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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1044830","sourcedb":"PMC","sourceid":"1044830","source_url":"https://www.ncbi.nlm.nih.gov/pmc/1044830","text":"Sex differences in recombination were discovered in the first linkage studies on Drosophila [1,2] and Bombyx (Tanaka [1914] in [3]) almost one century ago. However, this observation remains today largely unexplained despite several attempts. Based on very limited observations (see Table 1), especially of Bombyx, in which the female is heterogametic, Haldane [3] suggested, as far as “these facts are anything more than a coincidence,” that the lower autosomal recombination rate in the heterogametic sex may reflect a pleiotropic consequence of selection against recombination between the sex chromosomes. Later, Huxley [4] showed that Gammarus males also recombined less than females. He gave the same evolutionary explanation, although he restricted it to cases of a marked sex difference.","tracks":[]}