CORD-19:4ca5d854d3f99440b507fd7dfae73c8ad6fc45d5 / 407540-408066 JSONTXT

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{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T217","span":{"begin":0,"end":526},"obj":"Sentence"}],"text":"The alternative Sigma factor B modulates virulence gene expression in a murine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host RT-qPCR of mixed eukaryotic and prokaryotic RNA from infected tissue resulted in the detection of SigB-dependent higher expression levels of asp23 and clfA in the wild type strain S. aureus RN1HG, whereas, in agreement with in vitro data, expression of hla and aur was higher in kidney tissue from animals infected with the sigB mutant strain."}

{"project":"CORD-19-PD-UBERON","denotations":[{"id":"T382","span":{"begin":140,"end":146},"obj":"Body_part"},{"id":"T383","span":{"begin":245,"end":251},"obj":"Body_part"},{"id":"T384","span":{"begin":462,"end":468},"obj":"Body_part"},{"id":"T385","span":{"begin":469,"end":475},"obj":"Body_part"}],"attributes":[{"id":"A382","pred":"uberon_id","subj":"T382","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A383","pred":"uberon_id","subj":"T383","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"id":"A384","pred":"uberon_id","subj":"T384","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A385","pred":"uberon_id","subj":"T385","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"}],"text":"The alternative Sigma factor B modulates virulence gene expression in a murine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host RT-qPCR of mixed eukaryotic and prokaryotic RNA from infected tissue resulted in the detection of SigB-dependent higher expression levels of asp23 and clfA in the wild type strain S. aureus RN1HG, whereas, in agreement with in vitro data, expression of hla and aur was higher in kidney tissue from animals infected with the sigB mutant strain."}

{"project":"CORD-19-PD-MONDO","denotations":[{"id":"T1254","span":{"begin":79,"end":110},"obj":"Disease"},{"id":"T1255","span":{"begin":101,"end":110},"obj":"Disease"},{"id":"T28127","span":{"begin":79,"end":110},"obj":"Disease"},{"id":"T59469","span":{"begin":101,"end":110},"obj":"Disease"}],"attributes":[{"id":"A1254","pred":"mondo_id","subj":"T1254","obj":"http://purl.obolibrary.org/obo/MONDO_0005545"},{"id":"A1255","pred":"mondo_id","subj":"T1255","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A44907","pred":"mondo_id","subj":"T28127","obj":"http://purl.obolibrary.org/obo/MONDO_0005545"},{"id":"A54515","pred":"mondo_id","subj":"T59469","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"The alternative Sigma factor B modulates virulence gene expression in a murine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host RT-qPCR of mixed eukaryotic and prokaryotic RNA from infected tissue resulted in the detection of SigB-dependent higher expression levels of asp23 and clfA in the wild type strain S. aureus RN1HG, whereas, in agreement with in vitro data, expression of hla and aur was higher in kidney tissue from animals infected with the sigB mutant strain."}