CORD-19:932bcdd2f6c6d487386e8bf983e4874387771be1 / 991153-991533 JSONTXT

{"project":"CORD-19-Sentences","denotations":[{"id":"T28218","span":{"begin":0,"end":380},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We have proposed a new hypothesis that chronic autoimmune diseases occur in individuals genetically susceptible to the effects of B-cell infection by EBV, with a resultant increase in the frequency of EBV-infected autoreactive B cells, which not only produce autoantibodies but also inhibit activation-induced apoptosis of autoreactive T cells in the target organ [Trends Immunol."}

{"project":"Epistemic_Statements","denotations":[{"id":"T2002","span":{"begin":0,"end":380},"obj":"Epistemic_statement"}],"text":"We have proposed a new hypothesis that chronic autoimmune diseases occur in individuals genetically susceptible to the effects of B-cell infection by EBV, with a resultant increase in the frequency of EBV-infected autoreactive B cells, which not only produce autoantibodies but also inhibit activation-induced apoptosis of autoreactive T cells in the target organ [Trends Immunol."}

{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T308","span":{"begin":0,"end":380},"obj":"Sentence"}],"text":"We have proposed a new hypothesis that chronic autoimmune diseases occur in individuals genetically susceptible to the effects of B-cell infection by EBV, with a resultant increase in the frequency of EBV-infected autoreactive B cells, which not only produce autoantibodies but also inhibit activation-induced apoptosis of autoreactive T cells in the target organ [Trends Immunol."}

{"project":"CORD-19-PD-HP","denotations":[{"id":"T2080","span":{"begin":47,"end":66},"obj":"Phenotype"}],"attributes":[{"id":"A2080","pred":"hp_id","subj":"T2080","obj":"http://purl.obolibrary.org/obo/HP_0002960"}],"text":"We have proposed a new hypothesis that chronic autoimmune diseases occur in individuals genetically susceptible to the effects of B-cell infection by EBV, with a resultant increase in the frequency of EBV-infected autoreactive B cells, which not only produce autoantibodies but also inhibit activation-induced apoptosis of autoreactive T cells in the target organ [Trends Immunol."}

{"project":"CORD-19-PD-UBERON","denotations":[{"id":"T3040","span":{"begin":358,"end":363},"obj":"Body_part"}],"attributes":[{"id":"A3040","pred":"uberon_id","subj":"T3040","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"}],"text":"We have proposed a new hypothesis that chronic autoimmune diseases occur in individuals genetically susceptible to the effects of B-cell infection by EBV, with a resultant increase in the frequency of EBV-infected autoreactive B cells, which not only produce autoantibodies but also inhibit activation-induced apoptosis of autoreactive T cells in the target organ [Trends Immunol."}

{"project":"CORD-19-PD-MONDO","denotations":[{"id":"T6130","span":{"begin":47,"end":66},"obj":"Disease"},{"id":"T6131","span":{"begin":137,"end":146},"obj":"Disease"},{"id":"T17871","span":{"begin":47,"end":66},"obj":"Disease"},{"id":"T76459","span":{"begin":137,"end":146},"obj":"Disease"}],"attributes":[{"id":"A6130","pred":"mondo_id","subj":"T6130","obj":"http://purl.obolibrary.org/obo/MONDO_0007179"},{"id":"A6131","pred":"mondo_id","subj":"T6131","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A60716","pred":"mondo_id","subj":"T17871","obj":"http://purl.obolibrary.org/obo/MONDO_0007179"},{"id":"A48830","pred":"mondo_id","subj":"T76459","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"We have proposed a new hypothesis that chronic autoimmune diseases occur in individuals genetically susceptible to the effects of B-cell infection by EBV, with a resultant increase in the frequency of EBV-infected autoreactive B cells, which not only produce autoantibodies but also inhibit activation-induced apoptosis of autoreactive T cells in the target organ [Trends Immunol."}