CORD-19:16a812de72963ceda960a168236e8dbe91832d45 / 61510-61771 JSONTXT

{"project":"CORD-19-SciBite-sentences","denotations":[{"id":"T700","span":{"begin":0,"end":261},"obj":"https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL2074865"},{"id":"T708","span":{"begin":0,"end":261},"obj":"http://purl.obolibrary.org/obo/HP0025464"},{"id":"T711","span":{"begin":0,"end":261},"obj":"http://purl.obolibrary.org/obo/GO0008219"},{"id":"T713","span":{"begin":0,"end":261},"obj":"http://purl.obolibrary.org/obo/GO0006915"},{"id":"T715","span":{"begin":0,"end":261},"obj":"http://purl.obolibrary.org/obo/GO0045121"}],"attributes":[{"id":"A700","pred":"class","subj":"T700","obj":"DRUG"},{"id":"A708","pred":"class","subj":"T708","obj":"HPO"},{"id":"A711","pred":"class","subj":"T711","obj":"GOONTOL"},{"id":"A713","pred":"class","subj":"T713","obj":"GOONTOL"},{"id":"A715","pred":"class","subj":"T715","obj":"GOONTOL"}],"text":"Cholesterol chelation with methyl-β-cyclodextrin (β-MCD) completely abrogates the protective effect of rHIgM22, suggesting that signaling from lipid rafts is critical for the ability of rHIgM22 to rescue oligodendrocytes from oxidative stress-induced apoptosis."}

{"project":"Epistemic_Statements","denotations":[{"id":"T133","span":{"begin":0,"end":261},"obj":"Epistemic_statement"}],"text":"Cholesterol chelation with methyl-β-cyclodextrin (β-MCD) completely abrogates the protective effect of rHIgM22, suggesting that signaling from lipid rafts is critical for the ability of rHIgM22 to rescue oligodendrocytes from oxidative stress-induced apoptosis."}

{"project":"CORD-19-PD-MONDO","denotations":[{"id":"T184","span":{"begin":52,"end":55},"obj":"Disease"}],"attributes":[{"id":"A184","pred":"mondo_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/MONDO_0009020"},{"id":"A185","pred":"mondo_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/MONDO_0015454"},{"id":"A186","pred":"mondo_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/MONDO_0019754"}],"text":"Cholesterol chelation with methyl-β-cyclodextrin (β-MCD) completely abrogates the protective effect of rHIgM22, suggesting that signaling from lipid rafts is critical for the ability of rHIgM22 to rescue oligodendrocytes from oxidative stress-induced apoptosis."}

{"project":"CORD-19-PD-HP","denotations":[{"id":"T91","span":{"begin":226,"end":242},"obj":"Phenotype"}],"attributes":[{"id":"A91","pred":"hp_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/HP_0025464"}],"text":"Cholesterol chelation with methyl-β-cyclodextrin (β-MCD) completely abrogates the protective effect of rHIgM22, suggesting that signaling from lipid rafts is critical for the ability of rHIgM22 to rescue oligodendrocytes from oxidative stress-induced apoptosis."}