R2141 | T5082 | T5083 | aux | have,shown |
| R2142 | T4966 | T4967 | compound | component,type |
| R2143 | T5083 | T5083 | ROOT | shown,shown |
| R2144 | T5084 | T5087 | mark | that,is |
| R2145 | T4967 | T4959 | conj | type,IL-10R |
| R2146 | T5085 | T5086 | nummod | STAT3,activation |
| R2147 | T5086 | T5087 | nsubj | activation,is |
| R2148 | T5087 | T5083 | ccomp | is,shown |
| R2149 | T4968 | T4967 | nummod | 2,type |
| R2150 | T5088 | T5087 | acomp | essential,is |
| R2151 | T5089 | T5088 | prep | for,essential |
| R2152 | T5090 | T5092 | amod | IL-10-mediated,reactions |
| R2153 | T4969 | T4970 | compound | IL-10R,[ |
| R2154 | T5091 | T5092 | amod | anti-inflammatory,reactions |
| R2155 | T5092 | T5089 | pobj | reactions,for |
| R2156 | T5093 | T5092 | prep | in,reactions |
| R2157 | T4970 | T4967 | appos | [,type |
| R2158 | T5094 | T5093 | pobj | macrophages,in |
| R2159 | T5095 | T5094 | cc | and,macrophages |
| R2160 | T5096 | T5094 | conj | neutrophils,macrophages |
| R2161 | T5165 | T5127 | punct | .,identified |
| R2162 | T5097 | T5099 | nmod | [,] |
| R2163 | T5098 | T5099 | nummod | 5,] |
| R2164 | T5099 | T5083 | dobj | ],shown |
| R2165 | T5100 | T5083 | punct | ",",shown |
| R2166 | T5166 | T5167 | amod | Recent,studies |
| R2167 | T5101 | T5083 | cc | but,shown |
| R2168 | T5102 | T5083 | conj | is,shown |
| R2169 | T5103 | T5102 | acomp | responsible,is |
| R2170 | T5104 | T5103 | prep | for,responsible |
| R2171 | T5167 | T5168 | nsubj | studies,indicate |
| R2172 | T5105 | T5106 | amod | IL-6-mediated,prevention |
| R2173 | T5106 | T5104 | pobj | prevention,for |
| R2174 | T5107 | T5106 | prep | of,prevention |
| R2175 | T5168 | T5168 | ROOT | indicate,indicate |
| R2176 | T5108 | T5107 | pobj | apoptosis,of |
| R2177 | T5109 | T5106 | prep | in,prevention |
| R2178 | T5110 | T5111 | compound | T,cells |
| R2179 | T5111 | T5109 | pobj | cells,in |
| R2180 | T5112 | T5114 | nmod | [,] |
| R2181 | T5113 | T5114 | nummod | 6,] |
| R2182 | T5169 | T5171 | mark | that,plays |
| R2183 | T5114 | T5114 | ROOT | ],] |
| R2184 | T5115 | T5083 | punct | .,shown |
| R2185 | T5116 | T5117 | det | The,suppressor |
| R2186 | T5170 | T5171 | nsubj | SOCS3,plays |
| R2187 | T5117 | T5117 | ROOT | suppressor,suppressor |
| R2188 | T5118 | T5117 | prep | of,suppressor |
| R2189 | T5119 | T5118 | pobj | cytokine,of |
| R2190 | T5171 | T5168 | ccomp | plays,indicate |
| R2191 | T5120 | T5117 | acl | signaling,suppressor |
| R2192 | T5121 | T5120 | punct | (,signaling |
| R2193 | T5122 | T5120 | appos | SOCS,signaling |
| R2194 | T5172 | T5174 | det | a,role |
| R2195 | T5123 | T5120 | punct | ),signaling |
| R2196 | T5124 | T5127 | nsubjpass | proteins,identified |
| R2197 | T5125 | T5127 | aux | have,identified |
| R2198 | T5173 | T5174 | amod | key,role |
| R2199 | T5126 | T5127 | auxpass | been,identified |
| R2200 | T5127 | T5127 | ROOT | identified,identified |
| R2201 | T5128 | T5127 | prep | as,identified |
| R2202 | T5174 | T5171 | dobj | role,plays |
| R2203 | T5129 | T5130 | det | a,family |
| R2204 | T5130 | T5128 | pobj | family,as |
| R2205 | T5175 | T5174 | prep | in,role |
| R2206 | T5131 | T5130 | prep | of,family |
| R2207 | T5132 | T5135 | amod | endogenous,inhibitors |
| R2208 | T5133 | T5135 | nmod | JAK,inhibitors |
| R2209 | T5134 | T5135 | compound | kinase,inhibitors |
| R2210 | T5176 | T5175 | pcomp | regulating,in |
| R2211 | T5135 | T5131 | pobj | inhibitors,of |
| R2212 | T5136 | T5138 | nsubj | that,act |
| R2213 | T5137 | T5138 | aux | can,act |
| R2214 | T5177 | T5179 | det | the,action |
| R2215 | T5138 | T5135 | relcl | act,inhibitors |
| R2216 | T5139 | T5138 | prep | in,act |
| R2217 | T5140 | T5143 | amod | classic,loops |
| R2218 | T5178 | T5179 | amod | divergent,action |
| R2219 | T5141 | T5142 | compound | feedback,inhibition |
| R2220 | T5142 | T5143 | compound | inhibition,loops |
| R2221 | T5143 | T5139 | pobj | loops,in |
| R2222 | T5179 | T5176 | dobj | action,regulating |
| R2223 | T5144 | T5127 | punct | ",",identified |
| R2224 | T5145 | T5127 | cc | but,identified |
| R2225 | T5146 | T5147 | poss | their,roles |
| R2226 | T5180 | T5179 | prep | of,action |
| R2227 | T5147 | T5127 | conj | roles,identified |
| R2228 | T5148 | T5147 | prep | as,roles |
| R2229 | T5149 | T5150 | det | the,mediators |
| R2230 | T5150 | T5148 | pobj | mediators,as |
| R2231 | T5181 | T5180 | pobj | IL-10,of |
| R2232 | T5151 | T5150 | prep | of,mediators |
| R2233 | T5152 | T5153 | compound | crosstalk,inhibition |
| R2234 | T5153 | T5151 | pobj | inhibition,of |
| R2235 | T5182 | T5181 | cc | and,IL-10 |
| R2236 | T5154 | T5127 | agent | by,identified |
| R2237 | T5155 | T5154 | pcomp | opposing,by |
| R2238 | T5156 | T5155 | dobj | cytokine,opposing |
| R2239 | T5183 | T5181 | conj | IL-6,IL-10 |
| R2240 | T5157 | T5155 | conj | signaling,opposing |
| R2241 | T5158 | T5161 | nsubjpass | pathways,clarified |
| R2242 | T5184 | T5171 | punct | ",",plays |
| R2243 | T5159 | T5161 | aux | have,clarified |
| R2244 | T5160 | T5161 | auxpass | been,clarified |
| R2245 | T5161 | T5157 | ccomp | clarified,signaling |
| R2246 | T5185 | T5171 | prep | by,plays |
| R2247 | T5162 | T5164 | nmod | [,] |
| R2248 | T5163 | T5164 | nummod | 7,] |
| R2249 | T5164 | T5161 | dobj | ],clarified |
| R2250 | T5186 | T5187 | advmod | specifically,blocking |
| R2251 | T5187 | T5185 | pcomp | blocking,by |
| R2252 | T5188 | T5189 | nummod | STAT3,activation |
| R2253 | T5189 | T5187 | dobj | activation,blocking |
| R2254 | T5262 | T5260 | pobj | cytokines,of |
| R2255 | T5263 | T5256 | punct | .,are |
| R2256 | T5190 | T5189 | acl | induced,activation |
| R2257 | T5264 | T5267 | compound | Tumor,alpha |
| R2258 | T5265 | T5266 | compound | necrosis,factor |
| R2259 | T5266 | T5267 | compound | factor,alpha |
| R2260 | T5191 | T5190 | agent | by,induced |
| R2261 | T5267 | T5279 | nsubj | alpha,are |
| R2262 | T5268 | T5269 | punct | (,TNF-α |
| R2263 | T5269 | T5267 | appos | TNF-α,alpha |
| R2264 | T5192 | T5191 | pobj | IL-6,by |
| R2265 | T5270 | T5269 | punct | ),TNF-α |
| R2266 | T5271 | T5267 | cc | and,alpha |
| R2267 | T5272 | T5267 | conj | IL-1,alpha |
| R2268 | T5193 | T5190 | cc | but,induced |
| R2269 | T5273 | T5272 | punct | ",",IL-1 |
| R2270 | T5274 | T5277 | nummod | two,products |
| R2271 | T5275 | T5277 | amod | major,products |
| R2272 | T5194 | T5196 | neg | not,induced |
| R2273 | T5276 | T5277 | compound | macrophage,products |
| R2274 | T5277 | T5267 | appos | products,alpha |
| R2275 | T5195 | T5196 | nsubj | that,induced |
| R2276 | T5278 | T5279 | punct | ",",are |
| R2277 | T5279 | T5279 | ROOT | are,are |
| R2278 | T5280 | T5279 | acomp | crucial,are |
| R2279 | T5281 | T5279 | prep | in,are |
| R2280 | T5282 | T5283 | det | the,process |
| R2281 | T5283 | T5281 | pobj | process,in |
| R2282 | T5284 | T5283 | prep | of,process |
| R2283 | T5196 | T5190 | conj | induced,induced |
| R2284 | T5285 | T5286 | amod | chronic,inflammation |
| R2285 | T5286 | T5284 | pobj | inflammation,of |
| R2286 | T5287 | T5286 | cc | and,inflammation |
| R2287 | T5197 | T5196 | agent | by,induced |
| R2288 | T5288 | T5289 | amod | joint,destruction |
| R2289 | T5289 | T5286 | conj | destruction,inflammation |
| R2290 | T5290 | T5279 | punct | ",",are |
| R2291 | T5198 | T5199 | compound | IL-10,[ |
| R2292 | T5291 | T5279 | cc | and,are |
| R2293 | T5292 | T5293 | nsubj | they,give |
| R2294 | T5293 | T5279 | conj | give,are |
| R2295 | T5199 | T5197 | pobj | [,by |
| R2296 | T5294 | T5293 | dobj | rise,give |
| R2297 | T5295 | T5296 | aux | to,effector |
| R2298 | T5200 | T5201 | nummod | "8,9",] |
| R2299 | T5296 | T5294 | advcl | effector,rise |
| R2300 | T5297 | T5296 | dobj | components,effector |
| R2301 | T5298 | T5297 | punct | ",",components |
| R2302 | T5299 | T5297 | prep | including,components |
| R2303 | T5201 | T5199 | appos | ],[ |
| R2304 | T5300 | T5302 | amod | other,cytokines |
| R2305 | T5301 | T5302 | amod | inflammatory,cytokines |
| R2306 | T5302 | T5299 | pobj | cytokines,including |
| R2307 | T5202 | T5168 | punct | .,indicate |
| R2308 | T5303 | T5302 | punct | ",",cytokines |
| R2309 | T5304 | T5302 | conj | chemokines,cytokines |
| R2310 | T5305 | T5304 | punct | ",",chemokines |
| R2311 | T5203 | T5205 | det | The,membrane |
| R2312 | T5306 | T5307 | compound | growth,factors |
| R2313 | T5307 | T5304 | conj | factors,chemokines |
| R2314 | T5204 | T5205 | amod | synovial,membrane |
| R2315 | T5205 | T5213 | nsubjpass | membrane,characterized |
| R2318 | T5206 | T5205 | prep | of,membrane |
| R2320 | T5207 | T5208 | amod | rheumatoid,arthritis |
| R2321 | T5208 | T5206 | pobj | arthritis,of |
| R2325 | T5209 | T5210 | punct | (,RA |
| R2330 | T5210 | T5208 | appos | RA,arthritis |
| R2335 | T5211 | T5205 | punct | ),membrane |
| R2338 | T5212 | T5213 | auxpass | is,characterized |
| R2342 | T5213 | T5213 | ROOT | characterized,characterized |
| R2345 | T5214 | T5213 | agent | by,characterized |
| R2349 | T5215 | T5216 | det | an,infiltrate |
| R2354 | T5216 | T5214 | pobj | infiltrate,by |
| R2357 | T5217 | T5216 | prep | of,infiltrate |
| R2361 | T5218 | T5219 | det | a,variety |
| R2363 | T5342 | T5339 | dobj | response,simulating |
| R2364 | T5343 | T5339 | punct | ",",simulating |
| R2365 | T5219 | T5217 | pobj | variety,of |
| R2366 | T5344 | T5345 | compound | B-cell,maturation |
| R2367 | T5345 | T5339 | conj | maturation,simulating |
| R2368 | T5220 | T5219 | prep | of,variety |
| R2369 | T5221 | T5222 | amod | inflammatory,cells |
| R2370 | T5346 | T5345 | prep | into,maturation |
| R2371 | T5347 | T5348 | compound | plasma,cells |
| R2372 | T5222 | T5220 | pobj | cells,of |
| R2373 | T5348 | T5346 | pobj | cells,into |
| R2374 | T5349 | T5345 | punct | ",",maturation |
| R2375 | T5350 | T5351 | compound | T-cell,functions |
| R2376 | T5223 | T5222 | punct | ",",cells |
| R2377 | T5351 | T5345 | conj | functions,maturation |
| R2378 | T5352 | T5351 | punct | ",",functions |
| R2379 | T5353 | T5351 | cc | and,functions |
| R2380 | T5224 | T5225 | amod | such,as |
| R2383 | T5225 | T5222 | prep | as,cells |
| R2387 | T5226 | T5225 | pobj | lymphocytes,as |
| R2391 | T5227 | T5226 | punct | ",",lymphocytes |
| R2393 | T5228 | T5226 | conj | macrophages,lymphocytes |
| R2397 | T5229 | T5228 | punct | ",",macrophages |
| R2401 | T5230 | T5228 | cc | and,macrophages |
| R2405 | T5231 | T5232 | amod | dendritic,cells |
| R2407 | T5373 | T5374 | amod | large,quantities |
| R2408 | T5374 | T5372 | pobj | quantities,in |
| R2409 | T5232 | T5228 | conj | cells,macrophages |
| R2410 | T5375 | T5369 | prep | in,are |
| R2411 | T5376 | T5377 | compound | RA,joints |
| R2412 | T5377 | T5375 | pobj | joints,in |
| R2413 | T5233 | T5216 | punct | ",",infiltrate |
| R2414 | T5378 | T5369 | punct | .,are |
| R2415 | T5379 | T5399 | nsubjpass | IL-10,known |
| R2416 | T5380 | T5379 | punct | ",",IL-10 |
| R2417 | T5234 | T5235 | advmod | together,with |
| R2418 | T5381 | T5379 | acl | produced,IL-10 |
| R2419 | T5382 | T5381 | agent | by,produced |
| R2420 | T5235 | T5216 | prep | with,infiltrate |
| R2421 | T5383 | T5382 | pobj | macrophages,by |
| R2422 | T5384 | T5381 | cc | and,produced |
| R2423 | T5385 | T5386 | advmod | partly,by |
| R2424 | T5386 | T5399 | prep | by,known |
| R2425 | T5236 | T5235 | pobj | proliferation,with |
| R2426 | T5387 | T5388 | compound | T,cells |
| R2427 | T5388 | T5386 | pobj | cells,by |
| R2428 | T5237 | T5236 | prep | of,proliferation |
| R2429 | T5389 | T5388 | prep | in,cells |
| R2430 | T5390 | T5392 | det | the,tissue |
| R2431 | T5391 | T5392 | amod | synovial,tissue |
| R2432 | T5392 | T5389 | pobj | tissue,in |
| R2433 | T5393 | T5394 | punct | (,ST |
| R2434 | T5394 | T5392 | appos | ST,tissue |
| R2435 | T5395 | T5392 | punct | ),tissue |
| R2436 | T5238 | T5240 | amod | synovial,cells |
| R2437 | T5239 | T5240 | amod | fibroblast-like,cells |
| R2438 | T5396 | T5397 | punct | ",",is |
| R2439 | T5397 | T5399 | auxpass | is,known |
| R2440 | T5398 | T5399 | advmod | best,known |
| R2441 | T5240 | T5237 | pobj | cells,of |
| R2442 | T5399 | T5399 | ROOT | known,known |
| R2443 | T5400 | T5399 | prep | as,known |
| R2444 | T5241 | T5213 | punct | .,characterized |
| R2445 | T5401 | T5403 | det | a,regulator |
| R2446 | T5402 | T5403 | amod | negative,regulator |
| R2447 | T5403 | T5400 | pobj | regulator,as |
| R2448 | T5242 | T5243 | amod | Numerous,cytokines |
| R2449 | T5404 | T5403 | prep | for,regulator |
| R2450 | T5243 | T5245 | nsubjpass | cytokines,overproduced |
| R2451 | T5244 | T5245 | auxpass | are,overproduced |
| R2452 | T5405 | T5404 | pobj | macrophage,for |
| R2453 | T5406 | T5405 | cc | and,macrophage |
| R2454 | T5245 | T5245 | ROOT | overproduced,overproduced |
| R2455 | T5407 | T5408 | amod | Th1,cells |
| R2456 | T5408 | T5405 | conj | cells,macrophage |
| R2457 | T5409 | T5399 | punct | ",",known |
| R2458 | T5246 | T5245 | prep | in,overproduced |
| R2459 | T5410 | T5399 | cc | but,known |
| R2460 | T5411 | T5413 | det | the,level |
| R2461 | T5247 | T5249 | det | the,joint |
| R2462 | T5412 | T5413 | compound | expression,level |
| R2463 | T5413 | T5414 | nsubj | level,is |
| R2464 | T5248 | T5249 | amod | inflamed,joint |
| R2465 | T5414 | T5399 | conj | is,known |
| R2466 | T5249 | T5246 | pobj | joint,in |
| R2467 | T5415 | T5414 | acomp | insufficient,is |
| R2468 | T5416 | T5417 | aux | to,counterbalance |
| R2469 | T5417 | T5415 | xcomp | counterbalance,insufficient |
| R2470 | T5250 | T5245 | punct | ",",overproduced |
| R2471 | T5418 | T5419 | det | the,cascade |
| R2472 | T5419 | T5417 | dobj | cascade,counterbalance |
| R2473 | T5420 | T5419 | prep | of,cascade |
| R2474 | T5421 | T5422 | amod | proinflammatory,events |
| R2475 | T5251 | T5245 | cc | and,overproduced |
| R2476 | T5422 | T5420 | pobj | events,of |
| R2477 | T5423 | T5425 | nmod | [,] |
| R2478 | T5252 | T5256 | nsubj | macrophages,are |
| R2479 | T5424 | T5425 | nummod | 12,] |
| R2480 | T5425 | T5419 | appos | ],cascade |
| R2481 | T5426 | T5414 | punct | .,is |
| R2482 | T5427 | T5435 | prep | In,appears |
| R2483 | T5428 | T5427 | pobj | addition,In |
| R2484 | T5429 | T5435 | punct | ",",appears |
| R2485 | T5430 | T5432 | det | the,action |
| R2486 | T5253 | T5252 | cc | and,macrophages |
| R2487 | T5431 | T5432 | amod | anti-inflammatory,action |
| R2488 | T5432 | T5435 | nsubj | action,appears |
| R2489 | T5433 | T5432 | prep | of,action |
| R2490 | T5254 | T5255 | amod | synovial,fibroblasts |
| R2491 | T5434 | T5433 | pobj | IL-10,of |
| R2492 | T5435 | T5435 | ROOT | appears,appears |
| R2493 | T5255 | T5252 | conj | fibroblasts,macrophages |
| R2494 | T5436 | T5438 | aux | to,modulated |
| R2495 | T5437 | T5438 | auxpass | be,modulated |
| R2496 | T5438 | T5435 | xcomp | modulated,appears |
| R2497 | T5256 | T5245 | conj | are,overproduced |
| R2498 | T5439 | T5438 | prep | at,modulated |
| R2499 | T5440 | T5441 | det | the,level |
| R2500 | T5441 | T5439 | pobj | level,at |
| R2501 | T5257 | T5259 | det | an,source |
| R2502 | T5258 | T5259 | amod | important,source |
| R2503 | T5442 | T5441 | prep | of,level |
| R2504 | T5259 | T5256 | attr | source,are |
| R2505 | T5443 | T5444 | compound | signal,transduction |
| R2506 | T5444 | T5442 | pobj | transduction,of |
| R2507 | T5445 | T5438 | prep | during,modulated |
| R2508 | T5260 | T5259 | prep | of,source |
| R2509 | T5446 | T5447 | amod | chronic,inflammation |
| R2510 | T5447 | T5445 | pobj | inflammation,during |
| R2511 | T5448 | T5435 | punct | .,appears |
| R2512 | T5261 | T5262 | amod | proinflammatory,cytokines |
| R2513 | T5449 | T5452 | nsubjpass | IL-10,impaired |
| R2514 | T5450 | T5452 | nsubjpass | signaling,impaired |
| R2515 | T5451 | T5452 | auxpass | is,impaired |
| R2516 | T5506 | T5509 | nsubjpass | cells,activated |
| R2517 | T5452 | T5452 | ROOT | impaired,impaired |
| R2518 | T5453 | T5452 | prep | in,impaired |
| R2519 | T5454 | T5453 | pobj | macrophages,in |
| R2520 | T5507 | T5509 | aux | may,activated |
| R2521 | T5455 | T5452 | prep | upon,impaired |
| R2522 | T5456 | T5457 | amod | chronic,exposure |
| R2523 | T5457 | T5455 | pobj | exposure,upon |
| R2524 | T5508 | T5509 | auxpass | be,activated |
| R2525 | T5458 | T5457 | prep | to,exposure |
| R2526 | T5459 | T5460 | amod | proinflammatory,cytokines |
| R2527 | T5460 | T5458 | pobj | cytokines,to |
| R2528 | T5509 | T5509 | ROOT | activated,activated |
| R2529 | T5461 | T5462 | amod | such,as |
| R2530 | T5462 | T5460 | prep | as,cytokines |
| R2531 | T5463 | T5468 | nmod | TNF-α,complexes |
| R2532 | T5464 | T5463 | cc | and,TNF-α |
| R2533 | T5465 | T5463 | conj | IL-1,TNF-α |
| R2534 | T5466 | T5465 | cc | and,IL-1 |
| R2535 | T5510 | T5509 | agent | by,activated |
| R2536 | T5467 | T5465 | conj | immune,IL-1 |
| R2537 | T5468 | T5462 | pobj | complexes,as |
| R2538 | T5469 | T5471 | compound | [,] |
| R2539 | T5511 | T5512 | amod | arthritogenic,antigens |
| R2540 | T5470 | T5471 | compound | "13,14",] |
| R2541 | T5471 | T5468 | appos | ],complexes |
| R2542 | T5472 | T5452 | punct | .,impaired |
| R2543 | T5512 | T5510 | pobj | antigens,by |
| R2544 | T5473 | T5474 | compound | Cell,surface |
| R2545 | T5474 | T5475 | compound | surface,expression |
| R2546 | T5513 | T5509 | punct | ",",activated |
| R2547 | T5475 | T5479 | nsubjpass | expression,decreased |
| R2548 | T5476 | T5475 | prep | of,expression |
| R2549 | T5477 | T5476 | pobj | IL-10R1,of |
| R2550 | T5478 | T5479 | auxpass | is,decreased |
| R2551 | T5514 | T5509 | prep | in,activated |
| R2552 | T5479 | T5479 | ROOT | decreased,decreased |
| R2553 | T5480 | T5479 | prep | in,decreased |
| R2554 | T5515 | T5514 | pobj | conjunction,in |
| R2555 | T5481 | T5484 | amod | synovial,cells |
| R2556 | T5482 | T5484 | amod | fluid,cells |
| R2557 | T5483 | T5484 | amod | dendritic,cells |
| R2558 | T5516 | T5515 | prep | with,conjunction |
| R2559 | T5484 | T5480 | pobj | cells,in |
| R2560 | T5485 | T5479 | conj | due,decreased |
| R2561 | T5517 | T5519 | nsubj | CD28-mediated,signaling |
| R2562 | T5486 | T5485 | pcomp | to,due |
| R2563 | T5487 | T5488 | det | the,presence |
| R2564 | T5488 | T5485 | pobj | presence,due |
| R2565 | T5518 | T5519 | amod | costimulatory,signaling |
| R2566 | T5489 | T5488 | prep | of,presence |
| R2567 | T5490 | T5489 | pobj | TNF-α,of |
| R2568 | T5519 | T5516 | pcomp | signaling,with |
| R2569 | T5491 | T5490 | punct | ",",TNF-α |
| R2570 | T5492 | T5490 | conj | IL-1,TNF-α |
| R2571 | T5520 | T5519 | punct | ",",signaling |
| R2572 | T5493 | T5492 | punct | ",",IL-1 |
| R2573 | T5521 | T5519 | prep | in,signaling |
| R2574 | T5494 | T5492 | cc | and,IL-1 |
| R2575 | T5495 | T5492 | conj | granulocyte,IL-1 |
| R2576 | T5496 | T5498 | nmod | macrophage,factor |
| R2577 | T5522 | T5521 | pobj | RA,in |
| R2578 | T5497 | T5498 | compound | colony-stimulating,factor |
| R2579 | T5498 | T5488 | appos | factor,presence |
| R2580 | T5499 | T5501 | nmod | [,] |
| R2581 | T5500 | T5501 | nummod | 15,] |
| R2582 | T5501 | T5498 | appos | ],factor |
| R2583 | T5523 | T5509 | punct | .,activated |
| R2584 | T5502 | T5479 | punct | .,decreased |
| R2585 | T5503 | T5509 | nsubjpass | CD4,activated |
| R2586 | T5504 | T5506 | nummod | +,cells |
| R2587 | T5524 | T5525 | det | The,significance |
| R2588 | T5505 | T5506 | compound | T,cells |
| R2589 | T5525 | T5532 | nsubjpass | significance,supported |
| R2590 | T5526 | T5525 | prep | of,significance |
| R2591 | T5537 | T5541 | det | the,antigens |
| R2592 | T5538 | T5540 | compound | MHC,II |
| R2593 | T5527 | T5529 | det | this,process |
| R2594 | T5539 | T5540 | compound | class,II |
| R2595 | T5540 | T5541 | compound | II,antigens |
| R2596 | T5528 | T5529 | amod | autoimmune,process |
| R2597 | T5541 | T5536 | pobj | antigens,of |
| R2598 | T5542 | T5541 | appos | HLA-DRB1,antigens |
| R2599 | T5529 | T5526 | pobj | process,of |
| R2600 | T5543 | T5532 | punct | *,supported |
| R2601 | T5544 | T5544 | ROOT | 0404,0404 |
| R2602 | T5545 | T5544 | cc | and,0404 |
| R2603 | T5530 | T5532 | aux | has,supported |
| R2604 | T5546 | T5544 | conj | HLA-DRB1,0404 |
| R2605 | T5547 | T5546 | punct | *,HLA-DRB1 |
| R2606 | T5548 | T5546 | amod | 0401,HLA-DRB1 |
| R2607 | T5531 | T5532 | auxpass | been,supported |
| R2608 | T5549 | T5546 | prep | with,HLA-DRB1 |
| R2609 | T5550 | T5551 | compound | disease,susceptibility |
| R2610 | T5551 | T5549 | pobj | susceptibility,with |
| R2611 | T5532 | T5532 | ROOT | supported,supported |
| R2612 | T5552 | T5551 | cc | and,susceptibility |
| R2613 | T5553 | T5551 | conj | severity,susceptibility |
| R2614 | T5554 | T5556 | compound | [,] |
| R2615 | T5555 | T5556 | compound | "16,17",] |
| R2616 | T5533 | T5532 | agent | by,supported |
| R2617 | T5556 | T5546 | conj | ],HLA-DRB1 |
| R2618 | T5557 | T5556 | punct | ",",] |
| R2619 | T5558 | T5544 | cc | and,0404 |
| R2620 | T5534 | T5535 | det | the,linkage |
| R2621 | T5559 | T5544 | conj | by,0404 |
| R2622 | T5560 | T5562 | det | the,expression |
| R2623 | T5561 | T5562 | amod | high-level,expression |
| R2624 | T5535 | T5533 | pobj | linkage,by |
| R2625 | T5562 | T5559 | pobj | expression,by |
| R2626 | T5563 | T5562 | prep | of,expression |
| R2627 | T5564 | T5567 | compound | MHC,molecules |
| R2628 | T5536 | T5535 | prep | of,linkage |
| R2629 | T5565 | T5567 | compound | class,molecules |
| R2630 | T5566 | T5567 | compound | II,molecules |
| R2631 | T5567 | T5563 | pobj | molecules,of |
| R2632 | T5568 | T5544 | cc | and,0404 |
| R2633 | T5569 | T5571 | det | both,ligands |
| R2634 | T5604 | T5602 | prep | in,be |
| R2635 | T5570 | T5571 | nummod | CD28,ligands |
| R2636 | T5605 | T5604 | pcomp | sustaining,in |
| R2637 | T5571 | T5544 | conj | ligands,0404 |
| R2638 | T5572 | T5571 | punct | ",",ligands |
| R2639 | T5573 | T5571 | conj | CD80,ligands |
| R2640 | T5574 | T5573 | cc | and,CD80 |
| R2641 | T5606 | T5607 | det | the,activation |
| R2642 | T5575 | T5573 | conj | CD86,CD80 |
| R2643 | T5576 | T5571 | punct | ",",ligands |
| R2644 | T5577 | T5544 | prep | in,0404 |
| R2645 | T5607 | T5605 | dobj | activation,sustaining |
| R2646 | T5578 | T5583 | det | the,] |
| R2647 | T5579 | T5583 | amod | inflamed,] |
| R2648 | T5608 | T5607 | prep | of,activation |
| R2649 | T5580 | T5581 | compound | ST,[ |
| R2650 | T5581 | T5583 | nmod | [,] |
| R2651 | T5609 | T5608 | pobj | macrophages,of |
| R2652 | T5582 | T5583 | nummod | 18-20,] |
| R2653 | T5583 | T5577 | pobj | ],in |
| R2654 | T5584 | T5544 | punct | .,0404 |
| R2655 | T5610 | T5609 | cc | and,macrophages |
| R2656 | T5585 | T5587 | det | The,emergence |
| R2657 | T5586 | T5587 | amod | continuing,emergence |
| R2658 | T5587 | T5602 | nsubj | emergence,be |
| R2659 | T5611 | T5612 | amod | synovial,fibroblasts |
| R2660 | T5588 | T5587 | prep | of,emergence |
| R2661 | T5589 | T5593 | amod | activated,cells |
| R2662 | T5612 | T5609 | conj | fibroblasts,macrophages |
| R2663 | T5590 | T5593 | compound | CD4,cells |
| R2664 | T5591 | T5593 | nummod | +,cells |
| R2665 | T5613 | T5605 | prep | through,sustaining |
| R2666 | T5592 | T5593 | compound | T,cells |
| R2667 | T5593 | T5588 | pobj | cells,of |
| R2668 | T5594 | T5587 | punct | ",",emergence |
| R2669 | T5614 | T5615 | compound | cell,surface |
| R2670 | T5595 | T5597 | advmod | even,few |
| R2671 | T5596 | T5597 | advmod | though,few |
| R2672 | T5597 | T5602 | advcl | few,be |
| R2673 | T5615 | T5613 | pobj | surface,through |
| R2674 | T5598 | T5597 | prep | in,few |
| R2675 | T5599 | T5598 | pobj | number,in |
| R2676 | T5600 | T5602 | punct | ",",be |
| R2677 | T5616 | T5605 | conj | signaling,sustaining |
| R2678 | T5601 | T5602 | aux | may,be |
| R2679 | T5602 | T5602 | ROOT | be,be |
| R2680 | T5603 | T5602 | acomp | crucial,be |
| R2681 | T5617 | T5616 | prep | by,signaling |
| R2682 | T5633 | T5634 | amod | Th1,cytokines |
| R2683 | T5618 | T5617 | pobj | means,by |
| R2684 | T5634 | T5631 | pobj | cytokines,of |
| R2685 | T5635 | T5636 | amod | such,as |
| R2686 | T5636 | T5634 | prep | as,cytokines |
| R2687 | T5619 | T5618 | prep | of,means |
| R2688 | T5637 | T5638 | compound | interferon,gamma |
| R2689 | T5638 | T5636 | pobj | gamma,as |
| R2690 | T5639 | T5640 | punct | (,IFN |
| R2691 | T5620 | T5621 | compound | cell,surface |
| R2692 | T5640 | T5638 | appos | IFN,gamma |
| R2693 | T5641 | T5640 | punct | ),IFN |
| R2694 | T5642 | T5638 | punct | -,gamma |
| R2695 | T5621 | T5622 | compound | surface,CD69 |
| R2696 | T5643 | T5638 | conj | γ,gamma |
| R2697 | T5644 | T5643 | cc | and,γ |
| R2698 | T5645 | T5646 | compound | IL-17,[ |
| R2699 | T5622 | T5619 | pobj | CD69,of |
| R2700 | T5646 | T5630 | appos | [,release |
| R2701 | T5647 | T5648 | compound | "21,22",] |
| R2702 | T5648 | T5646 | appos | ],[ |
| R2703 | T5623 | T5622 | cc | and,CD69 |
| R2704 | T5649 | T5602 | punct | .,be |
| R2705 | T5624 | T5622 | conj | CD11,CD69 |
| R2706 | T5650 | T5658 | prep | In,stimulate |
| R2707 | T5625 | T5616 | punct | ",",signaling |
| R2708 | T5651 | T5650 | pobj | addition,In |
| R2709 | T5652 | T5658 | punct | ",",stimulate |
| R2710 | T5653 | T5655 | compound | CD4,T |
| R2711 | T5626 | T5628 | advmod | as,as |
| R2712 | T5654 | T5655 | compound | +,T |
| R2713 | T5655 | T5656 | compound | T,cells |
| R2714 | T5656 | T5658 | nsubj | cells,stimulate |
| R2715 | T5627 | T5628 | advmod | well,as |
| R2716 | T5657 | T5658 | aux | could,stimulate |
| R2717 | T5658 | T5658 | ROOT | stimulate,stimulate |
| R2718 | T5628 | T5630 | cc | as,release |
| R2719 | T5659 | T5660 | amod | B-cell,production |
| R2720 | T5660 | T5658 | dobj | production,stimulate |
| R2721 | T5629 | T5630 | det | the,release |
| R2722 | T5661 | T5660 | prep | of,production |
| R2723 | T5662 | T5661 | pobj | autoantibodies,of |
| R2724 | T5663 | T5664 | amod | such,as |
| R2725 | T5630 | T5602 | advcl | release,be |
| R2726 | T5664 | T5662 | prep | as,autoantibodies |
| R2727 | T5665 | T5666 | amod | rheumatoid,factor |
| R2728 | T5666 | T5664 | pobj | factor,as |
| R2729 | T5631 | T5630 | prep | of,release |
| R2730 | T5667 | T5666 | cc | and,factor |
| R2731 | T5668 | T5670 | amod | osteoclast-mediated,destruction |
| R2732 | T5669 | T5670 | compound | bone,destruction |
| R2733 | T5670 | T5666 | conj | destruction,factor |
| R2734 | T5671 | T5658 | punct | .,stimulate |
| R2735 | T5632 | T5634 | amod | proinflammatory,cytokines |
| R2736 | T5672 | T5674 | poss | Their,role |
| R2737 | T5673 | T5674 | amod | obligatory,role |
| R2738 | T5674 | T5680 | nsubjpass | role,proved |
| R2739 | T5704 | T5705 | punct | -,IgG |
| R2740 | T5675 | T5674 | prep | in,role |
| R2741 | T5676 | T5677 | compound | RA,synovitis |
| R2742 | T5677 | T5675 | pobj | synovitis,in |
| R2743 | T5678 | T5680 | auxpass | was,proved |
| R2744 | T5679 | T5680 | advmod | recently,proved |
| R2745 | T5680 | T5680 | ROOT | proved,proved |
| R2746 | T5705 | T5695 | appos | IgG,protein |
| R2747 | T5681 | T5680 | agent | by,proved |
| R2748 | T5682 | T5683 | amod | successful,treatment |
| R2749 | T5683 | T5681 | pobj | treatment,by |
| R2750 | T5706 | T5695 | punct | ",",protein |
| R2751 | T5684 | T5683 | prep | of,treatment |
| R2752 | T5685 | T5686 | amod | active,disease |
| R2753 | T5686 | T5684 | pobj | disease,of |
| R2754 | T5687 | T5680 | agent | by,proved |
| R2755 | T5707 | T5709 | nsubj | which,block |
| R2756 | T5688 | T5689 | amod | selective,inhibition |
| R2757 | T5689 | T5687 | pobj | inhibition,by |
| R2758 | T5690 | T5689 | prep | of,inhibition |
| R2759 | T5708 | T5709 | aux | can,block |
| R2760 | T5691 | T5692 | compound | T-cell,activation |
| R2761 | T5692 | T5690 | pobj | activation,of |
| R2762 | T5693 | T5680 | prep | with,proved |
| R2763 | T5709 | T5695 | relcl | block,protein |
| R2764 | T5694 | T5695 | compound | fusion,protein |
| R2765 | T5695 | T5693 | pobj | protein,with |
| R2766 | T5710 | T5711 | det | the,engagement |
| R2767 | T5696 | T5695 | prep | of,protein |
| R2768 | T5697 | T5699 | amod | cytotoxic,antigen |
| R2769 | T5698 | T5699 | amod | T-cell-associated,antigen |
| R2770 | T5699 | T5696 | pobj | antigen,of |
| R2771 | T5711 | T5709 | dobj | engagement,block |
| R2772 | T5700 | T5699 | nummod | 4,antigen |
| R2773 | T5701 | T5699 | punct | (,antigen |
| R2774 | T5702 | T5699 | appos | CD152,antigen |
| R2775 | T5712 | T5711 | prep | of,engagement |
| R2776 | T5703 | T5699 | punct | ),antigen |
| R2777 | T5713 | T5712 | pobj | CD28,of |
| R2778 | T5714 | T5709 | prep | on,block |
| R2779 | T5715 | T5716 | compound | T,cells |
| R2780 | T5729 | T5680 | punct | .,proved |
| R2781 | T5730 | T5732 | nsubj | IL-10,blocks |
| R2782 | T5731 | T5732 | advmod | efficiently,blocks |
| R2783 | T5732 | T5732 | ROOT | blocks,blocks |
| R2784 | T5716 | T5714 | pobj | cells,on |
| R2785 | T5733 | T5737 | det | the,response |
| R2786 | T5734 | T5737 | amod | antigen-specific,response |
| R2787 | T5735 | T5737 | compound | T-cell,response |
| R2788 | T5717 | T5709 | prep | by,block |
| R2789 | T5736 | T5737 | compound | cytokine,response |
| R2790 | T5737 | T5732 | dobj | response,blocks |
| R2791 | T5718 | T5717 | pobj | binding,by |
| R2792 | T5738 | T5732 | prep | by,blocks |
| R2793 | T5739 | T5738 | pcomp | inhibiting,by |
| R2794 | T5719 | T5718 | prep | to,binding |
| R2795 | T5740 | T5741 | det | the,CD28 |
| R2796 | T5741 | T5739 | dobj | CD28,inhibiting |
| R2797 | T5742 | T5739 | conj | signaling,inhibiting |
| R2798 | T5720 | T5719 | pobj | CD80,to |
| R2799 | T5743 | T5746 | compound | pathway,] |
| R2800 | T5744 | T5746 | nmod | [,] |
| R2801 | T5745 | T5746 | nummod | 24,] |
| R2802 | T5721 | T5720 | cc | and,CD80 |
| R2803 | T5746 | T5742 | dobj | ],signaling |
| R2804 | T5747 | T5746 | punct | ",",] |
| R2805 | T5748 | T5750 | advmod | as,as |
| R2806 | T5722 | T5720 | conj | CD86,CD80 |
| R2807 | T5749 | T5750 | advmod | well,as |
| R2808 | T5750 | T5746 | cc | as,] |
| R2809 | T5751 | T5742 | advmod | indirectly,signaling |
| R2810 | T5723 | T5709 | prep | with,block |
| R2811 | T5752 | T5742 | prep | by,signaling |
| R2812 | T5753 | T5752 | pcomp | downregulating,by |
| R2813 | T5754 | T5755 | det | the,function |
| R2814 | T5724 | T5725 | amod | high,avidity |
| R2815 | T5755 | T5753 | dobj | function,downregulating |
| R2816 | T5756 | T5755 | prep | of,function |
| R2817 | T5757 | T5758 | amod | antigen-presenting,cells |
| R2818 | T5725 | T5726 | compound | avidity,[ |
| R2819 | T5758 | T5756 | pobj | cells,of |
| R2820 | T5759 | T5732 | punct | .,blocks |
| R2821 | T5760 | T5761 | aux | To,elucidate |
| R2822 | T5726 | T5723 | pobj | [,with |
| R2823 | T5761 | T5777 | advcl | elucidate,investigated |
| R2824 | T5727 | T5728 | nummod | 23,] |
| R2825 | T5762 | T5763 | det | the,resistance |
| R2826 | T5728 | T5726 | appos | ],[ |
| R2827 | T5763 | T5761 | dobj | resistance,elucidate |
| R2828 | T5764 | T5763 | prep | of,resistance |
| R2829 | T5806 | T5805 | prep | of,expression |
| R2830 | T5765 | T5768 | nummod | CD4,cells |
| R2831 | T5766 | T5768 | nummod | +,cells |
| R2832 | T5767 | T5768 | compound | T,cells |
| R2833 | T5768 | T5764 | pobj | cells,of |
| R2834 | T5769 | T5761 | prep | to,elucidate |
| R2835 | T5807 | T5806 | pobj | SOCS1,of |
| R2836 | T5770 | T5772 | det | this,inhibition |
| R2837 | T5771 | T5772 | amod | direct,inhibition |
| R2838 | T5772 | T5769 | pobj | inhibition,to |
| R2839 | T5773 | T5772 | prep | in,inhibition |
| R2840 | T5808 | T5807 | cc | and,SOCS1 |
| R2841 | T5774 | T5773 | pobj | RA,in |
| R2842 | T5775 | T5777 | punct | ",",investigated |
| R2843 | T5776 | T5777 | nsubj | we,investigated |
| R2844 | T5777 | T5777 | ROOT | investigated,investigated |
| R2845 | T5778 | T5779 | det | the,production |
| R2846 | T5779 | T5777 | dobj | production,investigated |
| R2847 | T5809 | T5807 | conj | SOCS3,SOCS1 |
| R2848 | T5780 | T5779 | prep | of,production |
| R2849 | T5781 | T5780 | pobj | IFN-γ,of |
| R2850 | T5782 | T5777 | prep | after,investigated |
| R2851 | T5810 | T5805 | appos | mRNA,expression |
| R2852 | T5783 | T5786 | nsubj | CD3,costimulation |
| R2853 | T5784 | T5783 | cc | and,CD3 |
| R2854 | T5785 | T5783 | conj | CD28,CD3 |
| R2855 | T5786 | T5782 | pobj | costimulation,after |
| R2856 | T5811 | T5799 | prep | in,phosphorylation |
| R2857 | T5787 | T5786 | prep | in,costimulation |
| R2858 | T5788 | T5789 | det | the,presence |
| R2859 | T5812 | T5813 | amod | peripheral,blood |
| R2860 | T5789 | T5787 | pobj | presence,in |
| R2861 | T5790 | T5789 | prep | of,presence |
| R2862 | T5791 | T5790 | pobj | IL-10,of |
| R2863 | T5792 | T5791 | punct | ",",IL-10 |
| R2864 | T5813 | T5811 | pobj | blood,in |
| R2865 | T5793 | T5794 | det | the,induction |
| R2866 | T5794 | T5791 | appos | induction,IL-10 |
| R2867 | T5814 | T5815 | punct | (,PB |
| R2868 | T5795 | T5794 | prep | of,induction |
| R2869 | T5796 | T5795 | pobj | STAT1,of |
| R2870 | T5797 | T5796 | cc | and,STAT1 |
| R2871 | T5815 | T5791 | appos | PB,IL-10 |
| R2872 | T5798 | T5799 | nummod | STAT3,phosphorylation |
| R2873 | T5799 | T5796 | conj | phosphorylation,STAT1 |
| R2874 | T5800 | T5799 | prep | by,phosphorylation |
| R2875 | T5816 | T5815 | punct | ),PB |
| R2876 | T5801 | T5800 | pobj | IL-10,by |
| R2877 | T5802 | T5799 | punct | ",",phosphorylation |
| R2878 | T5803 | T5799 | cc | and,phosphorylation |
| R2879 | T5817 | T5820 | nsubj | CD4,cells |
| R2880 | T5804 | T5805 | det | the,expression |
| R2881 | T5805 | T5799 | conj | expression,phosphorylation |
| R2882 | T5818 | T5820 | nummod | +,cells |
| R2883 | T5819 | T5820 | compound | T,cells |
| R2884 | T5820 | T5820 | ROOT | cells,cells |
| R2885 | T5821 | T5820 | prep | from,cells |
| R2887 | T5822 | T5823 | compound | RA,patients |
| R2889 | T5823 | T5821 | pobj | patients,from |
| R2894 | T5824 | T5820 | punct | .,cells |
| R2316 | T5308 | T5307 | punct | ",",factors |
| R2317 | T5309 | T5310 | compound | matrix,proteases |
| R2319 | T5310 | T5307 | conj | proteases,factors |
| R2322 | T5311 | T5310 | punct | ",",proteases |
| R2323 | T5312 | T5313 | amod | nitric,oxide |
| R2324 | T5313 | T5310 | conj | oxide,proteases |
| R2326 | T5314 | T5313 | punct | ",",oxide |
| R2327 | T5315 | T5313 | cc | and,oxide |
| R2328 | T5316 | T5318 | amod | reactive,species |
| R2329 | T5317 | T5318 | compound | oxygen,species |
| R2331 | T5318 | T5313 | conj | species,oxide |
| R2332 | T5319 | T5321 | nmod | [,] |
| R2333 | T5320 | T5321 | nummod | 10,] |
| R2334 | T5321 | T5297 | appos | ],components |
| R2336 | T5322 | T5293 | punct | .,give |
| R2337 | T5323 | T5324 | nsubj | IL-6,is |
| R2339 | T5324 | T5324 | ROOT | is,is |
| R2340 | T5325 | T5327 | det | a,cytokine |
| R2341 | T5326 | T5327 | amod | pleiotropic,cytokine |
| R2343 | T5327 | T5324 | attr | cytokine,is |
| R2344 | T5328 | T5327 | acl | produced,cytokine |
| R2346 | T5329 | T5328 | advmod | substantially,produced |
| R2347 | T5330 | T5328 | agent | by,produced |
| R2348 | T5331 | T5332 | amod | activated,fibroblasts |
| R2350 | T5332 | T5330 | pobj | fibroblasts,by |
| R2351 | T5333 | T5328 | punct | ",",produced |
| R2352 | T5334 | T5327 | cc | and,cytokine |
| R2353 | T5335 | T5337 | poss | its,actions |
| R2355 | T5336 | T5337 | amod | proinflammatory,actions |
| R2356 | T5337 | T5338 | nsubj | actions,include |
| R2358 | T5338 | T5324 | conj | include,is |
| R2359 | T5339 | T5338 | xcomp | simulating,include |
| R2360 | T5340 | T5342 | det | the,response |
| R2362 | T5341 | T5342 | amod | acute-phase,response |
| R2381 | T5354 | T5356 | amod | hematopoietic,cell |
| R2382 | T5355 | T5356 | compound | precursor,cell |
| R2384 | T5356 | T5357 | compound | cell,differentiation |
| R2385 | T5357 | T5351 | conj | differentiation,functions |
| R2386 | T5358 | T5360 | nmod | [,] |
| R2388 | T5359 | T5360 | nummod | 11,] |
| R2389 | T5360 | T5357 | appos | ],differentiation |
| R2390 | T5361 | T5338 | punct | .,include |
| R2392 | T5362 | T5369 | advmod | However,are |
| R2394 | T5363 | T5369 | punct | ",",are |
| R2395 | T5364 | T5365 | amod | anti-inflammatory,cytokines |
| R2396 | T5365 | T5369 | nsubj | cytokines,are |
| R2398 | T5366 | T5365 | cc | and,cytokines |
| R2399 | T5367 | T5368 | compound | cytokine,inhibitors |
| R2400 | T5368 | T5365 | conj | inhibitors,cytokines |
| R2402 | T5369 | T5369 | ROOT | are,are |
| R2403 | T5370 | T5369 | advmod | also,are |
| R2404 | T5371 | T5369 | acomp | present,are |
| R2406 | T5372 | T5371 | prep | in,present |
bionlp-st-ge-2016-test-tees
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3766 | 3401-3408 | Protein | denotes | IL-10R1 |
| T3765 | 3339-3343 | Protein | denotes | IL-1 |
| T3764 | 3329-3334 | Protein | denotes | TNF-α |
| T3763 | 3227-3232 | Protein | denotes | IL-10 |
| T3762 | 3152-3161 | Positive_regulation | denotes | modulated |
| T3761 | 3132-3137 | Protein | denotes | IL-10 |
| T3760 | 2992-3002 | Gene_expression | denotes | expression |
| T3759 | 2841-2849 | Gene_expression | denotes | produced |
| T3758 | 2834-2839 | Protein | denotes | IL-10 |
| T3757 | 2486-2494 | Gene_expression | denotes | produced |
| T3756 | 2455-2459 | Protein | denotes | IL-6 |
| T3755 | 2167-2171 | Protein | denotes | IL-1 |
| T3754 | 2156-2161 | Protein | denotes | TNF-α |
| T3753 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T3752 | 1588-1598 | Regulation | denotes | regulating |
| T3751 | 1588-1598 | Regulation | denotes | regulating |
| T3750 | 1692-1696 | Protein | denotes | IL-6 |
| T3749 | 1664-1669 | Protein | denotes | STAT3 |
| T3748 | 1633-1637 | Protein | denotes | IL-6 |
| T3747 | 1623-1628 | Protein | denotes | IL-10 |
| T3746 | 1562-1567 | Protein | denotes | SOCS3 |
| T3745 | 1349-1359 | Negative_regulation | denotes | inhibitors |
| T3744 | 1338-1348 | Protein | denotes | JAK kinase |
| T3743 | 1256-1290 | Protein | denotes | cytokine signaling (SOCS) proteins |
| T3742 | 1054-1064 | Positive_regulation | denotes | activation |
| T3741 | 1017-1026 | Negative_regulation | denotes | deficient |
| T3740 | 1082-1087 | Protein | denotes | IL-10 |
| T3739 | 1048-1053 | Protein | denotes | STAT3 |
| T3738 | 1011-1016 | Protein | denotes | STAT3 |
| T3737 | 869-874 | Protein | denotes | STAT3 |
| T3736 | 792-803 | Localization | denotes | translocate |
| T3735 | 792-803 | Localization | denotes | translocate |
| T3734 | 813-820 | Entity | denotes | nucleus |
| T3733 | 709-724 | Phosphorylation | denotes | phosphorylation |
| T3732 | 709-724 | Phosphorylation | denotes | phosphorylation |
| T3731 | 736-750 | Protein | denotes | STAT3 proteins |
| T3730 | 726-731 | Protein | denotes | STAT1 |
| T3729 | 545-552 | Positive_regulation | denotes | induces |
| T3728 | 582-592 | Positive_regulation | denotes | activation |
| T3727 | 553-561 | Entity | denotes | tyrosine |
| T3726 | 600-630 | Protein | denotes | latent transcriptional factors |
| T3725 | 539-544 | Protein | denotes | IL-10 |
| T3724 | 506-519 | Protein | denotes | type 2 IL-10R |
| T3723 | 494-501 | Protein | denotes | IL-10R1 |
| T3722 | 447-451 | Protein | denotes | Tyk2 |
| T3721 | 438-442 | Protein | denotes | Jak1 |
| T3720 | 414-437 | Protein | denotes | family tyrosine kinases |
| T3719 | 409-412 | Protein | denotes | JAK |
| T3718 | 395-407 | Protein | denotes | Janus kinase |
| T3717 | 376-382 | Protein | denotes | IL-10R |
| T3716 | 366-371 | Protein | denotes | IL-10 |
| T3715 | 251-265 | Binding | denotes | ligand-binding |
| T3714 | 251-265 | Binding | denotes | ligand-binding |
| T3713 | 160-165 | Binding | denotes | binds |
| T3712 | 160-165 | Binding | denotes | binds |
| T3711 | 160-165 | Binding | denotes | binds |
| T3710 | 291-298 | Protein | denotes | IL-10R1 |
| T3709 | 276-289 | Protein | denotes | type 1 IL-10R |
| T3708 | 189-195 | Protein | denotes | IL-10R |
| T3707 | 173-187 | Protein | denotes | IL-10 receptor |
| T3706 | 154-159 | Protein | denotes | IL-10 |
| T3705 | 13-18 | Protein | denotes | IL-10 |
| T3834 | 5114-5119 | Positive_regulation | denotes | after |
| T3833 | 5114-5119 | Positive_regulation | denotes | after |
| T3832 | 5077-5089 | Positive_regulation | denotes | investigated |
| T3831 | 5077-5089 | Positive_regulation | denotes | investigated |
| T3830 | 5077-5089 | Positive_regulation | denotes | investigated |
| T3829 | 5077-5089 | Positive_regulation | denotes | investigated |
| T3828 | 5240-5250 | Gene_expression | denotes | expression |
| T3827 | 5240-5250 | Gene_expression | denotes | expression |
| T3826 | 5206-5221 | Phosphorylation | denotes | phosphorylation |
| T3825 | 5206-5221 | Phosphorylation | denotes | phosphorylation |
| T3824 | 5177-5186 | Positive_regulation | denotes | induction |
| T3823 | 5177-5186 | Positive_regulation | denotes | induction |
| T3822 | 5133-5146 | Positive_regulation | denotes | costimulation |
| T3821 | 5133-5146 | Positive_regulation | denotes | costimulation |
| T3820 | 5094-5104 | Gene_expression | denotes | production |
| T3819 | 5264-5274 | Protein | denotes | SOCS3 mRNA |
| T3818 | 5254-5259 | Protein | denotes | SOCS1 |
| T3817 | 5225-5230 | Protein | denotes | IL-10 |
| T3816 | 5200-5205 | Protein | denotes | STAT3 |
| T3815 | 5190-5195 | Protein | denotes | STAT1 |
| T3814 | 5166-5171 | Protein | denotes | IL-10 |
| T3813 | 5128-5132 | Protein | denotes | CD28 |
| T3812 | 5120-5123 | Protein | denotes | CD3 |
| T3811 | 5108-5113 | Protein | denotes | IFN-γ |
| T3810 | 5028-5032 | Protein | denotes | CD4+ |
| T3809 | 4886-4890 | Protein | denotes | CD28 |
| T3808 | 4797-4802 | Protein | denotes | IL-10 |
| T3807 | 4705-4710 | Negative_regulation | denotes | block |
| T3806 | 4705-4710 | Negative_regulation | denotes | block |
| T3805 | 4748-4755 | Binding | denotes | binding |
| T3804 | 4748-4755 | Binding | denotes | binding |
| T3803 | 4715-4725 | Binding | denotes | engagement |
| T3802 | 4768-4772 | Protein | denotes | CD86 |
| T3801 | 4759-4763 | Protein | denotes | CD80 |
| T3800 | 4729-4733 | Protein | denotes | CD28 |
| T3799 | 4690-4693 | Protein | denotes | IgG |
| T3798 | 4379-4389 | Gene_expression | denotes | production |
| T3797 | 4416-4433 | Protein | denotes | rheumatoid factor |
| T3796 | 4343-4347 | Protein | denotes | CD4+ |
| T3795 | 4237-4244 | Localization | denotes | release |
| T3794 | 4237-4244 | Localization | denotes | release |
| T3793 | 4304-4307 | Protein | denotes | IFN |
| T3792 | 4286-4302 | Protein | denotes | interferon gamma |
| T3791 | 4216-4220 | Protein | denotes | CD11 |
| T3790 | 4207-4211 | Protein | denotes | CD69 |
| T3789 | 4026-4029 | Protein | denotes | CD4 |
| T3788 | 3885-3895 | Gene_expression | denotes | expression |
| T3787 | 3885-3895 | Gene_expression | denotes | expression |
| T3786 | 3885-3895 | Gene_expression | denotes | expression |
| T3785 | 3885-3895 | Gene_expression | denotes | expression |
| T3784 | 3744-3751 | Binding | denotes | linkage |
| T3783 | 3744-3751 | Binding | denotes | linkage |
| T3782 | 3744-3751 | Binding | denotes | linkage |
| T3781 | 3954-3958 | Protein | denotes | CD86 |
| T3780 | 3945-3949 | Protein | denotes | CD80 |
| T3779 | 3931-3943 | Protein | denotes | CD28 ligands |
| T3778 | 3899-3921 | Protein | denotes | MHC class II molecules |
| T3777 | 3803-3807 | Protein | denotes | DRB1 |
| T3776 | 3799-3802 | Protein | denotes | HLA |
| T3775 | 3785-3789 | Protein | denotes | DRB1 |
| T3774 | 3781-3784 | Protein | denotes | HLA |
| T3773 | 3759-3780 | Protein | denotes | MHC class II antigens |
| T3772 | 3628-3632 | Protein | denotes | CD28 |
| T3771 | 3551-3555 | Protein | denotes | CD4+ |
| T3770 | 3412-3421 | Negative_regulation | denotes | decreased |
| T3769 | 3387-3397 | Gene_expression | denotes | expression |
| T3768 | 3486-3490 | Protein | denotes | IL-1 |
| T3767 | 3479-3484 | Protein | denotes | TNF-α |
| T3838 | 5177-5186 | Positive_regulation | denotes | induction |
| T3837 | 5177-5186 | Positive_regulation | denotes | induction |
| T3836 | 5114-5119 | Positive_regulation | denotes | after |
| T3835 | 5114-5119 | Positive_regulation | denotes | after |
| R958 | T3706 | T3711 | themeOf | IL-10,binds |
| R959 | T3706 | T3712 | themeOf | IL-10,binds |
| R960 | T3706 | T3713 | themeOf | IL-10,binds |
| R961 | T3707 | T3712 | themeOf | IL-10 receptor,binds |
| R962 | T3708 | T3713 | themeOf | IL-10R,binds |
| R963 | T3709 | T3714 | themeOf | type 1 IL-10R,ligand-binding |
| R964 | T3710 | T3715 | themeOf | IL-10R1,ligand-binding |
| R965 | T3725 | T3729 | causeOf | IL-10,induces |
| R966 | T3726 | T3728 | themeOf | latent transcriptional factors,activation |
| R967 | T3726 | T3727 | partOf | latent transcriptional factors,tyrosine |
| R968 | T3728 | T3729 | themeOf | activation,induces |
| R969 | T3730 | T3732 | themeOf | STAT1,phosphorylation |
| R970 | T3730 | T3735 | themeOf | STAT1,translocate |
| R971 | T3731 | T3733 | themeOf | STAT3 proteins,phosphorylation |
| R972 | T3731 | T3736 | themeOf | STAT3 proteins,translocate |
| R973 | T3734 | T3735 | locationOf | nucleus,translocate |
| R974 | T3734 | T3736 | locationOf | nucleus,translocate |
| R975 | T3738 | T3741 | themeOf | STAT3,deficient |
| R976 | T3739 | T3742 | themeOf | STAT3,activation |
| R977 | T3744 | T3745 | themeOf | JAK kinase,inhibitors |
| R978 | T3747 | T3751 | themeOf | IL-10,regulating |
| R979 | T3748 | T3752 | themeOf | IL-6,regulating |
| R980 | T3756 | T3757 | themeOf | IL-6,produced |
| R981 | T3758 | T3759 | themeOf | IL-10,produced |
| R982 | T3758 | T3760 | themeOf | IL-10,expression |
| R983 | T3761 | T3762 | themeOf | IL-10,modulated |
| R984 | T3766 | T3769 | themeOf | IL-10R1,expression |
| R985 | T3769 | T3770 | themeOf | expression,decreased |
| R986 | T3773 | T3782 | themeOf | MHC class II antigens,linkage |
| R987 | T3773 | T3783 | themeOf | MHC class II antigens,linkage |
| R988 | T3777 | T3784 | themeOf | DRB1,linkage |
| R989 | T3778 | T3785 | themeOf | MHC class II molecules,expression |
| R990 | T3779 | T3782 | themeOf | CD28 ligands,linkage |
| R991 | T3779 | T3784 | themeOf | CD28 ligands,linkage |
| R992 | T3779 | T3786 | themeOf | CD28 ligands,expression |
| R993 | T3780 | T3787 | themeOf | CD80,expression |
| R994 | T3781 | T3783 | themeOf | CD86,linkage |
| R995 | T3781 | T3788 | themeOf | CD86,expression |
| R996 | T3792 | T3794 | themeOf | interferon gamma,release |
| R997 | T3793 | T3795 | themeOf | IFN,release |
| R998 | T3797 | T3798 | themeOf | rheumatoid factor,production |
| R999 | T3800 | T3803 | themeOf | CD28,engagement |
| R1000 | T3801 | T3804 | themeOf | CD80,binding |
| R1001 | T3802 | T3805 | themeOf | CD86,binding |
| R1002 | T3803 | T3806 | themeOf | engagement,block |
| R1004 | T3804 | T3806 | causeOf | binding,block |
| R1003 | T3803 | T3807 | themeOf | engagement,block |
| R1005 | T3805 | T3807 | causeOf | binding,block |
| R1006 | T3811 | T3820 | themeOf | IFN-γ,production |
| R1007 | T3813 | T3821 | themeOf | CD28,costimulation |
| R1008 | T3815 | T3823 | themeOf | STAT1,induction |
| R1009 | T3815 | T3825 | themeOf | STAT1,phosphorylation |
| R1010 | T3816 | T3824 | themeOf | STAT3,induction |
| R1011 | T3816 | T3826 | themeOf | STAT3,phosphorylation |
| R1012 | T3817 | T3823 | causeOf | IL-10,induction |
| R1013 | T3817 | T3824 | causeOf | IL-10,induction |
| R1014 | T3817 | T3837 | causeOf | IL-10,induction |
| R1015 | T3817 | T3838 | causeOf | IL-10,induction |
| R1016 | T3818 | T3827 | themeOf | SOCS1,expression |
| R1017 | T3819 | T3828 | themeOf | SOCS3 mRNA,expression |
| R1018 | T3820 | T3822 | themeOf | production,costimulation |
| R1019 | T3821 | T3833 | themeOf | costimulation,after |
| R1020 | T3822 | T3834 | themeOf | costimulation,after |
| R1021 | T3823 | T3829 | themeOf | induction,investigated |
| R1022 | T3824 | T3830 | themeOf | induction,investigated |
| R1023 | T3825 | T3835 | themeOf | phosphorylation,after |
| R1024 | T3825 | T3837 | themeOf | phosphorylation,induction |
| R1025 | T3826 | T3836 | themeOf | phosphorylation,after |
| R1026 | T3826 | T3838 | themeOf | phosphorylation,induction |
| R1027 | T3827 | T3831 | themeOf | expression,investigated |
| R1028 | T3828 | T3832 | themeOf | expression,investigated |
test3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2413 | 5028-5031 | Protein | denotes | CD4 |
| T2412 | 4886-4890 | Protein | denotes | CD28 |
| T2411 | 4797-4802 | Protein | denotes | IL-10 |
| T2410 | 4768-4772 | Protein | denotes | CD86 |
| T2409 | 4759-4763 | Protein | denotes | CD80 |
| T2408 | 4748-4755 | Binding | denotes | binding |
| T2407 | 4729-4733 | Protein | denotes | CD28 |
| T2406 | 4715-4725 | Binding | denotes | engagement |
| T2405 | 4705-4710 | Negative_regulation | denotes | block |
| T2404 | 4644-4693 | Protein | denotes | cytotoxic T-cell-associated antigen 4 (CD152)-IgG |
| T2403 | 4343-4346 | Protein | denotes | CD4 |
| T2402 | 4315-4320 | Protein | denotes | IL-17 |
| T2401 | 4303-4310 | Protein | denotes | (IFN)-γ |
| T2400 | 4286-4302 | Protein | denotes | interferon gamma |
| T2399 | 4216-4220 | Protein | denotes | CD11 |
| T2398 | 4207-4211 | Protein | denotes | CD69 |
| T2397 | 4026-4029 | Protein | denotes | CD4 |
| T2396 | 3954-3958 | Protein | denotes | CD86 |
| T2395 | 3945-3949 | Protein | denotes | CD80 |
| T2394 | 3931-3935 | Protein | denotes | CD28 |
| T2393 | 3885-3895 | Gene_expression | denotes | expression |
| T2392 | 3799-3812 | Protein | denotes | HLA-DRB1*0401 |
| T2391 | 3781-3794 | Protein | denotes | HLA-DRB1*0404 |
| T2390 | 3628-3632 | Protein | denotes | CD28 |
| T2389 | 3551-3554 | Protein | denotes | CD4 |
| T2388 | 3496-3544 | Protein | denotes | granulocyte–macrophage colony-stimulating factor |
| T2387 | 3486-3490 | Protein | denotes | IL-1 |
| T2386 | 3479-3484 | Protein | denotes | TNF-α |
| T2385 | 3456-3459 | Positive_regulation | denotes | due |
| T2384 | 3412-3421 | Negative_regulation | denotes | decreased |
| T2383 | 3401-3408 | Protein | denotes | IL-10R1 |
| T2382 | 3387-3397 | Gene_expression | denotes | expression |
| T2381 | 3339-3343 | Protein | denotes | IL-1 |
| T2380 | 3329-3334 | Protein | denotes | TNF-α |
| T2379 | 3246-3254 | Negative_regulation | denotes | impaired |
| T2378 | 3227-3232 | Protein | denotes | IL-10 |
| T2377 | 3132-3137 | Protein | denotes | IL-10 |
| T2376 | 2841-2849 | Gene_expression | denotes | produced |
| T2375 | 2834-2839 | Protein | denotes | IL-10 |
| T2374 | 2465-2485 | Protein | denotes | pleiotropic cytokine |
| T2373 | 2455-2459 | Protein | denotes | IL-6 |
| T2372 | 2167-2171 | Protein | denotes | IL-1 |
| T2371 | 2156-2161 | Protein | denotes | TNF-α |
| T2370 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T2369 | 1721-1726 | Protein | denotes | IL-10 |
| T2368 | 1710-1717 | Positive_regulation | denotes | induced |
| T2367 | 1692-1696 | Protein | denotes | IL-6 |
| T2366 | 1681-1688 | Positive_regulation | denotes | induced |
| T2365 | 1670-1680 | Positive_regulation | denotes | activation |
| T2364 | 1664-1669 | Protein | denotes | STAT3 |
| T2363 | 1655-1663 | Negative_regulation | denotes | blocking |
| T2362 | 1633-1637 | Protein | denotes | IL-6 |
| T2361 | 1623-1628 | Protein | denotes | IL-10 |
| T2360 | 1588-1598 | Regulation | denotes | regulating |
| T2359 | 1580-1584 | Regulation | denotes | role |
| T2358 | 1562-1567 | Protein | denotes | SOCS3 |
| T2357 | 1184-1188 | Protein | denotes | IL-6 |
| T2356 | 1082-1087 | Protein | denotes | IL-10 |
| T2355 | 1054-1064 | Positive_regulation | denotes | activation |
| T2354 | 1048-1053 | Protein | denotes | STAT3 |
| T2353 | 1017-1026 | Negative_regulation | denotes | deficient |
| T2352 | 1011-1016 | Protein | denotes | STAT3 |
| T2351 | 937-941 | Protein | denotes | IL-6 |
| T2350 | 901-906 | Protein | denotes | IL-10 |
| T2349 | 869-874 | Protein | denotes | STAT3 |
| T2348 | 792-803 | Localization | denotes | translocate |
| T2347 | 736-741 | Protein | denotes | STAT3 |
| T2346 | 726-731 | Protein | denotes | STAT1 |
| T2345 | 709-724 | Phosphorylation | denotes | phosphorylation |
| T2344 | 693-698 | Protein | denotes | STAT1 |
| T2343 | 631-688 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
| T2342 | 582-592 | Positive_regulation | denotes | activation |
| T2341 | 562-577 | Phosphorylation | denotes | phosphorylation |
| T2340 | 545-552 | Positive_regulation | denotes | induces |
| T2339 | 539-544 | Protein | denotes | IL-10 |
| T2338 | 506-519 | Protein | denotes | type 2 IL-10R |
| T2337 | 494-501 | Protein | denotes | IL-10R1 |
| T2336 | 478-488 | Binding | denotes | associated |
| T2335 | 447-451 | Protein | denotes | Tyk2 |
| T2334 | 438-442 | Protein | denotes | Jak1 |
| T2333 | 383-390 | Binding | denotes | engages |
| T2332 | 376-382 | Protein | denotes | IL-10R |
| T2331 | 366-371 | Protein | denotes | IL-10 |
| T2330 | 351-362 | Binding | denotes | interaction |
| T2329 | 328-341 | Protein | denotes | type 2 IL-10R |
| T2328 | 291-298 | Protein | denotes | IL-10R1 |
| T2327 | 276-289 | Protein | denotes | type 1 IL-10R |
| T2326 | 258-265 | Binding | denotes | binding |
| T2325 | 189-195 | Protein | denotes | IL-10R |
| T2324 | 173-187 | Protein | denotes | IL-10 receptor |
| T2323 | 160-165 | Binding | denotes | binds |
| T2322 | 154-159 | Protein | denotes | IL-10 |
| T2321 | 4886-4890 | Protein | denotes | CD28 |
| T2320 | 4797-4802 | Protein | denotes | IL-10 |
| T2319 | 4768-4772 | Protein | denotes | CD86 |
| T2318 | 4759-4763 | Protein | denotes | CD80 |
| T2317 | 4729-4733 | Protein | denotes | CD28 |
| T2316 | 4644-4693 | Protein | denotes | cytotoxic T-cell-associated antigen 4 (CD152)-IgG |
| T2315 | 4343-4346 | Protein | denotes | CD4 |
| T2314 | 4315-4320 | Protein | denotes | IL-17 |
| T2313 | 4303-4310 | Protein | denotes | (IFN)-γ |
| T2312 | 4286-4302 | Protein | denotes | interferon gamma |
| T2311 | 4216-4220 | Protein | denotes | CD11 |
| T2310 | 4207-4211 | Protein | denotes | CD69 |
| T2309 | 4026-4029 | Protein | denotes | CD4 |
| T2308 | 3954-3958 | Protein | denotes | CD86 |
| T2307 | 3945-3949 | Protein | denotes | CD80 |
| T2306 | 3931-3935 | Protein | denotes | CD28 |
| T2305 | 3799-3812 | Protein | denotes | HLA-DRB1*0401 |
| T2304 | 3781-3794 | Protein | denotes | HLA-DRB1*0404 |
| T2303 | 3628-3632 | Protein | denotes | CD28 |
| T2302 | 3551-3554 | Protein | denotes | CD4 |
| T2301 | 3496-3544 | Protein | denotes | granulocyte–macrophage colony-stimulating factor |
| T2300 | 3486-3490 | Protein | denotes | IL-1 |
| T2299 | 3479-3484 | Protein | denotes | TNF-α |
| T2298 | 3401-3408 | Protein | denotes | IL-10R1 |
| T2297 | 3339-3343 | Protein | denotes | IL-1 |
| T2296 | 3329-3334 | Protein | denotes | TNF-α |
| T2295 | 3227-3232 | Protein | denotes | IL-10 |
| T2294 | 3132-3137 | Protein | denotes | IL-10 |
| T2293 | 2834-2839 | Protein | denotes | IL-10 |
| T2292 | 2465-2485 | Protein | denotes | pleiotropic cytokine |
| T2291 | 2455-2459 | Protein | denotes | IL-6 |
| T2290 | 2167-2171 | Protein | denotes | IL-1 |
| T2289 | 2156-2161 | Protein | denotes | TNF-α |
| T2288 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T2287 | 1721-1726 | Protein | denotes | IL-10 |
| T2286 | 1692-1696 | Protein | denotes | IL-6 |
| T2285 | 1664-1669 | Protein | denotes | STAT3 |
| T2284 | 1633-1637 | Protein | denotes | IL-6 |
| T2283 | 1623-1628 | Protein | denotes | IL-10 |
| T2282 | 1562-1567 | Protein | denotes | SOCS3 |
| T2281 | 1184-1188 | Protein | denotes | IL-6 |
| T2280 | 1082-1087 | Protein | denotes | IL-10 |
| T2279 | 1048-1053 | Protein | denotes | STAT3 |
| T2278 | 1011-1016 | Protein | denotes | STAT3 |
| T2277 | 937-941 | Protein | denotes | IL-6 |
| T2276 | 901-906 | Protein | denotes | IL-10 |
| T2275 | 869-874 | Protein | denotes | STAT3 |
| T2274 | 736-741 | Protein | denotes | STAT3 |
| T2273 | 726-731 | Protein | denotes | STAT1 |
| T2272 | 693-698 | Protein | denotes | STAT1 |
| T2271 | 631-688 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
| T2270 | 539-544 | Protein | denotes | IL-10 |
| T2269 | 506-519 | Protein | denotes | type 2 IL-10R |
| T2268 | 494-501 | Protein | denotes | IL-10R1 |
| T2267 | 447-451 | Protein | denotes | Tyk2 |
| T2266 | 438-442 | Protein | denotes | Jak1 |
| T2265 | 376-382 | Protein | denotes | IL-10R |
| T2264 | 366-371 | Protein | denotes | IL-10 |
| T2263 | 328-341 | Protein | denotes | type 2 IL-10R |
| T2262 | 291-298 | Protein | denotes | IL-10R1 |
| T2261 | 276-289 | Protein | denotes | type 1 IL-10R |
| T2260 | 189-195 | Protein | denotes | IL-10R |
| T2259 | 173-187 | Protein | denotes | IL-10 receptor |
| T2258 | 154-159 | Protein | denotes | IL-10 |
| T2257 | 14-18 | Protein | denotes | L-10 |
| T2256 | 15-18 | Protein | denotes | -10 |
| T2255 | 5300-5303 | Protein | denotes | CD4 |
| T2254 | 5264-5269 | Protein | denotes | SOCS3 |
| T2253 | 5254-5259 | Protein | denotes | SOCS1 |
| T2252 | 5225-5230 | Protein | denotes | IL-10 |
| T2251 | 5200-5205 | Protein | denotes | STAT3 |
| T2250 | 5190-5195 | Protein | denotes | STAT1 |
| T2249 | 5166-5171 | Protein | denotes | IL-10 |
| T2248 | 5128-5132 | Protein | denotes | CD28 |
| T2247 | 5108-5113 | Protein | denotes | IFN-γ |
| T2246 | 5028-5031 | Protein | denotes | CD4 |
| T2426 | 5300-5303 | Protein | denotes | CD4 |
| T2425 | 5264-5269 | Protein | denotes | SOCS3 |
| T2424 | 5254-5259 | Protein | denotes | SOCS1 |
| T2423 | 5240-5250 | Gene_expression | denotes | expression |
| T2422 | 5225-5230 | Protein | denotes | IL-10 |
| T2421 | 5206-5221 | Phosphorylation | denotes | phosphorylation |
| T2420 | 5200-5205 | Protein | denotes | STAT3 |
| T2419 | 5190-5195 | Protein | denotes | STAT1 |
| T2418 | 5177-5186 | Positive_regulation | denotes | induction |
| T2417 | 5166-5171 | Protein | denotes | IL-10 |
| T2416 | 5128-5132 | Protein | denotes | CD28 |
| T2415 | 5108-5113 | Protein | denotes | IFN-γ |
| T2414 | 5094-5104 | Gene_expression | denotes | production |
| R783 | T2335 | T2333 | themeOf | Tyk2,engages |
| R784 | T2337 | T2336 | themeOf | IL-10R1,associated |
| R785 | T2338 | T2336 | themeOf | type 2 IL-10R,associated |
| R786 | T2339 | T2340 | causeOf | IL-10,induces |
| R787 | T2341 | T2340 | themeOf | phosphorylation,induces |
| R788 | T2343 | T2342 | themeOf | signal transducer and activator of transcription (STAT) 3,activation |
| R789 | T2344 | T2342 | themeOf | STAT1,activation |
| R790 | T2346 | T2348 | themeOf | STAT1,translocate |
| R791 | T2346 | T2345 | themeOf | STAT1,phosphorylation |
| R792 | T2347 | T2345 | themeOf | STAT3,phosphorylation |
| R793 | T2347 | T2348 | themeOf | STAT3,translocate |
| R794 | T2352 | T2353 | themeOf | STAT3,deficient |
| R795 | T2354 | T2355 | themeOf | STAT3,activation |
| R796 | T2358 | T2363 | causeOf | SOCS3,blocking |
| R797 | T2358 | T2359 | causeOf | SOCS3,role |
| R798 | T2364 | T2365 | themeOf | STAT3,activation |
| R799 | T2365 | T2366 | themeOf | activation,induced |
| R800 | T2365 | T2363 | themeOf | activation,blocking |
| R801 | T2367 | T2366 | causeOf | IL-6,induced |
| R802 | T2369 | T2368 | causeOf | IL-10,induced |
| R803 | T2371 | T2370 | equivalentTo | TNF-α,Tumor necrosis factor alpha |
| R804 | T2375 | T2376 | themeOf | IL-10,produced |
| R805 | T2382 | T2384 | themeOf | expression,decreased |
| R806 | T2382 | T2385 | themeOf | expression,due |
| R807 | T2383 | T2382 | themeOf | IL-10R1,expression |
| R808 | T2386 | T2385 | causeOf | TNF-α,due |
| R809 | T2387 | T2385 | causeOf | IL-1,due |
| R810 | T2388 | T2384 | causeOf | granulocyte–macrophage colony-stimulating factor,decreased |
| R811 | T2388 | T2385 | causeOf | granulocyte–macrophage colony-stimulating factor,due |
| R812 | T2394 | T2393 | themeOf | CD28,expression |
| R813 | T2395 | T2393 | themeOf | CD80,expression |
| R814 | T2396 | T2393 | themeOf | CD86,expression |
| R815 | T2404 | T2408 | themeOf | cytotoxic T-cell-associated antigen 4 (CD152)-IgG,binding |
| R816 | T2406 | T2405 | themeOf | engagement,block |
| R817 | T2407 | T2406 | themeOf | CD28,engagement |
| R818 | T2407 | T2408 | themeOf | CD28,binding |
| R819 | T2409 | T2408 | themeOf | CD80,binding |
| R820 | T2410 | T2408 | themeOf | CD86,binding |
| R821 | T2415 | T2414 | themeOf | IFN-γ,production |
| R822 | T2416 | T2414 | themeOf | CD28,production |
| R823 | T2419 | T2421 | themeOf | STAT1,phosphorylation |
| R824 | T2420 | T2421 | themeOf | STAT3,phosphorylation |
| R825 | T2421 | T2418 | themeOf | phosphorylation,induction |
| R826 | T2422 | T2418 | causeOf | IL-10,induction |
| R827 | T2424 | T2423 | themeOf | SOCS1,expression |
| R828 | T2425 | T2423 | themeOf | SOCS3,expression |
| R768 | T2322 | T2323 | themeOf | IL-10,binds |
| R769 | T2324 | T2323 | themeOf | IL-10 receptor,binds |
| R770 | T2325 | T2324 | equivalentTo | IL-10R,IL-10 receptor |
| R771 | T2327 | T2326 | themeOf | type 1 IL-10R,binding |
| R772 | T2328 | T2327 | equivalentTo | IL-10R1,type 1 IL-10R |
| R773 | T2329 | T2326 | themeOf | type 2 IL-10R,binding |
| R774 | T2331 | T2333 | themeOf | IL-10,engages |
| R775 | T2331 | T2330 | themeOf | IL-10,interaction |
| R776 | T2331 | T2336 | themeOf | IL-10,associated |
| R777 | T2332 | T2330 | themeOf | IL-10R,interaction |
| R778 | T2334 | T2330 | themeOf | Jak1,interaction |
| R779 | T2334 | T2336 | themeOf | Jak1,associated |
| R780 | T2334 | T2333 | themeOf | Jak1,engages |
| R781 | T2335 | T2336 | themeOf | Tyk2,associated |
| R782 | T2335 | T2330 | themeOf | Tyk2,interaction |
testone
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2128 | 4315-4320 | Protein | denotes | IL-17 |
| T2127 | 4303-4310 | Protein | denotes | (IFN)-γ |
| T2126 | 4286-4302 | Protein | denotes | interferon gamma |
| T2125 | 4216-4220 | Protein | denotes | CD11 |
| T2124 | 4207-4211 | Protein | denotes | CD69 |
| T2123 | 4026-4029 | Protein | denotes | CD4 |
| T2122 | 3954-3958 | Protein | denotes | CD86 |
| T2121 | 3945-3949 | Protein | denotes | CD80 |
| T2120 | 3931-3935 | Protein | denotes | CD28 |
| T2119 | 3799-3812 | Protein | denotes | HLA-DRB1*0401 |
| T2118 | 3781-3794 | Protein | denotes | HLA-DRB1*0404 |
| T2117 | 3628-3632 | Protein | denotes | CD28 |
| T2116 | 3551-3554 | Protein | denotes | CD4 |
| T2115 | 3496-3544 | Protein | denotes | granulocyte–macrophage colony-stimulating factor |
| T2114 | 3486-3490 | Protein | denotes | IL-1 |
| T2113 | 3479-3484 | Protein | denotes | TNF-α |
| T2112 | 3401-3408 | Protein | denotes | IL-10R1 |
| T2111 | 3339-3343 | Protein | denotes | IL-1 |
| T2110 | 1721-1726 | Protein | denotes | IL-10 |
| T2109 | 1692-1696 | Protein | denotes | IL-6 |
| T2108 | 1664-1669 | Protein | denotes | STAT3 |
| T2107 | 1633-1637 | Protein | denotes | IL-6 |
| T2106 | 1623-1628 | Protein | denotes | IL-10 |
| T2105 | 1562-1567 | Protein | denotes | SOCS3 |
| T2104 | 1184-1188 | Protein | denotes | IL-6 |
| T2103 | 1082-1087 | Protein | denotes | IL-10 |
| T2102 | 1048-1053 | Protein | denotes | STAT3 |
| T2101 | 1011-1016 | Protein | denotes | STAT3 |
| T2100 | 937-941 | Protein | denotes | IL-6 |
| T2099 | 901-906 | Protein | denotes | IL-10 |
| T2098 | 869-874 | Protein | denotes | STAT3 |
| T2097 | 736-741 | Protein | denotes | STAT3 |
| T2096 | 726-731 | Protein | denotes | STAT1 |
| T2095 | 693-698 | Protein | denotes | STAT1 |
| T2094 | 631-688 | Protein | denotes | signal transducer and activator of transcription (STAT) 3 |
| T2093 | 3329-3334 | Protein | denotes | TNF-α |
| T2092 | 3227-3232 | Protein | denotes | IL-10 |
| T2091 | 3132-3137 | Protein | denotes | IL-10 |
| T2090 | 2834-2839 | Protein | denotes | IL-10 |
| T2089 | 2465-2485 | Protein | denotes | pleiotropic cytokine |
| T2088 | 2455-2459 | Protein | denotes | IL-6 |
| T2087 | 2167-2171 | Protein | denotes | IL-1 |
| T2086 | 2156-2161 | Protein | denotes | TNF-α |
| T2085 | 2127-2154 | Protein | denotes | Tumor necrosis factor alpha |
| T2084 | 539-544 | Protein | denotes | IL-10 |
| T2083 | 506-519 | Protein | denotes | type 2 IL-10R |
| T2082 | 494-501 | Protein | denotes | IL-10R1 |
| T2081 | 447-451 | Protein | denotes | Tyk2 |
| T2080 | 438-442 | Protein | denotes | Jak1 |
| T2079 | 376-382 | Protein | denotes | IL-10R |
| T2078 | 366-371 | Protein | denotes | IL-10 |
| T2077 | 328-341 | Protein | denotes | type 2 IL-10R |
| T2076 | 291-298 | Protein | denotes | IL-10R1 |
| T2075 | 276-289 | Protein | denotes | type 1 IL-10R |
| T2074 | 189-195 | Protein | denotes | IL-10R |
| T2073 | 173-187 | Protein | denotes | IL-10 receptor |
| T2072 | 154-159 | Protein | denotes | IL-10 |
| T2071 | 14-18 | Protein | denotes | L-10 |
| T2174 | 5240-5250 | Gene_expression | denotes | expression |
| T2173 | 5206-5221 | Phosphorylation | denotes | phosphorylation |
| T2172 | 5177-5186 | Positive_regulation | denotes | induction |
| T2171 | 5094-5104 | Gene_expression | denotes | production |
| T2170 | 4748-4755 | Binding | denotes | binding |
| T2169 | 4715-4725 | Binding | denotes | engagement |
| T2168 | 4705-4710 | Negative_regulation | denotes | block |
| T2167 | 3885-3895 | Gene_expression | denotes | expression |
| T2166 | 3412-3421 | Negative_regulation | denotes | decreased |
| T2165 | 3387-3397 | Gene_expression | denotes | expression |
| T2164 | 3246-3254 | Negative_regulation | denotes | impaired |
| T2163 | 2992-3002 | Gene_expression | denotes | expression |
| T2162 | 2841-2849 | Gene_expression | denotes | produced |
| T2161 | 1710-1717 | Positive_regulation | denotes | induced |
| T2160 | 1681-1688 | Positive_regulation | denotes | induced |
| T2159 | 1670-1680 | Positive_regulation | denotes | activation |
| T2158 | 1655-1663 | Negative_regulation | denotes | blocking |
| T2157 | 1588-1598 | Regulation | denotes | regulating |
| T2156 | 1054-1064 | Positive_regulation | denotes | activation |
| T2155 | 1017-1026 | Negative_regulation | denotes | deficient |
| T2154 | 813-820 | Entity | denotes | nucleus |
| T2153 | 792-803 | Localization | denotes | translocate |
| T2152 | 709-724 | Phosphorylation | denotes | phosphorylation |
| T2151 | 562-577 | Phosphorylation | denotes | phosphorylation |
| T2150 | 545-552 | Positive_regulation | denotes | induces |
| T2149 | 478-488 | Binding | denotes | associated |
| T2148 | 383-390 | Binding | denotes | engages |
| T2147 | 351-362 | Binding | denotes | interaction |
| T2146 | 160-165 | Binding | denotes | binds |
| T2145 | 5300-5303 | Protein | denotes | CD4 |
| T2144 | 5264-5269 | Protein | denotes | SOCS3 |
| T2143 | 5254-5259 | Protein | denotes | SOCS1 |
| T2142 | 5225-5230 | Protein | denotes | IL-10 |
| T2141 | 5200-5205 | Protein | denotes | STAT3 |
| T2140 | 5190-5195 | Protein | denotes | STAT1 |
| T2139 | 5166-5171 | Protein | denotes | IL-10 |
| T2138 | 5128-5132 | Protein | denotes | CD28 |
| T2137 | 5108-5113 | Protein | denotes | IFN-γ |
| T2136 | 5028-5031 | Protein | denotes | CD4 |
| T2135 | 4886-4890 | Protein | denotes | CD28 |
| T2134 | 4797-4802 | Protein | denotes | IL-10 |
| T2133 | 4768-4772 | Protein | denotes | CD86 |
| T2132 | 4759-4763 | Protein | denotes | CD80 |
| T2131 | 4729-4733 | Protein | denotes | CD28 |
| T2130 | 4644-4693 | Protein | denotes | cytotoxic T-cell-associated antigen 4 (CD152)-IgG |
| T2129 | 4343-4346 | Protein | denotes | CD4 |
| R711 | T2072 | T2146 | themeOf | IL-10,binds |
| R712 | T2073 | T2146 | themeOf | IL-10 receptor,binds |
| R713 | T2074 | T2073 | equivalentTo | IL-10R,IL-10 receptor |
| R714 | T2076 | T2075 | equivalentTo | IL-10R1,type 1 IL-10R |
| R715 | T2078 | T2148 | themeOf | IL-10,engages |
| R716 | T2078 | T2147 | themeOf | IL-10,interaction |
| R717 | T2078 | T2149 | themeOf | IL-10,associated |
| R718 | T2079 | T2148 | themeOf | IL-10R,engages |
| R719 | T2079 | T2147 | themeOf | IL-10R,interaction |
| R720 | T2081 | T2149 | themeOf | Tyk2,associated |
| R721 | T2081 | T2148 | themeOf | Tyk2,engages |
| R722 | T2082 | T2149 | themeOf | IL-10R1,associated |
| R723 | T2083 | T2149 | themeOf | type 2 IL-10R,associated |
| R724 | T2084 | T2150 | causeOf | IL-10,induces |
| R725 | T2086 | T2085 | equivalentTo | TNF-α,Tumor necrosis factor alpha |
| R726 | T2090 | T2163 | themeOf | IL-10,expression |
| R727 | T2090 | T2162 | themeOf | IL-10,produced |
| R728 | T2093 | T2164 | causeOf | TNF-α,impaired |
| R729 | T2096 | T2153 | themeOf | STAT1,translocate |
| R730 | T2096 | T2152 | themeOf | STAT1,phosphorylation |
| R731 | T2097 | T2152 | themeOf | STAT3,phosphorylation |
| R732 | T2097 | T2153 | themeOf | STAT3,translocate |
| R733 | T2101 | T2155 | themeOf | STAT3,deficient |
| R734 | T2102 | T2156 | themeOf | STAT3,activation |
| R735 | T2106 | T2157 | themeOf | IL-10,regulating |
| R736 | T2107 | T2158 | causeOf | IL-6,blocking |
| R737 | T2108 | T2159 | themeOf | STAT3,activation |
| R738 | T2109 | T2160 | causeOf | IL-6,induced |
| R739 | T2109 | T2158 | causeOf | IL-6,blocking |
| R740 | T2110 | T2160 | causeOf | IL-10,induced |
| R741 | T2110 | T2161 | causeOf | IL-10,induced |
| R742 | T2111 | T2164 | causeOf | IL-1,impaired |
| R743 | T2112 | T2165 | themeOf | IL-10R1,expression |
| R744 | T2113 | T2166 | causeOf | TNF-α,decreased |
| R745 | T2114 | T2166 | causeOf | IL-1,decreased |
| R746 | T2115 | T2166 | causeOf | granulocyte–macrophage colony-stimulating factor,decreased |
| R747 | T2121 | T2167 | themeOf | CD80,expression |
| R748 | T2122 | T2167 | themeOf | CD86,expression |
| R749 | T2131 | T2169 | themeOf | CD28,engagement |
| R750 | T2132 | T2170 | themeOf | CD80,binding |
| R751 | T2133 | T2170 | themeOf | CD86,binding |
| R752 | T2137 | T2171 | themeOf | IFN-γ,production |
| R753 | T2138 | T2171 | themeOf | CD28,production |
| R754 | T2140 | T2173 | themeOf | STAT1,phosphorylation |
| R755 | T2141 | T2173 | themeOf | STAT3,phosphorylation |
| R756 | T2142 | T2172 | causeOf | IL-10,induction |
| R757 | T2143 | T2174 | themeOf | SOCS1,expression |
| R758 | T2144 | T2174 | themeOf | SOCS3,expression |
| R759 | T2151 | T2150 | themeOf | phosphorylation,induces |
| R760 | T2154 | T2153 | locationOf | nucleus,translocate |
| R761 | T2159 | T2160 | themeOf | activation,induced |
| R762 | T2159 | T2158 | themeOf | activation,blocking |
| R763 | T2160 | T2158 | themeOf | induced,blocking |
| R764 | T2165 | T2166 | themeOf | expression,decreased |
| R765 | T2169 | T2168 | themeOf | engagement,block |
| R766 | T2170 | T2168 | causeOf | binding,block |
| R767 | T2173 | T2172 | themeOf | phosphorylation,induction |