CORD-19:932bcdd2f6c6d487386e8bf983e4874387771be1 / 43323-43793 JSONTXT

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T290","span":{"begin":0,"end":271},"obj":"Sentence"},{"id":"TextSentencer_T291","span":{"begin":272,"end":470},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"This pathway appears to be crucial in regulating oligodendrocyte death and survival as most of the factors aimed at protecting oligodendroglial cells from apoptosis (either neurotrophic factors or antioxydant molecules) require the direct or indirect activation of PI3-K. We have further analyzed the oligodendroglial expression of two G-protein coupled receptor named Edg2/LPA1 and Edg-8/S1P5 activated respectively by lysophosphatidic acid and sphingosine-1-phosphate."}

{"project":"Epistemic_Statements","denotations":[{"id":"T105","span":{"begin":0,"end":470},"obj":"Epistemic_statement"}],"text":"This pathway appears to be crucial in regulating oligodendrocyte death and survival as most of the factors aimed at protecting oligodendroglial cells from apoptosis (either neurotrophic factors or antioxydant molecules) require the direct or indirect activation of PI3-K. We have further analyzed the oligodendroglial expression of two G-protein coupled receptor named Edg2/LPA1 and Edg-8/S1P5 activated respectively by lysophosphatidic acid and sphingosine-1-phosphate."}

{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T290","span":{"begin":0,"end":271},"obj":"Sentence"},{"id":"T291","span":{"begin":272,"end":470},"obj":"Sentence"}],"text":"This pathway appears to be crucial in regulating oligodendrocyte death and survival as most of the factors aimed at protecting oligodendroglial cells from apoptosis (either neurotrophic factors or antioxydant molecules) require the direct or indirect activation of PI3-K. We have further analyzed the oligodendroglial expression of two G-protein coupled receptor named Edg2/LPA1 and Edg-8/S1P5 activated respectively by lysophosphatidic acid and sphingosine-1-phosphate."}