CORD-19:35349bb1fc9290338907b7d7f104c9db3951163b / 147890-148230 JSONTXT

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T1098","span":{"begin":0,"end":340},"obj":"Sentence"},{"id":"T12936","span":{"begin":0,"end":340},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Despite studies demonstrating that lower doses of toceranib (2.4 -2.9 mg/kg every other day) provides drug exposure sufficient for target inhibition while reducing the frequency of drug-related adverse events, gastrointestinal (GI) toxicity continues to be the most commonly encountered side effect in dogs receiving toceranib at this dose."}