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inhibition of interferon gamma production and expression of suppressor of cytokine signaling 1 in CD4+ T cells from patients with rheumatoid arthritis\n\nAbstract\nIL-10 has been shown to block the antigen-specific T-cell cytokine response by inhibiting the CD28 signaling pathway. We found that peripheral blood CD4+ T cells from patients with active rheumatoid arthritis (RA) were able to produce greater amounts of interferon gamma after CD3 and CD28 costimulation in the presence of 1 ng/ml IL-10 than were normal control CD4+ T cells, although their surface expression of the type 1 IL-10 receptor was increased. The phosphorylation of signal transducer and activator of transcription 3 was sustained in both blood and s"}

    bionlp-st-ge-2016-test-proteins

    {"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T967","span":{"begin":0,"end":5},"obj":"Protein"},{"id":"T968","span":{"begin":20,"end":36},"obj":"Protein"},{"id":"T969","span":{"begin":66,"end":100},"obj":"Protein"},{"id":"T970","span":{"begin":104,"end":107},"obj":"Protein"},{"id":"T971","span":{"begin":167,"end":172},"obj":"Protein"},{"id":"T972","span":{"begin":261,"end":265},"obj":"Protein"},{"id":"T973","span":{"begin":316,"end":319},"obj":"Protein"},{"id":"T974","span":{"begin":421,"end":437},"obj":"Protein"},{"id":"T975","span":{"begin":452,"end":456},"obj":"Protein"},{"id":"T976","span":{"begin":498,"end":503},"obj":"Protein"},{"id":"T977","span":{"begin":529,"end":532},"obj":"Protein"},{"id":"T978","span":{"begin":584,"end":605},"obj":"Protein"},{"id":"T979","span":{"begin":644,"end":694},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"IL-10 inhibition of interferon gamma production and expression of suppressor of cytokine signaling 1 in CD4+ T cells from patients with rheumatoid arthritis\n\nAbstract\nIL-10 has been shown to block the antigen-specific T-cell cytokine response by inhibiting the CD28 signaling pathway. We found that peripheral blood CD4+ T cells from patients with active rheumatoid arthritis (RA) were able to produce greater amounts of interferon gamma after CD3 and CD28 costimulation in the presence of 1 ng/ml IL-10 than were normal control CD4+ T cells, although their surface expression of the type 1 IL-10 receptor was increased. The phosphorylation of signal transducer and activator of transcription 3 was sustained in both blood and s"}

    bionlp-st-ge-2016-uniprot

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    UBERON-AE

    {"project":"UBERON-AE","denotations":[{"id":"T435","span":{"begin":717,"end":722},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T434","span":{"begin":310,"end":315},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"IL-10 inhibition of interferon gamma production and expression of suppressor of cytokine signaling 1 in CD4+ T cells from patients with rheumatoid arthritis\n\nAbstract\nIL-10 has been shown to block the antigen-specific T-cell cytokine response by inhibiting the CD28 signaling pathway. We found that peripheral blood CD4+ T cells from patients with active rheumatoid arthritis (RA) were able to produce greater amounts of interferon gamma after CD3 and CD28 costimulation in the presence of 1 ng/ml IL-10 than were normal control CD4+ T cells, although their surface expression of the type 1 IL-10 receptor was increased. The phosphorylation of signal transducer and activator of transcription 3 was sustained in both blood and s"}

    GO-BP

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    GO-CC

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    GO-MF

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    sentences

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    ICD10

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    simple1

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    BioNLP16_DUT

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    BioNLP16_Messiy

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    DLUT931

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    bionlp-st-ge-2016-test-ihmc

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    bionlp-st-ge-2016-spacy-parsed

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