CORD-19:16a812de72963ceda960a168236e8dbe91832d45 / 55353-55784 JSONTXT

{"project":"CORD-19-SciBite-sentences","denotations":[{"id":"T618","span":{"begin":0,"end":431},"obj":"http://purl.obolibrary.org/obo/GO0005622"},{"id":"T619","span":{"begin":0,"end":431},"obj":"http://purl.obolibrary.org/obo/GO0032281"},{"id":"T621","span":{"begin":0,"end":431},"obj":"http://purl.obolibrary.org/obo/GO0019722"},{"id":"T622","span":{"begin":0,"end":431},"obj":"http://purl.obolibrary.org/obo/GO0005576"}],"attributes":[{"id":"A618","pred":"class","subj":"T618","obj":"GOONTOL"},{"id":"A619","pred":"class","subj":"T619","obj":"GOONTOL"},{"id":"A621","pred":"class","subj":"T621","obj":"GOONTOL"},{"id":"A622","pred":"class","subj":"T622","obj":"GOONTOL"}],"text":"Further evidence in support of a causal link between calcium signaling and remyelination is provided by experiments showing that rHIgM22 elicits a transient elevation in intracellular calcium in CG4 cells, a model of premyelinating oligodendrocytes (Howe et al., 2004) . As with primary oligodendrocytes, we found that this calcium signal was dependent on the influx of extracellular calcium through AMPA receptor calcium channels."}

{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T37","span":{"begin":0,"end":270},"obj":"Sentence"},{"id":"T38","span":{"begin":271,"end":431},"obj":"Sentence"}],"text":"Further evidence in support of a causal link between calcium signaling and remyelination is provided by experiments showing that rHIgM22 elicits a transient elevation in intracellular calcium in CG4 cells, a model of premyelinating oligodendrocytes (Howe et al., 2004) . As with primary oligodendrocytes, we found that this calcium signal was dependent on the influx of extracellular calcium through AMPA receptor calcium channels."}

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T279","span":{"begin":0,"end":270},"obj":"Sentence"},{"id":"TextSentencer_T280","span":{"begin":271,"end":431},"obj":"Sentence"},{"id":"TextSentencer_T279","span":{"begin":0,"end":270},"obj":"Sentence"},{"id":"TextSentencer_T280","span":{"begin":271,"end":431},"obj":"Sentence"},{"id":"T44527","span":{"begin":0,"end":270},"obj":"Sentence"},{"id":"T86116","span":{"begin":271,"end":431},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Further evidence in support of a causal link between calcium signaling and remyelination is provided by experiments showing that rHIgM22 elicits a transient elevation in intracellular calcium in CG4 cells, a model of premyelinating oligodendrocytes (Howe et al., 2004) . As with primary oligodendrocytes, we found that this calcium signal was dependent on the influx of extracellular calcium through AMPA receptor calcium channels."}

{"project":"Epistemic_Statements","denotations":[{"id":"T124","span":{"begin":0,"end":270},"obj":"Epistemic_statement"}],"text":"Further evidence in support of a causal link between calcium signaling and remyelination is provided by experiments showing that rHIgM22 elicits a transient elevation in intracellular calcium in CG4 cells, a model of premyelinating oligodendrocytes (Howe et al., 2004) . As with primary oligodendrocytes, we found that this calcium signal was dependent on the influx of extracellular calcium through AMPA receptor calcium channels."}

{"project":"CORD-19-PD-MONDO","denotations":[{"id":"T179","span":{"begin":339,"end":342},"obj":"Disease"}],"attributes":[{"id":"A179","pred":"mondo_id","subj":"T179","obj":"http://purl.obolibrary.org/obo/MONDO_0010518"}],"text":"Further evidence in support of a causal link between calcium signaling and remyelination is provided by experiments showing that rHIgM22 elicits a transient elevation in intracellular calcium in CG4 cells, a model of premyelinating oligodendrocytes (Howe et al., 2004) . As with primary oligodendrocytes, we found that this calcium signal was dependent on the influx of extracellular calcium through AMPA receptor calcium channels."}