CORD-19:58c67994f47dc6c8b552cff7de2892719259ec52 / 24678-25053 JSONTXT

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T155","span":{"begin":0,"end":375},"obj":"Sentence"},{"id":"TextSentencer_T155","span":{"begin":0,"end":375},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"20, 21 Second, the unstructured protein molecule can have a greater capture radius for a specific binding site than that of the folded state with its restricted conformational freedom, the so-called \"fly-casting mechanism.\" 22 In this binding scenario, the unfolded state binds weakly at a relatively large distance, and then folds as the protein approaches the binding site."}

{"project":"Epistemic_Statements","denotations":[{"id":"T50","span":{"begin":0,"end":223},"obj":"Epistemic_statement"}],"text":"20, 21 Second, the unstructured protein molecule can have a greater capture radius for a specific binding site than that of the folded state with its restricted conformational freedom, the so-called \"fly-casting mechanism.\" 22 In this binding scenario, the unfolded state binds weakly at a relatively large distance, and then folds as the protein approaches the binding site."}

{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T155","span":{"begin":0,"end":375},"obj":"Sentence"}],"text":"20, 21 Second, the unstructured protein molecule can have a greater capture radius for a specific binding site than that of the folded state with its restricted conformational freedom, the so-called \"fly-casting mechanism.\" 22 In this binding scenario, the unfolded state binds weakly at a relatively large distance, and then folds as the protein approaches the binding site."}