OMIM_GOF@xiajingbo:104760-12-APP JSONTXT

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AGAC-2-2

Id Subject Object Predicate Lexical cue
T1 142-176 Var denotes val715-to-met (V715M) substitution
T10 358-372 Var denotes V715M mutation
T11 387-394 NegReg denotes reduced
T12 395-414 MPA denotes A-beta-40 secretion
T13 489-497 PosReg denotes increase
T14 501-552 MPA denotes N-terminally truncated A-beta ending at position 42
T15 713-722 NegReg denotes reduction
T16 738-758 MPA denotes production of A-beta
T17 781-790 PosReg denotes increased
T18 791-852 MPA denotes production of truncated forms of A-beta ending at position 42
T2 101-109 Var denotes mutation
T3 117-120 Gene denotes APP
T4 127-139 Reg denotes resulting in
T5 196-201 Var denotes V715M
T6 243-250 NegReg denotes reduced
T7 257-274 MPA denotes A-beta production
T8 279-288 PosReg denotes increased
T9 293-352 MPA denotes recovery of the physiologically secreted product, APP-alpha
R8 T10 T11 CauseOf V715M mutation,reduced
R9 T12 T11 ThemeOf A-beta-40 secretion,reduced
R1 T3 T2 ThemeOf APP,mutation
R11 T14 T13 ThemeOf N-terminally truncated A-beta ending at position 42,increase
R12 T16 T15 ThemeOf production of A-beta,reduction
R13 T18 T17 ThemeOf production of truncated forms of A-beta ending at position 42,increased
R2 T2 T4 CauseOf mutation,resulting in
R3 T1 T4 ThemeOf val715-to-met (V715M) substitution,resulting in
R4 T5 T6 CauseOf V715M,reduced
R5 T7 T6 ThemeOf A-beta production,reduced
R6 T5 T8 CauseOf V715M,increased
R7 T9 T8 ThemeOf "recovery of the physiologically secreted product, APP-alpha",increased

AGAC-2-1

Id Subject Object Predicate Lexical cue
T1 142-176 Var denotes val715-to-met (V715M) substitution
T2 117-120 Gene denotes APP
T3 127-139 Reg denotes resulting in
T4 101-109 Var denotes mutation
T5 196-201 Var denotes V715M
T6 178-192 PosReg denotes Overexpression
T7 243-250 NegReg denotes reduced
T8 257-274 MPA denotes A-beta production
T9 279-288 PosReg denotes increased
T10 293-341 MPA denotes recovery of the physiologically secreted product
T11 358-372 Var denotes V715M mutation
T12 387-394 NegReg denotes reduced
T13 395-414 MPA denotes A-beta-40 secretion
T14 489-497 PosReg denotes increase
T15 501-530 MPA denotes N-terminally truncated A-beta
R1 T2 T4 ThemeOf APP,mutation
R2 T4 T3 CauseOf mutation,resulting in
R3 T1 T3 ThemeOf val715-to-met (V715M) substitution,resulting in
R4 T5 T6 ThemeOf V715M,Overexpression
R5 T6 T7 CauseOf Overexpression,reduced
R6 T8 T7 ThemeOf A-beta production,reduced
R7 T6 T9 CauseOf Overexpression,increased
R8 T10 T9 ThemeOf recovery of the physiologically secreted product,increased
R9 T11 T12 CauseOf V715M mutation,reduced
R10 T13 T12 ThemeOf A-beta-40 secretion,reduced
R11 T15 T14 ThemeOf N-terminally truncated A-beta,increase