OMIM_GOF@xiajingbo:104311-20-PSEN1 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	32-132	Var	denotes	cys92-to-ser (C92S), the PS1 homolog of the C. elegans sel-12 loss of function mutation cys60 to ser
T2	134-143	PosReg	denotes	increased
T3	144-170	MPA	denotes	amyloid beta-42 production
T4	435-463	Var	denotes	all FAD-linked PS1 mutations
T5	474-483	PosReg	denotes	increased
T6	484-510	MPA	denotes	amyloid beta-42 production
T8	521-533	NegReg	denotes	partial loss
T9	537-555	MPA	denotes	function mechanism
R1	T1	T2	CauseOf	"cys92-to-ser (C92S), the PS1 homolog of the C. elegans sel-12 loss of function mutation cys60 to ser",increased
R2	T3	T2	ThemeOf	amyloid beta-42 production,increased
R3	T4	T5	CauseOf	all FAD-linked PS1 mutations,increased
R4	T6	T5	ThemeOf	amyloid beta-42 production,increased
R5	T4	T8	CauseOf	all FAD-linked PS1 mutations,partial loss
R6	T9	T8	ThemeOf	function mechanism,partial loss

Id	Subject	Object	Predicate	Lexical cue
T1	76-132	Var	denotes	C. elegans sel-12 loss of function mutation cys60 to ser
T2	134-143	PosReg	denotes	increased
T3	144-170	MPA	denotes	amyloid beta-42 production
T4	242-255	Var	denotes	PS1 mutations
T5	439-463	Var	denotes	FAD-linked PS1 mutations
T6	474-483	PosReg	denotes	increased
T7	484-510	MPA	denotes	amyloid beta-42 production
T8	529-545	NegReg	denotes	loss of function
T9	546-555	MPA	denotes	mechanism
R1	T1	T2	CauseOf	C. elegans sel-12 loss of function mutation cys60 to ser,increased
R2	T3	T2	ThemeOf	amyloid beta-42 production,increased
R4	T7	T6	ThemeOf	amyloid beta-42 production,increased
R5	T5	T8	CauseOf	FAD-linked PS1 mutations,loss of function
R6	T9	T8	ThemeOf	mechanism,loss of function
R7	T8	T6	CauseOf	loss of function,increased