PMC:103662 / 3415-4023 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/103662","sourcedb":"PMC","sourceid":"103662","source_url":"https://www.ncbi.nlm.nih.gov/pmc/103662","text":"Like bR, pR consists of seven transmembrane α-helices that include in the membrane interior all of the residues conserved among archaeal rhodopsin proton pumps. In particular, analogues of Asp-85, Asp96, Arg-82, and Lys-216 of bR are present in pR. Conspicuously absent are analogues for Glu-194 and Glu-204 of bR. The latter, as well as Arg-82, have been implicated in fast proton release. In particular, mutagenesis of Glu-194 or Glu-204 in bR results in loss of fast proton release [3,4]. The absence of homologs for these residues in pR leaves open the question of whether it carries out fast H+ release.","tracks":[]}