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PMC:1064873 / 14989-23420 JSONTXT

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LappsTest

Id Subject Object Predicate Lexical cue
T20060 8415-8422 Protein denotes RA CD4+
T20059 8406-8411 Protein denotes SOCS1
T20058 8325-8330 Protein denotes STAT3
T20057 8311-8316 Protein denotes IL-10
T20056 8245-8249 Protein denotes IL-6
T20055 8209-8213 Protein denotes CD4+
T20054 8148-8155 Protein denotes RA CD4+
T20053 8134-8144 Protein denotes SOCS1 mRNA
T20052 8083-8087 Protein denotes CD4+
T20051 8048-8065 Protein denotes SOCS3 transcripts
T20050 8022-8027 Protein denotes SOCS1
T20049 7979-7986 Protein denotes RA CD4+
T20048 7860-7867 Protein denotes PB CD4+
T20047 7835-7845 Protein denotes SOCS3 mRNA
T20046 7825-7830 Protein denotes SOCS1
T20045 7794-7801 Protein denotes RA CD4+
T20044 7774-7779 Protein denotes STAT3
T20043 7723-7728 Protein denotes SOCSs
T20042 7679-7684 Protein denotes STAT1
T20041 7664-7668 Protein denotes IFN-
T20040 7612-7617 Protein denotes STAT3
T20039 7597-7602 Protein denotes IL-10
T20038 7562-7567 Protein denotes SOCS1
T20037 7523-7527 Protein denotes IL-6
T20036 7473-7478 Protein denotes IL-10
T20035 7457-7461 Protein denotes IL-6
T20034 7429-7434 Protein denotes STAT3
T20033 7375-7380 Protein denotes SOCS3
T20032 7193-7207 Protein denotes SOCS3 proteins
T20031 7183-7188 Protein denotes SOCS1
T20030 7177-7181 Protein denotes JAKs
T20029 7123-7143 Protein denotes RA CD4+ T cells IL-6
T20028 7109-7119 Protein denotes SOCS1 mRNA
T17298 6300-6305 Protein denotes STAT1
T17297 6260-6265 Protein denotes STAT3
T17296 6226-6231 Protein denotes STAT1
T17295 6201-6205 Protein denotes IL-6
T17294 6128-6133 Protein denotes STAT1
T17293 6042-6074 Protein denotes dominant STAT3-activating factor
T17292 6030-6034 Protein denotes IL-6
T17291 5977-5981 Protein denotes IL-6
T17290 5918-5923 Protein denotes STAT3
T17289 5902-5907 Protein denotes STAT1
T17288 5888-5893 Protein denotes STAT3
T17287 5772-5776 Protein denotes STAT
T17286 5715-5746 Protein denotes neutralizing anti-IL-6 antibody
T17285 5602-5606 Protein denotes CD4+
T17284 5519-5523 Protein denotes CD4+
T17283 5504-5508 Protein denotes IL-6
T17282 5465-5470 Protein denotes STAT3
T17281 5455-5460 Protein denotes STAT1
T17280 5419-5424 Protein denotes IL-10
T17279 5384-5389 Protein denotes STAT3
T17278 5318-5322 Protein denotes IL-6
T17277 5279-5283 Protein denotes CD4+
T17276 5144-5148 Protein denotes IL-6
T17275 5105-5110 Protein denotes STAT3
T17274 5019-5023 Protein denotes IL-6
T17273 4924-4947 Protein denotes epidermal growth factor
T17272 4888-4918 Protein denotes platelet-derived growth factor
T17271 4828-4832 Protein denotes IL-6
T17270 4802-4813 Protein denotes IL-6 family
T17269 4734-4739 Protein denotes STAT3
T17268 4721-4725 Protein denotes CD4+
T17267 4698-4703 Protein denotes IL-10
T17266 4658-4663 Protein denotes STAT3
T17265 4644-4648 Protein denotes IL-6
T17311 7072-7079 Protein denotes RA CD4+
T17310 7063-7068 Protein denotes IL-10
T17309 6999-7004 Protein denotes STAT3
T17308 6953-6957 Protein denotes IL-6
T17307 6873-6878 Protein denotes IL-10
T17306 6828-6832 Protein denotes IL-6
T17305 6690-6694 Protein denotes IL-6
T17304 6557-6560 Protein denotes CD3
T17303 6525-6529 Protein denotes CD4+
T17302 6499-6503 Protein denotes IL-6
T17301 6440-6444 Protein denotes CD4+
T17300 6403-6408 Protein denotes IL-10
T17299 6369-6373 Protein denotes IL-6
T15437 3274-3280 Protein denotes IL-10R
T15436 3239-3246 Protein denotes RA CD4+
T15435 3214-3219 Protein denotes STAT3
T15434 3199-3204 Protein denotes IL-10
T15466 4620-4625 Protein denotes STAT3
T15465 4541-4546 Protein denotes STAT3
T15464 4527-4532 Protein denotes IL-10
T15463 4509-4513 Protein denotes CD4+
T15462 4485-4505 Protein denotes IL-10-activated STAT
T15461 4466-4471 Protein denotes STAT3
T15460 4414-4418 Protein denotes CD4+
T15459 4388-4395 Protein denotes RA CD4+
T15458 4339-4344 Protein denotes STAT1
T15457 4325-4330 Protein denotes IL-10
T15456 4276-4286 Protein denotes RA ST CD4+
T15455 4240-4245 Protein denotes STAT3
T15454 4190-4195 Protein denotes STAT3
T15453 4089-4094 Protein denotes STAT3
T15452 4033-4038 Protein denotes STAT3
T15451 3948-3953 Protein denotes STAT3
T15450 3908-3912 Protein denotes CD4+
T15449 3870-3875 Protein denotes IL-10
T15448 3813-3818 Protein denotes STAT3
T15447 3710-3717 Protein denotes PB CD4+
T15446 3701-3706 Protein denotes IL-10
T15445 3676-3681 Protein denotes STAT3
T15444 3666-3671 Protein denotes STAT1
T15443 3622-3627 Protein denotes STAT3
T15442 3456-3461 Protein denotes STAT3
T15441 3397-3422 Protein denotes Macrophage-specific STAT3
T15440 3386-3391 Protein denotes STAT3
T15439 3376-3381 Protein denotes STAT1
T15438 3286-3291 Protein denotes IL-10
T14498 3161-3165 Protein denotes CD4+
T14497 3136-3141 Protein denotes IL-10
T14496 2969-2973 Protein denotes CD4+
T14495 2947-2954 Protein denotes IL-10R1
T14494 2796-2803 Protein denotes PB CD4+
T14493 2785-2792 Protein denotes IL-10R1
T14492 2698-2705 Protein denotes RA CD4+
T14491 2678-2683 Protein denotes IL-10
T14490 2563-2570 Protein denotes IL-10R1
T14489 2508-2515 Protein denotes IL-10R1
T14488 2439-2444 Protein denotes IL-10
T14487 2388-2395 Protein denotes RA CD4+
T12196 1859-1863 Protein denotes IL-2
T12195 1810-1814 Protein denotes CD4+
T12194 1788-1793 Protein denotes IL-10
T12193 1692-1696 Protein denotes CD4+
T12192 1432-1437 Protein denotes IL-10
T12191 1230-1233 Protein denotes CRP
T12190 1173-1176 Protein denotes CRP
T12189 1028-1032 Protein denotes CD4+
T12188 941-946 Protein denotes IL-10
T12187 887-892 Protein denotes IL-10
T12186 794-801 Protein denotes RA CD4+
T12185 708-712 Protein denotes CD4+
T12184 492-544 Protein denotes immobilized anti-CD3 antibody and anti-CD28 antibody
T12183 390-397 Protein denotes PB CD4+
T12182 374-379 Protein denotes IL-10
T12181 355-362 Protein denotes RA CD4+
T12180 285-314 Protein denotes phosphatidylinositol 3-kinase
T12179 240-244 Protein denotes CD28
T12178 184-189 Protein denotes IL-10
T12177 83-109 Protein denotes CD28 costimulatory pathway
T12176 63-70 Protein denotes RA CD4+
T12175 23-28 Protein denotes IL-10
T12201 2308-2313 Protein denotes IL-10
T12200 2234-2241 Protein denotes RA CD4+
T12199 2007-2011 Protein denotes IL-2
T12198 1943-1948 Protein denotes IL-10
T12197 1878-1882 Protein denotes CD4+

2_test

Id Subject Object Predicate Lexical cue
15535835-10898505-4156888 316-318 10898505 denotes 24
15535835-7306232-4156889 1252-1254 7306232 denotes 26
15535835-11244051-4156890 2559-2560 11244051 denotes 1
15535835-11739506-4156891 2636-2638 11739506 denotes 29
15535835-7543512-4156892 3393-3394 7543512 denotes 3
15535835-10023769-4156893 3531-3532 10023769 denotes 5
15535835-14688368-4156894 3644-3646 14688368 denotes 30
15535835-12039028-4156895 4971-4972 12039028 denotes 4
15535835-7869026-4156896 5133-5135 7869026 denotes 31
15535835-9182920-4156897 5231-5233 9182920 denotes 27
15535835-12039028-4156898 5591-5592 12039028 denotes 4
15535835-11527983-4156899 7371-7372 11527983 denotes 7
15535835-12754507-4156900 7539-7540 12754507 denotes 8
15535835-12626585-4156901 7541-7542 12626585 denotes 9
15535835-12538698-4156902 7697-7699 12538698 denotes 32

biosemtest

Id Subject Object Predicate Lexical cue
T20159 8288-8300 UMLS/C0750502 denotes ignificance.
T20158 8203-8209 UMLS/C1551394 denotes ormal
T20157 7882-7888 UMLS/C1547419 denotes ctive
T20156 7282-7286 UMLS/C0331781 denotes play
T20155 7642-7651 UMLS/C0871261 denotes responses
T20154 8076-8083 UMLS/C1882979 denotes ontrol
T20153 7918-7926 UMLS/C1882979 denotes ontrols
T20152 8262-8272 UMLS/C1521721 denotes upporting
T20151 8383-8387 UMLS/C1292711 denotes art
T20349 8033-8038 UMLS/C0234886 denotes ower
T20348 7996-8005 UMLS/C1549781 denotes ontained
T20347 8277-8287 UMLS/C0205245 denotes unctional
T20346 8203-8209 UMLS/C2347086 denotes ormal
T20345 7313-7323 UMLS/C1628982 denotes inhibition
T20344 8326-8331 UMLS/C1367307 denotes TAT3
T20343 7775-7780 UMLS/C1367307 denotes TAT3
T20342 7612-7617 UMLS/C1367307 denotes STAT3
T20341 7429-7434 UMLS/C1367307 denotes STAT3
T20340 8203-8209 UMLS/C0439166 denotes ormal
T20339 7361-7369 UMLS/C1704259 denotes pathways
T20338 8076-8083 UMLS/C0243148 denotes ontrol
T20337 7918-7926 UMLS/C0243148 denotes ontrols
T20336 7680-7685 UP/P42224 denotes TAT1
T20335 8277-8287 UMLS/C0542341 denotes unctional
T20334 7642-7651 UMLS/C1706817 denotes responses
T20333 7152-7155 UMLS/C0205448 denotes two
T20332 7892-7900 UMLS/C1550655 denotes atients
T20331 8076-8083 UMLS/C1547100 denotes ontrol
T20330 7918-7926 UMLS/C1547100 denotes ontrols
T20329 7295-7299 UMLS/C1704326 denotes role
T20328 8326-8331 UMLS/C0253050 denotes TAT3
T20327 7775-7780 UMLS/C0253050 denotes TAT3
T20326 7612-7617 UMLS/C0253050 denotes STAT3
T20325 7429-7434 UMLS/C0253050 denotes STAT3
T20324 8006-8012 UMLS/C1522410 denotes igher
T20323 7090-7094 UMLS/C1522410 denotes High
T20322 8203-8209 UMLS/C1873497 denotes ormal
T20321 7313-7323 UMLS/C0021467 denotes inhibition
T20320 7589-7596 UMLS/C0021469 denotes inhibit
T20319 7421-7428 UMLS/C0021469 denotes inhibit
T20318 7313-7323 UMLS/C0021469 denotes inhibition
T20317 7381-7384 UMLS/C2348947 denotes has
T20316 8252-8255 UMLS/C0349966 denotes ig.
T20315 8098-8101 UMLS/C0349966 denotes ig.
T20314 7252-7271 UMLS/C0678613 denotes feedback inhibition
T20313 7882-7888 UMLS/C1553875 denotes ctive
T20312 7282-7286 UMLS/C0032214 denotes play
T20311 8424-8431 UMLS/C0039194 denotes cells.
T20310 8215-8222 UMLS/C0039194 denotes cells
T20309 8157-8164 UMLS/C0039194 denotes cells
T20308 8089-8096 UMLS/C0039194 denotes cells
T20307 7988-7995 UMLS/C0039194 denotes cells
T20306 7869-7876 UMLS/C0039194 denotes cells
T20305 7803-7810 UMLS/C0039194 denotes cells,
T20304 7131-7138 UMLS/C0039194 denotes T cells
T20303 7295-7299 UMLS/C1705809 denotes role
T20302 7295-7299 UMLS/C1705812 denotes role
T20301 7503-7512 UMLS/C0443204 denotes divergent
T20300 7295-7299 UMLS/C1705810 denotes role
T20299 7295-7299 UMLS/C1705811 denotes role
T20298 8262-8272 UMLS/C0183683 denotes upporting
T20297 8039-8045 UMLS/C0456079 denotes evels
T20296 8013-8019 UMLS/C0456079 denotes evels
T20295 7816-7822 UMLS/C0456079 denotes evels
T20294 7932-7940 UMLS/C1707455 denotes ompared
T20293 8076-8083 UMLS/C1550141 denotes ontrol
T20292 7918-7926 UMLS/C1550141 denotes ontrols
T20291 8312-8317 UMLS/C1149215 denotes L-10-
T20290 7761-7766 UMLS/C1149215 denotes L-10-
T20289 7597-7602 UMLS/C1149215 denotes IL-10
T20288 7532-7537 UMLS/C1149215 denotes IL-10
T20287 7473-7478 UMLS/C1149215 denotes IL-10
T20286 7295-7299 UMLS/C0035820 denotes role
T20285 8039-8045 UMLS/C0441889 denotes evels
T20284 8013-8019 UMLS/C0441889 denotes evels
T20283 7816-7822 UMLS/C0441889 denotes evels
T20282 8383-8387 UMLS/C0449719 denotes art
T20281 7282-7286 UMLS/C0600138 denotes play
T20280 8246-8250 UMLS/C1149241 denotes L-6
T20279 7523-7527 UMLS/C1149241 denotes IL-6
T20278 7457-7461 UMLS/C1149241 denotes IL-6
T20277 7139-7143 UMLS/C1149241 denotes IL-6
T20276 7680-7685 UMLS/C1335872 denotes TAT1
T20275 8189-8199 UMLS/C0185117 denotes xpression
T20274 8121-8131 UMLS/C0185117 denotes xpression
T20273 7095-7105 UMLS/C0185117 denotes expression
T20272 8033-8038 UMLS/C1550472 denotes ower
T20271 8055-8066 UMLS/C1519595 denotes ranscripts
T20270 8262-8272 UMLS/C1317973 denotes upporting
T20269 7163-7173 UMLS/C1999216 denotes inhibitors
T20268 8332-8342 UMLS/C1879547 denotes ctivation
T20267 7781-7791 UMLS/C1879547 denotes ctivation
T20266 7686-7696 UMLS/C1879547 denotes ctivation
T20265 7618-7628 UMLS/C1879547 denotes activation
T20264 7435-7445 UMLS/C1879547 denotes activation
T20263 7571-7575 UMLS/C0085732 denotes able
T20262 8246-8250 UMLS/C1527132 denotes L-6
T20261 7523-7527 UMLS/C1527132 denotes IL-6
T20260 7457-7461 UMLS/C1527132 denotes IL-6
T20259 7139-7143 UMLS/C1527132 denotes IL-6
T20258 8383-8387 UMLS/C1552020 denotes art
T20257 7633-7641 UMLS/C0178539 denotes cellular
T20256 8383-8387 UMLS/C1148523 denotes art
T20255 8223-8233 UMLS/C1948023 denotes timulated
T20254 8312-8317 UMLS/C1522550 denotes L-10-
T20253 7761-7766 UMLS/C1522550 denotes L-10-
T20252 7597-7602 UMLS/C1522550 denotes IL-10
T20251 7532-7537 UMLS/C1522550 denotes IL-10
T20250 7473-7478 UMLS/C1522550 denotes IL-10
T20249 8312-8317 UMLS/C1334098 denotes L-10-
T20248 7761-7766 UMLS/C1334098 denotes L-10-
T20247 7597-7602 UMLS/C1334098 denotes IL-10
T20246 7532-7537 UMLS/C1334098 denotes IL-10
T20245 7473-7478 UMLS/C1334098 denotes IL-10
T20244 8076-8083 UMLS/C0009932 denotes ontrol
T20243 7918-7926 UMLS/C0009932 denotes ontrols
T20242 7842-7857 UMLS/C1515670 denotes RNA expression
T20241 8006-8012 UMLS/C1561957 denotes igher
T20240 7090-7094 UMLS/C1561957 denotes High
T20239 8006-8012 UMLS/C1561958 denotes igher
T20238 7090-7094 UMLS/C1561958 denotes High
T20237 8246-8250 UMLS/C0021760 denotes L-6
T20236 7523-7527 UMLS/C0021760 denotes IL-6
T20235 7457-7461 UMLS/C0021760 denotes IL-6
T20234 7139-7143 UMLS/C0021760 denotes IL-6
T20233 7892-7900 UMLS/C0030705 denotes atients
T20232 8246-8250 UMLS/C1334122 denotes L-6
T20231 7523-7527 UMLS/C1334122 denotes IL-6
T20230 7457-7461 UMLS/C1334122 denotes IL-6
T20229 7139-7143 UMLS/C1334122 denotes IL-6
T20228 7571-7575 UMLS/C1299581 denotes able
T20227 7735-7743 UMLS/C1314939 denotes nvolved
T20226 7892-7900 UMLS/C1578479 denotes atients
T20225 7177-7181 UMLS/C1150611 denotes JAKs
T20224 8189-8199 UMLS/C0017262 denotes xpression
T20223 8121-8131 UMLS/C0017262 denotes xpression
T20222 7095-7105 UMLS/C0017262 denotes expression
T20221 7892-7900 UMLS/C1578483 denotes atients
T20220 7892-7900 UMLS/C1578480 denotes atients
T20219 7892-7900 UMLS/C1578481 denotes atients
T20218 7892-7900 UMLS/C1578486 denotes atients
T20217 7706-7715 UMLS/C0521095 denotes etermine
T20216 7892-7900 UMLS/C1578484 denotes atients
T20215 7892-7900 UMLS/C1578485 denotes atients
T20214 7336-7341 UMLS/C1556044 denotes other
T20213 8277-8287 UMLS/C2700217 denotes unctional
T20212 7680-7685 UP/P42229 denotes TAT1
T20211 7882-7888 UMLS/C1561511 denotes ctive
T20210 7163-7173 UMLS/C0243077 denotes inhibitors
T20209 7882-7888 UMLS/C1561512 denotes ctive
T20208 7882-7888 UMLS/C1561513 denotes ctive
T20207 7199-7207 UMLS/C0033684 denotes proteins
T20206 8033-8038 UMLS/C0441994 denotes ower
T20205 7961-7974 UMLS/C1709846 denotes eal-time PCR.
T20204 7642-7651 UMLS/C1704632 denotes responses
T20203 7513-7519 UMLS/C0441472 denotes action
T20202 7336-7341 UMLS/C1955473 denotes other
T20201 7385-7393 UMLS/C0332185 denotes recently
T20200 7243-7251 UMLS/C1513916 denotes negative
T20199 7243-7251 UMLS/C0205160 denotes negative
T20198 7735-7743 UMLS/C1947935 denotes nvolved
T20197 7289-7294 UMLS/C0205164 denotes major
T20196 8033-8038 UMLS/C1708760 denotes ower
T20195 7218-7222 UMLS/C0205171 denotes only
T20194 7656-7660 UMLS/C0205170 denotes well
T20193 7882-7888 UMLS/C0205177 denotes ctive
T20192 8033-8038 UMLS/C1619811 denotes ower
T20191 7513-7519 UMLS/C1552007 denotes action
T20190 8103-8105 UMLS/C1553638 denotes a)
T20189 7882-7888 UMLS/C2347179 denotes ctive
T20188 8312-8317 UMLS/C0085295 denotes L-10-
T20187 7761-7766 UMLS/C0085295 denotes L-10-
T20186 7597-7602 UMLS/C0085295 denotes IL-10
T20185 7532-7537 UMLS/C0085295 denotes IL-10
T20184 7473-7478 UMLS/C0085295 denotes IL-10
T20183 8033-8038 UMLS/C1548802 denotes ower
T20182 8203-8209 UMLS/C1704701 denotes ormal
T20181 8029-8032 UMLS/C0005341 denotes ut
T20180 7462-7465 UMLS/C0005341 denotes but
T20179 7273-7276 UMLS/C0005341 denotes but
T20178 7724-7729 UMLS/C0299250 denotes OCSs
T20177 7670-7679 UMLS/C0127400 denotes mediated
T20176 7603-7611 UMLS/C0127400 denotes mediated
T20175 7230-7239 UMLS/C0127400 denotes mediators
T20174 8388-8390 UMLS/C0319022 denotes o
T20173 8361-8363 UMLS/C0319022 denotes o
T20172 7703-7705 UMLS/C0319022 denotes o
T20171 7576-7578 UMLS/C0319022 denotes to
T20170 7405-7407 UMLS/C0319022 denotes to
T20169 7670-7679 UMLS/C0086597 denotes mediated
T20168 7603-7611 UMLS/C0086597 denotes mediated
T20167 8394-8403 UMLS/C2346714 denotes bundance
T20166 8203-8209 UMLS/C1550457 denotes ormal
T20165 8141-8145 UMLS/C0035696 denotes RNA
T20164 7115-7119 UMLS/C0035696 denotes mRNA
T20163 7882-7888 UMLS/C1561510 denotes ctive
T20162 7882-7888 UMLS/C1561509 denotes ctive
T20161 7882-7888 UMLS/C1561508 denotes ctive
T20160 7882-7888 UMLS/C1561507 denotes ctive
T20391 7218-7222 UMLS/C1720467 denotes only
T20390 8076-8083 UMLS/C2587213 denotes ontrol
T20389 7918-7926 UMLS/C2587213 denotes ontrols
T20388 7230-7239 UMLS/C1363844 denotes mediators
T20387 8033-8038 UMLS/C1299352 denotes ower
T20386 8006-8012 UMLS/C1299351 denotes igher
T20385 7090-7094 UMLS/C1299351 denotes High
T20384 7488-7498 UMLS/C0851285 denotes regulating
T20383 7223-7226 UMLS/C1551336 denotes act
T20382 8240-8245 UMLS/C0439275 denotes g/ml
T20381 8203-8209 UMLS/C0205307 denotes ormal
T20380 7996-8005 UMLS/C0332256 denotes ontained
T20379 8049-8054 UMLS/C1426212 denotes OCS3
T20378 7836-7841 UMLS/C1426212 denotes OCS3
T20377 7375-7380 UMLS/C1426212 denotes SOCS3
T20376 7193-7198 UMLS/C1426212 denotes SOCS3
T20375 8288-8300 UMLS/C0237881 denotes ignificance.
T20374 7724-7729 UMLS/C1332762 denotes OCSs
T20373 8262-8272 UMLS/C0344211 denotes upporting
T20372 7361-7369 UMLS/C1705987 denotes pathways
T20371 7633-7641 UMLS/C0007634 denotes cellular
T20370 7466-7469 UMLS/C1518422 denotes not
T20369 7214-7217 UMLS/C1518422 denotes not
T20368 8407-8412 UMLS/C1426208 denotes OCS1
T20367 8135-8140 UMLS/C1426208 denotes OCS1
T20366 8023-8028 UMLS/C1426208 denotes OCS1
T20365 7826-7831 UMLS/C1426208 denotes OCS1
T20364 7562-7567 UMLS/C1426208 denotes SOCS1
T20363 7183-7188 UMLS/C1426208 denotes SOCS1
T20362 7109-7114 UMLS/C1426208 denotes SOCS1
T20361 8076-8083 UMLS/C0332298 denotes ontrol
T20360 7918-7926 UMLS/C0332298 denotes ontrols
T20359 7892-7900 UMLS/C1705908 denotes atients
T20358 7996-8005 UMLS/C2700400 denotes ontained
T20357 8318-8325 UMLS/C0205263 denotes nduced
T20356 7767-7774 UMLS/C0205263 denotes nduced
T20355 7446-7453 UMLS/C0205263 denotes induced
T20354 7144-7151 UMLS/C0205263 denotes induces
T20353 8033-8038 UMLS/C1611820 denotes ower
T20352 8006-8012 UMLS/C0205250 denotes igher
T20351 7090-7094 UMLS/C0205250 denotes High
T20350 8033-8038 UMLS/C0205251 denotes ower
T18007 5913-5917 UMLS/C0323983 denotes this
T18006 4807-4813 UMLS/C1704727 denotes family
T18005 6770-6780 UMLS/C1548180 denotes duction (F
T18004 6658-6668 UMLS/C1548180 denotes oduction w
T18003 6427-6437 UMLS/C1548180 denotes roduction
T18002 6566-6570 UMLS/C1332709 denotes D28
T18001 6927-6937 UMLS/C0205322 denotes sistent ex
T18000 5256-5266 UMLS/C0205322 denotes persistent
T17999 5750-5757 UMLS/C2587213 denotes control
T17998 6808-6812 UMLS/C1299351 denotes h co
T17997 6176-6182 UMLS/C1299351 denotes higher
T17996 5295-5299 UMLS/C1299351 denotes high
T17995 7027-7037 UMLS/C0237834 denotes istance to
T17994 5405-5415 UMLS/C0237834 denotes resistance
T17993 6380-6388 UMLS/C1260953 denotes suppress
T17992 6617-6622 UMLS/C0439275 denotes g/ml
T17991 6494-6499 UMLS/C0439275 denotes g/ml
T17990 5224-5229 UMLS/C0439275 denotes ng/ml
T17989 5758-5766 UMLS/C0003241 denotes antibody
T17988 5738-5746 UMLS/C0003241 denotes antibody
T17987 6519-6525 UMLS/C0205307 denotes ormal
T17986 5595-5601 UMLS/C0205307 denotes Normal
T17985 5512-5518 UMLS/C0205307 denotes normal
T17984 4714-4720 UMLS/C0205307 denotes normal
T17983 6120-6124 UMLS/C0332268 denotes lack
T17982 6961-6964 UMLS/C0337876 denotes ha
T17981 6316-6319 UMLS/C0337876 denotes may
T17980 6206-6209 UMLS/C0337876 denotes may
T17979 6455-6460 UMLS/C0231290 denotes fter
T17978 6636-6641 UMLS/C0439227 denotes ours,
T17977 6512-6517 UMLS/C0439227 denotes ours,
T17976 6075-6084 UMLS/C0332256 denotes contained
T17975 5666-5676 UMLS/C0332256 denotes containing
T17974 6008-6015 UMLS/C1546471 denotes results
T17973 4807-4813 UMLS/C1555907 denotes family
T17972 6950-6955 UMLS/C1151254 denotes um IL
T17971 6337-6342 UMLS/C1151254 denotes serum
T17970 6151-6156 UMLS/C1151254 denotes serum
T17969 6088-6092 UMLS/C1151254 denotes sera
T17968 5835-5840 UMLS/C1151254 denotes serum
T17967 5681-5686 UMLS/C1151254 denotes serum
T17966 5169-5173 UMLS/C1151254 denotes sera
T17965 5651-5665 UMLS/C0010454 denotes culture medium
T17964 6566-6570 UMLS/C1426202 denotes D28
T17963 6347-6351 UMLS/C0332282 denotes next
T17962 6713-6725 UMLS/C0007634 denotes rmal cells r
T17961 5898-5901 UMLS/C1518422 denotes not
T17960 5538-5541 UMLS/C1518422 denotes not
T17959 4834-4839 UMLS/C0537670 denotes IL-11
T17958 5642-5645 UMLS/C0439232 denotes min
T17957 5750-5757 UMLS/C0332298 denotes control
T17956 6106-6114 UMLS/C1705908 denotes patients
T17955 5702-5710 UMLS/C1705908 denotes patients
T17954 5187-5195 UMLS/C1705908 denotes patients
T17953 6075-6084 UMLS/C2700400 denotes contained
T17952 5666-5676 UMLS/C2700400 denotes containing
T17951 6989-6998 UMLS/C0205263 denotes uction of
T17950 5853-5859 UMLS/C0205263 denotes induce
T17949 5070-5077 UMLS/C0205263 denotes induces
T17948 4952-4963 UMLS/C0332287 denotes addition to
T17947 6808-6812 UMLS/C0205250 denotes h co
T17942 6306-6315 UMLS/C1710082 denotes signaling
T17941 6075-6084 UMLS/C1549781 denotes contained
T17940 5666-5676 UMLS/C1549781 denotes containing
T17939 5772-5776 UMLS/C1366753 denotes STAT
T17938 5959-5973 UMLS/C1446680 denotes neutralization
T17937 5208-5216 UMLS/C0442726 denotes detected
T17936 4807-4813 UMLS/C1552262 denotes family
T17935 6519-6525 UMLS/C2347086 denotes ormal
T17934 5595-5601 UMLS/C2347086 denotes Normal
T17933 5512-5518 UMLS/C2347086 denotes normal
T17932 4714-4720 UMLS/C2347086 denotes normal
T17931 6813-6827 UMLS/C0086045 denotes centrations of
T17930 6183-6197 UMLS/C0086045 denotes concentrations
T17929 5300-5314 UMLS/C0086045 denotes concentrations
T17928 5959-5973 UMLS/C1578828 denotes neutralization
T17927 5553-5562 UMLS/C0680240 denotes agreement
T17926 6323-6330 UMLS/C0449450 denotes present
T17925 6989-6998 UMLS/C1621983 denotes uction of
T17924 6749-6759 UMLS/C1628982 denotes hibition o
T17923 5425-5435 UMLS/C1628982 denotes inhibition
T17922 4988-4995 UMLS/C1705923 denotes studies
T17921 5374-5383 UMLS/C0443318 denotes sustained
T17920 6842-6850 UMLS/C1709059 denotes ulate T-
T17919 7002-7007 UMLS/C1367307 denotes T3 ac
T17918 6260-6265 UMLS/C1367307 denotes STAT3
T17917 6051-6056 UMLS/C1367307 denotes STAT3
T17916 5918-5923 UMLS/C1367307 denotes STAT3
T17915 5888-5893 UMLS/C1367307 denotes STAT3
T17914 5465-5470 UMLS/C1367307 denotes STAT3
T17913 5384-5389 UMLS/C1367307 denotes STAT3
T17912 5105-5110 UMLS/C1367307 denotes STAT3
T17911 4734-4739 UMLS/C1367307 denotes STAT3
T17910 4658-4663 UMLS/C1367307 denotes STAT3
T17909 5577-5589 UMLS/C0700325 denotes observations
T17908 6519-6525 UMLS/C0439166 denotes ormal
T17907 5595-5601 UMLS/C0439166 denotes Normal
T17906 5512-5518 UMLS/C0439166 denotes normal
T17905 4714-4720 UMLS/C0439166 denotes normal
T17904 4924-4947 UMLS/C1749410 denotes epidermal growth factor
T17903 5982-5990 UMLS/C0439167 denotes activity
T17902 5750-5757 UMLS/C0243148 denotes control
T17901 6213-6221 UMLS/C1514873 denotes required
T17900 5533-5537 UMLS/C1511726 denotes data
T17899 4841-4867 UP/P09056 denotes leukemia inhibitory factor
T17898 4841-4867 UP/P15018 denotes leukemia inhibitory factor
T17897 6836-6841 UMLS/C0344312 denotes ld mo
T17896 6374-6379 UMLS/C0344312 denotes could
T17895 4807-4813 UMLS/C2700055 denotes family
T17894 6300-6305 UP/P42224 denotes STAT1
T17893 6226-6231 UP/P42224 denotes STAT1
T17892 6128-6133 UP/P42224 denotes STAT1
T17891 5902-5907 UP/P42224 denotes STAT1
T17890 5455-5460 UP/P42224 denotes STAT1
T17889 5577-5589 UMLS/C0302523 denotes observations
T17888 5330-5347 UMLS/C0005775 denotes blood circulation
T17887 6950-6955 UMLS/C1550100 denotes um IL
T17886 6337-6342 UMLS/C1550100 denotes serum
T17885 6151-6156 UMLS/C1550100 denotes serum
T17884 6088-6092 UMLS/C1550100 denotes sera
T17883 5835-5840 UMLS/C1550100 denotes serum
T17882 5681-5686 UMLS/C1550100 denotes serum
T17881 5169-5173 UMLS/C1550100 denotes sera
T17880 5860-5884 UMLS/C1519726 denotes tyrosine phosphorylation
T17879 6306-6315 UMLS/C0037083 denotes signaling
T17878 6604-6611 UMLS/C1689985 denotes bsence
T17877 5959-5973 UMLS/C1550107 denotes neutralization
T17876 6836-6841 UMLS/C0006823 denotes ld mo
T17875 6374-6379 UMLS/C0006823 denotes could
T17874 6347-6351 UMLS/C1552851 denotes next
T17873 6842-6850 UMLS/C0443264 denotes ulate T-
T17872 6106-6114 UMLS/C1550655 denotes patients
T17871 5702-5710 UMLS/C1550655 denotes patients
T17870 5187-5195 UMLS/C1550655 denotes patients
T17869 5625-5634 UMLS/C1439852 denotes incubated
T17868 4775-4789 UP/Q776B5 denotes growth factors
T17867 6713-6725 UMLS/C1268443 denotes rmal cells r
T17866 4775-4789 UP/Q86607 denotes growth factors
T17865 6883-6888 UMLS/C1515187 denotes en to
T17864 5750-5757 UMLS/C1547100 denotes control
T17863 6972-6976 UMLS/C1704326 denotes e in
T17862 7002-7007 UMLS/C0253050 denotes T3 ac
T17861 6260-6265 UMLS/C0253050 denotes STAT3
T17860 6051-6056 UMLS/C0253050 denotes STAT3
T17859 5918-5923 UMLS/C0253050 denotes STAT3
T17858 5888-5893 UMLS/C0253050 denotes STAT3
T17857 5465-5470 UMLS/C0253050 denotes STAT3
T17856 5384-5389 UMLS/C0253050 denotes STAT3
T17855 5105-5110 UMLS/C0253050 denotes STAT3
T17854 4734-4739 UMLS/C0253050 denotes STAT3
T17853 4658-4663 UMLS/C0253050 denotes STAT3
T17852 4775-4789 UP/Q8V307 denotes growth factors
T17851 6808-6812 UMLS/C1522410 denotes h co
T17850 6176-6182 UMLS/C1522410 denotes higher
T17849 5295-5299 UMLS/C1522410 denotes high
T17848 4841-4867 UP/P17777 denotes leukemia inhibitory factor
T17847 6636-6641 UMLS/C0564385 denotes ours,
T17846 6512-6517 UMLS/C0564385 denotes ours,
T17845 4841-4867 UMLS/C1761537 denotes leukemia inhibitory factor
T17844 5050-5064 UMLS/C0039097 denotes synovial fluid
T17843 6673-6681 UMLS/C0079809 denotes asured b
T17842 6519-6525 UMLS/C1873497 denotes ormal
T17841 5595-5601 UMLS/C1873497 denotes Normal
T17840 5512-5518 UMLS/C1873497 denotes normal
T17839 4714-4720 UMLS/C1873497 denotes normal
T17838 6927-6937 UMLS/C0546816 denotes sistent ex
T17837 5256-5266 UMLS/C0546816 denotes persistent
T17836 5982-5990 UMLS/C0441655 denotes activity
T17835 6749-6759 UMLS/C0021467 denotes hibition o
T17834 5425-5435 UMLS/C0021467 denotes inhibition
T17833 7045-7055 UMLS/C0021469 denotes ibitory ef
T17832 6749-6759 UMLS/C0021469 denotes hibition o
T17831 6412-6419 UMLS/C0021469 denotes inhibit
T17830 5425-5435 UMLS/C0021469 denotes inhibition
T17829 4888-4918 UMLS/C1761525 denotes platelet-derived growth factor
T17828 6592-6600 UMLS/C0150312 denotes resence
T17827 6323-6330 UMLS/C0150312 denotes present
T17826 6171-6175 UMLS/C0439064 denotes much
T17825 4756-4760 UMLS/C0439064 denotes many
T17824 6558-6561 UMLS/C2698592 denotes D3
T17823 5758-5766 UMLS/C1621287 denotes antibody
T17822 5738-5746 UMLS/C1621287 denotes antibody
T17821 6782-6785 UMLS/C0349966 denotes . 5
T17820 5992-5995 UMLS/C0349966 denotes Fig
T17819 6096-6102 UMLS/C1553875 denotes active
T17818 5692-5698 UMLS/C1553875 denotes active
T17817 5439-5445 UMLS/C1553875 denotes active
T17816 5177-5183 UMLS/C1553875 denotes active
T17815 6347-6351 UMLS/C1883708 denotes next
T17814 6697-6709 UMLS/C1550147 denotes etreatment o
T17813 4988-4995 UMLS/C0557651 denotes studies
T17812 6851-6857 UMLS/C0039194 denotes ell re
T17811 6531-6538 UMLS/C0039194 denotes cells
T17810 6446-6453 UMLS/C0039194 denotes cells.
T17809 5607-5614 UMLS/C0039194 denotes T cells
T17808 5524-5531 UMLS/C0039194 denotes T cells
T17807 5284-5291 UMLS/C0039194 denotes T cells
T17806 4726-4733 UMLS/C0039194 denotes T cells
T17805 4873-4885 UMLS/C1335093 denotes oncostatin M
T17804 6972-6976 UMLS/C1705809 denotes e in
T17803 4873-4885 UMLS/C0069535 denotes oncostatin M
T17802 6972-6976 UMLS/C1705812 denotes e in
T17801 6972-6976 UMLS/C1705810 denotes e in
T17800 6972-6976 UMLS/C1705811 denotes e in
T17799 4775-4789 UP/P08441 denotes growth factors
T17798 6883-6888 UMLS/C1883727 denotes en to
T17797 6566-6570 UMLS/C0075747 denotes D28
T17796 4664-4694 UMLS/C1519062 denotes phosphorylation and inhibition
T17795 6246-6254 UMLS/C1707455 denotes compared
T17794 4888-4918 UMLS/C0032200 denotes platelet-derived growth factor
T17793 5750-5757 UMLS/C1550141 denotes control
T17792 6950-6955 UMLS/C0229671 denotes um IL
T17791 6337-6342 UMLS/C0229671 denotes serum
T17790 6151-6156 UMLS/C0229671 denotes serum
T17789 6088-6092 UMLS/C0229671 denotes sera
T17788 5835-5840 UMLS/C0229671 denotes serum
T17787 5681-5686 UMLS/C0229671 denotes serum
T17786 5169-5173 UMLS/C0229671 denotes sera
T17785 6813-6827 UMLS/C1446561 denotes centrations of
T17784 6183-6197 UMLS/C1446561 denotes concentrations
T17783 5300-5314 UMLS/C1446561 denotes concentrations
T17782 5772-5776 UMLS/C1548425 denotes STAT
T17781 4834-4839 UMLS/C1149216 denotes IL-11
T17780 7066-7071 UMLS/C1149215 denotes 10 in
T17779 6876-6881 UMLS/C1149215 denotes 10. T
T17778 6734-6739 UMLS/C1149215 denotes -10-m
T17777 6623-6628 UMLS/C1149215 denotes L-10
T17776 6403-6408 UMLS/C1149215 denotes IL-10
T17775 5419-5424 UMLS/C1149215 denotes IL-10
T17774 4964-4969 UMLS/C1149215 denotes IL-10
T17773 4698-4703 UMLS/C1149215 denotes IL-10
T17772 6950-6955 UMLS/C1546774 denotes um IL
T17771 6337-6342 UMLS/C1546774 denotes serum
T17770 6151-6156 UMLS/C1546774 denotes serum
T17769 6088-6092 UMLS/C1546774 denotes sera
T17768 5835-5840 UMLS/C1546774 denotes serum
T17767 5681-5686 UMLS/C1546774 denotes serum
T17766 5169-5173 UMLS/C1546774 denotes sera
T17765 6972-6976 UMLS/C0035820 denotes e in
T17764 6673-6681 UMLS/C1879489 denotes asured b
T17763 7027-7037 UMLS/C1522618 denotes istance to
T17762 5405-5415 UMLS/C1522618 denotes resistance
T17761 5577-5589 UMLS/C1554188 denotes observations
T17760 5642-5645 UMLS/C1552937 denotes min
T17759 6905-6913 UMLS/C2607943 denotes dings su
T17758 6956-6960 UMLS/C1149241 denotes 6 ma
T17757 6831-6835 UMLS/C1149241 denotes 6 co
T17756 6692-6696 UMLS/C1149241 denotes -6 p
T17755 6500-6504 UMLS/C1149241 denotes L-6
T17754 6369-6373 UMLS/C1149241 denotes IL-6
T17753 6201-6205 UMLS/C1149241 denotes IL-6
T17752 6030-6034 UMLS/C1149241 denotes IL-6
T17751 5977-5981 UMLS/C1149241 denotes IL-6
T17750 5504-5508 UMLS/C1149241 denotes IL-6
T17749 5318-5322 UMLS/C1149241 denotes IL-6
T17748 5144-5148 UMLS/C1149241 denotes IL-6
T17747 5019-5023 UMLS/C1149241 denotes IL-6
T17746 4828-4832 UMLS/C1149241 denotes IL-6
T17745 4802-4806 UMLS/C1149241 denotes IL-6
T17744 4644-4648 UMLS/C1149241 denotes IL-6
T17743 6300-6305 UMLS/C1335872 denotes STAT1
T17742 6226-6231 UMLS/C1335872 denotes STAT1
T17741 6128-6133 UMLS/C1335872 denotes STAT1
T17740 5902-5907 UMLS/C1335872 denotes STAT1
T17739 5455-5460 UMLS/C1335872 denotes STAT1
T17738 6961-6964 UMLS/C0454788 denotes ha
T17737 6316-6319 UMLS/C0454788 denotes may
T17736 6206-6209 UMLS/C0454788 denotes may
T17735 7056-7062 UMLS/C2348382 denotes ect of
T17734 6393-6399 UMLS/C2348382 denotes effect
T17733 4704-4710 UMLS/C2348382 denotes effect
T17732 6286-6296 UMLS/C1999216 denotes inhibitors
T17731 5208-5216 UMLS/C1511790 denotes detected
T17730 7008-7018 UMLS/C1879547 denotes ivation an
T17729 6266-6276 UMLS/C1879547 denotes activation
T17728 6232-6242 UMLS/C1879547 denotes activation
T17727 6134-6144 UMLS/C1879547 denotes activation
T17664 6176-6182 UMLS/C1561957 denotes higher
T17663 5295-5299 UMLS/C1561957 denotes high
T17662 6808-6812 UMLS/C1561958 denotes h co
T17661 6176-6182 UMLS/C1561958 denotes higher
T17660 5295-5299 UMLS/C1561958 denotes high
T17659 6956-6960 UMLS/C0021760 denotes 6 ma
T17658 6831-6835 UMLS/C0021760 denotes 6 co
T17657 6692-6696 UMLS/C0021760 denotes -6 p
T17656 6500-6504 UMLS/C0021760 denotes L-6
T17655 6369-6373 UMLS/C0021760 denotes IL-6
T17654 6201-6205 UMLS/C0021760 denotes IL-6
T17653 6030-6034 UMLS/C0021760 denotes IL-6
T17652 5977-5981 UMLS/C0021760 denotes IL-6
T17651 5504-5508 UMLS/C0021760 denotes IL-6
T17650 5318-5322 UMLS/C0021760 denotes IL-6
T17649 5144-5148 UMLS/C0021760 denotes IL-6
T17648 5019-5023 UMLS/C0021760 denotes IL-6
T17647 4828-4832 UMLS/C0021760 denotes IL-6
T17646 4802-4806 UMLS/C0021760 denotes IL-6
T17645 4644-4648 UMLS/C0021760 denotes IL-6
T17644 5809-5830 UMLS/C0949466 denotes western blot analysis
T17643 6042-6050 UMLS/C1527180 denotes dominant
T17642 6106-6114 UMLS/C0030705 denotes patients
T17641 5702-5710 UMLS/C0030705 denotes patients
T17640 5187-5195 UMLS/C0030705 denotes patients
T17639 6592-6600 UMLS/C0392148 denotes resence
T17638 6956-6960 UMLS/C1334122 denotes 6 ma
T17637 6831-6835 UMLS/C1334122 denotes 6 co
T17636 6692-6696 UMLS/C1334122 denotes -6 p
T17635 6500-6504 UMLS/C1334122 denotes L-6
T17634 6369-6373 UMLS/C1334122 denotes IL-6
T17633 6201-6205 UMLS/C1334122 denotes IL-6
T17632 6030-6034 UMLS/C1334122 denotes IL-6
T17631 5977-5981 UMLS/C1334122 denotes IL-6
T17630 5504-5508 UMLS/C1334122 denotes IL-6
T17629 5318-5322 UMLS/C1334122 denotes IL-6
T17628 5144-5148 UMLS/C1334122 denotes IL-6
T17627 5019-5023 UMLS/C1334122 denotes IL-6
T17626 4828-4832 UMLS/C1334122 denotes IL-6
T17625 4802-4806 UMLS/C1334122 denotes IL-6
T17624 4644-4648 UMLS/C1334122 denotes IL-6
T17623 5772-5776 UMLS/C1335960 denotes STAT
T17622 6213-6221 UMLS/C1556066 denotes required
T17621 5845-5849 UMLS/C1299581 denotes able
T17620 6106-6114 UMLS/C1578479 denotes patients
T17619 5702-5710 UMLS/C1578479 denotes patients
T17618 5187-5195 UMLS/C1578479 denotes patients
T17617 5772-5776 UMLS/C1420304 denotes STAT
T17616 5982-5990 UMLS/C1561536 denotes activity
T17615 6106-6114 UMLS/C1578483 denotes patients
T17614 5702-5710 UMLS/C1578483 denotes patients
T17613 5187-5195 UMLS/C1578483 denotes patients
T17612 6106-6114 UMLS/C1578480 denotes patients
T17611 5702-5710 UMLS/C1578480 denotes patients
T17610 5187-5195 UMLS/C1578480 denotes patients
T17609 6106-6114 UMLS/C1578481 denotes patients
T17608 5702-5710 UMLS/C1578481 denotes patients
T17607 5187-5195 UMLS/C1578481 denotes patients
T17606 6106-6114 UMLS/C1578486 denotes patients
T17605 5702-5710 UMLS/C1578486 denotes patients
T17604 5187-5195 UMLS/C1578486 denotes patients
T17603 6558-6561 UMLS/C0108779 denotes D3
T17602 6106-6114 UMLS/C1578484 denotes patients
T17601 5702-5710 UMLS/C1578484 denotes patients
T17600 5187-5195 UMLS/C1578484 denotes patients
T17599 6106-6114 UMLS/C1578485 denotes patients
T17598 5702-5710 UMLS/C1578485 denotes patients
T17597 5187-5195 UMLS/C1578485 denotes patients
T17596 5758-5766 UMLS/C0021027 denotes antibody
T17595 5738-5746 UMLS/C0021027 denotes antibody
T17594 4775-4789 UP/Q6RZT5 denotes growth factors
T17593 6604-6611 UMLS/C0332197 denotes bsence
T17592 6300-6305 UP/P42229 denotes STAT1
T17591 6226-6231 UP/P42229 denotes STAT1
T17590 6128-6133 UP/P42229 denotes STAT1
T17589 5902-5907 UP/P42229 denotes STAT1
T17588 5455-5460 UP/P42229 denotes STAT1
T17587 4834-4839 UMLS/C0083031 denotes IL-11
T17586 6096-6102 UMLS/C1561511 denotes active
T17585 5692-5698 UMLS/C1561511 denotes active
T17584 5439-5445 UMLS/C1561511 denotes active
T17583 5177-5183 UMLS/C1561511 denotes active
T17582 6286-6296 UMLS/C0243077 denotes inhibitors
T17581 6096-6102 UMLS/C1561512 denotes active
T17580 5692-5698 UMLS/C1561512 denotes active
T17579 5439-5445 UMLS/C1561512 denotes active
T17578 5177-5183 UMLS/C1561512 denotes active
T17577 6096-6102 UMLS/C1561513 denotes active
T17576 5692-5698 UMLS/C1561513 denotes active
T17575 5439-5445 UMLS/C1561513 denotes active
T17574 5177-5183 UMLS/C1561513 denotes active
T17573 6792-6802 UMLS/C1444656 denotes icating th
T17572 6016-6024 UMLS/C1444656 denotes indicate
T17571 4775-4789 UP/P20494 denotes growth factors
T17570 5267-5275 UMLS/C1704625 denotes exposure
T17569 5197-5207 UMLS/C0332183 denotes frequently
T17568 5568-5576 UMLS/C0205156 denotes previous
T17567 4979-4987 UMLS/C0205156 denotes previous
T17566 4841-4867 UMLS/C0125606 denotes leukemia inhibitory factor
T17565 6604-6611 UMLS/C0424530 denotes bsence
T17564 5031-5036 UMLS/C0205164 denotes major
T17563 4841-4867 UP/Q27956 denotes leukemia inhibitory factor
T17562 6213-6221 UMLS/C1546857 denotes required
T17561 5577-5589 UMLS/C1548358 denotes observations
T17560 6938-6949 UMLS/C0332157 denotes osure to se
T17559 5267-5275 UMLS/C0332157 denotes exposure
T17558 5267-5275 UMLS/C0274281 denotes exposure
T17557 4988-4995 UMLS/C1880229 denotes studies
T17556 5114-5131 UMLS/C0806987 denotes mononuclear cells
T17555 6096-6102 UMLS/C0205177 denotes active
T17554 5692-5698 UMLS/C0205177 denotes active
T17553 5439-5445 UMLS/C0205177 denotes active
T17552 5177-5183 UMLS/C0205177 denotes active
T17551 4841-4867 UP/O62728 denotes leukemia inhibitory factor
T17550 5577-5589 UMLS/C0557985 denotes observations
T17549 7027-7037 UMLS/C0683598 denotes istance to
T17548 5405-5415 UMLS/C0683598 denotes resistance
T17547 6096-6102 UMLS/C2347179 denotes active
T17546 5692-5698 UMLS/C2347179 denotes active
T17545 5439-5445 UMLS/C2347179 denotes active
T17544 5177-5183 UMLS/C2347179 denotes active
T17543 5997-5999 UMLS/C1553637 denotes 5a
T17542 7066-7071 UMLS/C0085295 denotes 10 in
T17541 6876-6881 UMLS/C0085295 denotes 10. T
T17540 6734-6739 UMLS/C0085295 denotes -10-m
T17539 6623-6628 UMLS/C0085295 denotes L-10
T17538 6403-6408 UMLS/C0085295 denotes IL-10
T17537 5419-5424 UMLS/C0085295 denotes IL-10
T17536 4964-4969 UMLS/C0085295 denotes IL-10
T17535 4698-4703 UMLS/C0085295 denotes IL-10
T17534 5577-5589 UMLS/C1964257 denotes observations
T17533 6726-6733 UMLS/C0392756 denotes duced I
T17532 6914-6921 UMLS/C1705535 denotes gest th
T17531 6157-6165 UMLS/C1705535 denotes suggests
T17530 4775-4789 UP/O57166 denotes growth factors
T17529 6519-6525 UMLS/C1704701 denotes ormal
T17528 5595-5601 UMLS/C1704701 denotes Normal
T17527 5512-5518 UMLS/C1704701 denotes normal
T17526 4714-4720 UMLS/C1704701 denotes normal
T17525 4775-4789 UMLS/C0018284 denotes growth factors
T17524 5894-5897 UMLS/C0005341 denotes but
T17523 4975-4978 UMLS/C0005341 denotes but
T17522 7038-7040 UMLS/C0319022 denotes th
T17521 6873-6875 UMLS/C0319022 denotes IL
T17520 6409-6411 UMLS/C0319022 denotes to
T17519 5850-5852 UMLS/C0319022 denotes to
T17518 5416-5418 UMLS/C0319022 denotes to
T17517 5292-5294 UMLS/C0319022 denotes to
T17516 6740-6748 UMLS/C0127400 denotes diated i
T17515 4649-4657 UMLS/C0127400 denotes mediated
T17514 6740-6748 UMLS/C0086597 denotes diated i
T17513 4649-4657 UMLS/C0086597 denotes mediated
T17512 6673-6681 UMLS/C0444706 denotes asured b
T17511 6352-6360 UMLS/C0332128 denotes examined
T17510 5797-5805 UMLS/C0332128 denotes examined
T17509 5239-5247 UMLS/C0332128 denotes examined
T17508 5157-5165 UMLS/C2346714 denotes abundant
T17507 4924-4947 UMLS/C0242275 denotes epidermal growth factor
T17506 4905-4933 UMLS/C0242275 denotes growth factor, and epidermal
T17505 6519-6525 UMLS/C1550457 denotes ormal
T17504 5595-5601 UMLS/C1550457 denotes Normal
T17503 5512-5518 UMLS/C1550457 denotes normal
T17502 4714-4720 UMLS/C1550457 denotes normal
T17501 4775-4789 UP/P08072 denotes growth factors
T17500 5577-5589 UMLS/C0941132 denotes observations
T17499 6213-6221 UMLS/C1619636 denotes required
T17498 6096-6102 UMLS/C1561510 denotes active
T17497 5692-5698 UMLS/C1561510 denotes active
T17496 5439-5445 UMLS/C1561510 denotes active
T17495 5177-5183 UMLS/C1561510 denotes active
T17494 4775-4789 UP/P33804 denotes growth factors
T17493 6096-6102 UMLS/C1561509 denotes active
T17492 5692-5698 UMLS/C1561509 denotes active
T17491 5439-5445 UMLS/C1561509 denotes active
T17490 5177-5183 UMLS/C1561509 denotes active
T17489 6096-6102 UMLS/C1561508 denotes active
T17488 5692-5698 UMLS/C1561508 denotes active
T17487 5439-5445 UMLS/C1561508 denotes active
T17486 5177-5183 UMLS/C1561508 denotes active
T17485 6096-6102 UMLS/C1561507 denotes active
T17484 5692-5698 UMLS/C1561507 denotes active
T17483 5439-5445 UMLS/C1561507 denotes active
T17482 5177-5183 UMLS/C1561507 denotes active
T17481 4988-4995 UMLS/C0947630 denotes studies
T17946 6176-6182 UMLS/C0205250 denotes higher
T17945 5295-5299 UMLS/C0205250 denotes high
T17944 6008-6015 UMLS/C0332294 denotes results
T17943 6008-6015 UMLS/C1274040 denotes results
T17480 5777-5792 UMLS/C0031715 denotes phosphorylation
T17479 5471-5486 UMLS/C0031715 denotes phosphorylation
T17478 4807-4813 UMLS/C1563343 denotes family
T17477 6519-6525 UMLS/C1551394 denotes ormal
T17476 5595-5601 UMLS/C1551394 denotes Normal
T17475 5512-5518 UMLS/C1551394 denotes normal
T17474 4714-4720 UMLS/C1551394 denotes normal
T17473 6096-6102 UMLS/C1547419 denotes active
T17472 5692-5698 UMLS/C1547419 denotes active
T17471 5439-5445 UMLS/C1547419 denotes active
T17470 5177-5183 UMLS/C1547419 denotes active
T17469 4817-4826 UMLS/C0079189 denotes cytokines
T17468 4761-4770 UMLS/C0079189 denotes cytokines
T17467 4775-4789 UP/Q9JFH4 denotes growth factors
T17466 5750-5757 UMLS/C1882979 denotes control
T17465 5568-5576 UMLS/C1552607 denotes previous
T17464 4979-4987 UMLS/C1552607 denotes previous
T17726 6057-6067 UMLS/C1879547 denotes activating
T17725 5924-5934 UMLS/C1879547 denotes activation
T17724 5491-5500 UMLS/C1879547 denotes activated
T17723 5390-5400 UMLS/C1879547 denotes activation
T17722 5091-5101 UMLS/C1879547 denotes activation
T17721 4743-4752 UMLS/C1879547 denotes activated
T17720 6008-6015 UMLS/C1280519 denotes results
T17719 4807-4813 UMLS/C0015576 denotes family
T17718 4988-4995 UMLS/C0008972 denotes studies
T17717 5845-5849 UMLS/C0085732 denotes able
T17716 4988-4995 UMLS/C0008976 denotes studies
T17715 6956-6960 UMLS/C1527132 denotes 6 ma
T17714 6831-6835 UMLS/C1527132 denotes 6 co
T17713 6692-6696 UMLS/C1527132 denotes -6 p
T17712 6500-6504 UMLS/C1527132 denotes L-6
T17711 6369-6373 UMLS/C1527132 denotes IL-6
T17710 6201-6205 UMLS/C1527132 denotes IL-6
T17709 6030-6034 UMLS/C1527132 denotes IL-6
T17708 5977-5981 UMLS/C1527132 denotes IL-6
T17707 5504-5508 UMLS/C1527132 denotes IL-6
T17706 5318-5322 UMLS/C1527132 denotes IL-6
T17705 5144-5148 UMLS/C1527132 denotes IL-6
T17704 5019-5023 UMLS/C1527132 denotes IL-6
T17703 4828-4832 UMLS/C1527132 denotes IL-6
T17702 4802-4806 UMLS/C1527132 denotes IL-6
T17701 4644-4648 UMLS/C1527132 denotes IL-6
T17700 7056-7062 UMLS/C1280500 denotes ect of
T17699 6393-6399 UMLS/C1280500 denotes effect
T17698 4704-4710 UMLS/C1280500 denotes effect
T17697 4834-4839 UMLS/C1334100 denotes IL-11
T17696 5642-5645 UMLS/C0702093 denotes min
T17695 6673-6681 UMLS/C0242485 denotes asured b
T17694 5772-5776 UMLS/C0205548 denotes STAT
T17693 5352-5363 UMLS/C1273518 denotes responsible
T17692 7066-7071 UMLS/C1522550 denotes 10 in
T17691 6876-6881 UMLS/C1522550 denotes 10. T
T17690 6734-6739 UMLS/C1522550 denotes -10-m
T17689 6623-6628 UMLS/C1522550 denotes L-10
T17688 6403-6408 UMLS/C1522550 denotes IL-10
T17687 5419-5424 UMLS/C1522550 denotes IL-10
T17686 4964-4969 UMLS/C1522550 denotes IL-10
T17685 4698-4703 UMLS/C1522550 denotes IL-10
T17684 6455-6460 UMLS/C0687676 denotes fter
T17683 6544-6554 UMLS/C1948023 denotes timulated
T17682 7066-7071 UMLS/C1334098 denotes 10 in
T17681 6876-6881 UMLS/C1334098 denotes 10. T
T17680 6734-6739 UMLS/C1334098 denotes -10-m
T17679 6623-6628 UMLS/C1334098 denotes L-10
T17678 6403-6408 UMLS/C1334098 denotes IL-10
T17677 5419-5424 UMLS/C1334098 denotes IL-10
T17676 4964-4969 UMLS/C1334098 denotes IL-10
T17675 4698-4703 UMLS/C1334098 denotes IL-10
T17674 4775-4789 UP/P01136 denotes growth factors
T17673 6889-6897 UMLS/C1883357 denotes ether, t
T17672 4988-4995 UMLS/C2603343 denotes studies
T17671 5750-5757 UMLS/C0009932 denotes control
T17670 5267-5275 UMLS/C0728853 denotes exposure
T17669 4817-4826 UMLS/C1524094 denotes cytokines
T17668 4761-4770 UMLS/C1524094 denotes cytokines
T17667 4988-4995 UMLS/C2349977 denotes studies
T17666 6685-6690 UMLS/C0014441 denotes ISA.
T17665 6808-6812 UMLS/C1561957 denotes h co
T15851 4028-4032 UMLS/C0323983 denotes this
T15850 4501-4505 UMLS/C1548425 denotes STAT
T15849 4125-4129 UMLS/C1720467 denotes only
T15848 4527-4532 UMLS/C1149215 denotes IL-10
T15847 4485-4490 UMLS/C1149215 denotes IL-10
T15846 4325-4330 UMLS/C1149215 denotes IL-10
T15845 4226-4231 UMLS/C1149215 denotes IL-10
T15844 4168-4173 UMLS/C1149215 denotes IL-10
T15843 3870-3875 UMLS/C1149215 denotes IL-10
T15842 3701-3706 UMLS/C1149215 denotes IL-10
T15841 3487-3492 UMLS/C1149215 denotes IL-10
T15840 3286-3291 UMLS/C1149215 denotes IL-10
T15839 3199-3204 UMLS/C1149215 denotes IL-10
T15838 3767-3775 UMLS/C2587213 denotes controls
T15837 3479-3483 UMLS/C0035820 denotes role
T15836 3559-3568 UMLS/C1446409 denotes confirmed
T15835 3259-3270 UMLS/C1546938 denotes interaction
T15834 3894-3897 UMLS/C1552937 denotes min
T15833 4162-4167 UMLS/C0439275 denotes ng/ml
T15832 4407-4413 UMLS/C0205307 denotes normal
T15831 3901-3907 UMLS/C0205307 denotes normal
T15830 3462-3467 UMLS/C0600138 denotes plays
T15829 4339-4344 UMLS/C1335872 denotes STAT1
T15828 3666-3671 UMLS/C1335872 denotes STAT1
T15827 3376-3381 UMLS/C1335872 denotes STAT1
T15826 4558-4561 UMLS/C0454788 denotes may
T15825 3864-3869 UMLS/C0231290 denotes after
T15824 4558-4561 UMLS/C0337876 denotes may
T15718 4015-4023 UMLS/C1578479 denotes patients
T15717 3741-3749 UMLS/C1578479 denotes patients
T15716 4501-4505 UMLS/C1420304 denotes STAT
T15715 3259-3270 UMLS/C0687133 denotes interaction
T15714 4267-4272 UMLS/C0037088 denotes found
T15713 4015-4023 UMLS/C1578483 denotes patients
T15712 3741-3749 UMLS/C1578483 denotes patients
T15711 4015-4023 UMLS/C1578480 denotes patients
T15710 3741-3749 UMLS/C1578480 denotes patients
T15709 4015-4023 UMLS/C1578481 denotes patients
T15708 3741-3749 UMLS/C1578481 denotes patients
T15707 4015-4023 UMLS/C1578486 denotes patients
T15706 3741-3749 UMLS/C1578486 denotes patients
T15705 4015-4023 UMLS/C1578484 denotes patients
T15704 3741-3749 UMLS/C1578484 denotes patients
T15703 4339-4344 UP/P42224 denotes STAT1
T15702 3666-3671 UP/P42224 denotes STAT1
T15701 3376-3381 UP/P42224 denotes STAT1
T15700 4015-4023 UMLS/C1578485 denotes patients
T15699 3741-3749 UMLS/C1578485 denotes patients
T15698 3559-3568 UMLS/C0521093 denotes confirmed
T15697 4313-4318 UMLS/C1556044 denotes other
T15696 3300-3324 UMLS/C1519726 denotes tyrosine phosphorylation
T15695 3354-3375 UMLS/C0040648 denotes transcription factors
T15694 4339-4344 UP/P42229 denotes STAT1
T15693 3666-3671 UP/P42229 denotes STAT1
T15692 3376-3381 UP/P42229 denotes STAT1
T15691 4579-4585 UMLS/C1561511 denotes active
T15690 3731-3737 UMLS/C1561511 denotes active
T15689 4579-4585 UMLS/C1561512 denotes active
T15688 3731-3737 UMLS/C1561512 denotes active
T15687 4579-4585 UMLS/C1561513 denotes active
T15686 3731-3737 UMLS/C1561513 denotes active
T15685 4452-4460 UMLS/C1444656 denotes indicate
T15684 4593-4604 UMLS/C0596306 denotes association
T15683 3984-3992 UMLS/C0370215 denotes isolated
T15682 3559-3568 UMLS/C1456348 denotes confirmed
T15681 3545-3553 UMLS/C0332185 denotes recently
T15680 4313-4318 UMLS/C1955473 denotes other
T15679 4365-4377 UMLS/C0442737 denotes not detected
T15678 4319-4323 UMLS/C1552290 denotes hand
T15677 4479-4484 UMLS/C0205164 denotes major
T15676 4015-4023 UMLS/C1550655 denotes patients
T15675 3741-3749 UMLS/C1550655 denotes patients
T15674 3578-3589 UMLS/C1550652 denotes macrophages
T15673 3397-3407 UMLS/C1550652 denotes Macrophage
T15672 4125-4129 UMLS/C0205171 denotes only
T15671 4593-4604 UMLS/C0439849 denotes association
T15670 3593-3600 UMLS/C1880229 denotes studies
T15669 4579-4585 UMLS/C0205177 denotes active
T15668 3731-3737 UMLS/C0205177 denotes active
T15667 3767-3775 UMLS/C1547100 denotes controls
T15666 3479-3483 UMLS/C1704326 denotes role
T15665 4620-4625 UMLS/C0253050 denotes STAT3
T15664 4541-4546 UMLS/C0253050 denotes STAT3
T15663 4466-4471 UMLS/C0253050 denotes STAT3
T15662 4240-4245 UMLS/C0253050 denotes STAT3
T15661 4190-4195 UMLS/C0253050 denotes STAT3
T15660 4089-4094 UMLS/C0253050 denotes STAT3
T15659 4033-4038 UMLS/C0253050 denotes STAT3
T15658 3948-3953 UMLS/C0253050 denotes STAT3
T15657 3813-3818 UMLS/C0253050 denotes STAT3
T15656 3676-3681 UMLS/C0253050 denotes STAT3
T15655 3622-3627 UMLS/C0253050 denotes STAT3
T15654 3456-3461 UMLS/C0253050 denotes STAT3
T15653 3386-3391 UMLS/C0253050 denotes STAT3
T15652 3214-3219 UMLS/C0253050 denotes STAT3
T15651 4319-4323 UMLS/C1552301 denotes hand
T15650 4433-4435 UMLS/C1553636 denotes 4a
T15649 3927-3929 UMLS/C1553636 denotes 4a
T15648 4579-4585 UMLS/C2347179 denotes active
T15647 3731-3737 UMLS/C2347179 denotes active
T15646 4527-4532 UMLS/C0085295 denotes IL-10
T15645 4485-4490 UMLS/C0085295 denotes IL-10
T15644 4325-4330 UMLS/C0085295 denotes IL-10
T15643 4226-4231 UMLS/C0085295 denotes IL-10
T15642 4168-4173 UMLS/C0085295 denotes IL-10
T15641 3870-3875 UMLS/C0085295 denotes IL-10
T15640 3701-3706 UMLS/C0085295 denotes IL-10
T15639 3487-3492 UMLS/C0085295 denotes IL-10
T15638 3286-3291 UMLS/C0085295 denotes IL-10
T15637 3199-3204 UMLS/C0085295 denotes IL-10
T15636 4407-4413 UMLS/C1873497 denotes normal
T15635 3901-3907 UMLS/C1873497 denotes normal
T15634 3984-3992 UMLS/C0205409 denotes isolated
T15633 4407-4413 UMLS/C1704701 denotes normal
T15632 3901-3907 UMLS/C1704701 denotes normal
T15631 4151-4155 UMLS/C0439064 denotes much
T15630 3493-3501 UMLS/C0127400 denotes mediated
T15629 3205-3213 UMLS/C0127400 denotes mediated
T15628 3493-3501 UMLS/C0086597 denotes mediated
T15627 3205-3213 UMLS/C0086597 denotes mediated
T15626 3780-3788 UMLS/C0332128 denotes examined
T15625 4407-4413 UMLS/C1550457 denotes normal
T15624 3901-3907 UMLS/C1550457 denotes normal
T15623 3541-3544 UMLS/C2348947 denotes has
T15622 4428-4431 UMLS/C0349966 denotes Fig
T15621 4296-4299 UMLS/C0349966 denotes Fig
T15620 3922-3925 UMLS/C0349966 denotes Fig
T15619 4579-4585 UMLS/C1553875 denotes active
T15618 3731-3737 UMLS/C1553875 denotes active
T15617 4579-4585 UMLS/C1561510 denotes active
T15616 3731-3737 UMLS/C1561510 denotes active
T15615 3462-3467 UMLS/C0032214 denotes plays
T15614 4579-4585 UMLS/C1561509 denotes active
T15613 3731-3737 UMLS/C1561509 denotes active
T15612 3996-4006 UMLS/C0039215 denotes CD4+ cells
T15611 4319-4323 UMLS/C1552914 denotes hand
T15610 4579-4585 UMLS/C1561508 denotes active
T15609 3731-3737 UMLS/C1561508 denotes active
T15608 4579-4585 UMLS/C1561507 denotes active
T15607 3731-3737 UMLS/C1561507 denotes active
T15606 3593-3600 UMLS/C0557651 denotes studies
T15605 3593-3600 UMLS/C0947630 denotes studies
T15604 4514-4521 UMLS/C0039194 denotes T cells
T15603 4419-4426 UMLS/C0039194 denotes T cells
T15602 4396-4403 UMLS/C0039194 denotes T cells
T15601 4287-4294 UMLS/C0039194 denotes T cells
T15600 3913-3920 UMLS/C0039194 denotes T cells
T15599 3718-3725 UMLS/C0039194 denotes T cells
T15598 3247-3254 UMLS/C0039194 denotes T cells
T15597 3479-3483 UMLS/C1705809 denotes role
T15596 4626-4641 UMLS/C0031715 denotes phosphorylation
T15595 4345-4360 UMLS/C0031715 denotes phosphorylation
T15594 4246-4261 UMLS/C0031715 denotes phosphorylation
T15593 4196-4211 UMLS/C0031715 denotes phosphorylation
T15592 4095-4110 UMLS/C0031715 denotes phosphorylation
T15591 4039-4054 UMLS/C0031715 denotes phosphorylation
T15590 3819-3834 UMLS/C0031715 denotes phosphorylation
T15589 3682-3697 UMLS/C0031715 denotes phosphorylation
T15588 3220-3235 UMLS/C0031715 denotes phosphorylation
T15587 3559-3568 UMLS/C0750484 denotes confirmed
T15586 3408-3416 UMLS/C0205369 denotes specific
T15585 3479-3483 UMLS/C1705812 denotes role
T15584 3479-3483 UMLS/C1705810 denotes role
T15583 3479-3483 UMLS/C1705811 denotes role
T15582 4407-4413 UMLS/C1551394 denotes normal
T15581 3901-3907 UMLS/C1551394 denotes normal
T15580 4579-4585 UMLS/C1547419 denotes active
T15579 3731-3737 UMLS/C1547419 denotes active
T15578 3259-3270 UMLS/C1704675 denotes interaction
T15577 3462-3467 UMLS/C0331781 denotes plays
T15576 3767-3775 UMLS/C1550141 denotes controls
T15575 3938-3946 UMLS/C1979874 denotes contrast
T15574 3767-3775 UMLS/C1882979 denotes controls
T15823 3984-3992 UMLS/C1548221 denotes isolated
T15822 3578-3589 UMLS/C0024432 denotes macrophages
T15821 3397-3407 UMLS/C0024432 denotes Macrophage
T15820 3347-3353 UMLS/C0205275 denotes latent
T15819 4547-4557 UMLS/C1879547 denotes activation
T15818 4491-4500 UMLS/C1879547 denotes activated
T15817 4135-4144 UMLS/C1879547 denotes activated
T15816 3876-3886 UMLS/C1879547 denotes activation
T15815 3329-3339 UMLS/C1879547 denotes activation
T15814 3502-3529 UMLS/C1154987 denotes anti-inflammatory responses
T15813 4444-4451 UMLS/C1280519 denotes results
T15812 4433-4435 UMLS/C0450373 denotes 4a
T15811 3927-3929 UMLS/C0450373 denotes 4a
T15810 3593-3600 UMLS/C0008972 denotes studies
T15809 4301-4303 UMLS/C0450376 denotes 4c
T15808 4593-4604 UMLS/C0699792 denotes association
T15807 3930-3932 UMLS/C0450375 denotes 4b
T15806 3604-3621 UMLS/C1512032 denotes dominant-negative
T15805 3593-3600 UMLS/C0008976 denotes studies
T15804 3894-3897 UMLS/C0439232 denotes min
T15803 3767-3775 UMLS/C0332298 denotes controls
T15802 4015-4023 UMLS/C1705908 denotes patients
T15801 3741-3749 UMLS/C1705908 denotes patients
T15800 3408-3416 UMLS/C1552740 denotes specific
T15799 3894-3897 UMLS/C0702093 denotes min
T15798 4533-4540 UMLS/C0205263 denotes induced
T15797 4331-4338 UMLS/C0205263 denotes induced
T15796 4232-4239 UMLS/C0205263 denotes induced
T15795 3856-3863 UMLS/C0205263 denotes induced
T15794 3653-3662 UMLS/C0205263 denotes induction
T15793 3292-3299 UMLS/C0205263 denotes induces
T15792 4444-4451 UMLS/C0332294 denotes results
T15791 4444-4451 UMLS/C1274040 denotes results
T15790 4501-4505 UMLS/C1366753 denotes STAT
T15789 4501-4505 UMLS/C0205548 denotes STAT
T15788 3578-3589 UMLS/C1546706 denotes macrophages
T15787 3397-3407 UMLS/C1546706 denotes Macrophage
T15786 4267-4272 UMLS/C0243095 denotes found
T15785 4319-4323 UMLS/C1281583 denotes hand
T15784 3572-3577 UMLS/C0020156 denotes human
T15783 4407-4413 UMLS/C2347086 denotes normal
T15782 3901-3907 UMLS/C2347086 denotes normal
T15781 3864-3869 UMLS/C0687676 denotes after
T15780 4527-4532 UMLS/C1522550 denotes IL-10
T15779 4485-4490 UMLS/C1522550 denotes IL-10
T15778 4325-4330 UMLS/C1522550 denotes IL-10
T15777 4226-4231 UMLS/C1522550 denotes IL-10
T15776 4168-4173 UMLS/C1522550 denotes IL-10
T15775 3870-3875 UMLS/C1522550 denotes IL-10
T15774 3701-3706 UMLS/C1522550 denotes IL-10
T15773 3487-3492 UMLS/C1522550 denotes IL-10
T15772 3286-3291 UMLS/C1522550 denotes IL-10
T15771 3199-3204 UMLS/C1522550 denotes IL-10
T15770 4527-4532 UMLS/C1334098 denotes IL-10
T15769 4485-4490 UMLS/C1334098 denotes IL-10
T15768 4325-4330 UMLS/C1334098 denotes IL-10
T15767 4226-4231 UMLS/C1334098 denotes IL-10
T15766 4168-4173 UMLS/C1334098 denotes IL-10
T15765 3870-3875 UMLS/C1334098 denotes IL-10
T15764 3701-3706 UMLS/C1334098 denotes IL-10
T15763 3487-3492 UMLS/C1334098 denotes IL-10
T15762 3286-3291 UMLS/C1334098 denotes IL-10
T15761 3199-3204 UMLS/C1334098 denotes IL-10
T15760 3795-3811 UMLS/C0005863 denotes western blotting
T15759 4319-4323 UMLS/C0018563 denotes hand
T15758 3593-3600 UMLS/C2603343 denotes studies
T15757 3767-3775 UMLS/C0009932 denotes controls
T15756 3653-3662 UMLS/C1621983 denotes induction
T15755 3593-3600 UMLS/C2349977 denotes studies
T15754 4444-4451 UMLS/C1546471 denotes results
T15753 3274-3280 UMLS/C1149187 denotes IL-10R
T15752 3984-3992 UMLS/C1764827 denotes isolated
T15751 4080-4087 UMLS/C1292428 denotes 6 hours
T15750 4593-4604 UMLS/C1704771 denotes association
T15749 4593-4604 UMLS/C1704770 denotes association
T15748 4074-4079 UMLS/C0547043 denotes up to
T15747 3795-3811 UMLS/C0949466 denotes western blotting
T15746 3470-3478 UMLS/C1527180 denotes dominant
T15745 3984-3992 UMLS/C1546680 denotes isolated
T15744 4015-4023 UMLS/C0030705 denotes patients
T15743 3741-3749 UMLS/C0030705 denotes patients
T15742 4565-4575 UMLS/C0205216 denotes diminished
T15741 4115-4124 UMLS/C0205217 denotes augmented
T15740 3593-3600 UMLS/C1705923 denotes studies
T15739 4610-4619 UMLS/C0443318 denotes sustained
T15738 4180-4189 UMLS/C0443318 denotes sustained
T15737 4620-4625 UMLS/C1367307 denotes STAT3
T15736 4541-4546 UMLS/C1367307 denotes STAT3
T15735 4466-4471 UMLS/C1367307 denotes STAT3
T15734 4240-4245 UMLS/C1367307 denotes STAT3
T15733 4190-4195 UMLS/C1367307 denotes STAT3
T15732 4089-4094 UMLS/C1367307 denotes STAT3
T15731 4033-4038 UMLS/C1367307 denotes STAT3
T15730 3948-3953 UMLS/C1367307 denotes STAT3
T15729 3813-3818 UMLS/C1367307 denotes STAT3
T15728 3676-3681 UMLS/C1367307 denotes STAT3
T15727 3622-3627 UMLS/C1367307 denotes STAT3
T15726 3456-3461 UMLS/C1367307 denotes STAT3
T15725 3386-3391 UMLS/C1367307 denotes STAT3
T15724 3214-3219 UMLS/C1367307 denotes STAT3
T15723 4501-4505 UMLS/C1335960 denotes STAT
T15722 4407-4413 UMLS/C0439166 denotes normal
T15721 3901-3907 UMLS/C0439166 denotes normal
T15720 3767-3775 UMLS/C0243148 denotes controls
T15719 4593-4604 UMLS/C0004083 denotes association
T14712 2896-2904 UMLS/C0002778 denotes analysis
T14711 3136-3141 UMLS/C1149215 denotes IL-10
T14710 2678-2683 UMLS/C1149215 denotes IL-10
T14709 2629-2634 UMLS/C1149215 denotes IL-10
T14708 2439-2444 UMLS/C1149215 denotes IL-10
T14707 3050-3058 UMLS/C2587213 denotes controls
T14706 2853-2861 UMLS/C2587213 denotes controls
T14705 2599-2603 UMLS/C0035820 denotes role
T14704 2923-2925 UMLS/C0450364 denotes 3a
T14703 2664-2674 UMLS/C1522618 denotes resistance
T14702 2664-2674 UMLS/C0237834 denotes resistance
T14701 2582-2587 UMLS/C0600138 denotes plays
T14700 3142-3145 UMLS/C0454788 denotes may
T14699 2955-2965 UMLS/C0185117 denotes expression
T14698 2771-2781 UMLS/C0185117 denotes expression
T14697 2571-2581 UMLS/C0185117 denotes expression
T14696 2350-2360 UMLS/C0185117 denotes expression
T14695 3142-3145 UMLS/C0337876 denotes may
T14694 2419-2435 UMLS/C1523873 denotes receptor complex
T14693 2758-2770 UMLS/C0699040 denotes cell surface
T14692 2364-2376 UMLS/C0699040 denotes cell surface
T14691 3066-3073 UMLS/C1546471 denotes results
T14690 2551-2557 UMLS/C1149187 denotes IL-10R
T14689 2725-2732 UMLS/C0439801 denotes limited
T14688 2926-2928 UMLS/C0450365 denotes 3b
T14687 2483-2497 UMLS/C1517880 denotes ligand-binding
T14686 2607-2615 UMLS/C0007634 denotes cellular
T14685 3066-3073 UMLS/C1280519 denotes results
T14684 2590-2598 UMLS/C1511545 denotes critical
T14683 3050-3058 UMLS/C0332298 denotes controls
T14682 2853-2861 UMLS/C0332298 denotes controls
T14681 3016-3024 UMLS/C1705908 denotes patients
T14680 2827-2835 UMLS/C1705908 denotes patients
T14679 2725-2732 UMLS/C1549479 denotes limited
T14678 2607-2615 UMLS/C0178539 denotes cellular
T14677 2590-2598 UMLS/C1552746 denotes critical
T14676 2534-2543 UMLS/C0449432 denotes component
T14675 2498-2507 UMLS/C0449432 denotes component
T14674 3066-3073 UMLS/C0332294 denotes results
T14673 3066-3073 UMLS/C1274040 denotes results
T14672 2408-2418 UMLS/C0205245 denotes functional
T14671 2534-2543 UMLS/C1524073 denotes component
T14670 2498-2507 UMLS/C1524073 denotes component
T14669 3136-3141 UMLS/C1522550 denotes IL-10
T14668 2678-2683 UMLS/C1522550 denotes IL-10
T14667 2629-2634 UMLS/C1522550 denotes IL-10
T14666 2439-2444 UMLS/C1522550 denotes IL-10
T14665 3136-3141 UMLS/C1334098 denotes IL-10
T14664 2678-2683 UMLS/C1334098 denotes IL-10
T14663 2629-2634 UMLS/C1334098 denotes IL-10
T14662 2439-2444 UMLS/C1334098 denotes IL-10
T14661 2896-2904 UMLS/C0936012 denotes analysis
T14660 3050-3058 UMLS/C0009932 denotes controls
T14659 2853-2861 UMLS/C0009932 denotes controls
T14658 2590-2598 UMLS/C1547298 denotes critical
T14657 2475-2482 UMLS/C0205225 denotes primary
T14656 2684-2694 UMLS/C1628982 denotes inhibition
T14655 3149-3157 UMLS/C0684336 denotes impaired
T14654 3016-3024 UMLS/C0030705 denotes patients
T14653 2827-2835 UMLS/C0030705 denotes patients
T14652 3000-3009 UMLS/C0205217 denotes increased
T14651 2340-2349 UMLS/C0205217 denotes Increased
T14650 3091-3104 UMLS/C0175996 denotes intracellular
T14649 3050-3058 UMLS/C0243148 denotes controls
T14648 2853-2861 UMLS/C0243148 denotes controls
T14647 2475-2482 UMLS/C0439631 denotes primary
T14646 3016-3024 UMLS/C1578479 denotes patients
T14645 2827-2835 UMLS/C1578479 denotes patients
T14644 2955-2965 UMLS/C0017262 denotes expression
T14643 2771-2781 UMLS/C0017262 denotes expression
T14642 2571-2581 UMLS/C0017262 denotes expression
T14641 2350-2360 UMLS/C0017262 denotes expression
T14640 3016-3024 UMLS/C1578483 denotes patients
T14639 2827-2835 UMLS/C1578483 denotes patients
T14638 3016-3024 UMLS/C1578480 denotes patients
T14637 2827-2835 UMLS/C1578480 denotes patients
T14636 3016-3024 UMLS/C1578481 denotes patients
T14635 2827-2835 UMLS/C1578481 denotes patients
T14634 3016-3024 UMLS/C1578486 denotes patients
T14633 2827-2835 UMLS/C1578486 denotes patients
T14632 2866-2876 UMLS/C0521095 denotes determined
T14631 3016-3024 UMLS/C1578484 denotes patients
T14630 2827-2835 UMLS/C1578484 denotes patients
T14629 3016-3024 UMLS/C1578485 denotes patients
T14628 2827-2835 UMLS/C1578485 denotes patients
T14627 2408-2418 UMLS/C0542341 denotes functional
T14626 2590-2598 UMLS/C1579038 denotes critical
T14625 2616-2625 UMLS/C1706817 denotes responses
T14624 2408-2418 UMLS/C2700217 denotes functional
T14623 2880-2884 UMLS/C0806140 denotes flow
T14622 2457-2460 UMLS/C0205448 denotes two
T14621 3177-3183 UMLS/C1561511 denotes active
T14620 2817-2823 UMLS/C1561511 denotes active
T14619 3177-3183 UMLS/C1561512 denotes active
T14618 2817-2823 UMLS/C1561512 denotes active
T14617 3177-3183 UMLS/C1561513 denotes active
T14616 2817-2823 UMLS/C1561513 denotes active
T14615 2590-2598 UMLS/C1547308 denotes critical
T14614 2616-2625 UMLS/C1704632 denotes responses
T14613 3105-3132 UMLS/C0086982 denotes signal transduction pathway
T14612 2896-2904 UMLS/C1524024 denotes analysis
T14611 3016-3024 UMLS/C1550655 denotes patients
T14610 2827-2835 UMLS/C1550655 denotes patients
T14609 3177-3183 UMLS/C0205177 denotes active
T14608 2817-2823 UMLS/C0205177 denotes active
T14607 3050-3058 UMLS/C1547100 denotes controls
T14606 2853-2861 UMLS/C1547100 denotes controls
T14605 2599-2603 UMLS/C1704326 denotes role
T14604 2725-2732 UMLS/C0205189 denotes limited
T14603 2534-2543 UMLS/C1548799 denotes component
T14602 2498-2507 UMLS/C1548799 denotes component
T14601 2923-2925 UMLS/C1553635 denotes 3a
T14600 3177-3183 UMLS/C2347179 denotes active
T14599 2817-2823 UMLS/C2347179 denotes active
T14598 2664-2674 UMLS/C0683598 denotes resistance
T14597 3136-3141 UMLS/C0085295 denotes IL-10
T14596 2678-2683 UMLS/C0085295 denotes IL-10
T14595 2629-2634 UMLS/C0085295 denotes IL-10
T14594 2439-2444 UMLS/C0085295 denotes IL-10
T14593 2725-2732 UMLS/C1549649 denotes limited
T14592 2684-2694 UMLS/C0021467 denotes inhibition
T14591 2684-2694 UMLS/C0021469 denotes inhibition
T14590 3074-3081 UMLS/C1705535 denotes suggest
T14589 2722-2724 UMLS/C0319022 denotes to
T14588 2675-2677 UMLS/C0319022 denotes to
T14587 2641-2643 UMLS/C0319022 denotes To
T14586 2626-2628 UMLS/C0319022 denotes to
T14585 2644-2651 UMLS/C0332128 denotes examine
T14584 2534-2543 UMLS/C1179435 denotes component
T14583 2498-2507 UMLS/C1179435 denotes component
T14582 2725-2732 UMLS/C0449295 denotes limited
T14581 2918-2921 UMLS/C0349966 denotes Fig
T14580 3091-3104 UMLS/C0178719 denotes intracellular
T14579 3177-3183 UMLS/C1553875 denotes active
T14578 2817-2823 UMLS/C1553875 denotes active
T14577 3177-3183 UMLS/C1561510 denotes active
T14576 2817-2823 UMLS/C1561510 denotes active
T14575 2582-2587 UMLS/C0032214 denotes plays
T14574 3177-3183 UMLS/C1561509 denotes active
T14573 2817-2823 UMLS/C1561509 denotes active
T14572 3177-3183 UMLS/C1561508 denotes active
T14571 2817-2823 UMLS/C1561508 denotes active
T14570 3177-3183 UMLS/C1561507 denotes active
T14569 2817-2823 UMLS/C1561507 denotes active
T14568 3000-3009 UMLS/C0442805 denotes increased
T14567 2340-2349 UMLS/C0442805 denotes Increased
T14566 3166-3173 UMLS/C0039194 denotes T cells
T14565 2974-2981 UMLS/C0039194 denotes T cells
T14564 2804-2811 UMLS/C0039194 denotes T cells
T14563 2706-2713 UMLS/C0039194 denotes T cells
T14562 2396-2403 UMLS/C0039194 denotes T cells
T14561 3000-3009 UMLS/C0442808 denotes increased
T14560 2340-2349 UMLS/C0442808 denotes Increased
T14559 2599-2603 UMLS/C1705809 denotes role
T14558 2599-2603 UMLS/C1705812 denotes role
T14557 2733-2752 UMLS/C0597360 denotes receptor expression
T14556 2534-2543 UMLS/C0729650 denotes component
T14555 2498-2507 UMLS/C0729650 denotes component
T14554 2599-2603 UMLS/C1705810 denotes role
T14553 2599-2603 UMLS/C1705811 denotes role
T14552 2590-2598 UMLS/C1551396 denotes critical
T14551 2725-2732 UMLS/C2349209 denotes limited
T14550 3177-3183 UMLS/C1547419 denotes active
T14549 2817-2823 UMLS/C1547419 denotes active
T14548 2582-2587 UMLS/C0331781 denotes plays
T14547 2934-2943 UMLS/C0522510 denotes intensity
T14546 2534-2543 UMLS/C1705248 denotes component
T14545 2498-2507 UMLS/C1705248 denotes component
T14544 2616-2625 UMLS/C0871261 denotes responses
T14543 3025-3033 UMLS/C1707455 denotes compared
T14542 3050-3058 UMLS/C1550141 denotes controls
T14541 2853-2861 UMLS/C1550141 denotes controls
T14540 3050-3058 UMLS/C1882979 denotes controls
T14539 2853-2861 UMLS/C1882979 denotes controls
T14538 3149-3157 UMLS/C0221099 denotes impaired
T12795 2022-2037 UMLS/C1819447 denotes was not affect
T12794 1874-1889 UMLS/C1819447 denotes by CD4+ T cell
T12793 213-217 UMLS/C0323983 denotes his
T12792 1172-1178 UMLS/C0444497 denotes CRP l
T12791 1458-1468 UMLS/C1548180 denotes was signif
T12790 1352-1362 UMLS/C1548180 denotes without I
T12789 1021-1031 UMLS/C1548180 denotes ion by CD4
T12788 680-690 UMLS/C1548180 denotes duction by
T12787 619-629 UMLS/C1548180 denotes oduction w
T12786 50-60 UMLS/C1548180 denotes roduction
T12785 1920-1924 UMLS/C1332709 denotes ion
T12784 1062-1066 UMLS/C1332709 denotes stim
T12783 241-245 UMLS/C1332709 denotes D28
T12782 84-88 UMLS/C1332709 denotes D28
T12781 136-143 UMLS/C0003320 denotes ntigen-
T12780 2171-2179 UMLS/C2587213 denotes 13.7%;
T12779 2001-2009 UMLS/C2587213 denotes arly, IL
T12778 1653-1661 UMLS/C2587213 denotes 8 ± 7.9%
T12777 1569-1577 UMLS/C2587213 denotes ercentag
T12776 1280-1288 UMLS/C2587213 denotes There w
T12775 465-473 UMLS/C2587213 denotes ontrols
T12774 1239-1242 UMLS/C1413716 denotes <
T12773 1180-1183 UMLS/C1413716 denotes el
T12772 766-769 UMLS/C1299352 denotes as
T12771 1752-1758 UMLS/C1299351 denotes of IFN
T12770 204-212 UMLS/C1260953 denotes uppress
T12769 9-19 UMLS/C0237834 denotes Resistance
T12768 1239-1242 UMLS/C0006560 denotes <
T12767 1180-1183 UMLS/C0006560 denotes el
T12766 2060-2065 UMLS/C0439275 denotes RA pa
T12765 1797-1802 UMLS/C0439275 denotes n did
T12764 1102-1107 UMLS/C0439275 denotes L-10
T12763 976-981 UMLS/C0439275 denotes We t
T12762 885-890 UMLS/C0439275 denotes l IL-
T12761 775-780 UMLS/C0439275 denotes ml IL
T12760 537-545 UMLS/C0003241 denotes ntibody
T12759 834-845 UMLS/C1546944 denotes nificant am
T12758 1818-1824 UMLS/C0205307 denotes ells (
T12757 704-710 UMLS/C0205307 denotes mal CD
T12756 846-853 UMLS/C1265611 denotes unts of
T12755 1906-1911 UMLS/C0231290 denotes D28 c
T12754 1048-1053 UMLS/C0231290 denotes D3 an
T12753 601-606 UMLS/C0439227 denotes ours,
T12752 906-913 UMLS/C0205289 denotes mal but
T12751 2229-2236 UMLS/C1546471 denotes that RA
T12750 1487-1494 UMLS/C0439801 denotes the act
T12749 1304-1329 UMLS/C0237881 denotes ally significant differen
T12748 1920-1924 UMLS/C1426202 denotes ion
T12747 1062-1066 UMLS/C1426202 denotes stim
T12746 241-245 UMLS/C1426202 denotes D28
T12745 84-88 UMLS/C1426202 denotes D28
T12744 103-110 UMLS/C1705987 denotes athway
T12743 2042-2045 UMLS/C1518422 denotes 1
T12742 2171-2179 UMLS/C0332298 denotes 13.7%;
T12741 2001-2009 UMLS/C0332298 denotes arly, IL
T12740 1653-1661 UMLS/C0332298 denotes 8 ± 7.9%
T12739 1569-1577 UMLS/C0332298 denotes ercentag
T12738 1280-1288 UMLS/C0332298 denotes There w
T12737 465-473 UMLS/C0332298 denotes ontrols
T12736 144-152 UMLS/C1552740 denotes pecific
T12735 2078-2086 UMLS/C1705908 denotes ntage de
T12734 1977-1985 UMLS/C1705908 denotes healthy
T12733 1734-1742 UMLS/C1705908 denotes ced high
T12732 1120-1128 UMLS/C1705908 denotes s with a
T12731 418-426 UMLS/C1705908 denotes atients
T12730 1693-1704 UMLS/C0686907 denotes D4+ T cells
T12729 1551-1556 UMLS/C1705429 denotes ealth
T12728 1512-1517 UMLS/C1705429 denotes mpare
T12727 1395-1401 UMLS/C1705429 denotes g. 2a)
T12726 1551-1556 UMLS/C1705428 denotes ealth
T12725 1512-1517 UMLS/C1705428 denotes mpare
T12724 1395-1401 UMLS/C1705428 denotes g. 2a)
T12723 766-769 UMLS/C1611820 denotes as
T12722 1752-1758 UMLS/C0205250 denotes of IFN
T12721 766-769 UMLS/C0205251 denotes as
T12720 766-769 UMLS/C0234886 denotes as
T12719 2229-2236 UMLS/C0332294 denotes that RA
T12718 2229-2236 UMLS/C1274040 denotes that RA
T12717 275-282 UMLS/C0243122 denotes inding
T12716 1625-1633 UMLS/C0205254 denotes 45.6 ±
T12715 1539-1547 UMLS/C0205254 denotes group a
T12714 1818-1824 UMLS/C2347086 denotes ells (
T12713 704-710 UMLS/C2347086 denotes mal CD
T12712 748-762 UMLS/C0086045 denotes centrations as
T12711 570-584 UMLS/C0086045 denotes oncentrations
T12710 1239-1242 UMLS/C1826658 denotes <
T12709 1180-1183 UMLS/C1826658 denotes el
T12708 931-941 UMLS/C1628982 denotes bition by
T12707 29-39 UMLS/C1628982 denotes inhibition
T12706 2099-2107 UMLS/C0205216 denotes ± 13.8%)
T12705 1590-1598 UMLS/C0205216 denotes ctive RA
T12704 2088-2098 UMLS/C0439165 denotes ease, -2.1
T12703 1579-1589 UMLS/C0439165 denotes decrease:
T12702 1818-1824 UMLS/C0439166 denotes ells (
T12701 704-710 UMLS/C0439166 denotes mal CD
T12700 103-110 UMLS/C1704259 denotes athway
T12699 1551-1556 UMLS/C0439745 denotes ealth
T12698 1512-1517 UMLS/C0439745 denotes mpare
T12697 1395-1401 UMLS/C0439745 denotes g. 2a)
T12696 2171-2179 UMLS/C0243148 denotes 13.7%;
T12695 2001-2009 UMLS/C0243148 denotes arly, IL
T12694 1653-1661 UMLS/C0243148 denotes 8 ± 7.9%
T12693 1569-1577 UMLS/C0243148 denotes ercentag
T12692 1280-1288 UMLS/C0243148 denotes There w
T12691 465-473 UMLS/C0243148 denotes ontrols
T12690 191-194 UMLS/C0344312 denotes an
T12689 1239-1242 UMLS/C1879974 denotes <
T12688 1180-1183 UMLS/C1879974 denotes el
T12687 218-226 UMLS/C1706817 denotes esponse
T12686 246-270 UMLS/C1519726 denotes yrosine phosphorylation
T12685 1389-1394 UMLS/C0205449 denotes ps (F
T12684 451-456 UMLS/C0205449 denotes hree
T12683 412-417 UMLS/C0205449 denotes hree
T12682 191-194 UMLS/C0006823 denotes an
T12681 1172-1178 UMLS/C1706309 denotes CRP l
T12680 2078-2086 UMLS/C1550655 denotes ntage de
T12679 1977-1985 UMLS/C1550655 denotes healthy
T12678 1734-1742 UMLS/C1550655 denotes ced high
T12677 1120-1128 UMLS/C1550655 denotes s with a
T12676 418-426 UMLS/C1550655 denotes atients
T12675 1551-1556 UMLS/C1552839 denotes ealth
T12674 1512-1517 UMLS/C1552839 denotes mpare
T12673 1395-1401 UMLS/C1552839 denotes g. 2a)
T12672 1551-1556 UMLS/C1257890 denotes ealth
T12671 1512-1517 UMLS/C1257890 denotes mpare
T12670 1395-1401 UMLS/C1257890 denotes g. 2a)
T12669 2207-2212 UMLS/C1515187 denotes hese
T12668 2171-2179 UMLS/C1547100 denotes 13.7%;
T12667 2001-2009 UMLS/C1547100 denotes arly, IL
T12666 1653-1661 UMLS/C1547100 denotes 8 ± 7.9%
T12665 1569-1577 UMLS/C1547100 denotes ercentag
T12664 1280-1288 UMLS/C1547100 denotes There w
T12663 465-473 UMLS/C1547100 denotes ontrols
T12662 601-606 UMLS/C0564385 denotes ours,
T12661 1752-1758 UMLS/C1522410 denotes of IFN
T12660 275-282 UMLS/C1689898 denotes inding
T12659 634-642 UMLS/C0079809 denotes asured b
T12658 1487-1494 UMLS/C1549649 denotes the act
T12657 1818-1824 UMLS/C1873497 denotes ells (
T12656 704-710 UMLS/C1873497 denotes mal CD
T12655 931-941 UMLS/C0021467 denotes bition by
T12654 29-39 UMLS/C0021467 denotes inhibition
T12653 1421-1431 UMLS/C0021469 denotes effect of
T12652 931-941 UMLS/C0021469 denotes bition by
T12651 735-744 UMLS/C0021469 denotes ibited at
T12650 230-240 UMLS/C0021469 denotes nhibiting
T12649 29-39 UMLS/C0021469 denotes inhibition
T12648 1946-1954 UMLS/C0150312 denotes 10 in ac
T12647 1783-1791 UMLS/C0150312 denotes g/ml IL-
T12646 1088-1096 UMLS/C0150312 denotes e of 1 n
T12645 871-879 UMLS/C0150312 denotes ence of
T12644 1150-1158 UMLS/C0439064 denotes e inflam
T12643 1912-1915 UMLS/C2698592 denotes sti
T12642 1054-1057 UMLS/C2698592 denotes CD
T12641 537-545 UMLS/C1621287 denotes ntibody
T12640 1487-1494 UMLS/C0449295 denotes the act
T12639 1839-1842 UMLS/C0349966 denotes dit
T12638 1678-1681 UMLS/C0349966 denotes co
T12637 1403-1406 UMLS/C0349966 denotes but
T12636 665-668 UMLS/C0349966 denotes g.
T12635 1967-1973 UMLS/C1553875 denotes nts an
T12634 1724-1730 UMLS/C1553875 denotes ents p
T12633 1600-1606 UMLS/C1553875 denotes 2.9 ±
T12632 1502-1508 UMLS/C1553875 denotes roup a
T12534 479-489 UMLS/C1948023 denotes timulated
T12533 2325-2330 UMLS/C1334098 denotes activ
T12532 2066-2071 UMLS/C1334098 denotes ients
T12531 1958-1963 UMLS/C1334098 denotes RA p
T12530 1803-1808 UMLS/C1334098 denotes norma
T12529 1442-1447 UMLS/C1334098 denotes FN-γ
T12528 1371-1376 UMLS/C1334098 denotes g the
T12527 1108-1113 UMLS/C1334098 denotes n RA
T12526 945-950 UMLS/C1334098 denotes 0 was
T12525 891-896 UMLS/C1334098 denotes 0, an
T12524 781-786 UMLS/C1334098 denotes 10. H
T12523 1108-1113 UMLS/C1522550 denotes n RA
T12522 945-950 UMLS/C1522550 denotes 0 was
T12521 891-896 UMLS/C1522550 denotes 0, an
T12520 781-786 UMLS/C1522550 denotes 10. H
T12519 588-593 UMLS/C1334098 denotes L-10
T12518 375-380 UMLS/C1334098 denotes L-10,
T12517 185-190 UMLS/C1334098 denotes L-10
T12516 23-28 UMLS/C1334098 denotes IL-10
T12515 2088-2098 UMLS/C1549488 denotes ease, -2.1
T12514 1579-1589 UMLS/C1549488 denotes decrease:
T12513 1551-1556 UMLS/C1552516 denotes ealth
T12512 1512-1517 UMLS/C1552516 denotes mpare
T12511 1395-1401 UMLS/C1552516 denotes g. 2a)
T12510 2213-2221 UMLS/C1883357 denotes esults i
T12509 2171-2179 UMLS/C0009932 denotes 13.7%;
T12508 2001-2009 UMLS/C0009932 denotes arly, IL
T12507 1653-1661 UMLS/C0009932 denotes 8 ± 7.9%
T12506 1569-1577 UMLS/C0009932 denotes ercentag
T12505 1280-1288 UMLS/C0009932 denotes There w
T12504 465-473 UMLS/C0009932 denotes ontrols
T12503 2099-2107 UMLS/C0547047 denotes ± 13.8%)
T12502 1590-1598 UMLS/C0547047 denotes ctive RA
T12501 646-651 UMLS/C0014441 denotes ISA.
T12500 1752-1758 UMLS/C1561957 denotes of IFN
T12499 1752-1758 UMLS/C1561958 denotes of IFN
T12498 2078-2086 UMLS/C0030705 denotes ntage de
T12497 1977-1985 UMLS/C0030705 denotes healthy
T12496 1734-1742 UMLS/C0030705 denotes ced high
T12495 1120-1128 UMLS/C0030705 denotes s with a
T12494 418-426 UMLS/C0030705 denotes atients
T12493 1946-1954 UMLS/C0392148 denotes 10 in ac
T12492 1783-1791 UMLS/C0392148 denotes g/ml IL-
T12491 1088-1096 UMLS/C0392148 denotes e of 1 n
T12490 871-879 UMLS/C0392148 denotes ence of
T12489 382-390 UMLS/C1998793 denotes urified
T12488 1239-1242 UMLS/C0201657 denotes <
T12487 1180-1183 UMLS/C0201657 denotes el
T12486 818-822 UMLS/C1299581 denotes e to
T12485 1625-1633 UMLS/C1705605 denotes 45.6 ±
T12484 1539-1547 UMLS/C1705605 denotes group a
T12483 2046-2054 UMLS/C1314939 denotes g/ml IL-
T12482 2078-2086 UMLS/C1578479 denotes ntage de
T12481 1977-1985 UMLS/C1578479 denotes healthy
T12480 1734-1742 UMLS/C1578479 denotes ced high
T12479 1120-1128 UMLS/C1578479 denotes s with a
T12478 418-426 UMLS/C1578479 denotes atients
T12477 918-930 UMLS/C1444661 denotes complete inh
T12476 2078-2086 UMLS/C1578483 denotes ntage de
T12475 1977-1985 UMLS/C1578483 denotes healthy
T12474 1734-1742 UMLS/C1578483 denotes ced high
T12473 1120-1128 UMLS/C1578483 denotes s with a
T12472 418-426 UMLS/C1578483 denotes atients
T12471 2078-2086 UMLS/C1578480 denotes ntage de
T12470 1977-1985 UMLS/C1578480 denotes healthy
T12469 1734-1742 UMLS/C1578480 denotes ced high
T12468 1120-1128 UMLS/C1578480 denotes s with a
T12467 418-426 UMLS/C1578480 denotes atients
T12466 2078-2086 UMLS/C1578481 denotes ntage de
T12465 1977-1985 UMLS/C1578481 denotes healthy
T12464 1734-1742 UMLS/C1578481 denotes ced high
T12463 1120-1128 UMLS/C1578481 denotes s with a
T12462 418-426 UMLS/C1578481 denotes atients
T12461 1912-1915 UMLS/C0108779 denotes sti
T12460 1054-1057 UMLS/C0108779 denotes CD
T12459 2078-2086 UMLS/C1578486 denotes ntage de
T12458 1977-1985 UMLS/C1578486 denotes healthy
T12457 1734-1742 UMLS/C1578486 denotes ced high
T12456 1120-1128 UMLS/C1578486 denotes s with a
T12455 418-426 UMLS/C1578486 denotes atients
T12454 2078-2086 UMLS/C1578484 denotes ntage de
T12453 1977-1985 UMLS/C1578484 denotes healthy
T12452 1977-1985 UMLS/C1578485 denotes healthy
T12451 1734-1742 UMLS/C1578485 denotes ced high
T12450 1120-1128 UMLS/C1578485 denotes s with a
T12449 418-426 UMLS/C1578485 denotes atients
T12448 2088-2098 UMLS/C1561533 denotes ease, -2.1
T12447 1579-1589 UMLS/C1561533 denotes decrease:
T12446 1141-1148 UMLS/C0012634 denotes (multi
T12445 537-545 UMLS/C0021027 denotes ntibody
T12444 1172-1178 UMLS/C0392905 denotes CRP l
T12443 1172-1178 UMLS/C1269611 denotes CRP l
T12442 1734-1742 UMLS/C1578484 denotes ced high
T12441 1120-1128 UMLS/C1578484 denotes s with a
T12440 1967-1973 UMLS/C1561511 denotes nts an
T12439 1724-1730 UMLS/C1561511 denotes ents p
T12438 418-426 UMLS/C1578484 denotes atients
T12437 2078-2086 UMLS/C1578485 denotes ntage de
T12436 1600-1606 UMLS/C1561511 denotes 2.9 ±
T12435 1502-1508 UMLS/C1561511 denotes roup a
T12434 1134-1140 UMLS/C1561513 denotes diseas
T12433 432-438 UMLS/C1561513 denotes ctive
T12432 2237-2245 UMLS/C1444656 denotes CD4+ T c
T12431 766-769 UMLS/C0441994 denotes as
T12430 218-226 UMLS/C1704632 denotes esponse
T12429 846-853 UMLS/C1561574 denotes unts of
T12428 275-282 UMLS/C1167622 denotes inding
T12427 766-769 UMLS/C1708760 denotes as
T12426 195-203 UMLS/C1947931 denotes irectly
T12425 1551-1556 UMLS/C1561557 denotes ealth
T12424 1512-1517 UMLS/C1561557 denotes mpare
T12423 1395-1401 UMLS/C1561557 denotes g. 2a)
T12422 1967-1973 UMLS/C0205177 denotes nts an
T12421 1724-1730 UMLS/C0205177 denotes ents p
T12420 1600-1606 UMLS/C0205177 denotes 2.9 ±
T12419 1502-1508 UMLS/C0205177 denotes roup a
T12418 1134-1140 UMLS/C0205177 denotes diseas
T12417 432-438 UMLS/C0205177 denotes ctive
T12416 1625-1633 UMLS/C1608264 denotes 45.6 ±
T12415 1539-1547 UMLS/C1608264 denotes group a
T12414 766-769 UMLS/C1619811 denotes as
T12413 1625-1633 UMLS/C1608263 denotes 45.6 ±
T12412 1539-1547 UMLS/C1608263 denotes group a
T12411 1487-1494 UMLS/C0205189 denotes the act
T12410 1239-1242 UMLS/C1413766 denotes <
T12409 1180-1183 UMLS/C1413766 denotes el
T12408 9-19 UMLS/C0683598 denotes Resistance
T12407 1967-1973 UMLS/C2347179 denotes nts an
T12406 1724-1730 UMLS/C2347179 denotes ents p
T12405 1600-1606 UMLS/C2347179 denotes 2.9 ±
T12404 1502-1508 UMLS/C2347179 denotes roup a
T12403 1134-1140 UMLS/C2347179 denotes diseas
T12402 432-438 UMLS/C2347179 denotes ctive
T12401 2325-2330 UMLS/C0085295 denotes activ
T12400 2066-2071 UMLS/C0085295 denotes ients
T12399 1958-1963 UMLS/C0085295 denotes RA p
T12398 1803-1808 UMLS/C0085295 denotes norma
T12397 1442-1447 UMLS/C0085295 denotes FN-γ
T12396 1371-1376 UMLS/C0085295 denotes g the
T12395 1108-1113 UMLS/C0085295 denotes n RA
T12394 945-950 UMLS/C0085295 denotes 0 was
T12393 891-896 UMLS/C0085295 denotes 0, an
T12392 781-786 UMLS/C0085295 denotes 10. H
T12391 588-593 UMLS/C0085295 denotes L-10
T12390 375-380 UMLS/C0085295 denotes L-10,
T12389 185-190 UMLS/C0085295 denotes L-10
T12388 23-28 UMLS/C0085295 denotes IL-10
T12387 766-769 UMLS/C1548802 denotes as
T12386 286-315 UMLS/C0044602 denotes hosphatidylinositol 3-kinase
T12385 2152-2159 UMLS/C0392756 denotes hy cont
T12384 2099-2107 UMLS/C0392756 denotes ± 13.8%)
T12383 1590-1598 UMLS/C0392756 denotes ctive RA
T12382 1818-1824 UMLS/C1704701 denotes ells (
T12381 704-710 UMLS/C1704701 denotes mal CD
T12380 1413-1416 UMLS/C0005341 denotes hib
T12379 914-917 UMLS/C0005341 denotes not
T12378 2291-2293 UMLS/C0319022 denotes la
T12377 823-825 UMLS/C0319022 denotes pr
T12376 372-374 UMLS/C0319022 denotes o
T12375 322-324 UMLS/C0319022 denotes o
T12374 20-22 UMLS/C0319022 denotes to
T12373 562-569 UMLS/C1720119 denotes iluted
T12372 1551-1556 UMLS/C1522242 denotes ealth
T12371 1512-1517 UMLS/C1522242 denotes mpare
T12370 1395-1401 UMLS/C1522242 denotes g. 2a)
T12369 634-642 UMLS/C0444706 denotes asured b
T12368 2046-2054 UMLS/C0392760 denotes g/ml IL-
T12367 1818-1824 UMLS/C1550457 denotes ells (
T12366 704-710 UMLS/C1550457 denotes mal CD
T12365 1134-1140 UMLS/C1561511 denotes diseas
T12364 1844-1846 UMLS/C1553634 denotes n,
T12363 432-438 UMLS/C1561511 denotes ctive
T12362 1967-1973 UMLS/C1561512 denotes nts an
T12361 1724-1730 UMLS/C1561512 denotes ents p
T12360 1600-1606 UMLS/C1561512 denotes 2.9 ±
T12359 1502-1508 UMLS/C1561512 denotes roup a
T12358 1134-1140 UMLS/C1561512 denotes diseas
T12357 432-438 UMLS/C1561512 denotes ctive
T12356 1408-1410 UMLS/C1553634 denotes he
T12355 1967-1973 UMLS/C1561510 denotes nts an
T12354 1967-1973 UMLS/C1561513 denotes nts an
T12353 1724-1730 UMLS/C1561513 denotes ents p
T12352 1600-1606 UMLS/C1561513 denotes 2.9 ±
T12351 1502-1508 UMLS/C1561513 denotes roup a
T12350 1724-1730 UMLS/C1561510 denotes ents p
T12349 1600-1606 UMLS/C1561510 denotes 2.9 ±
T12348 1502-1508 UMLS/C1561510 denotes roup a
T12347 1134-1140 UMLS/C1561510 denotes diseas
T12346 432-438 UMLS/C1561510 denotes ctive
T12345 1967-1973 UMLS/C1561509 denotes nts an
T12344 1724-1730 UMLS/C1561509 denotes ents p
T12343 1600-1606 UMLS/C1561509 denotes 2.9 ±
T12342 1502-1508 UMLS/C1561509 denotes roup a
T12341 1134-1140 UMLS/C1561509 denotes diseas
T12340 432-438 UMLS/C1561509 denotes ctive
T12339 1967-1973 UMLS/C1561508 denotes nts an
T12338 1724-1730 UMLS/C1561508 denotes ents p
T12337 1600-1606 UMLS/C1561508 denotes 2.9 ±
T12336 1502-1508 UMLS/C1561508 denotes roup a
T12335 1134-1140 UMLS/C1561508 denotes diseas
T12334 432-438 UMLS/C1561508 denotes ctive
T12333 1159-1171 UMLS/C0333348 denotes atory joints
T12332 1967-1973 UMLS/C1561507 denotes nts an
T12331 1724-1730 UMLS/C1561507 denotes ents p
T12330 1600-1606 UMLS/C1561507 denotes 2.9 ±
T12329 1502-1508 UMLS/C1561507 denotes roup a
T12328 1134-1140 UMLS/C1561507 denotes diseas
T12327 432-438 UMLS/C1561507 denotes ctive
T12326 834-845 UMLS/C0750502 denotes nificant am
T12325 153-179 UMLS/C1817749 denotes -cell cytokine production,
T12324 275-282 UMLS/C1145667 denotes inding
T12323 1818-1824 UMLS/C1551394 denotes ells (
T12322 704-710 UMLS/C1551394 denotes mal CD
T12321 1487-1494 UMLS/C2349209 denotes the act
T12320 275-282 UMLS/C2349209 denotes inding
T12319 1967-1973 UMLS/C1547419 denotes nts an
T12631 1134-1140 UMLS/C1553875 denotes diseas
T12630 432-438 UMLS/C1553875 denotes ctive
T12629 2099-2107 UMLS/C0442797 denotes ± 13.8%)
T12628 1590-1598 UMLS/C0442797 denotes ctive RA
T12627 1852-1860 UMLS/C1883712 denotes mpared I
T12626 2259-2266 UMLS/C0039194 denotes ss susc
T12625 1898-1905 UMLS/C0039194 denotes D3 and
T12624 1830-1837 UMLS/C0039194 denotes a). In
T12623 1711-1718 UMLS/C0039194 denotes ctive R
T12622 1040-1047 UMLS/C0039194 denotes after
T12621 805-812 UMLS/C0039194 denotes ells we
T12620 716-723 UMLS/C0039194 denotes ells wa
T12619 399-406 UMLS/C0039194 denotes cells
T12618 364-371 UMLS/C0039194 denotes cells
T12617 72-79 UMLS/C0039194 denotes cells
T12616 1216-1237 UMLS/C0544452 denotes in remission, CRP lev
T12615 1207-1223 UMLS/C0544452 denotes disease (in remi
T12614 144-152 UMLS/C0205369 denotes pecific
T12613 2207-2212 UMLS/C1883727 denotes hese
T12612 1759-1765 UMLS/C0456079 denotes γ in t
T12611 1243-1248 UMLS/C0456079 denotes 0 mg/
T12610 1184-1189 UMLS/C0456079 denotes 10 m
T12609 1004-1010 UMLS/C0456079 denotes of IF
T12608 126-135 UMLS/C1704419 denotes ffective
T12607 1920-1924 UMLS/C0075747 denotes ion
T12606 1062-1066 UMLS/C0075747 denotes stim
T12605 241-245 UMLS/C0075747 denotes D28
T12604 84-88 UMLS/C0075747 denotes D28
T12603 1172-1178 UMLS/C0022417 denotes CRP l
T12602 1865-1873 UMLS/C1707455 denotes roductio
T12601 1521-1529 UMLS/C1707455 denotes th the i
T12600 991-999 UMLS/C1707455 denotes ed the l
T12599 1330-1341 UMLS/C1705242 denotes es in IFN-γ
T12598 2171-2179 UMLS/C1550141 denotes 13.7%;
T12597 2001-2009 UMLS/C1550141 denotes arly, IL
T12596 1653-1661 UMLS/C1550141 denotes 8 ± 7.9%
T12595 1569-1577 UMLS/C1550141 denotes ercentag
T12594 1280-1288 UMLS/C1550141 denotes There w
T12593 465-473 UMLS/C1550141 denotes ontrols
T12592 748-762 UMLS/C1446561 denotes centrations as
T12591 570-584 UMLS/C1446561 denotes oncentrations
T12590 1330-1341 UMLS/C1705241 denotes es in IFN-γ
T12589 2325-2330 UMLS/C1149215 denotes activ
T12588 2066-2071 UMLS/C1149215 denotes ients
T12587 1958-1963 UMLS/C1149215 denotes RA p
T12586 1803-1808 UMLS/C1149215 denotes norma
T12585 1442-1447 UMLS/C1149215 denotes FN-γ
T12584 1371-1376 UMLS/C1149215 denotes g the
T12583 1108-1113 UMLS/C1149215 denotes n RA
T12582 945-950 UMLS/C1149215 denotes 0 was
T12581 891-896 UMLS/C1149215 denotes 0, an
T12580 781-786 UMLS/C1149215 denotes 10. H
T12579 588-593 UMLS/C1149215 denotes L-10
T12578 375-380 UMLS/C1149215 denotes L-10,
T12577 185-190 UMLS/C1149215 denotes L-10
T12576 23-28 UMLS/C1149215 denotes IL-10
T12575 1844-1846 UMLS/C0450353 denotes n,
T12574 1408-1410 UMLS/C0450353 denotes he
T12573 1683-1685 UMLS/C0450354 denotes eq
T12572 505-522 UMLS/C0879551 denotes nti-CD3 antibody
T12571 1759-1765 UMLS/C0441889 denotes γ in t
T12570 1243-1248 UMLS/C0441889 denotes 0 mg/
T12569 1184-1189 UMLS/C0441889 denotes 10 m
T12568 1004-1010 UMLS/C0441889 denotes of IF
T12567 634-642 UMLS/C1879489 denotes asured b
T12566 9-19 UMLS/C1522618 denotes Resistance
T12565 325-333 UMLS/C0220825 denotes valuate
T12564 955-963 UMLS/C1706701 denotes ined at
T12563 2315-2321 UMLS/C2348382 denotes uring
T12562 1432-1438 UMLS/C2348382 denotes IL-10
T12561 766-769 UMLS/C1550472 denotes as
T12560 2279-2290 UMLS/C0231204 denotes e immunoreg
T12559 1551-1556 UMLS/C0441833 denotes ealth
T12558 1512-1517 UMLS/C0441833 denotes mpare
T12557 1395-1401 UMLS/C0441833 denotes g. 2a)
T12556 694-703 UMLS/C1879547 denotes ivated no
T12555 2229-2236 UMLS/C1280519 denotes that RA
T12554 818-822 UMLS/C0085732 denotes e to
T12553 955-963 UMLS/C1301820 denotes ined at
T12552 2315-2321 UMLS/C1280500 denotes uring
T12551 1432-1438 UMLS/C1280500 denotes IL-10
T12550 634-642 UMLS/C0242485 denotes asured b
T12549 1487-1494 UMLS/C1549479 denotes the act
T12548 562-569 UMLS/C1948037 denotes iluted
T12547 2046-2054 UMLS/C0001721 denotes g/ml IL-
T12546 1906-1911 UMLS/C0687676 denotes D28 c
T12545 1048-1053 UMLS/C0687676 denotes D3 an
T12544 2325-2330 UMLS/C1522550 denotes activ
T12543 2066-2071 UMLS/C1522550 denotes ients
T12542 1958-1963 UMLS/C1522550 denotes RA p
T12541 1803-1808 UMLS/C1522550 denotes norma
T12540 1442-1447 UMLS/C1522550 denotes FN-γ
T12539 1371-1376 UMLS/C1522550 denotes g the
T12538 588-593 UMLS/C1522550 denotes L-10
T12537 375-380 UMLS/C1522550 denotes L-10,
T12536 185-190 UMLS/C1522550 denotes L-10
T12535 23-28 UMLS/C1522550 denotes IL-10
T12318 1724-1730 UMLS/C1547419 denotes ents p
T12317 1600-1606 UMLS/C1547419 denotes 2.9 ±
T12316 1502-1508 UMLS/C1547419 denotes roup a
T12315 1134-1140 UMLS/C1547419 denotes diseas
T12314 432-438 UMLS/C1547419 denotes ctive
T12313 1625-1633 UMLS/C1547420 denotes 45.6 ±
T12312 1539-1547 UMLS/C1547420 denotes group a
T12311 218-226 UMLS/C0871261 denotes esponse
T12310 2171-2179 UMLS/C1882979 denotes 13.7%;
T12309 2001-2009 UMLS/C1882979 denotes arly, IL
T12308 1653-1661 UMLS/C1882979 denotes 8 ± 7.9%
T12307 1569-1577 UMLS/C1882979 denotes ercentag
T12306 1280-1288 UMLS/C1882979 denotes There w
T12305 465-473 UMLS/C1882979 denotes ontrols

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T18916 7082-7087 NN denotes cells
T20802 7831-7834 CC denotes and
T20801 7825-7830 NN denotes SOCS1
T20800 7822-7824 IN denotes of
T20799 7815-7821 NN denotes levels
T20798 7811-7814 DT denotes the
T20797 7809-7810 -COMMA- denotes ,
T20796 7804-7809 NN denotes cells
T20795 7802-7803 NN denotes T
T20794 7797-7801 JJ denotes CD4+
T20793 7794-7796 NN denotes RA
T20792 7791-7793 IN denotes of
T20791 7780-7790 NN denotes activation
T20790 7774-7779 NN denotes STAT3
T20789 7760-7773 JJ denotes IL-10-induced
T20788 7750-7759 JJ denotes defective
T20787 7746-7749 DT denotes the
T20786 7743-7745 IN denotes in
T20785 7734-7742 VB denotes involved
T20784 7729-7733 VB denotes were
T20783 7723-7728 NN denotes SOCSs
T20782 7715-7722 IN denotes whether
T20781 7705-7714 VB denotes determine
T20780 7702-7704 TO denotes To
T20779 7699-7700 -RRB- denotes ]
T20778 7697-7699 CD denotes 32
T20777 7696-7697 -LRB- denotes [
T20776 7685-7695 NN denotes activation
T20775 7679-7684 NN denotes STAT1
T20774 7664-7678 JJ denotes IFN-γ-mediated
T20773 7661-7663 IN denotes as
T20772 7656-7660 RB denotes well
T20771 7653-7655 RB denotes as
T20770 7651-7652 -COMMA- denotes ,
T20769 7642-7651 NN denotes responses
T20768 7633-7641 JJ denotes cellular
T20767 7629-7632 CC denotes and
T20766 7618-7628 NN denotes activation
T20765 7612-7617 NN denotes STAT3
T20764 7597-7611 JJ denotes IL-10-mediated
T20763 7589-7596 VB denotes inhibit
T20762 7579-7588 RB denotes partially
T20761 7576-7578 TO denotes to
T20760 7571-7575 JJ denotes able
T20759 7568-7570 VB denotes is
T20758 7562-7567 NN denotes SOCS1
T20757 7560-7561 -COMMA- denotes ,
T20756 7552-7560 NN denotes contrary
T20755 7548-7551 DT denotes the
T20754 7545-7547 IN denotes On
T20753 7542-7543 -RRB- denotes ]
T20752 7539-7542 CD denotes 8,9
T20751 7538-7539 -LRB- denotes [
T20750 7532-7537 NN denotes IL-10
T20749 7528-7531 CC denotes and
T20748 7523-7527 NN denotes IL-6
T20747 7520-7522 IN denotes of
T20746 7513-7519 NN denotes action
T20745 7503-7512 JJ denotes divergent
T20744 7499-7502 DT denotes the
T20743 7488-7498 VB denotes regulating
T20742 7480-7487 RB denotes thereby
T20741 7478-7479 -COMMA- denotes ,
T20740 7473-7478 NN denotes IL-10
T20739 7470-7472 IN denotes by
T20738 7466-7469 RB denotes not
T20737 7462-7465 CC denotes but
T20736 7457-7461 NN denotes IL-6
T20735 7454-7456 IN denotes by
T20734 7446-7453 VB denotes induced
T20733 7435-7445 NN denotes activation
T20732 7429-7434 NN denotes STAT3
T20731 7421-7428 VB denotes inhibit
T20730 7408-7420 RB denotes specifically
T20729 7405-7407 TO denotes to
T20728 7399-7404 VB denotes shown
T20727 7394-7398 VB denotes been
T20726 7385-7393 RB denotes recently
T20725 7381-7384 VB denotes has
T20724 7375-7380 NN denotes SOCS3
T20723 7372-7373 -RRB- denotes ]
T20722 7371-7372 CD denotes 7
T20721 7370-7371 -LRB- denotes [
T20720 7361-7369 NN denotes pathways
T20719 7342-7360 JJ denotes cytokine-signaling
T20718 7336-7341 JJ denotes other
T20717 7327-7335 VB denotes opposing
T20716 7324-7326 IN denotes by
T20715 7313-7323 NN denotes inhibition
T20714 7303-7312 NN denotes crosstalk
T20713 7300-7302 IN denotes in
T20712 7295-7299 NN denotes role
T20711 7289-7294 JJ denotes major
T20710 7287-7288 DT denotes a
T20709 7282-7286 VB denotes play
T20708 7277-7281 RB denotes also
T20707 7273-7276 CC denotes but
T20706 7271-7272 -COMMA- denotes ,
T20705 7261-7271 NN denotes inhibition
T20704 7252-7260 NN denotes feedback
T20703 7243-7251 JJ denotes negative
T20702 7240-7242 IN denotes of
T20701 7230-7239 NN denotes mediators
T20700 7227-7229 IN denotes as
T20699 7223-7226 VB denotes act
T20698 7218-7222 RB denotes only
T20697 7214-7217 RB denotes not
T20696 7209-7213 WDT denotes that
T20695 7207-7208 -RRB- denotes )
T20694 7199-7207 NN denotes proteins
T20693 7193-7198 NN denotes SOCS3
T20692 7189-7192 CC denotes and
T20691 7183-7188 NN denotes SOCS1
T20690 7182-7183 -LRB- denotes (
T20689 7177-7181 NN denotes JAKs
T20688 7174-7176 IN denotes of
T20687 7163-7173 NN denotes inhibitors
T20686 7156-7162 JJ denotes potent
T20685 7152-7155 CD denotes two
T20684 7144-7151 VB denotes induces
T20683 7139-7143 NN denotes IL-6
T20682 7133-7138 NN denotes cells
T20681 7131-7132 NN denotes T
T20680 7126-7130 JJ denotes CD4+
T20679 7123-7125 NN denotes RA
T20678 7120-7122 IN denotes in
T20677 7115-7119 NN denotes mRNA
T20676 7109-7114 NN denotes SOCS1
T20675 7106-7108 IN denotes of
T20674 7095-7105 NN denotes expression
T20673 7090-7094 JJ denotes High
T20907 8425-8430 NN denotes cells
T20906 8423-8424 NN denotes T
T20905 8418-8422 JJ denotes CD4+
T20904 8415-8417 NN denotes RA
T20903 8412-8414 IN denotes in
T20902 8406-8411 NN denotes SOCS1
T20901 8403-8405 IN denotes of
T20900 8393-8402 NN denotes abundance
T20899 8390-8392 DT denotes an
T20898 8387-8389 TO denotes to
T20897 8382-8386 NN denotes part
T20896 8379-8381 IN denotes in
T20895 8373-8378 JJ denotes least
T20894 8370-8372 IN denotes at
T20893 8366-8369 JJ denotes due
T20892 8363-8365 VB denotes be
T20891 8360-8362 TO denotes to
T20890 8352-8359 VB denotes appears
T20889 8342-8351 RB denotes therefore
T20888 8331-8341 NN denotes activation
T20887 8325-8330 NN denotes STAT3
T20886 8311-8324 JJ denotes IL-10-induced
T20885 8301-8310 JJ denotes Defective
T20884 8287-8299 NN denotes significance
T20883 8276-8286 JJ denotes functional
T20882 8272-8275 PRP-DOLLAR- denotes its
T20881 8261-8271 VB denotes supporting
T20880 8259-8260 -COMMA- denotes ,
T20879 8258-8259 -RRB- denotes )
T20878 8256-8258 NN denotes 6b
T20877 8251-8255 NN denotes Fig.
T20876 8250-8251 -LRB- denotes (
T20875 8245-8249 NN denotes IL-6
T20874 8239-8244 NN denotes ng/ml
T20873 8236-8238 CD denotes 10
T20872 8233-8235 IN denotes by
T20871 8222-8232 VB denotes stimulated
T20870 8216-8221 NN denotes cells
T20869 8214-8215 NN denotes T
T20868 8209-8213 JJ denotes CD4+
T20867 8202-8208 JJ denotes normal
T20866 8199-8201 IN denotes in
T20865 8188-8198 NN denotes expression
T20864 8184-8187 DT denotes the
T20863 8179-8183 IN denotes with
T20862 8168-8178 JJ denotes comparable
T20861 8164-8167 VB denotes was
T20860 8158-8163 NN denotes cells
T20859 8156-8157 NN denotes T
T20858 8151-8155 JJ denotes CD4+
T20857 8148-8150 NN denotes RA
T20856 8145-8147 IN denotes in
T20855 8140-8144 NN denotes mRNA
T20854 8134-8139 NN denotes SOCS1
T20853 8131-8133 IN denotes of
T20852 8120-8130 NN denotes expression
T20851 8107-8119 JJ denotes Constitutive
T20850 8104-8105 -RRB- denotes )
T20849 8102-8104 NN denotes 6a
T20848 8097-8101 NN denotes Fig.
T20847 8096-8097 -LRB- denotes (
T20846 8090-8095 NN denotes cells
T20845 8088-8089 NN denotes T
T20844 8083-8087 JJ denotes CD4+
T20843 8075-8082 NN denotes control
T20842 8071-8074 VB denotes did
T20841 8066-8070 IN denotes than
T20840 8054-8065 NN denotes transcripts
T20839 8048-8053 NN denotes SOCS3
T20838 8045-8047 IN denotes of
T20837 8038-8044 NN denotes levels
T20836 8032-8037 JJ denotes lower
T20835 8028-8031 CC denotes but
T20834 8022-8027 NN denotes SOCS1
T20833 8019-8021 IN denotes of
T20832 8012-8018 NN denotes levels
T20831 8005-8011 JJ denotes higher
T20830 7995-8004 VB denotes contained
T20829 7989-7994 NN denotes cells
T20828 7987-7988 NN denotes T
T20827 7982-7986 JJ denotes CD4+
T20826 7979-7981 NN denotes RA
T20825 7975-7978 DT denotes The
T20824 7970-7973 NN denotes PCR
T20823 7960-7969 JJ denotes real-time
T20822 7943-7959 JJ denotes semiquantitative
T20821 7940-7942 IN denotes by
T20820 7931-7939 VB denotes compared
T20819 7926-7930 VB denotes were
T20818 7917-7925 NN denotes controls
T20817 7909-7916 JJ denotes healthy
T20816 7904-7908 IN denotes from
T20815 7900-7903 CC denotes and
T20814 7891-7899 NN denotes patients
T20813 7888-7890 NN denotes RA
T20812 7881-7887 JJ denotes active
T20811 7876-7880 IN denotes from
T20810 7870-7875 NN denotes cells
T20809 7868-7869 NN denotes T
T20808 7863-7867 JJ denotes CD4+
T20807 7860-7862 NN denotes PB
T20806 7857-7859 IN denotes in
T20805 7846-7856 NN denotes expression
T20804 7841-7845 NN denotes mRNA
T20803 7835-7840 NN denotes SOCS3
T18834 6600-6602 CC denotes or
T18833 6591-6599 NN denotes presence
T18832 6587-6590 DT denotes the
T18831 6584-6586 IN denotes in
T18830 6570-6583 NN denotes costimulation
T18829 6565-6569 NN denotes CD28
T18828 6561-6564 CC denotes and
T18827 6557-6560 NN denotes CD3
T18826 6554-6556 IN denotes by
T18825 6543-6553 VB denotes stimulated
T18824 6538-6542 VB denotes were
T18823 6532-6537 NN denotes cells
T18822 6530-6531 NN denotes T
T18821 6525-6529 JJ denotes CD4+
T18820 6518-6524 JJ denotes normal
T18819 6516-6517 -COMMA- denotes ,
T18818 6511-6516 NN denotes hours
T18817 6508-6510 CD denotes 36
T18816 6504-6507 IN denotes for
T18815 6499-6503 NN denotes IL-6
T18814 6493-6498 NN denotes ng/ml
T18813 6490-6492 CD denotes 10
T18812 6482-6489 IN denotes without
T18811 6479-6481 CC denotes or
T18810 6474-6478 IN denotes with
T18809 6460-6473 NN denotes preincubation
T18808 6454-6459 IN denotes After
T18807 6447-6452 NN denotes cells
T18806 6445-6446 NN denotes T
T18805 6440-6444 JJ denotes CD4+
T18804 6437-6439 IN denotes by
T18803 6426-6436 NN denotes production
T18802 6420-6425 NN denotes IFN-γ
T18801 6412-6419 VB denotes inhibit
T18800 6409-6411 TO denotes to
T18799 6403-6408 NN denotes IL-10
T18798 6400-6402 IN denotes of
T18797 6393-6399 NN denotes effect
T18796 6389-6392 DT denotes the
T18795 6380-6388 VB denotes suppress
T18794 6374-6379 MD denotes could
T18793 6369-6373 NN denotes IL-6
T18792 6361-6368 IN denotes whether
T18791 6352-6360 VB denotes examined
T18790 6347-6351 RB denotes next
T18789 6344-6346 PRP denotes We
T18788 6337-6342 NN denotes serum
T18787 6334-6336 NN denotes RA
T18786 6331-6333 IN denotes in
T18785 6323-6330 JJ denotes present
T18784 6320-6322 VB denotes be
T18783 6316-6319 MD denotes may
T18782 6306-6315 NN denotes signaling
T18781 6300-6305 NN denotes STAT1
T18780 6297-6299 IN denotes of
T18779 6286-6296 NN denotes inhibitors
T18778 6281-6285 IN denotes that
T18777 6278-6280 CC denotes or
T18776 6276-6277 -COMMA- denotes ,
T18775 6266-6276 NN denotes activation
T18774 6260-6265 NN denotes STAT3
T18773 6255-6259 IN denotes with
T18772 6246-6254 VB denotes compared
T18771 6243-6245 IN denotes as
T18770 6232-6242 NN denotes activation
T18769 6226-6231 NN denotes STAT1
T18768 6222-6225 IN denotes for
T18767 6213-6221 VB denotes required
T18766 6210-6212 VB denotes be
T18765 6206-6209 MD denotes may
T18764 6201-6205 NN denotes IL-6
T18763 6198-6200 IN denotes of
T18762 6183-6197 NN denotes concentrations
T18761 6176-6182 JJ denotes higher
T18760 6171-6175 RB denotes much
T18759 6166-6170 IN denotes that
T18758 6157-6165 VB denotes suggests
T18757 6151-6156 NN denotes serum
T18756 6148-6150 NN denotes RA
T18755 6145-6147 IN denotes by
T18754 6134-6144 NN denotes activation
T18753 6128-6133 NN denotes STAT1
T18752 6125-6127 IN denotes of
T18751 6120-6124 NN denotes lack
T18750 6116-6119 DT denotes The
T18749 6106-6114 NN denotes patients
T18748 6103-6105 NN denotes RA
T18747 6096-6102 JJ denotes active
T18746 6093-6095 IN denotes of
T18745 6088-6092 NN denotes sera
T18744 6085-6087 IN denotes in
T18743 6075-6084 VB denotes contained
T18742 6068-6074 NN denotes factor
T18741 6051-6067 JJ denotes STAT3-activating
T18740 6042-6050 JJ denotes dominant
T18739 6038-6041 DT denotes the
T18738 6035-6037 VB denotes is
T18737 6030-6034 NN denotes IL-6
T18736 6025-6029 IN denotes that
T18735 6016-6024 VB denotes indicate
T18734 6008-6015 NN denotes results
T18733 6002-6007 DT denotes These
T18732 5999-6000 -RRB- denotes )
T18731 5997-5999 NN denotes 5a
T18730 5992-5996 NN denotes Fig.
T18729 5991-5992 -LRB- denotes (
T18728 5982-5990 NN denotes activity
T18727 5977-5981 NN denotes IL-6
T18726 5974-5976 IN denotes of
T18725 5959-5973 NN denotes neutralization
T18724 5956-5958 IN denotes by
T18723 5946-5955 VB denotes abolished
T18722 5939-5945 RB denotes mostly
T18721 5935-5938 VB denotes was
T18720 5924-5934 NN denotes activation
T18719 5918-5923 NN denotes STAT3
T18718 5913-5917 DT denotes this
T18717 5909-5912 CC denotes and
T18716 5907-5908 -COMMA- denotes ,
T18715 5902-5907 NN denotes STAT1
T18714 5898-5901 RB denotes not
T18713 5894-5897 CC denotes but
T18712 5888-5893 NN denotes STAT3
T18711 5885-5887 IN denotes of
T18710 5869-5884 NN denotes phosphorylation
T18709 5860-5868 NN denotes tyrosine
T18708 5853-5859 VB denotes induce
T18707 5850-5852 TO denotes to
T18706 5845-5849 JJ denotes able
T18705 5841-5844 VB denotes was
T18704 5835-5840 NN denotes serum
T18703 5832-5834 NN denotes RA
T18702 5822-5830 NN denotes analysis
T18701 5817-5821 NN denotes blot
T18700 5809-5816 JJ denotes western
T18699 5806-5808 IN denotes by
T18698 5797-5805 VB denotes examined
T18697 5793-5796 VB denotes was
T18696 5777-5792 NN denotes phosphorylation
T18695 5772-5776 NN denotes STAT
T18694 5768-5771 CC denotes and
T18693 5766-5767 -COMMA- denotes ,
T18692 5758-5766 NN denotes antibody
T18691 5750-5757 NN denotes control
T18690 5747-5749 CC denotes or
T18689 5738-5746 NN denotes antibody
T18688 5728-5737 JJ denotes anti-IL-6
T18687 5715-5727 VB denotes neutralizing
T18686 5711-5714 CC denotes and
T18685 5702-5710 NN denotes patients
T18684 5699-5701 NN denotes RA
T18683 5692-5698 JJ denotes active
T18682 5687-5691 IN denotes from
T18681 5681-5686 NN denotes serum
T18680 5679-5680 NN denotes %
T18679 5677-5679 CD denotes 30
T18678 5666-5676 VB denotes containing
T18677 5659-5665 NN denotes medium
T18676 5651-5658 NN denotes culture
T18675 5646-5650 IN denotes with
T18674 5642-5645 NN denotes min
T18673 5639-5641 CD denotes 20
T18672 5635-5638 IN denotes for
T18671 5625-5634 VB denotes incubated
T18670 5620-5624 RB denotes thus
T18669 5615-5619 VB denotes were
T18668 5609-5614 NN denotes cells
T18667 5607-5608 NN denotes T
T18666 5602-5606 JJ denotes CD4+
T18665 5595-5601 JJ denotes Normal
T18664 5592-5593 -RRB- denotes ]
T18663 5591-5592 CD denotes 4
T18662 5590-5591 -LRB- denotes [
T18661 5577-5589 NN denotes observations
T18660 5568-5576 JJ denotes previous
T18659 5563-5567 IN denotes with
T18658 5553-5562 NN denotes agreement
T18657 5550-5552 IN denotes in
T18656 5548-5549 -COMMA- denotes ,
T18655 5547-5548 -RRB- denotes )
T18654 5542-5547 VB denotes shown
T18653 5538-5541 RB denotes not
T18652 5533-5537 NN denotes data
T18651 5532-5533 -LRB- denotes (
T18650 5526-5531 NN denotes cells
T18649 5524-5525 NN denotes T
T18648 5519-5523 JJ denotes CD4+
T18647 5512-5518 JJ denotes normal
T18646 5509-5511 IN denotes in
T18645 5504-5508 NN denotes IL-6
T18644 5501-5503 IN denotes by
T18643 5491-5500 VB denotes activated
T18642 5487-5490 VB denotes was
T18641 5471-5486 NN denotes phosphorylation
T18640 5465-5470 NN denotes STAT3
T18639 5461-5464 CC denotes and
T18638 5455-5460 NN denotes STAT1
T18637 5450-5454 CC denotes Both
T18636 5446-5448 NN denotes RA
T18635 5439-5445 JJ denotes active
T18634 5436-5438 IN denotes in
T18633 5425-5435 NN denotes inhibition
T18632 5419-5424 NN denotes IL-10
T18631 5416-5418 TO denotes to
T18630 5405-5415 NN denotes resistance
T18629 5401-5404 CC denotes and
T18628 5390-5400 NN denotes activation
T18627 5384-5389 NN denotes STAT3
T18626 5374-5383 JJ denotes sustained
T18625 5368-5373 PRP-DOLLAR- denotes their
T18624 5364-5367 IN denotes for
T18623 5352-5363 JJ denotes responsible
T18622 5348-5351 VB denotes was
T18621 5336-5347 NN denotes circulation
T18620 5330-5335 NN denotes blood
T18619 5326-5329 DT denotes the
T18595 5208-5216 VB denotes detected
T18594 5197-5207 RB denotes frequently
T18593 5195-5196 -COMMA- denotes ,
T18592 5187-5195 NN denotes patients
T18591 5184-5186 NN denotes RA
T18590 5177-5183 JJ denotes active
T18589 5174-5176 IN denotes of
T18588 5169-5173 NN denotes sera
T18587 5166-5168 IN denotes in
T18586 5157-5165 JJ denotes abundant
T18585 5152-5156 RB denotes also
T18584 5149-5151 VB denotes is
T18583 5144-5148 NN denotes IL-6
T18582 5138-5143 IN denotes Since
T18581 5135-5136 -RRB- denotes ]
T18580 5133-5135 CD denotes 31
T18579 5132-5133 -LRB- denotes [
T18578 5126-5131 NN denotes cells
T18577 5114-5125 JJ denotes mononuclear
T18576 5111-5113 IN denotes in
T18575 5105-5110 NN denotes STAT3
T18574 5102-5104 IN denotes of
T18573 5091-5101 NN denotes activation
T18572 5078-5090 JJ denotes constitutive
T18571 5070-5077 VB denotes induces
T18570 5065-5069 WDT denotes that
T18569 5059-5064 NN denotes fluid
T18568 5050-5058 JJ denotes synovial
T18567 5047-5049 NN denotes RA
T18566 5044-5046 IN denotes in
T18565 5037-5043 NN denotes factor
T18564 5031-5036 JJ denotes major
T18563 5027-5030 DT denotes the
T18562 5024-5026 VB denotes is
T18561 5019-5023 NN denotes IL-6
T18560 5014-5018 IN denotes that
T18559 5001-5013 VB denotes demonstrated
T18558 4996-5000 VB denotes have
T18557 4988-4995 NN denotes studies
T18556 4979-4987 JJ denotes previous
T18555 4975-4978 CC denotes but
T18554 4973-4974 -COMMA- denotes ,
T18553 4972-4973 -RRB- denotes ]
T18552 4971-4972 CD denotes 4
T18551 4970-4971 -LRB- denotes [
T18550 4964-4969 NN denotes IL-10
T18549 4961-4963 TO denotes to
T18548 4952-4960 NN denotes addition
T18547 4949-4951 IN denotes in
T18546 4947-4948 -COMMA- denotes ,
T18545 4941-4947 NN denotes factor
T18544 4934-4940 NN denotes growth
T18543 4924-4933 JJ denotes epidermal
T18542 4920-4923 CC denotes and
T18541 4918-4919 -COMMA- denotes ,
T18540 4912-4918 NN denotes factor
T18539 4905-4911 NN denotes growth
T18538 4888-4904 JJ denotes platelet-derived
T18537 4886-4887 -COMMA- denotes ,
T18536 4885-4886 -RRB- denotes )
T18535 4884-4885 NN denotes M
T18534 4873-4883 NN denotes oncostatin
T18533 4869-4872 CC denotes and
T18532 4867-4868 -COMMA- denotes ,
T18531 4861-4867 NN denotes factor
T18530 4850-4860 JJ denotes inhibitory
T18529 4841-4849 NN denotes leukemia
T18528 4839-4840 -COMMA- denotes ,
T18527 4834-4839 NN denotes IL-11
T18526 4832-4833 -COMMA- denotes ,
T18525 4828-4832 NN denotes IL-6
T18524 4827-4828 -LRB- denotes (
T18523 4817-4826 NN denotes cytokines
T18522 4814-4816 IN denotes of
T18521 4807-4813 NN denotes family
T18520 4802-4806 NN denotes IL-6
T18519 4798-4801 DT denotes the
T18518 4795-4797 IN denotes as
T18517 4790-4794 JJ denotes such
T18516 4782-4789 NN denotes factors
T18515 4775-4781 NN denotes growth
T18514 4771-4774 CC denotes and
T18513 4761-4770 NN denotes cytokines
T18512 4756-4760 JJ denotes many
T18511 4753-4755 IN denotes by
T18510 4743-4752 VB denotes activated
T18509 4740-4742 VB denotes is
T18508 4734-4739 NN denotes STAT3
T18507 4728-4733 NN denotes cells
T18506 4726-4727 NN denotes T
T18505 4721-4725 JJ denotes CD4+
T18504 4714-4720 JJ denotes normal
T18503 4711-4713 IN denotes in
T18502 4704-4710 NN denotes effect
T18501 4698-4703 NN denotes IL-10
T18500 4695-4697 IN denotes of
T18499 4684-4694 NN denotes inhibition
T18498 4680-4683 CC denotes and
T18497 4664-4679 NN denotes phosphorylation
T18496 4658-4663 NN denotes STAT3
T18495 4644-4657 JJ denotes IL-6-mediated
T18915 7080-7081 NN denotes T
T18914 7075-7079 JJ denotes CD4+
T18913 7072-7074 NN denotes RA
T18912 7069-7071 IN denotes in
T18911 7063-7068 NN denotes IL-10
T18910 7060-7062 IN denotes of
T18909 7053-7059 NN denotes effect
T18908 7042-7052 JJ denotes inhibitory
T18907 7038-7041 DT denotes the
T18906 7035-7037 TO denotes to
T18905 7024-7034 NN denotes resistance
T18904 7020-7023 DT denotes the
T18903 7016-7019 CC denotes and
T18902 7005-7015 NN denotes activation
T18901 6999-7004 NN denotes STAT3
T18900 6996-6998 IN denotes of
T18899 6986-6995 NN denotes induction
T18898 6982-6985 DT denotes the
T18897 6977-6981 CC denotes both
T18896 6974-6976 IN denotes in
T18895 6969-6973 NN denotes role
T18894 6967-6968 DT denotes a
T18893 6962-6966 VB denotes have
T18892 6958-6961 MD denotes may
T18891 6953-6957 NN denotes IL-6
T18890 6947-6952 NN denotes serum
T18889 6944-6946 TO denotes to
T18888 6935-6943 NN denotes exposure
T18887 6924-6934 JJ denotes persistent
T18886 6919-6923 IN denotes that
T18885 6911-6918 VB denotes suggest
T18884 6902-6910 NN denotes findings
T18883 6896-6901 DT denotes these
T18882 6894-6895 -COMMA- denotes ,
T18881 6886-6894 RB denotes together
T18880 6880-6885 VB denotes Taken
T18879 6873-6878 NN denotes IL-10
T18878 6870-6872 TO denotes to
T18877 6855-6869 NN denotes responsiveness
T18876 6848-6854 NN denotes T-cell
T18875 6839-6847 VB denotes modulate
T18874 6833-6838 MD denotes could
T18873 6828-6832 NN denotes IL-6
T18872 6825-6827 IN denotes of
T18871 6810-6824 NN denotes concentrations
T18870 6805-6809 JJ denotes high
T18869 6800-6804 IN denotes that
T18868 6789-6799 VB denotes indicating
T18867 6787-6788 -COMMA- denotes ,
T18866 6786-6787 -RRB- denotes )
T18865 6784-6786 NN denotes 5b
T18864 6779-6783 NN denotes Fig.
T18863 6778-6779 -LRB- denotes (
T18862 6767-6777 NN denotes production
T18861 6761-6766 NN denotes IFN-γ
T18860 6758-6760 IN denotes of
T18859 6747-6757 NN denotes inhibition
T18858 6732-6746 JJ denotes IL-10-mediated
T18857 6724-6731 VB denotes reduced
T18856 6718-6723 NN denotes cells
T18855 6711-6717 JJ denotes normal
T18854 6708-6710 IN denotes of
T18853 6695-6707 NN denotes pretreatment
T18852 6690-6694 NN denotes IL-6
T18851 6683-6688 NN denotes ELISA
T18850 6680-6682 IN denotes by
T18849 6671-6679 VB denotes measured
T18848 6667-6670 VB denotes was
T18847 6656-6666 NN denotes production
T18846 6650-6655 NN denotes IFN-γ
T18845 6646-6649 DT denotes the
T18844 6642-6645 CC denotes and
T18843 6640-6641 -COMMA- denotes ,
T18842 6635-6640 NN denotes hours
T18841 6632-6634 CD denotes 36
T18840 6628-6631 IN denotes for
T18839 6622-6627 NN denotes IL-10
T18838 6616-6621 NN denotes ng/ml
T18837 6614-6615 CD denotes 1
T18836 6611-6613 IN denotes of
T18835 6603-6610 NN denotes absence
T18618 5323-5325 IN denotes in
T18617 5318-5322 NN denotes IL-6
T18616 5315-5317 IN denotes of
T18615 5300-5314 NN denotes concentrations
T18614 5295-5299 JJ denotes high
T18613 5292-5294 TO denotes to
T18612 5286-5291 NN denotes cells
T18611 5284-5285 NN denotes T
T18610 5279-5283 JJ denotes CD4+
T18609 5276-5278 IN denotes of
T18608 5267-5275 NN denotes exposure
T18607 5256-5266 JJ denotes persistent
T18606 5248-5255 IN denotes whether
T18605 5239-5247 VB denotes examined
T18604 5236-5238 PRP denotes we
T18603 5234-5235 -COMMA- denotes ,
T18602 5233-5234 -RRB- denotes ]
T18601 5231-5233 CD denotes 27
T18600 5230-5231 -LRB- denotes [
T18599 5224-5229 NN denotes ng/ml
T18598 5222-5223 CD denotes 1
T18597 5220-5221 SYM denotes >
T18596 5217-5219 IN denotes at
T16427 4626-4641 NN denotes phosphorylation
T16426 4620-4625 NN denotes STAT3
T16425 4610-4619 JJ denotes sustained
T16424 4605-4609 IN denotes with
T16423 4593-4604 NN denotes association
T16422 4590-4592 IN denotes in
T16421 4588-4589 -COMMA- denotes ,
T16420 4586-4588 NN denotes RA
T16419 4579-4585 JJ denotes active
T16418 4576-4578 IN denotes in
T16417 4565-4575 VB denotes diminished
T16416 4562-4564 VB denotes be
T16415 4558-4561 MD denotes may
T16414 4547-4557 NN denotes activation
T16413 4541-4546 NN denotes STAT3
T16412 4527-4540 JJ denotes IL-10-induced
T16411 4523-4526 CC denotes and
T16410 4521-4522 -COMMA- denotes ,
T16409 4516-4521 NN denotes cells
T16408 4514-4515 NN denotes T
T16407 4509-4513 JJ denotes CD4+
T16406 4506-4508 IN denotes in
T16405 4501-4505 NN denotes STAT
T16404 4485-4500 JJ denotes IL-10-activated
T16403 4479-4484 JJ denotes major
T16402 4475-4478 DT denotes the
T16401 4472-4474 VB denotes is
T16400 4466-4471 NN denotes STAT3
T16399 4461-4465 IN denotes that
T16398 4452-4460 VB denotes indicate
T16397 4444-4451 NN denotes results
T16396 4438-4443 DT denotes These
T16395 4435-4436 -RRB- denotes )
T16394 4433-4435 NN denotes 4a
T16393 4428-4432 NN denotes Fig.
T16392 4427-4428 -LRB- denotes (
T16391 4421-4426 NN denotes cells
T16390 4419-4420 NN denotes T
T16389 4414-4418 JJ denotes CD4+
T16388 4407-4413 JJ denotes normal
T16387 4404-4406 CC denotes or
T16386 4398-4403 NN denotes cells
T16385 4396-4397 NN denotes T
T16384 4391-4395 JJ denotes CD4+
T16383 4388-4390 NN denotes RA
T16382 4381-4387 CC denotes either
T16381 4378-4380 IN denotes in
T16380 4369-4377 VB denotes detected
T16379 4365-4368 RB denotes not
T16378 4361-4364 VB denotes was
T16377 4345-4360 NN denotes phosphorylation
T16376 4339-4344 NN denotes STAT1
T16375 4325-4338 JJ denotes IL-10-induced
T16374 4323-4324 -COMMA- denotes ,
T16373 4319-4323 NN denotes hand
T16372 4313-4318 JJ denotes other
T16371 4309-4312 DT denotes the
T16370 4306-4308 IN denotes On
T16369 4303-4304 -RRB- denotes )
T16368 4301-4303 NN denotes 4c
T16367 4296-4300 NN denotes Fig.
T16366 4295-4296 -LRB- denotes (
T16365 4289-4294 NN denotes cells
T16364 4287-4288 NN denotes T
T16363 4282-4286 JJ denotes CD4+
T16362 4279-4281 JJ denotes ST
T16361 4276-4278 NN denotes RA
T16360 4273-4275 IN denotes in
T16359 4267-4272 VB denotes found
T16358 4262-4266 VB denotes were
T16357 4246-4261 NN denotes phosphorylation
T16356 4240-4245 NN denotes STAT3
T16355 4226-4239 JJ denotes IL-10-induced
T16354 4216-4225 JJ denotes defective
T16353 4212-4215 CC denotes and
T16352 4196-4211 NN denotes phosphorylation
T16351 4190-4195 NN denotes STAT3
T16350 4180-4189 JJ denotes sustained
T16349 4175-4179 CC denotes Both
T16348 4168-4173 NN denotes IL-10
T16347 4162-4167 NN denotes ng/ml
T16346 4159-4161 CD denotes 10
T16345 4156-4158 IN denotes as
T16344 4151-4155 JJ denotes much
T16343 4148-4150 RB denotes as
T16342 4145-4147 IN denotes by
T16341 4135-4144 VB denotes activated
T16289 3835-3838 VB denotes was
T16288 3819-3834 NN denotes phosphorylation
T16287 3813-3818 NN denotes STAT3
T16286 3803-3811 NN denotes blotting
T16285 3795-3802 JJ denotes western
T16284 3789-3794 VB denotes using
T16283 3780-3788 VB denotes examined
T16282 3776-3779 VB denotes was
T16281 3767-3775 NN denotes controls
T16280 3759-3766 JJ denotes healthy
T16279 3754-3758 IN denotes from
T16278 3750-3753 CC denotes and
T16277 3741-3749 NN denotes patients
T16276 3738-3740 NN denotes RA
T16275 3731-3737 JJ denotes active
T16274 3726-3730 IN denotes from
T16273 3720-3725 NN denotes cells
T16272 3718-3719 NN denotes T
T16271 3713-3717 JJ denotes CD4+
T16270 3710-3712 NN denotes PB
T16269 3707-3709 IN denotes in
T16268 3701-3706 NN denotes IL-10
T16267 3698-3700 IN denotes by
T16266 3682-3697 NN denotes phosphorylation
T16265 3676-3681 NN denotes STAT3
T16264 3672-3675 CC denotes and
T16263 3666-3671 NN denotes STAT1
T16262 3663-3665 IN denotes of
T16261 3653-3662 NN denotes induction
T16260 3649-3652 DT denotes The
T16259 3646-3647 -RRB- denotes ]
T16258 3644-3646 CD denotes 30
T16257 3643-3644 -LRB- denotes [
T16256 3628-3642 NN denotes overexpression
T16255 3622-3627 NN denotes STAT3
T16254 3604-3621 JJ denotes dominant-negative
T16253 3601-3603 IN denotes of
T16252 3593-3600 NN denotes studies
T16251 3590-3592 IN denotes by
T16250 3578-3589 NN denotes macrophages
T16249 3572-3577 JJ denotes human
T16248 3569-3571 IN denotes in
T16247 3559-3568 VB denotes confirmed
T16246 3554-3558 VB denotes been
T16245 3545-3553 RB denotes recently
T16244 3541-3544 VB denotes has
T16243 3535-3540 WDT denotes which
T16242 3533-3534 -COMMA- denotes ,
T16241 3532-3533 -RRB- denotes ]
T16240 3531-3532 CD denotes 5
T16239 3530-3531 -LRB- denotes [
T16238 3520-3529 NN denotes responses
T16237 3502-3519 JJ denotes anti-inflammatory
T16236 3487-3501 JJ denotes IL-10-mediated
T16235 3484-3486 IN denotes in
T16234 3479-3483 NN denotes role
T16233 3470-3478 JJ denotes dominant
T16232 3468-3469 DT denotes a
T16231 3462-3467 VB denotes plays
T16230 3456-3461 NN denotes STAT3
T16229 3451-3455 IN denotes that
T16228 3438-3450 VB denotes demonstrated
T16227 3433-3437 NN denotes mice
T16226 3417-3432 JJ denotes STAT3-deficient
T16225 3397-3416 JJ denotes Macrophage-specific
T16224 3394-3395 -RRB- denotes ]
T16223 3393-3394 CD denotes 3
T16222 3392-3393 -LRB- denotes [
T16221 3386-3391 NN denotes STAT3
T16220 3382-3385 CC denotes and
T16219 3376-3381 NN denotes STAT1
T16218 3368-3375 NN denotes factors
T16217 3354-3367 NN denotes transcription
T16216 3347-3353 JJ denotes latent
T16215 3343-3346 DT denotes the
T16214 3340-3342 IN denotes of
T16213 3329-3339 NN denotes activation
T16212 3325-3328 CC denotes and
T16211 3309-3324 NN denotes phosphorylation
T16210 3300-3308 NN denotes tyrosine
T16209 3292-3299 VB denotes induces
T16208 3286-3291 NN denotes IL-10
T16207 3281-3285 IN denotes with
T16206 3274-3280 NN denotes IL-10R
T16205 3271-3273 IN denotes of
T16204 3259-3270 NN denotes interaction
T16203 3255-3258 DT denotes The
T16202 3249-3254 NN denotes cells
T16201 3247-3248 NN denotes T
T16200 3242-3246 JJ denotes CD4+
T16199 3239-3241 NN denotes RA
T16198 3236-3238 IN denotes in
T16197 3220-3235 NN denotes phosphorylation
T16196 3214-3219 NN denotes STAT3
T16195 3199-3213 JJ denotes IL-10-mediated
T16194 3189-3198 JJ denotes Defective
T16340 4130-4134 WRB denotes when
T16339 4125-4129 RB denotes only
T16338 4115-4124 VB denotes augmented
T16337 4111-4114 VB denotes was
T16336 4095-4110 NN denotes phosphorylation
T16335 4089-4094 NN denotes STAT3
T16334 4082-4087 NN denotes hours
T16333 4080-4081 CD denotes 6
T16332 4077-4079 TO denotes to
T16331 4074-4076 IN denotes up
T16330 4070-4073 IN denotes for
T16329 4059-4069 JJ denotes detectable
T16328 4055-4058 VB denotes was
T16327 4039-4054 NN denotes phosphorylation
T16326 4033-4038 NN denotes STAT3
T16325 4028-4032 DT denotes this
T16324 4024-4027 CC denotes and
T16323 4015-4023 NN denotes patients
T16322 4012-4014 NN denotes RA
T16321 4007-4011 IN denotes from
T16320 4001-4006 NN denotes cells
T16319 3996-4000 JJ denotes CD4+
T16318 3993-3995 NN denotes PB
T16317 3984-3992 VB denotes isolated
T16316 3976-3983 RB denotes freshly
T16315 3973-3975 IN denotes in
T16314 3958-3972 VB denotes phosphorylated
T16313 3954-3957 VB denotes was
T16312 3948-3953 NN denotes STAT3
T16311 3946-3947 -COMMA- denotes ,
T16310 3938-3946 NN denotes contrast
T16309 3935-3937 IN denotes In
T16308 3932-3933 -RRB- denotes )
T16307 3930-3932 NN denotes 4b
T16306 3929-3930 -COMMA- denotes ,
T16305 3927-3929 NN denotes 4a
T16304 3922-3926 NN denotes Fig.
T16303 3921-3922 -LRB- denotes (
T16302 3915-3920 NN denotes cells
T16301 3913-3914 NN denotes T
T16300 3908-3912 JJ denotes CD4+
T16299 3901-3907 JJ denotes normal
T16298 3898-3900 IN denotes in
T16297 3894-3897 NN denotes min
T16296 3891-3893 CD denotes 20
T16295 3887-3890 IN denotes for
T16294 3876-3886 NN denotes activation
T16293 3870-3875 NN denotes IL-10
T16292 3864-3869 IN denotes after
T16291 3856-3863 VB denotes induced
T16290 3839-3855 RB denotes dose-dependently
T14999 3184-3186 NN denotes RA
T14998 3177-3183 JJ denotes active
T14997 3174-3176 IN denotes of
T14996 3168-3173 NN denotes cells
T14995 3166-3167 NN denotes T
T14994 3161-3165 JJ denotes CD4+
T14993 3158-3160 IN denotes in
T14992 3149-3157 VB denotes impaired
T14991 3146-3148 VB denotes be
T14990 3142-3145 MD denotes may
T14989 3136-3141 NN denotes IL-10
T14988 3133-3135 IN denotes of
T14987 3125-3132 NN denotes pathway
T14986 3112-3124 NN denotes transduction
T14985 3105-3111 NN denotes signal
T14984 3091-3104 JJ denotes intracellular
T14983 3087-3090 DT denotes the
T14982 3082-3086 IN denotes that
T14981 3074-3081 VB denotes suggest
T14980 3066-3073 NN denotes results
T14979 3060-3065 DT denotes These
T14978 3050-3058 NN denotes controls
T14977 3042-3049 JJ denotes healthy
T14976 3039-3041 IN denotes in
T14975 3034-3038 IN denotes with
T14974 3025-3033 VB denotes compared
T14973 3016-3024 NN denotes patients
T14972 3013-3015 NN denotes RA
T14971 3010-3012 IN denotes in
T14970 3000-3009 VB denotes increased
T14969 2986-2999 RB denotes significantly
T14968 2982-2985 VB denotes was
T14967 2976-2981 NN denotes cells
T14966 2974-2975 NN denotes T
T14965 2969-2973 JJ denotes CD4+
T14964 2966-2968 IN denotes on
T14963 2955-2965 NN denotes expression
T14962 2947-2954 NN denotes IL-10R1
T14961 2944-2946 IN denotes of
T14960 2934-2943 NN denotes intensity
T14959 2930-2933 DT denotes the
T14958 2928-2929 -COMMA- denotes ,
T14957 2926-2928 NN denotes 3b
T14956 2925-2926 -COMMA- denotes ,
T14955 2923-2925 NN denotes 3a
T14954 2918-2922 NNP denotes Fig.
T14953 2915-2917 IN denotes in
T14952 2909-2914 VB denotes shown
T14951 2906-2908 IN denotes As
T14950 2896-2904 NN denotes analysis
T14949 2885-2895 JJ denotes cytometric
T14948 2880-2884 NN denotes flow
T14947 2877-2879 IN denotes by
T14946 2866-2876 VB denotes determined
T14945 2862-2865 VB denotes was
T14944 2853-2861 NN denotes controls
T14943 2845-2852 JJ denotes healthy
T14942 2840-2844 IN denotes from
T14941 2836-2839 CC denotes and
T14940 2827-2835 NN denotes patients
T14939 2824-2826 NN denotes RA
T14938 2817-2823 JJ denotes active
T14937 2812-2816 IN denotes from
T14936 2806-2811 NN denotes cells
T14935 2804-2805 NN denotes T
T14934 2799-2803 JJ denotes CD4+
T14933 2796-2798 NN denotes PB
T14932 2793-2795 IN denotes on
T14931 2785-2792 NN denotes IL-10R1
T14930 2782-2784 IN denotes of
T14929 2771-2781 NN denotes expression
T14928 2763-2770 NN denotes surface
T14927 2758-2762 NN denotes cell
T14926 2754-2757 DT denotes the
T14925 2752-2753 -COMMA- denotes ,
T14924 2742-2752 NN denotes expression
T14923 2733-2741 NN denotes receptor
T14922 2725-2732 VB denotes limited
T14921 2722-2724 TO denotes to
T14920 2718-2721 JJ denotes due
T14919 2714-2717 VB denotes was
T14918 2708-2713 NN denotes cells
T14917 2706-2707 NN denotes T
T14916 2701-2705 JJ denotes CD4+
T14915 2698-2700 NN denotes RA
T14914 2695-2697 IN denotes in
T14913 2684-2694 NN denotes inhibition
T14912 2678-2683 NN denotes IL-10
T14911 2675-2677 TO denotes to
T14910 2664-2674 NN denotes resistance
T14909 2660-2663 DT denotes the
T14908 2652-2659 IN denotes whether
T14907 2644-2651 VB denotes examine
T14906 2641-2643 TO denotes To
T14905 2638-2639 -RRB- denotes ]
T14904 2636-2638 CD denotes 29
T14903 2635-2636 -LRB- denotes [
T14902 2629-2634 NN denotes IL-10
T14901 2626-2628 TO denotes to
T14900 2616-2625 NN denotes responses
T14899 2607-2615 JJ denotes cellular
T14898 2604-2606 IN denotes in
T14897 2599-2603 NN denotes role
T14896 2590-2598 JJ denotes critical
T14895 2588-2589 DT denotes a
T14894 2582-2587 VB denotes plays
T14893 2571-2581 NN denotes expression
T14892 2563-2570 NN denotes IL-10R1
T14891 2560-2561 -RRB- denotes ]
T14890 2559-2560 CD denotes 1
T14889 2558-2559 -LRB- denotes [
T14888 2551-2557 NN denotes IL-10R
T14887 2549-2550 CD denotes 2
T14886 2544-2548 NN denotes type
T14885 2534-2543 NN denotes component
T14884 2524-2533 JJ denotes accessory
T14883 2520-2523 DT denotes the
T14882 2516-2519 CC denotes and
T14881 2508-2515 NN denotes IL-10R1
T14880 2498-2507 NN denotes component
T14879 2483-2497 JJ denotes ligand-binding
T14878 2475-2482 JJ denotes primary
T14877 2471-2474 DT denotes the
T14876 2469-2470 -COMMA- denotes ,
T14875 2461-2469 NN denotes subunits
T14874 2457-2460 CD denotes two
T14873 2454-2456 IN denotes of
T14872 2445-2453 VB denotes consists
T14871 2439-2444 NN denotes IL-10
T14870 2436-2438 IN denotes of
T14869 2428-2435 NN denotes complex
T14868 2419-2427 NN denotes receptor
T14867 2408-2418 JJ denotes functional
T14866 2404-2407 DT denotes The
T14865 2398-2403 NN denotes cells
T14864 2396-2397 NN denotes T
T14863 2391-2395 JJ denotes CD4+
T14862 2388-2390 NN denotes RA
T14861 2385-2387 IN denotes on
T14860 2377-2384 NN denotes IL-10R1
T14859 2369-2376 NN denotes surface
T14858 2364-2368 NN denotes cell
T14857 2361-2363 IN denotes of
T14856 2350-2360 NN denotes expression
T14855 2340-2349 VB denotes Increased
T13584 2332-2337 NN denotes phase
T13583 2325-2331 JJ denotes active
T13582 2321-2324 DT denotes the
T13581 2314-2320 IN denotes during
T13580 2308-2313 NN denotes IL-10
T13579 2305-2307 IN denotes of
T13578 2298-2304 NN denotes effect
T13577 2281-2297 JJ denotes immunoregulatory
T13576 2277-2280 DT denotes the
T13575 2274-2276 TO denotes to
T13574 2262-2273 JJ denotes susceptible
T13573 2257-2261 RB denotes less
T13572 2250-2256 VB denotes become
T13571 2244-2249 NN denotes cells
T13570 2242-2243 NN denotes T
T13569 2237-2241 JJ denotes CD4+
T13568 2234-2236 NN denotes RA
T13567 2229-2233 IN denotes that
T13566 2220-2228 VB denotes indicate
T13565 2212-2219 NN denotes results
T13564 2206-2211 DT denotes these
T13563 2204-2205 -COMMA- denotes ,
T13562 2196-2204 RB denotes together
T13561 2190-2195 VB denotes Taken
T13560 2187-2188 -RRB- denotes )
T13559 2183-2187 CD denotes 0.05
T13558 2181-2182 SYM denotes <
T13557 2179-2180 NN denotes P
T13556 2177-2178 -COLON- denotes ;
T13555 2176-2177 NN denotes %
T13554 2172-2176 CD denotes 13.7
T13553 2170-2171 SYM denotes ±
T13552 2165-2169 CD denotes 61.1
T13551 2164-2165 -LRB- denotes (
T13550 2155-2163 NN denotes controls
T13549 2147-2154 JJ denotes healthy
T13548 2144-2146 IN denotes in
T13547 2136-2143 VB denotes reduced
T13546 2122-2135 RB denotes significantly
T13545 2118-2121 VB denotes was
T13544 2115-2117 PRP denotes it
T13543 2109-2114 IN denotes while
T13542 2107-2108 -COMMA- denotes ,
T13541 2106-2107 -RRB- denotes )
T13540 2105-2106 NN denotes %
T13539 2101-2105 CD denotes 13.8
T13538 2099-2100 -COLON- denotes ±
T13537 2094-2098 CD denotes -2.1
T13536 2092-2093 -COMMA- denotes ,
T13535 2084-2092 NN denotes decrease
T13534 2073-2083 NN denotes percentage
T13533 2072-2073 -LRB- denotes (
T13532 2063-2071 NN denotes patients
T13531 2060-2062 NN denotes RA
T13530 2057-2059 IN denotes in
T13529 2051-2056 NN denotes IL-10
T13528 2045-2050 NN denotes ng/ml
T13527 2043-2044 CD denotes 1
T13526 2040-2042 IN denotes by
T13525 2031-2039 VB denotes affected
T13524 2027-2030 RB denotes not
T13523 2023-2026 VB denotes was
T13522 2012-2022 NN denotes production
T13521 2007-2011 NN denotes IL-2
T13520 2005-2006 -COMMA- denotes ,
T13519 1996-2005 RB denotes Similarly
T13518 1986-1994 NN denotes controls
T13517 1978-1985 JJ denotes healthy
T13516 1975-1977 IN denotes in
T13515 1971-1974 CC denotes and
T13514 1962-1970 NN denotes patients
T13513 1959-1961 NN denotes RA
T13512 1952-1958 JJ denotes active
T13511 1949-1951 IN denotes in
T13510 1943-1948 NN denotes IL-10
T13509 1940-1942 IN denotes of
T13508 1931-1939 NN denotes presence
T13507 1927-1930 DT denotes the
T13506 1924-1926 IN denotes in
T13505 1910-1923 NN denotes costimulation
T13504 1905-1909 NN denotes CD28
T13503 1901-1904 CC denotes and
T13502 1897-1900 NN denotes CD3
T13501 1891-1896 IN denotes after
T13500 1885-1890 NN denotes cells
T13499 1883-1884 NN denotes T
T13498 1878-1882 JJ denotes CD4+
T13432 1598-1599 -COMMA- denotes ,
T13431 1596-1598 NN denotes RA
T13430 1589-1595 JJ denotes active
T13429 1587-1588 -COLON- denotes :
T13428 1579-1587 NN denotes decrease
T13427 1568-1578 NN denotes percentage
T13426 1567-1568 -LRB- denotes (
T13425 1558-1566 NN denotes controls
T13424 1550-1557 JJ denotes healthy
T13423 1546-1549 CC denotes and
T13422 1540-1545 NN denotes group
T13421 1537-1539 NN denotes RA
T13420 1528-1536 JJ denotes inactive
T13419 1524-1527 DT denotes the
T13418 1519-1523 IN denotes with
T13417 1510-1518 VB denotes compared
T13416 1507-1509 IN denotes as
T13415 1501-1506 NN denotes group
T13414 1498-1500 NN denotes RA
T13413 1491-1497 JJ denotes active
T13412 1487-1490 DT denotes the
T13411 1484-1486 IN denotes in
T13410 1476-1483 VB denotes limited
T13409 1462-1475 RB denotes significantly
T13408 1458-1461 VB denotes was
T13407 1447-1457 NN denotes production
T13406 1441-1446 NN denotes IFN-γ
T13405 1438-1440 IN denotes on
T13404 1432-1437 NN denotes IL-10
T13403 1429-1431 IN denotes of
T13402 1422-1428 NN denotes effect
T13401 1411-1421 JJ denotes inhibitory
T13400 1407-1410 DT denotes the
T13399 1403-1406 CC denotes but
T13398 1401-1402 -COMMA- denotes ,
T13397 1400-1401 -RRB- denotes )
T13396 1398-1400 NN denotes 2a
T13395 1393-1397 NNP denotes Fig.
T13394 1392-1393 -LRB- denotes (
T13393 1385-1391 NN denotes groups
T13392 1379-1384 CD denotes three
T13391 1373-1378 DT denotes these
T13390 1367-1372 IN denotes among
T13389 1361-1366 NN denotes IL-10
T13388 1353-1360 IN denotes without
T13387 1342-1352 NN denotes production
T13386 1336-1341 NN denotes IFN-γ
T13385 1333-1335 IN denotes in
T13384 1321-1332 NN denotes differences
T13383 1309-1320 JJ denotes significant
T13382 1295-1308 RB denotes statistically
T13381 1292-1294 DT denotes no
T13380 1287-1291 VB denotes were
T13379 1281-1286 EX denotes There
T13378 1271-1279 NN denotes controls
T13377 1263-1270 JJ denotes healthy
T13376 1260-1262 IN denotes in
T13375 1256-1259 CC denotes and
T13374 1254-1255 -RRB- denotes ]
T13373 1252-1254 CD denotes 26
T13372 1251-1252 -LRB- denotes [
T13371 1249-1250 -RRB- denotes )
T13370 1245-1249 NN denotes mg/l
T13369 1242-1244 CD denotes 10
T13368 1240-1241 SYM denotes <
T13367 1234-1239 NN denotes level
T13366 1230-1233 NN denotes CRP
T13365 1228-1229 -COMMA- denotes ,
T13364 1219-1228 NN denotes remission
T13363 1216-1218 IN denotes in
T13362 1215-1216 -LRB- denotes (
T13361 1207-1214 NN denotes disease
T13360 1198-1206 JJ denotes inactive
T13359 1194-1197 CC denotes and
T13358 1192-1193 -RRB- denotes )
T13357 1188-1192 NN denotes mg/l
T13356 1185-1187 CD denotes 10
T13355 1183-1184 NN denotes ≥
T13354 1177-1182 NN denotes level
T13353 1173-1176 NN denotes CRP
T13352 1171-1172 -COMMA- denotes ,
T13351 1165-1171 NN denotes joints
T13350 1152-1164 JJ denotes inflammatory
T13349 1143-1151 JJ denotes multiple
T13348 1142-1143 -LRB- denotes (
T13347 1134-1141 NN denotes disease
T13346 1127-1133 JJ denotes active
T13345 1122-1126 IN denotes with
T13344 1113-1121 NN denotes patients
T13343 1110-1112 NN denotes RA
T13342 1107-1109 IN denotes in
T13341 1101-1106 NN denotes IL-10
T13340 1095-1100 NN denotes ng/ml
T13339 1093-1094 CD denotes 1
T13338 1090-1092 IN denotes of
T13337 1081-1089 NN denotes presence
T13336 1077-1080 DT denotes the
T13335 1074-1076 IN denotes in
T13334 1060-1073 NN denotes costimulation
T13333 1055-1059 NN denotes CD28
T13332 1051-1054 CC denotes and
T13331 1047-1050 NN denotes CD3
T13330 1041-1046 IN denotes after
T13329 1035-1040 NN denotes cells
T13328 1033-1034 NN denotes T
T13327 1028-1032 JJ denotes CD4+
T13326 1025-1027 IN denotes by
T13325 1014-1024 NN denotes production
T13324 1008-1013 NN denotes IFN-γ
T13323 1005-1007 IN denotes of
T13322 998-1004 NN denotes levels
T13321 994-997 DT denotes the
T13320 985-993 VB denotes compared
T13319 980-984 RB denotes thus
T13318 977-979 PRP denotes We
T13317 970-975 NN denotes ng/ml
T13316 963-969 CD denotes 10–100
T13315 960-962 IN denotes at
T13314 951-959 VB denotes obtained
T13313 947-950 VB denotes was
T13312 941-946 NN denotes IL-10
T13311 938-940 IN denotes by
T13310 927-937 NN denotes inhibition
T13309 918-926 JJ denotes complete
T13308 914-917 RB denotes not
T13307 910-913 CC denotes but
T13306 902-909 JJ denotes maximal
T13305 898-901 DT denotes the
T13304 894-897 CC denotes and
T13303 892-893 -COMMA- denotes ,
T13302 887-892 NN denotes IL-10
T13301 881-886 NN denotes ng/ml
T13300 879-880 CD denotes 1
T13299 876-878 IN denotes of
T13298 867-875 NN denotes presence
T13297 863-866 DT denotes the
T13296 860-862 IN denotes in
T13295 854-859 NN denotes IFN-γ
T13294 851-853 IN denotes of
T13293 843-850 NN denotes amounts
T13292 831-842 JJ denotes significant
T13291 823-830 VB denotes produce
T13290 820-822 TO denotes to
T13289 815-819 JJ denotes able
T13288 810-814 VB denotes were
T13287 804-809 NN denotes cells
T13286 802-803 NN denotes T
T13285 797-801 JJ denotes CD4+
T13284 794-796 NN denotes RA
T13283 792-793 -COMMA- denotes ,
T13282 785-792 RB denotes However
T13281 778-783 NN denotes IL-10
T13280 772-777 NN denotes ng/ml
T13279 770-771 CD denotes 1
T13278 767-769 IN denotes as
T13277 763-766 JJ denotes low
T13276 760-762 RB denotes as
T13275 745-759 NN denotes concentrations
T13274 742-744 IN denotes at
T13273 732-741 VB denotes inhibited
T13272 725-731 RB denotes mostly
T13271 721-724 VB denotes was
T13270 715-720 NN denotes cells
T13269 713-714 NN denotes T
T13268 708-712 JJ denotes CD4+
T13267 701-707 JJ denotes normal
T13266 691-700 VB denotes activated
T13265 688-690 IN denotes by
T13264 677-687 NN denotes production
T13263 671-676 NN denotes IFN-γ
T13262 669-670 -COMMA- denotes ,
T13261 668-669 CD denotes 1
T13260 663-667 NNP denotes Fig.
T13259 660-662 IN denotes in
T13258 654-659 VB denotes shown
T13257 651-653 IN denotes As
T13256 644-649 NN denotes ELISA
T13255 641-643 IN denotes by
T13254 632-640 VB denotes measured
T13253 628-631 VB denotes was
T13252 617-627 NN denotes production
T13251 611-616 NN denotes IFN-γ
T13250 607-610 CC denotes and
T13249 605-606 -COMMA- denotes ,
T13248 600-605 NN denotes hours
T13247 597-599 CD denotes 36
T13246 593-596 IN denotes for
T13245 587-592 NN denotes IL-10
T13244 584-586 IN denotes of
T13243 569-583 NN denotes concentrations
T13242 561-568 JJ denotes diluted
T13241 553-560 IN denotes without
T13240 550-552 CC denotes or
T13239 545-549 IN denotes with
T13238 536-544 NN denotes antibody
T13237 526-535 JJ denotes anti-CD28
T13236 522-525 CC denotes and
T13235 513-521 NN denotes antibody
T13234 504-512 JJ denotes anti-CD3
T13233 492-503 VB denotes immobilized
T13232 489-491 IN denotes by
T13231 478-488 VB denotes stimulated
T13230 473-477 VB denotes were
T13229 464-472 NN denotes controls
T13228 456-463 JJ denotes healthy
T13227 450-455 CD denotes three
T13226 445-449 IN denotes from
T13225 441-444 CC denotes and
T13224 438-440 NN denotes RA
T13223 431-437 JJ denotes active
T13222 426-430 IN denotes with
T13221 417-425 NN denotes patients
T13220 411-416 CD denotes three
T13219 406-410 IN denotes from
T13218 400-405 NN denotes cells
T13217 398-399 NN denotes T
T13497 1875-1877 IN denotes by
T13496 1864-1874 NN denotes production
T13495 1859-1863 NN denotes IL-2
T13494 1850-1858 VB denotes compared
T13493 1847-1849 PRP denotes we
T13492 1845-1846 -COMMA- denotes ,
T13491 1837-1845 NN denotes addition
T13490 1834-1836 IN denotes In
T13489 1831-1832 -RRB- denotes )
T13488 1829-1831 NN denotes 2a
T13487 1824-1828 NN denotes Fig.
T13486 1823-1824 -LRB- denotes (
T13485 1817-1822 NN denotes cells
T13484 1815-1816 NN denotes T
T13483 1810-1814 JJ denotes CD4+
T13482 1803-1809 JJ denotes normal
T13481 1799-1802 VB denotes did
T13480 1794-1798 IN denotes than
T13479 1788-1793 NN denotes IL-10
T13478 1782-1787 NN denotes ng/ml
T13477 1780-1781 CD denotes 1
T13476 1777-1779 IN denotes of
T13475 1768-1776 NN denotes presence
T13474 1764-1767 DT denotes the
T13473 1761-1763 IN denotes in
T13472 1755-1760 NN denotes IFN-γ
T13471 1752-1754 IN denotes of
T13470 1745-1751 NN denotes levels
T13469 1738-1744 JJ denotes higher
T13468 1729-1737 VB denotes produced
T13467 1720-1728 NN denotes patients
T13466 1717-1719 NN denotes RA
T13465 1710-1716 JJ denotes active
T13464 1705-1709 IN denotes from
T13463 1699-1704 NN denotes cells
T13462 1697-1698 NN denotes T
T13461 1692-1696 JJ denotes CD4+
T13460 1690-1691 -COMMA- denotes ,
T13459 1679-1690 NN denotes consequence
T13458 1677-1678 DT denotes a
T13457 1674-1676 IN denotes As
T13456 1671-1672 -RRB- denotes )
T13455 1669-1671 NN denotes 2b
T13454 1664-1668 NNP denotes Fig.
T13453 1663-1664 -LRB- denotes (
T13452 1661-1662 -RRB- denotes )
T13451 1660-1661 NN denotes %
T13450 1657-1660 CD denotes 7.9
T13449 1655-1656 -COLON- denotes ±
T13448 1650-1654 CD denotes 65.8
T13447 1648-1649 -COMMA- denotes ,
T13446 1640-1648 NN denotes controls
T13445 1638-1639 -COLON- denotes ;
T13444 1637-1638 NN denotes %
T13443 1633-1637 CD denotes 14.4
T13442 1631-1632 CC denotes ±
T13441 1626-1630 CD denotes 45.6
T13440 1624-1625 -COMMA- denotes ,
T13439 1622-1624 NN denotes RA
T13438 1613-1621 JJ denotes inactive
T13437 1611-1612 -COLON- denotes ;
T13436 1610-1611 NN denotes %
T13435 1606-1610 CD denotes 14.4
T13434 1604-1605 CC denotes ±
T13433 1600-1603 CD denotes 2.9
T13216 393-397 JJ denotes CD4+
T13215 390-392 NN denotes PB
T13214 381-389 VB denotes purified
T13213 379-380 -COMMA- denotes ,
T13212 374-379 NN denotes IL-10
T13211 371-373 TO denotes to
T13210 365-370 NN denotes cells
T13209 363-364 NN denotes T
T13208 358-362 JJ denotes CD4+
T13207 355-357 NN denotes RA
T13206 352-354 IN denotes of
T13205 337-351 NN denotes responsiveness
T13204 333-336 DT denotes the
T13203 324-332 VB denotes evaluate
T13202 321-323 TO denotes To
T13201 318-319 -RRB- denotes ]
T13200 316-318 CD denotes 24
T13199 315-316 -LRB- denotes [
T13198 306-314 NN denotes 3-kinase
T13197 285-305 NN denotes phosphatidylinositol
T13196 282-284 IN denotes of
T13195 274-281 NN denotes binding
T13194 270-273 CC denotes and
T13193 254-269 NN denotes phosphorylation
T13192 245-253 NN denotes tyrosine
T13191 240-244 NN denotes CD28
T13190 229-239 VB denotes inhibiting
T13189 226-228 IN denotes by
T13188 217-225 NN denotes response
T13187 212-216 DT denotes this
T13186 203-211 VB denotes suppress
T13185 194-202 RB denotes directly
T13184 190-193 MD denotes can
T13183 184-189 NN denotes IL-10
T13182 180-183 CC denotes and
T13181 178-179 -COMMA- denotes ,
T13180 168-178 NN denotes production
T13179 159-167 NN denotes cytokine
T13178 152-158 NN denotes T-cell
T13177 135-151 JJ denotes antigen-specific
T13176 125-134 JJ denotes effective
T13175 121-124 IN denotes for
T13174 113-120 JJ denotes crucial
T13173 110-112 VB denotes is
T13172 102-109 NN denotes pathway
T13171 88-101 JJ denotes costimulatory
T13170 83-87 NN denotes CD28
T13169 79-82 DT denotes The
T13168 73-78 NN denotes cells
T13167 71-72 NN denotes T
T13166 66-70 JJ denotes CD4+
T13165 63-65 NN denotes RA
T13164 60-62 IN denotes in
T13163 49-59 NN denotes production
T13162 43-48 NN denotes IFN-γ
T13161 40-42 IN denotes of
T13160 29-39 NN denotes inhibition
T13159 23-28 NN denotes IL-10
T13158 20-22 TO denotes to
T13157 9-19 NN denotes Resistance
R6415 T13157 T13158 arg1Of Resistance,to
R6416 T13157 T13164 arg1Of Resistance,in
R6417 T13160 T13158 arg2Of inhibition,to
R6418 T13160 T13159 arg1Of inhibition,IL-10
R6419 T13160 T13161 arg1Of inhibition,of
R6420 T13163 T13161 arg2Of production,of
R6421 T13163 T13162 arg1Of production,IFN-γ
R6422 T13168 T13164 arg2Of cells,in
R6423 T13168 T13165 arg1Of cells,RA
R6424 T13168 T13166 arg1Of cells,CD4+
R6425 T13168 T13167 arg1Of cells,T
R6426 T13172 T13169 arg1Of pathway,The
R6427 T13172 T13170 arg1Of pathway,CD28
R6428 T13172 T13171 arg1Of pathway,costimulatory
R6429 T13172 T13173 arg1Of pathway,is
R6430 T13172 T13174 arg1Of pathway,crucial
R6431 T13173 T13182 arg1Of is,and
R6432 T13174 T13173 arg2Of crucial,is
R6433 T13174 T13175 arg1Of crucial,for
R6434 T13180 T13175 arg2Of production,for
R6435 T13180 T13176 arg1Of production,effective
R6436 T13180 T13177 arg1Of production,antigen-specific
R6437 T13180 T13178 arg1Of production,T-cell
R6438 T13180 T13179 arg1Of production,cytokine
R6439 T13182 T13181 arg1Of and,","
R6440 T13183 T13184 arg1Of IL-10,can
R6441 T13183 T13186 arg1Of IL-10,suppress
R6442 T13183 T13190 arg1Of IL-10,inhibiting
R6443 T13186 T13182 arg2Of suppress,and
R6444 T13186 T13184 arg2Of suppress,can
R6445 T13186 T13185 arg1Of suppress,directly
R6446 T13186 T13189 arg1Of suppress,by
R6447 T13188 T13186 arg2Of response,suppress
R6448 T13188 T13187 arg1Of response,this
R6449 T13190 T13189 arg2Of inhibiting,by
R6450 T13190 T13199 arg1Of inhibiting,[
R6451 T13193 T13191 arg1Of phosphorylation,CD28
R6452 T13193 T13192 arg1Of phosphorylation,tyrosine
R6453 T13193 T13194 arg1Of phosphorylation,and
R6454 T13194 T13190 arg2Of and,inhibiting
R6455 T13195 T13194 arg2Of binding,and
R6456 T13195 T13196 arg1Of binding,of
R6457 T13198 T13196 arg2Of 3-kinase,of
R6458 T13198 T13197 arg1Of 3-kinase,phosphatidylinositol
R6459 T13200 T13199 arg2Of 24,[
R6460 T13201 T13199 arg3Of ],[
R6461 T13203 T13202 arg1Of evaluate,To
R6462 T13205 T13203 arg2Of responsiveness,evaluate
R6463 T13205 T13204 arg1Of responsiveness,the
R6464 T13205 T13206 arg1Of responsiveness,of
R6465 T13205 T13211 arg1Of responsiveness,to
R6466 T13210 T13206 arg2Of cells,of
R6467 T13210 T13207 arg1Of cells,RA
R6468 T13210 T13208 arg1Of cells,CD4+
R6469 T13210 T13209 arg1Of cells,T
R6470 T13212 T13211 arg2Of IL-10,to
R6471 T13218 T13214 arg2Of cells,purified
R6472 T13218 T13215 arg1Of cells,PB
R6473 T13218 T13216 arg1Of cells,CD4+
R6474 T13218 T13217 arg1Of cells,T
R6475 T13218 T13219 arg1Of cells,from
R6476 T13218 T13226 arg1Of cells,from
R6477 T13218 T13230 arg1Of cells,were
R6478 T13218 T13231 arg2Of cells,stimulated
R6479 T13219 T13225 arg1Of from,and
R6480 T13221 T13219 arg2Of patients,from
R6481 T13221 T13220 arg1Of patients,three
R6482 T13221 T13222 arg1Of patients,with
R6483 T13224 T13222 arg2Of RA,with
R6484 T13224 T13223 arg1Of RA,active
R6485 T13226 T13225 arg2Of from,and
R6486 T13229 T13226 arg2Of controls,from
R6487 T13229 T13227 arg1Of controls,three
R6488 T13229 T13228 arg1Of controls,healthy
R6489 T13231 T13230 arg2Of stimulated,were
R6490 T13231 T13250 arg1Of stimulated,and
R6491 T13235 T13233 arg2Of antibody,immobilized
R6492 T13235 T13234 arg1Of antibody,anti-CD3
R6493 T13235 T13236 arg1Of antibody,and
R6494 T13236 T13231 arg1Of and,stimulated
R6495 T13236 T13232 arg2Of and,by
R6496 T13236 T13239 arg1Of and,with
R6497 T13236 T13241 arg1Of and,without
R6498 T13238 T13236 arg2Of antibody,and
R6499 T13238 T13237 arg1Of antibody,anti-CD28
R6500 T13239 T13240 arg1Of with,or
R6501 T13241 T13240 arg2Of without,or
R6502 T13243 T13239 arg2Of concentrations,with
R6503 T13243 T13241 arg2Of concentrations,without
R6504 T13243 T13242 arg1Of concentrations,diluted
R6505 T13243 T13244 arg1Of concentrations,of
R6506 T13245 T13244 arg2Of IL-10,of
R6507 T13245 T13246 arg1Of IL-10,for
R6508 T13248 T13246 arg2Of hours,for
R6509 T13248 T13247 arg1Of hours,36
R6510 T13250 T13202 modOf and,To
R6511 T13250 T13213 arg1Of and,","
R6512 T13250 T13249 arg1Of and,","
R6513 T13252 T13251 arg1Of production,IFN-γ
R6514 T13252 T13253 arg1Of production,was
R6515 T13252 T13254 arg2Of production,measured
R6516 T13254 T13250 arg2Of measured,and
R6517 T13254 T13253 arg2Of measured,was
R6518 T13256 T13254 arg1Of ELISA,measured
R6519 T13256 T13255 arg2Of ELISA,by
R6520 T13258 T13257 arg2Of shown,As
R6521 T13258 T13259 arg1Of shown,in
R6522 T13260 T13259 arg2Of Fig.,in
R6523 T13260 T13261 arg1Of Fig.,1
R6524 T13264 T13263 arg1Of production,IFN-γ
R6525 T13264 T13265 arg1Of production,by
R6526 T13264 T13271 arg1Of production,was
R6527 T13264 T13273 arg2Of production,inhibited
R6528 T13270 T13265 arg2Of cells,by
R6529 T13270 T13266 arg2Of cells,activated
R6530 T13270 T13267 arg1Of cells,normal
R6531 T13270 T13268 arg1Of cells,CD4+
R6532 T13270 T13269 arg1Of cells,T
R6533 T13273 T13257 arg1Of inhibited,As
R6534 T13273 T13262 arg1Of inhibited,","
R6535 T13273 T13271 arg2Of inhibited,was
R6536 T13273 T13272 arg1Of inhibited,mostly
R6537 T13273 T13274 arg1Of inhibited,at
R6538 T13273 T13276 arg1Of inhibited,as
R6539 T13275 T13274 arg2Of concentrations,at
R6540 T13276 T13277 arg1Of as,low
R6541 T13276 T13278 arg1Of as,as
R6542 T13279 T13280 arg1Of 1,ng/ml
R6543 T13281 T13278 arg2Of IL-10,as
R6544 T13281 T13279 arg1Of IL-10,1
R6545 T13287 T13284 arg1Of cells,RA
R6546 T13287 T13285 arg1Of cells,CD4+
R6547 T13287 T13286 arg1Of cells,T
R6548 T13287 T13288 arg1Of cells,were
R6549 T13287 T13289 arg1Of cells,able
R6550 T13287 T13291 arg1Of cells,produce
R6551 T13288 T13304 arg1Of were,and
R6552 T13289 T13288 arg2Of able,were
R6553 T13291 T13289 arg2Of produce,able
R6554 T13291 T13290 arg1Of produce,to
R6555 T13291 T13296 arg1Of produce,in
R6556 T13293 T13291 arg2Of amounts,produce
R6557 T13293 T13292 arg1Of amounts,significant
R6558 T13293 T13294 arg1Of amounts,of
R6559 T13295 T13294 arg2Of IFN-γ,of
R6560 T13296 T13297 arg1Of in,the
R6561 T13296 T13299 arg1Of in,of
R6562 T13298 T13296 arg2Of presence,in
R6563 T13300 T13301 arg1Of 1,ng/ml
R6564 T13302 T13296 arg3Of IL-10,in
R6565 T13302 T13300 arg1Of IL-10,1
R6566 T13304 T13282 arg1Of and,However
R6567 T13304 T13283 arg1Of and,","
R6568 T13304 T13303 arg1Of and,","
R6569 T13306 T13307 arg1Of maximal,but
R6570 T13309 T13307 arg2Of complete,but
R6571 T13309 T13308 arg1Of complete,not
R6572 T13310 T13305 arg1Of inhibition,the
R6573 T13310 T13306 arg1Of inhibition,maximal
R6574 T13310 T13309 arg1Of inhibition,complete
R6575 T13310 T13311 arg1Of inhibition,by
R6576 T13310 T13313 arg1Of inhibition,was
R6577 T13310 T13314 arg2Of inhibition,obtained
R6578 T13312 T13311 arg2Of IL-10,by
R6579 T13314 T13304 arg2Of obtained,and
R6580 T13314 T13313 arg2Of obtained,was
R6581 T13314 T13315 arg1Of obtained,at
R6582 T13317 T13315 arg2Of ng/ml,at
R6583 T13317 T13316 arg1Of ng/ml,10–100
R6584 T13318 T13320 arg1Of We,compared
R6585 T13320 T13319 arg1Of compared,thus
R6586 T13320 T13326 arg1Of compared,by
R6587 T13320 T13330 arg1Of compared,after
R6588 T13320 T13335 arg1Of compared,in
R6589 T13322 T13320 arg2Of levels,compared
R6590 T13322 T13321 arg1Of levels,the
R6591 T13322 T13323 arg1Of levels,of
R6592 T13325 T13323 arg2Of production,of
R6593 T13325 T13324 arg1Of production,IFN-γ
R6594 T13329 T13326 arg2Of cells,by
R6595 T13329 T13327 arg1Of cells,CD4+
R6596 T13329 T13328 arg1Of cells,T
R6597 T13331 T13332 arg1Of CD3,and
R6598 T13333 T13332 arg2Of CD28,and
R6599 T13334 T13330 arg2Of costimulation,after
R6600 T13334 T13331 arg1Of costimulation,CD3
R6601 T13334 T13333 arg1Of costimulation,CD28
R6602 T13335 T13336 arg1Of in,the
R6603 T13335 T13338 arg1Of in,of
R6604 T13337 T13335 arg2Of presence,in
R6605 T13339 T13340 arg1Of 1,ng/ml
R6606 T13341 T13335 arg3Of IL-10,in
R6607 T13341 T13339 arg1Of IL-10,1
R6608 T13341 T13342 arg1Of IL-10,in
R6609 T13341 T13376 arg1Of IL-10,in
R6610 T13342 T13375 arg1Of in,and
R6611 T13344 T13343 arg1Of patients,RA
R6612 T13344 T13345 arg1Of patients,with
R6613 T13344 T13348 arg1Of patients,(
R6614 T13344 T13359 arg1Of patients,and
R6615 T13347 T13345 arg2Of disease,with
R6616 T13347 T13346 arg1Of disease,active
R6617 T13351 T13348 arg2Of joints,(
R6618 T13351 T13349 arg1Of joints,multiple
R6619 T13351 T13350 arg1Of joints,inflammatory
R6620 T13351 T13352 arg1Of joints,","
R6621 T13357 T13352 arg2Of mg/l,","
R6622 T13357 T13353 arg1Of mg/l,CRP
R6623 T13357 T13354 arg1Of mg/l,level
R6624 T13357 T13355 arg1Of mg/l,≥
R6625 T13357 T13356 arg1Of mg/l,10
R6626 T13358 T13348 arg3Of ),(
R6627 T13359 T13342 arg2Of and,in
R6628 T13361 T13359 arg2Of disease,and
R6629 T13361 T13360 arg1Of disease,inactive
R6630 T13361 T13362 arg1Of disease,(
R6631 T13361 T13372 arg1Of disease,[
R6632 T13363 T13362 arg2Of in,(
R6633 T13364 T13363 arg2Of remission,in
R6634 T13364 T13365 arg1Of remission,","
R6635 T13367 T13365 arg2Of level,","
R6636 T13367 T13366 arg1Of level,CRP
R6637 T13367 T13370 arg1Of level,mg/l
R6638 T13369 T13368 arg1Of 10,<
R6639 T13370 T13369 arg1Of mg/l,10
R6640 T13371 T13362 arg3Of ),(
R6641 T13373 T13372 arg2Of 26,[
R6642 T13374 T13372 arg3Of ],[
R6643 T13376 T13375 arg2Of in,and
R6644 T13378 T13376 arg2Of controls,in
R6645 T13378 T13377 arg1Of controls,healthy
R6646 T13379 T13380 arg1Of There,were
R6647 T13380 T13399 arg1Of were,but
R6648 T13383 T13382 arg1Of significant,statistically
R6649 T13384 T13380 arg2Of differences,were
R6650 T13384 T13381 arg1Of differences,no
R6651 T13384 T13383 arg1Of differences,significant
R6652 T13384 T13385 arg1Of differences,in
R6653 T13387 T13385 arg2Of production,in
R6654 T13387 T13386 arg1Of production,IFN-γ
R6655 T13387 T13388 arg1Of production,without
R6656 T13389 T13388 arg2Of IL-10,without
R6657 T13389 T13390 arg1Of IL-10,among
R6658 T13393 T13390 arg2Of groups,among
R6659 T13393 T13391 arg1Of groups,these
R6660 T13393 T13392 arg1Of groups,three
R6661 T13393 T13394 arg1Of groups,(
R6662 T13396 T13394 arg2Of 2a,(
R6663 T13396 T13395 arg1Of 2a,Fig.
R6664 T13397 T13394 arg3Of ),(
R6665 T13399 T13398 arg1Of but,","
R6666 T13402 T13400 arg1Of effect,the
R6667 T13402 T13401 arg1Of effect,inhibitory
R6668 T13402 T13403 arg1Of effect,of
R6669 T13402 T13405 arg1Of effect,on
R6670 T13402 T13408 arg1Of effect,was
R6671 T13402 T13410 arg2Of effect,limited
R6672 T13404 T13403 arg2Of IL-10,of
R6673 T13407 T13405 arg2Of production,on
R6674 T13407 T13406 arg1Of production,IFN-γ
R6675 T13410 T13399 arg2Of limited,but
R6676 T13410 T13408 arg2Of limited,was
R6677 T13410 T13409 arg1Of limited,significantly
R6678 T13410 T13411 arg1Of limited,in
R6679 T13410 T13416 arg1Of limited,as
R6680 T13410 T13453 arg1Of limited,(
R6681 T13415 T13411 arg2Of group,in
R6682 T13415 T13412 arg1Of group,the
R6683 T13415 T13413 arg1Of group,active
R6684 T13415 T13414 arg1Of group,RA
R6685 T13417 T13416 arg2Of compared,as
R6686 T13417 T13418 arg1Of compared,with
R6687 T13422 T13419 arg1Of group,the
R6688 T13422 T13420 arg1Of group,inactive
R6689 T13422 T13421 arg1Of group,RA
R6690 T13422 T13423 arg1Of group,and
R6691 T13423 T13418 arg2Of and,with
R6692 T13425 T13423 arg2Of controls,and
R6693 T13425 T13424 arg1Of controls,healthy
R6694 T13425 T13426 arg1Of controls,(
R6695 T13428 T13426 arg2Of decrease,(
R6696 T13428 T13427 arg1Of decrease,percentage
R6697 T13428 T13429 arg1Of decrease,:
R6698 T13431 T13429 arg2Of RA,:
R6699 T13431 T13430 arg1Of RA,active
R6700 T13431 T13432 arg1Of RA,","
R6701 T13431 T13437 arg1Of RA,;
R6702 T13433 T13434 arg1Of 2.9,±
R6703 T13435 T13434 arg2Of 14.4,±
R6704 T13436 T13432 arg2Of %,","
R6705 T13436 T13433 arg1Of %,2.9
R6706 T13436 T13435 arg1Of %,14.4
R6707 T13439 T13437 arg2Of RA,;
R6708 T13439 T13438 arg1Of RA,inactive
R6709 T13439 T13440 arg1Of RA,","
R6710 T13439 T13445 arg1Of RA,;
R6711 T13441 T13442 arg1Of 45.6,±
R6712 T13443 T13442 arg2Of 14.4,±
R6713 T13444 T13440 arg2Of %,","
R6714 T13444 T13441 arg1Of %,45.6
R6715 T13444 T13443 arg1Of %,14.4
R6716 T13446 T13445 arg2Of controls,;
R6717 T13446 T13447 arg1Of controls,","
R6718 T13451 T13447 arg2Of %,","
R6719 T13451 T13448 arg1Of %,65.8
R6720 T13451 T13449 arg1Of %,±
R6721 T13451 T13450 arg1Of %,7.9
R6722 T13452 T13426 arg3Of ),(
R6723 T13455 T13453 arg2Of 2b,(
R6724 T13455 T13454 arg1Of 2b,Fig.
R6725 T13456 T13453 arg3Of ),(
R6726 T13459 T13457 arg2Of consequence,As
R6727 T13459 T13458 arg1Of consequence,a
R6728 T13463 T13461 arg1Of cells,CD4+
R6729 T13463 T13462 arg1Of cells,T
R6730 T13463 T13464 arg1Of cells,from
R6731 T13463 T13468 arg1Of cells,produced
R6732 T13467 T13464 arg2Of patients,from
R6733 T13467 T13465 arg1Of patients,active
R6734 T13467 T13466 arg1Of patients,RA
R6735 T13468 T13457 arg1Of produced,As
R6736 T13468 T13460 arg1Of produced,","
R6737 T13468 T13473 arg1Of produced,in
R6738 T13470 T13468 arg2Of levels,produced
R6739 T13470 T13469 arg1Of levels,higher
R6740 T13470 T13471 arg1Of levels,of
R6741 T13472 T13471 arg2Of IFN-γ,of
R6742 T13475 T13473 arg2Of presence,in
R6743 T13475 T13474 arg1Of presence,the
R6744 T13475 T13476 arg1Of presence,of
R6745 T13475 T13480 arg1Of presence,than
R6746 T13477 T13478 arg1Of 1,ng/ml
R6747 T13479 T13476 arg2Of IL-10,of
R6748 T13479 T13477 arg1Of IL-10,1
R6749 T13481 T13480 arg2Of did,than
R6750 T13485 T13481 arg1Of cells,did
R6751 T13485 T13482 arg1Of cells,normal
R6752 T13485 T13483 arg1Of cells,CD4+
R6753 T13485 T13484 arg1Of cells,T
R6754 T13485 T13486 arg1Of cells,(
R6755 T13488 T13486 arg2Of 2a,(
R6756 T13488 T13487 arg1Of 2a,Fig.
R6757 T13489 T13486 arg3Of ),(
R6758 T13491 T13490 arg2Of addition,In
R6759 T13493 T13494 arg1Of we,compared
R6760 T13494 T13490 arg1Of compared,In
R6761 T13494 T13492 arg1Of compared,","
R6762 T13494 T13497 arg1Of compared,by
R6763 T13494 T13501 arg1Of compared,after
R6764 T13496 T13494 arg2Of production,compared
R6765 T13496 T13495 arg1Of production,IL-2
R6766 T13500 T13497 arg2Of cells,by
R6767 T13500 T13498 arg1Of cells,CD4+
R6768 T13500 T13499 arg1Of cells,T
R6769 T13502 T13503 arg1Of CD3,and
R6770 T13504 T13503 arg2Of CD28,and
R6771 T13505 T13501 arg2Of costimulation,after
R6772 T13505 T13502 arg1Of costimulation,CD3
R6773 T13505 T13504 arg1Of costimulation,CD28
R6774 T13505 T13506 arg1Of costimulation,in
R6775 T13505 T13516 arg1Of costimulation,in
R6776 T13506 T13515 arg1Of in,and
R6777 T13508 T13506 arg2Of presence,in
R6778 T13508 T13507 arg1Of presence,the
R6779 T13508 T13509 arg1Of presence,of
R6780 T13508 T13511 arg1Of presence,in
R6781 T13510 T13509 arg2Of IL-10,of
R6782 T13514 T13511 arg2Of patients,in
R6783 T13514 T13512 arg1Of patients,active
R6784 T13514 T13513 arg1Of patients,RA
R6785 T13516 T13515 arg2Of in,and
R6786 T13518 T13516 arg2Of controls,in
R6787 T13518 T13517 arg1Of controls,healthy
R6788 T13522 T13521 arg1Of production,IL-2
R6789 T13522 T13523 arg1Of production,was
R6790 T13522 T13525 arg2Of production,affected
R6791 T13525 T13519 arg1Of affected,Similarly
R6792 T13525 T13520 arg1Of affected,","
R6793 T13525 T13523 arg2Of affected,was
R6794 T13525 T13524 arg1Of affected,not
R6795 T13525 T13542 arg1Of affected,","
R6796 T13525 T13543 arg1Of affected,while
R6797 T13527 T13528 arg1Of 1,ng/ml
R6798 T13529 T13525 arg1Of IL-10,affected
R6799 T13529 T13526 arg2Of IL-10,by
R6800 T13529 T13527 arg1Of IL-10,1
R6801 T13529 T13530 arg1Of IL-10,in
R6802 T13532 T13530 arg2Of patients,in
R6803 T13532 T13531 arg1Of patients,RA
R6804 T13532 T13533 arg1Of patients,(
R6805 T13535 T13533 arg2Of decrease,(
R6806 T13535 T13534 arg1Of decrease,percentage
R6807 T13535 T13536 arg1Of decrease,","
R6808 T13540 T13536 arg2Of %,","
R6809 T13540 T13537 arg1Of %,-2.1
R6810 T13540 T13538 arg1Of %,±
R6811 T13540 T13539 arg1Of %,13.8
R6812 T13541 T13533 arg3Of ),(
R6813 T13544 T13545 arg1Of it,was
R6814 T13544 T13547 arg2Of it,reduced
R6815 T13547 T13543 arg2Of reduced,while
R6816 T13547 T13545 arg2Of reduced,was
R6817 T13547 T13546 arg1Of reduced,significantly
R6818 T13547 T13548 arg1Of reduced,in
R6819 T13547 T13551 arg1Of reduced,(
R6820 T13550 T13548 arg2Of controls,in
R6821 T13550 T13549 arg1Of controls,healthy
R6822 T13554 T13553 arg1Of 13.7,±
R6823 T13555 T13551 arg2Of %,(
R6824 T13555 T13552 arg1Of %,61.1
R6825 T13555 T13554 arg1Of %,13.7
R6826 T13555 T13556 arg1Of %,;
R6827 T13557 T13556 arg2Of P,;
R6828 T13557 T13558 arg1Of P,<
R6829 T13557 T13559 arg1Of P,0.05
R6830 T13560 T13551 arg3Of ),(
R6831 T13561 T13562 arg1Of Taken,together
R6832 T13565 T13564 arg1Of results,these
R6833 T13565 T13566 arg1Of results,indicate
R6834 T13566 T13561 modOf indicate,Taken
R6835 T13566 T13563 arg1Of indicate,","
R6836 T13571 T13568 arg1Of cells,RA
R6837 T13571 T13569 arg1Of cells,CD4+
R6838 T13571 T13570 arg1Of cells,T
R6839 T13571 T13572 arg1Of cells,become
R6840 T13571 T13574 arg1Of cells,susceptible
R6841 T13572 T13566 arg2Of become,indicate
R6842 T13572 T13567 arg1Of become,that
R6843 T13572 T13581 arg1Of become,during
R6844 T13574 T13572 arg2Of susceptible,become
R6845 T13574 T13573 arg1Of susceptible,less
R6846 T13574 T13575 arg1Of susceptible,to
R6847 T13578 T13575 arg2Of effect,to
R6848 T13578 T13576 arg1Of effect,the
R6849 T13578 T13577 arg1Of effect,immunoregulatory
R6850 T13578 T13579 arg1Of effect,of
R6851 T13580 T13579 arg2Of IL-10,of
R6852 T13584 T13581 arg2Of phase,during
R6853 T13584 T13582 arg1Of phase,the
R6854 T13584 T13583 arg1Of phase,active
R7458 T14856 T14855 arg2Of expression,Increased
R7459 T14856 T14857 arg1Of expression,of
R7460 T14856 T14861 arg1Of expression,on
R7461 T14860 T14857 arg2Of IL-10R1,of
R7462 T14860 T14858 arg1Of IL-10R1,cell
R7463 T14860 T14859 arg1Of IL-10R1,surface
R7464 T14865 T14861 arg2Of cells,on
R7465 T14865 T14862 arg1Of cells,RA
R7466 T14865 T14863 arg1Of cells,CD4+
R7467 T14865 T14864 arg1Of cells,T
R7468 T14869 T14866 arg1Of complex,The
R7469 T14869 T14867 arg1Of complex,functional
R7470 T14869 T14868 arg1Of complex,receptor
R7471 T14869 T14870 arg1Of complex,of
R7472 T14869 T14872 arg1Of complex,consists
R7473 T14871 T14870 arg2Of IL-10,of
R7474 T14872 T14873 arg1Of consists,of
R7475 T14875 T14873 arg2Of subunits,of
R7476 T14875 T14874 arg1Of subunits,two
R7477 T14875 T14876 arg1Of subunits,","
R7478 T14881 T14877 arg1Of IL-10R1,the
R7479 T14881 T14878 arg1Of IL-10R1,primary
R7480 T14881 T14879 arg1Of IL-10R1,ligand-binding
R7481 T14881 T14880 arg1Of IL-10R1,component
R7482 T14881 T14882 arg1Of IL-10R1,and
R7483 T14882 T14876 arg2Of and,","
R7484 T14888 T14882 arg2Of IL-10R,and
R7485 T14888 T14883 arg1Of IL-10R,the
R7486 T14888 T14884 arg1Of IL-10R,accessory
R7487 T14888 T14885 arg1Of IL-10R,component
R7488 T14888 T14886 arg1Of IL-10R,type
R7489 T14888 T14887 arg1Of IL-10R,2
R7490 T14888 T14889 arg1Of IL-10R,[
R7491 T14890 T14889 arg2Of 1,[
R7492 T14891 T14889 arg3Of ],[
R7493 T14893 T14892 arg1Of expression,IL-10R1
R7494 T14893 T14894 arg1Of expression,plays
R7495 T14894 T14898 arg1Of plays,in
R7496 T14897 T14894 arg2Of role,plays
R7497 T14897 T14895 arg1Of role,a
R7498 T14897 T14896 arg1Of role,critical
R7499 T14900 T14898 arg2Of responses,in
R7500 T14900 T14899 arg1Of responses,cellular
R7501 T14900 T14901 arg1Of responses,to
R7502 T14902 T14901 arg2Of IL-10,to
R7503 T14902 T14903 arg1Of IL-10,[
R7504 T14904 T14903 arg2Of 29,[
R7505 T14905 T14903 arg3Of ],[
R7506 T14907 T14906 arg1Of examine,To
R7507 T14910 T14909 arg1Of resistance,the
R7508 T14910 T14911 arg1Of resistance,to
R7509 T14910 T14914 arg1Of resistance,in
R7510 T14910 T14919 arg1Of resistance,was
R7511 T14910 T14920 arg1Of resistance,due
R7512 T14913 T14911 arg2Of inhibition,to
R7513 T14913 T14912 arg1Of inhibition,IL-10
R7514 T14918 T14914 arg2Of cells,in
R7515 T14918 T14915 arg1Of cells,RA
R7516 T14918 T14916 arg1Of cells,CD4+
R7517 T14918 T14917 arg1Of cells,T
R7518 T14919 T14907 arg2Of was,examine
R7519 T14919 T14908 arg1Of was,whether
R7520 T14920 T14919 arg2Of due,was
R7521 T14920 T14921 arg1Of due,to
R7522 T14924 T14921 arg2Of expression,to
R7523 T14924 T14922 arg2Of expression,limited
R7524 T14924 T14923 arg1Of expression,receptor
R7525 T14929 T14926 arg1Of expression,the
R7526 T14929 T14927 arg1Of expression,cell
R7527 T14929 T14928 arg1Of expression,surface
R7528 T14929 T14930 arg1Of expression,of
R7529 T14929 T14932 arg1Of expression,on
R7530 T14929 T14942 arg1Of expression,from
R7531 T14929 T14945 arg1Of expression,was
R7532 T14929 T14946 arg2Of expression,determined
R7533 T14931 T14930 arg2Of IL-10R1,of
R7534 T14932 T14941 arg1Of on,and
R7535 T14936 T14932 arg2Of cells,on
R7536 T14936 T14933 arg1Of cells,PB
R7537 T14936 T14934 arg1Of cells,CD4+
R7538 T14936 T14935 arg1Of cells,T
R7539 T14936 T14937 arg1Of cells,from
R7540 T14940 T14937 arg2Of patients,from
R7541 T14940 T14938 arg1Of patients,active
R7542 T14940 T14939 arg1Of patients,RA
R7543 T14942 T14941 arg2Of from,and
R7544 T14944 T14942 arg2Of controls,from
R7545 T14944 T14943 arg1Of controls,healthy
R7546 T14946 T14906 modOf determined,To
R7547 T14946 T14925 arg1Of determined,","
R7548 T14946 T14945 arg2Of determined,was
R7549 T14950 T14946 arg1Of analysis,determined
R7550 T14950 T14947 arg2Of analysis,by
R7551 T14950 T14948 arg1Of analysis,flow
R7552 T14950 T14949 arg1Of analysis,cytometric
R7553 T14952 T14951 arg2Of shown,As
R7554 T14952 T14953 arg1Of shown,in
R7555 T14955 T14953 arg2Of 3a,in
R7556 T14955 T14954 arg1Of 3a,Fig.
R7557 T14955 T14956 arg1Of 3a,","
R7558 T14957 T14956 arg2Of 3b,","
R7559 T14960 T14959 arg1Of intensity,the
R7560 T14960 T14961 arg1Of intensity,of
R7561 T14960 T14964 arg1Of intensity,on
R7562 T14960 T14968 arg1Of intensity,was
R7563 T14960 T14970 arg2Of intensity,increased
R7564 T14963 T14961 arg2Of expression,of
R7565 T14963 T14962 arg1Of expression,IL-10R1
R7566 T14967 T14964 arg2Of cells,on
R7567 T14967 T14965 arg1Of cells,CD4+
R7568 T14967 T14966 arg1Of cells,T
R7569 T14970 T14951 arg1Of increased,As
R7570 T14970 T14958 arg1Of increased,","
R7571 T14970 T14968 arg2Of increased,was
R7572 T14970 T14969 arg1Of increased,significantly
R7573 T14970 T14971 arg1Of increased,in
R7574 T14970 T14974 arg1Of increased,compared
R7575 T14973 T14971 arg2Of patients,in
R7576 T14973 T14972 arg1Of patients,RA
R7577 T14975 T14974 arg2Of with,compared
R7578 T14975 T14976 arg1Of with,in
R7579 T14977 T14976 arg2Of healthy,in
R7580 T14978 T14975 arg2Of controls,with
R7581 T14980 T14979 arg1Of results,These
R7582 T14980 T14981 arg1Of results,suggest
R7583 T14987 T14983 arg1Of pathway,the
R7584 T14987 T14984 arg1Of pathway,intracellular
R7585 T14987 T14985 arg1Of pathway,signal
R7586 T14987 T14986 arg1Of pathway,transduction
R7587 T14987 T14988 arg1Of pathway,of
R7588 T14987 T14990 arg1Of pathway,may
R7589 T14987 T14991 arg1Of pathway,be
R7590 T14987 T14992 arg2Of pathway,impaired
R7591 T14989 T14988 arg2Of IL-10,of
R7592 T14992 T14981 arg2Of impaired,suggest
R7593 T14992 T14982 arg1Of impaired,that
R7594 T14992 T14990 arg2Of impaired,may
R7595 T14992 T14991 arg2Of impaired,be
R7596 T14992 T14993 arg1Of impaired,in
R7597 T14996 T14993 arg2Of cells,in
R7598 T14996 T14994 arg1Of cells,CD4+
R7599 T14996 T14995 arg1Of cells,T
R7600 T14996 T14997 arg1Of cells,of
R7601 T14999 T14997 arg2Of RA,of
R7602 T14999 T14998 arg1Of RA,active
R8001 T16197 T16194 arg1Of phosphorylation,Defective
R8002 T16197 T16195 arg1Of phosphorylation,IL-10-mediated
R8003 T16197 T16196 arg1Of phosphorylation,STAT3
R8004 T16197 T16198 arg1Of phosphorylation,in
R8005 T16202 T16198 arg2Of cells,in
R8006 T16202 T16199 arg1Of cells,RA
R8007 T16202 T16200 arg1Of cells,CD4+
R8008 T16202 T16201 arg1Of cells,T
R8009 T16204 T16203 arg1Of interaction,The
R8010 T16204 T16205 arg1Of interaction,of
R8011 T16204 T16207 arg1Of interaction,with
R8012 T16204 T16209 arg1Of interaction,induces
R8013 T16206 T16205 arg2Of IL-10R,of
R8014 T16208 T16207 arg2Of IL-10,with
R8015 T16211 T16210 arg1Of phosphorylation,tyrosine
R8016 T16211 T16212 arg1Of phosphorylation,and
R8017 T16212 T16209 arg2Of and,induces
R8018 T16212 T16214 arg1Of and,of
R8019 T16213 T16212 arg2Of activation,and
R8020 T16218 T16215 arg1Of factors,the
R8021 T16218 T16216 arg1Of factors,latent
R8022 T16218 T16217 arg1Of factors,transcription
R8023 T16219 T16218 arg1Of STAT1,factors
R8024 T16219 T16220 arg1Of STAT1,and
R8025 T16220 T16214 arg2Of and,of
R8026 T16221 T16220 arg2Of STAT3,and
R8027 T16221 T16222 arg1Of STAT3,[
R8028 T16223 T16222 arg2Of 3,[
R8029 T16224 T16222 arg3Of ],[
R8030 T16227 T16225 arg1Of mice,Macrophage-specific
R8031 T16227 T16226 arg1Of mice,STAT3-deficient
R8032 T16227 T16228 arg1Of mice,demonstrated
R8033 T16230 T16231 arg1Of STAT3,plays
R8034 T16231 T16228 arg2Of plays,demonstrated
R8035 T16231 T16229 arg1Of plays,that
R8036 T16234 T16231 arg2Of role,plays
R8037 T16234 T16232 arg1Of role,a
R8038 T16234 T16233 arg1Of role,dominant
R8039 T16234 T16235 arg1Of role,in
R8040 T16234 T16242 arg1Of role,","
R8041 T16234 T16243 arg1Of role,which
R8042 T16234 T16244 arg1Of role,has
R8043 T16234 T16246 arg1Of role,been
R8044 T16234 T16247 arg2Of role,confirmed
R8045 T16238 T16235 arg2Of responses,in
R8046 T16238 T16236 arg1Of responses,IL-10-mediated
R8047 T16238 T16237 arg1Of responses,anti-inflammatory
R8048 T16238 T16239 arg1Of responses,[
R8049 T16240 T16239 arg2Of 5,[
R8050 T16241 T16239 arg3Of ],[
R8051 T16247 T16244 arg2Of confirmed,has
R8052 T16247 T16245 arg1Of confirmed,recently
R8053 T16247 T16246 arg2Of confirmed,been
R8054 T16247 T16248 arg1Of confirmed,in
R8055 T16250 T16248 arg2Of macrophages,in
R8056 T16250 T16249 arg1Of macrophages,human
R8057 T16252 T16247 arg1Of studies,confirmed
R8058 T16252 T16251 arg2Of studies,by
R8059 T16252 T16253 arg1Of studies,of
R8060 T16256 T16253 arg2Of overexpression,of
R8061 T16256 T16254 arg1Of overexpression,dominant-negative
R8062 T16256 T16255 arg1Of overexpression,STAT3
R8063 T16256 T16257 arg1Of overexpression,[
R8064 T16258 T16257 arg2Of 30,[
R8065 T16259 T16257 arg3Of ],[
R8066 T16261 T16260 arg1Of induction,The
R8067 T16261 T16262 arg1Of induction,of
R8068 T16261 T16267 arg1Of induction,by
R8069 T16261 T16269 arg1Of induction,in
R8070 T16261 T16279 arg1Of induction,from
R8071 T16261 T16282 arg1Of induction,was
R8072 T16261 T16283 arg2Of induction,examined
R8073 T16263 T16264 arg1Of STAT1,and
R8074 T16265 T16264 arg2Of STAT3,and
R8075 T16266 T16262 arg2Of phosphorylation,of
R8076 T16266 T16263 arg1Of phosphorylation,STAT1
R8077 T16266 T16265 arg1Of phosphorylation,STAT3
R8078 T16268 T16267 arg2Of IL-10,by
R8079 T16269 T16278 arg1Of in,and
R8080 T16273 T16269 arg2Of cells,in
R8081 T16273 T16270 arg1Of cells,PB
R8082 T16273 T16271 arg1Of cells,CD4+
R8083 T16273 T16272 arg1Of cells,T
R8084 T16273 T16274 arg1Of cells,from
R8085 T16277 T16274 arg2Of patients,from
R8086 T16277 T16275 arg1Of patients,active
R8087 T16277 T16276 arg1Of patients,RA
R8088 T16279 T16278 arg2Of from,and
R8089 T16281 T16279 arg2Of controls,from
R8090 T16281 T16280 arg1Of controls,healthy
R8091 T16283 T16282 arg2Of examined,was
R8092 T16284 T16283 arg3Of using,examined
R8093 T16286 T16284 arg2Of blotting,using
R8094 T16286 T16285 arg1Of blotting,western
R8095 T16288 T16287 arg1Of phosphorylation,STAT3
R8096 T16288 T16289 arg1Of phosphorylation,was
R8097 T16288 T16291 arg2Of phosphorylation,induced
R8098 T16291 T16289 arg2Of induced,was
R8099 T16291 T16290 arg1Of induced,dose-dependently
R8100 T16291 T16292 arg1Of induced,after
R8101 T16294 T16292 arg2Of activation,after
R8102 T16294 T16293 arg1Of activation,IL-10
R8103 T16294 T16295 arg1Of activation,for
R8104 T16297 T16295 arg2Of min,for
R8105 T16297 T16296 arg1Of min,20
R8106 T16297 T16298 arg1Of min,in
R8107 T16302 T16298 arg2Of cells,in
R8108 T16302 T16299 arg1Of cells,normal
R8109 T16302 T16300 arg1Of cells,CD4+
R8110 T16302 T16301 arg1Of cells,T
R8111 T16302 T16303 arg1Of cells,(
R8112 T16305 T16303 arg2Of 4a,(
R8113 T16305 T16304 arg1Of 4a,Fig.
R8114 T16305 T16306 arg1Of 4a,","
R8115 T16307 T16306 arg2Of 4b,","
R8116 T16308 T16303 arg3Of ),(
R8117 T16310 T16309 arg2Of contrast,In
R8118 T16312 T16313 arg1Of STAT3,was
R8119 T16312 T16314 arg2Of STAT3,phosphorylated
R8120 T16314 T16309 arg1Of phosphorylated,In
R8121 T16314 T16311 arg1Of phosphorylated,","
R8122 T16314 T16313 arg2Of phosphorylated,was
R8123 T16314 T16315 arg1Of phosphorylated,in
R8124 T16314 T16324 arg1Of phosphorylated,and
R8125 T16317 T16316 arg1Of isolated,freshly
R8126 T16320 T16315 arg2Of cells,in
R8127 T16320 T16317 arg1Of cells,isolated
R8128 T16320 T16318 arg1Of cells,PB
R8129 T16320 T16319 arg1Of cells,CD4+
R8130 T16320 T16321 arg1Of cells,from
R8131 T16323 T16321 arg2Of patients,from
R8132 T16323 T16322 arg1Of patients,RA
R8133 T16327 T16325 arg1Of phosphorylation,this
R8134 T16327 T16326 arg1Of phosphorylation,STAT3
R8135 T16327 T16328 arg1Of phosphorylation,was
R8136 T16327 T16329 arg1Of phosphorylation,detectable
R8137 T16328 T16324 arg2Of was,and
R8138 T16328 T16330 arg1Of was,for
R8139 T16329 T16328 arg2Of detectable,was
R8140 T16333 T16331 arg1Of 6,up
R8141 T16333 T16332 arg1Of 6,to
R8142 T16334 T16330 arg2Of hours,for
R8143 T16334 T16333 arg1Of hours,6
R8144 T16336 T16335 arg1Of phosphorylation,STAT3
R8145 T16336 T16337 arg1Of phosphorylation,was
R8146 T16336 T16338 arg2Of phosphorylation,augmented
R8147 T16336 T16341 arg1Of phosphorylation,activated
R8148 T16338 T16337 arg2Of augmented,was
R8149 T16338 T16339 arg1Of augmented,only
R8150 T16338 T16340 arg1Of augmented,when
R8151 T16341 T16340 arg2Of activated,when
R8152 T16341 T16342 arg1Of activated,by
R8153 T16346 T16343 arg1Of 10,as
R8154 T16346 T16344 arg1Of 10,much
R8155 T16346 T16345 arg1Of 10,as
R8156 T16346 T16347 arg1Of 10,ng/ml
R8157 T16348 T16342 arg2Of IL-10,by
R8158 T16348 T16346 arg1Of IL-10,10
R8159 T16352 T16350 arg1Of phosphorylation,sustained
R8160 T16352 T16351 arg1Of phosphorylation,STAT3
R8161 T16352 T16353 arg1Of phosphorylation,and
R8162 T16353 T16349 arg1Of and,Both
R8163 T16353 T16358 arg1Of and,were
R8164 T16353 T16359 arg2Of and,found
R8165 T16357 T16353 arg2Of phosphorylation,and
R8166 T16357 T16354 arg1Of phosphorylation,defective
R8167 T16357 T16355 arg1Of phosphorylation,IL-10-induced
R8168 T16357 T16356 arg1Of phosphorylation,STAT3
R8169 T16359 T16358 arg2Of found,were
R8170 T16359 T16360 arg1Of found,in
R8171 T16365 T16360 arg2Of cells,in
R8172 T16365 T16361 arg1Of cells,RA
R8173 T16365 T16362 arg1Of cells,ST
R8174 T16365 T16363 arg1Of cells,CD4+
R8175 T16365 T16364 arg1Of cells,T
R8176 T16365 T16366 arg1Of cells,(
R8177 T16368 T16366 arg2Of 4c,(
R8178 T16368 T16367 arg1Of 4c,Fig.
R8179 T16369 T16366 arg3Of ),(
R8180 T16373 T16370 arg2Of hand,On
R8181 T16373 T16371 arg1Of hand,the
R8182 T16373 T16372 arg1Of hand,other
R8183 T16377 T16375 arg1Of phosphorylation,IL-10-induced
R8184 T16377 T16376 arg1Of phosphorylation,STAT1
R8185 T16377 T16378 arg1Of phosphorylation,was
R8186 T16377 T16380 arg2Of phosphorylation,detected
R8187 T16380 T16370 arg1Of detected,On
R8188 T16380 T16374 arg1Of detected,","
R8189 T16380 T16378 arg2Of detected,was
R8190 T16380 T16379 arg1Of detected,not
R8191 T16380 T16381 arg1Of detected,in
R8192 T16386 T16382 arg1Of cells,either
R8193 T16386 T16383 arg1Of cells,RA
R8194 T16386 T16384 arg1Of cells,CD4+
R8195 T16386 T16385 arg1Of cells,T
R8196 T16386 T16387 arg1Of cells,or
R8197 T16387 T16381 arg2Of or,in
R8198 T16391 T16387 arg2Of cells,or
R8199 T16391 T16388 arg1Of cells,normal
R8200 T16391 T16389 arg1Of cells,CD4+
R8201 T16391 T16390 arg1Of cells,T
R8202 T16391 T16392 arg1Of cells,(
R8203 T16394 T16392 arg2Of 4a,(
R8204 T16394 T16393 arg1Of 4a,Fig.
R8205 T16395 T16392 arg3Of ),(
R8206 T16397 T16396 arg1Of results,These
R8207 T16397 T16398 arg1Of results,indicate
R8208 T16398 T16411 arg1Of indicate,and
R8209 T16400 T16401 arg1Of STAT3,is
R8210 T16401 T16398 arg2Of is,indicate
R8211 T16401 T16399 arg1Of is,that
R8212 T16405 T16401 arg2Of STAT,is
R8213 T16405 T16402 arg1Of STAT,the
R8214 T16405 T16403 arg1Of STAT,major
R8215 T16405 T16404 arg1Of STAT,IL-10-activated
R8216 T16405 T16406 arg1Of STAT,in
R8217 T16409 T16406 arg2Of cells,in
R8218 T16409 T16407 arg1Of cells,CD4+
R8219 T16409 T16408 arg1Of cells,T
R8220 T16411 T16410 arg1Of and,","
R8221 T16414 T16412 arg1Of activation,IL-10-induced
R8222 T16414 T16413 arg1Of activation,STAT3
R8223 T16414 T16415 arg1Of activation,may
R8224 T16414 T16416 arg1Of activation,be
R8225 T16414 T16417 arg2Of activation,diminished
R8226 T16417 T16411 arg2Of diminished,and
R8227 T16417 T16415 arg2Of diminished,may
R8228 T16417 T16416 arg2Of diminished,be
R8229 T16417 T16418 arg1Of diminished,in
R8230 T16417 T16421 arg1Of diminished,","
R8231 T16417 T16422 arg1Of diminished,in
R8232 T16420 T16418 arg2Of RA,in
R8233 T16420 T16419 arg1Of RA,active
R8234 T16423 T16422 arg2Of association,in
R8235 T16423 T16424 arg1Of association,with
R8236 T16427 T16424 arg2Of phosphorylation,with
R8237 T16427 T16425 arg1Of phosphorylation,sustained
R8238 T16427 T16426 arg1Of phosphorylation,STAT3
R8964 T18497 T18495 arg1Of phosphorylation,IL-6-mediated
R8965 T18497 T18496 arg1Of phosphorylation,STAT3
R8966 T18497 T18498 arg1Of phosphorylation,and
R8967 T18498 T18503 arg1Of and,in
R8968 T18499 T18498 arg2Of inhibition,and
R8969 T18499 T18500 arg1Of inhibition,of
R8970 T18502 T18500 arg2Of effect,of
R8971 T18502 T18501 arg1Of effect,IL-10
R8972 T18507 T18503 arg2Of cells,in
R8973 T18507 T18504 arg1Of cells,normal
R8974 T18507 T18505 arg1Of cells,CD4+
R8975 T18507 T18506 arg1Of cells,T
R8976 T18508 T18509 arg1Of STAT3,is
R8977 T18508 T18510 arg2Of STAT3,activated
R8978 T18510 T18509 arg2Of activated,is
R8979 T18510 T18546 arg1Of activated,","
R8980 T18510 T18547 arg1Of activated,in
R8981 T18510 T18555 arg1Of activated,but
R8982 T18513 T18512 arg1Of cytokines,many
R8983 T18513 T18514 arg1Of cytokines,and
R8984 T18514 T18510 arg1Of and,activated
R8985 T18514 T18511 arg2Of and,by
R8986 T18514 T18518 arg1Of and,as
R8987 T18516 T18514 arg2Of factors,and
R8988 T18516 T18515 arg1Of factors,growth
R8989 T18518 T18517 arg1Of as,such
R8990 T18521 T18520 arg1Of family,IL-6
R8991 T18521 T18522 arg1Of family,of
R8992 T18521 T18542 arg1Of family,and
R8993 T18523 T18524 arg1Of cytokines,(
R8994 T18523 T18537 arg1Of cytokines,","
R8995 T18525 T18526 arg1Of IL-6,","
R8996 T18526 T18528 arg1Of ",",","
R8997 T18527 T18526 arg2Of IL-11,","
R8998 T18528 T18533 arg1Of ",",and
R8999 T18531 T18528 arg2Of factor,","
R9000 T18531 T18529 arg1Of factor,leukemia
R9001 T18531 T18530 arg1Of factor,inhibitory
R9002 T18533 T18524 arg2Of and,(
R9003 T18533 T18532 arg1Of and,","
R9004 T18535 T18533 arg2Of M,and
R9005 T18535 T18534 arg1Of M,oncostatin
R9006 T18536 T18524 arg3Of ),(
R9007 T18537 T18522 arg2Of ",",of
R9008 T18540 T18537 arg2Of factor,","
R9009 T18540 T18538 arg1Of factor,platelet-derived
R9010 T18540 T18539 arg1Of factor,growth
R9011 T18542 T18518 arg2Of and,as
R9012 T18542 T18519 arg1Of and,the
R9013 T18542 T18541 arg1Of and,","
R9014 T18545 T18542 arg2Of factor,and
R9015 T18545 T18543 arg1Of factor,epidermal
R9016 T18545 T18544 arg1Of factor,growth
R9017 T18548 T18547 arg2Of addition,in
R9018 T18548 T18549 arg1Of addition,to
R9019 T18550 T18549 arg2Of IL-10,to
R9020 T18550 T18551 arg1Of IL-10,[
R9021 T18552 T18551 arg2Of 4,[
R9022 T18553 T18551 arg3Of ],[
R9023 T18555 T18554 arg1Of but,","
R9024 T18557 T18556 arg1Of studies,previous
R9025 T18557 T18558 arg1Of studies,have
R9026 T18557 T18559 arg1Of studies,demonstrated
R9027 T18559 T18555 arg2Of demonstrated,but
R9028 T18559 T18558 arg2Of demonstrated,have
R9029 T18561 T18562 arg1Of IL-6,is
R9030 T18562 T18559 arg2Of is,demonstrated
R9031 T18562 T18560 arg1Of is,that
R9032 T18565 T18562 arg2Of factor,is
R9033 T18565 T18563 arg1Of factor,the
R9034 T18565 T18564 arg1Of factor,major
R9035 T18565 T18566 arg1Of factor,in
R9036 T18565 T18570 arg1Of factor,that
R9037 T18565 T18571 arg1Of factor,induces
R9038 T18569 T18566 arg2Of fluid,in
R9039 T18569 T18567 arg1Of fluid,RA
R9040 T18569 T18568 arg1Of fluid,synovial
R9041 T18571 T18579 arg1Of induces,[
R9042 T18573 T18571 arg2Of activation,induces
R9043 T18573 T18572 arg1Of activation,constitutive
R9044 T18573 T18574 arg1Of activation,of
R9045 T18573 T18576 arg1Of activation,in
R9046 T18575 T18574 arg2Of STAT3,of
R9047 T18578 T18576 arg2Of cells,in
R9048 T18578 T18577 arg1Of cells,mononuclear
R9049 T18580 T18579 arg2Of 31,[
R9050 T18581 T18579 arg3Of ],[
R9051 T18583 T18584 arg1Of IL-6,is
R9052 T18583 T18586 arg1Of IL-6,abundant
R9053 T18584 T18582 arg2Of is,Since
R9054 T18584 T18585 arg1Of is,also
R9055 T18584 T18587 arg1Of is,in
R9056 T18586 T18584 arg2Of abundant,is
R9057 T18588 T18587 arg2Of sera,in
R9058 T18588 T18589 arg1Of sera,of
R9059 T18592 T18589 arg2Of patients,of
R9060 T18592 T18590 arg1Of patients,active
R9061 T18592 T18591 arg1Of patients,RA
R9062 T18592 T18593 arg1Of patients,","
R9063 T18592 T18595 arg2Of patients,detected
R9064 T18595 T18594 arg1Of detected,frequently
R9065 T18595 T18596 arg1Of detected,at
R9066 T18598 T18597 arg1Of 1,>
R9067 T18599 T18596 arg2Of ng/ml,at
R9068 T18599 T18598 arg1Of ng/ml,1
R9069 T18599 T18600 arg1Of ng/ml,[
R9070 T18601 T18600 arg2Of 27,[
R9071 T18602 T18600 arg3Of ],[
R9072 T18604 T18605 arg1Of we,examined
R9073 T18605 T18582 arg1Of examined,Since
R9074 T18605 T18603 arg1Of examined,","
R9075 T18608 T18607 arg1Of exposure,persistent
R9076 T18608 T18609 arg1Of exposure,of
R9077 T18608 T18613 arg1Of exposure,to
R9078 T18608 T18618 arg1Of exposure,in
R9079 T18608 T18622 arg1Of exposure,was
R9080 T18608 T18623 arg1Of exposure,responsible
R9081 T18612 T18609 arg2Of cells,of
R9082 T18612 T18610 arg1Of cells,CD4+
R9083 T18612 T18611 arg1Of cells,T
R9084 T18615 T18613 arg2Of concentrations,to
R9085 T18615 T18614 arg1Of concentrations,high
R9086 T18615 T18616 arg1Of concentrations,of
R9087 T18617 T18616 arg2Of IL-6,of
R9088 T18621 T18618 arg2Of circulation,in
R9089 T18621 T18619 arg1Of circulation,the
R9090 T18621 T18620 arg1Of circulation,blood
R9091 T18622 T18605 arg2Of was,examined
R9092 T18622 T18606 arg1Of was,whether
R9093 T18623 T18622 arg2Of responsible,was
R9094 T18623 T18624 arg1Of responsible,for
R9095 T18628 T18626 arg1Of activation,sustained
R9096 T18628 T18627 arg1Of activation,STAT3
R9097 T18628 T18629 arg1Of activation,and
R9098 T18629 T18624 arg2Of and,for
R9099 T18629 T18625 arg1Of and,their
R9100 T18629 T18634 arg1Of and,in
R9101 T18630 T18629 arg2Of resistance,and
R9102 T18630 T18631 arg1Of resistance,to
R9103 T18633 T18631 arg2Of inhibition,to
R9104 T18633 T18632 arg1Of inhibition,IL-10
R9105 T18636 T18634 arg2Of RA,in
R9106 T18636 T18635 arg1Of RA,active
R9107 T18638 T18639 arg1Of STAT1,and
R9108 T18640 T18639 arg2Of STAT3,and
R9109 T18641 T18637 arg1Of phosphorylation,Both
R9110 T18641 T18638 arg1Of phosphorylation,STAT1
R9111 T18641 T18640 arg1Of phosphorylation,STAT3
R9112 T18641 T18642 arg1Of phosphorylation,was
R9113 T18641 T18643 arg2Of phosphorylation,activated
R9114 T18643 T18642 arg2Of activated,was
R9115 T18643 T18646 arg1Of activated,in
R9116 T18643 T18656 arg1Of activated,","
R9117 T18643 T18657 arg1Of activated,in
R9118 T18645 T18643 arg1Of IL-6,activated
R9119 T18645 T18644 arg2Of IL-6,by
R9120 T18650 T18646 arg2Of cells,in
R9121 T18650 T18647 arg1Of cells,normal
R9122 T18650 T18648 arg1Of cells,CD4+
R9123 T18650 T18649 arg1Of cells,T
R9124 T18650 T18651 arg1Of cells,(
R9125 T18652 T18651 arg2Of data,(
R9126 T18652 T18654 arg2Of data,shown
R9127 T18654 T18653 arg1Of shown,not
R9128 T18655 T18651 arg3Of ),(
R9129 T18658 T18657 arg2Of agreement,in
R9130 T18658 T18659 arg1Of agreement,with
R9131 T18661 T18659 arg2Of observations,with
R9132 T18661 T18660 arg1Of observations,previous
R9133 T18661 T18662 arg1Of observations,[
R9134 T18663 T18662 arg2Of 4,[
R9135 T18664 T18662 arg3Of ],[
R9136 T18668 T18665 arg1Of cells,Normal
R9137 T18668 T18666 arg1Of cells,CD4+
R9138 T18668 T18667 arg1Of cells,T
R9139 T18668 T18669 arg1Of cells,were
R9140 T18668 T18671 arg2Of cells,incubated
R9141 T18668 T18687 arg1Of cells,neutralizing
R9142 T18671 T18670 arg1Of incubated,thus
R9143 T18671 T18672 arg1Of incubated,for
R9144 T18671 T18675 arg1Of incubated,with
R9145 T18671 T18686 arg1Of incubated,and
R9146 T18674 T18672 arg2Of min,for
R9147 T18674 T18673 arg1Of min,20
R9148 T18677 T18675 arg2Of medium,with
R9149 T18677 T18676 arg1Of medium,culture
R9150 T18677 T18678 arg1Of medium,containing
R9151 T18679 T18680 arg1Of 30,%
R9152 T18681 T18678 arg2Of serum,containing
R9153 T18681 T18679 arg1Of serum,30
R9154 T18681 T18682 arg1Of serum,from
R9155 T18685 T18682 arg2Of patients,from
R9156 T18685 T18683 arg1Of patients,active
R9157 T18685 T18684 arg1Of patients,RA
R9158 T18686 T18669 arg2Of and,were
R9159 T18686 T18694 arg1Of and,and
R9160 T18687 T18686 arg2Of neutralizing,and
R9161 T18689 T18690 arg1Of antibody,or
R9162 T18691 T18690 arg2Of control,or
R9163 T18692 T18687 arg2Of antibody,neutralizing
R9164 T18692 T18688 arg1Of antibody,anti-IL-6
R9165 T18692 T18689 arg1Of antibody,antibody
R9166 T18692 T18691 arg1Of antibody,control
R9167 T18694 T18693 arg1Of and,","
R9168 T18696 T18695 arg1Of phosphorylation,STAT
R9169 T18696 T18697 arg1Of phosphorylation,was
R9170 T18696 T18698 arg2Of phosphorylation,examined
R9171 T18698 T18694 arg2Of examined,and
R9172 T18698 T18697 arg2Of examined,was
R9173 T18702 T18698 arg1Of analysis,examined
R9174 T18702 T18699 arg2Of analysis,by
R9175 T18702 T18700 arg1Of analysis,western
R9176 T18702 T18701 arg1Of analysis,blot
R9177 T18704 T18703 arg1Of serum,RA
R9178 T18704 T18705 arg1Of serum,was
R9179 T18704 T18706 arg1Of serum,able
R9180 T18704 T18708 arg1Of serum,induce
R9181 T18705 T18717 arg1Of was,and
R9182 T18706 T18705 arg2Of able,was
R9183 T18708 T18706 arg2Of induce,able
R9184 T18708 T18707 arg1Of induce,to
R9185 T18710 T18708 arg2Of phosphorylation,induce
R9186 T18710 T18709 arg1Of phosphorylation,tyrosine
R9187 T18710 T18711 arg1Of phosphorylation,of
R9188 T18712 T18713 arg1Of STAT3,but
R9189 T18713 T18711 arg2Of but,of
R9190 T18713 T18714 arg1Of but,not
R9191 T18715 T18713 arg2Of STAT1,but
R9192 T18717 T18716 arg1Of and,","
R9193 T18720 T18718 arg1Of activation,this
R9194 T18720 T18719 arg1Of activation,STAT3
R9195 T18720 T18721 arg1Of activation,was
R9196 T18720 T18723 arg2Of activation,abolished
R9197 T18723 T18717 arg2Of abolished,and
R9198 T18723 T18721 arg2Of abolished,was
R9199 T18723 T18722 arg1Of abolished,mostly
R9200 T18725 T18723 arg1Of neutralization,abolished
R9201 T18725 T18724 arg2Of neutralization,by
R9202 T18725 T18726 arg1Of neutralization,of
R9203 T18728 T18726 arg2Of activity,of
R9204 T18728 T18727 arg1Of activity,IL-6
R9205 T18728 T18729 arg1Of activity,(
R9206 T18731 T18729 arg2Of 5a,(
R9207 T18731 T18730 arg1Of 5a,Fig.
R9208 T18732 T18729 arg3Of ),(
R9209 T18734 T18733 arg1Of results,These
R9210 T18734 T18735 arg1Of results,indicate
R9211 T18737 T18738 arg1Of IL-6,is
R9212 T18738 T18735 arg2Of is,indicate
R9213 T18738 T18736 arg1Of is,that
R9214 T18742 T18738 arg2Of factor,is
R9215 T18742 T18739 arg1Of factor,the
R9216 T18742 T18740 arg1Of factor,dominant
R9217 T18742 T18741 arg1Of factor,STAT3-activating
R9218 T18742 T18743 arg2Of factor,contained
R9219 T18743 T18744 arg1Of contained,in
R9220 T18745 T18744 arg2Of sera,in
R9221 T18745 T18746 arg1Of sera,of
R9222 T18749 T18746 arg2Of patients,of
R9223 T18749 T18747 arg1Of patients,active
R9224 T18749 T18748 arg1Of patients,RA
R9225 T18751 T18750 arg1Of lack,The
R9226 T18751 T18752 arg1Of lack,of
R9227 T18751 T18755 arg1Of lack,by
R9228 T18751 T18758 arg1Of lack,suggests
R9229 T18754 T18752 arg2Of activation,of
R9230 T18754 T18753 arg1Of activation,STAT1
R9231 T18757 T18755 arg2Of serum,by
R9232 T18757 T18756 arg1Of serum,RA
R9233 T18761 T18760 arg1Of higher,much
R9234 T18762 T18761 arg1Of concentrations,higher
R9235 T18762 T18763 arg1Of concentrations,of
R9236 T18762 T18765 arg1Of concentrations,may
R9237 T18762 T18766 arg1Of concentrations,be
R9238 T18762 T18767 arg2Of concentrations,required
R9239 T18764 T18763 arg2Of IL-6,of
R9240 T18767 T18759 arg1Of required,that
R9241 T18767 T18765 arg2Of required,may
R9242 T18767 T18766 arg2Of required,be
R9243 T18767 T18768 arg1Of required,for
R9244 T18767 T18771 arg1Of required,as
R9245 T18767 T18777 arg1Of required,or
R9246 T18770 T18768 arg2Of activation,for
R9247 T18770 T18769 arg1Of activation,STAT1
R9248 T18772 T18771 arg2Of compared,as
R9249 T18772 T18773 arg1Of compared,with
R9250 T18775 T18773 arg2Of activation,with
R9251 T18775 T18774 arg1Of activation,STAT3
R9252 T18777 T18758 arg2Of or,suggests
R9253 T18777 T18776 arg1Of or,","
R9254 T18778 T18777 arg2Of that,or
R9255 T18779 T18780 arg1Of inhibitors,of
R9256 T18779 T18783 arg1Of inhibitors,may
R9257 T18779 T18784 arg1Of inhibitors,be
R9258 T18779 T18785 arg1Of inhibitors,present
R9259 T18782 T18780 arg2Of signaling,of
R9260 T18782 T18781 arg1Of signaling,STAT1
R9261 T18784 T18778 arg2Of be,that
R9262 T18784 T18783 arg2Of be,may
R9263 T18785 T18784 arg2Of present,be
R9264 T18785 T18786 arg1Of present,in
R9265 T18788 T18786 arg2Of serum,in
R9266 T18788 T18787 arg1Of serum,RA
R9267 T18789 T18791 arg1Of We,examined
R9268 T18791 T18790 arg1Of examined,next
R9269 T18793 T18794 arg1Of IL-6,could
R9270 T18793 T18795 arg1Of IL-6,suppress
R9271 T18795 T18791 arg2Of suppress,examined
R9272 T18795 T18792 arg1Of suppress,whether
R9273 T18795 T18794 arg2Of suppress,could
R9274 T18797 T18795 arg2Of effect,suppress
R9275 T18797 T18796 arg1Of effect,the
R9276 T18797 T18798 arg1Of effect,of
R9277 T18797 T18800 modOf effect,to
R9278 T18799 T18798 arg2Of IL-10,of
R9279 T18801 T18800 arg1Of inhibit,to
R9280 T18801 T18804 arg1Of inhibit,by
R9281 T18803 T18801 arg2Of production,inhibit
R9282 T18803 T18802 arg1Of production,IFN-γ
R9283 T18807 T18804 arg2Of cells,by
R9284 T18807 T18805 arg1Of cells,CD4+
R9285 T18807 T18806 arg1Of cells,T
R9286 T18809 T18808 arg2Of preincubation,After
R9287 T18809 T18810 arg1Of preincubation,with
R9288 T18809 T18812 arg1Of preincubation,without
R9289 T18809 T18816 arg1Of preincubation,for
R9290 T18810 T18811 arg1Of with,or
R9291 T18812 T18811 arg2Of without,or
R9292 T18813 T18814 arg1Of 10,ng/ml
R9293 T18815 T18810 arg2Of IL-6,with
R9294 T18815 T18812 arg2Of IL-6,without
R9295 T18815 T18813 arg1Of IL-6,10
R9296 T18818 T18816 arg2Of hours,for
R9297 T18818 T18817 arg1Of hours,36
R9298 T18823 T18820 arg1Of cells,normal
R9299 T18823 T18821 arg1Of cells,CD4+
R9300 T18823 T18822 arg1Of cells,T
R9301 T18823 T18824 arg1Of cells,were
R9302 T18823 T18825 arg2Of cells,stimulated
R9303 T18825 T18824 arg2Of stimulated,were
R9304 T18825 T18844 arg1Of stimulated,and
R9305 T18827 T18828 arg1Of CD3,and
R9306 T18828 T18825 arg1Of and,stimulated
R9307 T18828 T18826 arg2Of and,by
R9308 T18828 T18831 arg1Of and,in
R9309 T18830 T18828 arg2Of costimulation,and
R9310 T18830 T18829 arg1Of costimulation,CD28
R9311 T18833 T18834 arg1Of presence,or
R9312 T18834 T18831 arg2Of or,in
R9313 T18834 T18832 arg1Of or,the
R9314 T18834 T18836 arg1Of or,of
R9315 T18835 T18834 arg2Of absence,or
R9316 T18837 T18838 arg1Of 1,ng/ml
R9317 T18839 T18836 arg2Of IL-10,of
R9318 T18839 T18837 arg1Of IL-10,1
R9319 T18839 T18840 arg1Of IL-10,for
R9320 T18842 T18840 arg2Of hours,for
R9321 T18842 T18841 arg1Of hours,36
R9322 T18844 T18808 arg1Of and,After
R9323 T18844 T18819 arg1Of and,","
R9324 T18844 T18843 arg1Of and,","
R9325 T18847 T18845 arg1Of production,the
R9326 T18847 T18846 arg1Of production,IFN-γ
R9327 T18847 T18848 arg1Of production,was
R9328 T18847 T18849 arg2Of production,measured
R9329 T18849 T18844 arg2Of measured,and
R9330 T18849 T18848 arg2Of measured,was
R9331 T18851 T18849 arg1Of ELISA,measured
R9332 T18851 T18850 arg2Of ELISA,by
R9333 T18853 T18852 arg1Of pretreatment,IL-6
R9334 T18853 T18854 arg1Of pretreatment,of
R9335 T18853 T18857 arg1Of pretreatment,reduced
R9336 T18856 T18854 arg2Of cells,of
R9337 T18856 T18855 arg1Of cells,normal
R9338 T18857 T18867 arg1Of reduced,","
R9339 T18857 T18868 modOf reduced,indicating
R9340 T18859 T18857 arg2Of inhibition,reduced
R9341 T18859 T18858 arg1Of inhibition,IL-10-mediated
R9342 T18859 T18860 arg1Of inhibition,of
R9343 T18862 T18860 arg2Of production,of
R9344 T18862 T18861 arg1Of production,IFN-γ
R9345 T18862 T18863 arg1Of production,(
R9346 T18865 T18863 arg2Of 5b,(
R9347 T18865 T18864 arg1Of 5b,Fig.
R9348 T18866 T18863 arg3Of ),(
R9349 T18871 T18870 arg1Of concentrations,high
R9350 T18871 T18872 arg1Of concentrations,of
R9351 T18871 T18874 arg1Of concentrations,could
R9352 T18871 T18875 arg1Of concentrations,modulate
R9353 T18873 T18872 arg2Of IL-6,of
R9354 T18875 T18868 arg2Of modulate,indicating
R9355 T18875 T18869 arg1Of modulate,that
R9356 T18875 T18874 arg2Of modulate,could
R9357 T18877 T18875 arg2Of responsiveness,modulate
R9358 T18877 T18876 arg1Of responsiveness,T-cell
R9359 T18877 T18878 arg1Of responsiveness,to
R9360 T18879 T18878 arg2Of IL-10,to
R9361 T18880 T18881 arg1Of Taken,together
R9362 T18884 T18883 arg1Of findings,these
R9363 T18884 T18885 arg1Of findings,suggest
R9364 T18885 T18880 modOf suggest,Taken
R9365 T18885 T18882 arg1Of suggest,","
R9366 T18888 T18887 arg1Of exposure,persistent
R9367 T18888 T18889 arg1Of exposure,to
R9368 T18888 T18892 arg1Of exposure,may
R9369 T18888 T18893 arg1Of exposure,have
R9370 T18891 T18889 arg2Of IL-6,to
R9371 T18891 T18890 arg1Of IL-6,serum
R9372 T18893 T18885 arg2Of have,suggest
R9373 T18893 T18886 arg1Of have,that
R9374 T18893 T18892 arg2Of have,may
R9375 T18893 T18896 arg1Of have,in
R9376 T18895 T18893 arg2Of role,have
R9377 T18895 T18894 arg1Of role,a
R9378 T18899 T18898 arg1Of induction,the
R9379 T18899 T18900 arg1Of induction,of
R9380 T18899 T18903 arg1Of induction,and
R9381 T18902 T18900 arg2Of activation,of
R9382 T18902 T18901 arg1Of activation,STAT3
R9383 T18903 T18896 arg2Of and,in
R9384 T18903 T18897 arg1Of and,both
R9385 T18905 T18903 arg2Of resistance,and
R9386 T18905 T18904 arg1Of resistance,the
R9387 T18905 T18906 arg1Of resistance,to
R9388 T18909 T18906 arg2Of effect,to
R9389 T18909 T18907 arg1Of effect,the
R9390 T18909 T18908 arg1Of effect,inhibitory
R9391 T18909 T18910 arg1Of effect,of
R9392 T18909 T18912 arg1Of effect,in
R9393 T18911 T18910 arg2Of IL-10,of
R9394 T18916 T18912 arg2Of cells,in
R9395 T18916 T18913 arg1Of cells,RA
R9396 T18916 T18914 arg1Of cells,CD4+
R9397 T18916 T18915 arg1Of cells,T
R10215 T20674 T20673 arg1Of expression,High
R10216 T20674 T20675 arg1Of expression,of
R10217 T20674 T20678 arg1Of expression,in
R10218 T20677 T20675 arg2Of mRNA,of
R10219 T20677 T20676 arg1Of mRNA,SOCS1
R10220 T20682 T20678 arg2Of cells,in
R10221 T20682 T20679 arg1Of cells,RA
R10222 T20682 T20680 arg1Of cells,CD4+
R10223 T20682 T20681 arg1Of cells,T
R10224 T20683 T20684 arg1Of IL-6,induces
R10225 T20687 T20684 arg2Of inhibitors,induces
R10226 T20687 T20685 arg1Of inhibitors,two
R10227 T20687 T20686 arg1Of inhibitors,potent
R10228 T20687 T20688 arg1Of inhibitors,of
R10229 T20689 T20688 arg2Of JAKs,of
R10230 T20689 T20690 arg1Of JAKs,(
R10231 T20689 T20696 arg1Of JAKs,that
R10232 T20689 T20699 arg1Of JAKs,act
R10233 T20689 T20709 arg1Of JAKs,play
R10234 T20689 T20717 arg1Of JAKs,opposing
R10235 T20691 T20692 arg1Of SOCS1,and
R10236 T20692 T20690 arg2Of and,(
R10237 T20694 T20692 arg2Of proteins,and
R10238 T20694 T20693 arg1Of proteins,SOCS3
R10239 T20695 T20690 arg3Of ),(
R10240 T20698 T20697 arg1Of only,not
R10241 T20699 T20700 arg1Of act,as
R10242 T20699 T20707 arg1Of act,but
R10243 T20701 T20700 arg2Of mediators,as
R10244 T20701 T20702 arg1Of mediators,of
R10245 T20705 T20702 arg2Of inhibition,of
R10246 T20705 T20703 arg1Of inhibition,negative
R10247 T20705 T20704 arg1Of inhibition,feedback
R10248 T20707 T20698 arg1Of but,only
R10249 T20707 T20706 arg1Of but,","
R10250 T20707 T20708 arg1Of but,also
R10251 T20709 T20707 arg2Of play,but
R10252 T20709 T20713 arg1Of play,in
R10253 T20709 T20716 arg1Of play,by
R10254 T20712 T20709 arg2Of role,play
R10255 T20712 T20710 arg1Of role,a
R10256 T20712 T20711 arg1Of role,major
R10257 T20715 T20713 arg2Of inhibition,in
R10258 T20715 T20714 arg1Of inhibition,crosstalk
R10259 T20717 T20716 arg2Of opposing,by
R10260 T20720 T20717 arg2Of pathways,opposing
R10261 T20720 T20718 arg1Of pathways,other
R10262 T20720 T20719 arg1Of pathways,cytokine-signaling
R10263 T20720 T20721 arg1Of pathways,[
R10264 T20722 T20721 arg2Of 7,[
R10265 T20723 T20721 arg3Of ],[
R10266 T20724 T20725 arg1Of SOCS3,has
R10267 T20724 T20727 arg1Of SOCS3,been
R10268 T20724 T20728 arg2Of SOCS3,shown
R10269 T20724 T20731 arg1Of SOCS3,inhibit
R10270 T20724 T20743 arg1Of SOCS3,regulating
R10271 T20728 T20725 arg2Of shown,has
R10272 T20728 T20726 arg1Of shown,recently
R10273 T20728 T20727 arg2Of shown,been
R10274 T20731 T20728 arg3Of inhibit,shown
R10275 T20731 T20729 arg1Of inhibit,to
R10276 T20731 T20730 arg1Of inhibit,specifically
R10277 T20731 T20741 arg1Of inhibit,","
R10278 T20731 T20743 modOf inhibit,regulating
R10279 T20733 T20731 arg2Of activation,inhibit
R10280 T20733 T20732 arg1Of activation,STAT3
R10281 T20733 T20734 arg2Of activation,induced
R10282 T20734 T20735 arg1Of induced,by
R10283 T20734 T20739 arg1Of induced,by
R10284 T20735 T20737 arg1Of by,but
R10285 T20736 T20735 arg2Of IL-6,by
R10286 T20739 T20737 arg2Of by,but
R10287 T20739 T20738 arg1Of by,not
R10288 T20740 T20739 arg2Of IL-10,by
R10289 T20743 T20742 arg1Of regulating,thereby
R10290 T20746 T20743 arg2Of action,regulating
R10291 T20746 T20744 arg1Of action,the
R10292 T20746 T20745 arg1Of action,divergent
R10293 T20746 T20747 arg1Of action,of
R10294 T20748 T20749 arg1Of IL-6,and
R10295 T20749 T20747 arg2Of and,of
R10296 T20749 T20751 arg1Of and,[
R10297 T20750 T20749 arg2Of IL-10,and
R10298 T20752 T20751 arg2Of "8,9",[
R10299 T20753 T20751 arg3Of ],[
R10300 T20756 T20754 arg2Of contrary,On
R10301 T20756 T20755 arg1Of contrary,the
R10302 T20758 T20759 arg1Of SOCS1,is
R10303 T20758 T20760 arg1Of SOCS1,able
R10304 T20758 T20763 arg1Of SOCS1,inhibit
R10305 T20759 T20754 arg1Of is,On
R10306 T20759 T20757 arg1Of is,","
R10307 T20760 T20759 arg2Of able,is
R10308 T20763 T20760 arg2Of inhibit,able
R10309 T20763 T20761 arg1Of inhibit,to
R10310 T20763 T20762 arg1Of inhibit,partially
R10311 T20763 T20777 arg1Of inhibit,[
R10312 T20766 T20765 arg1Of activation,STAT3
R10313 T20766 T20767 arg1Of activation,and
R10314 T20767 T20764 arg1Of and,IL-10-mediated
R10315 T20767 T20773 arg1Of and,as
R10316 T20769 T20767 arg2Of responses,and
R10317 T20769 T20768 arg1Of responses,cellular
R10318 T20773 T20763 arg2Of as,inhibit
R10319 T20773 T20770 arg1Of as,","
R10320 T20773 T20771 arg1Of as,as
R10321 T20773 T20772 arg1Of as,well
R10322 T20776 T20773 arg2Of activation,as
R10323 T20776 T20774 arg1Of activation,IFN-γ-mediated
R10324 T20776 T20775 arg1Of activation,STAT1
R10325 T20778 T20777 arg2Of 32,[
R10326 T20779 T20777 arg3Of ],[
R10327 T20781 T20780 arg1Of determine,To
R10328 T20783 T20784 arg1Of SOCSs,were
R10329 T20783 T20785 arg2Of SOCSs,involved
R10330 T20785 T20781 arg2Of involved,determine
R10331 T20785 T20782 arg1Of involved,whether
R10332 T20785 T20784 arg2Of involved,were
R10333 T20785 T20786 arg1Of involved,in
R10334 T20791 T20786 arg2Of activation,in
R10335 T20791 T20787 arg1Of activation,the
R10336 T20791 T20788 arg1Of activation,defective
R10337 T20791 T20789 arg1Of activation,IL-10-induced
R10338 T20791 T20790 arg1Of activation,STAT3
R10339 T20791 T20792 arg1Of activation,of
R10340 T20796 T20792 arg2Of cells,of
R10341 T20796 T20793 arg1Of cells,RA
R10342 T20796 T20794 arg1Of cells,CD4+
R10343 T20796 T20795 arg1Of cells,T
R10344 T20799 T20798 arg1Of levels,the
R10345 T20799 T20800 arg1Of levels,of
R10346 T20799 T20806 arg1Of levels,in
R10347 T20799 T20816 arg1Of levels,from
R10348 T20799 T20819 arg1Of levels,were
R10349 T20799 T20820 arg2Of levels,compared
R10350 T20801 T20802 arg1Of SOCS1,and
R10351 T20803 T20802 arg2Of SOCS3,and
R10352 T20805 T20800 arg2Of expression,of
R10353 T20805 T20801 arg1Of expression,SOCS1
R10354 T20805 T20803 arg1Of expression,SOCS3
R10355 T20805 T20804 arg1Of expression,mRNA
R10356 T20806 T20815 arg1Of in,and
R10357 T20810 T20806 arg2Of cells,in
R10358 T20810 T20807 arg1Of cells,PB
R10359 T20810 T20808 arg1Of cells,CD4+
R10360 T20810 T20809 arg1Of cells,T
R10361 T20810 T20811 arg1Of cells,from
R10362 T20814 T20811 arg2Of patients,from
R10363 T20814 T20812 arg1Of patients,active
R10364 T20814 T20813 arg1Of patients,RA
R10365 T20816 T20815 arg2Of from,and
R10366 T20818 T20816 arg2Of controls,from
R10367 T20818 T20817 arg1Of controls,healthy
R10368 T20820 T20780 modOf compared,To
R10369 T20820 T20797 arg1Of compared,","
R10370 T20820 T20819 arg2Of compared,were
R10371 T20824 T20820 arg1Of PCR,compared
R10372 T20824 T20821 arg2Of PCR,by
R10373 T20824 T20822 arg1Of PCR,semiquantitative
R10374 T20824 T20823 arg1Of PCR,real-time
R10375 T20829 T20825 arg1Of cells,The
R10376 T20829 T20826 arg1Of cells,RA
R10377 T20829 T20827 arg1Of cells,CD4+
R10378 T20829 T20828 arg1Of cells,T
R10379 T20829 T20830 arg1Of cells,contained
R10380 T20832 T20831 arg1Of levels,higher
R10381 T20832 T20833 arg1Of levels,of
R10382 T20832 T20835 arg1Of levels,but
R10383 T20834 T20833 arg2Of SOCS1,of
R10384 T20835 T20830 arg2Of but,contained
R10385 T20835 T20841 arg1Of but,than
R10386 T20835 T20847 arg1Of but,(
R10387 T20837 T20835 arg2Of levels,but
R10388 T20837 T20836 arg1Of levels,lower
R10389 T20837 T20838 arg1Of levels,of
R10390 T20840 T20838 arg2Of transcripts,of
R10391 T20840 T20839 arg1Of transcripts,SOCS3
R10392 T20842 T20841 arg2Of did,than
R10393 T20846 T20842 arg1Of cells,did
R10394 T20846 T20843 arg1Of cells,control
R10395 T20846 T20844 arg1Of cells,CD4+
R10396 T20846 T20845 arg1Of cells,T
R10397 T20849 T20847 arg2Of 6a,(
R10398 T20849 T20848 arg1Of 6a,Fig.
R10399 T20850 T20847 arg3Of ),(
R10400 T20852 T20851 arg1Of expression,Constitutive
R10401 T20852 T20853 arg1Of expression,of
R10402 T20852 T20856 arg1Of expression,in
R10403 T20852 T20861 arg1Of expression,was
R10404 T20852 T20862 arg1Of expression,comparable
R10405 T20855 T20853 arg2Of mRNA,of
R10406 T20855 T20854 arg1Of mRNA,SOCS1
R10407 T20860 T20856 arg2Of cells,in
R10408 T20860 T20857 arg1Of cells,RA
R10409 T20860 T20858 arg1Of cells,CD4+
R10410 T20860 T20859 arg1Of cells,T
R10411 T20862 T20861 arg2Of comparable,was
R10412 T20862 T20863 arg1Of comparable,with
R10413 T20865 T20863 arg2Of expression,with
R10414 T20865 T20864 arg1Of expression,the
R10415 T20865 T20866 arg1Of expression,in
R10416 T20870 T20866 arg2Of cells,in
R10417 T20870 T20867 arg1Of cells,normal
R10418 T20870 T20868 arg1Of cells,CD4+
R10419 T20870 T20869 arg1Of cells,T
R10420 T20870 T20871 arg2Of cells,stimulated
R10421 T20871 T20880 arg1Of stimulated,","
R10422 T20871 T20881 modOf stimulated,supporting
R10423 T20873 T20874 arg1Of 10,ng/ml
R10424 T20875 T20871 arg1Of IL-6,stimulated
R10425 T20875 T20872 arg2Of IL-6,by
R10426 T20875 T20873 arg1Of IL-6,10
R10427 T20875 T20876 arg1Of IL-6,(
R10428 T20878 T20876 arg2Of 6b,(
R10429 T20878 T20877 arg1Of 6b,Fig.
R10430 T20879 T20876 arg3Of ),(
R10431 T20884 T20881 arg2Of significance,supporting
R10432 T20884 T20882 arg1Of significance,its
R10433 T20884 T20883 arg1Of significance,functional
R10434 T20888 T20885 arg1Of activation,Defective
R10435 T20888 T20886 arg1Of activation,IL-10-induced
R10436 T20888 T20887 arg1Of activation,STAT3
R10437 T20888 T20890 arg1Of activation,appears
R10438 T20888 T20892 arg1Of activation,be
R10439 T20888 T20893 arg1Of activation,due
R10440 T20890 T20889 arg1Of appears,therefore
R10441 T20892 T20890 arg2Of be,appears
R10442 T20892 T20891 arg1Of be,to
R10443 T20893 T20892 arg2Of due,be
R10444 T20893 T20898 arg1Of due,to
R10445 T20895 T20894 arg1Of least,at
R10446 T20896 T20895 arg1Of in,least
R10447 T20897 T20896 arg2Of part,in
R10448 T20898 T20896 arg1Of to,in
R10449 T20900 T20898 arg2Of abundance,to
R10450 T20900 T20899 arg1Of abundance,an
R10451 T20900 T20901 arg1Of abundance,of
R10452 T20900 T20903 arg1Of abundance,in
R10453 T20902 T20901 arg2Of SOCS1,of
R10454 T20907 T20903 arg2Of cells,in
R10455 T20907 T20904 arg1Of cells,RA
R10456 T20907 T20905 arg1Of cells,CD4+
R10457 T20907 T20906 arg1Of cells,T

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T18143 5019-5023 Antecedent denotes IL-6
T18142 5027-5043 Anaphor denotes the major factor
T18141 4873-4885 Antecedent denotes oncostatin M
T18140 4841-4867 Antecedent denotes leukemia inhibitory factor
T18139 4834-4839 Antecedent denotes IL-11
T18138 4828-4832 Antecedent denotes IL-6
T18137 4802-4826 Anaphor denotes IL-6 family of cytokines
T18136 4924-4947 Antecedent denotes epidermal growth factor
T18135 4888-4918 Antecedent denotes platelet-derived growth factor
T18134 4756-4789 Anaphor denotes many cytokines and growth factors
T14767 2544-2557 Antecedent denotes type 2 IL-10R
T14766 2508-2515 Antecedent denotes IL-10R1
T14765 2457-2469 Anaphor denotes two subunits
T15953 4466-4471 Antecedent denotes STAT3
T15952 4501-4505 Anaphor denotes STAT
T18147 6030-6034 Antecedent denotes IL-6
T18146 6068-6074 Anaphor denotes factor
T18145 5027-5043 Antecedent denotes the major factor
T18144 5065-5069 Anaphor denotes that
R7942 T15952 T15953 boundBy STAT,STAT3
R7449 T14765 T14766 boundBy two subunits,IL-10R1
R7450 T14765 T14767 boundBy two subunits,type 2 IL-10R
R8893 T18134 T18135 boundBy many cytokines and growth factors,platelet-derived growth factor
R8894 T18134 T18136 boundBy many cytokines and growth factors,epidermal growth factor
R8895 T18137 T18138 boundBy IL-6 family of cytokines,IL-6
R8896 T18137 T18139 boundBy IL-6 family of cytokines,IL-11
R8897 T18137 T18140 boundBy IL-6 family of cytokines,leukemia inhibitory factor
R8898 T18137 T18141 boundBy IL-6 family of cytokines,oncostatin M
R8899 T18142 T18143 boundBy the major factor,IL-6
R8900 T18144 T18142 boundBy that,the major factor
R8901 T18146 T18147 boundBy factor,IL-6

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T20502 8418-8421 Protein denotes CD4
T20501 8406-8411 Protein denotes SOCS1
T20500 8325-8330 Protein denotes STAT3
T20499 8311-8316 Protein denotes IL-10
T20498 8245-8249 Protein denotes IL-6
T20497 8209-8212 Protein denotes CD4
T20496 8151-8154 Protein denotes CD4
T20495 8134-8139 Protein denotes SOCS1
T20494 8083-8086 Protein denotes CD4
T20493 8048-8053 Protein denotes SOCS3
T20492 8022-8027 Protein denotes SOCS1
T20491 7982-7985 Protein denotes CD4
T20490 7863-7866 Protein denotes CD4
T20489 7835-7840 Protein denotes SOCS3
T20488 7825-7830 Protein denotes SOCS1
T20487 7797-7800 Protein denotes CD4
T20486 7774-7779 Protein denotes STAT3
T20485 7760-7765 Protein denotes IL-10
T20484 7679-7684 Protein denotes STAT1
T20483 7664-7669 Protein denotes IFN-γ
T20482 7612-7617 Protein denotes STAT3
T20481 7597-7602 Protein denotes IL-10
T20480 7562-7567 Protein denotes SOCS1
T20475 7429-7434 Protein denotes STAT3
T20474 7375-7380 Protein denotes SOCS3
T18162 5144-5148 Protein denotes IL-6
T18161 5105-5110 Protein denotes STAT3
T18160 5019-5023 Protein denotes IL-6
T18159 4964-4969 Protein denotes IL-10
T18158 4924-4947 Protein denotes epidermal growth factor
T18157 4888-4918 Protein denotes platelet-derived growth factor
T18156 4873-4885 Protein denotes oncostatin M
T18155 4841-4867 Protein denotes leukemia inhibitory factor
T18154 4834-4839 Protein denotes IL-11
T18153 4828-4832 Protein denotes IL-6
T18152 4734-4739 Protein denotes STAT3
T18151 4721-4724 Protein denotes CD4
T18150 4698-4703 Protein denotes IL-10
T18149 4658-4663 Protein denotes STAT3
T18148 4644-4648 Protein denotes IL-6
T18201 7075-7078 Protein denotes CD4
T18200 7063-7068 Protein denotes IL-10
T18199 6999-7004 Protein denotes STAT3
T18198 6953-6957 Protein denotes IL-6
T18197 6873-6878 Protein denotes IL-10
T18196 6828-6832 Protein denotes IL-6
T18195 6761-6766 Protein denotes IFN-γ
T18194 6732-6737 Protein denotes IL-10
T18193 6690-6694 Protein denotes IL-6
T18192 6650-6655 Protein denotes IFN-γ
T18191 6622-6627 Protein denotes IL-10
T18190 6565-6569 Protein denotes CD28
T18189 6525-6528 Protein denotes CD4
T18188 6499-6503 Protein denotes IL-6
T18187 6440-6443 Protein denotes CD4
T18186 6420-6425 Protein denotes IFN-γ
T18185 6403-6408 Protein denotes IL-10
T18184 6369-6373 Protein denotes IL-6
T18183 6300-6305 Protein denotes STAT1
T18182 6260-6265 Protein denotes STAT3
T18181 6226-6231 Protein denotes STAT1
T18180 6201-6205 Protein denotes IL-6
T18179 6128-6133 Protein denotes STAT1
T18178 6051-6056 Protein denotes STAT3
T18177 6030-6034 Protein denotes IL-6
T18176 5977-5981 Protein denotes IL-6
T18175 5918-5923 Protein denotes STAT3
T18174 5902-5907 Protein denotes STAT1
T18173 5888-5893 Protein denotes STAT3
T18172 5733-5737 Protein denotes IL-6
T18171 5602-5605 Protein denotes CD4
T18170 5519-5522 Protein denotes CD4
T18169 5504-5508 Protein denotes IL-6
T18168 5465-5470 Protein denotes STAT3
T18167 5455-5460 Protein denotes STAT1
T18166 5419-5424 Protein denotes IL-10
T18165 5384-5389 Protein denotes STAT3
T18164 5318-5322 Protein denotes IL-6
T18163 5279-5282 Protein denotes CD4
T15990 4620-4625 Protein denotes STAT3
T15989 4541-4546 Protein denotes STAT3
T15988 4527-4532 Protein denotes IL-10
T15987 4509-4512 Protein denotes CD4
T15986 4485-4490 Protein denotes IL-10
T15985 4466-4471 Protein denotes STAT3
T15984 4414-4417 Protein denotes CD4
T15983 4391-4394 Protein denotes CD4
T15982 4339-4344 Protein denotes STAT1
T15981 4325-4330 Protein denotes IL-10
T15980 4282-4285 Protein denotes CD4
T15979 4240-4245 Protein denotes STAT3
T15978 4226-4231 Protein denotes IL-10
T15977 4190-4195 Protein denotes STAT3
T15976 4168-4173 Protein denotes IL-10
T15975 4089-4094 Protein denotes STAT3
T15974 4033-4038 Protein denotes STAT3
T15973 3996-3999 Protein denotes CD4
T15972 3948-3953 Protein denotes STAT3
T15971 3908-3911 Protein denotes CD4
T15970 3870-3875 Protein denotes IL-10
T15969 3813-3818 Protein denotes STAT3
T15968 3713-3716 Protein denotes CD4
T15967 3701-3706 Protein denotes IL-10
T15966 3676-3681 Protein denotes STAT3
T15965 3666-3671 Protein denotes STAT1
T15964 3622-3627 Protein denotes STAT3
T15963 3487-3492 Protein denotes IL-10
T15962 3456-3461 Protein denotes STAT3
T15961 3417-3422 Protein denotes STAT3
T15960 3386-3391 Protein denotes STAT3
T15959 3376-3381 Protein denotes STAT1
T15958 3286-3291 Protein denotes IL-10
T15957 3274-3280 Protein denotes IL-10R
T15956 3242-3245 Protein denotes CD4
T15955 3214-3219 Protein denotes STAT3
T15954 3199-3204 Protein denotes IL-10
T14768 2377-2384 Protein denotes IL-10R1
T14782 3161-3164 Protein denotes CD4
T14781 3136-3141 Protein denotes IL-10
T14780 2969-2972 Protein denotes CD4
T14779 2947-2954 Protein denotes IL-10R1
T14778 2799-2802 Protein denotes CD4
T14777 2785-2792 Protein denotes IL-10R1
T14776 2701-2704 Protein denotes CD4
T14775 2678-2683 Protein denotes IL-10
T14774 2629-2634 Protein denotes IL-10
T14773 2563-2570 Protein denotes IL-10R1
T14772 2544-2557 Protein denotes type 2 IL-10R
T14771 2508-2515 Protein denotes IL-10R1
T14770 2439-2444 Protein denotes IL-10
T14769 2391-2394 Protein denotes CD4
T12929 2308-2313 Protein denotes IL-10
T12913 1101-1106 Protein denotes IL-10
T12912 1055-1059 Protein denotes CD28
T12911 1047-1050 Protein denotes CD3
T12910 1028-1031 Protein denotes CD4
T12909 1008-1013 Protein denotes IFN-γ
T12908 941-946 Protein denotes IL-10
T12907 887-892 Protein denotes IL-10
T12906 854-859 Protein denotes IFN-γ
T12905 797-800 Protein denotes CD4
T12904 778-783 Protein denotes IL-10
T12903 708-711 Protein denotes CD4
T12902 671-676 Protein denotes IFN-γ
T12901 611-616 Protein denotes IFN-γ
T12900 587-592 Protein denotes IL-10
T12899 531-535 Protein denotes CD28
T12898 509-512 Protein denotes CD3
T12897 393-396 Protein denotes CD4
T12896 374-379 Protein denotes IL-10
T12895 358-361 Protein denotes CD4
T12894 240-244 Protein denotes CD28
T20473 7193-7198 Protein denotes SOCS3
T20472 7183-7188 Protein denotes SOCS1
T20471 7139-7143 Protein denotes IL-6
T20470 7126-7129 Protein denotes CD4
T20469 7109-7114 Protein denotes SOCS1
T20479 7532-7537 Protein denotes IL-10
T20478 7523-7527 Protein denotes IL-6
T20477 7473-7478 Protein denotes IL-10
T20476 7457-7461 Protein denotes IL-6
T12893 184-189 Protein denotes IL-10
T12892 83-87 Protein denotes CD28
T12891 66-69 Protein denotes CD4
T12890 43-48 Protein denotes IFN-γ
T12889 23-28 Protein denotes IL-10
T12928 2237-2240 Protein denotes CD4
T12927 2051-2056 Protein denotes IL-10
T12926 2007-2011 Protein denotes IL-2
T12925 1943-1948 Protein denotes IL-10
T12924 1905-1909 Protein denotes CD28
T12923 1878-1881 Protein denotes CD4
T12922 1859-1863 Protein denotes IL-2
T12921 1810-1813 Protein denotes CD4
T12920 1788-1793 Protein denotes IL-10
T12919 1755-1760 Protein denotes IFN-γ
T12918 1692-1695 Protein denotes CD4
T12917 1441-1446 Protein denotes IFN-γ
T12916 1432-1437 Protein denotes IL-10
T12915 1361-1366 Protein denotes IL-10
T12914 1336-1341 Protein denotes IFN-γ

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T20638 7664-7669 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T20637 8311-8316 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T20636 7760-7765 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T20635 7597-7602 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T20634 7532-7537 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T20633 7473-7478 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T20632 8325-8330 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T20631 7774-7779 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T20630 7612-7617 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T20629 7429-7434 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T20628 8245-8249 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T20627 7523-7527 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T20626 7457-7461 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T20625 7139-7143 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T20624 8418-8421 http://www.uniprot.org/uniprot/P01730 denotes CD4
T20623 8209-8212 http://www.uniprot.org/uniprot/P01730 denotes CD4
T20622 8151-8154 http://www.uniprot.org/uniprot/P01730 denotes CD4
T20621 8083-8086 http://www.uniprot.org/uniprot/P01730 denotes CD4
T20620 7982-7985 http://www.uniprot.org/uniprot/P01730 denotes CD4
T20619 7863-7866 http://www.uniprot.org/uniprot/P01730 denotes CD4
T20618 7797-7800 http://www.uniprot.org/uniprot/P01730 denotes CD4
T20617 7126-7129 http://www.uniprot.org/uniprot/P01730 denotes CD4
T20616 8406-8411 http://www.uniprot.org/uniprot/O15524 denotes SOCS1
T20615 8134-8139 http://www.uniprot.org/uniprot/O15524 denotes SOCS1
T20614 8022-8027 http://www.uniprot.org/uniprot/O15524 denotes SOCS1
T20613 7825-7830 http://www.uniprot.org/uniprot/O15524 denotes SOCS1
T20612 7562-7567 http://www.uniprot.org/uniprot/O15524 denotes SOCS1
T20611 7183-7188 http://www.uniprot.org/uniprot/O15524 denotes SOCS1
T20610 7109-7114 http://www.uniprot.org/uniprot/O15524 denotes SOCS1
T18440 6565-6569 http://www.uniprot.org/uniprot/P10747 denotes CD28
T18439 6557-6560 http://www.uniprot.org/uniprot/P09693 denotes CD3
T18438 6557-6560 http://www.uniprot.org/uniprot/P07766 denotes CD3
T18437 6557-6560 http://www.uniprot.org/uniprot/P04234 denotes CD3
T18436 6557-6560 http://www.uniprot.org/uniprot/P20963 denotes CD3
T18435 6761-6766 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T18434 6650-6655 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T18433 6420-6425 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T18432 7075-7078 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18431 6525-6528 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18430 6440-6443 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18429 5602-5605 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18428 5519-5522 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18427 5279-5282 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18426 4721-4724 http://www.uniprot.org/uniprot/P01730 denotes CD4
T18425 7063-7068 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18424 6873-6878 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18423 6732-6737 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18422 6622-6627 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18421 6403-6408 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18420 5419-5424 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18419 4964-4969 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18418 4698-4703 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T18417 6999-7004 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18416 6260-6265 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18415 6051-6056 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18414 5918-5923 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18413 5888-5893 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18412 5465-5470 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18411 5384-5389 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18410 5105-5110 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18409 4734-4739 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18408 4658-4663 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T18407 6953-6957 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18406 6828-6832 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18405 6690-6694 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18404 6499-6503 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18403 6369-6373 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18402 6201-6205 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18401 6030-6034 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18400 5977-5981 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18399 5733-5737 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18398 5504-5508 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18397 5318-5322 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18396 5144-5148 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18395 5019-5023 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18394 4828-4832 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18393 4802-4806 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T18392 4644-4648 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T16156 4509-4512 http://www.uniprot.org/uniprot/P01730 denotes CD4
T16155 4414-4417 http://www.uniprot.org/uniprot/P01730 denotes CD4
T16154 4391-4394 http://www.uniprot.org/uniprot/P01730 denotes CD4
T16153 4282-4285 http://www.uniprot.org/uniprot/P01730 denotes CD4
T16152 3996-3999 http://www.uniprot.org/uniprot/P01730 denotes CD4
T16151 3908-3911 http://www.uniprot.org/uniprot/P01730 denotes CD4
T16150 3713-3716 http://www.uniprot.org/uniprot/P01730 denotes CD4
T16149 3242-3245 http://www.uniprot.org/uniprot/P01730 denotes CD4
T16148 4620-4625 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16147 4541-4546 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16146 4466-4471 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16145 4240-4245 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16144 4190-4195 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16143 4089-4094 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16142 4033-4038 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16141 3948-3953 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16140 3813-3818 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16139 3676-3681 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16138 3622-3627 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16137 3456-3461 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16136 3417-3422 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16135 3386-3391 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16134 3214-3219 http://www.uniprot.org/uniprot/P40763 denotes STAT3
T16133 4527-4532 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T16132 4485-4490 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T16131 4325-4330 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T16130 4226-4231 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T16129 4168-4173 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T16128 3870-3875 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T16127 3701-3706 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T16126 3487-3492 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T16125 3286-3291 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T16124 3199-3204 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T14820 2549-2553 http://www.uniprot.org/uniprot/P60568 denotes 2 IL
T14819 3136-3141 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T14818 2678-2683 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T14817 2629-2634 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T14816 2439-2444 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T14815 3161-3164 http://www.uniprot.org/uniprot/P01730 denotes CD4
T14814 2969-2972 http://www.uniprot.org/uniprot/P01730 denotes CD4
T14813 2799-2802 http://www.uniprot.org/uniprot/P01730 denotes CD4
T14812 2701-2704 http://www.uniprot.org/uniprot/P01730 denotes CD4
T14811 2391-2394 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13115 2007-2011 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T13114 1859-1863 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T13113 1897-1900 http://www.uniprot.org/uniprot/P09693 denotes CD3
T13112 1047-1050 http://www.uniprot.org/uniprot/P09693 denotes CD3
T13111 509-512 http://www.uniprot.org/uniprot/P09693 denotes CD3
T13110 1897-1900 http://www.uniprot.org/uniprot/P07766 denotes CD3
T13109 1047-1050 http://www.uniprot.org/uniprot/P07766 denotes CD3
T13108 509-512 http://www.uniprot.org/uniprot/P07766 denotes CD3
T13107 1897-1900 http://www.uniprot.org/uniprot/P04234 denotes CD3
T13106 1047-1050 http://www.uniprot.org/uniprot/P04234 denotes CD3
T13105 509-512 http://www.uniprot.org/uniprot/P04234 denotes CD3
T13104 1897-1900 http://www.uniprot.org/uniprot/P20963 denotes CD3
T13103 1047-1050 http://www.uniprot.org/uniprot/P20963 denotes CD3
T13102 509-512 http://www.uniprot.org/uniprot/P20963 denotes CD3
T13101 1905-1909 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13100 1055-1059 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13099 531-535 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13098 240-244 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13097 83-87 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13096 2237-2240 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13095 1878-1881 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13094 1810-1813 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13093 1692-1695 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13092 1028-1031 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13091 797-800 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13090 708-711 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13089 393-396 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13088 358-361 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13087 66-69 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13086 1755-1760 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13085 1441-1446 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13073 1361-1366 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13072 1101-1106 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13071 941-946 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13070 887-892 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13069 778-783 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13068 587-592 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13067 374-379 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13066 184-189 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13065 23-28 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13084 1336-1341 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13083 1008-1013 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13082 854-859 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13081 671-676 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13080 611-616 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13079 43-48 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13078 2308-2313 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13077 2051-2056 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13076 1943-1948 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13075 1788-1793 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13074 1432-1437 http://www.uniprot.org/uniprot/P22301 denotes IL-10

UBERON-AE

Id Subject Object Predicate Lexical cue
T17463 6947-6952 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17462 6337-6342 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17461 6151-6156 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17460 5835-5840 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17459 5681-5686 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T17458 5330-5335 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T17457 5050-5064 http://purl.obolibrary.org/obo/UBERON_0001090 denotes synovial fluid

GO-BP

Id Subject Object Predicate Lexical cue
T20406 7633-7641 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T20405 7618-7651 http://purl.obolibrary.org/obo/GO_1900039 denotes activation and cellular responses
T20404 7618-7651 http://purl.obolibrary.org/obo/GO_1900036 denotes activation and cellular responses
T20403 7618-7651 http://purl.obolibrary.org/obo/GO_0010186 denotes activation and cellular responses
T20402 7351-7369 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T20401 7351-7360 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T20400 7342-7369 http://purl.obolibrary.org/obo/GO_0019221 denotes cytokine-signaling pathways
T18034 6747-6766 http://purl.obolibrary.org/obo/GO_1902714 denotes inhibition of IFN-γ
T18033 6306-6315 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T18032 5977-5990 http://purl.obolibrary.org/obo/GO_0004915 denotes IL-6 activity
T18031 5471-5500 http://purl.obolibrary.org/obo/GO_0042327 denotes phosphorylation was activated
T18030 5330-5347 http://purl.obolibrary.org/obo/GO_0008015 denotes blood circulation
T18029 4905-4933 http://purl.obolibrary.org/obo/GO_0070849 denotes growth factor, and epidermal
T18028 4905-4933 http://purl.obolibrary.org/obo/GO_0007174 denotes growth factor, and epidermal
T18027 4934-4940 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T18026 4905-4911 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T18025 4775-4781 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T18024 4664-4694 http://purl.obolibrary.org/obo/GO_0042326 denotes phosphorylation and inhibition
T18023 5869-5884 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18022 5777-5792 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18021 5471-5486 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T18020 4664-4679 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T15877 3507-3529 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T15876 3502-3529 http://purl.obolibrary.org/obo/GO_0050728 denotes anti-inflammatory responses
T15875 3354-3367 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T15874 3309-3339 http://purl.obolibrary.org/obo/GO_0042327 denotes phosphorylation and activation
T15873 3300-3339 http://purl.obolibrary.org/obo/GO_0050731 denotes tyrosine phosphorylation and activation
T15872 3274-3280 http://purl.obolibrary.org/obo/GO_0004920 denotes IL-10R
T15871 4626-4641 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T14740 3112-3124 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T14739 3105-3132 http://purl.obolibrary.org/obo/GO_0036499 denotes signal transduction pathway
T14738 3105-3132 http://purl.obolibrary.org/obo/GO_0036500 denotes signal transduction pathway
T14737 3105-3132 http://purl.obolibrary.org/obo/GO_0036498 denotes signal transduction pathway
T14736 3105-3124 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T14735 3105-3111 http://purl.obolibrary.org/obo/GO_0023052 denotes signal
T14734 3091-3132 http://purl.obolibrary.org/obo/GO_1902531 denotes intracellular signal transduction pathway
T14733 3091-3132 http://purl.obolibrary.org/obo/GO_1902532 denotes intracellular signal transduction pathway
T14732 3091-3132 http://purl.obolibrary.org/obo/GO_0035556 denotes intracellular signal transduction pathway
T14731 3091-3132 http://purl.obolibrary.org/obo/GO_1902533 denotes intracellular signal transduction pathway
T14730 2607-2631 http://purl.obolibrary.org/obo/GO_0071353 denotes cellular responses to IL
T14729 2607-2631 http://purl.obolibrary.org/obo/GO_0071352 denotes cellular responses to IL
T14728 2607-2631 http://purl.obolibrary.org/obo/GO_0071351 denotes cellular responses to IL
T14727 2607-2631 http://purl.obolibrary.org/obo/GO_0071349 denotes cellular responses to IL
T14726 2607-2631 http://purl.obolibrary.org/obo/GO_0097398 denotes cellular responses to IL
T14725 2607-2631 http://purl.obolibrary.org/obo/GO_0097397 denotes cellular responses to IL
T14724 2607-2631 http://purl.obolibrary.org/obo/GO_0071348 denotes cellular responses to IL
T14723 2607-2631 http://purl.obolibrary.org/obo/GO_0036016 denotes cellular responses to IL
T14722 2607-2631 http://purl.obolibrary.org/obo/GO_0035963 denotes cellular responses to IL
T14721 2607-2631 http://purl.obolibrary.org/obo/GO_0071350 denotes cellular responses to IL
T14720 2607-2615 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T14719 2551-2557 http://purl.obolibrary.org/obo/GO_0004920 denotes IL-10R
T12824 2007-2022 http://purl.obolibrary.org/obo/GO_0032663 denotes IL-2 production
T12823 1859-1874 http://purl.obolibrary.org/obo/GO_0032663 denotes IL-2 production
T12822 2007-2022 http://purl.obolibrary.org/obo/GO_0032623 denotes IL-2 production
T12821 1859-1874 http://purl.obolibrary.org/obo/GO_0032623 denotes IL-2 production
T12820 675-700 http://purl.obolibrary.org/obo/GO_0032729 denotes γ production by activated
T12819 254-269 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T12818 168-189 http://purl.obolibrary.org/obo/GO_0032613 denotes production, and IL-10
T12817 168-189 http://purl.obolibrary.org/obo/GO_0032653 denotes production, and IL-10
T12816 159-178 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T12815 154-178 http://purl.obolibrary.org/obo/GO_0035745 denotes cell cytokine production
T12814 154-178 http://purl.obolibrary.org/obo/GO_0035744 denotes cell cytokine production
T12813 154-178 http://purl.obolibrary.org/obo/GO_0002368 denotes cell cytokine production
T12812 154-178 http://purl.obolibrary.org/obo/GO_0032762 denotes cell cytokine production
T12811 154-178 http://purl.obolibrary.org/obo/GO_0002371 denotes cell cytokine production
T12810 154-178 http://purl.obolibrary.org/obo/GO_0002370 denotes cell cytokine production
T12809 152-178 http://purl.obolibrary.org/obo/GO_0002724 denotes T-cell cytokine production
T12808 152-178 http://purl.obolibrary.org/obo/GO_0002369 denotes T-cell cytokine production
T12807 29-48 http://purl.obolibrary.org/obo/GO_1902714 denotes inhibition of IFN-γ
T15870 4345-4360 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T15869 4246-4261 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T15868 4196-4211 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T15867 4095-4110 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T15866 4039-4054 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T15865 3819-3834 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T15864 3682-3697 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T15863 3309-3324 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T15862 3220-3235 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation

GO-CC

Id Subject Object Predicate Lexical cue
T20519 8425-8430 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T20518 8216-8221 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T20517 8158-8163 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T20516 8090-8095 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T20515 7989-7994 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T20514 7870-7875 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T20513 7804-7809 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T20512 7133-7138 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18245 5758-5766 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T18244 5738-5746 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T18243 5758-5766 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T18242 5738-5746 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T18241 7082-7087 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18240 6718-6723 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18239 6532-6537 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18238 6447-6452 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18237 5609-5614 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18236 5526-5531 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18235 5286-5291 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18234 5126-5131 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18233 4728-4733 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16009 4516-4521 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16008 4421-4426 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16007 4398-4403 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16006 4289-4294 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16005 4001-4006 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16004 3915-3920 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T14810 3091-3104 http://purl.obolibrary.org/obo/GO_0005622 denotes intracellular
T14809 2419-2441 http://purl.obolibrary.org/obo/GO_0045323 denotes receptor complex of IL
T14808 2419-2441 http://purl.obolibrary.org/obo/GO_0072536 denotes receptor complex of IL
T14807 2419-2441 http://purl.obolibrary.org/obo/GO_0005893 denotes receptor complex of IL
T14806 2419-2441 http://purl.obolibrary.org/obo/GO_0042022 denotes receptor complex of IL
T14805 2419-2441 http://purl.obolibrary.org/obo/GO_0032002 denotes receptor complex of IL
T14804 2419-2441 http://purl.obolibrary.org/obo/GO_0045092 denotes receptor complex of IL
T14803 2419-2441 http://purl.obolibrary.org/obo/GO_0016516 denotes receptor complex of IL
T14802 2419-2441 http://purl.obolibrary.org/obo/GO_0030876 denotes receptor complex of IL
T14801 2419-2441 http://purl.obolibrary.org/obo/GO_0005897 denotes receptor complex of IL
T14800 2419-2441 http://purl.obolibrary.org/obo/GO_0005895 denotes receptor complex of IL
T14799 2419-2435 http://purl.obolibrary.org/obo/GO_0043235 denotes receptor complex
T14798 2758-2770 http://purl.obolibrary.org/obo/GO_0009986 denotes cell surface
T14797 2364-2376 http://purl.obolibrary.org/obo/GO_0009986 denotes cell surface
T14796 3168-3173 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T14795 2976-2981 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T14794 2806-2811 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T14793 2758-2762 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T14792 2364-2368 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T12964 536-544 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T12963 513-521 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T12962 536-544 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T12961 513-521 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T12960 2244-2249 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12959 1885-1890 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12958 1817-1822 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12957 1699-1704 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12956 1035-1040 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12955 804-809 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12954 715-720 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12953 400-405 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12952 365-370 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12951 73-78 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16003 3720-3725 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T16002 3249-3254 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

GO-MF

Id Subject Object Predicate Lexical cue
T20511 8311-8316 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T20510 7760-7765 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T20509 7597-7602 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T20508 7532-7537 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T20507 7473-7478 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T20506 8245-8249 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T20505 7523-7527 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T20504 7457-7461 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T20503 7139-7143 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18232 5977-5990 http://purl.obolibrary.org/obo/GO_0004915 denotes IL-6 activity
T18231 5758-5766 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T18230 5738-5746 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T18229 4905-4933 http://purl.obolibrary.org/obo/GO_0048408 denotes growth factor, and epidermal
T18228 4905-4933 http://purl.obolibrary.org/obo/GO_0005154 denotes growth factor, and epidermal
T18227 4873-4885 http://purl.obolibrary.org/obo/GO_0005147 denotes oncostatin M
T18226 4834-4839 http://purl.obolibrary.org/obo/GO_0005142 denotes IL-11
T18225 7063-7068 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18224 6873-6878 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18223 6732-6737 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18222 6622-6627 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18221 6403-6408 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18220 5419-5424 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18219 4964-4969 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18218 4698-4703 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T18217 6953-6957 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18216 6828-6832 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18215 6690-6694 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18214 6499-6503 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18213 6369-6373 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18212 6201-6205 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18211 6030-6034 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18210 5977-5981 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18209 5733-5737 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18208 5504-5508 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18207 5318-5322 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18206 5144-5148 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18205 5019-5023 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18204 4828-4832 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18203 4802-4806 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T18202 4644-4648 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T15993 3487-3492 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T15992 3286-3291 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T15991 3199-3204 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12950 2007-2011 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T12949 1859-1863 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T12948 536-544 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T12947 513-521 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T12946 274-314 http://purl.obolibrary.org/obo/GO_0043548 denotes binding of phosphatidylinositol 3-kinase
T12945 274-307 http://purl.obolibrary.org/obo/GO_0032266 denotes binding of phosphatidylinositol 3
T12944 274-281 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12943 2308-2313 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12942 2051-2056 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12941 1943-1948 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12940 1788-1793 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12939 1432-1437 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12938 1361-1366 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12937 1101-1106 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12936 941-946 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12935 887-892 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12934 778-783 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12933 587-592 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12932 374-379 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12931 184-189 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12930 23-28 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T14791 2559-2565 http://purl.obolibrary.org/obo/GO_0005149 denotes 1]. IL
T14790 2551-2557 http://purl.obolibrary.org/obo/GO_0004920 denotes IL-10R
T14789 2549-2553 http://purl.obolibrary.org/obo/GO_0005134 denotes 2 IL
T14788 2490-2497 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T14787 2483-2489 http://purl.obolibrary.org/obo/GO_0005488 denotes ligand
T14786 3136-3141 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T14785 2678-2683 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T14784 2629-2634 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T14783 2439-2444 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T16001 3274-3280 http://purl.obolibrary.org/obo/GO_0004920 denotes IL-10R
T16000 4527-4532 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T15999 4485-4490 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T15998 4325-4330 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T15997 4226-4231 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T15996 4168-4173 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T15995 3870-3875 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T15994 3701-3706 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10

sentences

Id Subject Object Predicate Lexical cue
T20399 8301-8431 Sentence denotes Defective IL-10-induced STAT3 activation therefore appears to be due at least in part to an abundance of SOCS1 in RA CD4+ T cells.
T20398 8107-8300 Sentence denotes Constitutive expression of SOCS1 mRNA in RA CD4+ T cells was comparable with the expression in normal CD4+ T cells stimulated by 10 ng/ml IL-6 (Fig. 6b), supporting its functional significance.
T20397 7975-8106 Sentence denotes The RA CD4+ T cells contained higher levels of SOCS1 but lower levels of SOCS3 transcripts than did control CD4+ T cells (Fig. 6a).
T20396 7702-7974 Sentence denotes To determine whether SOCSs were involved in the defective IL-10-induced STAT3 activation of RA CD4+ T cells, the levels of SOCS1 and SOCS3 mRNA expression in PB CD4+ T cells from active RA patients and from healthy controls were compared by semiquantitative real-time PCR.
T20395 7545-7701 Sentence denotes On the contrary, SOCS1 is able to partially inhibit IL-10-mediated STAT3 activation and cellular responses, as well as IFN-γ-mediated STAT1 activation [32].
T20394 7375-7544 Sentence denotes SOCS3 has recently been shown to specifically inhibit STAT3 activation induced by IL-6 but not by IL-10, thereby regulating the divergent action of IL-6 and IL-10 [8,9].
T20393 7139-7374 Sentence denotes IL-6 induces two potent inhibitors of JAKs (SOCS1 and SOCS3 proteins) that not only act as mediators of negative feedback inhibition, but also play a major role in crosstalk inhibition by opposing other cytokine-signaling pathways [7].
T20392 7090-7138 Sentence denotes High expression of SOCS1 mRNA in RA CD4+ T cells
T18019 6880-7088 Sentence denotes Taken together, these findings suggest that persistent exposure to serum IL-6 may have a role in both the induction of STAT3 activation and the resistance to the inhibitory effect of IL-10 in RA CD4+ T cells.
T18018 6690-6879 Sentence denotes IL-6 pretreatment of normal cells reduced IL-10-mediated inhibition of IFN-γ production (Fig. 5b), indicating that high concentrations of IL-6 could modulate T-cell responsiveness to IL-10.
T18017 6454-6689 Sentence denotes After preincubation with or without 10 ng/ml IL-6 for 36 hours, normal CD4+ T cells were stimulated by CD3 and CD28 costimulation in the presence or absence of 1 ng/ml IL-10 for 36 hours, and the IFN-γ production was measured by ELISA.
T18016 6344-6453 Sentence denotes We next examined whether IL-6 could suppress the effect of IL-10 to inhibit IFN-γ production by CD4+ T cells.
T18015 6116-6343 Sentence denotes The lack of STAT1 activation by RA serum suggests that much higher concentrations of IL-6 may be required for STAT1 activation as compared with STAT3 activation, or that inhibitors of STAT1 signaling may be present in RA serum.
T18014 6002-6115 Sentence denotes These results indicate that IL-6 is the dominant STAT3-activating factor contained in sera of active RA patients.
T18013 5832-6001 Sentence denotes RA serum was able to induce tyrosine phosphorylation of STAT3 but not STAT1, and this STAT3 activation was mostly abolished by neutralization of IL-6 activity (Fig. 5a).
T18012 5595-5831 Sentence denotes Normal CD4+ T cells were thus incubated for 20 min with culture medium containing 30% serum from active RA patients and neutralizing anti-IL-6 antibody or control antibody, and STAT phosphorylation was examined by western blot analysis.
T18011 5450-5594 Sentence denotes Both STAT1 and STAT3 phosphorylation was activated by IL-6 in normal CD4+ T cells (data not shown), in agreement with previous observations [4].
T18010 5138-5449 Sentence denotes Since IL-6 is also abundant in sera of active RA patients, frequently detected at > 1 ng/ml [27], we examined whether persistent exposure of CD4+ T cells to high concentrations of IL-6 in the blood circulation was responsible for their sustained STAT3 activation and resistance to IL-10 inhibition in active RA.
T18009 4734-5137 Sentence denotes STAT3 is activated by many cytokines and growth factors such as the IL-6 family of cytokines (IL-6, IL-11, leukemia inhibitory factor, and oncostatin M), platelet-derived growth factor, and epidermal growth factor, in addition to IL-10 [4], but previous studies have demonstrated that IL-6 is the major factor in RA synovial fluid that induces constitutive activation of STAT3 in mononuclear cells [31].
T18008 4644-4733 Sentence denotes IL-6-mediated STAT3 phosphorylation and inhibition of IL-10 effect in normal CD4+ T cells
T14718 3060-3187 Sentence denotes These results suggest that the intracellular signal transduction pathway of IL-10 may be impaired in CD4+ T cells of active RA.
T14717 2906-3059 Sentence denotes As shown in Fig. 3a,3b, the intensity of IL-10R1 expression on CD4+ T cells was significantly increased in RA patients compared with in healthy controls.
T14716 2641-2905 Sentence denotes To examine whether the resistance to IL-10 inhibition in RA CD4+ T cells was due to limited receptor expression, the cell surface expression of IL-10R1 on PB CD4+ T cells from active RA patients and from healthy controls was determined by flow cytometric analysis.
T14715 2563-2640 Sentence denotes IL-10R1 expression plays a critical role in cellular responses to IL-10 [29].
T14714 2404-2562 Sentence denotes The functional receptor complex of IL-10 consists of two subunits, the primary ligand-binding component IL-10R1 and the accessory component type 2 IL-10R [1].
T14713 2340-2403 Sentence denotes Increased expression of cell surface IL-10R1 on RA CD4+ T cells
T12806 2190-2338 Sentence denotes Taken together, these results indicate that RA CD4+ T cells become less susceptible to the immunoregulatory effect of IL-10 during the active phase.
T12805 1996-2189 Sentence denotes Similarly, IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease, -2.1 ± 13.8%), while it was significantly reduced in healthy controls (61.1 ± 13.7%; P < 0.05).
T12804 1834-1995 Sentence denotes In addition, we compared IL-2 production by CD4+ T cells after CD3 and CD28 costimulation in the presence of IL-10 in active RA patients and in healthy controls.
T12803 1674-1833 Sentence denotes As a consequence, CD4+ T cells from active RA patients produced higher levels of IFN-γ in the presence of 1 ng/ml IL-10 than did normal CD4+ T cells (Fig. 2a).
T12802 1281-1673 Sentence denotes There were no statistically significant differences in IFN-γ production without IL-10 among these three groups (Fig. 2a), but the inhibitory effect of IL-10 on IFN-γ production was significantly limited in the active RA group as compared with the inactive RA group and healthy controls (percentage decrease: active RA, 2.9 ± 14.4%; inactive RA, 45.6 ± 14.4%; controls, 65.8 ± 7.9%) (Fig. 2b).
T12801 977-1280 Sentence denotes We thus compared the levels of IFN-γ production by CD4+ T cells after CD3 and CD28 costimulation in the presence of 1 ng/ml IL-10 in RA patients with active disease (multiple inflammatory joints, CRP level ≥ 10 mg/l) and inactive disease (in remission, CRP level < 10 mg/l) [26] and in healthy controls.
T12800 785-976 Sentence denotes However, RA CD4+ T cells were able to produce significant amounts of IFN-γ in the presence of 1 ng/ml IL-10, and the maximal but not complete inhibition by IL-10 was obtained at 10–100 ng/ml.
T12799 651-784 Sentence denotes As shown in Fig. 1, IFN-γ production by activated normal CD4+ T cells was mostly inhibited at concentrations as low as 1 ng/ml IL-10.
T12798 321-650 Sentence denotes To evaluate the responsiveness of RA CD4+ T cells to IL-10, purified PB CD4+ T cells from three patients with active RA and from three healthy controls were stimulated by immobilized anti-CD3 antibody and anti-CD28 antibody with or without diluted concentrations of IL-10 for 36 hours, and IFN-γ production was measured by ELISA.
T12797 79-320 Sentence denotes The CD28 costimulatory pathway is crucial for effective antigen-specific T-cell cytokine production, and IL-10 can directly suppress this response by inhibiting CD28 tyrosine phosphorylation and binding of phosphatidylinositol 3-kinase [24].
T12796 9-78 Sentence denotes Resistance to IL-10 inhibition of IFN-γ production in RA CD4+ T cells
T15861 4438-4642 Sentence denotes These results indicate that STAT3 is the major IL-10-activated STAT in CD4+ T cells, and IL-10-induced STAT3 activation may be diminished in active RA, in association with sustained STAT3 phosphorylation.
T15860 4306-4437 Sentence denotes On the other hand, IL-10-induced STAT1 phosphorylation was not detected in either RA CD4+ T cells or normal CD4+ T cells (Fig. 4a).
T15859 4175-4305 Sentence denotes Both sustained STAT3 phosphorylation and defective IL-10-induced STAT3 phosphorylation were found in RA ST CD4+ T cells (Fig. 4c).
T15858 4089-4174 Sentence denotes STAT3 phosphorylation was augmented only when activated by as much as 10 ng/ml IL-10.
T15857 3935-4088 Sentence denotes In contrast, STAT3 was phosphorylated in freshly isolated PB CD4+ cells from RA patients and this STAT3 phosphorylation was detectable for up to 6 hours.
T15856 3813-3934 Sentence denotes STAT3 phosphorylation was dose-dependently induced after IL-10 activation for 20 min in normal CD4+ T cells (Fig. 4a,4b).
T15855 3649-3812 Sentence denotes The induction of STAT1 and STAT3 phosphorylation by IL-10 in PB CD4+ T cells from active RA patients and from healthy controls was examined using western blotting.
T15854 3397-3648 Sentence denotes Macrophage-specific STAT3-deficient mice demonstrated that STAT3 plays a dominant role in IL-10-mediated anti-inflammatory responses [5], which has recently been confirmed in human macrophages by studies of dominant-negative STAT3 overexpression [30].
T15853 3255-3396 Sentence denotes The interaction of IL-10R with IL-10 induces tyrosine phosphorylation and activation of the latent transcription factors STAT1 and STAT3 [3].
T15852 3189-3254 Sentence denotes Defective IL-10-mediated STAT3 phosphorylation in RA CD4+ T cells
T91 0-7 Sentence denotes Results
T92 9-78 Sentence denotes Resistance to IL-10 inhibition of IFN-γ production in RA CD4+ T cells
T93 79-320 Sentence denotes The CD28 costimulatory pathway is crucial for effective antigen-specific T-cell cytokine production, and IL-10 can directly suppress this response by inhibiting CD28 tyrosine phosphorylation and binding of phosphatidylinositol 3-kinase [24].
T94 321-650 Sentence denotes To evaluate the responsiveness of RA CD4+ T cells to IL-10, purified PB CD4+ T cells from three patients with active RA and from three healthy controls were stimulated by immobilized anti-CD3 antibody and anti-CD28 antibody with or without diluted concentrations of IL-10 for 36 hours, and IFN-γ production was measured by ELISA.
T95 651-784 Sentence denotes As shown in Fig. 1, IFN-γ production by activated normal CD4+ T cells was mostly inhibited at concentrations as low as 1 ng/ml IL-10.
T96 785-976 Sentence denotes However, RA CD4+ T cells were able to produce significant amounts of IFN-γ in the presence of 1 ng/ml IL-10, and the maximal but not complete inhibition by IL-10 was obtained at 10–100 ng/ml.
T97 977-1280 Sentence denotes We thus compared the levels of IFN-γ production by CD4+ T cells after CD3 and CD28 costimulation in the presence of 1 ng/ml IL-10 in RA patients with active disease (multiple inflammatory joints, CRP level ≥ 10 mg/l) and inactive disease (in remission, CRP level < 10 mg/l) [26] and in healthy controls.
T98 1281-1673 Sentence denotes There were no statistically significant differences in IFN-γ production without IL-10 among these three groups (Fig. 2a), but the inhibitory effect of IL-10 on IFN-γ production was significantly limited in the active RA group as compared with the inactive RA group and healthy controls (percentage decrease: active RA, 2.9 ± 14.4%; inactive RA, 45.6 ± 14.4%; controls, 65.8 ± 7.9%) (Fig. 2b).
T99 1674-1833 Sentence denotes As a consequence, CD4+ T cells from active RA patients produced higher levels of IFN-γ in the presence of 1 ng/ml IL-10 than did normal CD4+ T cells (Fig. 2a).
T100 1834-1995 Sentence denotes In addition, we compared IL-2 production by CD4+ T cells after CD3 and CD28 costimulation in the presence of IL-10 in active RA patients and in healthy controls.
T101 1996-2189 Sentence denotes Similarly, IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease, -2.1 ± 13.8%), while it was significantly reduced in healthy controls (61.1 ± 13.7%; P < 0.05).
T102 2190-2338 Sentence denotes Taken together, these results indicate that RA CD4+ T cells become less susceptible to the immunoregulatory effect of IL-10 during the active phase.
T103 2340-2403 Sentence denotes Increased expression of cell surface IL-10R1 on RA CD4+ T cells
T104 2404-2562 Sentence denotes The functional receptor complex of IL-10 consists of two subunits, the primary ligand-binding component IL-10R1 and the accessory component type 2 IL-10R [1].
T105 2563-2640 Sentence denotes IL-10R1 expression plays a critical role in cellular responses to IL-10 [29].
T106 2641-2905 Sentence denotes To examine whether the resistance to IL-10 inhibition in RA CD4+ T cells was due to limited receptor expression, the cell surface expression of IL-10R1 on PB CD4+ T cells from active RA patients and from healthy controls was determined by flow cytometric analysis.
T107 2906-3059 Sentence denotes As shown in Fig. 3a,3b, the intensity of IL-10R1 expression on CD4+ T cells was significantly increased in RA patients compared with in healthy controls.
T108 3060-3187 Sentence denotes These results suggest that the intracellular signal transduction pathway of IL-10 may be impaired in CD4+ T cells of active RA.
T109 3189-3254 Sentence denotes Defective IL-10-mediated STAT3 phosphorylation in RA CD4+ T cells
T110 3255-3396 Sentence denotes The interaction of IL-10R with IL-10 induces tyrosine phosphorylation and activation of the latent transcription factors STAT1 and STAT3 [3].
T111 3397-3648 Sentence denotes Macrophage-specific STAT3-deficient mice demonstrated that STAT3 plays a dominant role in IL-10-mediated anti-inflammatory responses [5], which has recently been confirmed in human macrophages by studies of dominant-negative STAT3 overexpression [30].
T112 3649-3812 Sentence denotes The induction of STAT1 and STAT3 phosphorylation by IL-10 in PB CD4+ T cells from active RA patients and from healthy controls was examined using western blotting.
T113 3813-3934 Sentence denotes STAT3 phosphorylation was dose-dependently induced after IL-10 activation for 20 min in normal CD4+ T cells (Fig. 4a,4b).
T114 3935-4088 Sentence denotes In contrast, STAT3 was phosphorylated in freshly isolated PB CD4+ cells from RA patients and this STAT3 phosphorylation was detectable for up to 6 hours.
T115 4089-4174 Sentence denotes STAT3 phosphorylation was augmented only when activated by as much as 10 ng/ml IL-10.
T116 4175-4305 Sentence denotes Both sustained STAT3 phosphorylation and defective IL-10-induced STAT3 phosphorylation were found in RA ST CD4+ T cells (Fig. 4c).
T117 4306-4437 Sentence denotes On the other hand, IL-10-induced STAT1 phosphorylation was not detected in either RA CD4+ T cells or normal CD4+ T cells (Fig. 4a).
T118 4438-4642 Sentence denotes These results indicate that STAT3 is the major IL-10-activated STAT in CD4+ T cells, and IL-10-induced STAT3 activation may be diminished in active RA, in association with sustained STAT3 phosphorylation.
T119 4644-4733 Sentence denotes IL-6-mediated STAT3 phosphorylation and inhibition of IL-10 effect in normal CD4+ T cells
T120 4734-5137 Sentence denotes STAT3 is activated by many cytokines and growth factors such as the IL-6 family of cytokines (IL-6, IL-11, leukemia inhibitory factor, and oncostatin M), platelet-derived growth factor, and epidermal growth factor, in addition to IL-10 [4], but previous studies have demonstrated that IL-6 is the major factor in RA synovial fluid that induces constitutive activation of STAT3 in mononuclear cells [31].
T121 5138-5449 Sentence denotes Since IL-6 is also abundant in sera of active RA patients, frequently detected at > 1 ng/ml [27], we examined whether persistent exposure of CD4+ T cells to high concentrations of IL-6 in the blood circulation was responsible for their sustained STAT3 activation and resistance to IL-10 inhibition in active RA.
T122 5450-5594 Sentence denotes Both STAT1 and STAT3 phosphorylation was activated by IL-6 in normal CD4+ T cells (data not shown), in agreement with previous observations [4].
T123 5595-5831 Sentence denotes Normal CD4+ T cells were thus incubated for 20 min with culture medium containing 30% serum from active RA patients and neutralizing anti-IL-6 antibody or control antibody, and STAT phosphorylation was examined by western blot analysis.
T124 5832-6001 Sentence denotes RA serum was able to induce tyrosine phosphorylation of STAT3 but not STAT1, and this STAT3 activation was mostly abolished by neutralization of IL-6 activity (Fig. 5a).
T125 6002-6115 Sentence denotes These results indicate that IL-6 is the dominant STAT3-activating factor contained in sera of active RA patients.
T126 6116-6343 Sentence denotes The lack of STAT1 activation by RA serum suggests that much higher concentrations of IL-6 may be required for STAT1 activation as compared with STAT3 activation, or that inhibitors of STAT1 signaling may be present in RA serum.
T127 6344-6453 Sentence denotes We next examined whether IL-6 could suppress the effect of IL-10 to inhibit IFN-γ production by CD4+ T cells.
T128 6454-6689 Sentence denotes After preincubation with or without 10 ng/ml IL-6 for 36 hours, normal CD4+ T cells were stimulated by CD3 and CD28 costimulation in the presence or absence of 1 ng/ml IL-10 for 36 hours, and the IFN-γ production was measured by ELISA.
T129 6690-6879 Sentence denotes IL-6 pretreatment of normal cells reduced IL-10-mediated inhibition of IFN-γ production (Fig. 5b), indicating that high concentrations of IL-6 could modulate T-cell responsiveness to IL-10.
T130 6880-7088 Sentence denotes Taken together, these findings suggest that persistent exposure to serum IL-6 may have a role in both the induction of STAT3 activation and the resistance to the inhibitory effect of IL-10 in RA CD4+ T cells.
T131 7090-7138 Sentence denotes High expression of SOCS1 mRNA in RA CD4+ T cells
T132 7139-7374 Sentence denotes IL-6 induces two potent inhibitors of JAKs (SOCS1 and SOCS3 proteins) that not only act as mediators of negative feedback inhibition, but also play a major role in crosstalk inhibition by opposing other cytokine-signaling pathways [7].
T133 7375-7544 Sentence denotes SOCS3 has recently been shown to specifically inhibit STAT3 activation induced by IL-6 but not by IL-10, thereby regulating the divergent action of IL-6 and IL-10 [8,9].
T134 7545-7701 Sentence denotes On the contrary, SOCS1 is able to partially inhibit IL-10-mediated STAT3 activation and cellular responses, as well as IFN-γ-mediated STAT1 activation [32].
T135 7702-7974 Sentence denotes To determine whether SOCSs were involved in the defective IL-10-induced STAT3 activation of RA CD4+ T cells, the levels of SOCS1 and SOCS3 mRNA expression in PB CD4+ T cells from active RA patients and from healthy controls were compared by semiquantitative real-time PCR.
T136 7975-8106 Sentence denotes The RA CD4+ T cells contained higher levels of SOCS1 but lower levels of SOCS3 transcripts than did control CD4+ T cells (Fig. 6a).
T137 8107-8300 Sentence denotes Constitutive expression of SOCS1 mRNA in RA CD4+ T cells was comparable with the expression in normal CD4+ T cells stimulated by 10 ng/ml IL-6 (Fig. 6b), supporting its functional significance.
T138 8301-8431 Sentence denotes Defective IL-10-induced STAT3 activation therefore appears to be due at least in part to an abundance of SOCS1 in RA CD4+ T cells.

simple1

Id Subject Object Predicate Lexical cue
T20672 8418-8421 Protein denotes CD4
T20671 8406-8411 Protein denotes SOCS1
T20670 8325-8330 Protein denotes STAT3
T20669 8311-8316 Protein denotes IL-10
T20668 8245-8249 Protein denotes IL-6
T20667 8209-8212 Protein denotes CD4
T20666 8151-8154 Protein denotes CD4
T20665 8134-8139 Protein denotes SOCS1
T20664 8083-8086 Protein denotes CD4
T20663 8048-8053 Protein denotes SOCS3
T20662 8022-8027 Protein denotes SOCS1
T20661 7982-7985 Protein denotes CD4
T20660 7863-7866 Protein denotes CD4
T20659 7835-7840 Protein denotes SOCS3
T20658 7825-7830 Protein denotes SOCS1
T20657 7797-7800 Protein denotes CD4
T20656 7774-7779 Protein denotes STAT3
T20655 7760-7765 Protein denotes IL-10
T20654 7679-7684 Protein denotes STAT1
T20653 7664-7669 Protein denotes IFN-γ
T20652 7612-7617 Protein denotes STAT3
T20651 7597-7602 Protein denotes IL-10
T20650 7562-7567 Protein denotes SOCS1
T20649 7532-7537 Protein denotes IL-10
T20648 7523-7527 Protein denotes IL-6
T20647 7473-7478 Protein denotes IL-10
T20646 7457-7461 Protein denotes IL-6
T20645 7429-7434 Protein denotes STAT3
T20644 7375-7380 Protein denotes SOCS3
T20643 7193-7198 Protein denotes SOCS3
T20642 7183-7188 Protein denotes SOCS1
T20641 7139-7143 Protein denotes IL-6
T20640 7126-7129 Protein denotes CD4
T20639 7109-7114 Protein denotes SOCS1
T18494 7075-7078 Protein denotes CD4
T18493 7063-7068 Protein denotes IL-10
T18492 6999-7004 Protein denotes STAT3
T18491 6953-6957 Protein denotes IL-6
T18490 6873-6878 Protein denotes IL-10
T18489 6828-6832 Protein denotes IL-6
T18488 6761-6766 Protein denotes IFN-γ
T18487 6732-6737 Protein denotes IL-10
T18486 6690-6694 Protein denotes IL-6
T18485 6650-6655 Protein denotes IFN-γ
T18484 6622-6627 Protein denotes IL-10
T18483 6565-6569 Protein denotes CD28
T18482 6525-6528 Protein denotes CD4
T18481 6499-6503 Protein denotes IL-6
T18480 6440-6443 Protein denotes CD4
T18479 6420-6425 Protein denotes IFN-γ
T18478 6403-6408 Protein denotes IL-10
T18477 6369-6373 Protein denotes IL-6
T18476 6300-6305 Protein denotes STAT1
T18475 6260-6265 Protein denotes STAT3
T18474 6226-6231 Protein denotes STAT1
T18473 6201-6205 Protein denotes IL-6
T18472 6128-6133 Protein denotes STAT1
T18471 6051-6056 Protein denotes STAT3
T18470 6030-6034 Protein denotes IL-6
T18469 5977-5981 Protein denotes IL-6
T18468 5918-5923 Protein denotes STAT3
T18467 5902-5907 Protein denotes STAT1
T18466 5888-5893 Protein denotes STAT3
T18465 5733-5737 Protein denotes IL-6
T18464 5602-5605 Protein denotes CD4
T18463 5519-5522 Protein denotes CD4
T18462 5504-5508 Protein denotes IL-6
T18461 5465-5470 Protein denotes STAT3
T18460 5455-5460 Protein denotes STAT1
T18459 5419-5424 Protein denotes IL-10
T18458 5384-5389 Protein denotes STAT3
T18457 5318-5322 Protein denotes IL-6
T18456 5279-5282 Protein denotes CD4
T18455 5144-5148 Protein denotes IL-6
T18454 5105-5110 Protein denotes STAT3
T18453 5019-5023 Protein denotes IL-6
T18452 4964-4969 Protein denotes IL-10
T18451 4924-4947 Protein denotes epidermal growth factor
T18450 4888-4918 Protein denotes platelet-derived growth factor
T18449 4873-4885 Protein denotes oncostatin M
T18448 4841-4867 Protein denotes leukemia inhibitory factor
T18447 4834-4839 Protein denotes IL-11
T18446 4828-4832 Protein denotes IL-6
T18445 4734-4739 Protein denotes STAT3
T18444 4721-4724 Protein denotes CD4
T18443 4698-4703 Protein denotes IL-10
T18442 4658-4663 Protein denotes STAT3
T18441 4644-4648 Protein denotes IL-6
T16193 4620-4625 Protein denotes STAT3
T16192 4541-4546 Protein denotes STAT3
T16191 4527-4532 Protein denotes IL-10
T16190 4509-4512 Protein denotes CD4
T16189 4485-4490 Protein denotes IL-10
T16188 4466-4471 Protein denotes STAT3
T16187 4414-4417 Protein denotes CD4
T16186 4391-4394 Protein denotes CD4
T16185 4339-4344 Protein denotes STAT1
T16184 4325-4330 Protein denotes IL-10
T16183 4282-4285 Protein denotes CD4
T16182 4240-4245 Protein denotes STAT3
T16181 4226-4231 Protein denotes IL-10
T16180 4190-4195 Protein denotes STAT3
T16179 4168-4173 Protein denotes IL-10
T16178 4089-4094 Protein denotes STAT3
T16177 4033-4038 Protein denotes STAT3
T16176 3996-3999 Protein denotes CD4
T16175 3948-3953 Protein denotes STAT3
T16174 3908-3911 Protein denotes CD4
T16173 3870-3875 Protein denotes IL-10
T16172 3813-3818 Protein denotes STAT3
T16171 3713-3716 Protein denotes CD4
T16170 3701-3706 Protein denotes IL-10
T16169 3676-3681 Protein denotes STAT3
T16168 3666-3671 Protein denotes STAT1
T16167 3622-3627 Protein denotes STAT3
T16166 3487-3492 Protein denotes IL-10
T16165 3456-3461 Protein denotes STAT3
T16164 3417-3422 Protein denotes STAT3
T16163 3386-3391 Protein denotes STAT3
T16162 3376-3381 Protein denotes STAT1
T16161 3286-3291 Protein denotes IL-10
T16160 3274-3280 Protein denotes IL-10R
T16159 3242-3245 Protein denotes CD4
T16158 3214-3219 Protein denotes STAT3
T16157 3199-3204 Protein denotes IL-10
T14854 3161-3164 Protein denotes CD4
T14853 3136-3141 Protein denotes IL-10
T14852 2969-2972 Protein denotes CD4
T14851 2947-2954 Protein denotes IL-10R1
T14850 2799-2802 Protein denotes CD4
T14849 2785-2792 Protein denotes IL-10R1
T14848 2701-2704 Protein denotes CD4
T14847 2678-2683 Protein denotes IL-10
T14846 2629-2634 Protein denotes IL-10
T14845 2563-2570 Protein denotes IL-10R1
T14844 2544-2557 Protein denotes type 2 IL-10R
T14843 2508-2515 Protein denotes IL-10R1
T14842 2439-2444 Protein denotes IL-10
T14841 2391-2394 Protein denotes CD4
T14840 2377-2384 Protein denotes IL-10R1
T13138 1047-1050 Protein denotes CD3
T13137 1028-1031 Protein denotes CD4
T13136 1008-1013 Protein denotes IFN-γ
T13135 941-946 Protein denotes IL-10
T13134 887-892 Protein denotes IL-10
T13133 854-859 Protein denotes IFN-γ
T13132 797-800 Protein denotes CD4
T13131 778-783 Protein denotes IL-10
T13130 708-711 Protein denotes CD4
T13129 671-676 Protein denotes IFN-γ
T13128 611-616 Protein denotes IFN-γ
T13127 587-592 Protein denotes IL-10
T13126 531-535 Protein denotes CD28
T13125 509-512 Protein denotes CD3
T13124 393-396 Protein denotes CD4
T13123 374-379 Protein denotes IL-10
T13122 358-361 Protein denotes CD4
T13121 240-244 Protein denotes CD28
T13120 184-189 Protein denotes IL-10
T13119 83-87 Protein denotes CD28
T13118 66-69 Protein denotes CD4
T13117 43-48 Protein denotes IFN-γ
T13116 23-28 Protein denotes IL-10
T13156 2308-2313 Protein denotes IL-10
T13155 2237-2240 Protein denotes CD4
T13154 2051-2056 Protein denotes IL-10
T13153 2007-2011 Protein denotes IL-2
T13152 1943-1948 Protein denotes IL-10
T13151 1905-1909 Protein denotes CD28
T13150 1878-1881 Protein denotes CD4
T13149 1859-1863 Protein denotes IL-2
T13148 1810-1813 Protein denotes CD4
T13147 1788-1793 Protein denotes IL-10
T13146 1755-1760 Protein denotes IFN-γ
T13145 1692-1695 Protein denotes CD4
T13144 1441-1446 Protein denotes IFN-γ
T13143 1432-1437 Protein denotes IL-10
T13142 1361-1366 Protein denotes IL-10
T13141 1336-1341 Protein denotes IFN-γ
T13140 1101-1106 Protein denotes IL-10
T13139 1055-1059 Protein denotes CD28

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T21475 8393-8402 Localization denotes abundance
T21474 8331-8341 Positive_regulation denotes activation
T21473 8317-8324 Positive_regulation denotes induced
T21472 8366-8369 Positive_regulation denotes due
T21471 8301-8310 Negative_regulation denotes Defective
T21470 8120-8130 Transcription denotes expression
T21469 7766-7773 Positive_regulation denotes induced
T21468 7846-7856 Transcription denotes expression
T21467 7780-7790 Positive_regulation denotes activation
T21466 7685-7695 Positive_regulation denotes activation
T21465 7618-7628 Positive_regulation denotes activation
T21464 7589-7596 Negative_regulation denotes inhibit
T21463 7435-7445 Positive_regulation denotes activation
T21462 7421-7428 Negative_regulation denotes inhibit
T21461 7446-7453 Positive_regulation denotes induced
T21460 7090-7094 Positive_regulation denotes High
T21459 7095-7105 Transcription denotes expression
T21458 8418-8421 Protein denotes CD4
T21457 8406-8411 Protein denotes SOCS1
T21456 8325-8330 Protein denotes STAT3
T21455 8311-8316 Protein denotes IL-10
T21454 8245-8249 Protein denotes IL-6
T21453 8209-8212 Protein denotes CD4
T21452 8151-8154 Protein denotes CD4
T21451 8134-8139 Protein denotes SOCS1
T21450 8083-8086 Protein denotes CD4
T21449 8048-8053 Protein denotes SOCS3
T21448 8022-8027 Protein denotes SOCS1
T21447 7982-7985 Protein denotes CD4
T21446 7863-7866 Protein denotes CD4
T21445 7835-7840 Protein denotes SOCS3
T21444 7825-7830 Protein denotes SOCS1
T21443 7797-7800 Protein denotes CD4
T21442 7774-7779 Protein denotes STAT3
T21441 7760-7765 Protein denotes IL-10
T21440 7679-7684 Protein denotes STAT1
T21439 7664-7669 Protein denotes IFN-γ
T21438 7612-7617 Protein denotes STAT3
T21437 7597-7602 Protein denotes IL-10
T21436 7562-7567 Protein denotes SOCS1
T21435 7473-7478 Protein denotes IL-10
T21434 7457-7461 Protein denotes IL-6
T21433 7429-7434 Protein denotes STAT3
T21432 7375-7380 Protein denotes SOCS3
T21431 7532-7537 Protein denotes IL-10
T21430 7523-7527 Protein denotes IL-6
T21429 7193-7198 Protein denotes SOCS3
T21428 7183-7188 Protein denotes SOCS1
T21427 7139-7143 Protein denotes IL-6
T21426 7126-7129 Protein denotes CD4
T21425 7109-7114 Protein denotes SOCS1
T19832 6051-6056 Protein denotes STAT3
T19831 6030-6034 Protein denotes IL-6
T19830 5977-5981 Protein denotes IL-6
T19829 5918-5923 Protein denotes STAT3
T19828 5902-5907 Protein denotes STAT1
T19827 5888-5893 Protein denotes STAT3
T19826 5733-5737 Protein denotes IL-6
T19825 5602-5605 Protein denotes CD4
T19824 5519-5522 Protein denotes CD4
T19823 5504-5508 Protein denotes IL-6
T19822 5465-5470 Protein denotes STAT3
T19821 5455-5460 Protein denotes STAT1
T19820 5419-5424 Protein denotes IL-10
T19819 5384-5389 Protein denotes STAT3
T19818 5318-5322 Protein denotes IL-6
T19817 5279-5282 Protein denotes CD4
T19816 5144-5148 Protein denotes IL-6
T19815 4873-4885 Protein denotes oncostatin M
T19814 4841-4867 Protein denotes leukemia inhibitory factor
T19813 4834-4839 Protein denotes IL-11
T19812 4828-4832 Protein denotes IL-6
T19811 4734-4739 Protein denotes STAT3
T19810 5105-5110 Protein denotes STAT3
T19809 5019-5023 Protein denotes IL-6
T19808 4964-4969 Protein denotes IL-10
T19807 4924-4947 Protein denotes epidermal growth factor
T19806 4888-4918 Protein denotes platelet-derived growth factor
T19805 4721-4724 Protein denotes CD4
T19804 4698-4703 Protein denotes IL-10
T19803 4658-4663 Protein denotes STAT3
T19802 4644-4648 Protein denotes IL-6
T19885 7005-7015 Positive_regulation denotes activation
T19884 6986-6995 Positive_regulation denotes induction
T19883 6767-6777 Gene_expression denotes production
T19882 6747-6757 Negative_regulation denotes inhibition
T19881 6656-6666 Gene_expression denotes production
T19880 6426-6436 Gene_expression denotes production
T19879 6412-6419 Negative_regulation denotes inhibit
T19878 6232-6242 Positive_regulation denotes activation
T19877 6266-6276 Positive_regulation denotes activation
T19876 6120-6124 Negative_regulation denotes lack
T19875 6134-6144 Positive_regulation denotes activation
T19874 6213-6221 Positive_regulation denotes required
T19873 5924-5934 Positive_regulation denotes activation
T19872 5853-5859 Positive_regulation denotes induce
T19871 5959-5973 Negative_regulation denotes neutralization
T19870 5869-5884 Phosphorylation denotes phosphorylation
T19869 5946-5955 Negative_regulation denotes abolished
T19868 5471-5486 Phosphorylation denotes phosphorylation
T19867 5491-5500 Positive_regulation denotes activated
T19866 5425-5435 Negative_regulation denotes inhibition
T19865 5352-5363 Positive_regulation denotes responsible
T19864 5390-5400 Positive_regulation denotes activation
T19863 5208-5216 Gene_expression denotes detected
T19862 5070-5077 Positive_regulation denotes induces
T19861 5091-5101 Positive_regulation denotes activation
T19860 4743-4752 Positive_regulation denotes activated
T19859 4704-4710 Regulation denotes effect
T19858 4649-4657 Positive_regulation denotes mediated
T19857 4684-4694 Negative_regulation denotes inhibition
T19856 4664-4679 Phosphorylation denotes phosphorylation
T19855 7075-7078 Protein denotes CD4
T19854 7063-7068 Protein denotes IL-10
T19853 6999-7004 Protein denotes STAT3
T19852 6953-6957 Protein denotes IL-6
T19851 6873-6878 Protein denotes IL-10
T19850 6828-6832 Protein denotes IL-6
T19849 6761-6766 Protein denotes IFN-γ
T19848 6732-6737 Protein denotes IL-10
T19847 6690-6694 Protein denotes IL-6
T19846 6650-6655 Protein denotes IFN-γ
T19845 6622-6627 Protein denotes IL-10
T19844 6565-6569 Protein denotes CD28
T19843 6525-6528 Protein denotes CD4
T19842 6499-6503 Protein denotes IL-6
T19841 6440-6443 Protein denotes CD4
T19840 6420-6425 Protein denotes IFN-γ
T19839 6403-6408 Protein denotes IL-10
T19838 6369-6373 Protein denotes IL-6
T19837 6300-6305 Protein denotes STAT1
T19836 6260-6265 Protein denotes STAT3
T19835 6226-6231 Protein denotes STAT1
T19834 6201-6205 Protein denotes IL-6
T19833 6128-6133 Protein denotes STAT1
T17086 4533-4540 Positive_regulation denotes induced
T17085 4610-4619 Positive_regulation denotes sustained
T17084 4565-4575 Negative_regulation denotes diminished
T17083 4547-4557 Positive_regulation denotes activation
T17082 4626-4641 Phosphorylation denotes phosphorylation
T17081 4345-4360 Phosphorylation denotes phosphorylation
T17080 4331-4338 Positive_regulation denotes induced
T17079 4246-4261 Phosphorylation denotes phosphorylation
T17078 4216-4225 Negative_regulation denotes defective
T17077 4196-4211 Phosphorylation denotes phosphorylation
T17076 4232-4239 Positive_regulation denotes induced
T17075 4180-4189 Positive_regulation denotes sustained
T17074 4115-4124 Positive_regulation denotes augmented
T17073 4095-4110 Phosphorylation denotes phosphorylation
T17072 3958-3972 Phosphorylation denotes phosphorylated
T17071 4039-4054 Phosphorylation denotes phosphorylation
T17070 3876-3886 Positive_regulation denotes activation
T17069 3856-3863 Positive_regulation denotes induced
T17023 3242-3245 Protein denotes CD4
T17022 3214-3219 Protein denotes STAT3
T17021 3199-3204 Protein denotes IL-10
T15310 2955-2965 Gene_expression denotes expression
T15309 3000-3009 Positive_regulation denotes increased
T15308 2771-2781 Gene_expression denotes expression
T15307 2684-2694 Negative_regulation denotes inhibition
T15306 2571-2581 Gene_expression denotes expression
T15305 2350-2360 Gene_expression denotes expression
T15304 2340-2349 Positive_regulation denotes Increased
T15303 3161-3164 Protein denotes CD4
T15302 3136-3141 Protein denotes IL-10
T15301 2969-2972 Protein denotes CD4
T15300 2947-2954 Protein denotes IL-10R1
T15299 2701-2704 Protein denotes CD4
T15298 2678-2683 Protein denotes IL-10
T15297 2799-2802 Protein denotes CD4
T15296 2785-2792 Protein denotes IL-10R1
T15295 2629-2634 Protein denotes IL-10
T15294 2563-2570 Protein denotes IL-10R1
T15293 2544-2557 Protein denotes type 2 IL-10R
T15292 2508-2515 Protein denotes IL-10R1
T15291 2439-2444 Protein denotes IL-10
T15290 2391-2394 Protein denotes CD4
T15289 2377-2384 Protein denotes IL-10R1
T14405 2012-2022 Gene_expression denotes production
T14404 2031-2039 Regulation denotes affected
T14403 1864-1874 Gene_expression denotes production
T14402 1447-1457 Gene_expression denotes production
T14401 1342-1352 Gene_expression denotes production
T14400 1014-1024 Gene_expression denotes production
T14399 823-830 Gene_expression denotes produce
T14398 732-741 Negative_regulation denotes inhibited
T14397 677-687 Gene_expression denotes production
T14396 617-627 Gene_expression denotes production
T14395 254-269 Phosphorylation denotes phosphorylation
T14394 229-239 Negative_regulation denotes inhibiting
T14393 29-39 Negative_regulation denotes inhibition
T14392 49-59 Gene_expression denotes production
T14391 2308-2313 Protein denotes IL-10
T14390 2237-2240 Protein denotes CD4
T14389 2051-2056 Protein denotes IL-10
T14388 2007-2011 Protein denotes IL-2
T14387 1943-1948 Protein denotes IL-10
T14386 1905-1909 Protein denotes CD28
T14385 1878-1881 Protein denotes CD4
T14384 1859-1863 Protein denotes IL-2
T14383 1810-1813 Protein denotes CD4
T14382 1788-1793 Protein denotes IL-10
T14381 1755-1760 Protein denotes IFN-γ
T14380 1692-1695 Protein denotes CD4
T14379 1441-1446 Protein denotes IFN-γ
T14378 1432-1437 Protein denotes IL-10
T14377 1361-1366 Protein denotes IL-10
T14376 1336-1341 Protein denotes IFN-γ
T14375 1101-1106 Protein denotes IL-10
T14351 23-28 Protein denotes IL-10
T14374 1055-1059 Protein denotes CD28
T14373 1047-1050 Protein denotes CD3
T14372 1028-1031 Protein denotes CD4
T14371 1008-1013 Protein denotes IFN-γ
T14370 941-946 Protein denotes IL-10
T14369 887-892 Protein denotes IL-10
T14368 854-859 Protein denotes IFN-γ
T14367 797-800 Protein denotes CD4
T14366 778-783 Protein denotes IL-10
T14365 708-711 Protein denotes CD4
T14364 671-676 Protein denotes IFN-γ
T14363 393-396 Protein denotes CD4
T14362 374-379 Protein denotes IL-10
T14361 358-361 Protein denotes CD4
T14360 611-616 Protein denotes IFN-γ
T14359 587-592 Protein denotes IL-10
T14358 531-535 Protein denotes CD28
T14357 509-512 Protein denotes CD3
T14356 240-244 Protein denotes CD28
T14355 184-189 Protein denotes IL-10
T14354 83-87 Protein denotes CD28
T14353 66-69 Protein denotes CD4
T14352 43-48 Protein denotes IFN-γ
T17048 4325-4330 Protein denotes IL-10
T17047 4282-4285 Protein denotes CD4
T17046 4240-4245 Protein denotes STAT3
T17045 4226-4231 Protein denotes IL-10
T17044 4190-4195 Protein denotes STAT3
T17043 4168-4173 Protein denotes IL-10
T17042 4089-4094 Protein denotes STAT3
T17041 4033-4038 Protein denotes STAT3
T17040 3996-3999 Protein denotes CD4
T17039 3948-3953 Protein denotes STAT3
T17038 3908-3911 Protein denotes CD4
T17037 3870-3875 Protein denotes IL-10
T17036 3813-3818 Protein denotes STAT3
T17035 3713-3716 Protein denotes CD4
T17034 3701-3706 Protein denotes IL-10
T17033 3676-3681 Protein denotes STAT3
T17032 3666-3671 Protein denotes STAT1
T17031 3456-3461 Protein denotes STAT3
T17030 3417-3422 Protein denotes STAT3
T17029 3622-3627 Protein denotes STAT3
T17028 3487-3492 Protein denotes IL-10
T17027 3386-3391 Protein denotes STAT3
T17026 3376-3381 Protein denotes STAT1
T17025 3286-3291 Protein denotes IL-10
T17024 3274-3280 Protein denotes IL-10R
T17068 3819-3834 Phosphorylation denotes phosphorylation
T17067 3682-3697 Phosphorylation denotes phosphorylation
T17066 3653-3662 Positive_regulation denotes induction
T17065 3423-3432 Negative_regulation denotes deficient
T17064 3628-3642 Gene_expression denotes overexpression
T17063 3259-3270 Binding denotes interaction
T17062 3292-3299 Positive_regulation denotes induces
T17061 3329-3339 Positive_regulation denotes activation
T17060 3220-3235 Phosphorylation denotes phosphorylation
T17059 3205-3213 Positive_regulation denotes mediated
T17058 3189-3198 Negative_regulation denotes Defective
T17057 4620-4625 Protein denotes STAT3
T17056 4541-4546 Protein denotes STAT3
T17055 4527-4532 Protein denotes IL-10
T17054 4509-4512 Protein denotes CD4
T17053 4485-4490 Protein denotes IL-10
T17052 4466-4471 Protein denotes STAT3
T17051 4414-4417 Protein denotes CD4
T17050 4391-4394 Protein denotes CD4
T17049 4339-4344 Protein denotes STAT1
R7409 T14352 T14392 themeOf IFN-γ,production
R7410 T14355 T14394 causeOf IL-10,inhibiting
R7411 T14356 T14395 themeOf CD28,phosphorylation
R7412 T14360 T14396 themeOf IFN-γ,production
R7413 T14364 T14397 themeOf IFN-γ,production
R7414 T14368 T14399 themeOf IFN-γ,produce
R7415 T14371 T14400 themeOf IFN-γ,production
R7416 T14376 T14401 themeOf IFN-γ,production
R7417 T14379 T14402 themeOf IFN-γ,production
R7418 T14384 T14403 themeOf IL-2,production
R7419 T14388 T14405 themeOf IL-2,production
R7420 T14392 T14393 themeOf production,inhibition
R7421 T14395 T14394 themeOf phosphorylation,inhibiting
R7422 T14397 T14398 themeOf production,inhibited
R7423 T14405 T14404 themeOf production,affected
R7793 T15289 T15305 themeOf IL-10R1,expression
R7794 T15294 T15306 themeOf IL-10R1,expression
R7795 T15296 T15308 themeOf IL-10R1,expression
R7796 T15298 T15307 themeOf IL-10,inhibition
R7797 T15300 T15310 themeOf IL-10R1,expression
R7798 T15305 T15304 themeOf expression,Increased
R7799 T15310 T15309 themeOf expression,increased
R8674 T17022 T17058 themeOf STAT3,Defective
R8675 T17022 T17059 themeOf STAT3,mediated
R8676 T17022 T17060 themeOf STAT3,phosphorylation
R8677 T17024 T17063 themeOf IL-10R,interaction
R8678 T17025 T17063 themeOf IL-10,interaction
R8679 T17026 T17061 themeOf STAT1,activation
R8680 T17027 T17061 themeOf STAT3,activation
R8681 T17029 T17064 themeOf STAT3,overexpression
R8682 T17030 T17065 themeOf STAT3,deficient
R8683 T17032 T17066 themeOf STAT1,induction
R8684 T17032 T17067 themeOf STAT1,phosphorylation
R8685 T17033 T17066 themeOf STAT3,induction
R8686 T17033 T17067 themeOf STAT3,phosphorylation
R8687 T17034 T17066 causeOf IL-10,induction
R8688 T17034 T17066 causeOf IL-10,induction
R8689 T17034 T17066 causeOf IL-10,induction
R8690 T17034 T17066 causeOf IL-10,induction
R8691 T17036 T17068 themeOf STAT3,phosphorylation
R8692 T17037 T17070 themeOf IL-10,activation
R8693 T17039 T17072 themeOf STAT3,phosphorylated
R8694 T17041 T17071 themeOf STAT3,phosphorylation
R8695 T17042 T17073 themeOf STAT3,phosphorylation
R8699 T17046 T17076 themeOf STAT3,induced
R8708 T17060 T17058 themeOf phosphorylation,Defective
R8709 T17060 T17059 themeOf phosphorylation,mediated
R8710 T17061 T17062 themeOf activation,induces
R8711 T17061 T17062 themeOf activation,induces
R8712 T17063 T17062 causeOf interaction,induces
R8713 T17063 T17062 causeOf interaction,induces
R8714 T17067 T17066 themeOf phosphorylation,induction
R8715 T17067 T17066 themeOf phosphorylation,induction
R8716 T17068 T17069 themeOf phosphorylation,induced
R10063 T19835 T19878 themeOf STAT1,activation
R10064 T19836 T19877 themeOf STAT3,activation
R10065 T19840 T19880 themeOf IFN-γ,production
R10066 T19846 T19881 themeOf IFN-γ,production
R10067 T19849 T19883 themeOf IFN-γ,production
R10068 T19853 T19885 themeOf STAT3,activation
R10071 T19861 T19862 themeOf activation,induces
R10072 T19864 T19865 themeOf activation,responsible
R10073 T19868 T19867 themeOf phosphorylation,activated
R10074 T19868 T19867 themeOf phosphorylation,activated
R10075 T19870 T19872 themeOf phosphorylation,induce
R10076 T19870 T19872 themeOf phosphorylation,induce
R10077 T19873 T19869 themeOf activation,abolished
R10078 T19875 T19876 themeOf activation,lack
R10079 T19878 T19874 themeOf activation,required
R10080 T19880 T19879 themeOf production,inhibit
R10081 T19883 T19882 themeOf production,inhibition
R10082 T19885 T19884 themeOf activation,induction
R10819 T21425 T21459 themeOf SOCS1,expression
R10820 T21433 T21463 themeOf STAT3,activation
R10821 T21433 T21461 themeOf STAT3,induced
R10822 T21438 T21465 themeOf STAT3,activation
R10823 T21440 T21466 themeOf STAT1,activation
R10824 T21442 T21467 themeOf STAT3,activation
R10825 T21444 T21468 themeOf SOCS1,expression
R10826 T21445 T21468 themeOf SOCS3,expression
R10827 T21451 T21470 themeOf SOCS1,expression
R10828 T21456 T21474 themeOf STAT3,activation
R10829 T21457 T21475 themeOf SOCS1,abundance
R10830 T21459 T21460 themeOf expression,High
R10831 T21463 T21462 themeOf activation,inhibit
R10832 T21463 T21461 themeOf activation,induced
R10833 T21465 T21464 themeOf activation,inhibit
R10834 T21466 T21464 themeOf activation,inhibit
R10835 T21467 T21469 themeOf activation,induced
R10836 T21474 T21472 themeOf activation,due
R10837 T21474 T21471 themeOf activation,Defective
R10838 T21474 T21473 themeOf activation,induced
R8717 T17073 T17074 themeOf phosphorylation,augmented
R8696 T17044 T17077 themeOf STAT3,phosphorylation
R8697 T17045 T17076 causeOf IL-10,induced
R8698 T17045 T17076 causeOf IL-10,induced
R8700 T17046 T17079 themeOf STAT3,phosphorylation
R8701 T17046 T17078 themeOf STAT3,defective
R8702 T17048 T17080 causeOf IL-10,induced
R8703 T17048 T17080 causeOf IL-10,induced
R8704 T17049 T17080 themeOf STAT1,induced
R8705 T17049 T17081 themeOf STAT1,phosphorylation
R8706 T17056 T17083 themeOf STAT3,activation
R8718 T17077 T17075 themeOf phosphorylation,sustained
R8719 T17079 T17076 themeOf phosphorylation,induced
R8720 T17079 T17078 themeOf phosphorylation,defective
R8721 T17081 T17080 themeOf phosphorylation,induced
R8723 T17083 T17086 themeOf activation,induced
R8707 T17057 T17082 themeOf STAT3,phosphorylation
R8722 T17082 T17085 themeOf phosphorylation,sustained
R8724 T17083 T17084 themeOf activation,diminished
R10039 T19803 T19858 themeOf STAT3,mediated
R10040 T19803 T19856 themeOf STAT3,phosphorylation
R10041 T19804 T19859 themeOf IL-10,effect
R10042 T19808 T19860 themeOf IL-10,activated
R10069 T19856 T19858 themeOf phosphorylation,mediated
R10070 T19859 T19857 themeOf effect,inhibition
R10043 T19810 T19861 themeOf STAT3,activation
R10044 T19811 T19860 themeOf STAT3,activated
R10045 T19814 T19860 causeOf leukemia inhibitory factor,activated
R10046 T19814 T19860 causeOf leukemia inhibitory factor,activated
R10047 T19816 T19863 themeOf IL-6,detected
R10048 T19819 T19864 themeOf STAT3,activation
R10049 T19820 T19866 themeOf IL-10,inhibition
R10050 T19821 T19868 themeOf STAT1,phosphorylation
R10051 T19821 T19867 themeOf STAT1,activated
R10052 T19822 T19868 themeOf STAT3,phosphorylation
R10053 T19822 T19867 themeOf STAT3,activated
R10054 T19823 T19867 causeOf IL-6,activated
R10055 T19823 T19867 causeOf IL-6,activated
R10056 T19823 T19867 causeOf IL-6,activated
R10057 T19823 T19867 causeOf IL-6,activated
R10058 T19827 T19870 themeOf STAT3,phosphorylation
R10059 T19828 T19870 themeOf STAT1,phosphorylation
R10060 T19829 T19873 themeOf STAT3,activation
R10061 T19830 T19871 themeOf IL-6,neutralization
R10062 T19833 T19875 themeOf STAT1,activation

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T20958 8317-8324 Positive_regulation denotes induced
T20913 7523-7527 Protein denotes IL-6
T20912 7193-7198 Protein denotes SOCS3
T20911 7183-7188 Protein denotes SOCS1
T20910 7139-7143 Protein denotes IL-6
T20909 7126-7129 Protein denotes CD4
T20908 7109-7114 Protein denotes SOCS1
T19004 6986-6995 Positive_regulation denotes induction
T19003 6969-6973 Regulation denotes role
T19002 7005-7015 Positive_regulation denotes activation
T19001 6738-6746 Positive_regulation denotes mediated
T18974 4649-4657 Positive_regulation denotes mediated
T18973 4684-4694 Negative_regulation denotes inhibition
T18972 4704-4710 Regulation denotes effect
T18971 4664-4679 Phosphorylation denotes phosphorylation
T18970 7075-7078 Protein denotes CD4
T18969 7063-7068 Protein denotes IL-10
T18968 6999-7004 Protein denotes STAT3
T18967 6953-6957 Protein denotes IL-6
T18966 6873-6878 Protein denotes IL-10
T18965 6828-6832 Protein denotes IL-6
T18964 6761-6766 Protein denotes IFN-γ
T18963 6732-6737 Protein denotes IL-10
T18962 6690-6694 Protein denotes IL-6
T18961 6650-6655 Protein denotes IFN-γ
T18960 6622-6627 Protein denotes IL-10
T18959 6565-6569 Protein denotes CD28
T18958 6525-6528 Protein denotes CD4
T18957 6499-6503 Protein denotes IL-6
T18956 6440-6443 Protein denotes CD4
T18955 6420-6425 Protein denotes IFN-γ
T18954 6403-6408 Protein denotes IL-10
T18953 6369-6373 Protein denotes IL-6
T18952 6300-6305 Protein denotes STAT1
T18951 6260-6265 Protein denotes STAT3
T18950 6226-6231 Protein denotes STAT1
T18949 6201-6205 Protein denotes IL-6
T18948 6128-6133 Protein denotes STAT1
T18947 6051-6056 Protein denotes STAT3
T18946 6030-6034 Protein denotes IL-6
T18945 5977-5981 Protein denotes IL-6
T18944 5918-5923 Protein denotes STAT3
T18943 5902-5907 Protein denotes STAT1
T18942 5888-5893 Protein denotes STAT3
T18941 5733-5737 Protein denotes IL-6
T18940 5602-5605 Protein denotes CD4
T18939 5519-5522 Protein denotes CD4
T18938 5504-5508 Protein denotes IL-6
T18937 5465-5470 Protein denotes STAT3
T18936 5455-5460 Protein denotes STAT1
T18935 5419-5424 Protein denotes IL-10
T18934 5384-5389 Protein denotes STAT3
T18933 5318-5322 Protein denotes IL-6
T18932 5279-5282 Protein denotes CD4
T18931 5144-5148 Protein denotes IL-6
T18930 4873-4885 Protein denotes oncostatin M
T18929 4841-4867 Protein denotes leukemia inhibitory factor
T18928 4834-4839 Protein denotes IL-11
T18927 4828-4832 Protein denotes IL-6
T18926 4734-4739 Protein denotes STAT3
T18925 5105-5110 Protein denotes STAT3
T18924 5019-5023 Protein denotes IL-6
T18923 4964-4969 Protein denotes IL-10
T18922 4924-4947 Protein denotes epidermal growth factor
T18921 4888-4918 Protein denotes platelet-derived growth factor
T18920 4721-4724 Protein denotes CD4
T18919 4698-4703 Protein denotes IL-10
T18918 4658-4663 Protein denotes STAT3
T18917 4644-4648 Protein denotes IL-6
T16493 4565-4575 Negative_regulation denotes diminished
T16492 4533-4540 Positive_regulation denotes induced
T16491 4547-4557 Positive_regulation denotes activation
T16449 4089-4094 Protein denotes STAT3
T16448 4033-4038 Protein denotes STAT3
T16447 3996-3999 Protein denotes CD4
T16446 3948-3953 Protein denotes STAT3
T16445 3908-3911 Protein denotes CD4
T16444 3870-3875 Protein denotes IL-10
T16443 3813-3818 Protein denotes STAT3
T16442 3713-3716 Protein denotes CD4
T16441 3701-3706 Protein denotes IL-10
T16440 3676-3681 Protein denotes STAT3
T16439 3666-3671 Protein denotes STAT1
T16438 3456-3461 Protein denotes STAT3
T16437 3417-3422 Protein denotes STAT3
T16436 3622-3627 Protein denotes STAT3
T16435 3487-3492 Protein denotes IL-10
T16434 3386-3391 Protein denotes STAT3
T16433 3376-3381 Protein denotes STAT1
T16432 3286-3291 Protein denotes IL-10
T16431 3274-3280 Protein denotes IL-10R
T16430 3242-3245 Protein denotes CD4
T16429 3214-3219 Protein denotes STAT3
T16428 3199-3204 Protein denotes IL-10
T15038 3149-3157 Negative_regulation denotes impaired
T15037 2955-2965 Gene_expression denotes expression
T15036 3000-3009 Positive_regulation denotes increased
T15035 2684-2694 Negative_regulation denotes inhibition
T15034 2771-2781 Gene_expression denotes expression
T15033 2571-2581 Gene_expression denotes expression
T15032 2483-2497 Binding denotes ligand-binding
T15031 2350-2360 Gene_expression denotes expression
T15030 2340-2349 Positive_regulation denotes Increased
T15029 3161-3164 Protein denotes CD4
T15028 3136-3141 Protein denotes IL-10
T15027 2969-2972 Protein denotes CD4
T15026 2947-2954 Protein denotes IL-10R1
T15025 2701-2704 Protein denotes CD4
T15024 2678-2683 Protein denotes IL-10
T15023 2799-2802 Protein denotes CD4
T15022 2785-2792 Protein denotes IL-10R1
T15021 2629-2634 Protein denotes IL-10
T15020 2563-2570 Protein denotes IL-10R1
T15019 2544-2557 Protein denotes type 2 IL-10R
T15018 2508-2515 Protein denotes IL-10R1
T15017 2439-2444 Protein denotes IL-10
T15016 2391-2394 Protein denotes CD4
T15015 2377-2384 Protein denotes IL-10R1
T13642 2136-2143 Negative_regulation denotes reduced
T13641 2031-2039 Regulation denotes affected
T13640 2012-2022 Gene_expression denotes production
T13639 1864-1874 Gene_expression denotes production
T13638 1729-1737 Gene_expression denotes produced
T13637 1447-1457 Gene_expression denotes production
T13636 1342-1352 Gene_expression denotes production
T13635 1014-1024 Gene_expression denotes production
T13634 927-937 Negative_regulation denotes inhibition
T13633 823-830 Gene_expression denotes produce
T13632 677-687 Gene_expression denotes production
T13631 732-741 Negative_regulation denotes inhibited
T13630 617-627 Gene_expression denotes production
T13629 229-239 Negative_regulation denotes inhibiting
T13628 254-269 Phosphorylation denotes phosphorylation
T13627 49-59 Gene_expression denotes production
T13626 29-39 Negative_regulation denotes inhibition
T13625 2308-2313 Protein denotes IL-10
T13624 2237-2240 Protein denotes CD4
T13623 2051-2056 Protein denotes IL-10
T13622 2007-2011 Protein denotes IL-2
T13621 1943-1948 Protein denotes IL-10
T13620 1905-1909 Protein denotes CD28
T13619 1878-1881 Protein denotes CD4
T13618 1859-1863 Protein denotes IL-2
T13617 1810-1813 Protein denotes CD4
T13616 1788-1793 Protein denotes IL-10
T13615 1755-1760 Protein denotes IFN-γ
T13614 1692-1695 Protein denotes CD4
T13613 1441-1446 Protein denotes IFN-γ
T13612 1432-1437 Protein denotes IL-10
T13611 1361-1366 Protein denotes IL-10
T13610 1336-1341 Protein denotes IFN-γ
T13609 1101-1106 Protein denotes IL-10
T13608 1055-1059 Protein denotes CD28
T13607 1047-1050 Protein denotes CD3
T13606 1028-1031 Protein denotes CD4
T13605 1008-1013 Protein denotes IFN-γ
T13604 941-946 Protein denotes IL-10
T13603 887-892 Protein denotes IL-10
T13602 854-859 Protein denotes IFN-γ
T13601 797-800 Protein denotes CD4
T13600 778-783 Protein denotes IL-10
T13599 708-711 Protein denotes CD4
T13598 671-676 Protein denotes IFN-γ
T13597 393-396 Protein denotes CD4
T13596 374-379 Protein denotes IL-10
T13595 358-361 Protein denotes CD4
T13594 611-616 Protein denotes IFN-γ
T13593 587-592 Protein denotes IL-10
T13592 531-535 Protein denotes CD28
T13591 509-512 Protein denotes CD3
T13590 240-244 Protein denotes CD28
T13589 184-189 Protein denotes IL-10
T13588 83-87 Protein denotes CD28
T13587 66-69 Protein denotes CD4
T13586 43-48 Protein denotes IFN-γ
T13585 23-28 Protein denotes IL-10
T20917 7457-7461 Protein denotes IL-6
T20916 7429-7434 Protein denotes STAT3
T20915 7375-7380 Protein denotes SOCS3
T20914 7532-7537 Protein denotes IL-10
T16471 3423-3432 Negative_regulation denotes deficient
T16470 3329-3339 Positive_regulation denotes activation
T16469 3259-3270 Binding denotes interaction
T16468 3292-3299 Positive_regulation denotes induces
T16467 3189-3198 Negative_regulation denotes Defective
T16466 3220-3235 Phosphorylation denotes phosphorylation
T16465 3205-3213 Positive_regulation denotes mediated
T16464 4620-4625 Protein denotes STAT3
T16463 4541-4546 Protein denotes STAT3
T16462 4527-4532 Protein denotes IL-10
T16461 4509-4512 Protein denotes CD4
T16460 4485-4490 Protein denotes IL-10
T16459 4466-4471 Protein denotes STAT3
T16458 4414-4417 Protein denotes CD4
T16457 4391-4394 Protein denotes CD4
T16456 4339-4344 Protein denotes STAT1
T16455 4325-4330 Protein denotes IL-10
T16454 4282-4285 Protein denotes CD4
T16453 4240-4245 Protein denotes STAT3
T16452 4226-4231 Protein denotes IL-10
T16451 4190-4195 Protein denotes STAT3
T16450 4168-4173 Protein denotes IL-10
T16490 4626-4641 Phosphorylation denotes phosphorylation
T16489 4610-4619 Positive_regulation denotes sustained
T16488 4331-4338 Positive_regulation denotes induced
T16487 4345-4360 Phosphorylation denotes phosphorylation
T16486 4180-4189 Positive_regulation denotes sustained
T16485 4216-4225 Negative_regulation denotes defective
T16484 4246-4261 Phosphorylation denotes phosphorylation
T16483 4232-4239 Positive_regulation denotes induced
T16482 4196-4211 Phosphorylation denotes phosphorylation
T16481 4095-4110 Phosphorylation denotes phosphorylation
T16480 4115-4124 Positive_regulation denotes augmented
T16479 3958-3972 Phosphorylation denotes phosphorylated
T16478 4039-4054 Phosphorylation denotes phosphorylation
T16477 3876-3886 Positive_regulation denotes activation
T16476 3856-3863 Positive_regulation denotes induced
T16475 3819-3834 Phosphorylation denotes phosphorylation
T16474 3653-3662 Positive_regulation denotes induction
T16473 3682-3697 Phosphorylation denotes phosphorylation
T16472 3628-3642 Positive_regulation denotes overexpression
T18991 6232-6242 Positive_regulation denotes activation
T18990 6266-6276 Positive_regulation denotes activation
T18989 6120-6124 Negative_regulation denotes lack
T18988 5853-5859 Positive_regulation denotes induce
T18987 5946-5955 Negative_regulation denotes abolished
T18986 5869-5884 Phosphorylation denotes phosphorylation
T18985 5924-5934 Positive_regulation denotes activation
T18984 5959-5973 Negative_regulation denotes neutralization
T18983 5471-5486 Phosphorylation denotes phosphorylation
T18982 5491-5500 Positive_regulation denotes activated
T18981 5352-5363 Positive_regulation denotes responsible
T18980 5425-5435 Negative_regulation denotes inhibition
T18979 5374-5383 Positive_regulation denotes sustained
T18978 5390-5400 Positive_regulation denotes activation
T18977 4743-4752 Positive_regulation denotes activated
T18976 5070-5077 Positive_regulation denotes induces
T18975 5091-5101 Positive_regulation denotes activation
T19000 6747-6757 Negative_regulation denotes inhibition
T18999 6767-6777 Gene_expression denotes production
T18998 6724-6731 Negative_regulation denotes reduced
T18997 6656-6666 Gene_expression denotes production
T18996 6393-6399 Regulation denotes effect
T18995 6412-6419 Negative_regulation denotes inhibit
T18994 6426-6436 Gene_expression denotes production
T18993 6134-6144 Positive_regulation denotes activation
T18992 6213-6221 Positive_regulation denotes required
T20957 8331-8341 Positive_regulation denotes activation
T20956 8366-8369 Positive_regulation denotes due
T20955 8301-8310 Negative_regulation denotes Defective
T20954 8120-8130 Gene_expression denotes expression
T20953 8054-8065 Transcription denotes transcripts
T20952 7846-7856 Transcription denotes expression
T20951 7589-7596 Negative_regulation denotes inhibit
T20950 7670-7678 Positive_regulation denotes mediated
T20949 7685-7695 Positive_regulation denotes activation
T20948 7603-7611 Positive_regulation denotes mediated
T20947 7618-7628 Positive_regulation denotes activation
T20946 7421-7428 Negative_regulation denotes inhibit
T20945 7446-7453 Positive_regulation denotes induced
T20944 7435-7445 Positive_regulation denotes activation
T20943 7163-7173 Negative_regulation denotes inhibitors
T20942 7095-7105 Gene_expression denotes expression
T20941 8418-8421 Protein denotes CD4
T20940 8406-8411 Protein denotes SOCS1
T20939 8325-8330 Protein denotes STAT3
T20938 8311-8316 Protein denotes IL-10
T20937 8245-8249 Protein denotes IL-6
T20936 8209-8212 Protein denotes CD4
T20935 8151-8154 Protein denotes CD4
T20934 8134-8139 Protein denotes SOCS1
T20933 8083-8086 Protein denotes CD4
T20932 8048-8053 Protein denotes SOCS3
T20931 8022-8027 Protein denotes SOCS1
T20930 7982-7985 Protein denotes CD4
T20929 7863-7866 Protein denotes CD4
T20928 7835-7840 Protein denotes SOCS3
T20927 7825-7830 Protein denotes SOCS1
T20926 7797-7800 Protein denotes CD4
T20925 7774-7779 Protein denotes STAT3
T20924 7760-7765 Protein denotes IL-10
T20923 7679-7684 Protein denotes STAT1
T20922 7664-7669 Protein denotes IFN-γ
T20921 7612-7617 Protein denotes STAT3
T20920 7597-7602 Protein denotes IL-10
T20919 7562-7567 Protein denotes SOCS1
T20918 7473-7478 Protein denotes IL-10
R6855 T13586 T13627 themeOf IFN-γ,production
R6856 T13589 T13629 causeOf IL-10,inhibiting
R6857 T13590 T13628 themeOf CD28,phosphorylation
R6858 T13594 T13630 themeOf IFN-γ,production
R6859 T13598 T13632 themeOf IFN-γ,production
R6860 T13602 T13633 themeOf IFN-γ,produce
R6861 T13604 T13634 themeOf IL-10,inhibition
R6862 T13605 T13635 themeOf IFN-γ,production
R6863 T13610 T13636 themeOf IFN-γ,production
R6864 T13613 T13637 themeOf IFN-γ,production
R6865 T13615 T13638 themeOf IFN-γ,produced
R6866 T13618 T13639 themeOf IL-2,production
R6867 T13622 T13640 themeOf IL-2,production
R6868 T13627 T13626 themeOf production,inhibition
R6869 T13628 T13629 themeOf phosphorylation,inhibiting
R6870 T13632 T13631 themeOf production,inhibited
R6871 T13640 T13642 themeOf production,reduced
R6872 T13640 T13641 themeOf production,affected
R7603 T15015 T15031 themeOf IL-10R1,expression
R7604 T15018 T15032 themeOf IL-10R1,ligand-binding
R7605 T15020 T15033 themeOf IL-10R1,expression
R7606 T15022 T15034 themeOf IL-10R1,expression
R7607 T15024 T15035 themeOf IL-10,inhibition
R7608 T15026 T15037 themeOf IL-10R1,expression
R7609 T15028 T15038 themeOf IL-10,impaired
R7610 T15031 T15030 themeOf expression,Increased
R7611 T15037 T15036 themeOf expression,increased
R8239 T16428 T16465 causeOf IL-10,mediated
R8240 T16429 T16466 themeOf STAT3,phosphorylation
R8241 T16431 T16469 themeOf IL-10R,interaction
R8242 T16432 T16469 themeOf IL-10,interaction
R8243 T16433 T16470 themeOf STAT1,activation
R8244 T16434 T16470 themeOf STAT3,activation
R8245 T16436 T16472 themeOf STAT3,overexpression
R8246 T16437 T16471 themeOf STAT3,deficient
R8247 T16439 T16474 themeOf STAT1,induction
R8248 T16439 T16473 themeOf STAT1,phosphorylation
R8249 T16440 T16474 themeOf STAT3,induction
R8250 T16440 T16473 themeOf STAT3,phosphorylation
R8251 T16441 T16474 causeOf IL-10,induction
R8252 T16441 T16474 causeOf IL-10,induction
R8253 T16443 T16475 themeOf STAT3,phosphorylation
R8254 T16444 T16477 themeOf IL-10,activation
R8255 T16446 T16479 themeOf STAT3,phosphorylated
R8256 T16448 T16478 themeOf STAT3,phosphorylation
R8257 T16449 T16481 themeOf STAT3,phosphorylation
R8258 T16451 T16482 themeOf STAT3,phosphorylation
R8259 T16452 T16483 causeOf IL-10,induced
R8260 T16453 T16484 themeOf STAT3,phosphorylation
R8261 T16455 T16488 causeOf IL-10,induced
R8262 T16456 T16487 themeOf STAT1,phosphorylation
R8263 T16462 T16492 causeOf IL-10,induced
R8264 T16463 T16491 themeOf STAT3,activation
R8265 T16464 T16490 themeOf STAT3,phosphorylation
R8266 T16466 T16467 themeOf phosphorylation,Defective
R8267 T16466 T16465 themeOf phosphorylation,mediated
R8268 T16469 T16468 causeOf interaction,induces
R8269 T16469 T16468 causeOf interaction,induces
R8270 T16470 T16468 themeOf activation,induces
R8271 T16470 T16468 themeOf activation,induces
R8272 T16475 T16476 themeOf phosphorylation,induced
R8273 T16477 T16476 causeOf activation,induced
R8274 T16481 T16480 themeOf phosphorylation,augmented
R8275 T16482 T16486 themeOf phosphorylation,sustained
R8276 T16484 T16483 themeOf phosphorylation,induced
R8277 T16484 T16485 themeOf phosphorylation,defective
R8278 T16487 T16488 themeOf phosphorylation,induced
R8279 T16490 T16489 themeOf phosphorylation,sustained
R8280 T16491 T16492 themeOf activation,induced
R8281 T16491 T16493 themeOf activation,diminished
R9398 T18917 T18974 causeOf IL-6,mediated
R9399 T18918 T18971 themeOf STAT3,phosphorylation
R9400 T18919 T18972 themeOf IL-10,effect
R9401 T18923 T18977 themeOf IL-10,activated
R9402 T18925 T18975 themeOf STAT3,activation
R9403 T18926 T18977 themeOf STAT3,activated
R9404 T18934 T18978 themeOf STAT3,activation
R9405 T18935 T18980 themeOf IL-10,inhibition
R9406 T18936 T18983 themeOf STAT1,phosphorylation
R9407 T18936 T18982 themeOf STAT1,activated
R9408 T18937 T18983 themeOf STAT3,phosphorylation
R9409 T18937 T18982 themeOf STAT3,activated
R9410 T18938 T18982 causeOf IL-6,activated
R9411 T18938 T18982 causeOf IL-6,activated
R9412 T18942 T18986 themeOf STAT3,phosphorylation
R9413 T18943 T18986 themeOf STAT1,phosphorylation
R9414 T18944 T18985 themeOf STAT3,activation
R9415 T18945 T18984 themeOf IL-6,neutralization
R9416 T18948 T18993 themeOf STAT1,activation
R9417 T18950 T18991 themeOf STAT1,activation
R9418 T18951 T18990 themeOf STAT3,activation
R9419 T18954 T18996 themeOf IL-10,effect
R9420 T18955 T18994 themeOf IFN-γ,production
R9421 T18961 T18997 themeOf IFN-γ,production
R9422 T18963 T19001 themeOf IL-10,mediated
R9423 T18964 T18999 themeOf IFN-γ,production
R9424 T18968 T19002 themeOf STAT3,activation
R9425 T18971 T18974 themeOf phosphorylation,mediated
R9426 T18972 T18973 themeOf effect,inhibition
R9427 T18975 T18976 themeOf activation,induces
R9428 T18978 T18981 themeOf activation,responsible
R9429 T18978 T18979 themeOf activation,sustained
R9430 T18985 T18987 themeOf activation,abolished
R9431 T18986 T18988 themeOf phosphorylation,induce
R9432 T18986 T18988 themeOf phosphorylation,induce
R9433 T18991 T18992 themeOf activation,required
R9434 T18993 T18989 themeOf activation,lack
R9435 T18994 T18995 themeOf production,inhibit
R9436 T18999 T19000 themeOf production,inhibition
R9437 T19000 T18998 themeOf inhibition,reduced
R9438 T19001 T18998 themeOf mediated,reduced
R9439 T19002 T19004 themeOf activation,induction
R9440 T19004 T19003 themeOf induction,role
R10458 T20908 T20942 themeOf SOCS1,expression
R10459 T20912 T20943 themeOf SOCS3,inhibitors
R10460 T20916 T20944 themeOf STAT3,activation
R10461 T20916 T20945 themeOf STAT3,induced
R10462 T20916 T20945 themeOf STAT3,induced
R10463 T20917 T20945 causeOf IL-6,induced
R10464 T20917 T20945 causeOf IL-6,induced
R10465 T20918 T20945 causeOf IL-10,induced
R10466 T20918 T20945 causeOf IL-10,induced
R10467 T20921 T20947 themeOf STAT3,activation
R10468 T20922 T20950 causeOf IFN-γ,mediated
R10469 T20923 T20949 themeOf STAT1,activation
R10470 T20927 T20952 themeOf SOCS1,expression
R10471 T20932 T20953 themeOf SOCS3,transcripts
R10472 T20934 T20954 themeOf SOCS1,expression
R10473 T20938 T20958 causeOf IL-10,induced
R10474 T20939 T20957 themeOf STAT3,activation
R10475 T20944 T20946 themeOf activation,inhibit
R10476 T20944 T20945 themeOf activation,induced
R10477 T20944 T20945 themeOf activation,induced
R10478 T20947 T20948 themeOf activation,mediated
R10479 T20949 T20951 themeOf activation,inhibit
R10480 T20949 T20950 themeOf activation,mediated
R10481 T20957 T20956 themeOf activation,due
R10482 T20957 T20955 themeOf activation,Defective
R10483 T20957 T20958 themeOf activation,induced

DLUT931

Id Subject Object Predicate Lexical cue
T21263 8366-8369 Positive_regulation denotes due
T21262 8393-8402 Gene_expression denotes abundance
T21261 8331-8341 Positive_regulation denotes activation
T21260 8107-8119 Positive_regulation denotes Constitutive
T21259 8120-8130 Gene_expression denotes expression
T21258 8054-8065 Transcription denotes transcripts
T21257 8005-8011 Positive_regulation denotes higher
T21256 7846-7856 Transcription denotes expression
T21255 7670-7678 Positive_regulation denotes mediated
T21254 7603-7611 Positive_regulation denotes mediated
T21253 7589-7596 Negative_regulation denotes inhibit
T21252 7685-7695 Positive_regulation denotes activation
T21251 7618-7628 Positive_regulation denotes activation
T21250 7421-7428 Negative_regulation denotes inhibit
T21249 7488-7498 Regulation denotes regulating
T21248 7446-7453 Positive_regulation denotes induced
T21247 7435-7445 Positive_regulation denotes activation
T21246 7144-7151 Positive_regulation denotes induces
T21245 7163-7173 Negative_regulation denotes inhibitors
T21244 7090-7094 Positive_regulation denotes High
T21243 7095-7105 Gene_expression denotes expression
T21242 8418-8421 Protein denotes CD4
T21241 8406-8411 Protein denotes SOCS1
T21240 8325-8330 Protein denotes STAT3
T21239 8311-8316 Protein denotes IL-10
T21238 8245-8249 Protein denotes IL-6
T21237 8209-8212 Protein denotes CD4
T21236 8151-8154 Protein denotes CD4
T21235 8134-8139 Protein denotes SOCS1
T21234 8083-8086 Protein denotes CD4
T21233 8048-8053 Protein denotes SOCS3
T21232 8022-8027 Protein denotes SOCS1
T21231 7982-7985 Protein denotes CD4
T21230 7863-7866 Protein denotes CD4
T21229 7835-7840 Protein denotes SOCS3
T21228 7825-7830 Protein denotes SOCS1
T21227 7797-7800 Protein denotes CD4
T21226 7774-7779 Protein denotes STAT3
T21225 7760-7765 Protein denotes IL-10
T21224 7679-7684 Protein denotes STAT1
T21223 7664-7669 Protein denotes IFN-γ
T21222 7612-7617 Protein denotes STAT3
T21221 7597-7602 Protein denotes IL-10
T21220 7562-7567 Protein denotes SOCS1
T21219 7473-7478 Protein denotes IL-10
T21218 7457-7461 Protein denotes IL-6
T21217 7429-7434 Protein denotes STAT3
T21216 7375-7380 Protein denotes SOCS3
T21215 7532-7537 Protein denotes IL-10
T21214 7523-7527 Protein denotes IL-6
T21213 7193-7198 Protein denotes SOCS3
T21212 7183-7188 Protein denotes SOCS1
T21211 7139-7143 Protein denotes IL-6
T21210 7126-7129 Protein denotes CD4
T21209 7109-7114 Protein denotes SOCS1
T19452 5019-5023 Protein denotes IL-6
T19451 4964-4969 Protein denotes IL-10
T19450 4924-4947 Protein denotes epidermal growth factor
T19449 4888-4918 Protein denotes platelet-derived growth factor
T19448 4721-4724 Protein denotes CD4
T19447 4698-4703 Protein denotes IL-10
T19446 4658-4663 Protein denotes STAT3
T19445 4644-4648 Protein denotes IL-6
T19537 6969-6973 Regulation denotes role
T19536 6986-6995 Positive_regulation denotes induction
T19535 7005-7015 Positive_regulation denotes activation
T19534 6738-6746 Positive_regulation denotes mediated
T19533 6724-6731 Negative_regulation denotes reduced
T19532 6839-6847 Regulation denotes modulate
T19531 6747-6757 Negative_regulation denotes inhibition
T19530 6855-6869 Positive_regulation denotes responsiveness
T19529 6767-6777 Gene_expression denotes production
T19528 6543-6553 Positive_regulation denotes stimulated
T19527 6656-6666 Gene_expression denotes production
T19526 6393-6399 Regulation denotes effect
T19525 6412-6419 Negative_regulation denotes inhibit
T19524 6426-6436 Gene_expression denotes production
T19523 6213-6221 Positive_regulation denotes required
T19522 6120-6124 Negative_regulation denotes lack
T19521 6286-6296 Negative_regulation denotes inhibitors
T19520 6266-6276 Positive_regulation denotes activation
T19519 6232-6242 Positive_regulation denotes activation
T19518 6134-6144 Positive_regulation denotes activation
T19517 6057-6067 Positive_regulation denotes activating
T19516 5853-5859 Positive_regulation denotes induce
T19515 5946-5955 Negative_regulation denotes abolished
T19514 5924-5934 Positive_regulation denotes activation
T19513 5869-5884 Phosphorylation denotes phosphorylation
T19512 5491-5500 Positive_regulation denotes activated
T19511 5471-5486 Phosphorylation denotes phosphorylation
T19510 5405-5415 Positive_regulation denotes resistance
T19509 5374-5383 Positive_regulation denotes sustained
T19508 5352-5363 Positive_regulation denotes responsible
T19507 5425-5435 Negative_regulation denotes inhibition
T19506 5390-5400 Positive_regulation denotes activation
T19505 5208-5216 Gene_expression denotes detected
T19504 5070-5077 Positive_regulation denotes induces
T19503 5091-5101 Positive_regulation denotes activation
T19502 4743-4752 Positive_regulation denotes activated
T19501 4649-4657 Positive_regulation denotes mediated
T19500 4704-4710 Regulation denotes effect
T19499 4664-4679 Phosphorylation denotes phosphorylation
T19498 7075-7078 Protein denotes CD4
T19497 7063-7068 Protein denotes IL-10
T19496 6999-7004 Protein denotes STAT3
T19492 6761-6766 Protein denotes IFN-γ
T19491 6732-6737 Protein denotes IL-10
T19490 6690-6694 Protein denotes IL-6
T19489 6650-6655 Protein denotes IFN-γ
T19488 6622-6627 Protein denotes IL-10
T19487 6565-6569 Protein denotes CD28
T19486 6525-6528 Protein denotes CD4
T19485 6499-6503 Protein denotes IL-6
T19484 6440-6443 Protein denotes CD4
T19483 6420-6425 Protein denotes IFN-γ
T19482 6403-6408 Protein denotes IL-10
T19481 6369-6373 Protein denotes IL-6
T19480 6300-6305 Protein denotes STAT1
T19479 6260-6265 Protein denotes STAT3
T19478 6226-6231 Protein denotes STAT1
T19477 6201-6205 Protein denotes IL-6
T19476 6128-6133 Protein denotes STAT1
T19475 6051-6056 Protein denotes STAT3
T19474 6030-6034 Protein denotes IL-6
T19473 5977-5981 Protein denotes IL-6
T19472 5918-5923 Protein denotes STAT3
T19471 5902-5907 Protein denotes STAT1
T19470 5888-5893 Protein denotes STAT3
T19469 5733-5737 Protein denotes IL-6
T19468 5602-5605 Protein denotes CD4
T19467 5519-5522 Protein denotes CD4
T19466 5504-5508 Protein denotes IL-6
T19465 5465-5470 Protein denotes STAT3
T19464 5455-5460 Protein denotes STAT1
T19463 5419-5424 Protein denotes IL-10
T19462 5384-5389 Protein denotes STAT3
T19461 5318-5322 Protein denotes IL-6
T19460 5279-5282 Protein denotes CD4
T19459 5144-5148 Protein denotes IL-6
T19458 4873-4885 Protein denotes oncostatin M
T19457 4841-4867 Protein denotes leukemia inhibitory factor
T19456 4834-4839 Protein denotes IL-11
T19455 4828-4832 Protein denotes IL-6
T19454 4734-4739 Protein denotes STAT3
T19453 5105-5110 Protein denotes STAT3
T16815 4610-4619 Positive_regulation denotes sustained
T16814 4533-4540 Positive_regulation denotes induced
T16813 4626-4641 Phosphorylation denotes phosphorylation
T16812 4593-4604 Binding denotes association
T16811 4565-4575 Negative_regulation denotes diminished
T16810 4547-4557 Positive_regulation denotes activation
T16809 4369-4377 Negative_regulation denotes detected
T16808 4331-4338 Positive_regulation denotes induced
T16807 4345-4360 Phosphorylation denotes phosphorylation
T16806 4232-4239 Positive_regulation denotes induced
T16805 4216-4225 Negative_regulation denotes defective
T16804 4180-4189 Positive_regulation denotes sustained
T16773 4339-4344 Protein denotes STAT1
T16772 4325-4330 Protein denotes IL-10
T16771 4282-4285 Protein denotes CD4
T16770 4240-4245 Protein denotes STAT3
T16769 4226-4231 Protein denotes IL-10
T16768 4190-4195 Protein denotes STAT3
T16767 4168-4173 Protein denotes IL-10
T16766 4089-4094 Protein denotes STAT3
T16765 4033-4038 Protein denotes STAT3
T16764 3996-3999 Protein denotes CD4
T16763 3948-3953 Protein denotes STAT3
T16762 3908-3911 Protein denotes CD4
T16761 3870-3875 Protein denotes IL-10
T16760 3813-3818 Protein denotes STAT3
T16759 3713-3716 Protein denotes CD4
T16758 3701-3706 Protein denotes IL-10
T16757 3676-3681 Protein denotes STAT3
T16756 3666-3671 Protein denotes STAT1
T16755 3456-3461 Protein denotes STAT3
T16754 3417-3422 Protein denotes STAT3
T16753 3622-3627 Protein denotes STAT3
T16752 3487-3492 Protein denotes IL-10
T16751 3386-3391 Protein denotes STAT3
T16750 3376-3381 Protein denotes STAT1
T16749 3286-3291 Protein denotes IL-10
T16748 3274-3280 Protein denotes IL-10R
T16747 3242-3245 Protein denotes CD4
T16746 3214-3219 Protein denotes STAT3
T16745 3199-3204 Protein denotes IL-10
T16803 4246-4261 Phosphorylation denotes phosphorylation
T16802 4196-4211 Phosphorylation denotes phosphorylation
T16801 4135-4144 Positive_regulation denotes activated
T16800 4115-4124 Positive_regulation denotes augmented
T16799 4095-4110 Phosphorylation denotes phosphorylation
T16798 4039-4054 Phosphorylation denotes phosphorylation
T16797 3958-3972 Phosphorylation denotes phosphorylated
T16796 3856-3863 Positive_regulation denotes induced
T16795 3876-3886 Positive_regulation denotes activation
T16794 3819-3834 Phosphorylation denotes phosphorylation
T16793 3682-3697 Phosphorylation denotes phosphorylation
T16792 3653-3662 Positive_regulation denotes induction
T16791 3604-3621 Negative_regulation denotes dominant-negative
T16790 3628-3642 Positive_regulation denotes overexpression
T16789 3493-3501 Positive_regulation denotes mediated
T16788 3423-3432 Negative_regulation denotes deficient
T16787 3292-3299 Positive_regulation denotes induces
T16786 3329-3339 Positive_regulation denotes activation
T16785 3259-3270 Binding denotes interaction
T16784 3205-3213 Positive_regulation denotes mediated
T16783 3189-3198 Negative_regulation denotes Defective
T16782 3220-3235 Phosphorylation denotes phosphorylation
T16781 4620-4625 Protein denotes STAT3
T16780 4541-4546 Protein denotes STAT3
T16779 4527-4532 Protein denotes IL-10
T16778 4509-4512 Protein denotes CD4
T16777 4485-4490 Protein denotes IL-10
T16776 4466-4471 Protein denotes STAT3
T16775 4414-4417 Protein denotes CD4
T16774 4391-4394 Protein denotes CD4
T15217 3000-3009 Positive_regulation denotes increased
T15216 2955-2965 Gene_expression denotes expression
T15215 2664-2674 Positive_regulation denotes resistance
T15214 2771-2781 Gene_expression denotes expression
T15213 2684-2694 Negative_regulation denotes inhibition
T15212 2571-2581 Gene_expression denotes expression
T15211 2483-2497 Binding denotes ligand-binding
T15210 2340-2349 Positive_regulation denotes Increased
T15209 2350-2360 Gene_expression denotes expression
T15208 3161-3164 Protein denotes CD4
T15207 3136-3141 Protein denotes IL-10
T15206 2969-2972 Protein denotes CD4
T15205 2947-2954 Protein denotes IL-10R1
T15204 2701-2704 Protein denotes CD4
T15203 2678-2683 Protein denotes IL-10
T15202 2799-2802 Protein denotes CD4
T15201 2785-2792 Protein denotes IL-10R1
T15200 2629-2634 Protein denotes IL-10
T15199 2563-2570 Protein denotes IL-10R1
T15198 2544-2557 Protein denotes type 2 IL-10R
T15197 2508-2515 Protein denotes IL-10R1
T15196 2439-2444 Protein denotes IL-10
T15195 2391-2394 Protein denotes CD4
T15194 2377-2384 Protein denotes IL-10R1
T14154 2031-2039 Regulation denotes affected
T14153 2012-2022 Gene_expression denotes production
T14152 1864-1874 Gene_expression denotes production
T14151 1738-1744 Positive_regulation denotes higher
T14150 1729-1737 Gene_expression denotes produced
T14149 1321-1332 Regulation denotes differences
T14148 1447-1457 Gene_expression denotes production
T14147 1422-1428 Regulation denotes effect
T14146 1342-1352 Gene_expression denotes production
T14145 1060-1073 Negative_regulation denotes costimulation
T14144 1014-1024 Gene_expression denotes production
T14143 927-937 Negative_regulation denotes inhibition
T14142 823-830 Gene_expression denotes produce
T14141 732-741 Negative_regulation denotes inhibited
T14140 691-700 Positive_regulation denotes activated
T14139 677-687 Gene_expression denotes production
T14138 617-627 Gene_expression denotes production
T14137 229-239 Negative_regulation denotes inhibiting
T14136 254-269 Phosphorylation denotes phosphorylation
T14135 9-19 Positive_regulation denotes Resistance
T14134 29-39 Negative_regulation denotes inhibition
T14133 49-59 Gene_expression denotes production
T14132 2308-2313 Protein denotes IL-10
T14131 2237-2240 Protein denotes CD4
T14130 2051-2056 Protein denotes IL-10
T14129 2007-2011 Protein denotes IL-2
T14128 1943-1948 Protein denotes IL-10
T14127 1905-1909 Protein denotes CD28
T14126 1878-1881 Protein denotes CD4
T14125 1859-1863 Protein denotes IL-2
T14124 1810-1813 Protein denotes CD4
T14123 1788-1793 Protein denotes IL-10
T14122 1755-1760 Protein denotes IFN-γ
T14121 1692-1695 Protein denotes CD4
T14120 1441-1446 Protein denotes IFN-γ
T14119 1432-1437 Protein denotes IL-10
T14118 1361-1366 Protein denotes IL-10
T14117 1336-1341 Protein denotes IFN-γ
T14116 1101-1106 Protein denotes IL-10
T14115 1055-1059 Protein denotes CD28
T14114 1047-1050 Protein denotes CD3
T14113 1028-1031 Protein denotes CD4
T14112 1008-1013 Protein denotes IFN-γ
T14111 941-946 Protein denotes IL-10
T14110 887-892 Protein denotes IL-10
T14109 854-859 Protein denotes IFN-γ
T14108 797-800 Protein denotes CD4
T14107 778-783 Protein denotes IL-10
T14106 708-711 Protein denotes CD4
T14105 671-676 Protein denotes IFN-γ
T14104 393-396 Protein denotes CD4
T14103 374-379 Protein denotes IL-10
T14102 358-361 Protein denotes CD4
T14101 611-616 Protein denotes IFN-γ
T14100 587-592 Protein denotes IL-10
T14099 531-535 Protein denotes CD28
T14098 509-512 Protein denotes CD3
T14097 240-244 Protein denotes CD28
T14096 184-189 Protein denotes IL-10
T14095 83-87 Protein denotes CD28
T14094 66-69 Protein denotes CD4
T14093 43-48 Protein denotes IFN-γ
T14092 23-28 Protein denotes IL-10
T19494 6873-6878 Protein denotes IL-10
T19493 6828-6832 Protein denotes IL-6
T19495 6953-6957 Protein denotes IL-6
R7322 T14092 T14135 causeOf IL-10,Resistance
R7323 T14093 T14133 themeOf IFN-γ,production
R7324 T14096 T14137 causeOf IL-10,inhibiting
R7325 T14097 T14136 themeOf CD28,phosphorylation
R7326 T14101 T14138 themeOf IFN-γ,production
R7327 T14105 T14139 themeOf IFN-γ,production
R7328 T14109 T14142 themeOf IFN-γ,produce
R7329 T14110 T14142 themeOf IL-10,produce
R7330 T14111 T14143 themeOf IL-10,inhibition
R7331 T14112 T14144 themeOf IFN-γ,production
R7332 T14114 T14145 themeOf CD3,costimulation
R7333 T14115 T14145 themeOf CD28,costimulation
R7334 T14117 T14146 themeOf IFN-γ,production
R7335 T14118 T14146 themeOf IL-10,production
R7336 T14119 T14147 themeOf IL-10,effect
R7337 T14119 T14148 themeOf IL-10,production
R7338 T14120 T14148 themeOf IFN-γ,production
R7339 T14122 T14150 themeOf IFN-γ,produced
R7340 T14122 T14151 themeOf IFN-γ,higher
R7341 T14125 T14152 themeOf IL-2,production
R7342 T14129 T14153 themeOf IL-2,production
R7343 T14130 T14154 causeOf IL-10,affected
R7344 T14133 T14134 themeOf production,inhibition
R7345 T14134 T14135 themeOf inhibition,Resistance
R7346 T14136 T14137 themeOf phosphorylation,inhibiting
R7347 T14139 T14140 themeOf production,activated
R7348 T14139 T14141 themeOf production,inhibited
R7349 T14146 T14149 themeOf production,differences
R7350 T14146 T14149 themeOf production,differences
R7351 T14148 T14147 themeOf production,effect
R7352 T14148 T14147 themeOf production,effect
R7353 T14150 T14151 themeOf produced,higher
R7354 T14153 T14154 themeOf production,affected
R7767 T15194 T15209 themeOf IL-10R1,expression
R7768 T15197 T15211 themeOf IL-10R1,ligand-binding
R7769 T15198 T15211 themeOf type 2 IL-10R,ligand-binding
R7770 T15199 T15212 themeOf IL-10R1,expression
R7771 T15201 T15214 themeOf IL-10R1,expression
R7772 T15203 T15213 themeOf IL-10,inhibition
R7773 T15205 T15216 themeOf IL-10R1,expression
R7774 T15209 T15210 themeOf expression,Increased
R7775 T15213 T15215 themeOf inhibition,resistance
R7776 T15216 T15217 themeOf expression,increased
R8533 T16745 T16784 causeOf IL-10,mediated
R8534 T16746 T16782 themeOf STAT3,phosphorylation
R8535 T16748 T16785 themeOf IL-10R,interaction
R8536 T16749 T16785 themeOf IL-10,interaction
R8537 T16750 T16786 themeOf STAT1,activation
R8538 T16751 T16786 themeOf STAT3,activation
R8539 T16752 T16789 themeOf IL-10,mediated
R8540 T16753 T16790 themeOf STAT3,overexpression
R8541 T16754 T16788 themeOf STAT3,deficient
R8542 T16756 T16792 themeOf STAT1,induction
R8543 T16756 T16793 themeOf STAT1,phosphorylation
R8544 T16757 T16792 themeOf STAT3,induction
R8545 T16757 T16793 themeOf STAT3,phosphorylation
R8546 T16758 T16792 themeOf IL-10,induction
R8547 T16760 T16794 themeOf STAT3,phosphorylation
R8548 T16761 T16795 themeOf IL-10,activation
R8549 T16763 T16797 themeOf STAT3,phosphorylated
R8550 T16765 T16798 themeOf STAT3,phosphorylation
R8551 T16766 T16799 themeOf STAT3,phosphorylation
R8552 T16767 T16801 themeOf IL-10,activated
R8553 T16768 T16802 themeOf STAT3,phosphorylation
R8554 T16769 T16806 causeOf IL-10,induced
R8555 T16770 T16803 themeOf STAT3,phosphorylation
R8556 T16772 T16808 causeOf IL-10,induced
R8557 T16773 T16807 themeOf STAT1,phosphorylation
R8558 T16779 T16814 causeOf IL-10,induced
R8559 T16780 T16810 themeOf STAT3,activation
R8560 T16781 T16812 themeOf STAT3,association
R8561 T16781 T16813 themeOf STAT3,phosphorylation
R8562 T16782 T16783 themeOf phosphorylation,Defective
R8563 T16782 T16784 themeOf phosphorylation,mediated
R8564 T16785 T16787 causeOf interaction,induces
R8565 T16785 T16787 causeOf interaction,induces
R8566 T16786 T16787 themeOf activation,induces
R8567 T16786 T16787 themeOf activation,induces
R8568 T16790 T16791 themeOf overexpression,dominant-negative
R8569 T16791 T16790 themeOf dominant-negative,overexpression
R8570 T16793 T16792 themeOf phosphorylation,induction
R8571 T16793 T16792 themeOf phosphorylation,induction
R8572 T16794 T16796 themeOf phosphorylation,induced
R8573 T16795 T16796 causeOf activation,induced
R8574 T16799 T16800 themeOf phosphorylation,augmented
R8575 T16802 T16804 themeOf phosphorylation,sustained
R8576 T16803 T16805 themeOf phosphorylation,defective
R8577 T16803 T16806 themeOf phosphorylation,induced
R8578 T16807 T16808 themeOf phosphorylation,induced
R8579 T16808 T16809 themeOf induced,detected
R8580 T16810 T16811 themeOf activation,diminished
R8581 T16810 T16814 themeOf activation,induced
R8582 T16812 T16811 themeOf association,diminished
R8583 T16813 T16815 themeOf phosphorylation,sustained
R9881 T19445 T19501 causeOf IL-6,mediated
R9882 T19446 T19499 themeOf STAT3,phosphorylation
R9883 T19447 T19500 themeOf IL-10,effect
R9884 T19451 T19502 themeOf IL-10,activated
R9885 T19452 T19504 causeOf IL-6,induces
R9886 T19453 T19503 themeOf STAT3,activation
R9887 T19454 T19502 themeOf STAT3,activated
R9888 T19459 T19505 themeOf IL-6,detected
R9889 T19462 T19506 themeOf STAT3,activation
R9890 T19463 T19507 themeOf IL-10,inhibition
R9891 T19464 T19511 themeOf STAT1,phosphorylation
R9892 T19464 T19512 themeOf STAT1,activated
R9893 T19465 T19511 themeOf STAT3,phosphorylation
R9894 T19465 T19512 themeOf STAT3,activated
R9895 T19466 T19512 causeOf IL-6,activated
R9896 T19466 T19512 causeOf IL-6,activated
R9897 T19466 T19512 causeOf IL-6,activated
R9898 T19466 T19512 causeOf IL-6,activated
R9899 T19470 T19513 themeOf STAT3,phosphorylation
R9900 T19471 T19513 themeOf STAT1,phosphorylation
R9901 T19472 T19514 themeOf STAT3,activation
R9902 T19474 T19517 causeOf IL-6,activating
R9903 T19475 T19517 themeOf STAT3,activating
R9904 T19476 T19518 themeOf STAT1,activation
R9905 T19478 T19519 themeOf STAT1,activation
R9906 T19479 T19520 themeOf STAT3,activation
R9907 T19480 T19521 themeOf STAT1,inhibitors
R9908 T19482 T19526 causeOf IL-10,effect
R9909 T19483 T19524 themeOf IFN-γ,production
R9910 T19489 T19527 themeOf IFN-γ,production
R9911 T19491 T19534 causeOf IL-10,mediated
R9912 T19492 T19529 themeOf IFN-γ,production
R9913 T19494 T19530 themeOf IL-10,responsiveness
R9914 T19496 T19535 themeOf STAT3,activation
R9915 T19499 T19501 themeOf phosphorylation,mediated
R9916 T19503 T19504 themeOf activation,induces
R9917 T19506 T19508 themeOf activation,responsible
R9918 T19506 T19509 themeOf activation,sustained
R9919 T19507 T19510 themeOf inhibition,resistance
R9920 T19511 T19512 themeOf phosphorylation,activated
R9921 T19511 T19512 themeOf phosphorylation,activated
R9922 T19513 T19516 themeOf phosphorylation,induce
R9923 T19513 T19516 themeOf phosphorylation,induce
R9924 T19514 T19515 themeOf activation,abolished
R9925 T19518 T19522 themeOf activation,lack
R9926 T19519 T19523 themeOf activation,required
R9927 T19524 T19525 themeOf production,inhibit
R9928 T19525 T19526 themeOf inhibit,effect
R9929 T19527 T19528 themeOf production,stimulated
R9930 T19529 T19531 themeOf production,inhibition
R9931 T19530 T19532 themeOf responsiveness,modulate
R9932 T19531 T19533 themeOf inhibition,reduced
R9933 T19531 T19534 themeOf inhibition,mediated
R9934 T19534 T19531 themeOf mediated,inhibition
R9935 T19535 T19536 themeOf activation,induction
R9936 T19536 T19537 themeOf induction,role
R10734 T21209 T21243 themeOf SOCS1,expression
R10735 T21211 T21246 causeOf IL-6,induces
R10737 T21212 T21245 themeOf SOCS1,inhibitors
R10739 T21214 T21249 themeOf IL-6,regulating
R10741 T21216 T21250 causeOf SOCS3,inhibit
R10742 T21217 T21247 themeOf STAT3,activation
R10743 T21218 T21248 causeOf IL-6,induced
R10745 T21220 T21253 causeOf SOCS1,inhibit
R10746 T21221 T21254 causeOf IL-10,mediated
R10747 T21222 T21251 themeOf STAT3,activation
R10748 T21223 T21255 causeOf IFN-γ,mediated
R10749 T21224 T21252 themeOf STAT1,activation
R10750 T21228 T21256 themeOf SOCS1,expression
R10752 T21232 T21257 themeOf SOCS1,higher
R10753 T21233 T21258 themeOf SOCS3,transcripts
R10754 T21235 T21259 themeOf SOCS1,expression
R10755 T21240 T21261 themeOf STAT3,activation
R10756 T21241 T21262 themeOf SOCS1,abundance
R10757 T21243 T21244 themeOf expression,High
R10758 T21245 T21246 themeOf inhibitors,induces
R10760 T21247 T21248 themeOf activation,induced
R10761 T21247 T21250 themeOf activation,inhibit
R10765 T21251 T21254 themeOf activation,mediated
R10766 T21252 T21253 themeOf activation,inhibit
R10767 T21252 T21255 themeOf activation,mediated
R10768 T21259 T21260 themeOf expression,Constitutive
R10770 T21262 T21263 themeOf abundance,due
R10738 T21213 T21245 themeOf SOCS3,inhibitors
R10759 T21245 T21246 themeOf inhibitors,induces
R10769 T21261 T21263 causeOf activation,due
R10736 T21211 T21246 causeOf IL-6,induces
R10740 T21215 T21249 themeOf IL-10,regulating
R10744 T21219 T21248 causeOf IL-10,induced
R10751 T21229 T21256 themeOf SOCS3,expression
R10762 T21247 T21248 themeOf activation,induced
R10763 T21248 T21247 themeOf induced,activation
R10764 T21248 T21247 themeOf induced,activation

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue Negation Speculation
T21364 7193-7198 Protein denotes SOCS3
T21363 8022-8027 Protein denotes SOCS1
T21362 7106-7119 Protein denotes of SOCS1 mRNA
T21361 7532-7537 Protein denotes IL-10
T19801 5419-5448 Negative_regulation denotes IL-10 inhibition in active RA
T19800 4658-4679 Phosphorylation denotes STAT3 phosphorylation
T19799 6412-6443 Negative_regulation denotes inhibit IFN-γ production by CD4
T19798 6255-6276 Positive_regulation denotes with STAT3 activation
T19797 5772-5830 Phosphorylation denotes STAT phosphorylation was examined by western blot analysis
T19796 5078-5136 Positive_regulation denotes constitutive activation of STAT3 in mononuclear cells [31]
T19795 5860-5907 Phosphorylation denotes tyrosine phosphorylation of STAT3 but not STAT1
T19794 4734-4752 Positive_regulation denotes STAT3 is activated
T19793 6300-6315 Positive_regulation denotes STAT1 signaling
T19792 6996-7015 Positive_regulation denotes of STAT3 activation
T19791 6369-6443 Negative_regulation denotes IL-6 could suppress the effect of IL-10 to inhibit IFN-γ production by CD4 true
T19790 6761-6777 Gene_expression denotes IFN-γ production
T19789 5913-5934 Positive_regulation denotes this STAT3 activation
T19788 4684-4724 Negative_regulation denotes inhibition of IL-10 effect in normal CD4
T19787 6125-6144 Positive_regulation denotes of STAT1 activation
T19786 6420-6443 Gene_expression denotes IFN-γ production by CD4
T19785 6565-6583 Positive_regulation denotes CD28 costimulation
T17018 3329-3381 Positive_regulation denotes activation of the latent transcription factors STAT1
T17017 3601-3647 Positive_regulation denotes of dominant-negative STAT3 overexpression [30]
T17016 3601-3647 Gene_expression denotes of dominant-negative STAT3 overexpression [30]
T17015 4527-4557 Positive_regulation denotes IL-10-induced STAT3 activation
T17014 4028-4054 Phosphorylation denotes this STAT3 phosphorylation
T17013 3870-3893 Positive_regulation denotes IL-10 activation for 20
T17012 4475-4521 Positive_regulation denotes the major IL-10-activated STAT in CD4+ T cells
T17011 4605-4641 Phosphorylation denotes with sustained STAT3 phosphorylation
T17010 3189-3254 Regulation denotes Defective IL-10-mediated STAT3 phosphorylation in RA CD4+ T cells
T17009 4306-4426 Phosphorylation denotes On the other hand, IL-10-induced STAT1 phosphorylation was not detected in either RA CD4+ T cells or normal CD4+ T cells
T17008 3935-4006 Phosphorylation denotes In contrast, STAT3 was phosphorylated in freshly isolated PB CD4+ cells
T17007 3214-3254 Phosphorylation denotes STAT3 phosphorylation in RA CD4+ T cells
T17006 3255-3291 Binding denotes The interaction of IL-10R with IL-10
T17005 3676-3697 Phosphorylation denotes STAT3 phosphorylation
T17004 4089-4110 Phosphorylation denotes STAT3 phosphorylation
T17003 4216-4261 Phosphorylation denotes defective IL-10-induced STAT3 phosphorylation
T17002 3813-3834 Phosphorylation denotes STAT3 phosphorylation
T17001 3922-3925 Protein denotes Fig
T17000 3993-3995 Protein denotes PB
T16999 3300-3308 Entity denotes tyrosine
T15255 2785-2811 Entity denotes IL-10R1 on PB CD4+ T cells
T15254 3177-3186 Protein denotes active RA
T14350 611-627 Gene_expression denotes IFN-γ production
T14349 1422-1457 Regulation denotes effect of IL-10 on IFN-γ production
T14348 671-720 Gene_expression denotes IFN-γ production by activated normal CD4+ T cells
T14347 2007-2093 Regulation denotes IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease, true
T14346 1336-1391 Gene_expression denotes IFN-γ production without IL-10 among these three groups
T14345 2007-2022 Gene_expression denotes IL-2 production
T14344 1834-1923 Gene_expression denotes In addition, we compared IL-2 production by CD4+ T cells after CD3 and CD28 costimulation
T14343 1905-1923 Positive_regulation denotes CD28 costimulation
T14342 898-959 Binding denotes the maximal but not complete inhibition by IL-10 was obtained
T14341 1008-1040 Gene_expression denotes IFN-γ production by CD4+ T cells
T14340 23-78 Negative_regulation denotes IL-10 inhibition of IFN-γ production in RA CD4+ T cells
T14339 1055-1073 Positive_regulation denotes CD28 costimulation
T14338 1438-1457 Gene_expression denotes on IFN-γ production
T14337 1422-1506 Negative_regulation denotes effect of IL-10 on IFN-γ production was significantly limited in the active RA group
T14294 390-405 Entity denotes PB CD4+ T cells
T14293 1393-1396 Protein denotes Fig
T14292 2305-2313 Protein denotes of IL-10
T14291 509-521 Protein denotes CD3 antibody
T14290 374-380 Protein denotes IL-10,
T14289 1959-1961 Protein denotes RA
T14288 1537-1539 Protein denotes RA
T14287 1692-1728 Entity denotes CD4+ T cells from active RA patients
T14286 1008-1013 Protein denotes IFN-γ
T14285 1025-1040 Entity denotes by CD4+ T cells
T14284 2234-2249 Entity denotes RA CD4+ T cells
T14283 1047-1050 Protein denotes CD3
T14282 2234-2236 Protein denotes RA
T14281 1755-1760 Protein denotes IFN-γ
T14280 1905-1909 Protein denotes CD28
T14279 352-370 Entity denotes of RA CD4+ T cells
T14278 1664-1667 Protein denotes Fig
T14277 509-512 Protein denotes CD3
T14276 663-666 Protein denotes Fig
T14275 1897-1900 Protein denotes CD3
T14274 390-392 Protein denotes PB
T14273 1613-1624 Protein denotes inactive RA
T14272 1589-1598 Protein denotes active RA
T14271 125-151 Entity denotes effective antigen-specific
T14270 240-244 Protein denotes CD28
T14269 1441-1446 Protein denotes IFN-γ
T14336 40-59 Gene_expression denotes of IFN-γ production
T14335 23-28 Protein denotes IL-10
T14334 794-796 Protein denotes RA
T14333 794-809 Entity denotes RA CD4+ T cells
T14332 1717-1719 Protein denotes RA
T14331 2040-2056 Protein denotes by 1 ng/ml IL-10
T14330 1803-1822 Entity denotes normal CD4+ T cells
T14329 1093-1121 Protein denotes 1 ng/ml IL-10 in RA patients
T14328 1498-1500 Protein denotes RA
T14327 63-78 Entity denotes RA CD4+ T cells
T14326 43-48 Protein denotes IFN-γ
T14325 1361-1366 Protein denotes IL-10
T14324 671-676 Protein denotes IFN-γ
T14323 1230-1233 Protein denotes CRP
T14322 536-544 Protein denotes antibody
T14321 63-65 Protein denotes RA
T14320 1336-1341 Protein denotes IFN-γ
T14319 285-314 Protein denotes phosphatidylinositol 3-kinase
T14318 184-189 Protein denotes IL-10
T14317 2060-2062 Protein denotes RA
T14316 584-606 Protein denotes of IL-10 for 36 hours,
T14315 79-109 Protein denotes The CD28 costimulatory pathway
T14314 688-720 Entity denotes by activated normal CD4+ T cells
T14313 431-440 Protein denotes active RA
T14312 725-783 Protein denotes mostly inhibited at concentrations as low as 1 ng/ml IL-10
T14311 2165-2182 Entity denotes 61.1 ± 13.7%; P <
T14310 1875-1923 Entity denotes by CD4+ T cells after CD3 and CD28 costimulation
T14309 1110-1112 Protein denotes RA
T14308 1780-1793 Protein denotes 1 ng/ml IL-10
T14307 2007-2011 Protein denotes IL-2
T14306 938-946 Protein denotes by IL-10
T14305 851-859 Protein denotes of IFN-γ
T14304 611-616 Protein denotes IFN-γ
T14303 1859-1863 Protein denotes IL-2
T14302 526-535 Protein denotes anti-CD28
T14301 355-357 Protein denotes RA
T14300 1943-1994 Protein denotes IL-10 in active RA patients and in healthy controls
T14299 1173-1176 Protein denotes CRP
T14298 879-892 Protein denotes 1 ng/ml IL-10
T14297 1055-1059 Protein denotes CD28
T14296 1429-1437 Protein denotes of IL-10
T14295 240-269 Entity denotes CD28 tyrosine phosphorylation
T16958 4509-4521 Entity denotes CD4+ T cells
T16957 4033-4038 Protein denotes STAT3
T16956 4579-4589 Protein denotes active RA,
T16955 4115-4173 Protein denotes augmented only when activated by as much as 10 ng/ml IL-10
T16954 4276-4294 Entity denotes RA ST CD4+ T cells
T16953 4276-4294 Protein denotes RA ST CD4+ T cells
T16952 3698-3716 Protein denotes by IL-10 in PB CD4
T16951 3572-3589 Entity denotes human macrophages
T16950 3386-3395 Protein denotes STAT3 [3]
T16949 3189-3204 Protein denotes Defective IL-10
T16948 3340-3381 Protein denotes of the latent transcription factors STAT1
T16947 4475-4521 Protein denotes the major IL-10-activated STAT in CD4+ T cells
T16946 4388-4390 Protein denotes RA
T15288 2725-2753 Negative_regulation denotes limited receptor expression,
T15287 2725-2753 Gene_expression denotes limited receptor expression,
T15286 2563-2581 Gene_expression denotes IL-10R1 expression
T15285 2678-2694 Negative_regulation denotes IL-10 inhibition
T15284 2944-2965 Gene_expression denotes of IL-10R1 expression
T15283 2361-2403 Localization denotes of cell surface IL-10R1 on RA CD4+ T cells
T15282 2785-2792 Protein denotes IL-10R1
T15281 2969-2981 Entity denotes CD4+ T cells
T15280 3136-3141 Protein denotes IL-10
T15279 2698-2700 Protein denotes RA
T15278 2404-2444 Entity denotes The functional receptor complex of IL-10
T15277 2471-2513 Protein denotes the primary ligand-binding component IL-10
T15276 2563-2570 Protein denotes IL-10R1
T15275 2549-2561 Protein denotes 2 IL-10R [1]
T15274 2733-2741 Protein denotes receptor
T15273 2471-2513 Entity denotes the primary ligand-binding component IL-10
T15272 2678-2683 Protein denotes IL-10
T15271 2629-2639 Protein denotes IL-10 [29]
T15270 2918-2921 Protein denotes Fig
T15269 2513-2515 Protein denotes R1
T15268 2947-2954 Protein denotes IL-10R1
T15267 2824-2826 Protein denotes RA
T15266 2754-2770 Entity denotes the cell surface
T15265 2796-2798 Protein denotes PB
T15264 2436-2444 Protein denotes of IL-10
T15263 2388-2390 Protein denotes RA
T15262 2404-2444 Protein denotes The functional receptor complex of IL-10
T15261 2698-2713 Entity denotes RA CD4+ T cells
T15260 3161-3186 Entity denotes CD4+ T cells of active RA
T15259 2364-2376 Entity denotes cell surface
T15258 3013-3015 Protein denotes RA
T15257 2361-2403 Protein denotes of cell surface IL-10R1 on RA CD4+ T cells
T15256 2361-2403 Entity denotes of cell surface IL-10R1 on RA CD4+ T cells
T16998 3976-4006 Entity denotes freshly isolated PB CD4+ cells
T16997 3487-3501 Protein denotes IL-10-mediated
T16996 4339-4344 Protein denotes STAT1
T16995 4216-4239 Protein denotes defective IL-10-induced
T16994 3718-3749 Entity denotes T cells from active RA patients
T16993 3710-3712 Protein denotes PB
T16992 4466-4471 Protein denotes STAT3
T16991 4089-4094 Protein denotes STAT3
T16990 4190-4195 Protein denotes STAT3
T16989 4541-4546 Protein denotes STAT3
T16988 4620-4625 Protein denotes STAT3
T16987 3870-3875 Protein denotes IL-10
T16986 3397-3437 Protein denotes Macrophage-specific STAT3-deficient mice
T16985 3813-3818 Protein denotes STAT3
T16984 3397-3416 Entity denotes Macrophage-specific
T16983 3340-3381 Protein denotes of the latent transcription factors STAT1
T16982 3676-3681 Protein denotes STAT3
T16981 3281-3291 Protein denotes with IL-10
T16980 3601-3647 Protein denotes of dominant-negative STAT3 overexpression [30]
T16979 4428-4431 Protein denotes Fig
T16978 4479-4500 Protein denotes major IL-10-activated
T16977 3666-3671 Protein denotes STAT1
T16976 3239-3254 Entity denotes RA CD4+ T cells
T16975 4276-4278 Protein denotes RA
T16974 4388-4403 Entity denotes RA CD4+ T cells
T16973 3738-3740 Protein denotes RA
T16972 4325-4338 Protein denotes IL-10-induced
T16971 3948-3953 Protein denotes STAT3
T16970 3710-3716 Protein denotes PB CD4
T16969 3239-3241 Protein denotes RA
T16968 3214-3219 Protein denotes STAT3
T16967 3901-3920 Entity denotes normal CD4+ T cells
T16966 4527-4540 Protein denotes IL-10-induced
T16965 4240-4245 Protein denotes STAT3
T16964 4012-4014 Protein denotes RA
T16963 3613-3627 Protein denotes negative STAT3
T16962 4296-4299 Protein denotes Fig
T16961 4407-4426 Entity denotes normal CD4+ T cells
T16960 3271-3280 Protein denotes of IL-10R
T16959 3456-3461 Protein denotes STAT3
T19745 5607-5614 Entity denotes T cells
T19744 5114-5136 Entity denotes mononuclear cells [31]
T19743 4714-4724 Protein denotes normal CD4
T19742 5902-5907 Protein denotes STAT1
T19741 5384-5389 Protein denotes STAT3
T19740 6260-6265 Protein denotes STAT3
T19739 6779-6782 Protein denotes Fig
T19738 5977-5981 Protein denotes IL-6
T19737 6128-6133 Protein denotes STAT1
T19736 4726-4733 Entity denotes T cells
T19735 6690-6694 Protein denotes IL-6
T19734 6711-6723 Entity denotes normal cells
T19733 4644-4648 Protein denotes IL-6
T19732 5992-5995 Protein denotes Fig
T19731 5184-5186 Protein denotes RA
T19730 5465-5470 Protein denotes STAT3
T19729 5728-5766 Entity denotes anti-IL-6 antibody or control antibody
T19728 6761-6766 Protein denotes IFN-γ
T19727 4658-4663 Protein denotes STAT3
T19726 5315-5322 Protein denotes of IL-6
T19725 6732-6746 Protein denotes IL-10-mediated
T19724 6650-6655 Protein denotes IFN-γ
T19723 6999-7004 Protein denotes STAT3
T19722 6490-6517 Protein denotes 10 ng/ml IL-6 for 36 hours,
T19721 4924-4947 Protein denotes epidermal growth factor
T19720 6300-6305 Protein denotes STAT1
T19719 7060-7068 Protein denotes of IL-10
T19718 4698-4703 Protein denotes IL-10
T19717 5419-5424 Protein denotes IL-10
T19716 4828-4832 Protein denotes IL-6
T19715 6226-6231 Protein denotes STAT1
T19714 6557-6560 Protein denotes CD3
T19713 6281-6315 Entity denotes that inhibitors of STAT1 signaling
T19712 5885-5893 Protein denotes of STAT3
T19711 5512-5548 Entity denotes normal CD4+ T cells (data not shown)
T19710 5047-5049 Protein denotes RA
T19709 5144-5148 Protein denotes IL-6
T19708 6518-6537 Entity denotes normal CD4+ T cells
T19707 4873-4885 Protein denotes oncostatin M
T19706 4734-4739 Protein denotes STAT3
T19705 5501-5508 Protein denotes by IL-6
T19704 6437-6443 Protein denotes by CD4
T19703 5169-5196 Protein denotes sera of active RA patients,
T17019 4475-4521 Localization denotes the major IL-10-activated STAT in CD4+ T cells
T17020 4190-4211 Phosphorylation denotes STAT3 phosphorylation
T19784 6646-6666 Gene_expression denotes the IFN-γ production
T19783 6226-6242 Positive_regulation denotes STAT1 activation
T19782 6732-6757 Regulation denotes IL-10-mediated inhibition
T19781 6088-6114 Protein denotes sera of active RA patients
T19780 4964-4974 Protein denotes IL-10 [4],
T19779 5019-5023 Protein denotes IL-6
T19778 5595-5605 Protein denotes Normal CD4
T19777 5738-5746 Entity denotes antibody
T19776 4817-4886 Protein denotes cytokines (IL-6, IL-11, leukemia inhibitory factor, and oncostatin M)
T19775 6870-6878 Protein denotes to IL-10
T19774 6825-6832 Protein denotes of IL-6
T19773 6369-6373 Protein denotes IL-6
T19772 6611-6641 Protein denotes of 1 ng/ml IL-10 for 36 hours,
T19771 5772-5776 Protein denotes STAT
T19770 6953-6957 Protein denotes IL-6
T19769 6198-6205 Protein denotes of IL-6
T19768 4841-4867 Protein denotes leukemia inhibitory factor
T19767 6400-6408 Protein denotes of IL-10
T19766 5276-5291 Entity denotes of CD4+ T cells
T19765 6565-6569 Protein denotes CD28
T19764 5102-5110 Protein denotes of STAT3
T19763 6030-6034 Protein denotes IL-6
T19762 4888-4918 Protein denotes platelet-derived growth factor
T19761 6334-6336 Entity denotes RA
T19760 4834-4839 Protein denotes IL-11
T19759 7072-7087 Entity denotes RA CD4+ T cells
T19758 5699-5701 Protein denotes RA
T19757 6445-6452 Entity denotes T cells
T19756 5918-5923 Protein denotes STAT3
T19755 4802-4806 Protein denotes IL-6
T19754 5860-5868 Entity denotes tyrosine
T19753 6145-6150 Protein denotes by RA
T19752 5439-5448 Protein denotes active RA
T19751 6103-6105 Protein denotes RA
T19750 5455-5460 Protein denotes STAT1
T19749 7072-7074 Protein denotes RA
T19748 6848-6854 Entity denotes T-cell
T19747 5832-5834 Protein denotes RA
T19746 6420-6425 Protein denotes IFN-γ
T21408 8251-8254 Protein denotes Fig
T21407 7193-7207 Protein denotes SOCS3 proteins
T21406 8202-8249 Protein denotes normal CD4+ T cells stimulated by 10 ng/ml IL-6
T21405 7454-7461 Protein denotes by IL-6
T21404 7597-7611 Protein denotes IL-10-mediated
T21403 8301-8316 Protein denotes Defective IL-10
T21402 8325-8330 Protein denotes STAT3
T21401 7429-7434 Protein denotes STAT3
T21400 7612-7617 Protein denotes STAT3
T21399 8131-8144 Protein denotes of SOCS1 mRNA
T21398 7109-7114 Protein denotes SOCS1
T21397 8148-8163 Entity denotes RA CD4+ T cells
T21396 7336-7373 Protein denotes other cytokine-signaling pathways [7]
T21395 7774-7779 Protein denotes STAT3
T21394 7802-7809 Entity denotes T cells
T21366 7562-7567 Protein denotes SOCS1
T21365 7679-7684 Protein denotes STAT1
T21393 8214-8221 Entity denotes T cells
T21392 7791-7800 Protein denotes of RA CD4
T21391 7523-7527 Protein denotes IL-6
T21390 7860-7862 Protein denotes PB
T21389 8415-8430 Entity denotes RA CD4+ T cells
T21388 7152-7208 Entity denotes two potent inhibitors of JAKs (SOCS1 and SOCS3 proteins)
T21387 8048-8065 Protein denotes SOCS3 transcripts
T21386 7664-7678 Protein denotes IFN-γ-mediated
T21385 7123-7138 Entity denotes RA CD4+ T cells
T21384 8134-8139 Protein denotes SOCS1
T21383 8048-8053 Protein denotes SOCS3
T21382 7183-7188 Protein denotes SOCS1
T21381 8415-8417 Protein denotes RA
T21380 7473-7478 Protein denotes IL-10
T21379 7177-7208 Protein denotes JAKs (SOCS1 and SOCS3 proteins)
T21378 7825-7845 Protein denotes SOCS1 and SOCS3 mRNA
T21377 7975-7994 Entity denotes The RA CD4+ T cells
T21376 7139-7143 Protein denotes IL-6
T21375 7375-7380 Protein denotes SOCS3
T21374 7940-7973 Protein denotes by semiquantitative real-time PCR
T21373 8403-8411 Protein denotes of SOCS1
T21372 7860-7875 Entity denotes PB CD4+ T cells
T21371 8148-8150 Protein denotes RA
T21370 7835-7840 Protein denotes SOCS3
T21369 8083-8105 Entity denotes CD4+ T cells (Fig. 6a)
T21368 7888-7890 Protein denotes RA
T21367 7979-7981 Protein denotes RA
T21424 7597-7628 Regulation denotes IL-10-mediated STAT3 activation
T21423 7597-7628 Positive_regulation denotes IL-10-mediated STAT3 activation
T21422 7743-7800 Positive_regulation denotes in the defective IL-10-induced STAT3 activation of RA CD4
T21421 7825-7925 Gene_expression denotes SOCS1 and SOCS3 mRNA expression in PB CD4+ T cells from active RA patients and from healthy controls
T21420 7825-7925 Transcription denotes SOCS1 and SOCS3 mRNA expression in PB CD4+ T cells from active RA patients and from healthy controls
T21419 7429-7478 Positive_regulation denotes STAT3 activation induced by IL-6 but not by IL-10
T21418 8202-8250 Localization denotes normal CD4+ T cells stimulated by 10 ng/ml IL-6
T21417 7090-7138 Gene_expression denotes High expression of SOCS1 mRNA in RA CD4+ T cells
T21416 7664-7700 Positive_regulation denotes IFN-γ-mediated STAT1 activation [32]
T21415 7664-7700 Regulation denotes IFN-γ-mediated STAT1 activation [32]
T21414 8120-8163 Gene_expression denotes expression of SOCS1 mRNA in RA CD4+ T cells
T21413 8325-8341 Positive_regulation denotes STAT3 activation
T21412 7825-7830 Protein denotes SOCS1
T21411 7750-7773 Protein denotes defective IL-10-induced
T21410 7123-7125 Protein denotes RA
T21409 7794-7796 Protein denotes RA
R7392 T14269 T14338 themeOf IFN-γ,on IFN-γ production
R7393 T14280 T14343 themeOf CD28,CD28 costimulation
R7394 T14286 T14341 themeOf IFN-γ,IFN-γ production by CD4+ T cells
R7395 T14296 T14349 causeOf of IL-10,effect of IL-10 on IFN-γ production
R7396 T14297 T14339 themeOf CD28,CD28 costimulation
R7397 T14303 T14344 themeOf IL-2,"In addition, we compared IL-2 production by CD4+ T cells after CD3 and CD28 costimulation"
R7398 T14304 T14350 themeOf IFN-γ,IFN-γ production
R7399 T14307 T14345 themeOf IL-2,IL-2 production
R7400 T14320 T14346 themeOf IFN-γ,IFN-γ production without IL-10 among these three groups
R7401 T14324 T14348 themeOf IFN-γ,IFN-γ production by activated normal CD4+ T cells
R7402 T14326 T14336 themeOf IFN-γ,of IFN-γ production
R7403 T14331 T14347 causeOf by 1 ng/ml IL-10,"IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease,"
R7404 T14335 T14340 causeOf IL-10,IL-10 inhibition of IFN-γ production in RA CD4+ T cells
R7405 T14336 T14340 themeOf of IFN-γ production,IL-10 inhibition of IFN-γ production in RA CD4+ T cells
R7406 T14338 T14349 themeOf on IFN-γ production,effect of IL-10 on IFN-γ production
R7407 T14345 T14347 themeOf IL-2 production,"IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease,"
R7408 T14349 T14337 themeOf effect of IL-10 on IFN-γ production,effect of IL-10 on IFN-γ production was significantly limited in the active RA group
R7786 T15257 T15283 themeOf of cell surface IL-10R1 on RA CD4+ T cells,of cell surface IL-10R1 on RA CD4+ T cells
R7787 T15259 T15283 locationOf cell surface,of cell surface IL-10R1 on RA CD4+ T cells
R7788 T15268 T15284 themeOf IL-10R1,of IL-10R1 expression
R7789 T15272 T15285 themeOf IL-10,IL-10 inhibition
R7790 T15274 T15287 themeOf receptor,"limited receptor expression,"
R7791 T15276 T15286 themeOf IL-10R1,IL-10R1 expression
R7792 T15287 T15288 themeOf "limited receptor expression,","limited receptor expression,"
R8651 T16947 T17019 themeOf the major IL-10-activated STAT in CD4+ T cells,the major IL-10-activated STAT in CD4+ T cells
R8652 T16947 T17012 themeOf the major IL-10-activated STAT in CD4+ T cells,the major IL-10-activated STAT in CD4+ T cells
R8653 T16948 T17018 themeOf of the latent transcription factors STAT1,activation of the latent transcription factors STAT1
R8654 T16949 T17010 causeOf Defective IL-10,Defective IL-10-mediated STAT3 phosphorylation in RA CD4+ T cells
R8655 T16957 T17014 themeOf STAT3,this STAT3 phosphorylation
R8656 T16958 T17019 locationOf CD4+ T cells,the major IL-10-activated STAT in CD4+ T cells
R8657 T16960 T17006 themeOf of IL-10R,The interaction of IL-10R with IL-10
R8658 T16963 T17017 themeOf negative STAT3,of dominant-negative STAT3 overexpression [30]
R8659 T16963 T17016 themeOf negative STAT3,of dominant-negative STAT3 overexpression [30]
R8660 T16965 T17003 themeOf STAT3,defective IL-10-induced STAT3 phosphorylation
R8661 T16968 T17007 themeOf STAT3,STAT3 phosphorylation in RA CD4+ T cells
R8662 T16971 T17008 themeOf STAT3,"In contrast, STAT3 was phosphorylated in freshly isolated PB CD4+ cells"
R8663 T16978 T17012 causeOf major IL-10-activated,the major IL-10-activated STAT in CD4+ T cells
R8664 T16981 T17006 themeOf with IL-10,The interaction of IL-10R with IL-10
R8665 T16982 T17005 themeOf STAT3,STAT3 phosphorylation
R8666 T16985 T17002 themeOf STAT3,STAT3 phosphorylation
R8667 T16987 T17013 themeOf IL-10,IL-10 activation for 20
R8668 T16988 T17011 themeOf STAT3,with sustained STAT3 phosphorylation
R8669 T16989 T17015 themeOf STAT3,IL-10-induced STAT3 activation
R8670 T16990 T17020 themeOf STAT3,STAT3 phosphorylation
R8671 T16991 T17004 themeOf STAT3,STAT3 phosphorylation
R8672 T16996 T17009 themeOf STAT1,"On the other hand, IL-10-induced STAT1 phosphorylation was not detected in either RA CD4+ T cells or normal CD4+ T cells"
R8673 T17007 T17010 themeOf STAT3 phosphorylation in RA CD4+ T cells,Defective IL-10-mediated STAT3 phosphorylation in RA CD4+ T cells
R10018 T19706 T19794 themeOf STAT3,STAT3 is activated
R10019 T19712 T19795 themeOf of STAT3,tyrosine phosphorylation of STAT3 but not STAT1
R10020 T19715 T19783 themeOf STAT1,STAT1 activation
R10021 T19717 T19801 themeOf IL-10,IL-10 inhibition in active RA
R10022 T19720 T19793 causeOf STAT1,STAT1 signaling
R10023 T19723 T19792 themeOf STAT3,of STAT3 activation
R10024 T19724 T19784 themeOf IFN-γ,the IFN-γ production
R10025 T19725 T19782 causeOf IL-10-mediated,IL-10-mediated inhibition
R10026 T19727 T19800 themeOf STAT3,STAT3 phosphorylation
R10027 T19728 T19790 themeOf IFN-γ,IFN-γ production
R10028 T19737 T19787 themeOf STAT1,of STAT1 activation
R10029 T19740 T19798 themeOf STAT3,with STAT3 activation
R10030 T19746 T19786 themeOf IFN-γ,IFN-γ production by CD4
R10031 T19754 T19712 partOf tyrosine,of STAT3
R10032 T19754 T19795 siteOf tyrosine,tyrosine phosphorylation of STAT3 but not STAT1
R10033 T19756 T19789 themeOf STAT3,this STAT3 activation
R10034 T19764 T19796 themeOf of STAT3,constitutive activation of STAT3 in mononuclear cells [31]
R10035 T19765 T19785 themeOf CD28,CD28 costimulation
R10036 T19771 T19797 themeOf STAT,STAT phosphorylation was examined by western blot analysis
R10037 T19773 T19791 causeOf IL-6,IL-6 could suppress the effect of IL-10 to inhibit IFN-γ production by CD4
R10038 T19786 T19799 themeOf IFN-γ production by CD4,inhibit IFN-γ production by CD4
R10803 T21362 T21417 themeOf of SOCS1 mRNA,High expression of SOCS1 mRNA in RA CD4+ T cells
R10804 T21365 T21416 themeOf STAT1,IFN-γ-mediated STAT1 activation [32]
R10805 T21378 T21420 themeOf SOCS1 and SOCS3 mRNA,SOCS1 and SOCS3 mRNA expression in PB CD4+ T cells from active RA patients and from healthy controls
R10806 T21378 T21421 themeOf SOCS1 and SOCS3 mRNA,SOCS1 and SOCS3 mRNA expression in PB CD4+ T cells from active RA patients and from healthy controls
R10807 T21386 T21415 causeOf IFN-γ-mediated,IFN-γ-mediated STAT1 activation [32]
R10808 T21392 T21422 themeOf of RA CD4,in the defective IL-10-induced STAT3 activation of RA CD4
R10809 T21393 T21418 locationOf T cells,normal CD4+ T cells stimulated by 10 ng/ml IL-6
R10810 T21395 T21422 causeOf STAT3,in the defective IL-10-induced STAT3 activation of RA CD4
R10811 T21399 T21414 themeOf of SOCS1 mRNA,expression of SOCS1 mRNA in RA CD4+ T cells
R10812 T21400 T21423 themeOf STAT3,IL-10-mediated STAT3 activation
R10813 T21401 T21419 themeOf STAT3,STAT3 activation induced by IL-6 but not by IL-10
R10814 T21402 T21413 themeOf STAT3,STAT3 activation
R10815 T21404 T21424 causeOf IL-10-mediated,IL-10-mediated STAT3 activation
R10816 T21406 T21418 themeOf normal CD4+ T cells stimulated by 10 ng/ml IL-6,normal CD4+ T cells stimulated by 10 ng/ml IL-6
R10817 T21416 T21415 themeOf IFN-γ-mediated STAT1 activation [32],IFN-γ-mediated STAT1 activation [32]
R10818 T21423 T21424 themeOf IL-10-mediated STAT3 activation,IL-10-mediated STAT3 activation

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T15172 3066-3073 NNS denotes results
T21176 8256-8258 CD denotes 6b
T21175 8251-8255 NNP denotes Fig.
T21174 8250-8251 -LRB- denotes (
T21173 8245-8249 NN denotes IL-6
T21172 8239-8244 NN denotes ng/ml
T21171 8236-8238 CD denotes 10
T21170 8233-8235 IN denotes by
T21169 8222-8232 VBN denotes stimulated
T21168 8216-8221 NNS denotes cells
T21167 8214-8215 NNP denotes T
T21166 8212-8213 CD denotes +
T21165 8209-8212 NNP denotes CD4
T21164 8202-8208 JJ denotes normal
T21163 8199-8201 IN denotes in
T21162 8188-8198 NN denotes expression
T21161 8184-8187 DT denotes the
T21160 8179-8183 IN denotes with
T21159 8168-8178 JJ denotes comparable
T21158 8164-8167 VBD denotes was
T21157 8158-8163 NNS denotes cells
T21156 8156-8157 NNP denotes T
T21155 8154-8155 VBD denotes +
T21154 8151-8154 NNP denotes CD4
T21153 8148-8150 NNP denotes RA
T21152 8145-8147 IN denotes in
T21151 8140-8144 NNP denotes mRNA
T21150 8134-8139 CD denotes SOCS1
T21149 8131-8133 IN denotes of
T21148 8120-8130 NN denotes expression
T21147 8107-8119 JJ denotes Constitutive
T21146 8105-8106 . denotes .
T21145 8104-8105 -RRB- denotes )
T21144 8102-8104 CD denotes 6a
T21143 8097-8101 NNP denotes Fig.
T21142 8096-8097 -LRB- denotes (
T21141 8090-8095 NNS denotes cells
T21140 8088-8089 NNP denotes T
T21139 8086-8087 CD denotes +
T21138 8083-8086 NNP denotes CD4
T21137 8075-8082 VB denotes control
T21136 8071-8074 VBD denotes did
T21135 8066-8070 IN denotes than
T21134 8054-8065 NNS denotes transcripts
T21133 8048-8053 CD denotes SOCS3
T21132 8045-8047 IN denotes of
T21131 8038-8044 NNS denotes levels
T21130 8032-8037 JJR denotes lower
T21129 8028-8031 CC denotes but
T21128 8022-8027 CD denotes SOCS1
T21127 8019-8021 IN denotes of
T21126 8012-8018 NNS denotes levels
T21125 8005-8011 JJR denotes higher
T21124 7995-8004 VBD denotes contained
T21123 7989-7994 NNS denotes cells
T21122 7987-7988 NNP denotes T
T21121 7985-7986 VBD denotes +
T21120 7982-7985 NNP denotes CD4
T21119 7979-7981 NNP denotes RA
T21118 7975-7978 DT denotes The
T21117 7973-7974 . denotes .
T21116 7970-7973 NNP denotes PCR
T21115 7960-7969 JJ denotes real-time
T21114 7943-7959 JJ denotes semiquantitative
T21113 7940-7942 IN denotes by
T21112 7931-7939 VBN denotes compared
T21111 7926-7930 VBD denotes were
T21110 7917-7925 NNS denotes controls
T21109 7909-7916 JJ denotes healthy
T21108 7904-7908 IN denotes from
T21107 7900-7903 CC denotes and
T21106 7891-7899 NNS denotes patients
T21105 7888-7890 NNP denotes RA
T21104 7881-7887 JJ denotes active
T21103 7876-7880 IN denotes from
T21102 7870-7875 NNS denotes cells
T21101 7868-7869 NNP denotes T
T21100 7866-7867 VBD denotes +
T21099 7863-7866 NNP denotes CD4
T21098 7860-7862 NNP denotes PB
T21097 7857-7859 IN denotes in
T21096 7846-7856 NN denotes expression
T21095 7841-7845 NNP denotes mRNA
T21094 7835-7840 NNP denotes SOCS3
T21093 7831-7834 CC denotes and
T21092 7825-7830 NNP denotes SOCS1
T21091 7822-7824 IN denotes of
T21090 7815-7821 NNS denotes levels
T21089 7811-7814 DT denotes the
T21088 7809-7810 , denotes ,
T21087 7804-7809 NNS denotes cells
T21086 7802-7803 NNP denotes T
T21085 7800-7801 VBD denotes +
T21084 7797-7800 NNP denotes CD4
T21083 7794-7796 NNP denotes RA
T21082 7791-7793 IN denotes of
T21081 7780-7790 NN denotes activation
T21080 7774-7779 CD denotes STAT3
T21079 7760-7773 JJ denotes IL-10-induced
T21078 7750-7759 JJ denotes defective
T21077 7746-7749 DT denotes the
T21076 7743-7745 IN denotes in
T21075 7734-7742 VBN denotes involved
T21074 7729-7733 VBD denotes were
T21073 7723-7728 NNS denotes SOCSs
T21072 7715-7722 IN denotes whether
T21071 7705-7714 VB denotes determine
T21070 7702-7704 TO denotes To
T21069 7700-7701 . denotes .
T21068 7699-7700 NNP denotes ]
T21067 7697-7699 CD denotes 32
T21066 7696-7697 NNP denotes [
T21065 7685-7695 NN denotes activation
T21064 7679-7684 CD denotes STAT1
T21063 7664-7678 JJ denotes IFN-γ-mediated
T21062 7661-7663 IN denotes as
T21061 7656-7660 RB denotes well
T21060 7653-7655 RB denotes as
T21059 7651-7652 , denotes ,
T21058 7642-7651 NNS denotes responses
T21057 7633-7641 JJ denotes cellular
T21056 7629-7632 CC denotes and
T21055 7618-7628 NN denotes activation
T21054 7612-7617 CD denotes STAT3
T21053 7597-7611 JJ denotes IL-10-mediated
T21052 7589-7596 VB denotes inhibit
T21051 7579-7588 RB denotes partially
T21050 7576-7578 TO denotes to
T21049 7571-7575 JJ denotes able
T21048 7568-7570 VBZ denotes is
T21047 7562-7567 NNP denotes SOCS1
T21046 7560-7561 , denotes ,
T21045 7552-7560 NN denotes contrary
T21044 7548-7551 DT denotes the
T21043 7545-7547 IN denotes On
T21042 7543-7544 . denotes .
T21041 7542-7543 NNP denotes ]
T21040 7539-7542 CD denotes 8,9
T21039 7538-7539 NNP denotes [
T21038 7532-7537 NNP denotes IL-10
T21037 7528-7531 CC denotes and
T21036 7523-7527 NNP denotes IL-6
T21035 7520-7522 IN denotes of
T21034 7513-7519 NN denotes action
T21033 7503-7512 JJ denotes divergent
T21032 7499-7502 DT denotes the
T21031 7488-7498 VBG denotes regulating
T21030 7480-7487 RB denotes thereby
T21029 7478-7479 , denotes ,
T21028 7473-7478 NNP denotes IL-10
T21027 7470-7472 IN denotes by
T21026 7466-7469 RB denotes not
T21025 7462-7465 CC denotes but
T21024 7457-7461 NN denotes IL-6
T21023 7454-7456 IN denotes by
T21022 7446-7453 VBN denotes induced
T21021 7435-7445 NN denotes activation
T21020 7429-7434 JJ denotes STAT3
T21019 7421-7428 VB denotes inhibit
T21018 7408-7420 RB denotes specifically
T21017 7405-7407 TO denotes to
T21016 7399-7404 VBN denotes shown
T21015 7394-7398 VBN denotes been
T21014 7385-7393 RB denotes recently
T21013 7381-7384 VBZ denotes has
T21012 7375-7380 CD denotes SOCS3
T21011 7373-7374 . denotes .
T21010 7372-7373 NNP denotes ]
T21009 7371-7372 CD denotes 7
T21008 7370-7371 VBP denotes [
T21007 7361-7369 NNS denotes pathways
T21006 7342-7360 JJ denotes cytokine-signaling
T21005 7336-7341 JJ denotes other
T21004 7327-7335 VBG denotes opposing
T21003 7324-7326 IN denotes by
T21002 7313-7323 NN denotes inhibition
T21001 7303-7312 NN denotes crosstalk
T21000 7300-7302 IN denotes in
T20999 7295-7299 NN denotes role
T20998 7289-7294 JJ denotes major
T20997 7287-7288 DT denotes a
T20996 7282-7286 VB denotes play
T20995 7277-7281 RB denotes also
T20994 7273-7276 CC denotes but
T20993 7271-7272 , denotes ,
T20992 7261-7271 NN denotes inhibition
T20991 7252-7260 NN denotes feedback
T20990 7243-7251 JJ denotes negative
T20989 7240-7242 IN denotes of
T20988 7230-7239 NNS denotes mediators
T20987 7227-7229 IN denotes as
T20986 7223-7226 NN denotes act
T20985 7218-7222 JJ denotes only
T20984 7214-7217 RB denotes not
T20983 7209-7213 IN denotes that
T20982 7207-7208 -RRB- denotes )
T20981 7199-7207 NNS denotes proteins
T20980 7193-7198 CD denotes SOCS3
T20979 7189-7192 CC denotes and
T20978 7183-7188 CD denotes SOCS1
T20977 7182-7183 -LRB- denotes (
T20976 7177-7181 NNS denotes JAKs
T20975 7174-7176 IN denotes of
T20974 7163-7173 NNS denotes inhibitors
T20973 7156-7162 JJ denotes potent
T20972 7152-7155 CD denotes two
T20971 7144-7151 VBZ denotes induces
T20970 7139-7143 NNP denotes IL-6
T20969 7133-7138 NNS denotes cells
T20968 7131-7132 NNP denotes T
T20967 7129-7130 VBD denotes +
T20966 7126-7129 NNP denotes CD4
T20965 7123-7125 NNP denotes RA
T20964 7120-7122 IN denotes in
T20963 7115-7119 NNP denotes mRNA
T20962 7109-7114 CD denotes SOCS1
T20961 7106-7108 IN denotes of
T21208 8430-8431 . denotes .
T21207 8425-8430 NNS denotes cells
T21206 8423-8424 NNP denotes T
T21205 8421-8422 VBD denotes +
T21204 8418-8421 NNP denotes CD4
T21203 8415-8417 NNP denotes RA
T21202 8412-8414 IN denotes in
T21201 8406-8411 CD denotes SOCS1
T21200 8403-8405 IN denotes of
T21199 8393-8402 NN denotes abundance
T21198 8390-8392 DT denotes an
T21197 8387-8389 TO denotes to
T21196 8382-8386 NN denotes part
T21195 8379-8381 IN denotes in
T21194 8373-8378 JJS denotes least
T21193 8370-8372 IN denotes at
T21192 8366-8369 JJ denotes due
T21191 8363-8365 VB denotes be
T21190 8360-8362 TO denotes to
T21189 8352-8359 VBZ denotes appears
T21188 8342-8351 RB denotes therefore
T21187 8331-8341 NN denotes activation
T21186 8325-8330 CD denotes STAT3
T21185 8311-8324 JJ denotes IL-10-induced
T21184 8301-8310 JJ denotes Defective
T21183 8299-8300 . denotes .
T21182 8287-8299 NN denotes significance
T21181 8276-8286 JJ denotes functional
T21180 8272-8275 PRP$ denotes its
T21179 8261-8271 VBG denotes supporting
T21178 8259-8260 , denotes ,
T21177 8258-8259 -RRB- denotes )
T20960 7095-7105 NN denotes expression
T20959 7090-7094 NNP denotes High
T19444 7087-7088 . denotes .
T19443 7082-7087 NNS denotes cells
T19442 7080-7081 NNP denotes T
T19441 7078-7079 VBD denotes +
T19440 7075-7078 NNP denotes CD4
T19439 7072-7074 NNP denotes RA
T19438 7069-7071 IN denotes in
T19437 7063-7068 NN denotes IL-10
T19436 7060-7062 IN denotes of
T19435 7053-7059 NN denotes effect
T19434 7042-7052 JJ denotes inhibitory
T19433 7038-7041 DT denotes the
T19432 7035-7037 TO denotes to
T19431 7024-7034 NN denotes resistance
T19430 7020-7023 DT denotes the
T19429 7016-7019 CC denotes and
T19428 7005-7015 NN denotes activation
T19427 6999-7004 CD denotes STAT3
T19426 6996-6998 IN denotes of
T19425 6986-6995 NN denotes induction
T19424 6982-6985 DT denotes the
T19423 6977-6981 DT denotes both
T19422 6974-6976 IN denotes in
T19421 6969-6973 NN denotes role
T19420 6967-6968 DT denotes a
T19419 6962-6966 VB denotes have
T19418 6958-6961 MD denotes may
T19417 6953-6957 NNP denotes IL-6
T19416 6947-6952 VB denotes serum
T19415 6944-6946 TO denotes to
T19414 6935-6943 NN denotes exposure
T19413 6924-6934 JJ denotes persistent
T19412 6919-6923 IN denotes that
T19411 6911-6918 VBP denotes suggest
T19410 6902-6910 NNS denotes findings
T19409 6896-6901 DT denotes these
T19408 6894-6895 , denotes ,
T19407 6886-6894 RB denotes together
T19406 6880-6885 VBN denotes Taken
T19405 6878-6879 . denotes .
T19404 6873-6878 NNP denotes IL-10
T19403 6870-6872 TO denotes to
T19402 6855-6869 NN denotes responsiveness
T19401 6848-6854 NNP denotes T-cell
T19400 6839-6847 VB denotes modulate
T19399 6833-6838 MD denotes could
T19398 6828-6832 NN denotes IL-6
T19397 6825-6827 IN denotes of
T19396 6810-6824 NNS denotes concentrations
T19395 6805-6809 JJ denotes high
T19394 6800-6804 IN denotes that
T19393 6789-6799 VBG denotes indicating
T19392 6787-6788 , denotes ,
T19391 6786-6787 -RRB- denotes )
T19390 6784-6786 CD denotes 5b
T19389 6779-6783 NNP denotes Fig.
T19388 6778-6779 -LRB- denotes (
T19387 6767-6777 NN denotes production
T19386 6761-6766 JJ denotes IFN-γ
T19385 6758-6760 IN denotes of
T19384 6747-6757 NN denotes inhibition
T19383 6732-6746 JJ denotes IL-10-mediated
T19382 6724-6731 VBN denotes reduced
T19381 6718-6723 NNS denotes cells
T19380 6711-6717 JJ denotes normal
T19379 6708-6710 IN denotes of
T19378 6695-6707 NN denotes pretreatment
T19377 6690-6694 CD denotes IL-6
T19376 6688-6689 . denotes .
T19375 6683-6688 NNP denotes ELISA
T19374 6680-6682 IN denotes by
T19373 6671-6679 VBN denotes measured
T19372 6667-6670 VBD denotes was
T19371 6656-6666 NN denotes production
T19370 6650-6655 JJ denotes IFN-γ
T19369 6646-6649 DT denotes the
T19368 6642-6645 CC denotes and
T19367 6640-6641 , denotes ,
T19366 6635-6640 NNS denotes hours
T19365 6632-6634 CD denotes 36
T19364 6628-6631 IN denotes for
T19363 6622-6627 NN denotes IL-10
T19362 6616-6621 NN denotes ng/ml
T19361 6614-6615 CD denotes 1
T19360 6611-6613 IN denotes of
T19359 6603-6610 NN denotes absence
T19358 6600-6602 CC denotes or
T19357 6591-6599 NN denotes presence
T19356 6587-6590 DT denotes the
T19355 6584-6586 IN denotes in
T19354 6570-6583 NN denotes costimulation
T19353 6565-6569 NNP denotes CD28
T19352 6561-6564 CC denotes and
T19351 6557-6560 NNP denotes CD3
T19350 6554-6556 IN denotes by
T19349 6543-6553 VBN denotes stimulated
T19348 6538-6542 VBD denotes were
T19347 6532-6537 NNS denotes cells
T19346 6530-6531 NNP denotes T
T19345 6528-6529 CD denotes +
T19344 6525-6528 NNP denotes CD4
T19343 6518-6524 JJ denotes normal
T19342 6516-6517 , denotes ,
T19341 6511-6516 NNS denotes hours
T19340 6508-6510 CD denotes 36
T19339 6504-6507 IN denotes for
T19338 6499-6503 NN denotes IL-6
T19337 6493-6498 NN denotes ng/ml
T19336 6490-6492 CD denotes 10
T19335 6482-6489 IN denotes without
T19334 6479-6481 CC denotes or
T19333 6474-6478 IN denotes with
T19332 6460-6473 NN denotes preincubation
T19331 6454-6459 IN denotes After
T19330 6452-6453 . denotes .
T19329 6447-6452 NNS denotes cells
T19328 6445-6446 NNP denotes T
T19327 6443-6444 NNP denotes +
T19326 6440-6443 NNP denotes CD4
T19325 6437-6439 IN denotes by
T19324 6426-6436 NN denotes production
T19323 6420-6425 JJ denotes IFN-γ
T19322 6412-6419 VB denotes inhibit
T19321 6409-6411 TO denotes to
T19320 6403-6408 NN denotes IL-10
T19319 6400-6402 IN denotes of
T19318 6393-6399 NN denotes effect
T19317 6389-6392 DT denotes the
T19316 6380-6388 VB denotes suppress
T19315 6374-6379 MD denotes could
T19314 6369-6373 NN denotes IL-6
T19313 6361-6368 IN denotes whether
T19312 6352-6360 VBD denotes examined
T19311 6347-6351 JJ denotes next
T19310 6344-6346 PRP denotes We
T19309 6342-6343 . denotes .
T19308 6337-6342 NN denotes serum
T19307 6334-6336 NNP denotes RA
T19306 6331-6333 IN denotes in
T19305 6323-6330 JJ denotes present
T19304 6320-6322 VB denotes be
T19303 6316-6319 MD denotes may
T19302 6306-6315 VBG denotes signaling
T19301 6300-6305 CD denotes STAT1
T19300 6297-6299 IN denotes of
T19299 6286-6296 NNS denotes inhibitors
T19298 6281-6285 DT denotes that
T19297 6278-6280 CC denotes or
T19296 6276-6277 , denotes ,
T19295 6266-6276 NN denotes activation
T19294 6260-6265 CD denotes STAT3
T19293 6255-6259 IN denotes with
T19292 6246-6254 VBN denotes compared
T19291 6243-6245 IN denotes as
T19290 6232-6242 NN denotes activation
T19289 6226-6231 CD denotes STAT1
T19288 6222-6225 IN denotes for
T19287 6213-6221 VBN denotes required
T19286 6210-6212 VB denotes be
T19285 6206-6209 MD denotes may
T19284 6201-6205 NN denotes IL-6
T19283 6198-6200 IN denotes of
T19282 6183-6197 NNS denotes concentrations
T19281 6176-6182 JJR denotes higher
T19280 6171-6175 RB denotes much
T19279 6166-6170 IN denotes that
T19278 6157-6165 VBZ denotes suggests
T19277 6151-6156 NN denotes serum
T19276 6148-6150 NNP denotes RA
T19275 6145-6147 IN denotes by
T19274 6134-6144 NN denotes activation
T19273 6128-6133 CD denotes STAT1
T19272 6125-6127 IN denotes of
T19271 6120-6124 NN denotes lack
T19270 6116-6119 DT denotes The
T19269 6114-6115 . denotes .
T19268 6106-6114 NNS denotes patients
T19267 6103-6105 NNP denotes RA
T19266 6096-6102 JJ denotes active
T19265 6093-6095 IN denotes of
T19264 6088-6092 NN denotes sera
T19263 6085-6087 IN denotes in
T19262 6075-6084 VBN denotes contained
T19261 6068-6074 NN denotes factor
T19260 6051-6067 JJ denotes STAT3-activating
T19259 6042-6050 JJ denotes dominant
T19258 6038-6041 DT denotes the
T19257 6035-6037 VBZ denotes is
T19256 6030-6034 NNP denotes IL-6
T19255 6025-6029 IN denotes that
T19254 6016-6024 VBP denotes indicate
T19253 6008-6015 NNS denotes results
T19252 6002-6007 DT denotes These
T19251 6000-6001 . denotes .
T19250 5999-6000 -RRB- denotes )
T19249 5997-5999 CD denotes 5a
T19248 5992-5996 NNP denotes Fig.
T19247 5991-5992 -LRB- denotes (
T19246 5982-5990 NN denotes activity
T19245 5977-5981 NN denotes IL-6
T19244 5974-5976 IN denotes of
T19243 5959-5973 NN denotes neutralization
T19242 5956-5958 IN denotes by
T19241 5946-5955 VBN denotes abolished
T19240 5939-5945 RB denotes mostly
T19239 5935-5938 VBD denotes was
T19238 5924-5934 NN denotes activation
T19237 5918-5923 CD denotes STAT3
T19178 5591-5592 CD denotes 4
T19236 5913-5917 DT denotes this
T19235 5909-5912 CC denotes and
T19234 5907-5908 , denotes ,
T19233 5902-5907 NNP denotes STAT1
T19232 5898-5901 RB denotes not
T19231 5894-5897 CC denotes but
T19230 5888-5893 CD denotes STAT3
T19229 5885-5887 IN denotes of
T19228 5869-5884 NN denotes phosphorylation
T19227 5860-5868 JJ denotes tyrosine
T19226 5853-5859 VB denotes induce
T19225 5850-5852 TO denotes to
T19224 5845-5849 JJ denotes able
T19223 5841-5844 VBD denotes was
T19222 5835-5840 NN denotes serum
T19221 5832-5834 NNP denotes RA
T19220 5830-5831 . denotes .
T19219 5822-5830 NN denotes analysis
T19218 5817-5821 NN denotes blot
T19217 5809-5816 JJ denotes western
T19216 5806-5808 IN denotes by
T19215 5797-5805 VBN denotes examined
T19214 5793-5796 VBD denotes was
T19213 5777-5792 NN denotes phosphorylation
T19212 5772-5776 NNP denotes STAT
T19211 5768-5771 CC denotes and
T19210 5766-5767 , denotes ,
T19209 5758-5766 NN denotes antibody
T19208 5750-5757 NN denotes control
T19207 5747-5749 CC denotes or
T19206 5738-5746 NN denotes antibody
T19205 5728-5737 JJ denotes anti-IL-6
T19204 5715-5727 VBG denotes neutralizing
T19203 5711-5714 CC denotes and
T19202 5702-5710 NNS denotes patients
T19201 5699-5701 NNP denotes RA
T19200 5692-5698 JJ denotes active
T19199 5687-5691 IN denotes from
T19198 5681-5686 NN denotes serum
T19197 5679-5680 NN denotes %
T19196 5677-5679 CD denotes 30
T19195 5666-5676 VBG denotes containing
T19194 5659-5665 NN denotes medium
T19193 5651-5658 NN denotes culture
T19192 5646-5650 IN denotes with
T19191 5642-5645 NN denotes min
T19190 5639-5641 CD denotes 20
T19189 5635-5638 IN denotes for
T19188 5625-5634 VBN denotes incubated
T19187 5620-5624 RB denotes thus
T19186 5615-5619 VBD denotes were
T19185 5609-5614 NNS denotes cells
T19184 5607-5608 NNP denotes T
T19183 5605-5606 CD denotes +
T19182 5602-5605 NNP denotes CD4
T19181 5595-5601 JJ denotes Normal
T19180 5593-5594 . denotes .
T19179 5592-5593 NNP denotes ]
T19177 5590-5591 VBP denotes [
T19176 5577-5589 NNS denotes observations
T19175 5568-5576 JJ denotes previous
T19174 5563-5567 IN denotes with
T19173 5553-5562 NN denotes agreement
T19172 5550-5552 IN denotes in
T19171 5548-5549 , denotes ,
T19170 5547-5548 -RRB- denotes )
T19169 5542-5547 VBN denotes shown
T19168 5538-5541 RB denotes not
T19167 5533-5537 NNS denotes data
T19166 5532-5533 -LRB- denotes (
T19165 5526-5531 NNS denotes cells
T19164 5524-5525 NNP denotes T
T19163 5522-5523 CD denotes +
T19162 5519-5522 NNP denotes CD4
T19161 5512-5518 JJ denotes normal
T19160 5509-5511 IN denotes in
T19159 5504-5508 NN denotes IL-6
T19158 5501-5503 IN denotes by
T19157 5491-5500 VBN denotes activated
T19156 5487-5490 VBD denotes was
T19155 5471-5486 NN denotes phosphorylation
T19154 5465-5470 CD denotes STAT3
T19153 5461-5464 CC denotes and
T19152 5455-5460 CD denotes STAT1
T19151 5450-5454 DT denotes Both
T19150 5448-5449 . denotes .
T19149 5446-5448 NNP denotes RA
T19148 5439-5445 JJ denotes active
T19147 5436-5438 IN denotes in
T19146 5425-5435 NN denotes inhibition
T19145 5419-5424 NNP denotes IL-10
T19144 5416-5418 TO denotes to
T19143 5405-5415 NN denotes resistance
T19142 5401-5404 CC denotes and
T19141 5390-5400 NN denotes activation
T19140 5384-5389 CD denotes STAT3
T19139 5374-5383 VBN denotes sustained
T19138 5368-5373 PRP$ denotes their
T19137 5364-5367 IN denotes for
T19136 5352-5363 JJ denotes responsible
T19135 5348-5351 VBD denotes was
T19134 5336-5347 NN denotes circulation
T19133 5330-5335 NN denotes blood
T19132 5326-5329 DT denotes the
T19131 5323-5325 IN denotes in
T19130 5318-5322 NN denotes IL-6
T19129 5315-5317 IN denotes of
T19128 5300-5314 NNS denotes concentrations
T19127 5295-5299 JJ denotes high
T19126 5292-5294 TO denotes to
T19125 5286-5291 NNS denotes cells
T19124 5284-5285 NNP denotes T
T19123 5282-5283 CD denotes +
T19122 5279-5282 CD denotes CD4
T19121 5276-5278 IN denotes of
T19120 5267-5275 NN denotes exposure
T19119 5256-5266 JJ denotes persistent
T19118 5248-5255 IN denotes whether
T19117 5239-5247 VBD denotes examined
T19116 5236-5238 PRP denotes we
T19115 5234-5235 , denotes ,
T19114 5233-5234 NNP denotes ]
T19113 5231-5233 CD denotes 27
T19112 5230-5231 NNP denotes [
T19111 5224-5229 VBN denotes ng/ml
T19110 5222-5223 CD denotes 1
T19109 5220-5221 CD denotes >
T19108 5217-5219 IN denotes at
T19107 5208-5216 VBN denotes detected
T19106 5197-5207 RB denotes frequently
T19105 5195-5196 , denotes ,
T19104 5187-5195 NNS denotes patients
T19103 5184-5186 NNP denotes RA
T19102 5177-5183 JJ denotes active
T19101 5174-5176 IN denotes of
T19100 5169-5173 NN denotes sera
T19099 5166-5168 IN denotes in
T19098 5157-5165 JJ denotes abundant
T19097 5152-5156 RB denotes also
T19096 5149-5151 VBZ denotes is
T19095 5144-5148 NNP denotes IL-6
T19094 5138-5143 IN denotes Since
T19093 5136-5137 . denotes .
T19092 5135-5136 NNP denotes ]
T19091 5133-5135 CD denotes 31
T19090 5132-5133 NNP denotes [
T19089 5126-5131 NNS denotes cells
T19088 5114-5125 NN denotes mononuclear
T19087 5111-5113 IN denotes in
T19086 5105-5110 CD denotes STAT3
T19085 5102-5104 IN denotes of
T19084 5091-5101 NN denotes activation
T19083 5078-5090 JJ denotes constitutive
T19082 5070-5077 VBZ denotes induces
T19081 5065-5069 WDT denotes that
T19080 5059-5064 NN denotes fluid
T19079 5050-5058 JJ denotes synovial
T19078 5047-5049 NNP denotes RA
T19077 5044-5046 IN denotes in
T19076 5037-5043 NN denotes factor
T19075 5031-5036 JJ denotes major
T19074 5027-5030 DT denotes the
T19073 5024-5026 VBZ denotes is
T19072 5019-5023 NNP denotes IL-6
T19071 5014-5018 IN denotes that
T19070 5001-5013 VBN denotes demonstrated
T19069 4996-5000 VBP denotes have
T19068 4988-4995 NNS denotes studies
T19067 4979-4987 JJ denotes previous
T19066 4975-4978 CC denotes but
T19065 4973-4974 , denotes ,
T19064 4972-4973 NNP denotes ]
T19063 4971-4972 CD denotes 4
T19062 4970-4971 NNP denotes [
T19061 4964-4969 NNP denotes IL-10
T19060 4961-4963 TO denotes to
T19059 4952-4960 NN denotes addition
T19058 4949-4951 IN denotes in
T19057 4947-4948 , denotes ,
T19056 4941-4947 NN denotes factor
T19055 4934-4940 NN denotes growth
T19054 4924-4933 JJ denotes epidermal
T19053 4920-4923 CC denotes and
T19052 4918-4919 , denotes ,
T19051 4912-4918 NN denotes factor
T19050 4905-4911 NN denotes growth
T19049 4888-4904 JJ denotes platelet-derived
T19048 4886-4887 , denotes ,
T19047 4885-4886 -RRB- denotes )
T19046 4884-4885 NNP denotes M
T19024 4761-4770 NNS denotes cytokines
T19023 4756-4760 JJ denotes many
T19022 4753-4755 IN denotes by
T19021 4743-4752 VBN denotes activated
T19020 4740-4742 VBZ denotes is
T19019 4734-4739 NNP denotes STAT3
T19018 4728-4733 NNS denotes cells
T19017 4726-4727 NNP denotes T
T19016 4724-4725 CD denotes +
T19015 4721-4724 NNP denotes CD4
T19014 4714-4720 JJ denotes normal
T19013 4711-4713 IN denotes in
T19012 4704-4710 NN denotes effect
T19011 4698-4703 JJ denotes IL-10
T19010 4695-4697 IN denotes of
T19009 4684-4694 NN denotes inhibition
T19008 4680-4683 CC denotes and
T19007 4664-4679 NN denotes phosphorylation
T19006 4658-4663 CD denotes STAT3
T19005 4644-4657 JJ denotes IL-6-mediated
T19045 4873-4883 NN denotes oncostatin
T19044 4869-4872 CC denotes and
T19043 4867-4868 , denotes ,
T19042 4861-4867 NN denotes factor
T19041 4850-4860 JJ denotes inhibitory
T19040 4841-4849 NN denotes leukemia
T19039 4839-4840 , denotes ,
T19038 4834-4839 NNP denotes IL-11
T19037 4832-4833 , denotes ,
T19036 4828-4832 NNP denotes IL-6
T19035 4827-4828 -LRB- denotes (
T19034 4817-4826 NNS denotes cytokines
T19033 4814-4816 IN denotes of
T19032 4807-4813 NN denotes family
T19031 4802-4806 NNP denotes IL-6
T19030 4798-4801 DT denotes the
T19029 4795-4797 IN denotes as
T19028 4790-4794 JJ denotes such
T19027 4782-4789 NNS denotes factors
T19026 4775-4781 NN denotes growth
T19025 4771-4774 CC denotes and
T16744 4641-4642 . denotes .
T16743 4626-4641 NN denotes phosphorylation
T16742 4620-4625 NNP denotes STAT3
T16741 4610-4619 VBN denotes sustained
T16740 4605-4609 IN denotes with
T16739 4593-4604 NN denotes association
T16738 4590-4592 IN denotes in
T16737 4588-4589 , denotes ,
T16736 4586-4588 NNP denotes RA
T16735 4579-4585 JJ denotes active
T16734 4576-4578 IN denotes in
T16733 4565-4575 VBN denotes diminished
T16732 4562-4564 VB denotes be
T16731 4558-4561 MD denotes may
T16730 4547-4557 NN denotes activation
T16729 4541-4546 CD denotes STAT3
T16728 4527-4540 JJ denotes IL-10-induced
T16727 4523-4526 CC denotes and
T16726 4521-4522 , denotes ,
T16725 4516-4521 NNS denotes cells
T16724 4514-4515 NNP denotes T
T16723 4512-4513 NNP denotes +
T16722 4509-4512 NNP denotes CD4
T16721 4506-4508 IN denotes in
T16720 4501-4505 NNP denotes STAT
T16719 4485-4500 JJ denotes IL-10-activated
T16718 4479-4484 JJ denotes major
T16717 4475-4478 DT denotes the
T16716 4472-4474 VBZ denotes is
T16715 4466-4471 CD denotes STAT3
T16714 4461-4465 IN denotes that
T16713 4452-4460 VBP denotes indicate
T16712 4444-4451 NNS denotes results
T16711 4438-4443 DT denotes These
T16710 4436-4437 . denotes .
T16709 4435-4436 -RRB- denotes )
T16708 4433-4435 CD denotes 4a
T16707 4428-4432 NNP denotes Fig.
T16706 4427-4428 -LRB- denotes (
T16705 4421-4426 NNS denotes cells
T16704 4419-4420 NNP denotes T
T16703 4417-4418 CD denotes +
T16702 4414-4417 NNP denotes CD4
T16701 4407-4413 JJ denotes normal
T16700 4404-4406 CC denotes or
T16699 4398-4403 NNS denotes cells
T16698 4396-4397 NNP denotes T
T16697 4394-4395 VBD denotes +
T16696 4391-4394 NNP denotes CD4
T16695 4388-4390 NNP denotes RA
T16694 4381-4387 DT denotes either
T16693 4378-4380 IN denotes in
T16692 4369-4377 VBN denotes detected
T16691 4365-4368 RB denotes not
T16690 4361-4364 VBD denotes was
T16689 4345-4360 NN denotes phosphorylation
T16688 4339-4344 CD denotes STAT1
T16687 4325-4338 JJ denotes IL-10-induced
T16686 4323-4324 , denotes ,
T16685 4319-4323 NN denotes hand
T16684 4313-4318 JJ denotes other
T16683 4309-4312 DT denotes the
T16682 4306-4308 IN denotes On
T16681 4304-4305 . denotes .
T16680 4303-4304 -RRB- denotes )
T16679 4301-4303 CD denotes 4c
T16678 4296-4300 NNP denotes Fig.
T16677 4295-4296 -LRB- denotes (
T16676 4289-4294 NNS denotes cells
T16675 4287-4288 NNP denotes T
T16674 4285-4286 VBD denotes +
T16673 4282-4285 NNP denotes CD4
T16672 4279-4281 NNP denotes ST
T16671 4276-4278 NNP denotes RA
T16670 4273-4275 IN denotes in
T16669 4267-4272 VBN denotes found
T16668 4262-4266 VBD denotes were
T16667 4246-4261 NN denotes phosphorylation
T16666 4240-4245 CD denotes STAT3
T16665 4226-4239 JJ denotes IL-10-induced
T16664 4216-4225 JJ denotes defective
T16663 4212-4215 CC denotes and
T16662 4196-4211 NN denotes phosphorylation
T16661 4190-4195 CD denotes STAT3
T16660 4180-4189 VBN denotes sustained
T16659 4175-4179 DT denotes Both
T16658 4173-4174 . denotes .
T16657 4168-4173 NN denotes IL-10
T16656 4162-4167 NN denotes ng/ml
T16655 4159-4161 CD denotes 10
T16654 4156-4158 IN denotes as
T16653 4151-4155 JJ denotes much
T16652 4148-4150 RB denotes as
T16651 4145-4147 IN denotes by
T16650 4135-4144 VBN denotes activated
T16649 4130-4134 WRB denotes when
T16648 4125-4129 RB denotes only
T16647 4115-4124 VBN denotes augmented
T16646 4111-4114 VBD denotes was
T16645 4095-4110 NN denotes phosphorylation
T16644 4089-4094 CD denotes STAT3
T16643 4087-4088 . denotes .
T16642 4082-4087 NNS denotes hours
T16641 4080-4081 CD denotes 6
T16640 4077-4079 TO denotes to
T16639 4074-4076 RB denotes up
T16638 4070-4073 IN denotes for
T16637 4059-4069 JJ denotes detectable
T16636 4055-4058 VBD denotes was
T16635 4039-4054 NN denotes phosphorylation
T16634 4033-4038 CD denotes STAT3
T16633 4028-4032 DT denotes this
T16632 4024-4027 CC denotes and
T16631 4015-4023 NNS denotes patients
T16630 4012-4014 NNP denotes RA
T16629 4007-4011 IN denotes from
T16628 4001-4006 NNS denotes cells
T16627 3999-4000 VBD denotes +
T16626 3996-3999 NNP denotes CD4
T16625 3993-3995 NNP denotes PB
T16624 3984-3992 VBN denotes isolated
T16623 3976-3983 RB denotes freshly
T16622 3973-3975 IN denotes in
T16621 3958-3972 VBN denotes phosphorylated
T16620 3954-3957 VBD denotes was
T16619 3948-3953 NNP denotes STAT3
T16618 3946-3947 , denotes ,
T16617 3938-3946 NN denotes contrast
T16616 3935-3937 IN denotes In
T16615 3933-3934 . denotes .
T16614 3932-3933 -RRB- denotes )
T16613 3931-3932 NN denotes b
T16612 3929-3931 CD denotes ,4
T16611 3927-3929 CD denotes 4a
T16610 3922-3926 NNP denotes Fig.
T16609 3921-3922 -LRB- denotes (
T16608 3915-3920 NNS denotes cells
T16607 3913-3914 NNP denotes T
T16606 3911-3912 CD denotes +
T16605 3908-3911 NNP denotes CD4
T16604 3901-3907 JJ denotes normal
T16603 3898-3900 IN denotes in
T16602 3894-3897 NN denotes min
T16601 3891-3893 CD denotes 20
T16600 3887-3890 IN denotes for
T16599 3876-3886 NN denotes activation
T16598 3870-3875 NNP denotes IL-10
T16597 3864-3869 IN denotes after
T16596 3856-3863 VBN denotes induced
T16595 3839-3855 RB denotes dose-dependently
T16594 3835-3838 VBD denotes was
T16593 3819-3834 NN denotes phosphorylation
T16592 3813-3818 CD denotes STAT3
T16591 3811-3812 . denotes .
T16590 3803-3811 VBG denotes blotting
T16589 3795-3802 JJ denotes western
T16588 3789-3794 VBG denotes using
T16587 3780-3788 VBN denotes examined
T16586 3776-3779 VBD denotes was
T16585 3767-3775 NNS denotes controls
T16584 3759-3766 JJ denotes healthy
T16583 3754-3758 IN denotes from
T16582 3750-3753 CC denotes and
T16581 3741-3749 NNS denotes patients
T16580 3738-3740 NNP denotes RA
T16579 3731-3737 JJ denotes active
T16578 3726-3730 IN denotes from
T16577 3720-3725 NNS denotes cells
T16576 3718-3719 NNP denotes T
T16575 3716-3717 VBD denotes +
T16574 3713-3716 NNP denotes CD4
T16573 3710-3712 NNP denotes PB
T16572 3707-3709 IN denotes in
T16571 3701-3706 NNP denotes IL-10
T16570 3698-3700 IN denotes by
T16569 3682-3697 NN denotes phosphorylation
T16568 3676-3681 CD denotes STAT3
T16567 3672-3675 CC denotes and
T16566 3666-3671 CD denotes STAT1
T16565 3663-3665 IN denotes of
T16564 3653-3662 NN denotes induction
T16563 3649-3652 DT denotes The
T16562 3647-3648 . denotes .
T16561 3646-3647 NNP denotes ]
T16560 3644-3646 CD denotes 30
T16559 3643-3644 NNP denotes [
T16558 3628-3642 NN denotes overexpression
T16556 3604-3621 JJ denotes dominant-negative
T16555 3601-3603 IN denotes of
T16554 3593-3600 NNS denotes studies
T16553 3590-3592 IN denotes by
T16552 3578-3589 NNS denotes macrophages
T16551 3572-3577 JJ denotes human
T16550 3569-3571 IN denotes in
T16549 3559-3568 VBN denotes confirmed
T16548 3554-3558 VBN denotes been
T16547 3545-3553 RB denotes recently
T16546 3541-3544 VBZ denotes has
T16545 3535-3540 WDT denotes which
T16544 3533-3534 , denotes ,
T16543 3532-3533 NNP denotes ]
T16542 3531-3532 CD denotes 5
T16541 3530-3531 VBP denotes [
T16540 3520-3529 NNS denotes responses
T16539 3502-3519 JJ denotes anti-inflammatory
T16538 3487-3501 JJ denotes IL-10-mediated
T16537 3484-3486 IN denotes in
T16536 3479-3483 NN denotes role
T16535 3470-3478 JJ denotes dominant
T16534 3468-3469 DT denotes a
T16533 3462-3467 VBZ denotes plays
T16532 3456-3461 CD denotes STAT3
T16531 3451-3455 IN denotes that
T16530 3438-3450 VBD denotes demonstrated
T16529 3433-3437 NNS denotes mice
T16528 3417-3432 JJ denotes STAT3-deficient
T16527 3397-3416 JJ denotes Macrophage-specific
T16526 3395-3396 . denotes .
T16525 3394-3395 NNP denotes ]
T16524 3393-3394 CD denotes 3
T16523 3392-3393 NNP denotes [
T16522 3386-3391 NNP denotes STAT3
T16521 3382-3385 CC denotes and
T16520 3376-3381 NNP denotes STAT1
T16519 3368-3375 NNS denotes factors
T16518 3354-3367 NN denotes transcription
T16517 3347-3353 NN denotes latent
T16516 3343-3346 DT denotes the
T16515 3340-3342 IN denotes of
T16514 3329-3339 NN denotes activation
T16513 3325-3328 CC denotes and
T16512 3309-3324 NN denotes phosphorylation
T16511 3300-3308 NN denotes tyrosine
T16510 3292-3299 VBZ denotes induces
T16509 3286-3291 JJ denotes IL-10
T16508 3281-3285 IN denotes with
T16507 3274-3280 NN denotes IL-10R
T16506 3271-3273 IN denotes of
T16505 3259-3270 NN denotes interaction
T16504 3255-3258 DT denotes The
T16503 3249-3254 NNS denotes cells
T16502 3247-3248 NNP denotes T
T16501 3245-3246 VBD denotes +
T16500 3242-3245 NNP denotes CD4
T16499 3239-3241 NNP denotes RA
T16498 3236-3238 IN denotes in
T16497 3220-3235 NN denotes phosphorylation
T16496 3214-3219 CD denotes STAT3
T16495 3199-3213 JJ denotes IL-10-mediated
T16494 3189-3198 JJ denotes Defective
T16557 3622-3627 CD denotes STAT3
T15171 3060-3065 DT denotes These
T15170 3058-3059 . denotes .
T15169 3050-3058 NNS denotes controls
T15168 3042-3049 JJ denotes healthy
T15167 3039-3041 IN denotes in
T15166 3034-3038 IN denotes with
T15165 3025-3033 VBN denotes compared
T15164 3016-3024 NNS denotes patients
T15163 3013-3015 NNP denotes RA
T15162 3010-3012 IN denotes in
T15161 3000-3009 VBN denotes increased
T15160 2986-2999 RB denotes significantly
T15159 2982-2985 VBD denotes was
T15158 2976-2981 NNS denotes cells
T15157 2974-2975 NNP denotes T
T15156 2972-2973 NNP denotes +
T15155 2969-2972 NNP denotes CD4
T15154 2966-2968 IN denotes on
T15153 2955-2965 NN denotes expression
T15152 2947-2954 NN denotes IL-10R1
T15151 2944-2946 IN denotes of
T15150 2934-2943 NN denotes intensity
T15149 2930-2933 DT denotes the
T15148 2928-2929 , denotes ,
T15147 2927-2928 NN denotes b
T15146 2925-2927 CD denotes ,3
T15145 2923-2925 CD denotes 3a
T15144 2918-2922 NNP denotes Fig.
T15143 2915-2917 IN denotes in
T15142 2909-2914 VBN denotes shown
T15141 2906-2908 IN denotes As
T15140 2904-2905 . denotes .
T15139 2896-2904 NN denotes analysis
T15138 2885-2895 JJ denotes cytometric
T15137 2880-2884 NN denotes flow
T15136 2877-2879 IN denotes by
T15135 2866-2876 VBN denotes determined
T15134 2862-2865 VBD denotes was
T15133 2853-2861 NNS denotes controls
T15132 2845-2852 JJ denotes healthy
T15131 2840-2844 IN denotes from
T15130 2836-2839 CC denotes and
T15129 2827-2835 NNS denotes patients
T15128 2824-2826 NNP denotes RA
T15127 2817-2823 JJ denotes active
T15126 2812-2816 IN denotes from
T15125 2806-2811 NNS denotes cells
T15124 2804-2805 NNP denotes T
T15123 2802-2803 VBD denotes +
T15122 2799-2802 NNP denotes CD4
T15121 2796-2798 NNP denotes PB
T15120 2793-2795 IN denotes on
T15119 2785-2792 NN denotes IL-10R1
T15118 2782-2784 IN denotes of
T15117 2771-2781 NN denotes expression
T15116 2763-2770 NN denotes surface
T15115 2758-2762 NN denotes cell
T15114 2754-2757 DT denotes the
T15113 2752-2753 , denotes ,
T15112 2742-2752 NN denotes expression
T15111 2733-2741 NN denotes receptor
T15110 2725-2732 JJ denotes limited
T15109 2722-2724 TO denotes to
T15108 2718-2721 JJ denotes due
T15107 2714-2717 VBD denotes was
T15106 2708-2713 NNS denotes cells
T15105 2706-2707 NNP denotes T
T15104 2704-2705 VBD denotes +
T15103 2701-2704 NNP denotes CD4
T15102 2698-2700 NNP denotes RA
T15101 2695-2697 IN denotes in
T15100 2684-2694 NN denotes inhibition
T15099 2678-2683 NNP denotes IL-10
T15098 2675-2677 TO denotes to
T15097 2664-2674 NN denotes resistance
T15096 2660-2663 DT denotes the
T15095 2652-2659 IN denotes whether
T15094 2644-2651 VB denotes examine
T15093 2641-2643 TO denotes To
T15092 2639-2640 . denotes .
T15091 2638-2639 NNP denotes ]
T15090 2636-2638 CD denotes 29
T15089 2635-2636 NNP denotes [
T15088 2629-2634 NNP denotes IL-10
T15087 2626-2628 TO denotes to
T15086 2616-2625 NNS denotes responses
T15085 2607-2615 JJ denotes cellular
T15084 2604-2606 IN denotes in
T15083 2599-2603 NN denotes role
T15082 2590-2598 JJ denotes critical
T15081 2588-2589 DT denotes a
T15080 2582-2587 VBZ denotes plays
T15079 2571-2581 NN denotes expression
T15078 2563-2570 CD denotes IL-10R1
T15077 2561-2562 . denotes .
T15076 2560-2561 NNP denotes ]
T15075 2559-2560 CD denotes 1
T15074 2558-2559 NNP denotes [
T15073 2551-2557 NNP denotes IL-10R
T15072 2549-2550 CD denotes 2
T15071 2544-2548 NN denotes type
T15070 2534-2543 NN denotes component
T15069 2524-2533 JJ denotes accessory
T15068 2520-2523 DT denotes the
T15067 2516-2519 CC denotes and
T15066 2508-2515 NN denotes IL-10R1
T15065 2498-2507 NN denotes component
T15064 2483-2497 JJ denotes ligand-binding
T15063 2475-2482 JJ denotes primary
T15062 2471-2474 DT denotes the
T15061 2469-2470 , denotes ,
T15060 2461-2469 NNS denotes subunits
T15059 2457-2460 CD denotes two
T15058 2454-2456 IN denotes of
T15057 2445-2453 VBZ denotes consists
T15056 2439-2444 NN denotes IL-10
T15055 2436-2438 IN denotes of
T15054 2428-2435 NN denotes complex
T15053 2419-2427 NN denotes receptor
T15052 2408-2418 JJ denotes functional
T15051 2404-2407 DT denotes The
T15050 2398-2403 NNS denotes cells
T15049 2396-2397 NNP denotes T
T15048 2394-2395 VBD denotes +
T15047 2391-2394 NNP denotes CD4
T15046 2388-2390 NNP denotes RA
T15045 2385-2387 IN denotes on
T15044 2377-2384 NN denotes IL-10R1
T15043 2369-2376 NN denotes surface
T15042 2364-2368 NN denotes cell
T15041 2361-2363 IN denotes of
T15040 2350-2360 NN denotes expression
T15039 2340-2349 VBN denotes Increased
T15193 3186-3187 . denotes .
T15192 3184-3186 NNP denotes RA
T15191 3177-3183 JJ denotes active
T15190 3174-3176 IN denotes of
T15189 3168-3173 NNS denotes cells
T15188 3166-3167 NNP denotes T
T15187 3164-3165 CD denotes +
T15186 3161-3164 CD denotes CD4
T15185 3158-3160 IN denotes in
T15184 3149-3157 VBN denotes impaired
T15183 3146-3148 VB denotes be
T15182 3142-3145 MD denotes may
T15181 3136-3141 NN denotes IL-10
T15180 3133-3135 IN denotes of
T15179 3125-3132 NN denotes pathway
T15178 3112-3124 NN denotes transduction
T15177 3105-3111 NN denotes signal
T15176 3091-3104 JJ denotes intracellular
T15175 3087-3090 DT denotes the
T15174 3082-3086 IN denotes that
T15173 3074-3081 VBP denotes suggest
T13988 1824-1828 NNP denotes Fig.
T13987 1823-1824 -LRB- denotes (
T13986 1817-1822 NNS denotes cells
T13985 1815-1816 NNP denotes T
T13984 1813-1814 CD denotes +
T13983 1810-1813 NNP denotes CD4
T13982 1803-1809 JJ denotes normal
T13981 1799-1802 VBD denotes did
T13980 1794-1798 IN denotes than
T13979 1788-1793 NN denotes IL-10
T13978 1782-1787 NN denotes ng/ml
T13977 1780-1781 CD denotes 1
T13976 1777-1779 IN denotes of
T13975 1768-1776 NN denotes presence
T13974 1764-1767 DT denotes the
T13973 1761-1763 IN denotes in
T13972 1755-1760 NNP denotes IFN-γ
T13971 1752-1754 IN denotes of
T13970 1745-1751 NNS denotes levels
T13969 1738-1744 JJR denotes higher
T13968 1729-1737 VBD denotes produced
T13967 1720-1728 NNS denotes patients
T13966 1717-1719 NNP denotes RA
T13965 1710-1716 JJ denotes active
T13964 1705-1709 IN denotes from
T13963 1699-1704 NNS denotes cells
T13962 1697-1698 NNP denotes T
T13961 1695-1696 NNP denotes +
T13960 1692-1695 NNP denotes CD4
T13959 1690-1691 , denotes ,
T13958 1679-1690 NN denotes consequence
T13957 1677-1678 DT denotes a
T13956 1674-1676 IN denotes As
T13955 1672-1673 . denotes .
T13954 1671-1672 -RRB- denotes )
T13953 1669-1671 CD denotes 2b
T13952 1664-1668 NNP denotes Fig.
T13951 1663-1664 -LRB- denotes (
T13950 1661-1662 -RRB- denotes )
T13949 1660-1661 NN denotes %
T13948 1657-1660 CD denotes 7.9
T13947 1655-1656 NN denotes ±
T13946 1650-1654 CD denotes 65.8
T13945 1648-1649 , denotes ,
T13944 1640-1648 NNS denotes controls
T13943 1638-1639 : denotes ;
T13942 1637-1638 NN denotes %
T13941 1633-1637 CD denotes 14.4
T13940 1631-1632 NN denotes ±
T13939 1626-1630 CD denotes 45.6
T13938 1624-1625 , denotes ,
T13937 1622-1624 NNP denotes RA
T13936 1613-1621 JJ denotes inactive
T13935 1611-1612 : denotes ;
T13934 1610-1611 NN denotes %
T13933 1606-1610 CD denotes 14.4
T13932 1604-1605 NN denotes ±
T13931 1600-1603 CD denotes 2.9
T13930 1598-1599 , denotes ,
T13929 1596-1598 NNP denotes RA
T13928 1589-1595 JJ denotes active
T13927 1587-1588 : denotes :
T13926 1579-1587 NN denotes decrease
T13925 1568-1578 NN denotes percentage
T13924 1567-1568 -LRB- denotes (
T13923 1558-1566 NNS denotes controls
T13922 1550-1557 JJ denotes healthy
T13921 1546-1549 CC denotes and
T13920 1540-1545 NN denotes group
T13919 1537-1539 NNP denotes RA
T13918 1528-1536 JJ denotes inactive
T13917 1524-1527 DT denotes the
T13916 1519-1523 IN denotes with
T13915 1510-1518 VBN denotes compared
T13914 1507-1509 IN denotes as
T13913 1501-1506 NN denotes group
T13912 1498-1500 NNP denotes RA
T13911 1491-1497 JJ denotes active
T13910 1487-1490 DT denotes the
T13909 1484-1486 IN denotes in
T13908 1476-1483 VBN denotes limited
T13907 1462-1475 RB denotes significantly
T13906 1458-1461 VBD denotes was
T13905 1447-1457 NN denotes production
T13904 1441-1446 JJ denotes IFN-γ
T13903 1438-1440 IN denotes on
T13902 1432-1437 NN denotes IL-10
T13901 1429-1431 IN denotes of
T13900 1422-1428 NN denotes effect
T13899 1411-1421 JJ denotes inhibitory
T13898 1407-1410 DT denotes the
T13897 1403-1406 CC denotes but
T13896 1401-1402 , denotes ,
T13895 1400-1401 -RRB- denotes )
T13894 1398-1400 CD denotes 2a
T13893 1393-1397 NNP denotes Fig.
T13892 1392-1393 -LRB- denotes (
T13891 1385-1391 NNS denotes groups
T13890 1379-1384 CD denotes three
T13889 1373-1378 DT denotes these
T13888 1367-1372 IN denotes among
T13887 1361-1366 NN denotes IL-10
T13886 1353-1360 IN denotes without
T13885 1342-1352 NN denotes production
T13884 1336-1341 JJ denotes IFN-γ
T13883 1333-1335 IN denotes in
T13882 1321-1332 NNS denotes differences
T13881 1309-1320 JJ denotes significant
T13880 1295-1308 RB denotes statistically
T13879 1292-1294 DT denotes no
T13878 1287-1291 VBD denotes were
T13877 1281-1286 EX denotes There
T13876 1279-1280 . denotes .
T13875 1271-1279 NNS denotes controls
T13874 1263-1270 JJ denotes healthy
T13873 1260-1262 IN denotes in
T13872 1256-1259 CC denotes and
T13871 1254-1255 NNP denotes ]
T13870 1252-1254 CD denotes 26
T13869 1251-1252 NNP denotes [
T13868 1249-1250 -RRB- denotes )
T13867 1245-1249 NN denotes mg/l
T13866 1242-1244 CD denotes 10
T13865 1240-1241 NN denotes <
T13864 1234-1239 NN denotes level
T13863 1230-1233 NNP denotes CRP
T13862 1228-1229 , denotes ,
T13861 1219-1228 NN denotes remission
T13860 1216-1218 IN denotes in
T13859 1215-1216 -LRB- denotes (
T13858 1207-1214 NN denotes disease
T13857 1198-1206 JJ denotes inactive
T13856 1194-1197 CC denotes and
T13855 1192-1193 -RRB- denotes )
T13854 1188-1192 NN denotes mg/l
T13853 1185-1187 CD denotes 10
T13852 1183-1184 NN denotes ≥
T13851 1177-1182 NN denotes level
T13850 1173-1176 NNP denotes CRP
T13849 1171-1172 , denotes ,
T13848 1165-1171 NNS denotes joints
T13847 1152-1164 JJ denotes inflammatory
T13846 1143-1151 JJ denotes multiple
T13845 1142-1143 -LRB- denotes (
T13844 1134-1141 NN denotes disease
T13843 1127-1133 JJ denotes active
T13842 1122-1126 IN denotes with
T13841 1113-1121 NNS denotes patients
T13840 1110-1112 NNP denotes RA
T13839 1107-1109 IN denotes in
T13838 1101-1106 NN denotes IL-10
T13837 1095-1100 NN denotes ng/ml
T13836 1093-1094 CD denotes 1
T13835 1090-1092 IN denotes of
T13834 1081-1089 NN denotes presence
T13833 1077-1080 DT denotes the
T13832 1074-1076 IN denotes in
T13831 1060-1073 NN denotes costimulation
T13830 1055-1059 NNP denotes CD28
T13829 1051-1054 CC denotes and
T13828 1047-1050 NNP denotes CD3
T13827 1041-1046 IN denotes after
T13826 1035-1040 NNS denotes cells
T13825 1033-1034 NNP denotes T
T13824 1031-1032 NNP denotes +
T13823 1028-1031 NNP denotes CD4
T13822 1025-1027 IN denotes by
T13821 1014-1024 NN denotes production
T13820 1008-1013 JJ denotes IFN-γ
T13819 1005-1007 IN denotes of
T13818 998-1004 NNS denotes levels
T13817 994-997 DT denotes the
T13816 985-993 VBD denotes compared
T13815 980-984 RB denotes thus
T13814 977-979 PRP denotes We
T13813 975-976 . denotes .
T13812 970-975 NN denotes ng/ml
T13811 966-969 CD denotes 100
T13810 963-965 CD denotes 10
T13809 960-962 IN denotes at
T13808 951-959 VBN denotes obtained
T13807 947-950 VBD denotes was
T13806 941-946 NNP denotes IL-10
T13805 938-940 IN denotes by
T13804 927-937 NN denotes inhibition
T13803 918-926 JJ denotes complete
T13802 914-917 RB denotes not
T13801 910-913 CC denotes but
T13800 902-909 JJ denotes maximal
T13799 898-901 DT denotes the
T13798 894-897 CC denotes and
T13797 892-893 , denotes ,
T13796 887-892 NN denotes IL-10
T13795 881-886 NN denotes ng/ml
T13794 879-880 CD denotes 1
T13793 876-878 IN denotes of
T13792 867-875 NN denotes presence
T13791 863-866 DT denotes the
T13790 860-862 IN denotes in
T13789 854-859 NNP denotes IFN-γ
T13788 851-853 IN denotes of
T13787 843-850 NNS denotes amounts
T13786 831-842 JJ denotes significant
T13785 823-830 VB denotes produce
T13784 820-822 TO denotes to
T13783 815-819 JJ denotes able
T13782 810-814 VBD denotes were
T13781 804-809 NNS denotes cells
T13780 802-803 NNP denotes T
T13779 800-801 VBD denotes +
T13778 797-800 NNP denotes CD4
T13777 794-796 NNP denotes RA
T13776 792-793 , denotes ,
T13775 785-792 RB denotes However
T13774 783-784 . denotes .
T13773 778-783 NN denotes IL-10
T13713 431-437 JJ denotes active
T13712 426-430 IN denotes with
T13711 417-425 NNS denotes patients
T13710 411-416 CD denotes three
T13709 406-410 IN denotes from
T13708 400-405 NNS denotes cells
T13707 398-399 NNP denotes T
T13706 396-397 VBD denotes +
T13705 393-396 NNP denotes CD4
T13704 390-392 NNP denotes PB
T13703 381-389 VBD denotes purified
T13702 379-380 , denotes ,
T13701 374-379 NNP denotes IL-10
T13700 371-373 TO denotes to
T13699 365-370 NNS denotes cells
T13698 363-364 NNP denotes T
T13697 361-362 VBD denotes +
T13696 358-361 NNP denotes CD4
T13695 355-357 NNP denotes RA
T13694 352-354 IN denotes of
T13693 337-351 NN denotes responsiveness
T13692 333-336 DT denotes the
T13691 324-332 VB denotes evaluate
T13690 321-323 TO denotes To
T13689 319-320 . denotes .
T13688 318-319 NNP denotes ]
T13687 316-318 CD denotes 24
T13686 315-316 NNP denotes [
T13685 306-314 JJ denotes 3-kinase
T13684 285-305 NN denotes phosphatidylinositol
T13683 282-284 IN denotes of
T13682 274-281 JJ denotes binding
T13681 270-273 CC denotes and
T13680 254-269 NN denotes phosphorylation
T13679 245-253 NN denotes tyrosine
T13678 240-244 NNP denotes CD28
T13677 229-239 VBG denotes inhibiting
T13676 226-228 IN denotes by
T13675 217-225 NN denotes response
T13674 212-216 DT denotes this
T13673 203-211 VB denotes suppress
T13672 194-202 RB denotes directly
T13671 190-193 MD denotes can
T13670 184-189 NNP denotes IL-10
T13669 180-183 CC denotes and
T13668 178-179 , denotes ,
T13667 168-178 NN denotes production
T13666 159-167 NN denotes cytokine
T13665 152-158 NN denotes T-cell
T13664 135-151 JJ denotes antigen-specific
T13663 125-134 JJ denotes effective
T13662 121-124 IN denotes for
T13661 113-120 JJ denotes crucial
T13660 110-112 VBZ denotes is
T13659 102-109 NN denotes pathway
T13658 88-101 JJ denotes costimulatory
T13657 83-87 CD denotes CD28
T13656 79-82 DT denotes The
T13655 73-78 NNS denotes cells
T13654 71-72 NNP denotes T
T13653 69-70 VBD denotes +
T13652 66-69 NNP denotes CD4
T13651 63-65 NNP denotes RA
T13650 60-62 IN denotes in
T13649 49-59 NN denotes production
T13648 43-48 JJ denotes IFN-γ
T13647 40-42 IN denotes of
T13646 29-39 NN denotes inhibition
T13645 23-28 NNP denotes IL-10
T13644 20-22 TO denotes to
T13643 9-19 NN denotes Resistance
T14091 2337-2338 . denotes .
T14090 2332-2337 NN denotes phase
T14089 2325-2331 JJ denotes active
T14088 2321-2324 DT denotes the
T14087 2314-2320 IN denotes during
T14086 2308-2313 NN denotes IL-10
T14085 2305-2307 IN denotes of
T14084 2298-2304 NN denotes effect
T14083 2281-2297 JJ denotes immunoregulatory
T14082 2277-2280 DT denotes the
T14081 2274-2276 TO denotes to
T14080 2262-2273 JJ denotes susceptible
T14079 2257-2261 RBR denotes less
T14078 2250-2256 VBP denotes become
T14077 2244-2249 NNS denotes cells
T14076 2242-2243 NNP denotes T
T14075 2240-2241 VBD denotes +
T14074 2237-2240 NNP denotes CD4
T14073 2234-2236 NNP denotes RA
T14072 2229-2233 IN denotes that
T14071 2220-2228 VBP denotes indicate
T14070 2212-2219 NNS denotes results
T14069 2206-2211 DT denotes these
T14068 2204-2205 , denotes ,
T14067 2196-2204 RB denotes together
T14066 2190-2195 VBN denotes Taken
T14065 2188-2189 . denotes .
T14064 2187-2188 -RRB- denotes )
T14063 2183-2187 CD denotes 0.05
T14062 2181-2182 NNP denotes <
T14061 2179-2180 NNP denotes P
T14060 2177-2178 : denotes ;
T14059 2176-2177 NN denotes %
T14058 2172-2176 CD denotes 13.7
T14057 2170-2171 CD denotes ±
T14056 2165-2169 CD denotes 61.1
T14055 2164-2165 -LRB- denotes (
T14054 2155-2163 NNS denotes controls
T14053 2147-2154 JJ denotes healthy
T14052 2144-2146 IN denotes in
T14051 2136-2143 VBN denotes reduced
T14050 2122-2135 RB denotes significantly
T14049 2118-2121 VBD denotes was
T14048 2115-2117 PRP denotes it
T14047 2109-2114 IN denotes while
T14046 2107-2108 , denotes ,
T14045 2106-2107 -RRB- denotes )
T14044 2105-2106 NN denotes %
T14043 2101-2105 CD denotes 13.8
T14042 2099-2100 NN denotes ±
T14041 2094-2098 CD denotes -2.1
T14040 2092-2093 , denotes ,
T14039 2084-2092 NN denotes decrease
T14038 2073-2083 NN denotes percentage
T14037 2072-2073 -LRB- denotes (
T14036 2063-2071 NNS denotes patients
T14035 2060-2062 NNP denotes RA
T14034 2057-2059 IN denotes in
T14033 2051-2056 NN denotes IL-10
T14032 2045-2050 NN denotes ng/ml
T14031 2043-2044 CD denotes 1
T14030 2040-2042 IN denotes by
T14029 2031-2039 VBN denotes affected
T14028 2027-2030 RB denotes not
T14027 2023-2026 VBD denotes was
T14026 2012-2022 NN denotes production
T14025 2007-2011 JJ denotes IL-2
T14024 2005-2006 , denotes ,
T14023 1996-2005 RB denotes Similarly
T14022 1994-1995 . denotes .
T14021 1986-1994 NNS denotes controls
T14020 1978-1985 JJ denotes healthy
T14019 1975-1977 IN denotes in
T14018 1971-1974 CC denotes and
T14017 1962-1970 NNS denotes patients
T14016 1959-1961 NNP denotes RA
T14015 1952-1958 JJ denotes active
T14014 1949-1951 IN denotes in
T14013 1943-1948 NN denotes IL-10
T14012 1940-1942 IN denotes of
T14011 1931-1939 NN denotes presence
T14010 1927-1930 DT denotes the
T14009 1924-1926 IN denotes in
T14008 1910-1923 NN denotes costimulation
T14007 1905-1909 NNP denotes CD28
T14006 1901-1904 CC denotes and
T14005 1897-1900 NNP denotes CD3
T14004 1891-1896 IN denotes after
T14003 1885-1890 NNS denotes cells
T14002 1883-1884 NNP denotes T
T14001 1881-1882 NNP denotes +
T14000 1878-1881 NNP denotes CD4
T13999 1875-1877 IN denotes by
T13998 1864-1874 NN denotes production
T13997 1859-1863 JJ denotes IL-2
T13996 1850-1858 VBD denotes compared
T13995 1847-1849 PRP denotes we
T13994 1845-1846 , denotes ,
T13993 1837-1845 NN denotes addition
T13992 1834-1836 IN denotes In
T13991 1832-1833 . denotes .
T13990 1831-1832 -RRB- denotes )
T13989 1829-1831 CD denotes 2a
T13772 772-777 NN denotes ng/ml
T13771 770-771 CD denotes 1
T13770 767-769 IN denotes as
T13769 763-766 JJ denotes low
T13768 760-762 RB denotes as
T13767 745-759 NNS denotes concentrations
T13766 742-744 IN denotes at
T13765 732-741 VBN denotes inhibited
T13764 725-731 RB denotes mostly
T13763 721-724 VBD denotes was
T13762 715-720 NNS denotes cells
T13761 713-714 NNP denotes T
T13760 711-712 CD denotes +
T13759 708-711 NNP denotes CD4
T13758 701-707 JJ denotes normal
T13757 691-700 VBN denotes activated
T13756 688-690 IN denotes by
T13755 677-687 NN denotes production
T13754 671-676 JJ denotes IFN-γ
T13753 669-670 , denotes ,
T13752 668-669 CD denotes 1
T13751 663-667 NNP denotes Fig.
T13750 660-662 IN denotes in
T13749 654-659 VBN denotes shown
T13748 651-653 IN denotes As
T13747 649-650 . denotes .
T13746 644-649 NNP denotes ELISA
T13745 641-643 IN denotes by
T13744 632-640 VBN denotes measured
T13743 628-631 VBD denotes was
T13742 617-627 NN denotes production
T13741 611-616 JJ denotes IFN-γ
T13740 607-610 CC denotes and
T13739 605-606 , denotes ,
T13738 600-605 NNS denotes hours
T13737 597-599 CD denotes 36
T13736 593-596 IN denotes for
T13735 587-592 NN denotes IL-10
T13734 584-586 IN denotes of
T13733 569-583 NNS denotes concentrations
T13732 561-568 VBN denotes diluted
T13731 553-560 IN denotes without
T13730 550-552 CC denotes or
T13729 545-549 IN denotes with
T13728 536-544 NN denotes antibody
T13727 526-535 JJ denotes anti-CD28
T13726 522-525 CC denotes and
T13725 513-521 NN denotes antibody
T13724 504-512 JJ denotes anti-CD3
T13723 492-503 JJ denotes immobilized
T13722 489-491 IN denotes by
T13721 478-488 VBN denotes stimulated
T13720 473-477 VBD denotes were
T13719 464-472 NNS denotes controls
T13718 456-463 JJ denotes healthy
T13717 450-455 CD denotes three
T13716 445-449 IN denotes from
T13715 441-444 CC denotes and
T13714 438-440 NNP denotes RA
R6873 T13643 T13643 ROOT Resistance,Resistance
R6874 T13644 T13643 prep to,Resistance
R6875 T13645 T13644 pobj IL-10,to
R6876 T13646 T13643 conj inhibition,Resistance
R6877 T13647 T13646 prep of,inhibition
R6878 T13648 T13649 amod IFN-γ,production
R6879 T13649 T13647 pobj production,of
R6880 T13650 T13649 prep in,production
R6881 T13651 T13652 compound RA,CD4
R6882 T13652 T13650 pobj CD4,in
R6883 T13653 T13655 amod +,cells
R6884 T13654 T13655 compound T,cells
R6885 T13655 T13643 appos cells,Resistance
R6886 T13656 T13659 det The,pathway
R6887 T13657 T13659 nummod CD28,pathway
R6888 T13658 T13659 amod costimulatory,pathway
R6889 T13659 T13660 nsubj pathway,is
R6890 T13660 T13660 ROOT is,is
R6891 T13661 T13660 acomp crucial,is
R6892 T13662 T13661 prep for,crucial
R6893 T13663 T13667 amod effective,production
R6894 T13664 T13667 amod antigen-specific,production
R6895 T13665 T13667 nmod T-cell,production
R6896 T13666 T13667 compound cytokine,production
R6897 T13667 T13662 pobj production,for
R6898 T13668 T13660 punct ",",is
R6899 T13669 T13660 cc and,is
R6900 T13670 T13673 nsubj IL-10,suppress
R6901 T13671 T13673 aux can,suppress
R6902 T13672 T13673 advmod directly,suppress
R6903 T13673 T13660 conj suppress,is
R6904 T13674 T13675 det this,response
R6905 T13675 T13673 dobj response,suppress
R6906 T13676 T13673 prep by,suppress
R6907 T13677 T13676 pcomp inhibiting,by
R6908 T13678 T13680 compound CD28,phosphorylation
R6909 T13679 T13680 compound tyrosine,phosphorylation
R6910 T13680 T13677 dobj phosphorylation,inhibiting
R6911 T13681 T13680 cc and,phosphorylation
R6912 T13682 T13677 advcl binding,inhibiting
R6913 T13683 T13682 prep of,binding
R6914 T13684 T13686 nmod phosphatidylinositol,[
R6915 T13685 T13686 nmod 3-kinase,[
R6916 T13686 T13688 nmod [,]
R6917 T13687 T13688 nummod 24,]
R6918 T13688 T13683 pobj ],of
R6919 T13689 T13673 punct .,suppress
R6920 T13690 T13691 aux To,evaluate
R6921 T13691 T13703 advcl evaluate,purified
R6922 T13692 T13693 det the,responsiveness
R6923 T13693 T13691 dobj responsiveness,evaluate
R6924 T13694 T13693 prep of,responsiveness
R6925 T13695 T13696 compound RA,CD4
R6926 T13696 T13694 pobj CD4,of
R6927 T13697 T13699 amod +,cells
R6928 T13698 T13699 compound T,cells
R6929 T13699 T13691 dobj cells,evaluate
R6930 T13700 T13691 prep to,evaluate
R6931 T13701 T13700 pobj IL-10,to
R6932 T13702 T13703 punct ",",purified
R6933 T13703 T13703 ROOT purified,purified
R6934 T13704 T13705 compound PB,CD4
R6935 T13705 T13703 dobj CD4,purified
R6936 T13706 T13721 csubjpass +,stimulated
R6937 T13707 T13708 compound T,cells
R6938 T13708 T13706 dobj cells,+
R6939 T13709 T13706 prep from,+
R6940 T13710 T13711 nummod three,patients
R6941 T13711 T13709 pobj patients,from
R6942 T13712 T13711 prep with,patients
R6943 T13713 T13714 amod active,RA
R6944 T13714 T13712 pobj RA,with
R6945 T13715 T13712 cc and,with
R6946 T13716 T13706 prep from,+
R6947 T13717 T13719 nummod three,controls
R6948 T13718 T13719 amod healthy,controls
R6949 T13719 T13716 pobj controls,from
R6950 T13720 T13721 auxpass were,stimulated
R6951 T13721 T13703 ccomp stimulated,purified
R6952 T13722 T13721 agent by,stimulated
R6953 T13723 T13725 amod immobilized,antibody
R6954 T13724 T13725 amod anti-CD3,antibody
R6955 T13725 T13722 pobj antibody,by
R6956 T13726 T13725 cc and,antibody
R6957 T13727 T13728 compound anti-CD28,antibody
R6958 T13728 T13725 conj antibody,antibody
R6959 T13729 T13725 prep with,antibody
R6960 T13730 T13729 cc or,with
R6961 T13731 T13729 conj without,with
R6962 T13732 T13733 amod diluted,concentrations
R6963 T13733 T13731 pobj concentrations,without
R6964 T13734 T13733 prep of,concentrations
R6965 T13735 T13734 pobj IL-10,of
R6966 T13736 T13733 prep for,concentrations
R6967 T13737 T13738 nummod 36,hours
R6968 T13738 T13736 pobj hours,for
R6969 T13739 T13731 punct ",",without
R6970 T13740 T13731 cc and,without
R6971 T13741 T13742 compound IFN-γ,production
R6972 T13742 T13744 nsubjpass production,measured
R6973 T13743 T13744 auxpass was,measured
R6974 T13744 T13703 conj measured,purified
R6975 T13745 T13744 agent by,measured
R6976 T13746 T13745 pobj ELISA,by
R6977 T13747 T13744 punct .,measured
R6978 T13748 T13749 mark As,shown
R6979 T13749 T13765 advcl shown,inhibited
R6980 T13750 T13749 prep in,shown
R6981 T13751 T13750 pobj Fig.,in
R6982 T13752 T13751 nummod 1,Fig.
R6983 T13753 T13751 punct ",",Fig.
R6984 T13754 T13755 compound IFN-γ,production
R6985 T13755 T13765 nsubjpass production,inhibited
R6986 T13756 T13755 prep by,production
R6987 T13757 T13762 amod activated,cells
R6988 T13758 T13762 amod normal,cells
R6989 T13759 T13762 compound CD4,cells
R6990 T13760 T13762 nummod +,cells
R6991 T13761 T13762 compound T,cells
R6992 T13762 T13756 pobj cells,by
R6993 T13763 T13765 auxpass was,inhibited
R6994 T13764 T13765 advmod mostly,inhibited
R6995 T13765 T13765 ROOT inhibited,inhibited
R6996 T13766 T13765 prep at,inhibited
R6997 T13767 T13766 pobj concentrations,at
R6998 T13768 T13769 advmod as,low
R6999 T13769 T13767 amod low,concentrations
R7000 T13770 T13769 prep as,low
R7001 T13771 T13772 nummod 1,ng/ml
R7002 T13772 T13773 compound ng/ml,IL-10
R7003 T13773 T13770 pobj IL-10,as
R7004 T13774 T13765 punct .,inhibited
R7005 T13775 T13782 advmod However,were
R7006 T13776 T13782 punct ",",were
R7007 T13777 T13778 compound RA,CD4
R7008 T13778 T13781 compound CD4,cells
R7009 T13779 T13781 amod +,cells
R7010 T13780 T13781 compound T,cells
R7011 T13781 T13782 nsubj cells,were
R7012 T13782 T13782 ROOT were,were
R7013 T13783 T13782 acomp able,were
R7014 T13784 T13785 aux to,produce
R7015 T13785 T13783 xcomp produce,able
R7016 T13786 T13787 amod significant,amounts
R7017 T13787 T13785 dobj amounts,produce
R7018 T13788 T13787 prep of,amounts
R7019 T13789 T13788 pobj IFN-γ,of
R7020 T13790 T13785 prep in,produce
R7021 T13791 T13792 det the,presence
R7022 T13792 T13790 pobj presence,in
R7023 T13793 T13792 prep of,presence
R7024 T13794 T13796 nummod 1,IL-10
R7025 T13795 T13796 compound ng/ml,IL-10
R7026 T13796 T13793 pobj IL-10,of
R7027 T13797 T13782 punct ",",were
R7028 T13798 T13782 cc and,were
R7029 T13799 T13800 det the,maximal
R7030 T13800 T13808 nsubjpass maximal,obtained
R7031 T13801 T13800 cc but,maximal
R7032 T13802 T13803 neg not,complete
R7033 T13803 T13800 conj complete,maximal
R7034 T13804 T13803 dobj inhibition,complete
R7035 T13805 T13803 prep by,complete
R7036 T13806 T13805 pobj IL-10,by
R7037 T13807 T13808 auxpass was,obtained
R7038 T13808 T13782 conj obtained,were
R7039 T13809 T13808 prep at,obtained
R7040 T13810 T13809 pobj 10,at
R7041 T13811 T13812 nummod 100,ng/ml
R7042 T13812 T13810 appos ng/ml,10
R7043 T13813 T13808 punct .,obtained
R7044 T13814 T13816 nsubj We,compared
R7045 T13815 T13816 advmod thus,compared
R7046 T13816 T13816 ROOT compared,compared
R7047 T13817 T13818 det the,levels
R7048 T13818 T13816 dobj levels,compared
R7049 T13819 T13818 prep of,levels
R7050 T13820 T13821 compound IFN-γ,production
R7051 T13821 T13819 pobj production,of
R7052 T13822 T13821 prep by,production
R7053 T13823 T13826 compound CD4,cells
R7054 T13824 T13826 compound +,cells
R7055 T13825 T13826 compound T,cells
R7056 T13826 T13822 pobj cells,by
R7057 T13827 T13816 prep after,compared
R7058 T13828 T13831 nsubj CD3,costimulation
R7059 T13829 T13828 cc and,CD3
R7060 T13830 T13828 conj CD28,CD3
R7061 T13831 T13827 pobj costimulation,after
R7062 T13832 T13831 prep in,costimulation
R7063 T13833 T13834 det the,presence
R7064 T13834 T13832 pobj presence,in
R7065 T13835 T13834 prep of,presence
R7066 T13836 T13838 nummod 1,IL-10
R7067 T13837 T13838 compound ng/ml,IL-10
R7068 T13838 T13835 pobj IL-10,of
R7069 T13839 T13838 prep in,IL-10
R7070 T13840 T13841 compound RA,patients
R7071 T13841 T13839 pobj patients,in
R7072 T13842 T13841 prep with,patients
R7073 T13843 T13844 amod active,disease
R7074 T13844 T13842 pobj disease,with
R7075 T13845 T13844 punct (,disease
R7076 T13846 T13848 amod multiple,joints
R7077 T13847 T13848 amod inflammatory,joints
R7078 T13848 T13844 appos joints,disease
R7079 T13849 T13844 punct ",",disease
R7080 T13850 T13851 compound CRP,level
R7081 T13851 T13852 nsubj level,≥
R7082 T13852 T13831 npadvmod ≥,costimulation
R7083 T13853 T13854 nummod 10,mg/l
R7084 T13854 T13852 appos mg/l,≥
R7085 T13855 T13852 punct ),≥
R7086 T13856 T13852 cc and,≥
R7087 T13857 T13858 amod inactive,disease
R7088 T13858 T13852 conj disease,≥
R7089 T13859 T13852 punct (,≥
R7090 T13860 T13852 prep in,≥
R7091 T13861 T13860 pobj remission,in
R7092 T13862 T13852 punct ",",≥
R7093 T13863 T13864 compound CRP,level
R7094 T13864 T13852 conj level,≥
R7095 T13865 T13867 nmod <,mg/l
R7096 T13866 T13867 nummod 10,mg/l
R7097 T13867 T13864 appos mg/l,level
R7098 T13868 T13864 punct ),level
R7099 T13869 T13871 nmod [,]
R7100 T13870 T13871 nummod 26,]
R7101 T13871 T13864 nmod ],level
R7102 T13872 T13827 cc and,after
R7103 T13873 T13827 conj in,after
R7104 T13874 T13875 amod healthy,controls
R7105 T13875 T13873 pobj controls,in
R7106 T13876 T13816 punct .,compared
R7107 T13877 T13878 expl There,were
R7108 T13878 T13878 ROOT were,were
R7109 T13879 T13882 det no,differences
R7110 T13880 T13881 advmod statistically,significant
R7111 T13881 T13882 amod significant,differences
R7112 T13882 T13878 attr differences,were
R7113 T13883 T13882 prep in,differences
R7114 T13884 T13885 amod IFN-γ,production
R7115 T13885 T13883 pobj production,in
R7116 T13886 T13882 prep without,differences
R7117 T13887 T13886 pobj IL-10,without
R7118 T13888 T13887 prep among,IL-10
R7119 T13889 T13891 det these,groups
R7120 T13890 T13891 nummod three,groups
R7121 T13891 T13888 pobj groups,among
R7122 T13892 T13893 punct (,Fig.
R7123 T13893 T13878 attr Fig.,were
R7124 T13894 T13893 nummod 2a,Fig.
R7125 T13895 T13893 punct ),Fig.
R7126 T13896 T13878 punct ",",were
R7127 T13897 T13878 cc but,were
R7128 T13898 T13900 det the,effect
R7129 T13899 T13900 amod inhibitory,effect
R7130 T13900 T13908 nsubjpass effect,limited
R7131 T13901 T13900 prep of,effect
R7132 T13902 T13901 pobj IL-10,of
R7133 T13903 T13902 prep on,IL-10
R7134 T13904 T13905 compound IFN-γ,production
R7135 T13905 T13903 pobj production,on
R7136 T13906 T13908 auxpass was,limited
R7137 T13907 T13908 advmod significantly,limited
R7138 T13908 T13878 conj limited,were
R7139 T13909 T13908 prep in,limited
R7140 T13910 T13913 det the,group
R7141 T13911 T13913 amod active,group
R7142 T13912 T13913 compound RA,group
R7143 T13913 T13909 pobj group,in
R7144 T13914 T13908 prep as,limited
R7145 T13915 T13914 prep compared,as
R7146 T13916 T13915 prep with,compared
R7147 T13917 T13920 det the,group
R7148 T13918 T13920 amod inactive,group
R7149 T13919 T13920 compound RA,group
R7150 T13920 T13916 pobj group,with
R7151 T13921 T13920 cc and,group
R7152 T13922 T13923 amod healthy,controls
R7153 T13923 T13920 conj controls,group
R7154 T13924 T13926 punct (,decrease
R7155 T13925 T13926 compound percentage,decrease
R7156 T13926 T13920 appos decrease,group
R7157 T13927 T13926 punct :,decrease
R7158 T13928 T13929 amod active,RA
R7159 T13929 T13926 acl RA,decrease
R7160 T13930 T13929 punct ",",RA
R7161 T13931 T13933 quantmod 2.9,14.4
R7162 T13932 T13933 quantmod ±,14.4
R7163 T13933 T13934 nummod 14.4,%
R7164 T13934 T13929 appos %,RA
R7165 T13935 T13937 punct ;,RA
R7166 T13936 T13937 amod inactive,RA
R7167 T13937 T13929 conj RA,RA
R7168 T13938 T13937 punct ",",RA
R7169 T13939 T13941 quantmod 45.6,14.4
R7170 T13940 T13941 quantmod ±,14.4
R7171 T13941 T13942 nummod 14.4,%
R7172 T13942 T13937 appos %,RA
R7173 T13943 T13937 punct ;,RA
R7174 T13944 T13937 conj controls,RA
R7175 T13945 T13944 punct ",",controls
R7176 T13946 T13948 quantmod 65.8,7.9
R7177 T13947 T13948 quantmod ±,7.9
R7178 T13948 T13949 nummod 7.9,%
R7179 T13949 T13944 appos %,controls
R7180 T13950 T13944 punct ),controls
R7181 T13951 T13937 punct (,RA
R7182 T13952 T13937 npadvmod Fig.,RA
R7183 T13953 T13952 nummod 2b,Fig.
R7184 T13954 T13937 punct ),RA
R7185 T13955 T13908 punct .,limited
R7186 T13956 T13968 prep As,produced
R7187 T13957 T13958 det a,consequence
R7188 T13958 T13956 pobj consequence,As
R7189 T13959 T13968 punct ",",produced
R7190 T13960 T13963 compound CD4,cells
R7191 T13961 T13963 compound +,cells
R7192 T13962 T13963 compound T,cells
R7193 T13963 T13968 nsubj cells,produced
R7194 T13964 T13963 prep from,cells
R7195 T13965 T13967 amod active,patients
R7196 T13966 T13967 compound RA,patients
R7197 T13967 T13964 pobj patients,from
R7198 T13968 T13968 ROOT produced,produced
R7199 T13969 T13970 amod higher,levels
R7200 T13970 T13968 dobj levels,produced
R7201 T13971 T13970 prep of,levels
R7202 T13972 T13971 pobj IFN-γ,of
R7203 T13973 T13968 prep in,produced
R7204 T13974 T13975 det the,presence
R7205 T13975 T13973 pobj presence,in
R7206 T13976 T13975 prep of,presence
R7207 T13977 T13978 nummod 1,ng/ml
R7208 T13978 T13979 compound ng/ml,IL-10
R7209 T13979 T13976 pobj IL-10,of
R7210 T13980 T13981 mark than,did
R7211 T13981 T13968 advcl did,produced
R7212 T13982 T13986 amod normal,cells
R7213 T13983 T13986 nmod CD4,cells
R7214 T13984 T13986 nummod +,cells
R7215 T13985 T13986 compound T,cells
R7216 T13986 T13981 nsubj cells,did
R7217 T13987 T13981 punct (,did
R7218 T13988 T13981 nsubj Fig.,did
R7219 T13989 T13988 nummod 2a,Fig.
R7220 T13990 T13988 punct ),Fig.
R7221 T13991 T13968 punct .,produced
R7222 T13992 T13996 prep In,compared
R7223 T13993 T13992 pobj addition,In
R7224 T13994 T13996 punct ",",compared
R7225 T13995 T13996 nsubj we,compared
R7226 T13996 T13996 ROOT compared,compared
R7227 T13997 T13998 compound IL-2,production
R7228 T13998 T13996 dobj production,compared
R7229 T13999 T13998 prep by,production
R7230 T14000 T14003 compound CD4,cells
R7231 T14001 T14003 compound +,cells
R7232 T14002 T14003 compound T,cells
R7233 T14003 T13999 pobj cells,by
R7234 T14004 T13996 prep after,compared
R7235 T14005 T14008 nsubj CD3,costimulation
R7236 T14006 T14005 cc and,CD3
R7237 T14007 T14005 conj CD28,CD3
R7238 T14008 T14004 pobj costimulation,after
R7239 T14009 T14008 prep in,costimulation
R7240 T14010 T14011 det the,presence
R7241 T14011 T14009 pobj presence,in
R7242 T14012 T14011 prep of,presence
R7243 T14013 T14012 pobj IL-10,of
R7244 T14014 T14013 prep in,IL-10
R7245 T14015 T14017 amod active,patients
R7246 T14016 T14017 compound RA,patients
R7247 T14017 T14014 pobj patients,in
R7248 T14018 T14014 cc and,in
R7249 T14019 T14014 conj in,in
R7250 T14020 T14021 amod healthy,controls
R7251 T14021 T14019 pobj controls,in
R7252 T14022 T13996 punct .,compared
R7253 T14023 T14029 advmod Similarly,affected
R7254 T14024 T14029 punct ",",affected
R7255 T14025 T14026 compound IL-2,production
R7256 T14026 T14029 nsubjpass production,affected
R7257 T14027 T14029 auxpass was,affected
R7258 T14028 T14029 neg not,affected
R7259 T14029 T14029 ROOT affected,affected
R7260 T14030 T14029 agent by,affected
R7261 T14031 T14033 nummod 1,IL-10
R7262 T14032 T14033 compound ng/ml,IL-10
R7263 T14033 T14030 pobj IL-10,by
R7264 T14034 T14033 prep in,IL-10
R7265 T14035 T14036 compound RA,patients
R7266 T14036 T14034 pobj patients,in
R7267 T14037 T14039 punct (,decrease
R7268 T14038 T14039 compound percentage,decrease
R7269 T14039 T14033 appos decrease,IL-10
R7270 T14040 T14039 punct ",",decrease
R7271 T14041 T14042 nummod -2.1,±
R7272 T14042 T14039 appos ±,decrease
R7273 T14043 T14044 nummod 13.8,%
R7274 T14044 T14042 appos %,±
R7275 T14045 T14042 punct ),±
R7276 T14046 T14029 punct ",",affected
R7277 T14047 T14051 mark while,reduced
R7278 T14048 T14051 nsubjpass it,reduced
R7279 T14049 T14051 auxpass was,reduced
R7280 T14050 T14051 advmod significantly,reduced
R7281 T14051 T14029 advcl reduced,affected
R7282 T14052 T14051 prep in,reduced
R7283 T14053 T14054 amod healthy,controls
R7284 T14054 T14052 pobj controls,in
R7285 T14055 T14057 punct (,±
R7286 T14056 T14057 nummod 61.1,±
R7287 T14057 T14029 dep ±,affected
R7288 T14058 T14059 nummod 13.7,%
R7289 T14059 T14057 appos %,±
R7290 T14060 T14062 punct ;,<
R7291 T14061 T14062 compound P,<
R7292 T14062 T14057 appos <,±
R7293 T14063 T14062 nummod 0.05,<
R7294 T14064 T14062 punct ),<
R7295 T14065 T14029 punct .,affected
R7296 T14066 T14071 advcl Taken,indicate
R7297 T14067 T14066 advmod together,Taken
R7298 T14068 T14071 punct ",",indicate
R7299 T14069 T14070 det these,results
R7300 T14070 T14071 nsubj results,indicate
R7301 T14071 T14071 ROOT indicate,indicate
R7302 T14072 T14078 mark that,become
R7303 T14073 T14074 compound RA,CD4
R7304 T14074 T14078 nsubj CD4,become
R7305 T14075 T14077 amod +,cells
R7306 T14076 T14077 compound T,cells
R7307 T14077 T14078 nsubj cells,become
R7308 T14078 T14071 ccomp become,indicate
R7309 T14079 T14080 advmod less,susceptible
R7310 T14080 T14078 acomp susceptible,become
R7311 T14081 T14080 prep to,susceptible
R7312 T14082 T14084 det the,effect
R7313 T14083 T14084 amod immunoregulatory,effect
R7314 T14084 T14081 pobj effect,to
R7315 T14085 T14084 prep of,effect
R7316 T14086 T14085 pobj IL-10,of
R7317 T14087 T14084 prep during,effect
R7318 T14088 T14090 det the,phase
R7319 T14089 T14090 amod active,phase
R7320 T14090 T14087 pobj phase,during
R7321 T14091 T14071 punct .,indicate
R7612 T15039 T15040 amod Increased,expression
R7613 T15040 T15040 ROOT expression,expression
R7614 T15041 T15040 prep of,expression
R7615 T15042 T15043 compound cell,surface
R7616 T15043 T15044 compound surface,IL-10R1
R7617 T15044 T15041 pobj IL-10R1,of
R7618 T15045 T15040 prep on,expression
R7619 T15046 T15047 compound RA,CD4
R7620 T15047 T15045 pobj CD4,on
R7621 T15048 T15050 amod +,cells
R7622 T15049 T15050 compound T,cells
R7623 T15050 T15040 conj cells,expression
R7624 T15051 T15054 det The,complex
R7625 T15052 T15054 amod functional,complex
R7626 T15053 T15054 compound receptor,complex
R7627 T15054 T15057 nsubj complex,consists
R7628 T15055 T15054 prep of,complex
R7629 T15056 T15055 pobj IL-10,of
R7630 T15057 T15057 ROOT consists,consists
R7631 T15058 T15057 prep of,consists
R7632 T15059 T15060 nummod two,subunits
R7633 T15060 T15058 pobj subunits,of
R7634 T15061 T15060 punct ",",subunits
R7635 T15062 T15065 det the,component
R7636 T15063 T15065 amod primary,component
R7637 T15064 T15065 amod ligand-binding,component
R7638 T15065 T15066 compound component,IL-10R1
R7639 T15066 T15060 appos IL-10R1,subunits
R7640 T15067 T15066 cc and,IL-10R1
R7641 T15068 T15070 det the,component
R7642 T15069 T15070 compound accessory,component
R7643 T15070 T15071 compound component,type
R7644 T15071 T15066 conj type,IL-10R1
R7645 T15072 T15076 nummod 2,]
R7646 T15073 T15074 compound IL-10R,[
R7647 T15074 T15076 nmod [,]
R7648 T15075 T15076 nummod 1,]
R7649 T15076 T15066 conj ],IL-10R1
R7650 T15077 T15057 punct .,consists
R7651 T15078 T15079 nummod IL-10R1,expression
R7652 T15079 T15080 nsubj expression,plays
R7653 T15080 T15080 ROOT plays,plays
R7654 T15081 T15083 det a,role
R7655 T15082 T15083 amod critical,role
R7656 T15083 T15080 dobj role,plays
R7657 T15084 T15083 prep in,role
R7658 T15085 T15086 amod cellular,responses
R7659 T15086 T15084 pobj responses,in
R7660 T15087 T15086 prep to,responses
R7661 T15088 T15089 compound IL-10,[
R7662 T15089 T15087 pobj [,to
R7663 T15090 T15091 nummod 29,]
R7664 T15091 T15089 dobj ],[
R7665 T15092 T15080 punct .,plays
R7666 T15093 T15094 aux To,examine
R7667 T15094 T15107 advcl examine,was
R7668 T15095 T15104 mark whether,+
R7669 T15096 T15097 det the,resistance
R7670 T15097 T15104 nsubj resistance,+
R7671 T15098 T15097 prep to,resistance
R7672 T15099 T15100 compound IL-10,inhibition
R7673 T15100 T15098 pobj inhibition,to
R7674 T15101 T15100 prep in,inhibition
R7675 T15102 T15103 compound RA,CD4
R7676 T15103 T15101 pobj CD4,in
R7677 T15104 T15106 amod +,cells
R7678 T15105 T15106 compound T,cells
R7679 T15106 T15094 dobj cells,examine
R7680 T15107 T15107 ROOT was,was
R7681 T15108 T15107 acomp due,was
R7682 T15109 T15135 prep to,determined
R7683 T15110 T15112 amod limited,expression
R7684 T15111 T15112 compound receptor,expression
R7685 T15112 T15109 pobj expression,to
R7686 T15113 T15112 punct ",",expression
R7687 T15114 T15117 det the,expression
R7688 T15115 T15116 compound cell,surface
R7689 T15116 T15117 compound surface,expression
R7690 T15117 T15112 appos expression,expression
R7691 T15118 T15117 prep of,expression
R7692 T15119 T15118 pobj IL-10R1,of
R7693 T15120 T15117 prep on,expression
R7694 T15121 T15122 compound PB,CD4
R7695 T15122 T15120 pobj CD4,on
R7696 T15123 T15125 amod +,cells
R7697 T15124 T15125 compound T,cells
R7698 T15125 T15135 nsubjpass cells,determined
R7699 T15126 T15125 prep from,cells
R7700 T15127 T15129 amod active,patients
R7701 T15128 T15129 compound RA,patients
R7702 T15129 T15126 pobj patients,from
R7703 T15130 T15126 cc and,from
R7704 T15131 T15126 conj from,from
R7705 T15132 T15133 amod healthy,controls
R7706 T15133 T15131 pobj controls,from
R7707 T15134 T15135 auxpass was,determined
R7708 T15135 T15108 xcomp determined,due
R7709 T15136 T15135 agent by,determined
R7710 T15137 T15136 pobj flow,by
R7711 T15138 T15139 amod cytometric,analysis
R7712 T15139 T15135 npadvmod analysis,determined
R7713 T15140 T15107 punct .,was
R7714 T15141 T15142 mark As,shown
R7715 T15142 T15161 advcl shown,increased
R7716 T15143 T15142 prep in,shown
R7717 T15144 T15143 pobj Fig.,in
R7718 T15145 T15144 nummod 3a,Fig.
R7719 T15146 T15147 nummod ",3",b
R7720 T15147 T15161 npadvmod b,increased
R7721 T15148 T15161 punct ",",increased
R7722 T15149 T15150 det the,intensity
R7723 T15150 T15161 nsubjpass intensity,increased
R7724 T15151 T15150 prep of,intensity
R7725 T15152 T15153 amod IL-10R1,expression
R7726 T15153 T15151 pobj expression,of
R7727 T15154 T15150 prep on,intensity
R7728 T15155 T15158 compound CD4,cells
R7729 T15156 T15158 compound +,cells
R7730 T15157 T15158 compound T,cells
R7731 T15158 T15154 pobj cells,on
R7732 T15159 T15161 auxpass was,increased
R7733 T15160 T15161 advmod significantly,increased
R7734 T15161 T15161 ROOT increased,increased
R7735 T15162 T15161 prep in,increased
R7736 T15163 T15164 compound RA,patients
R7737 T15164 T15162 pobj patients,in
R7738 T15165 T15161 prep compared,increased
R7739 T15166 T15165 prep with,compared
R7740 T15167 T15166 prep in,with
R7741 T15168 T15169 amod healthy,controls
R7742 T15169 T15167 pobj controls,in
R7743 T15170 T15161 punct .,increased
R7744 T15171 T15172 det These,results
R7745 T15172 T15173 nsubj results,suggest
R7746 T15173 T15173 ROOT suggest,suggest
R7747 T15174 T15184 mark that,impaired
R7748 T15175 T15179 det the,pathway
R7749 T15176 T15179 amod intracellular,pathway
R7750 T15177 T15179 nmod signal,pathway
R7751 T15178 T15179 compound transduction,pathway
R7752 T15179 T15184 nsubjpass pathway,impaired
R7753 T15180 T15179 prep of,pathway
R7754 T15181 T15180 pobj IL-10,of
R7755 T15182 T15184 aux may,impaired
R7756 T15183 T15184 auxpass be,impaired
R7757 T15184 T15173 ccomp impaired,suggest
R7758 T15185 T15184 prep in,impaired
R7759 T15186 T15189 nummod CD4,cells
R7760 T15187 T15189 nummod +,cells
R7761 T15188 T15189 compound T,cells
R7762 T15189 T15185 pobj cells,in
R7763 T15190 T15189 prep of,cells
R7764 T15191 T15192 amod active,RA
R7765 T15192 T15190 pobj RA,of
R7766 T15193 T15173 punct .,suggest
R8282 T16494 T16497 amod Defective,phosphorylation
R8283 T16495 T16497 amod IL-10-mediated,phosphorylation
R8284 T16496 T16497 nummod STAT3,phosphorylation
R8285 T16497 T16501 nsubj phosphorylation,+
R8286 T16498 T16497 prep in,phosphorylation
R8287 T16499 T16500 compound RA,CD4
R8288 T16500 T16498 pobj CD4,in
R8289 T16501 T16501 ROOT +,+
R8290 T16502 T16503 compound T,cells
R8291 T16503 T16501 dobj cells,+
R8292 T16504 T16505 det The,interaction
R8293 T16505 T16510 nsubj interaction,induces
R8294 T16506 T16505 prep of,interaction
R8295 T16507 T16506 pobj IL-10R,of
R8296 T16508 T16505 prep with,interaction
R8297 T16509 T16508 pobj IL-10,with
R8298 T16510 T16501 dep induces,+
R8299 T16511 T16512 compound tyrosine,phosphorylation
R8300 T16512 T16510 dobj phosphorylation,induces
R8301 T16513 T16512 cc and,phosphorylation
R8302 T16514 T16512 conj activation,phosphorylation
R8303 T16515 T16512 prep of,phosphorylation
R8304 T16516 T16519 det the,factors
R8305 T16517 T16519 amod latent,factors
R8306 T16518 T16519 compound transcription,factors
R8307 T16519 T16515 pobj factors,of
R8308 T16520 T16525 nmod STAT1,]
R8309 T16521 T16520 cc and,STAT1
R8310 T16522 T16523 compound STAT3,[
R8311 T16523 T16520 conj [,STAT1
R8312 T16524 T16525 nummod 3,]
R8313 T16525 T16512 appos ],phosphorylation
R8314 T16526 T16510 punct .,induces
R8315 T16527 T16529 amod Macrophage-specific,mice
R8316 T16528 T16529 amod STAT3-deficient,mice
R8317 T16529 T16530 nsubj mice,demonstrated
R8318 T16530 T16530 ROOT demonstrated,demonstrated
R8319 T16531 T16533 mark that,plays
R8320 T16532 T16533 nsubj STAT3,plays
R8321 T16533 T16530 ccomp plays,demonstrated
R8322 T16534 T16536 det a,role
R8323 T16535 T16536 amod dominant,role
R8324 T16536 T16533 dobj role,plays
R8325 T16537 T16536 prep in,role
R8326 T16538 T16540 amod IL-10-mediated,responses
R8327 T16539 T16540 amod anti-inflammatory,responses
R8328 T16540 T16537 pobj responses,in
R8329 T16541 T16543 nmod [,]
R8330 T16542 T16543 nummod 5,]
R8331 T16543 T16533 npadvmod ],plays
R8332 T16544 T16543 punct ",",]
R8333 T16545 T16549 nsubj which,confirmed
R8334 T16546 T16549 aux has,confirmed
R8335 T16547 T16549 advmod recently,confirmed
R8336 T16548 T16549 auxpass been,confirmed
R8337 T16549 T16543 relcl confirmed,]
R8338 T16550 T16549 prep in,confirmed
R8339 T16551 T16552 amod human,macrophages
R8340 T16552 T16550 pobj macrophages,in
R8341 T16553 T16549 agent by,confirmed
R8342 T16554 T16553 pobj studies,by
R8343 T16555 T16554 prep of,studies
R8344 T16556 T16557 amod dominant-negative,STAT3
R8345 T16557 T16555 pobj STAT3,of
R8346 T16558 T16559 compound overexpression,[
R8347 T16559 T16561 nmod [,]
R8348 T16560 T16559 nummod 30,[
R8349 T16561 T16561 ROOT ],]
R8350 T16562 T16530 punct .,demonstrated
R8351 T16563 T16564 det The,induction
R8352 T16564 T16587 nsubjpass induction,examined
R8353 T16565 T16564 prep of,induction
R8354 T16566 T16565 pobj STAT1,of
R8355 T16567 T16566 cc and,STAT1
R8356 T16568 T16569 nummod STAT3,phosphorylation
R8357 T16569 T16566 conj phosphorylation,STAT1
R8358 T16570 T16569 agent by,phosphorylation
R8359 T16571 T16570 pobj IL-10,by
R8360 T16572 T16569 prep in,phosphorylation
R8361 T16573 T16574 compound PB,CD4
R8362 T16574 T16572 pobj CD4,in
R8363 T16575 T16587 nsubjpass +,examined
R8364 T16576 T16577 compound T,cells
R8365 T16577 T16575 dobj cells,+
R8366 T16578 T16577 prep from,cells
R8367 T16579 T16581 amod active,patients
R8368 T16580 T16581 compound RA,patients
R8369 T16581 T16578 pobj patients,from
R8370 T16582 T16578 cc and,from
R8371 T16583 T16578 conj from,from
R8372 T16584 T16585 amod healthy,controls
R8373 T16585 T16583 pobj controls,from
R8374 T16586 T16587 auxpass was,examined
R8375 T16587 T16587 ROOT examined,examined
R8376 T16588 T16587 advcl using,examined
R8377 T16589 T16590 amod western,blotting
R8378 T16590 T16588 dobj blotting,using
R8379 T16591 T16587 punct .,examined
R8380 T16592 T16593 nummod STAT3,phosphorylation
R8381 T16593 T16596 nsubjpass phosphorylation,induced
R8382 T16594 T16596 auxpass was,induced
R8383 T16595 T16596 advmod dose-dependently,induced
R8384 T16596 T16596 ROOT induced,induced
R8385 T16597 T16596 prep after,induced
R8386 T16598 T16599 compound IL-10,activation
R8387 T16599 T16597 pobj activation,after
R8388 T16600 T16596 prep for,induced
R8389 T16601 T16602 nummod 20,min
R8390 T16602 T16600 pobj min,for
R8391 T16603 T16602 prep in,min
R8392 T16604 T16608 amod normal,cells
R8393 T16605 T16608 nmod CD4,cells
R8394 T16606 T16608 nummod +,cells
R8395 T16607 T16608 compound T,cells
R8396 T16608 T16603 pobj cells,in
R8397 T16609 T16602 punct (,min
R8398 T16610 T16613 nmod Fig.,b
R8399 T16611 T16610 nummod 4a,Fig.
R8400 T16612 T16610 nummod ",4",Fig.
R8401 T16613 T16602 appos b,min
R8402 T16614 T16602 punct ),min
R8403 T16615 T16596 punct .,induced
R8404 T16616 T16621 prep In,phosphorylated
R8405 T16617 T16616 pobj contrast,In
R8406 T16618 T16621 punct ",",phosphorylated
R8407 T16619 T16621 nsubjpass STAT3,phosphorylated
R8408 T16620 T16621 auxpass was,phosphorylated
R8409 T16621 T16621 ROOT phosphorylated,phosphorylated
R8410 T16622 T16621 prep in,phosphorylated
R8411 T16623 T16624 advmod freshly,isolated
R8412 T16624 T16626 amod isolated,CD4
R8413 T16625 T16626 compound PB,CD4
R8414 T16626 T16622 pobj CD4,in
R8415 T16627 T16628 amod +,cells
R8416 T16628 T16636 nsubj cells,was
R8417 T16629 T16628 prep from,cells
R8418 T16630 T16631 compound RA,patients
R8419 T16631 T16629 pobj patients,from
R8420 T16632 T16628 cc and,cells
R8421 T16633 T16635 det this,phosphorylation
R8422 T16634 T16635 nummod STAT3,phosphorylation
R8423 T16635 T16628 conj phosphorylation,cells
R8424 T16636 T16621 ccomp was,phosphorylated
R8425 T16637 T16636 acomp detectable,was
R8426 T16638 T16636 prep for,was
R8427 T16639 T16641 quantmod up,6
R8428 T16640 T16641 quantmod to,6
R8429 T16641 T16642 nummod 6,hours
R8430 T16642 T16638 pobj hours,for
R8431 T16643 T16636 punct .,was
R8432 T16644 T16645 nummod STAT3,phosphorylation
R8433 T16645 T16647 nsubjpass phosphorylation,augmented
R8434 T16646 T16647 auxpass was,augmented
R8435 T16647 T16647 ROOT augmented,augmented
R8436 T16648 T16649 advmod only,when
R8437 T16649 T16650 advmod when,activated
R8438 T16650 T16647 advcl activated,augmented
R8439 T16651 T16650 agent by,activated
R8440 T16652 T16655 advmod as,10
R8441 T16653 T16655 amod much,10
R8442 T16654 T16655 quantmod as,10
R8443 T16655 T16657 nummod 10,IL-10
R8444 T16656 T16657 compound ng/ml,IL-10
R8445 T16657 T16651 pobj IL-10,by
R8446 T16658 T16647 punct .,augmented
R8447 T16659 T16662 preconj Both,phosphorylation
R8448 T16660 T16662 amod sustained,phosphorylation
R8449 T16661 T16662 nummod STAT3,phosphorylation
R8450 T16662 T16669 nsubjpass phosphorylation,found
R8451 T16663 T16662 cc and,phosphorylation
R8452 T16664 T16667 amod defective,phosphorylation
R8453 T16665 T16667 amod IL-10-induced,phosphorylation
R8454 T16666 T16667 nummod STAT3,phosphorylation
R8455 T16667 T16662 conj phosphorylation,phosphorylation
R8456 T16668 T16669 auxpass were,found
R8457 T16669 T16669 ROOT found,found
R8458 T16670 T16669 prep in,found
R8459 T16671 T16672 compound RA,ST
R8460 T16672 T16673 compound ST,CD4
R8461 T16673 T16670 pobj CD4,in
R8462 T16674 T16676 amod +,cells
R8463 T16675 T16676 compound T,cells
R8464 T16676 T16669 advcl cells,found
R8465 T16677 T16678 punct (,Fig.
R8466 T16678 T16676 appos Fig.,cells
R8467 T16679 T16678 nummod 4c,Fig.
R8468 T16680 T16676 punct ),cells
R8469 T16681 T16669 punct .,found
R8470 T16682 T16692 prep On,detected
R8471 T16683 T16685 det the,hand
R8472 T16684 T16685 amod other,hand
R8473 T16685 T16682 pobj hand,On
R8474 T16686 T16692 punct ",",detected
R8475 T16687 T16689 amod IL-10-induced,phosphorylation
R8476 T16688 T16689 nummod STAT1,phosphorylation
R8477 T16689 T16692 nsubjpass phosphorylation,detected
R8478 T16690 T16692 auxpass was,detected
R8479 T16691 T16692 neg not,detected
R8480 T16692 T16692 ROOT detected,detected
R8481 T16693 T16692 prep in,detected
R8482 T16694 T16696 det either,CD4
R8483 T16695 T16696 compound RA,CD4
R8484 T16696 T16693 pobj CD4,in
R8485 T16697 T16699 amod +,cells
R8486 T16698 T16699 compound T,cells
R8487 T16699 T16692 dobj cells,detected
R8488 T16700 T16699 cc or,cells
R8489 T16701 T16705 amod normal,cells
R8490 T16702 T16705 nmod CD4,cells
R8491 T16703 T16705 nummod +,cells
R8492 T16704 T16705 compound T,cells
R8493 T16705 T16699 conj cells,cells
R8494 T16706 T16692 punct (,detected
R8495 T16707 T16692 npadvmod Fig.,detected
R8496 T16708 T16707 nummod 4a,Fig.
R8497 T16709 T16707 punct ),Fig.
R8498 T16710 T16692 punct .,detected
R8499 T16711 T16712 det These,results
R8500 T16712 T16713 nsubj results,indicate
R8501 T16713 T16713 ROOT indicate,indicate
R8502 T16714 T16716 mark that,is
R8503 T16715 T16716 nsubj STAT3,is
R8504 T16716 T16713 ccomp is,indicate
R8505 T16717 T16720 det the,STAT
R8506 T16718 T16720 amod major,STAT
R8507 T16719 T16720 compound IL-10-activated,STAT
R8508 T16720 T16716 attr STAT,is
R8509 T16721 T16720 prep in,STAT
R8510 T16722 T16721 pobj CD4,in
R8511 T16723 T16725 compound +,cells
R8512 T16724 T16725 compound T,cells
R8513 T16725 T16733 nsubjpass cells,diminished
R8514 T16726 T16725 punct ",",cells
R8515 T16727 T16725 cc and,cells
R8516 T16728 T16730 amod IL-10-induced,activation
R8517 T16729 T16730 compound STAT3,activation
R8518 T16730 T16725 conj activation,cells
R8519 T16731 T16733 aux may,diminished
R8520 T16732 T16733 auxpass be,diminished
R8521 T16733 T16713 conj diminished,indicate
R8522 T16734 T16733 prep in,diminished
R8523 T16735 T16736 amod active,RA
R8524 T16736 T16734 pobj RA,in
R8525 T16737 T16733 punct ",",diminished
R8526 T16738 T16733 prep in,diminished
R8527 T16739 T16738 pobj association,in
R8528 T16740 T16733 prep with,diminished
R8529 T16741 T16743 amod sustained,phosphorylation
R8530 T16742 T16743 compound STAT3,phosphorylation
R8531 T16743 T16740 pobj phosphorylation,with
R8532 T16744 T16713 punct .,indicate
R9441 T19005 T19005 ROOT IL-6-mediated,IL-6-mediated
R9442 T19006 T19007 nummod STAT3,phosphorylation
R9443 T19007 T19021 nsubjpass phosphorylation,activated
R9444 T19008 T19007 cc and,phosphorylation
R9445 T19009 T19007 conj inhibition,phosphorylation
R9446 T19010 T19009 prep of,inhibition
R9447 T19011 T19012 amod IL-10,effect
R9448 T19012 T19010 pobj effect,of
R9449 T19013 T19007 prep in,phosphorylation
R9450 T19014 T19018 amod normal,cells
R9451 T19015 T19017 compound CD4,T
R9452 T19016 T19017 compound +,T
R9453 T19017 T19018 compound T,cells
R9454 T19018 T19013 pobj cells,in
R9455 T19019 T19021 nsubjpass STAT3,activated
R9456 T19020 T19021 auxpass is,activated
R9457 T19021 T19021 ROOT activated,activated
R9458 T19022 T19021 agent by,activated
R9459 T19023 T19024 amod many,cytokines
R9460 T19024 T19022 pobj cytokines,by
R9461 T19025 T19024 cc and,cytokines
R9462 T19026 T19027 compound growth,factors
R9463 T19027 T19024 conj factors,cytokines
R9464 T19028 T19029 amod such,as
R9465 T19029 T19027 prep as,factors
R9466 T19030 T19032 det the,family
R9467 T19031 T19032 compound IL-6,family
R9468 T19032 T19029 pobj family,as
R9469 T19033 T19032 prep of,family
R9470 T19034 T19033 pobj cytokines,of
R9471 T19035 T19042 punct (,factor
R9472 T19036 T19042 nmod IL-6,factor
R9473 T19037 T19036 punct ",",IL-6
R9474 T19038 T19036 conj IL-11,IL-6
R9475 T19039 T19038 punct ",",IL-11
R9476 T19040 T19042 nmod leukemia,factor
R9477 T19041 T19042 amod inhibitory,factor
R9478 T19042 T19032 appos factor,family
R9479 T19043 T19042 punct ",",factor
R9480 T19044 T19042 cc and,factor
R9481 T19045 T19046 compound oncostatin,M
R9482 T19046 T19042 conj M,factor
R9483 T19047 T19032 punct ),family
R9484 T19048 T19051 punct ",",factor
R9485 T19049 T19051 amod platelet-derived,factor
R9486 T19050 T19051 compound growth,factor
R9487 T19051 T19027 conj factor,factors
R9488 T19052 T19051 punct ",",factor
R9489 T19053 T19051 cc and,factor
R9490 T19054 T19056 amod epidermal,factor
R9491 T19055 T19056 compound growth,factor
R9492 T19056 T19051 conj factor,factor
R9493 T19057 T19051 punct ",",factor
R9494 T19058 T19070 prep in,demonstrated
R9495 T19059 T19058 pobj addition,in
R9496 T19060 T19059 prep to,addition
R9497 T19061 T19060 pobj IL-10,to
R9498 T19062 T19064 nmod [,]
R9499 T19063 T19064 nummod 4,]
R9500 T19064 T19061 dobj ],IL-10
R9501 T19065 T19061 punct ",",IL-10
R9502 T19066 T19070 cc but,demonstrated
R9503 T19067 T19068 amod previous,studies
R9504 T19068 T19070 nsubj studies,demonstrated
R9505 T19069 T19070 aux have,demonstrated
R9506 T19070 T19021 conj demonstrated,activated
R9507 T19071 T19073 mark that,is
R9508 T19072 T19073 nsubj IL-6,is
R9509 T19073 T19070 ccomp is,demonstrated
R9510 T19074 T19076 det the,factor
R9511 T19075 T19076 amod major,factor
R9512 T19076 T19073 attr factor,is
R9513 T19077 T19076 prep in,factor
R9514 T19078 T19080 nmod RA,fluid
R9515 T19079 T19080 amod synovial,fluid
R9516 T19080 T19076 appos fluid,factor
R9517 T19081 T19082 nsubj that,induces
R9518 T19082 T19080 relcl induces,fluid
R9519 T19083 T19084 amod constitutive,activation
R9520 T19084 T19082 dobj activation,induces
R9521 T19085 T19084 prep of,activation
R9522 T19086 T19085 pobj STAT3,of
R9523 T19087 T19084 prep in,activation
R9524 T19088 T19089 amod mononuclear,cells
R9525 T19089 T19087 pobj cells,in
R9526 T19090 T19092 nmod [,]
R9527 T19091 T19092 nummod 31,]
R9528 T19092 T19080 appos ],fluid
R9529 T19093 T19070 punct .,demonstrated
R9530 T19094 T19096 mark Since,is
R9531 T19095 T19096 nsubj IL-6,is
R9532 T19096 T19107 advcl is,detected
R9533 T19097 T19096 advmod also,is
R9534 T19098 T19096 acomp abundant,is
R9535 T19099 T19098 prep in,abundant
R9536 T19100 T19099 pobj sera,in
R9537 T19101 T19100 prep of,sera
R9538 T19102 T19104 amod active,patients
R9539 T19103 T19104 compound RA,patients
R9540 T19104 T19101 pobj patients,of
R9541 T19105 T19107 punct ",",detected
R9542 T19106 T19107 advmod frequently,detected
R9543 T19107 T19117 advcl detected,examined
R9544 T19108 T19107 prep at,detected
R9545 T19109 T19108 pobj >,at
R9546 T19110 T19114 nummod 1,]
R9547 T19111 T19112 amod ng/ml,[
R9548 T19112 T19114 nmod [,]
R9549 T19113 T19114 nummod 27,]
R9550 T19114 T19107 dobj ],detected
R9551 T19115 T19117 punct ",",examined
R9552 T19116 T19117 nsubj we,examined
R9553 T19117 T19117 ROOT examined,examined
R9554 T19118 T19135 mark whether,was
R9555 T19119 T19120 amod persistent,exposure
R9556 T19120 T19135 nsubj exposure,was
R9557 T19121 T19120 prep of,exposure
R9558 T19122 T19125 nummod CD4,cells
R9559 T19123 T19125 nummod +,cells
R9560 T19124 T19125 compound T,cells
R9561 T19125 T19121 pobj cells,of
R9562 T19126 T19120 prep to,exposure
R9563 T19127 T19128 amod high,concentrations
R9564 T19128 T19126 pobj concentrations,to
R9565 T19129 T19128 prep of,concentrations
R9566 T19130 T19129 pobj IL-6,of
R9567 T19131 T19128 prep in,concentrations
R9568 T19132 T19134 det the,circulation
R9569 T19133 T19134 compound blood,circulation
R9570 T19134 T19131 pobj circulation,in
R9571 T19135 T19117 ccomp was,examined
R9572 T19136 T19135 acomp responsible,was
R9573 T19137 T19136 prep for,responsible
R9574 T19138 T19141 poss their,activation
R9575 T19139 T19141 amod sustained,activation
R9576 T19140 T19141 nummod STAT3,activation
R9577 T19141 T19137 pobj activation,for
R9578 T19142 T19141 cc and,activation
R9579 T19143 T19141 conj resistance,activation
R9580 T19144 T19143 prep to,resistance
R9581 T19145 T19146 compound IL-10,inhibition
R9582 T19146 T19144 pobj inhibition,to
R9583 T19147 T19146 prep in,inhibition
R9584 T19148 T19149 amod active,RA
R9585 T19149 T19147 pobj RA,in
R9586 T19150 T19117 punct .,examined
R9587 T19151 T19152 det Both,STAT1
R9588 T19152 T19155 nummod STAT1,phosphorylation
R9589 T19153 T19152 cc and,STAT1
R9590 T19154 T19152 conj STAT3,STAT1
R9591 T19155 T19157 nsubjpass phosphorylation,activated
R9592 T19156 T19157 auxpass was,activated
R9593 T19157 T19157 ROOT activated,activated
R9594 T19158 T19157 agent by,activated
R9595 T19159 T19158 pobj IL-6,by
R9596 T19160 T19157 prep in,activated
R9597 T19161 T19165 amod normal,cells
R9598 T19162 T19165 nmod CD4,cells
R9599 T19163 T19165 nummod +,cells
R9600 T19164 T19165 compound T,cells
R9601 T19165 T19160 pobj cells,in
R9602 T19166 T19165 punct (,cells
R9603 T19167 T19177 nsubj data,[
R9604 T19168 T19169 neg not,shown
R9605 T19169 T19167 acl shown,data
R9606 T19170 T19167 punct ),data
R9607 T19171 T19177 punct ",",[
R9608 T19172 T19177 prep in,[
R9609 T19173 T19172 pobj agreement,in
R9610 T19174 T19173 prep with,agreement
R9611 T19175 T19176 amod previous,observations
R9612 T19176 T19174 pobj observations,with
R9613 T19177 T19157 advcl [,activated
R9614 T19178 T19179 nummod 4,]
R9615 T19179 T19177 dobj ],[
R9616 T19180 T19177 punct .,[
R9617 T19181 T19185 amod Normal,cells
R9618 T19182 T19185 compound CD4,cells
R9619 T19183 T19185 nummod +,cells
R9620 T19184 T19185 compound T,cells
R9621 T19185 T19188 nsubjpass cells,incubated
R9622 T19186 T19188 auxpass were,incubated
R9623 T19187 T19188 advmod thus,incubated
R9624 T19188 T19188 ROOT incubated,incubated
R9625 T19189 T19188 prep for,incubated
R9626 T19190 T19191 nummod 20,min
R9627 T19191 T19189 pobj min,for
R9628 T19192 T19191 prep with,min
R9629 T19193 T19194 compound culture,medium
R9630 T19194 T19195 nsubj medium,containing
R9631 T19195 T19192 pcomp containing,with
R9632 T19196 T19197 nummod 30,%
R9633 T19197 T19198 compound %,serum
R9634 T19198 T19195 dobj serum,containing
R9635 T19199 T19198 prep from,serum
R9636 T19200 T19202 amod active,patients
R9637 T19201 T19202 compound RA,patients
R9638 T19202 T19199 pobj patients,from
R9639 T19203 T19195 cc and,containing
R9640 T19204 T19195 conj neutralizing,containing
R9641 T19205 T19206 amod anti-IL-6,antibody
R9642 T19206 T19204 dobj antibody,neutralizing
R9643 T19207 T19206 cc or,antibody
R9644 T19208 T19209 compound control,antibody
R9645 T19209 T19206 conj antibody,antibody
R9646 T19210 T19204 punct ",",neutralizing
R9647 T19211 T19204 cc and,neutralizing
R9648 T19212 T19213 compound STAT,phosphorylation
R9649 T19213 T19215 nsubjpass phosphorylation,examined
R9650 T19214 T19215 auxpass was,examined
R9651 T19215 T19188 advcl examined,incubated
R9652 T19216 T19215 agent by,examined
R9653 T19217 T19219 amod western,analysis
R9654 T19218 T19219 compound blot,analysis
R9655 T19219 T19216 pobj analysis,by
R9656 T19220 T19215 punct .,examined
R9657 T19221 T19222 compound RA,serum
R9658 T19222 T19223 nsubj serum,was
R9659 T19223 T19223 ROOT was,was
R9660 T19224 T19223 acomp able,was
R9661 T19225 T19226 aux to,induce
R9662 T19226 T19224 xcomp induce,able
R9663 T19227 T19228 amod tyrosine,phosphorylation
R9664 T19228 T19226 dobj phosphorylation,induce
R9665 T19229 T19228 prep of,phosphorylation
R9666 T19230 T19229 pobj STAT3,of
R9667 T19231 T19230 cc but,STAT3
R9668 T19232 T19233 neg not,STAT1
R9669 T19233 T19241 nsubjpass STAT1,abolished
R9670 T19234 T19233 punct ",",STAT1
R9671 T19235 T19233 cc and,STAT1
R9672 T19236 T19238 det this,activation
R9673 T19237 T19238 nummod STAT3,activation
R9674 T19238 T19233 conj activation,STAT1
R9675 T19239 T19241 auxpass was,abolished
R9676 T19240 T19241 advmod mostly,abolished
R9677 T19241 T19223 advcl abolished,was
R9678 T19242 T19241 agent by,abolished
R9679 T19243 T19242 pobj neutralization,by
R9680 T19244 T19243 prep of,neutralization
R9681 T19245 T19246 compound IL-6,activity
R9682 T19246 T19244 pobj activity,of
R9683 T19247 T19241 punct (,abolished
R9684 T19248 T19249 compound Fig.,5a
R9685 T19249 T19241 npadvmod 5a,abolished
R9686 T19250 T19241 punct ),abolished
R9687 T19251 T19223 punct .,was
R9688 T19252 T19253 det These,results
R9689 T19253 T19254 nsubj results,indicate
R9690 T19254 T19254 ROOT indicate,indicate
R9691 T19255 T19257 mark that,is
R9692 T19256 T19257 nsubj IL-6,is
R9693 T19257 T19254 ccomp is,indicate
R9694 T19258 T19261 det the,factor
R9695 T19259 T19261 amod dominant,factor
R9696 T19260 T19261 amod STAT3-activating,factor
R9697 T19261 T19257 attr factor,is
R9698 T19262 T19261 acl contained,factor
R9699 T19263 T19262 prep in,contained
R9700 T19264 T19263 pobj sera,in
R9701 T19265 T19264 prep of,sera
R9702 T19266 T19268 amod active,patients
R9703 T19267 T19268 compound RA,patients
R9704 T19268 T19265 pobj patients,of
R9705 T19269 T19254 punct .,indicate
R9706 T19270 T19271 det The,lack
R9707 T19271 T19278 nsubj lack,suggests
R9708 T19272 T19271 prep of,lack
R9709 T19273 T19274 nummod STAT1,activation
R9710 T19274 T19272 pobj activation,of
R9711 T19275 T19274 prep by,activation
R9712 T19276 T19277 compound RA,serum
R9713 T19277 T19275 pobj serum,by
R9714 T19278 T19278 ROOT suggests,suggests
R9715 T19279 T19287 mark that,required
R9716 T19280 T19281 advmod much,higher
R9717 T19281 T19282 amod higher,concentrations
R9718 T19282 T19287 nsubjpass concentrations,required
R9719 T19283 T19282 prep of,concentrations
R9720 T19284 T19283 pobj IL-6,of
R9721 T19285 T19287 aux may,required
R9722 T19286 T19287 auxpass be,required
R9723 T19287 T19278 ccomp required,suggests
R9724 T19288 T19287 prep for,required
R9725 T19289 T19290 nummod STAT1,activation
R9726 T19290 T19288 pobj activation,for
R9727 T19291 T19290 prep as,activation
R9728 T19292 T19291 prep compared,as
R9729 T19293 T19292 prep with,compared
R9730 T19294 T19295 nummod STAT3,activation
R9731 T19295 T19293 pobj activation,with
R9732 T19296 T19295 punct ",",activation
R9733 T19297 T19295 cc or,activation
R9734 T19298 T19304 mark that,be
R9735 T19299 T19304 nsubj inhibitors,be
R9736 T19300 T19299 prep of,inhibitors
R9737 T19301 T19300 pobj STAT1,of
R9738 T19302 T19304 nsubj signaling,be
R9739 T19303 T19304 aux may,be
R9740 T19304 T19287 advcl be,required
R9741 T19305 T19304 acomp present,be
R9742 T19306 T19305 prep in,present
R9743 T19307 T19308 compound RA,serum
R9744 T19308 T19306 pobj serum,in
R9745 T19309 T19278 punct .,suggests
R9746 T19310 T19312 nsubj We,examined
R9747 T19311 T19312 advmod next,examined
R9748 T19312 T19312 ROOT examined,examined
R9749 T19313 T19316 mark whether,suppress
R9750 T19314 T19316 nsubj IL-6,suppress
R9751 T19315 T19316 aux could,suppress
R9752 T19316 T19312 ccomp suppress,examined
R9753 T19317 T19318 det the,effect
R9754 T19318 T19316 dobj effect,suppress
R9755 T19319 T19318 prep of,effect
R9756 T19320 T19319 pobj IL-10,of
R9757 T19321 T19322 aux to,inhibit
R9758 T19322 T19316 advcl inhibit,suppress
R9759 T19323 T19324 amod IFN-γ,production
R9760 T19324 T19322 dobj production,inhibit
R9761 T19325 T19324 prep by,production
R9762 T19326 T19329 compound CD4,cells
R9763 T19327 T19329 compound +,cells
R9764 T19328 T19329 compound T,cells
R9765 T19329 T19325 pobj cells,by
R9766 T19330 T19312 punct .,examined
R9767 T19331 T19349 prep After,stimulated
R9768 T19332 T19331 pobj preincubation,After
R9769 T19333 T19332 prep with,preincubation
R9770 T19334 T19333 cc or,with
R9771 T19335 T19333 conj without,with
R9772 T19336 T19337 nummod 10,ng/ml
R9773 T19337 T19338 compound ng/ml,IL-6
R9774 T19338 T19335 pobj IL-6,without
R9775 T19339 T19332 prep for,preincubation
R9776 T19340 T19341 nummod 36,hours
R9777 T19341 T19339 pobj hours,for
R9778 T19342 T19349 punct ",",stimulated
R9779 T19343 T19347 amod normal,cells
R9780 T19344 T19347 compound CD4,cells
R9781 T19345 T19347 nummod +,cells
R9782 T19346 T19347 compound T,cells
R9783 T19347 T19349 nsubjpass cells,stimulated
R9784 T19348 T19349 auxpass were,stimulated
R9785 T19349 T19349 ROOT stimulated,stimulated
R9786 T19350 T19349 agent by,stimulated
R9787 T19351 T19350 pobj CD3,by
R9788 T19352 T19351 cc and,CD3
R9789 T19353 T19354 compound CD28,costimulation
R9790 T19354 T19351 conj costimulation,CD3
R9791 T19355 T19354 prep in,costimulation
R9792 T19356 T19357 det the,presence
R9793 T19357 T19355 pobj presence,in
R9794 T19358 T19357 cc or,presence
R9795 T19359 T19357 conj absence,presence
R9796 T19360 T19357 prep of,presence
R9797 T19361 T19362 nummod 1,ng/ml
R9798 T19362 T19363 compound ng/ml,IL-10
R9799 T19363 T19360 pobj IL-10,of
R9800 T19364 T19354 prep for,costimulation
R9801 T19365 T19366 nummod 36,hours
R9802 T19366 T19364 pobj hours,for
R9803 T19367 T19354 punct ",",costimulation
R9804 T19368 T19354 cc and,costimulation
R9805 T19369 T19371 det the,production
R9806 T19370 T19371 compound IFN-γ,production
R9807 T19371 T19373 nsubjpass production,measured
R9808 T19372 T19373 auxpass was,measured
R9809 T19373 T19349 conj measured,stimulated
R9810 T19374 T19373 agent by,measured
R9811 T19375 T19374 pobj ELISA,by
R9812 T19376 T19373 punct .,measured
R9813 T19377 T19378 compound IL-6,pretreatment
R9814 T19378 T19382 nsubj pretreatment,reduced
R9815 T19379 T19378 prep of,pretreatment
R9816 T19380 T19381 amod normal,cells
R9817 T19381 T19379 pobj cells,of
R9818 T19382 T19382 ROOT reduced,reduced
R9819 T19383 T19384 amod IL-10-mediated,inhibition
R9820 T19384 T19382 dobj inhibition,reduced
R9821 T19385 T19384 prep of,inhibition
R9822 T19386 T19387 compound IFN-γ,production
R9823 T19387 T19385 pobj production,of
R9824 T19388 T19387 punct (,production
R9825 T19389 T19384 appos Fig.,inhibition
R9826 T19390 T19389 nummod 5b,Fig.
R9827 T19391 T19382 punct ),reduced
R9828 T19392 T19382 punct ",",reduced
R9829 T19393 T19382 advcl indicating,reduced
R9830 T19394 T19400 mark that,modulate
R9831 T19395 T19396 amod high,concentrations
R9832 T19396 T19400 nsubj concentrations,modulate
R9833 T19397 T19396 prep of,concentrations
R9834 T19398 T19397 pobj IL-6,of
R9835 T19399 T19400 aux could,modulate
R9836 T19400 T19393 ccomp modulate,indicating
R9837 T19401 T19402 compound T-cell,responsiveness
R9838 T19402 T19400 dobj responsiveness,modulate
R9839 T19403 T19402 prep to,responsiveness
R9840 T19404 T19403 pobj IL-10,to
R9841 T19405 T19382 punct .,reduced
R9842 T19406 T19411 advcl Taken,suggest
R9843 T19407 T19406 advmod together,Taken
R9844 T19408 T19411 punct ",",suggest
R9845 T19409 T19410 det these,findings
R9846 T19410 T19411 nsubj findings,suggest
R9847 T19411 T19411 ROOT suggest,suggest
R9848 T19412 T19419 mark that,have
R9849 T19413 T19414 amod persistent,exposure
R9850 T19414 T19419 nsubj exposure,have
R9851 T19415 T19416 aux to,serum
R9852 T19416 T19414 acl serum,exposure
R9853 T19417 T19416 dobj IL-6,serum
R9854 T19418 T19419 aux may,have
R9855 T19419 T19411 ccomp have,suggest
R9856 T19420 T19421 det a,role
R9857 T19421 T19419 dobj role,have
R9858 T19422 T19421 prep in,role
R9859 T19423 T19425 preconj both,induction
R9860 T19424 T19425 det the,induction
R9861 T19425 T19422 pobj induction,in
R9862 T19426 T19425 prep of,induction
R9863 T19427 T19428 nummod STAT3,activation
R9864 T19428 T19426 pobj activation,of
R9865 T19429 T19428 cc and,activation
R9866 T19430 T19431 det the,resistance
R9867 T19431 T19428 conj resistance,activation
R9868 T19432 T19431 prep to,resistance
R9869 T19433 T19435 det the,effect
R9870 T19434 T19435 amod inhibitory,effect
R9871 T19435 T19432 pobj effect,to
R9872 T19436 T19435 prep of,effect
R9873 T19437 T19436 pobj IL-10,of
R9874 T19438 T19435 prep in,effect
R9875 T19439 T19440 compound RA,CD4
R9876 T19440 T19438 pobj CD4,in
R9877 T19441 T19443 amod +,cells
R9878 T19442 T19443 compound T,cells
R9879 T19443 T19425 conj cells,induction
R9880 T19444 T19411 punct .,suggest
R10484 T20959 T20960 compound High,expression
R10485 T20960 T20971 nsubj expression,induces
R10486 T20961 T20960 prep of,expression
R10487 T20962 T20963 nummod SOCS1,mRNA
R10488 T20963 T20969 nmod mRNA,cells
R10489 T20964 T20963 prep in,mRNA
R10490 T20965 T20966 compound RA,CD4
R10491 T20966 T20964 pobj CD4,in
R10492 T20967 T20969 amod +,cells
R10493 T20968 T20969 compound T,cells
R10494 T20969 T20961 pobj cells,of
R10495 T20970 T20971 nsubj IL-6,induces
R10496 T20971 T20971 ROOT induces,induces
R10497 T20972 T20974 nummod two,inhibitors
R10498 T20973 T20974 amod potent,inhibitors
R10499 T20974 T20971 dobj inhibitors,induces
R10500 T20975 T20974 prep of,inhibitors
R10501 T20976 T20975 pobj JAKs,of
R10502 T20977 T20976 punct (,JAKs
R10503 T20978 T20981 nummod SOCS1,proteins
R10504 T20979 T20978 cc and,SOCS1
R10505 T20980 T20978 conj SOCS3,SOCS1
R10506 T20981 T20976 appos proteins,JAKs
R10507 T20982 T20976 punct ),JAKs
R10508 T20983 T20986 nsubj that,act
R10509 T20984 T20986 neg not,act
R10510 T20985 T20986 amod only,act
R10511 T20986 T20974 relcl act,inhibitors
R10512 T20987 T20986 prep as,act
R10513 T20988 T20987 pobj mediators,as
R10514 T20989 T20988 prep of,mediators
R10515 T20990 T20992 amod negative,inhibition
R10516 T20991 T20992 compound feedback,inhibition
R10517 T20992 T20989 pobj inhibition,of
R10518 T20993 T20986 punct ",",act
R10519 T20994 T20986 cc but,act
R10520 T20995 T20996 advmod also,play
R10521 T20996 T20986 conj play,act
R10522 T20997 T20999 det a,role
R10523 T20998 T20999 amod major,role
R10524 T20999 T20996 dobj role,play
R10525 T21000 T20996 prep in,play
R10526 T21001 T21002 compound crosstalk,inhibition
R10527 T21002 T21000 pobj inhibition,in
R10528 T21003 T20996 prep by,play
R10529 T21004 T21003 pcomp opposing,by
R10530 T21005 T21007 amod other,pathways
R10531 T21006 T21007 amod cytokine-signaling,pathways
R10532 T21007 T21004 dobj pathways,opposing
R10533 T21008 T20996 conj [,play
R10534 T21009 T21010 nummod 7,]
R10535 T21010 T21008 dobj ],[
R10536 T21011 T20971 punct .,induces
R10537 T21012 T21016 nsubj SOCS3,shown
R10538 T21013 T21016 aux has,shown
R10539 T21014 T21016 advmod recently,shown
R10540 T21015 T21016 auxpass been,shown
R10541 T21016 T21016 ROOT shown,shown
R10542 T21017 T21019 aux to,inhibit
R10543 T21018 T21019 advmod specifically,inhibit
R10544 T21019 T21016 advcl inhibit,shown
R10545 T21020 T21021 amod STAT3,activation
R10546 T21021 T21019 dobj activation,inhibit
R10547 T21022 T21021 acl induced,activation
R10548 T21023 T21022 agent by,induced
R10549 T21024 T21023 pobj IL-6,by
R10550 T21025 T21022 cc but,induced
R10551 T21026 T21027 neg not,by
R10552 T21027 T21022 conj by,induced
R10553 T21028 T21027 pobj IL-10,by
R10554 T21029 T21016 punct ",",shown
R10555 T21030 T21031 advmod thereby,regulating
R10556 T21031 T21016 advcl regulating,shown
R10557 T21032 T21034 det the,action
R10558 T21033 T21034 amod divergent,action
R10559 T21034 T21031 dobj action,regulating
R10560 T21035 T21034 prep of,action
R10561 T21036 T21035 pobj IL-6,of
R10562 T21037 T21036 cc and,IL-6
R10563 T21038 T21039 compound IL-10,[
R10564 T21039 T21034 appos [,action
R10565 T21040 T21041 nummod "8,9",]
R10566 T21041 T21039 appos ],[
R10567 T21042 T21016 punct .,shown
R10568 T21043 T21048 prep On,is
R10569 T21044 T21045 det the,contrary
R10570 T21045 T21043 pobj contrary,On
R10571 T21046 T21048 punct ",",is
R10572 T21047 T21048 nsubj SOCS1,is
R10573 T21048 T21048 ROOT is,is
R10574 T21049 T21048 acomp able,is
R10575 T21050 T21052 aux to,inhibit
R10576 T21051 T21052 advmod partially,inhibit
R10577 T21052 T21049 xcomp inhibit,able
R10578 T21053 T21055 amod IL-10-mediated,activation
R10579 T21054 T21055 nummod STAT3,activation
R10580 T21055 T21052 dobj activation,inhibit
R10581 T21056 T21055 cc and,activation
R10582 T21057 T21058 amod cellular,responses
R10583 T21058 T21055 conj responses,activation
R10584 T21059 T21052 punct ",",inhibit
R10585 T21060 T21062 advmod as,as
R10586 T21061 T21062 advmod well,as
R10587 T21062 T21052 cc as,inhibit
R10588 T21063 T21065 amod IFN-γ-mediated,activation
R10589 T21064 T21065 compound STAT1,activation
R10590 T21065 T21052 dobj activation,inhibit
R10591 T21066 T21068 nmod [,]
R10592 T21067 T21068 nummod 32,]
R10593 T21068 T21065 appos ],activation
R10594 T21069 T21048 punct .,is
R10595 T21070 T21071 aux To,determine
R10596 T21071 T21100 advcl determine,+
R10597 T21072 T21075 mark whether,involved
R10598 T21073 T21075 nsubjpass SOCSs,involved
R10599 T21074 T21075 auxpass were,involved
R10600 T21075 T21071 ccomp involved,determine
R10601 T21076 T21075 prep in,involved
R10602 T21077 T21081 det the,activation
R10603 T21078 T21081 amod defective,activation
R10604 T21079 T21081 amod IL-10-induced,activation
R10605 T21080 T21081 nummod STAT3,activation
R10606 T21081 T21076 pobj activation,in
R10607 T21082 T21081 prep of,activation
R10608 T21083 T21084 compound RA,CD4
R10609 T21084 T21082 pobj CD4,of
R10610 T21085 T21087 amod +,cells
R10611 T21086 T21087 compound T,cells
R10612 T21087 T21081 conj cells,activation
R10613 T21088 T21100 punct ",",+
R10614 T21089 T21090 det the,levels
R10615 T21090 T21100 nsubj levels,+
R10616 T21091 T21090 prep of,levels
R10617 T21092 T21091 pobj SOCS1,of
R10618 T21093 T21092 cc and,SOCS1
R10619 T21094 T21095 compound SOCS3,mRNA
R10620 T21095 T21096 compound mRNA,expression
R10621 T21096 T21090 conj expression,levels
R10622 T21097 T21096 prep in,expression
R10623 T21098 T21099 compound PB,CD4
R10624 T21099 T21097 pobj CD4,in
R10625 T21100 T21100 ROOT +,+
R10626 T21101 T21102 compound T,cells
R10627 T21102 T21100 dobj cells,+
R10628 T21103 T21102 prep from,cells
R10629 T21104 T21106 amod active,patients
R10630 T21105 T21106 compound RA,patients
R10631 T21106 T21103 pobj patients,from
R10632 T21107 T21103 cc and,from
R10633 T21108 T21103 conj from,from
R10634 T21109 T21110 amod healthy,controls
R10635 T21110 T21108 pobj controls,from
R10636 T21111 T21112 auxpass were,compared
R10637 T21112 T21100 prep compared,+
R10638 T21113 T21112 agent by,compared
R10639 T21114 T21116 amod semiquantitative,PCR
R10640 T21115 T21116 amod real-time,PCR
R10641 T21116 T21113 pobj PCR,by
R10642 T21117 T21100 punct .,+
R10643 T21118 T21120 det The,CD4
R10644 T21119 T21120 compound RA,CD4
R10645 T21120 T21124 nsubj CD4,contained
R10646 T21121 T21123 amod +,cells
R10647 T21122 T21123 compound T,cells
R10648 T21123 T21124 nsubj cells,contained
R10649 T21124 T21124 ROOT contained,contained
R10650 T21125 T21126 amod higher,levels
R10651 T21126 T21124 dobj levels,contained
R10652 T21127 T21126 prep of,levels
R10653 T21128 T21127 pobj SOCS1,of
R10654 T21129 T21128 cc but,SOCS1
R10655 T21130 T21131 amod lower,levels
R10656 T21131 T21127 pobj levels,of
R10657 T21132 T21131 prep of,levels
R10658 T21133 T21134 nummod SOCS3,transcripts
R10659 T21134 T21132 pobj transcripts,of
R10660 T21135 T21137 mark than,control
R10661 T21136 T21137 aux did,control
R10662 T21137 T21124 advcl control,contained
R10663 T21138 T21141 nmod CD4,cells
R10664 T21139 T21141 nummod +,cells
R10665 T21140 T21141 compound T,cells
R10666 T21141 T21137 dobj cells,control
R10667 T21142 T21141 punct (,cells
R10668 T21143 T21144 compound Fig.,6a
R10669 T21144 T21141 appos 6a,cells
R10670 T21145 T21141 punct ),cells
R10671 T21146 T21124 punct .,contained
R10672 T21147 T21148 amod Constitutive,expression
R10673 T21148 T21158 nsubj expression,was
R10674 T21149 T21148 prep of,expression
R10675 T21150 T21151 nummod SOCS1,mRNA
R10676 T21151 T21157 nmod mRNA,cells
R10677 T21152 T21151 prep in,mRNA
R10678 T21153 T21154 compound RA,CD4
R10679 T21154 T21152 pobj CD4,in
R10680 T21155 T21157 amod +,cells
R10681 T21156 T21157 compound T,cells
R10682 T21157 T21149 pobj cells,of
R10683 T21158 T21158 ROOT was,was
R10684 T21159 T21158 acomp comparable,was
R10685 T21160 T21159 prep with,comparable
R10686 T21161 T21162 det the,expression
R10687 T21162 T21160 pobj expression,with
R10688 T21163 T21162 prep in,expression
R10689 T21164 T21168 amod normal,cells
R10690 T21165 T21168 compound CD4,cells
R10691 T21166 T21168 nummod +,cells
R10692 T21167 T21168 compound T,cells
R10693 T21168 T21163 pobj cells,in
R10694 T21169 T21162 acl stimulated,expression
R10695 T21170 T21169 agent by,stimulated
R10696 T21171 T21173 nummod 10,IL-6
R10697 T21172 T21173 compound ng/ml,IL-6
R10698 T21173 T21170 pobj IL-6,by
R10699 T21174 T21175 punct (,Fig.
R10700 T21175 T21173 appos Fig.,IL-6
R10701 T21176 T21175 nummod 6b,Fig.
R10702 T21177 T21175 punct ),Fig.
R10703 T21178 T21158 punct ",",was
R10704 T21179 T21158 advcl supporting,was
R10705 T21180 T21182 poss its,significance
R10706 T21181 T21182 amod functional,significance
R10707 T21182 T21179 dobj significance,supporting
R10708 T21183 T21158 punct .,was
R10709 T21184 T21187 amod Defective,activation
R10710 T21185 T21187 amod IL-10-induced,activation
R10711 T21186 T21187 nummod STAT3,activation
R10712 T21187 T21189 nsubj activation,appears
R10713 T21188 T21189 advmod therefore,appears
R10714 T21189 T21189 ROOT appears,appears
R10715 T21190 T21191 aux to,be
R10716 T21191 T21189 xcomp be,appears
R10717 T21192 T21191 acomp due,be
R10718 T21193 T21194 advmod at,least
R10719 T21194 T21195 advmod least,in
R10720 T21195 T21192 prep in,due
R10721 T21196 T21195 pobj part,in
R10722 T21197 T21191 prep to,be
R10723 T21198 T21199 det an,abundance
R10724 T21199 T21197 pobj abundance,to
R10725 T21200 T21199 prep of,abundance
R10726 T21201 T21200 pobj SOCS1,of
R10727 T21202 T21199 prep in,abundance
R10728 T21203 T21204 compound RA,CD4
R10729 T21204 T21202 pobj CD4,in
R10730 T21205 T21207 amod +,cells
R10731 T21206 T21207 compound T,cells
R10732 T21207 T21197 pobj cells,to
R10733 T21208 T21189 punct .,appears

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T20609 8393-8402 Positive_regulation denotes abundance
T20608 8366-8369 Positive_regulation denotes due
T20607 8331-8341 Positive_regulation denotes activation
T20606 8415-8421 Protein denotes RA CD4
T20605 8406-8411 Protein denotes SOCS1
T20604 8325-8330 Protein denotes STAT3
T20603 8120-8130 Gene_expression denotes expression
T20602 8251-8258 Protein denotes Fig. 6b
T20601 8245-8249 Protein denotes IL-6
T20600 8209-8213 Protein denotes CD4+
T20599 8148-8154 Protein denotes RA CD4
T20598 8134-8144 Protein denotes SOCS1 mRNA
T20597 8075-8082 Regulation denotes control
T20596 8038-8044 Positive_regulation denotes levels
T20595 8012-8018 Positive_regulation denotes levels
T20594 8097-8104 Protein denotes Fig. 6a
T20593 8083-8087 Protein denotes CD4+
T20592 8048-8065 Protein denotes SOCS3 transcripts
T20591 8022-8027 Protein denotes SOCS1
T20590 7979-7986 Protein denotes RA CD4+
T20589 7766-7773 Positive_regulation denotes induced
T20588 7846-7856 Gene_expression denotes expression
T20587 7846-7856 Gene_expression denotes expression
T20586 7780-7790 Positive_regulation denotes activation
T20585 7860-7866 Protein denotes PB CD4
T20584 7835-7845 Protein denotes SOCS3 mRNA
T20583 7825-7830 Protein denotes SOCS1
T20582 7794-7800 Protein denotes RA CD4
T20581 7774-7779 Protein denotes STAT3
T20580 7760-7765 Protein denotes IL-10
T20579 7589-7596 Negative_regulation denotes inhibit
T20578 7670-7678 Positive_regulation denotes mediated
T20577 7679-7684 Protein denotes STAT1
T20576 7664-7669 Protein denotes IFN-γ
T20575 7612-7617 Protein denotes STAT3
T20574 7597-7602 Protein denotes IL-10
T20573 7562-7567 Protein denotes SOCS1
T20572 7488-7498 Regulation denotes regulating
T20571 7488-7498 Regulation denotes regulating
T20570 7532-7537 Protein denotes IL-10
T20569 7523-7527 Protein denotes IL-6
T20568 7457-7461 Protein denotes IL-6
T20567 7429-7434 Protein denotes STAT3
T20566 7375-7380 Protein denotes SOCS3
T20565 7163-7173 Negative_regulation denotes inhibitors
T20564 7163-7173 Negative_regulation denotes inhibitors
T20563 7193-7207 Protein denotes SOCS3 proteins
T20562 7183-7188 Protein denotes SOCS1
T20561 7177-7181 Protein denotes JAKs
T20560 7139-7143 Protein denotes IL-6
T20559 7090-7094 Positive_regulation denotes High
T20558 7090-7094 Positive_regulation denotes High
T20557 7095-7105 Gene_expression denotes expression
T20556 7095-7105 Gene_expression denotes expression
T20555 7123-7138 Protein denotes RA CD4+ T cells
T20554 7109-7119 Protein denotes SOCS1 mRNA
T18391 7072-7078 Protein denotes RA CD4
T18390 7063-7068 Protein denotes IL-10
T18389 6999-7004 Protein denotes STAT3
T18388 6947-6957 Protein denotes serum IL-6
T18387 6724-6731 Negative_regulation denotes reduced
T18386 6747-6757 Negative_regulation denotes inhibition
T18385 6767-6777 Gene_expression denotes production
T18384 6873-6878 Protein denotes IL-10
T18383 6828-6832 Protein denotes IL-6
T18382 6761-6766 Protein denotes IFN-γ
T18381 6732-6737 Protein denotes IL-10
T18380 6656-6666 Gene_expression denotes production
T18352 5853-5859 Positive_regulation denotes induce
T18351 5853-5859 Positive_regulation denotes induce
T18350 5959-5973 Negative_regulation denotes neutralization
T18349 5959-5973 Negative_regulation denotes neutralization
T18348 5924-5934 Positive_regulation denotes activation
T18347 5869-5884 Phosphorylation denotes phosphorylation
T18346 5869-5884 Phosphorylation denotes phosphorylation
T18345 5860-5868 Entity denotes tyrosine
T18344 5992-5999 Protein denotes Fig. 5a
T18343 5977-5981 Protein denotes IL-6
T18342 5918-5923 Protein denotes STAT3
T18341 5902-5907 Protein denotes STAT1
T18340 5888-5893 Protein denotes STAT3
T18339 5777-5792 Phosphorylation denotes phosphorylation
T18338 5715-5727 Positive_regulation denotes neutralizing
T18337 5772-5776 Protein denotes STAT
T18336 5728-5766 Protein denotes anti-IL-6 antibody or control antibody
T18335 5602-5605 Protein denotes CD4
T18334 5491-5500 Positive_regulation denotes activated
T18333 5491-5500 Positive_regulation denotes activated
T18332 5491-5500 Positive_regulation denotes activated
T18331 5491-5500 Positive_regulation denotes activated
T18330 5471-5486 Phosphorylation denotes phosphorylation
T18329 5471-5486 Phosphorylation denotes phosphorylation
T18328 5519-5523 Protein denotes CD4+
T18327 5504-5508 Protein denotes IL-6
T18326 5465-5470 Protein denotes STAT3
T18325 5455-5460 Protein denotes STAT1
T18324 5352-5363 Positive_regulation denotes responsible
T18323 5425-5435 Negative_regulation denotes inhibition
T18322 5390-5400 Positive_regulation denotes activation
T18321 5300-5314 Positive_regulation denotes concentrations
T18320 5419-5424 Protein denotes IL-10
T18319 5384-5389 Protein denotes STAT3
T18318 5318-5322 Protein denotes IL-6
T18317 5279-5283 Protein denotes CD4+
T18316 5144-5148 Protein denotes IL-6
T18315 5070-5077 Positive_regulation denotes induces
T18314 5091-5101 Positive_regulation denotes activation
T18313 4743-4752 Positive_regulation denotes activated
T18312 5105-5110 Protein denotes STAT3
T18311 5019-5023 Protein denotes IL-6
T18310 4873-4885 Protein denotes oncostatin M
T18309 4834-4839 Protein denotes IL-11
T18308 4734-4739 Protein denotes STAT3
T18307 4684-4694 Negative_regulation denotes inhibition
T18306 4649-4657 Positive_regulation denotes mediated
T18305 4704-4710 Regulation denotes effect
T18304 4664-4679 Phosphorylation denotes phosphorylation
T18303 4721-4725 Protein denotes CD4+
T18302 4698-4703 Protein denotes IL-10
T18301 4658-4663 Protein denotes STAT3
T18300 4644-4648 Protein denotes IL-6
T18379 6650-6655 Protein denotes IFN-γ
T18378 6565-6569 Protein denotes CD28
T18377 6557-6560 Protein denotes CD3
T18376 6525-6529 Protein denotes CD4+
T18375 6412-6419 Negative_regulation denotes inhibit
T18374 6426-6436 Gene_expression denotes production
T18373 6440-6444 Protein denotes CD4+
T18372 6420-6425 Protein denotes IFN-γ
T18371 6403-6408 Protein denotes IL-10
T18370 6369-6373 Protein denotes IL-6
T18369 6213-6221 Positive_regulation denotes required
T18368 6120-6124 Negative_regulation denotes lack
T18367 6323-6330 Positive_regulation denotes present
T18366 6286-6296 Negative_regulation denotes inhibitors
T18365 6266-6276 Positive_regulation denotes activation
T18364 6232-6242 Positive_regulation denotes activation
T18363 6183-6197 Positive_regulation denotes concentrations
T18362 6134-6144 Positive_regulation denotes activation
T18361 6300-6305 Protein denotes STAT1
T18360 6260-6265 Protein denotes STAT3
T18359 6226-6231 Protein denotes STAT1
T18358 6201-6205 Protein denotes IL-6
T18357 6128-6133 Protein denotes STAT1
T18356 6042-6074 Protein denotes dominant STAT3-activating factor
T18355 6030-6034 Protein denotes IL-6
T18354 5946-5955 Negative_regulation denotes abolished
T18353 5946-5955 Negative_regulation denotes abolished
T16123 4626-4641 Phosphorylation denotes phosphorylation
T16122 4485-4500 Positive_regulation denotes IL-10-activated
T16121 4485-4500 Positive_regulation denotes IL-10-activated
T16120 4620-4625 Protein denotes STAT3
T16119 4541-4546 Protein denotes STAT3
T16118 4527-4532 Protein denotes IL-10
T16117 4509-4513 Protein denotes CD4+
T16116 4501-4505 Protein denotes STAT
T16115 4466-4471 Protein denotes STAT3
T16114 4325-4338 Positive_regulation denotes IL-10-induced
T16113 4369-4377 Positive_regulation denotes detected
T16112 4345-4360 Phosphorylation denotes phosphorylation
T16111 4428-4435 Protein denotes Fig. 4a
T16110 4414-4418 Protein denotes CD4+
T16109 4388-4394 Protein denotes RA CD4
T16108 4339-4344 Protein denotes STAT1
T16107 4232-4239 Positive_regulation denotes induced
T16106 4216-4225 Negative_regulation denotes defective
T16105 4267-4272 Positive_regulation denotes found
T16104 4267-4272 Positive_regulation denotes found
T16103 4246-4261 Phosphorylation denotes phosphorylation
T16102 4196-4211 Phosphorylation denotes phosphorylation
T16101 4296-4303 Protein denotes Fig. 4c
T16100 4282-4285 Protein denotes CD4
T16099 4276-4281 Protein denotes RA ST
T16098 4240-4245 Protein denotes STAT3
T16097 4226-4231 Protein denotes IL-10
T16096 4190-4195 Protein denotes STAT3
T16095 4115-4124 Positive_regulation denotes augmented
T16094 4095-4110 Phosphorylation denotes phosphorylation
T16093 4089-4094 Protein denotes STAT3
T16092 4059-4069 Positive_regulation denotes detectable
T16091 4039-4054 Phosphorylation denotes phosphorylation
T16090 3958-3972 Phosphorylation denotes phosphorylated
T16089 4033-4038 Protein denotes STAT3
T16088 3993-3999 Protein denotes PB CD4
T16087 3948-3953 Protein denotes STAT3
T16086 3856-3863 Positive_regulation denotes induced
T16085 3876-3886 Positive_regulation denotes activation
T16084 3856-3863 Positive_regulation denotes induced
T16083 3819-3834 Phosphorylation denotes phosphorylation
T16082 3922-3932 Protein denotes Fig. 4a,4b
T16081 3908-3912 Protein denotes CD4+
T16080 3870-3875 Protein denotes IL-10
T16079 3813-3818 Protein denotes STAT3
T16078 3653-3662 Positive_regulation denotes induction
T16077 3653-3662 Positive_regulation denotes induction
T16076 3682-3697 Phosphorylation denotes phosphorylation
T16075 3682-3697 Phosphorylation denotes phosphorylation
T16074 3653-3662 Positive_regulation denotes induction
T16073 3653-3662 Positive_regulation denotes induction
T16072 3710-3716 Protein denotes PB CD4
T16071 3701-3706 Protein denotes IL-10
T16070 3676-3681 Protein denotes STAT3
T16069 3666-3671 Protein denotes STAT1
T16068 3628-3642 Positive_regulation denotes overexpression
T16067 3628-3642 Gene_expression denotes overexpression
T16066 3423-3432 Negative_regulation denotes deficient
T16065 3622-3627 Protein denotes STAT3
T16064 3487-3492 Protein denotes IL-10
T16063 3456-3461 Protein denotes STAT3
T16062 3417-3422 Protein denotes STAT3
T16061 3300-3308 Entity denotes tyrosine
T16060 3259-3270 Binding denotes interaction
T16059 3386-3391 Protein denotes STAT3
T16058 3376-3381 Protein denotes STAT1
T16057 3286-3291 Protein denotes IL-10
T16056 3274-3280 Protein denotes IL-10R
T16055 3205-3213 Positive_regulation denotes mediated
T16054 3205-3213 Positive_regulation denotes mediated
T16053 3189-3198 Negative_regulation denotes Defective
T16052 3189-3198 Negative_regulation denotes Defective
T16051 3220-3235 Phosphorylation denotes phosphorylation
T16050 3220-3235 Phosphorylation denotes phosphorylation
T16049 3239-3254 Protein denotes RA CD4+ T cells
T16048 3214-3219 Protein denotes STAT3
T16047 3199-3204 Protein denotes IL-10
T14839 3161-3165 Protein denotes CD4+
T14838 3136-3141 Protein denotes IL-10
T14837 3000-3009 Positive_regulation denotes increased
T14836 2955-2965 Gene_expression denotes expression
T14835 2969-2973 Protein denotes CD4+
T14834 2947-2954 Protein denotes IL-10R1
T14833 2918-2921 Protein denotes Fig
T14832 2771-2781 Gene_expression denotes expression
T14831 2684-2694 Negative_regulation denotes inhibition
T14830 2796-2802 Protein denotes PB CD4
T14829 2785-2792 Protein denotes IL-10R1
T14828 2698-2704 Protein denotes RA CD4
T14827 2678-2683 Protein denotes IL-10
T14826 2571-2581 Gene_expression denotes expression
T14825 2563-2570 Protein denotes IL-10R1
T14824 2439-2444 Protein denotes IL-10
T14823 2340-2349 Positive_regulation denotes Increased
T14822 2350-2360 Gene_expression denotes expression
T14821 2388-2403 Protein denotes RA CD4+ T cells
T13064 2308-2313 Protein denotes IL-10
T13063 2237-2240 Protein denotes CD4
T13062 2031-2039 Regulation denotes affected
T13061 2012-2022 Gene_expression denotes production
T13060 2007-2011 Protein denotes IL-2
T13059 1943-1948 Protein denotes IL-10
T13058 1905-1909 Protein denotes CD28
T13057 1897-1900 Protein denotes CD3
T13056 1878-1882 Protein denotes CD4+
T13055 1824-1831 Protein denotes Fig. 2a
T13054 1810-1814 Protein denotes CD4+
T13053 1755-1760 Protein denotes IFN-γ
T13052 1692-1696 Protein denotes CD4+
T13051 1447-1457 Gene_expression denotes production
T13050 1447-1457 Gene_expression denotes production
T13049 1342-1352 Gene_expression denotes production
T13048 1342-1352 Gene_expression denotes production
T13047 1441-1446 Protein denotes IFN-γ
T13046 1432-1437 Protein denotes IL-10
T13045 1393-1400 Protein denotes Fig. 2a
T13044 1336-1341 Protein denotes IFN-γ
T13043 1014-1024 Gene_expression denotes production
T13042 1230-1233 Protein denotes CRP
T13041 1173-1176 Protein denotes CRP
T13040 1055-1059 Protein denotes CD28
T13039 1047-1050 Protein denotes CD3
T13038 1028-1032 Protein denotes CD4+
T13037 1008-1013 Protein denotes IFN-γ
T13036 823-830 Gene_expression denotes produce
T13035 941-946 Protein denotes IL-10
T13034 854-859 Protein denotes IFN-γ
T13033 794-800 Protein denotes RA CD4
T13032 732-741 Negative_regulation denotes inhibited
T13031 677-687 Gene_expression denotes production
T13030 708-712 Protein denotes CD4+
T13029 671-676 Protein denotes IFN-γ
T13028 663-666 Protein denotes Fig
T13027 617-627 Gene_expression denotes production
T13026 611-616 Protein denotes IFN-γ
T13025 587-592 Protein denotes IL-10
T13024 526-544 Protein denotes anti-CD28 antibody
T13023 504-521 Protein denotes anti-CD3 antibody
T13022 393-396 Protein denotes CD4
T13021 374-379 Protein denotes IL-10
T13020 355-361 Protein denotes RA CD4
T13019 229-239 Negative_regulation denotes inhibiting
T13018 229-239 Negative_regulation denotes inhibiting
T13017 274-281 Binding denotes binding
T13016 254-269 Phosphorylation denotes phosphorylation
T13015 245-253 Entity denotes tyrosine
T13014 285-314 Protein denotes phosphatidylinositol 3-kinase
T13013 240-244 Protein denotes CD28
T13012 83-87 Protein denotes CD28
T13011 29-39 Negative_regulation denotes inhibition
T13010 49-59 Gene_expression denotes production
T13009 9-19 Gene_expression denotes Resistance
T13008 63-78 Protein denotes RA CD4+ T cells
T13007 43-48 Protein denotes IFN-γ
T13006 23-28 Protein denotes IL-10
R6395 T13006 T13009 themeOf IL-10,Resistance
R6396 T13007 T13010 themeOf IFN-γ,production
R6397 T13010 T13011 themeOf production,inhibition
R6398 T13013 T13016 themeOf CD28,phosphorylation
R6399 T13013 T13015 partOf CD28,tyrosine
R6400 T13014 T13017 themeOf phosphatidylinositol 3-kinase,binding
R6401 T13015 T13016 Site tyrosine,phosphorylation
R6402 T13016 T13018 themeOf phosphorylation,inhibiting
R6403 T13017 T13019 themeOf binding,inhibiting
R6404 T13026 T13027 themeOf IFN-γ,production
R6405 T13029 T13031 themeOf IFN-γ,production
R6406 T13031 T13032 themeOf production,inhibited
R6407 T13034 T13036 themeOf IFN-γ,produce
R6408 T13037 T13043 themeOf IFN-γ,production
R6409 T13044 T13048 themeOf IFN-γ,production
R6410 T13045 T13049 themeOf Fig. 2a,production
R6411 T13046 T13050 themeOf IL-10,production
R6412 T13047 T13051 themeOf IFN-γ,production
R6413 T13060 T13061 themeOf IL-2,production
R6414 T13061 T13062 themeOf production,affected
R7451 T14821 T14822 themeOf RA CD4+ T cells,expression
R7452 T14822 T14823 themeOf expression,Increased
R7453 T14825 T14826 themeOf IL-10R1,expression
R7454 T14827 T14831 themeOf IL-10,inhibition
R7455 T14829 T14832 themeOf IL-10R1,expression
R7456 T14834 T14836 themeOf IL-10R1,expression
R7457 T14836 T14837 themeOf expression,increased
R7982 T16085 T16086 causeOf activation,induced
R7983 T16087 T16090 themeOf STAT3,phosphorylated
R7984 T16089 T16091 themeOf STAT3,phosphorylation
R7985 T16091 T16092 themeOf phosphorylation,detectable
R7986 T16093 T16094 themeOf STAT3,phosphorylation
R7987 T16094 T16095 themeOf phosphorylation,augmented
R7988 T16096 T16102 themeOf STAT3,phosphorylation
R7989 T16097 T16107 causeOf IL-10,induced
R7990 T16098 T16103 themeOf STAT3,phosphorylation
R7991 T16102 T16104 themeOf phosphorylation,found
R7992 T16103 T16105 themeOf phosphorylation,found
R7993 T16103 T16106 themeOf phosphorylation,defective
R7994 T16103 T16107 themeOf phosphorylation,induced
R7995 T16108 T16112 themeOf STAT1,phosphorylation
R7996 T16112 T16113 themeOf phosphorylation,detected
R7997 T16112 T16114 themeOf phosphorylation,IL-10-induced
R7998 T16115 T16121 themeOf STAT3,IL-10-activated
R7999 T16116 T16122 themeOf STAT,IL-10-activated
R8000 T16120 T16123 themeOf STAT3,phosphorylation
R8948 T18357 T18362 themeOf STAT1,activation
R8949 T18358 T18363 themeOf IL-6,concentrations
R8950 T18359 T18364 themeOf STAT1,activation
R8951 T18360 T18365 themeOf STAT3,activation
R8952 T18361 T18366 themeOf STAT1,inhibitors
R8953 T18362 T18368 themeOf activation,lack
R8954 T18364 T18369 themeOf activation,required
R8955 T18366 T18367 themeOf inhibitors,present
R8956 T18371 T18375 causeOf IL-10,inhibit
R8957 T18372 T18374 themeOf IFN-γ,production
R8958 T18374 T18375 themeOf production,inhibit
R8959 T18379 T18380 themeOf IFN-γ,production
R8960 T18381 T18386 causeOf IL-10,inhibition
R8961 T18382 T18385 themeOf IFN-γ,production
R8962 T18385 T18386 themeOf production,inhibition
R8963 T18386 T18387 themeOf inhibition,reduced
R10191 T20554 T20556 themeOf SOCS1 mRNA,expression
R10192 T20555 T20557 themeOf RA CD4+ T cells,expression
R10193 T20556 T20558 themeOf expression,High
R10194 T20557 T20559 themeOf expression,High
R8909 T18300 T18306 causeOf IL-6,mediated
R8910 T18301 T18304 themeOf STAT3,phosphorylation
R8911 T18302 T18305 themeOf IL-10,effect
R8912 T18304 T18306 themeOf phosphorylation,mediated
R8913 T18305 T18307 themeOf effect,inhibition
R8914 T18308 T18313 themeOf STAT3,activated
R8915 T18312 T18314 themeOf STAT3,activation
R8916 T18314 T18315 themeOf activation,induces
R8917 T18318 T18321 themeOf IL-6,concentrations
R8918 T18319 T18322 themeOf STAT3,activation
R8919 T18320 T18323 themeOf IL-10,inhibition
R8920 T18322 T18324 themeOf activation,responsible
R8921 T18325 T18329 themeOf STAT1,phosphorylation
R8923 T18326 T18330 themeOf STAT3,phosphorylation
R8925 T18327 T18331 causeOf IL-6,activated
R10195 T20561 T20564 themeOf JAKs,inhibitors
R10196 T20563 T20565 themeOf SOCS3 proteins,inhibitors
R10197 T20569 T20571 themeOf IL-6,regulating
R10198 T20570 T20572 themeOf IL-10,regulating
R10199 T20573 T20579 causeOf SOCS1,inhibit
R10200 T20576 T20578 causeOf IFN-γ,mediated
R10201 T20577 T20578 themeOf STAT1,mediated
R10202 T20578 T20579 themeOf mediated,inhibit
R10203 T20580 T20589 causeOf IL-10,induced
R10204 T20581 T20586 themeOf STAT3,activation
R10205 T20583 T20587 themeOf SOCS1,expression
R10206 T20584 T20588 themeOf SOCS3 mRNA,expression
R10207 T20586 T20589 themeOf activation,induced
R10208 T20591 T20595 themeOf SOCS1,levels
R10209 T20592 T20596 themeOf SOCS3 transcripts,levels
R10210 T20594 T20597 themeOf Fig. 6a,control
R10211 T20598 T20603 themeOf SOCS1 mRNA,expression
R10212 T20604 T20607 themeOf STAT3,activation
R10213 T20605 T20609 themeOf SOCS1,abundance
R10214 T20607 T20608 themeOf activation,due
R8922 T18325 T18331 themeOf STAT1,activated
R8924 T18326 T18332 themeOf STAT3,activated
R8926 T18327 T18332 causeOf IL-6,activated
R8927 T18327 T18333 causeOf IL-6,activated
R8928 T18327 T18334 causeOf IL-6,activated
R8929 T18329 T18333 themeOf phosphorylation,activated
R8930 T18330 T18334 themeOf phosphorylation,activated
R8931 T18336 T18338 themeOf anti-IL-6 antibody or control antibody,neutralizing
R8932 T18337 T18339 themeOf STAT,phosphorylation
R8933 T18340 T18346 themeOf STAT3,phosphorylation
R8934 T18340 T18345 partOf STAT3,tyrosine
R8935 T18341 T18347 themeOf STAT1,phosphorylation
R8936 T18341 T18345 partOf STAT1,tyrosine
R8937 T18342 T18348 themeOf STAT3,activation
R8938 T18343 T18349 themeOf IL-6,neutralization
R8939 T18344 T18350 themeOf Fig. 5a,neutralization
R8940 T18345 T18346 Site tyrosine,phosphorylation
R8941 T18345 T18347 Site tyrosine,phosphorylation
R8942 T18346 T18351 themeOf phosphorylation,induce
R8943 T18347 T18352 themeOf phosphorylation,induce
R8944 T18348 T18353 themeOf activation,abolished
R8945 T18348 T18354 themeOf activation,abolished
R8946 T18349 T18353 causeOf neutralization,abolished
R8947 T18350 T18354 causeOf neutralization,abolished
R7952 T16047 T16054 causeOf IL-10,mediated
R7953 T16047 T16055 causeOf IL-10,mediated
R7954 T16048 T16050 themeOf STAT3,phosphorylation
R7955 T16049 T16051 themeOf RA CD4+ T cells,phosphorylation
R7956 T16050 T16052 themeOf phosphorylation,Defective
R7957 T16050 T16054 themeOf phosphorylation,mediated
R7958 T16051 T16053 themeOf phosphorylation,Defective
R7959 T16051 T16055 themeOf phosphorylation,mediated
R7960 T16056 T16060 themeOf IL-10R,interaction
R7961 T16057 T16060 themeOf IL-10,interaction
R7962 T16058 T16061 partOf STAT1,tyrosine
R7963 T16059 T16061 partOf STAT3,tyrosine
R7964 T16062 T16066 themeOf STAT3,deficient
R7965 T16065 T16067 themeOf STAT3,overexpression
R7966 T16067 T16068 themeOf overexpression,overexpression
R7967 T16069 T16073 themeOf STAT1,induction
R7968 T16069 T16075 themeOf STAT1,phosphorylation
R7969 T16070 T16074 themeOf STAT3,induction
R7970 T16070 T16076 themeOf STAT3,phosphorylation
R7971 T16071 T16073 causeOf IL-10,induction
R7972 T16071 T16074 causeOf IL-10,induction
R7973 T16071 T16077 causeOf IL-10,induction
R7974 T16071 T16078 causeOf IL-10,induction
R7975 T16075 T16077 themeOf phosphorylation,induction
R7976 T16076 T16078 themeOf phosphorylation,induction
R7977 T16079 T16083 themeOf STAT3,phosphorylation
R7978 T16080 T16085 themeOf IL-10,activation
R7979 T16082 T16084 causeOf "Fig. 4a,4b",induced
R7980 T16083 T16084 themeOf phosphorylation,induced
R7981 T16083 T16086 themeOf phosphorylation,induced

test3

Id Subject Object Predicate Lexical cue
T15572 4620-4625 Protein denotes STAT3
T17456 7075-7078 Protein denotes CD4
T20150 8418-8421 Protein denotes CD4
T20149 8406-8411 Protein denotes SOCS1
T20148 8366-8369 Positive_regulation denotes due
T20147 8331-8341 Positive_regulation denotes activation
T20146 8325-8330 Protein denotes STAT3
T20145 8317-8324 Positive_regulation denotes induced
T20144 8311-8316 Protein denotes IL-10
T20143 8301-8310 Negative_regulation denotes Defective
T20142 8245-8249 Protein denotes IL-6
T20141 8209-8212 Protein denotes CD4
T20140 8188-8198 Gene_expression denotes expression
T20139 8151-8154 Protein denotes CD4
T20138 8134-8139 Protein denotes SOCS1
T20137 8120-8130 Gene_expression denotes expression
T20136 8083-8086 Protein denotes CD4
T20135 8048-8053 Protein denotes SOCS3
T20134 8022-8027 Protein denotes SOCS1
T20133 7982-7985 Protein denotes CD4
T20132 7863-7866 Protein denotes CD4
T20131 7841-7856 Transcription denotes mRNA expression
T20130 7835-7840 Protein denotes SOCS3
T20129 7825-7830 Protein denotes SOCS1
T20128 7797-7800 Protein denotes CD4
T20127 7780-7790 Positive_regulation denotes activation
T20126 7774-7779 Protein denotes STAT3
T20125 7766-7773 Positive_regulation denotes induced
T20124 7760-7765 Protein denotes IL-10
T20123 7685-7695 Positive_regulation denotes activation
T20122 7679-7684 Protein denotes STAT1
T20121 7670-7678 Positive_regulation denotes mediated
T20120 7664-7669 Protein denotes IFN-γ
T20119 7618-7628 Positive_regulation denotes activation
T20118 7612-7617 Protein denotes STAT3
T20117 7603-7611 Positive_regulation denotes mediated
T20116 7597-7602 Protein denotes IL-10
T20115 7589-7596 Negative_regulation denotes inhibit
T20114 7562-7567 Protein denotes SOCS1
T20113 7532-7537 Protein denotes IL-10
T20112 7523-7527 Protein denotes IL-6
T20111 7488-7498 Regulation denotes regulating
T20110 7473-7478 Protein denotes IL-10
T20109 7457-7461 Protein denotes IL-6
T20108 7446-7453 Positive_regulation denotes induced
T20107 7435-7445 Positive_regulation denotes activation
T20106 7429-7434 Protein denotes STAT3
T20105 7421-7428 Negative_regulation denotes inhibit
T20104 7375-7380 Protein denotes SOCS3
T20103 7193-7198 Protein denotes SOCS3
T20102 7183-7188 Protein denotes SOCS1
T20101 7163-7173 Negative_regulation denotes inhibitors
T20100 7144-7151 Positive_regulation denotes induces
T20099 7139-7143 Protein denotes IL-6
T20098 7126-7129 Protein denotes CD4
T20097 7109-7114 Protein denotes SOCS1
T20096 7095-7105 Gene_expression denotes expression
T20095 7090-7094 Positive_regulation denotes High
T20094 8418-8421 Protein denotes CD4
T20093 8406-8411 Protein denotes SOCS1
T20092 8325-8330 Protein denotes STAT3
T20091 8311-8316 Protein denotes IL-10
T20090 8245-8249 Protein denotes IL-6
T20089 8209-8212 Protein denotes CD4
T20088 8151-8154 Protein denotes CD4
T20087 8134-8139 Protein denotes SOCS1
T20086 8083-8086 Protein denotes CD4
T20085 8048-8053 Protein denotes SOCS3
T20084 8022-8027 Protein denotes SOCS1
T20083 7982-7985 Protein denotes CD4
T20082 7863-7866 Protein denotes CD4
T20081 7835-7840 Protein denotes SOCS3
T20080 7825-7830 Protein denotes SOCS1
T20079 7797-7800 Protein denotes CD4
T20078 7774-7779 Protein denotes STAT3
T20077 7760-7765 Protein denotes IL-10
T20076 7679-7684 Protein denotes STAT1
T20075 7664-7669 Protein denotes IFN-γ
T20074 7612-7617 Protein denotes STAT3
T20073 7597-7602 Protein denotes IL-10
T20072 7562-7567 Protein denotes SOCS1
T20071 7532-7537 Protein denotes IL-10
T20070 7523-7527 Protein denotes IL-6
T20069 7473-7478 Protein denotes IL-10
T20068 7457-7461 Protein denotes IL-6
T20067 7429-7434 Protein denotes STAT3
T20066 7375-7380 Protein denotes SOCS3
T20065 7193-7198 Protein denotes SOCS3
T20064 7183-7188 Protein denotes SOCS1
T20063 7139-7143 Protein denotes IL-6
T20062 7126-7129 Protein denotes CD4
T20061 7109-7114 Protein denotes SOCS1
T17455 7063-7068 Protein denotes IL-10
T17454 7053-7059 Regulation denotes effect
T17453 7005-7015 Positive_regulation denotes activation
T17452 6999-7004 Protein denotes STAT3
T17451 6986-6995 Positive_regulation denotes induction
T17450 6969-6973 Regulation denotes role
T17449 6953-6957 Protein denotes IL-6
T17448 6873-6878 Protein denotes IL-10
T17447 6828-6832 Protein denotes IL-6
T17446 6767-6777 Gene_expression denotes production
T17445 6761-6766 Protein denotes IFN-γ
T17444 6747-6757 Negative_regulation denotes inhibition
T17443 6738-6746 Positive_regulation denotes mediated
T17442 6732-6737 Protein denotes IL-10
T17441 6724-6731 Negative_regulation denotes reduced
T17440 6690-6694 Protein denotes IL-6
T17439 6656-6666 Gene_expression denotes production
T17438 6650-6655 Protein denotes IFN-γ
T17437 6622-6627 Protein denotes IL-10
T17436 6603-6610 Negative_regulation denotes absence
T17435 6565-6569 Protein denotes CD28
T17434 6525-6528 Protein denotes CD4
T17433 6499-6503 Protein denotes IL-6
T17432 6440-6443 Protein denotes CD4
T17431 6426-6436 Gene_expression denotes production
T17430 6420-6425 Protein denotes IFN-γ
T17429 6412-6419 Negative_regulation denotes inhibit
T17428 6403-6408 Protein denotes IL-10
T17427 6393-6399 Regulation denotes effect
T17426 6380-6388 Negative_regulation denotes suppress
T17425 6369-6373 Protein denotes IL-6
T17424 6300-6305 Protein denotes STAT1
T17423 6286-6296 Negative_regulation denotes inhibitors
T17422 6266-6276 Positive_regulation denotes activation
T17421 6260-6265 Protein denotes STAT3
T17420 6232-6242 Positive_regulation denotes activation
T17419 6226-6231 Protein denotes STAT1
T17418 6213-6221 Positive_regulation denotes required
T17417 6201-6205 Protein denotes IL-6
T17416 6134-6144 Positive_regulation denotes activation
T17415 6128-6133 Protein denotes STAT1
T17414 6120-6124 Negative_regulation denotes lack
T17413 6051-6056 Protein denotes STAT3
T17412 6030-6034 Protein denotes IL-6
T17411 5977-5981 Protein denotes IL-6
T17410 5959-5973 Negative_regulation denotes neutralization
T17409 5946-5955 Negative_regulation denotes abolished
T17408 5924-5934 Positive_regulation denotes activation
T17407 5918-5923 Protein denotes STAT3
T17406 5902-5907 Protein denotes STAT1
T17405 5888-5893 Protein denotes STAT3
T17404 5869-5884 Phosphorylation denotes phosphorylation
T17403 5853-5859 Positive_regulation denotes induce
T17402 5777-5792 Phosphorylation denotes phosphorylation
T17401 5733-5737 Protein denotes IL-6
T17400 5602-5605 Protein denotes CD4
T17399 5519-5522 Protein denotes CD4
T17398 5504-5508 Protein denotes IL-6
T17397 5491-5500 Positive_regulation denotes activated
T17396 5471-5486 Phosphorylation denotes phosphorylation
T17395 5465-5470 Protein denotes STAT3
T17394 5455-5460 Protein denotes STAT1
T17393 5425-5435 Negative_regulation denotes inhibition
T17392 5419-5424 Protein denotes IL-10
T17391 5390-5400 Positive_regulation denotes activation
T17390 5384-5389 Protein denotes STAT3
T17389 5318-5322 Protein denotes IL-6
T17388 5279-5282 Protein denotes CD4
T17387 5144-5148 Protein denotes IL-6
T17386 5105-5110 Protein denotes STAT3
T17385 5091-5101 Positive_regulation denotes activation
T17384 5070-5077 Positive_regulation denotes induces
T17383 5019-5023 Protein denotes IL-6
T17382 4964-4969 Protein denotes IL-10
T17381 4924-4947 Protein denotes epidermal growth factor
T17380 4888-4918 Protein denotes platelet-derived growth factor
T17379 4873-4885 Protein denotes oncostatin M
T17378 4841-4867 Protein denotes leukemia inhibitory factor
T17377 4834-4839 Protein denotes IL-11
T17376 4828-4832 Protein denotes IL-6
T17375 4743-4752 Positive_regulation denotes activated
T17374 4734-4739 Protein denotes STAT3
T17373 4721-4724 Protein denotes CD4
T17372 4704-4710 Regulation denotes effect
T17371 4698-4703 Protein denotes IL-10
T17370 4684-4694 Negative_regulation denotes inhibition
T17369 4664-4679 Phosphorylation denotes phosphorylation
T17368 4658-4663 Protein denotes STAT3
T17367 4649-4657 Positive_regulation denotes mediated
T17366 4644-4648 Protein denotes IL-6
T17365 7075-7078 Protein denotes CD4
T17364 7063-7068 Protein denotes IL-10
T17363 6999-7004 Protein denotes STAT3
T17362 6953-6957 Protein denotes IL-6
T17361 6873-6878 Protein denotes IL-10
T17360 6828-6832 Protein denotes IL-6
T17359 6761-6766 Protein denotes IFN-γ
T17358 6732-6737 Protein denotes IL-10
T17357 6690-6694 Protein denotes IL-6
T17356 6650-6655 Protein denotes IFN-γ
T17355 6622-6627 Protein denotes IL-10
T17354 6565-6569 Protein denotes CD28
T17353 6525-6528 Protein denotes CD4
T17352 6499-6503 Protein denotes IL-6
T17351 6440-6443 Protein denotes CD4
T17350 6420-6425 Protein denotes IFN-γ
T17349 6403-6408 Protein denotes IL-10
T17348 6369-6373 Protein denotes IL-6
T17347 6300-6305 Protein denotes STAT1
T17346 6260-6265 Protein denotes STAT3
T17345 6226-6231 Protein denotes STAT1
T17344 6201-6205 Protein denotes IL-6
T17343 6128-6133 Protein denotes STAT1
T17342 6051-6056 Protein denotes STAT3
T17341 6030-6034 Protein denotes IL-6
T17340 5977-5981 Protein denotes IL-6
T17339 5918-5923 Protein denotes STAT3
T17338 5902-5907 Protein denotes STAT1
T17337 5888-5893 Protein denotes STAT3
T17336 5733-5737 Protein denotes IL-6
T17335 5602-5605 Protein denotes CD4
T17334 5519-5522 Protein denotes CD4
T17333 5504-5508 Protein denotes IL-6
T17332 5465-5470 Protein denotes STAT3
T17331 5455-5460 Protein denotes STAT1
T17330 5419-5424 Protein denotes IL-10
T17329 5384-5389 Protein denotes STAT3
T17328 5318-5322 Protein denotes IL-6
T17327 5279-5282 Protein denotes CD4
T17326 5144-5148 Protein denotes IL-6
T17325 5105-5110 Protein denotes STAT3
T17324 5019-5023 Protein denotes IL-6
T17323 4964-4969 Protein denotes IL-10
T17322 4924-4947 Protein denotes epidermal growth factor
T17321 4888-4918 Protein denotes platelet-derived growth factor
T17320 4873-4885 Protein denotes oncostatin M
T17319 4841-4867 Protein denotes leukemia inhibitory factor
T17318 4834-4839 Protein denotes IL-11
T17317 4828-4832 Protein denotes IL-6
T17316 4734-4739 Protein denotes STAT3
T17315 4721-4724 Protein denotes CD4
T17314 4698-4703 Protein denotes IL-10
T17313 4658-4663 Protein denotes STAT3
T17312 4644-4648 Protein denotes IL-6
T15573 4626-4641 Phosphorylation denotes phosphorylation
T15571 4610-4619 Positive_regulation denotes sustained
T15570 4593-4604 Binding denotes association
T15569 4565-4575 Negative_regulation denotes diminished
T15568 4547-4557 Positive_regulation denotes activation
T15567 4541-4546 Protein denotes STAT3
T15566 4533-4540 Positive_regulation denotes induced
T15565 4527-4532 Protein denotes IL-10
T15564 4509-4512 Protein denotes CD4
T15563 4491-4500 Positive_regulation denotes activated
T15562 4485-4490 Protein denotes IL-10
T15561 4466-4471 Protein denotes STAT3
T15560 4414-4417 Protein denotes CD4
T15559 4391-4394 Protein denotes CD4
T15558 4345-4360 Phosphorylation denotes phosphorylation
T15557 4339-4344 Protein denotes STAT1
T15556 4331-4338 Positive_regulation denotes induced
T15555 4325-4330 Protein denotes IL-10
T15554 4282-4285 Protein denotes CD4
T15553 4246-4261 Phosphorylation denotes phosphorylation
T15552 4240-4245 Protein denotes STAT3
T15551 4232-4239 Positive_regulation denotes induced
T15550 4226-4231 Protein denotes IL-10
T15549 4216-4225 Negative_regulation denotes defective
T15548 4196-4211 Phosphorylation denotes phosphorylation
T15547 4190-4195 Protein denotes STAT3
T15546 4180-4189 Positive_regulation denotes sustained
T15545 4168-4173 Protein denotes IL-10
T15544 4135-4144 Positive_regulation denotes activated
T15543 4115-4124 Positive_regulation denotes augmented
T15542 4095-4110 Phosphorylation denotes phosphorylation
T15541 4089-4094 Protein denotes STAT3
T15540 4039-4054 Phosphorylation denotes phosphorylation
T15539 4033-4038 Protein denotes STAT3
T15538 3996-3999 Protein denotes CD4
T15537 3958-3972 Phosphorylation denotes phosphorylated
T15536 3948-3953 Protein denotes STAT3
T15535 3908-3911 Protein denotes CD4
T15534 3876-3886 Positive_regulation denotes activation
T15533 3870-3875 Protein denotes IL-10
T15532 3856-3863 Positive_regulation denotes induced
T15531 3819-3834 Phosphorylation denotes phosphorylation
T15530 3813-3818 Protein denotes STAT3
T15529 3713-3716 Protein denotes CD4
T15528 3701-3706 Protein denotes IL-10
T15527 3682-3697 Phosphorylation denotes phosphorylation
T15526 3676-3681 Protein denotes STAT3
T15525 3666-3671 Protein denotes STAT1
T15524 3653-3662 Positive_regulation denotes induction
T15523 3628-3642 Positive_regulation denotes overexpression
T15522 3622-3627 Protein denotes STAT3
T15521 3487-3492 Protein denotes IL-10
T15520 3456-3461 Protein denotes STAT3
T15519 3423-3432 Negative_regulation denotes deficient
T15518 3417-3422 Protein denotes STAT3
T15517 3386-3391 Protein denotes STAT3
T15516 3376-3381 Protein denotes STAT1
T15515 3329-3339 Positive_regulation denotes activation
T15514 3309-3324 Phosphorylation denotes phosphorylation
T15513 3292-3299 Positive_regulation denotes induces
T15512 3286-3291 Protein denotes IL-10
T15511 3274-3280 Protein denotes IL-10R
T15510 3259-3270 Binding denotes interaction
T15509 3242-3245 Protein denotes CD4
T15508 3220-3235 Phosphorylation denotes phosphorylation
T15507 3214-3219 Protein denotes STAT3
T15506 3205-3213 Positive_regulation denotes mediated
T15505 3199-3204 Protein denotes IL-10
T15504 3189-3198 Negative_regulation denotes Defective
T15503 4620-4625 Protein denotes STAT3
T15502 4541-4546 Protein denotes STAT3
T15501 4527-4532 Protein denotes IL-10
T15500 4509-4512 Protein denotes CD4
T15499 4485-4490 Protein denotes IL-10
T15498 4466-4471 Protein denotes STAT3
T15497 4414-4417 Protein denotes CD4
T15496 4391-4394 Protein denotes CD4
T15495 4339-4344 Protein denotes STAT1
T15494 4325-4330 Protein denotes IL-10
T15493 4282-4285 Protein denotes CD4
T15492 4240-4245 Protein denotes STAT3
T15491 4226-4231 Protein denotes IL-10
T15490 4190-4195 Protein denotes STAT3
T15489 4168-4173 Protein denotes IL-10
T15488 4089-4094 Protein denotes STAT3
T15487 4033-4038 Protein denotes STAT3
T15486 3996-3999 Protein denotes CD4
T15485 3948-3953 Protein denotes STAT3
T15484 3908-3911 Protein denotes CD4
T15483 3870-3875 Protein denotes IL-10
T15482 3813-3818 Protein denotes STAT3
T15481 3713-3716 Protein denotes CD4
T15480 3701-3706 Protein denotes IL-10
T15479 3676-3681 Protein denotes STAT3
T15478 3666-3671 Protein denotes STAT1
T15477 3622-3627 Protein denotes STAT3
T15476 3487-3492 Protein denotes IL-10
T15475 3456-3461 Protein denotes STAT3
T15474 3417-3422 Protein denotes STAT3
T15473 3386-3391 Protein denotes STAT3
T15472 3376-3381 Protein denotes STAT1
T15471 3286-3291 Protein denotes IL-10
T15470 3274-3280 Protein denotes IL-10R
T15469 3242-3245 Protein denotes CD4
T15468 3214-3219 Protein denotes STAT3
T15467 3199-3204 Protein denotes IL-10
T14537 3161-3164 Protein denotes CD4
T14536 3149-3157 Negative_regulation denotes impaired
T14535 3136-3141 Protein denotes IL-10
T14534 3000-3009 Positive_regulation denotes increased
T14533 2969-2972 Protein denotes CD4
T14532 2955-2965 Gene_expression denotes expression
T14531 2947-2954 Protein denotes IL-10R1
T14530 2799-2802 Protein denotes CD4
T14529 2785-2792 Protein denotes IL-10R1
T14528 2771-2781 Gene_expression denotes expression
T14527 2701-2704 Protein denotes CD4
T14526 2684-2694 Negative_regulation denotes inhibition
T14525 2678-2683 Protein denotes IL-10
T14524 2629-2634 Protein denotes IL-10
T14523 2571-2581 Gene_expression denotes expression
T14522 2563-2570 Protein denotes IL-10R1
T14521 2544-2557 Protein denotes type 2 IL-10R
T14520 2508-2515 Protein denotes IL-10R1
T14519 2490-2497 Binding denotes binding
T14518 2439-2444 Protein denotes IL-10
T14517 2391-2394 Protein denotes CD4
T14516 2377-2384 Protein denotes IL-10R1
T14515 2350-2360 Gene_expression denotes expression
T14514 2340-2349 Positive_regulation denotes Increased
T14513 3161-3164 Protein denotes CD4
T14512 3136-3141 Protein denotes IL-10
T14511 2969-2972 Protein denotes CD4
T14510 2947-2954 Protein denotes IL-10R1
T14509 2799-2802 Protein denotes CD4
T14508 2785-2792 Protein denotes IL-10R1
T14507 2701-2704 Protein denotes CD4
T14506 2678-2683 Protein denotes IL-10
T14505 2629-2634 Protein denotes IL-10
T14504 2563-2570 Protein denotes IL-10R1
T14503 2544-2557 Protein denotes type 2 IL-10R
T14502 2508-2515 Protein denotes IL-10R1
T14501 2439-2444 Protein denotes IL-10
T14500 2391-2394 Protein denotes CD4
T14499 2377-2384 Protein denotes IL-10R1
T12304 2308-2313 Protein denotes IL-10
T12303 2298-2304 Regulation denotes effect
T12302 2237-2240 Protein denotes CD4
T12301 2136-2143 Negative_regulation denotes reduced
T12300 2084-2092 Negative_regulation denotes decrease
T12299 2051-2056 Protein denotes IL-10
T12298 2031-2039 Regulation denotes affected
T12297 2012-2022 Gene_expression denotes production
T12296 2007-2011 Protein denotes IL-2
T12295 1943-1948 Protein denotes IL-10
T12294 1905-1909 Protein denotes CD28
T12293 1878-1881 Protein denotes CD4
T12292 1864-1874 Gene_expression denotes production
T12291 1859-1863 Protein denotes IL-2
T12290 1810-1813 Protein denotes CD4
T12289 1788-1793 Protein denotes IL-10
T12288 1755-1760 Protein denotes IFN-γ
T12287 1729-1737 Gene_expression denotes produced
T12286 1692-1695 Protein denotes CD4
T12285 1447-1457 Gene_expression denotes production
T12284 1441-1446 Protein denotes IFN-γ
T12283 1432-1437 Protein denotes IL-10
T12282 1422-1428 Regulation denotes effect
T12281 1361-1366 Protein denotes IL-10
T12280 1342-1352 Gene_expression denotes production
T12279 1336-1341 Protein denotes IFN-γ
T12278 1101-1106 Protein denotes IL-10
T12277 1055-1059 Protein denotes CD28
T12276 1047-1050 Protein denotes CD3
T12275 1028-1031 Protein denotes CD4
T12274 1014-1024 Gene_expression denotes production
T12273 1008-1013 Protein denotes IFN-γ
T12272 941-946 Protein denotes IL-10
T12271 927-937 Negative_regulation denotes inhibition
T12270 887-892 Protein denotes IL-10
T12269 854-859 Protein denotes IFN-γ
T12268 823-830 Gene_expression denotes produce
T12267 797-800 Protein denotes CD4
T12266 778-783 Protein denotes IL-10
T12265 732-741 Negative_regulation denotes inhibited
T12264 708-711 Protein denotes CD4
T12263 677-687 Gene_expression denotes production
T12262 671-676 Protein denotes IFN-γ
T12261 617-627 Gene_expression denotes production
T12260 611-616 Protein denotes IFN-γ
T12259 587-592 Protein denotes IL-10
T12258 531-535 Protein denotes CD28
T12257 509-512 Protein denotes CD3
T12256 393-396 Protein denotes CD4
T12255 374-379 Protein denotes IL-10
T12254 358-361 Protein denotes CD4
T12253 274-281 Binding denotes binding
T12252 254-269 Phosphorylation denotes phosphorylation
T12251 240-244 Protein denotes CD28
T12250 229-239 Negative_regulation denotes inhibiting
T12249 184-189 Protein denotes IL-10
T12248 83-87 Protein denotes CD28
T12247 66-69 Protein denotes CD4
T12246 49-59 Gene_expression denotes production
T12245 43-48 Protein denotes IFN-γ
T12244 29-39 Negative_regulation denotes inhibition
T12243 23-28 Protein denotes IL-10
T12242 2308-2313 Protein denotes IL-10
T12241 2237-2240 Protein denotes CD4
T12240 2051-2056 Protein denotes IL-10
T12239 2007-2011 Protein denotes IL-2
T12238 1943-1948 Protein denotes IL-10
T12237 1905-1909 Protein denotes CD28
T12236 1878-1881 Protein denotes CD4
T12235 1859-1863 Protein denotes IL-2
T12234 1810-1813 Protein denotes CD4
T12233 1788-1793 Protein denotes IL-10
T12232 1755-1760 Protein denotes IFN-γ
T12231 1692-1695 Protein denotes CD4
T12230 1441-1446 Protein denotes IFN-γ
T12229 1432-1437 Protein denotes IL-10
T12228 1361-1366 Protein denotes IL-10
T12227 1336-1341 Protein denotes IFN-γ
T12226 1101-1106 Protein denotes IL-10
T12225 1055-1059 Protein denotes CD28
T12224 1047-1050 Protein denotes CD3
T12223 1028-1031 Protein denotes CD4
T12222 1008-1013 Protein denotes IFN-γ
T12221 941-946 Protein denotes IL-10
T12220 887-892 Protein denotes IL-10
T12219 854-859 Protein denotes IFN-γ
T12218 797-800 Protein denotes CD4
T12217 778-783 Protein denotes IL-10
T12216 708-711 Protein denotes CD4
T12215 671-676 Protein denotes IFN-γ
T12214 611-616 Protein denotes IFN-γ
T12213 587-592 Protein denotes IL-10
T12212 531-535 Protein denotes CD28
T12211 509-512 Protein denotes CD3
T12210 393-396 Protein denotes CD4
T12209 374-379 Protein denotes IL-10
T12208 358-361 Protein denotes CD4
T12207 240-244 Protein denotes CD28
T12206 184-189 Protein denotes IL-10
T12205 83-87 Protein denotes CD28
T12204 66-69 Protein denotes CD4
T12203 43-48 Protein denotes IFN-γ
T12202 23-28 Protein denotes IL-10
R7853 T15515 T15513 themeOf activation,induces
R7854 T15516 T15515 themeOf STAT1,activation
R7855 T15517 T15515 themeOf STAT3,activation
R7856 T15518 T15519 themeOf STAT3,deficient
R7857 T15522 T15523 themeOf STAT3,overexpression
R7858 T15525 T15527 themeOf STAT1,phosphorylation
R7859 T15526 T15527 themeOf STAT3,phosphorylation
R7860 T15527 T15524 themeOf phosphorylation,induction
R6330 T12243 T12244 causeOf IL-10,inhibition
R6331 T12245 T12246 themeOf IFN-γ,production
R6332 T12246 T12244 themeOf production,inhibition
R6333 T12249 T12250 causeOf IL-10,inhibiting
R6334 T12249 T12253 themeOf IL-10,binding
R6335 T12251 T12252 themeOf CD28,phosphorylation
R6336 T12252 T12250 themeOf phosphorylation,inhibiting
R6337 T12259 T12261 themeOf IL-10,production
R6338 T12260 T12261 themeOf IFN-γ,production
R6339 T12262 T12263 themeOf IFN-γ,production
R6340 T12263 T12265 themeOf production,inhibited
R6341 T12266 T12265 themeOf IL-10,inhibited
R6342 T12269 T12268 themeOf IFN-γ,produce
R6343 T12272 T12271 causeOf IL-10,inhibition
R6344 T12273 T12274 themeOf IFN-γ,production
R6345 T12279 T12280 themeOf IFN-γ,production
R6346 T12283 T12285 themeOf IL-10,production
R6347 T12284 T12285 themeOf IFN-γ,production
R6348 T12285 T12282 themeOf production,effect
R6349 T12288 T12287 themeOf IFN-γ,produced
R6350 T12291 T12292 themeOf IL-2,production
R6351 T12296 T12297 themeOf IL-2,production
R6352 T12297 T12300 themeOf production,decrease
R6353 T12297 T12301 themeOf production,reduced
R6354 T12297 T12298 themeOf production,affected
R6355 T12298 T12301 themeOf affected,reduced
R6356 T12299 T12298 causeOf IL-10,affected
R6357 T12300 T12298 causeOf decrease,affected
R6358 T12304 T12303 causeOf IL-10,effect
R7431 T14515 T14514 themeOf expression,Increased
R7432 T14516 T14515 themeOf IL-10R1,expression
R7433 T14520 T14519 themeOf IL-10R1,binding
R7434 T14521 T14519 themeOf type 2 IL-10R,binding
R7435 T14522 T14523 themeOf IL-10R1,expression
R7436 T14525 T14526 themeOf IL-10,inhibition
R7437 T14529 T14528 themeOf IL-10R1,expression
R7438 T14531 T14532 themeOf IL-10R1,expression
R7439 T14532 T14534 themeOf expression,increased
R7846 T15505 T15506 causeOf IL-10,mediated
R7847 T15506 T15504 themeOf mediated,Defective
R7848 T15507 T15508 themeOf STAT3,phosphorylation
R7849 T15508 T15506 themeOf phosphorylation,mediated
R7850 T15510 T15513 causeOf interaction,induces
R7851 T15511 T15510 themeOf IL-10R,interaction
R7852 T15514 T15513 themeOf phosphorylation,induces
R7861 T15528 T15524 causeOf IL-10,induction
R7862 T15530 T15531 themeOf STAT3,phosphorylation
R7863 T15531 T15532 themeOf phosphorylation,induced
R7864 T15533 T15534 themeOf IL-10,activation
R7865 T15534 T15532 causeOf activation,induced
R7866 T15536 T15537 themeOf STAT3,phosphorylated
R7867 T15539 T15540 themeOf STAT3,phosphorylation
R7868 T15541 T15542 themeOf STAT3,phosphorylation
R7869 T15542 T15544 themeOf phosphorylation,activated
R7870 T15542 T15543 themeOf phosphorylation,augmented
R7871 T15545 T15544 causeOf IL-10,activated
R7872 T15547 T15548 themeOf STAT3,phosphorylation
R7873 T15548 T15546 themeOf phosphorylation,sustained
R7874 T15550 T15551 causeOf IL-10,induced
R7875 T15551 T15549 themeOf induced,defective
R7876 T15552 T15553 themeOf STAT3,phosphorylation
R7877 T15553 T15551 themeOf phosphorylation,induced
R7878 T15555 T15556 causeOf IL-10,induced
R7879 T15557 T15558 themeOf STAT1,phosphorylation
R7880 T15558 T15556 themeOf phosphorylation,induced
R7881 T15562 T15563 themeOf IL-10,activated
R7882 T15565 T15566 causeOf IL-10,induced
R7883 T15566 T15569 themeOf induced,diminished
R7884 T15567 T15568 themeOf STAT3,activation
R7885 T15568 T15569 themeOf activation,diminished
R7886 T15568 T15566 themeOf activation,induced
R7887 T15572 T15573 themeOf STAT3,phosphorylation
R7888 T15573 T15571 themeOf phosphorylation,sustained
R8776 T17366 T17367 causeOf IL-6,mediated
R8777 T17368 T17369 themeOf STAT3,phosphorylation
R8778 T17369 T17367 themeOf phosphorylation,mediated
R8779 T17370 T17372 themeOf inhibition,effect
R8780 T17371 T17370 themeOf IL-10,inhibition
R8781 T17374 T17375 themeOf STAT3,activated
R8782 T17377 T17375 causeOf IL-11,activated
R8783 T17378 T17375 causeOf leukemia inhibitory factor,activated
R8784 T17379 T17375 causeOf oncostatin M,activated
R8785 T17379 T17384 causeOf oncostatin M,induces
R8786 T17380 T17375 causeOf platelet-derived growth factor,activated
R8787 T17381 T17384 causeOf epidermal growth factor,induces
R8788 T17381 T17375 causeOf epidermal growth factor,activated
R8789 T17382 T17375 causeOf IL-10,activated
R8790 T17383 T17384 causeOf IL-6,induces
R8791 T17385 T17384 themeOf activation,induces
R8792 T17386 T17385 themeOf STAT3,activation
R8793 T17390 T17391 themeOf STAT3,activation
R8794 T17392 T17393 themeOf IL-10,inhibition
R8795 T17394 T17396 themeOf STAT1,phosphorylation
R8796 T17395 T17396 themeOf STAT3,phosphorylation
R8797 T17396 T17397 themeOf phosphorylation,activated
R8798 T17398 T17397 causeOf IL-6,activated
R8799 T17403 T17409 themeOf induce,abolished
R8800 T17404 T17403 themeOf phosphorylation,induce
R8801 T17404 T17409 themeOf phosphorylation,abolished
R8802 T17405 T17404 themeOf STAT3,phosphorylation
R8803 T17406 T17404 themeOf STAT1,phosphorylation
R8804 T17407 T17408 themeOf STAT3,activation
R8805 T17408 T17409 themeOf activation,abolished
R8806 T17410 T17409 causeOf neutralization,abolished
R8807 T17411 T17410 themeOf IL-6,neutralization
R8808 T17415 T17416 themeOf STAT1,activation
R8809 T17416 T17414 themeOf activation,lack
R8810 T17419 T17420 themeOf STAT1,activation
R8811 T17420 T17418 themeOf activation,required
R8812 T17421 T17422 themeOf STAT3,activation
R8813 T17422 T17418 themeOf activation,required
R8814 T17425 T17429 causeOf IL-6,inhibit
R8815 T17425 T17426 causeOf IL-6,suppress
R8816 T17428 T17427 causeOf IL-10,effect
R8817 T17430 T17431 themeOf IFN-γ,production
R8818 T17431 T17429 themeOf production,inhibit
R8819 T17438 T17439 themeOf IFN-γ,production
R8820 T17442 T17444 causeOf IL-10,inhibition
R8821 T17442 T17443 causeOf IL-10,mediated
R8822 T17443 T17441 themeOf mediated,reduced
R8823 T17445 T17446 themeOf IFN-γ,production
R8824 T17446 T17444 themeOf production,inhibition
R8825 T17449 T17450 causeOf IL-6,role
R8826 T17452 T17453 themeOf STAT3,activation
R8827 T17453 T17451 themeOf activation,induction
R10115 T20096 T20095 themeOf expression,High
R10116 T20097 T20096 themeOf SOCS1,expression
R10117 T20099 T20100 causeOf IL-6,induces
R10118 T20101 T20100 themeOf inhibitors,induces
R10119 T20103 T20101 themeOf SOCS3,inhibitors
R10120 T20104 T20105 causeOf SOCS3,inhibit
R10121 T20104 T20111 causeOf SOCS3,regulating
R10122 T20106 T20107 themeOf STAT3,activation
R10123 T20107 T20108 themeOf activation,induced
R10124 T20107 T20105 themeOf activation,inhibit
R10125 T20108 T20105 themeOf induced,inhibit
R10126 T20109 T20108 causeOf IL-6,induced
R10127 T20110 T20108 causeOf IL-10,induced
R10128 T20114 T20115 causeOf SOCS1,inhibit
R10129 T20116 T20117 causeOf IL-10,mediated
R10130 T20117 T20115 themeOf mediated,inhibit
R10131 T20118 T20119 themeOf STAT3,activation
R10132 T20119 T20117 themeOf activation,mediated
R10133 T20120 T20121 causeOf IFN-γ,mediated
R10134 T20122 T20123 themeOf STAT1,activation
R10135 T20123 T20121 themeOf activation,mediated
R10136 T20124 T20125 causeOf IL-10,induced
R10137 T20126 T20127 themeOf STAT3,activation
R10138 T20127 T20125 themeOf activation,induced
R10139 T20129 T20131 themeOf SOCS1,mRNA expression
R10140 T20130 T20131 themeOf SOCS3,mRNA expression
R10141 T20138 T20137 themeOf SOCS1,expression
R10142 T20144 T20145 causeOf IL-10,induced
R10143 T20145 T20148 themeOf induced,due
R10144 T20145 T20143 themeOf induced,Defective
R10145 T20146 T20147 themeOf STAT3,activation
R10146 T20147 T20145 themeOf activation,induced
R10147 T20147 T20148 themeOf activation,due
R10148 T20149 T20148 causeOf SOCS1,due

testone

Id Subject Object Predicate Lexical cue
T20027 8331-8341 Positive_regulation denotes activation
T20026 8317-8324 Positive_regulation denotes induced
T20025 8301-8310 Negative_regulation denotes Defective
T20024 8188-8198 Gene_expression denotes expression
T20023 8120-8130 Gene_expression denotes expression
T20022 7841-7856 Transcription denotes mRNA expression
T20021 7780-7790 Positive_regulation denotes activation
T20020 7766-7773 Positive_regulation denotes induced
T20019 7750-7759 Negative_regulation denotes defective
T20018 7618-7628 Positive_regulation denotes activation
T20017 7603-7611 Positive_regulation denotes mediated
T20016 7589-7596 Negative_regulation denotes inhibit
T20015 7488-7498 Regulation denotes regulating
T20014 7446-7453 Positive_regulation denotes induced
T20013 7435-7445 Positive_regulation denotes activation
T20012 7421-7428 Negative_regulation denotes inhibit
T20011 7163-7173 Negative_regulation denotes inhibitors
T20010 7144-7151 Positive_regulation denotes induces
T20009 7095-7105 Gene_expression denotes expression
T20008 7090-7094 Positive_regulation denotes High
T20007 8418-8421 Protein denotes CD4
T20006 8406-8411 Protein denotes SOCS1
T20005 8325-8330 Protein denotes STAT3
T20004 8311-8316 Protein denotes IL-10
T20003 8245-8249 Protein denotes IL-6
T20002 8209-8212 Protein denotes CD4
T20001 8151-8154 Protein denotes CD4
T20000 8134-8139 Protein denotes SOCS1
T19999 8083-8086 Protein denotes CD4
T19998 8048-8053 Protein denotes SOCS3
T19997 8022-8027 Protein denotes SOCS1
T19996 7982-7985 Protein denotes CD4
T19995 7863-7866 Protein denotes CD4
T19994 7835-7840 Protein denotes SOCS3
T19993 7825-7830 Protein denotes SOCS1
T19992 7797-7800 Protein denotes CD4
T19991 7774-7779 Protein denotes STAT3
T19990 7760-7765 Protein denotes IL-10
T19989 7679-7684 Protein denotes STAT1
T19988 7664-7669 Protein denotes IFN-γ
T19987 7612-7617 Protein denotes STAT3
T19986 7597-7602 Protein denotes IL-10
T19985 7562-7567 Protein denotes SOCS1
T19984 7532-7537 Protein denotes IL-10
T19983 7523-7527 Protein denotes IL-6
T19982 7473-7478 Protein denotes IL-10
T19981 7457-7461 Protein denotes IL-6
T19980 7429-7434 Protein denotes STAT3
T19979 7375-7380 Protein denotes SOCS3
T19978 7193-7198 Protein denotes SOCS3
T19977 7183-7188 Protein denotes SOCS1
T19976 7139-7143 Protein denotes IL-6
T19975 7126-7129 Protein denotes CD4
T19974 7109-7114 Protein denotes SOCS1
T17264 7042-7059 Negative_regulation denotes inhibitory effect
T17263 7005-7015 Positive_regulation denotes activation
T17262 6986-6995 Positive_regulation denotes induction
T17261 6969-6973 Regulation denotes role
T17260 6767-6777 Gene_expression denotes production
T17259 6747-6757 Negative_regulation denotes inhibition
T17258 6738-6746 Positive_regulation denotes mediated
T17257 6724-6731 Negative_regulation denotes reduced
T17256 6656-6666 Gene_expression denotes production
T17255 6412-6419 Negative_regulation denotes inhibit
T17254 6393-6399 Regulation denotes effect
T17253 6380-6388 Negative_regulation denotes suppress
T17252 6266-6276 Positive_regulation denotes activation
T17251 6213-6221 Positive_regulation denotes required
T17250 5959-5973 Negative_regulation denotes neutralization
T17249 5946-5955 Negative_regulation denotes abolished
T17248 5924-5934 Positive_regulation denotes activation
T17247 5869-5884 Phosphorylation denotes phosphorylation
T17246 5853-5859 Positive_regulation denotes induce
T17245 5777-5792 Phosphorylation denotes phosphorylation
T17244 5491-5500 Positive_regulation denotes activated
T17243 5471-5486 Phosphorylation denotes phosphorylation
T17242 5425-5435 Negative_regulation denotes inhibition
T17241 5390-5400 Positive_regulation denotes activation
T17240 5352-5363 Positive_regulation denotes responsible
T17239 5091-5101 Positive_regulation denotes activation
T17238 5070-5077 Positive_regulation denotes induces
T17237 4743-4752 Positive_regulation denotes activated
T17236 4704-4710 Regulation denotes effect
T17235 4684-4694 Negative_regulation denotes inhibition
T17234 4664-4679 Phosphorylation denotes phosphorylation
T17233 4649-4657 Positive_regulation denotes mediated
T17232 7075-7078 Protein denotes CD4
T17231 7063-7068 Protein denotes IL-10
T17230 6999-7004 Protein denotes STAT3
T17229 6953-6957 Protein denotes IL-6
T17228 6873-6878 Protein denotes IL-10
T17227 6828-6832 Protein denotes IL-6
T17226 6761-6766 Protein denotes IFN-γ
T17225 6732-6737 Protein denotes IL-10
T17224 6690-6694 Protein denotes IL-6
T17223 6650-6655 Protein denotes IFN-γ
T17222 6622-6627 Protein denotes IL-10
T17221 6565-6569 Protein denotes CD28
T17220 6525-6528 Protein denotes CD4
T17219 6499-6503 Protein denotes IL-6
T17218 6440-6443 Protein denotes CD4
T17217 6420-6425 Protein denotes IFN-γ
T17216 6403-6408 Protein denotes IL-10
T17215 6369-6373 Protein denotes IL-6
T17214 6300-6305 Protein denotes STAT1
T17213 6260-6265 Protein denotes STAT3
T17212 6226-6231 Protein denotes STAT1
T17211 6201-6205 Protein denotes IL-6
T17210 6128-6133 Protein denotes STAT1
T17209 6051-6056 Protein denotes STAT3
T17208 6030-6034 Protein denotes IL-6
T17207 5977-5981 Protein denotes IL-6
T17206 5918-5923 Protein denotes STAT3
T17205 5902-5907 Protein denotes STAT1
T17204 5888-5893 Protein denotes STAT3
T17203 5733-5737 Protein denotes IL-6
T17202 5602-5605 Protein denotes CD4
T17201 5519-5522 Protein denotes CD4
T17200 5504-5508 Protein denotes IL-6
T17199 5465-5470 Protein denotes STAT3
T17198 5455-5460 Protein denotes STAT1
T17197 5419-5424 Protein denotes IL-10
T17196 5384-5389 Protein denotes STAT3
T17195 5318-5322 Protein denotes IL-6
T17194 5279-5282 Protein denotes CD4
T17193 5144-5148 Protein denotes IL-6
T17192 5105-5110 Protein denotes STAT3
T17191 5019-5023 Protein denotes IL-6
T17190 4964-4969 Protein denotes IL-10
T17189 4924-4947 Protein denotes epidermal growth factor
T17188 4888-4918 Protein denotes platelet-derived growth factor
T17187 4873-4885 Protein denotes oncostatin M
T17186 4841-4867 Protein denotes leukemia inhibitory factor
T17185 4834-4839 Protein denotes IL-11
T17184 4828-4832 Protein denotes IL-6
T17183 4734-4739 Protein denotes STAT3
T17182 4721-4724 Protein denotes CD4
T17181 4698-4703 Protein denotes IL-10
T17180 4658-4663 Protein denotes STAT3
T17179 4644-4648 Protein denotes IL-6
T17178 6426-6436 Gene_expression denotes production
T15433 4626-4641 Phosphorylation denotes phosphorylation
T15432 4610-4619 Positive_regulation denotes sustained
T15431 4593-4604 Binding denotes association
T15430 4579-4585 Positive_regulation denotes active
T15429 4565-4575 Negative_regulation denotes diminished
T15428 4547-4557 Positive_regulation denotes activation
T15427 4533-4540 Positive_regulation denotes induced
T15426 4491-4500 Positive_regulation denotes activated
T15425 4345-4360 Phosphorylation denotes phosphorylation
T15424 4331-4338 Positive_regulation denotes induced
T15423 4246-4261 Phosphorylation denotes phosphorylation
T15422 4232-4239 Positive_regulation denotes induced
T15421 4216-4225 Negative_regulation denotes defective
T15420 4196-4211 Phosphorylation denotes phosphorylation
T15419 4180-4189 Positive_regulation denotes sustained
T15418 4135-4144 Positive_regulation denotes activated
T15417 4115-4124 Positive_regulation denotes augmented
T15416 4095-4110 Phosphorylation denotes phosphorylation
T15415 4039-4054 Phosphorylation denotes phosphorylation
T15414 3958-3972 Phosphorylation denotes phosphorylated
T15413 3876-3886 Positive_regulation denotes activation
T15412 3856-3863 Positive_regulation denotes induced
T15411 3819-3834 Phosphorylation denotes phosphorylation
T15410 3682-3697 Phosphorylation denotes phosphorylation
T15409 3653-3662 Positive_regulation denotes induction
T15408 3628-3642 Positive_regulation denotes overexpression
T15407 3423-3432 Negative_regulation denotes deficient
T15406 3329-3339 Positive_regulation denotes activation
T15405 3309-3324 Phosphorylation denotes phosphorylation
T15404 3292-3299 Positive_regulation denotes induces
T15403 3259-3270 Binding denotes interaction
T15402 3220-3235 Phosphorylation denotes phosphorylation
T15401 3205-3213 Positive_regulation denotes mediated
T15400 3189-3198 Negative_regulation denotes Defective
T15399 4620-4625 Protein denotes STAT3
T15398 4541-4546 Protein denotes STAT3
T15397 4527-4532 Protein denotes IL-10
T15396 4509-4512 Protein denotes CD4
T15395 4485-4490 Protein denotes IL-10
T15394 4466-4471 Protein denotes STAT3
T15393 4414-4417 Protein denotes CD4
T15392 4391-4394 Protein denotes CD4
T15391 4339-4344 Protein denotes STAT1
T15390 4325-4330 Protein denotes IL-10
T15389 4282-4285 Protein denotes CD4
T15388 4240-4245 Protein denotes STAT3
T15387 4226-4231 Protein denotes IL-10
T15386 4190-4195 Protein denotes STAT3
T15385 4168-4173 Protein denotes IL-10
T15384 4089-4094 Protein denotes STAT3
T15383 4033-4038 Protein denotes STAT3
T15382 3996-3999 Protein denotes CD4
T15381 3948-3953 Protein denotes STAT3
T15380 3908-3911 Protein denotes CD4
T15379 3870-3875 Protein denotes IL-10
T15378 3813-3818 Protein denotes STAT3
T15377 3713-3716 Protein denotes CD4
T15376 3701-3706 Protein denotes IL-10
T15375 3676-3681 Protein denotes STAT3
T15374 3666-3671 Protein denotes STAT1
T15373 3622-3627 Protein denotes STAT3
T15372 3487-3492 Protein denotes IL-10
T15371 3456-3461 Protein denotes STAT3
T15370 3417-3422 Protein denotes STAT3
T15369 3386-3391 Protein denotes STAT3
T15368 3376-3381 Protein denotes STAT1
T15367 3286-3291 Protein denotes IL-10
T15366 3274-3280 Protein denotes IL-10R
T15365 3242-3245 Protein denotes CD4
T15364 3214-3219 Protein denotes STAT3
T15363 3199-3204 Protein denotes IL-10
T14469 2678-2683 Protein denotes IL-10
T14468 2629-2634 Protein denotes IL-10
T14467 2563-2570 Protein denotes IL-10R1
T14466 2544-2557 Protein denotes type 2 IL-10R
T14465 2508-2515 Protein denotes IL-10R1
T14464 2439-2444 Protein denotes IL-10
T14463 2391-2394 Protein denotes CD4
T14462 2377-2384 Protein denotes IL-10R1
T14486 3149-3157 Negative_regulation denotes impaired
T14485 3000-3009 Positive_regulation denotes increased
T14484 2955-2965 Gene_expression denotes expression
T14483 2771-2781 Gene_expression denotes expression
T14482 2742-2752 Gene_expression denotes expression
T14481 2684-2694 Negative_regulation denotes inhibition
T14480 2571-2581 Gene_expression denotes expression
T14479 2490-2497 Binding denotes binding
T14478 2350-2360 Gene_expression denotes expression
T14477 2340-2349 Positive_regulation denotes Increased
T14476 3161-3164 Protein denotes CD4
T14475 3136-3141 Protein denotes IL-10
T14474 2969-2972 Protein denotes CD4
T14473 2947-2954 Protein denotes IL-10R1
T14472 2799-2802 Protein denotes CD4
T14471 2785-2792 Protein denotes IL-10R1
T14470 2701-2704 Protein denotes CD4
T12174 2298-2304 Regulation denotes effect
T12173 2136-2143 Negative_regulation denotes reduced
T12172 2084-2092 Negative_regulation denotes decrease
T12171 2031-2039 Regulation denotes affected
T12170 2012-2022 Gene_expression denotes production
T12169 1864-1874 Gene_expression denotes production
T12168 1738-1744 Positive_regulation denotes higher
T12167 1729-1737 Gene_expression denotes produced
T12166 1476-1483 Negative_regulation denotes limited
T12165 1447-1457 Gene_expression denotes production
T12164 1422-1428 Regulation denotes effect
T12163 1411-1421 Negative_regulation denotes inhibitory
T12162 1342-1352 Gene_expression denotes production
T12161 1014-1024 Gene_expression denotes production
T12160 927-937 Negative_regulation denotes inhibition
T12159 823-830 Gene_expression denotes produce
T12158 732-741 Negative_regulation denotes inhibited
T12157 677-687 Gene_expression denotes production
T12156 617-627 Gene_expression denotes production
T12155 49-59 Gene_expression denotes production
T12154 29-39 Negative_regulation denotes inhibition
T12153 2308-2313 Protein denotes IL-10
T12152 2237-2240 Protein denotes CD4
T12151 2051-2056 Protein denotes IL-10
T12150 2007-2011 Protein denotes IL-2
T12149 1943-1948 Protein denotes IL-10
T12148 1905-1909 Protein denotes CD28
T12147 1878-1881 Protein denotes CD4
T12146 1859-1863 Protein denotes IL-2
T12145 1810-1813 Protein denotes CD4
T12144 1788-1793 Protein denotes IL-10
T12143 1755-1760 Protein denotes IFN-γ
T12142 1692-1695 Protein denotes CD4
T12141 1441-1446 Protein denotes IFN-γ
T12140 1432-1437 Protein denotes IL-10
T12139 1361-1366 Protein denotes IL-10
T12138 1336-1341 Protein denotes IFN-γ
T12137 1101-1106 Protein denotes IL-10
T12136 1055-1059 Protein denotes CD28
T12135 1047-1050 Protein denotes CD3
T12134 1028-1031 Protein denotes CD4
T12133 1008-1013 Protein denotes IFN-γ
T12132 941-946 Protein denotes IL-10
T12131 887-892 Protein denotes IL-10
T12130 854-859 Protein denotes IFN-γ
T12129 797-800 Protein denotes CD4
T12128 778-783 Protein denotes IL-10
T12127 708-711 Protein denotes CD4
T12126 671-676 Protein denotes IFN-γ
T12125 611-616 Protein denotes IFN-γ
T12124 587-592 Protein denotes IL-10
T12123 531-535 Protein denotes CD28
T12122 509-512 Protein denotes CD3
T12121 393-396 Protein denotes CD4
T12120 374-379 Protein denotes IL-10
T12119 358-361 Protein denotes CD4
T12118 240-244 Protein denotes CD28
T12117 184-189 Protein denotes IL-10
T12116 83-87 Protein denotes CD28
T12115 66-69 Protein denotes CD4
T12114 43-48 Protein denotes IFN-γ
T12113 23-28 Protein denotes IL-10
R6304 T12113 T12154 causeOf IL-10,inhibition
R6305 T12114 T12155 themeOf IFN-γ,production
R6306 T12124 T12156 themeOf IL-10,production
R6307 T12125 T12156 themeOf IFN-γ,production
R6308 T12126 T12157 themeOf IFN-γ,production
R6309 T12130 T12159 themeOf IFN-γ,produce
R6310 T12132 T12160 causeOf IL-10,inhibition
R6311 T12133 T12161 themeOf IFN-γ,production
R6312 T12138 T12162 themeOf IFN-γ,production
R6313 T12141 T12165 themeOf IFN-γ,production
R6314 T12143 T12167 themeOf IFN-γ,produced
R6315 T12143 T12168 themeOf IFN-γ,higher
R6316 T12144 T12168 causeOf IL-10,higher
R6317 T12146 T12169 themeOf IL-2,production
R6318 T12150 T12170 themeOf IL-2,production
R6319 T12151 T12171 causeOf IL-10,affected
R6320 T12153 T12174 themeOf IL-10,effect
R6321 T12155 T12154 themeOf production,inhibition
R6322 T12157 T12158 themeOf production,inhibited
R6323 T12165 T12166 themeOf production,limited
R6324 T12165 T12164 themeOf production,effect
R6325 T12167 T12168 themeOf produced,higher
R6326 T12170 T12172 themeOf production,decrease
R6327 T12170 T12173 themeOf production,reduced
R6328 T12170 T12171 themeOf production,affected
R6329 T12172 T12171 causeOf decrease,affected
R7424 T14462 T14478 themeOf IL-10R1,expression
R7425 T14467 T14480 themeOf IL-10R1,expression
R7426 T14469 T14481 themeOf IL-10,inhibition
R7427 T14471 T14482 themeOf IL-10R1,expression
R7428 T14471 T14483 themeOf IL-10R1,expression
R7429 T14473 T14484 themeOf IL-10R1,expression
R7430 T14484 T14485 themeOf expression,increased
R7800 T15363 T15400 causeOf IL-10,Defective
R7801 T15363 T15401 causeOf IL-10,mediated
R7802 T15364 T15402 themeOf STAT3,phosphorylation
R7803 T15366 T15403 themeOf IL-10R,interaction
R7804 T15367 T15403 themeOf IL-10,interaction
R7805 T15368 T15406 themeOf STAT1,activation
R7806 T15369 T15406 themeOf STAT3,activation
R7807 T15370 T15407 themeOf STAT3,deficient
R7808 T15373 T15408 themeOf STAT3,overexpression
R7809 T15374 T15410 themeOf STAT1,phosphorylation
R7810 T15375 T15410 themeOf STAT3,phosphorylation
R7811 T15376 T15409 causeOf IL-10,induction
R7812 T15378 T15411 themeOf STAT3,phosphorylation
R7813 T15379 T15412 causeOf IL-10,induced
R7814 T15381 T15414 themeOf STAT3,phosphorylated
R7815 T15383 T15415 themeOf STAT3,phosphorylation
R7816 T15384 T15416 themeOf STAT3,phosphorylation
R7817 T15385 T15417 causeOf IL-10,augmented
R7818 T15385 T15418 causeOf IL-10,activated
R7819 T15386 T15420 themeOf STAT3,phosphorylation
R7820 T15387 T15422 causeOf IL-10,induced
R7821 T15388 T15423 themeOf STAT3,phosphorylation
R7822 T15390 T15424 causeOf IL-10,induced
R7823 T15391 T15425 themeOf STAT1,phosphorylation
R7824 T15395 T15426 themeOf IL-10,activated
R7825 T15397 T15427 causeOf IL-10,induced
R7826 T15398 T15428 themeOf STAT3,activation
R7827 T15399 T15433 themeOf STAT3,phosphorylation
R7828 T15401 T15400 themeOf mediated,Defective
R7829 T15402 T15401 themeOf phosphorylation,mediated
R7830 T15403 T15404 causeOf interaction,induces
R7831 T15405 T15404 themeOf phosphorylation,induces
R7832 T15406 T15404 themeOf activation,induces
R7833 T15410 T15409 themeOf phosphorylation,induction
R7834 T15411 T15412 themeOf phosphorylation,induced
R7835 T15413 T15412 causeOf activation,induced
R7836 T15416 T15417 themeOf phosphorylation,augmented
R7837 T15420 T15419 themeOf phosphorylation,sustained
R7838 T15422 T15421 themeOf induced,defective
R7839 T15423 T15422 themeOf phosphorylation,induced
R7840 T15425 T15424 themeOf phosphorylation,induced
R7841 T15428 T15427 themeOf activation,induced
R7842 T15430 T15429 themeOf active,diminished
R7843 T15431 T15429 themeOf association,diminished
R7844 T15432 T15430 themeOf sustained,active
R7845 T15433 T15432 themeOf phosphorylation,sustained
R8725 T17178 T17255 themeOf production,inhibit
R8726 T17179 T17233 causeOf IL-6,mediated
R8727 T17180 T17234 themeOf STAT3,phosphorylation
R8728 T17181 T17235 themeOf IL-10,inhibition
R8729 T17183 T17237 themeOf STAT3,activated
R8730 T17185 T17237 causeOf IL-11,activated
R8731 T17186 T17237 causeOf leukemia inhibitory factor,activated
R8732 T17187 T17237 causeOf oncostatin M,activated
R8733 T17188 T17237 causeOf platelet-derived growth factor,activated
R8734 T17189 T17238 causeOf epidermal growth factor,induces
R8735 T17189 T17237 causeOf epidermal growth factor,activated
R8736 T17190 T17237 causeOf IL-10,activated
R8737 T17191 T17238 causeOf IL-6,induces
R8738 T17191 T17237 causeOf IL-6,activated
R8739 T17192 T17239 themeOf STAT3,activation
R8740 T17196 T17241 themeOf STAT3,activation
R8741 T17197 T17242 themeOf IL-10,inhibition
R8742 T17198 T17243 themeOf STAT1,phosphorylation
R8743 T17199 T17243 themeOf STAT3,phosphorylation
R8744 T17200 T17244 causeOf IL-6,activated
R8745 T17204 T17247 themeOf STAT3,phosphorylation
R8746 T17205 T17247 themeOf STAT1,phosphorylation
R8747 T17206 T17248 themeOf STAT3,activation
R8748 T17207 T17250 themeOf IL-6,neutralization
R8749 T17213 T17252 themeOf STAT3,activation
R8750 T17215 T17255 causeOf IL-6,inhibit
R8751 T17215 T17253 causeOf IL-6,suppress
R8752 T17216 T17255 causeOf IL-10,inhibit
R8753 T17217 T17178 themeOf IFN-γ,production
R8754 T17223 T17256 themeOf IFN-γ,production
R8755 T17225 T17258 causeOf IL-10,mediated
R8756 T17226 T17260 themeOf IFN-γ,production
R8757 T17229 T17261 causeOf IL-6,role
R8758 T17230 T17263 themeOf STAT3,activation
R8759 T17231 T17264 themeOf IL-10,inhibitory effect
R8760 T17234 T17233 themeOf phosphorylation,mediated
R8761 T17239 T17238 themeOf activation,induces
R8762 T17241 T17240 themeOf activation,responsible
R8763 T17242 T17240 themeOf inhibition,responsible
R8764 T17243 T17244 themeOf phosphorylation,activated
R8765 T17246 T17249 themeOf induce,abolished
R8766 T17247 T17246 themeOf phosphorylation,induce
R8767 T17248 T17249 themeOf activation,abolished
R8768 T17250 T17249 causeOf neutralization,abolished
R8769 T17252 T17251 themeOf activation,required
R8770 T17258 T17257 themeOf mediated,reduced
R8771 T17259 T17257 themeOf inhibition,reduced
R8772 T17259 T17258 themeOf inhibition,mediated
R8773 T17260 T17259 themeOf production,inhibition
R8774 T17262 T17261 themeOf induction,role
R8775 T17263 T17262 themeOf activation,induction
R10083 T19974 T20009 themeOf SOCS1,expression
R10084 T19976 T20010 causeOf IL-6,induces
R10085 T19978 T20011 themeOf SOCS3,inhibitors
R10086 T19979 T20012 causeOf SOCS3,inhibit
R10087 T19979 T20015 causeOf SOCS3,regulating
R10088 T19980 T20013 themeOf STAT3,activation
R10089 T19981 T20014 causeOf IL-6,induced
R10090 T19981 T20012 causeOf IL-6,inhibit
R10091 T19982 T20014 causeOf IL-10,induced
R10092 T19982 T20012 causeOf IL-10,inhibit
R10093 T19985 T20016 causeOf SOCS1,inhibit
R10094 T19986 T20017 causeOf IL-10,mediated
R10095 T19987 T20018 themeOf STAT3,activation
R10096 T19990 T20020 causeOf IL-10,induced
R10097 T19991 T20021 themeOf STAT3,activation
R10098 T19993 T20022 themeOf SOCS1,mRNA expression
R10099 T19994 T20022 themeOf SOCS3,mRNA expression
R10100 T20000 T20023 themeOf SOCS1,expression
R10101 T20004 T20025 causeOf IL-10,Defective
R10102 T20004 T20026 causeOf IL-10,induced
R10103 T20005 T20027 themeOf STAT3,activation
R10104 T20009 T20008 themeOf expression,High
R10105 T20013 T20014 themeOf activation,induced
R10106 T20013 T20012 themeOf activation,inhibit
R10107 T20014 T20012 themeOf induced,inhibit
R10108 T20017 T20016 themeOf mediated,inhibit
R10109 T20018 T20017 themeOf activation,mediated
R10110 T20020 T20019 themeOf induced,defective
R10111 T20021 T20020 themeOf activation,induced
R10112 T20022 T20020 themeOf mRNA expression,induced
R10113 T20026 T20025 themeOf induced,Defective
R10114 T20027 T20026 themeOf activation,induced