CORD-19:932bcdd2f6c6d487386e8bf983e4874387771be1 / 1022125-1022457
Annnotations
CORD-19-PD-UBERON
As skewed usage of the TCRVh chain CDR3 segment is a marker of antigen-driven expansion, the expansions allowed identification and separation by monoclonal Abs and magnetic microbeads, of a CSF T-cell subpopulation that should be enriched of Ag specific cells and allow generation at high frequency of CNS Ag-specific T cell clones.
CORD-19_Custom_license_subset
As skewed usage of the TCRVh chain CDR3 segment is a marker of antigen-driven expansion, the expansions allowed identification and separation by monoclonal Abs and magnetic microbeads, of a CSF T-cell subpopulation that should be enriched of Ag specific cells and allow generation at high frequency of CNS Ag-specific T cell clones.
CORD-19-Sentences
As skewed usage of the TCRVh chain CDR3 segment is a marker of antigen-driven expansion, the expansions allowed identification and separation by monoclonal Abs and magnetic microbeads, of a CSF T-cell subpopulation that should be enriched of Ag specific cells and allow generation at high frequency of CNS Ag-specific T cell clones.
Epistemic_Statements
As skewed usage of the TCRVh chain CDR3 segment is a marker of antigen-driven expansion, the expansions allowed identification and separation by monoclonal Abs and magnetic microbeads, of a CSF T-cell subpopulation that should be enriched of Ag specific cells and allow generation at high frequency of CNS Ag-specific T cell clones.