CORD-19:68a7101a90454172c91785d8c352f776a82df5d4 / 561832-562147 JSONTXT

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    CORD-19-Sentences

    {"project":"CORD-19-Sentences","denotations":[{"id":"T74146","span":{"begin":0,"end":315},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We demonstrate that whereas the conjugated A-beta-HSP vaccine promoted a very mild T-cell response in a humanized mouse model of AD carrying the DR-DRB1*1501 allele, the humoral response was sufficient to promote a significant reduction of cerebral amyloid burden as well as of the associated inflammatory response."}

    CORD-19_Custom_license_subset

    {"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T106","span":{"begin":0,"end":315},"obj":"Sentence"}],"text":"We demonstrate that whereas the conjugated A-beta-HSP vaccine promoted a very mild T-cell response in a humanized mouse model of AD carrying the DR-DRB1*1501 allele, the humoral response was sufficient to promote a significant reduction of cerebral amyloid burden as well as of the associated inflammatory response."}

    CORD-19-PD-HP

    {"project":"CORD-19-PD-HP","denotations":[{"id":"T1227","span":{"begin":129,"end":131},"obj":"Phenotype"}],"attributes":[{"id":"A1227","pred":"hp_id","subj":"T1227","obj":"http://purl.obolibrary.org/obo/HP_0002511"}],"text":"We demonstrate that whereas the conjugated A-beta-HSP vaccine promoted a very mild T-cell response in a humanized mouse model of AD carrying the DR-DRB1*1501 allele, the humoral response was sufficient to promote a significant reduction of cerebral amyloid burden as well as of the associated inflammatory response."}

    CORD-19-PD-MONDO

    {"project":"CORD-19-PD-MONDO","denotations":[{"id":"T3521","span":{"begin":50,"end":53},"obj":"Disease"},{"id":"T3523","span":{"begin":129,"end":131},"obj":"Disease"},{"id":"T3524","span":{"begin":249,"end":256},"obj":"Disease"},{"id":"T3499","span":{"begin":50,"end":53},"obj":"Disease"},{"id":"T91779","span":{"begin":129,"end":131},"obj":"Disease"},{"id":"T3502","span":{"begin":249,"end":256},"obj":"Disease"}],"attributes":[{"id":"A3521","pred":"mondo_id","subj":"T3521","obj":"http://purl.obolibrary.org/obo/MONDO_0006785"},{"id":"A45925","pred":"mondo_id","subj":"T3521","obj":"http://purl.obolibrary.org/obo/MONDO_0019064"},{"id":"A3523","pred":"mondo_id","subj":"T3523","obj":"http://purl.obolibrary.org/obo/MONDO_0004975"},{"id":"A3524","pred":"mondo_id","subj":"T3524","obj":"http://purl.obolibrary.org/obo/MONDO_0019065"},{"id":"A29023","pred":"mondo_id","subj":"T3499","obj":"http://purl.obolibrary.org/obo/MONDO_0006785"},{"id":"A19248","pred":"mondo_id","subj":"T3499","obj":"http://purl.obolibrary.org/obo/MONDO_0019064"},{"id":"A36669","pred":"mondo_id","subj":"T91779","obj":"http://purl.obolibrary.org/obo/MONDO_0004975"},{"id":"A33962","pred":"mondo_id","subj":"T3502","obj":"http://purl.obolibrary.org/obo/MONDO_0019065"}],"text":"We demonstrate that whereas the conjugated A-beta-HSP vaccine promoted a very mild T-cell response in a humanized mouse model of AD carrying the DR-DRB1*1501 allele, the humoral response was sufficient to promote a significant reduction of cerebral amyloid burden as well as of the associated inflammatory response."}