OMIM_GOF@xiajingbo:104760-12-APP
Annnotations
AGAC-2-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 142-176 | Var | denotes | val715-to-met (V715M) substitution |
T10 | 358-372 | Var | denotes | V715M mutation |
T11 | 387-394 | NegReg | denotes | reduced |
T12 | 395-414 | MPA | denotes | A-beta-40 secretion |
T13 | 489-497 | PosReg | denotes | increase |
T14 | 501-552 | MPA | denotes | N-terminally truncated A-beta ending at position 42 |
T15 | 713-722 | NegReg | denotes | reduction |
T16 | 738-758 | MPA | denotes | production of A-beta |
T17 | 781-790 | PosReg | denotes | increased |
T18 | 791-852 | MPA | denotes | production of truncated forms of A-beta ending at position 42 |
T2 | 101-109 | Var | denotes | mutation |
T3 | 117-120 | Gene | denotes | APP |
T4 | 127-139 | Reg | denotes | resulting in |
T5 | 196-201 | Var | denotes | V715M |
T6 | 243-250 | NegReg | denotes | reduced |
T7 | 257-274 | MPA | denotes | A-beta production |
T8 | 279-288 | PosReg | denotes | increased |
T9 | 293-352 | MPA | denotes | recovery of the physiologically secreted product, APP-alpha |
R8 | T10 | T11 | CauseOf | V715M mutation,reduced |
R9 | T12 | T11 | ThemeOf | A-beta-40 secretion,reduced |
R1 | T3 | T2 | ThemeOf | APP,mutation |
R11 | T14 | T13 | ThemeOf | N-terminally truncated A-beta ending at position 42,increase |
R12 | T16 | T15 | ThemeOf | production of A-beta,reduction |
R13 | T18 | T17 | ThemeOf | production of truncated forms of A-beta ending at position 42,increased |
R2 | T2 | T4 | CauseOf | mutation,resulting in |
R3 | T1 | T4 | ThemeOf | val715-to-met (V715M) substitution,resulting in |
R4 | T5 | T6 | CauseOf | V715M,reduced |
R5 | T7 | T6 | ThemeOf | A-beta production,reduced |
R6 | T5 | T8 | CauseOf | V715M,increased |
R7 | T9 | T8 | ThemeOf | "recovery of the physiologically secreted product, APP-alpha",increased |
AGAC-2-1
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 142-176 | Var | denotes | val715-to-met (V715M) substitution |
T2 | 117-120 | Gene | denotes | APP |
T3 | 127-139 | Reg | denotes | resulting in |
T4 | 101-109 | Var | denotes | mutation |
T5 | 196-201 | Var | denotes | V715M |
T6 | 178-192 | PosReg | denotes | Overexpression |
T7 | 243-250 | NegReg | denotes | reduced |
T8 | 257-274 | MPA | denotes | A-beta production |
T9 | 279-288 | PosReg | denotes | increased |
T10 | 293-341 | MPA | denotes | recovery of the physiologically secreted product |
T11 | 358-372 | Var | denotes | V715M mutation |
T12 | 387-394 | NegReg | denotes | reduced |
T13 | 395-414 | MPA | denotes | A-beta-40 secretion |
T14 | 489-497 | PosReg | denotes | increase |
T15 | 501-530 | MPA | denotes | N-terminally truncated A-beta |
R1 | T2 | T4 | ThemeOf | APP,mutation |
R2 | T4 | T3 | CauseOf | mutation,resulting in |
R3 | T1 | T3 | ThemeOf | val715-to-met (V715M) substitution,resulting in |
R4 | T5 | T6 | ThemeOf | V715M,Overexpression |
R5 | T6 | T7 | CauseOf | Overexpression,reduced |
R6 | T8 | T7 | ThemeOf | A-beta production,reduced |
R7 | T6 | T9 | CauseOf | Overexpression,increased |
R8 | T10 | T9 | ThemeOf | recovery of the physiologically secreted product,increased |
R9 | T11 | T12 | CauseOf | V715M mutation,reduced |
R10 | T13 | T12 | ThemeOf | A-beta-40 secretion,reduced |
R11 | T15 | T14 | ThemeOf | N-terminally truncated A-beta,increase |