CORD-19:16a812de72963ceda960a168236e8dbe91832d45 / 26269-26628 JSONTXT

{"project":"CORD-19-SciBite-sentences","denotations":[{"id":"T299","span":{"begin":0,"end":359},"obj":"http://www.genenames.org/cgi-bin/gene_symbol_report?match=PRF1"},{"id":"T305","span":{"begin":0,"end":359},"obj":"http://purl.obolibrary.org/obo/HP0011096"},{"id":"T310","span":{"begin":0,"end":359},"obj":"https://id.nlm.nih.gov/mesh/D017945"},{"id":"T311","span":{"begin":0,"end":359},"obj":"https://id.nlm.nih.gov/mesh/D014780"},{"id":"T312","span":{"begin":0,"end":359},"obj":"DSPEC000027"},{"id":"T315","span":{"begin":0,"end":359},"obj":"https://id.nlm.nih.gov/mesh/D051379"},{"id":"T323","span":{"begin":0,"end":359},"obj":"https://id.nlm.nih.gov/mesh/D014777"},{"id":"T325","span":{"begin":0,"end":359},"obj":"https://id.nlm.nih.gov/mesh/D017945"},{"id":"T326","span":{"begin":0,"end":359},"obj":"https://id.nlm.nih.gov/mesh/D003711"},{"id":"T330","span":{"begin":0,"end":359},"obj":"https://id.nlm.nih.gov/mesh/D009461"}],"attributes":[{"id":"A305","pred":"class","subj":"T305","obj":"HPO"},{"id":"A312","pred":"class","subj":"T312","obj":"SPECIES"},{"id":"A311","pred":"class","subj":"T311","obj":"SPECIES"},{"id":"A325","pred":"class","subj":"T325","obj":"INDICATION"},{"id":"A330","pred":"class","subj":"T330","obj":"INDICATION"},{"id":"A323","pred":"class","subj":"T323","obj":"INDICATION"},{"id":"A326","pred":"class","subj":"T326","obj":"INDICATION"},{"id":"A310","pred":"class","subj":"T310","obj":"SPECIES"},{"id":"A299","pred":"class","subj":"T299","obj":"GENE"},{"id":"A315","pred":"class","subj":"T315","obj":"SPECIES"}],"text":"Our laboratory has demonstrated, using Theiler's virus infection of C57BL/6 H-2 b mice, that perforin may be a critical component in the induction of neurological deficits once demyelination is established (Murray et al., 1998) . We found that perforin deficiency broke viral resistance, resulting in viral persistence and consequent demyelination (Fig. 15 )."}

{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T134","span":{"begin":0,"end":229},"obj":"Sentence"},{"id":"T135","span":{"begin":230,"end":359},"obj":"Sentence"}],"text":"Our laboratory has demonstrated, using Theiler's virus infection of C57BL/6 H-2 b mice, that perforin may be a critical component in the induction of neurological deficits once demyelination is established (Murray et al., 1998) . We found that perforin deficiency broke viral resistance, resulting in viral persistence and consequent demyelination (Fig. 15 )."}

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T134","span":{"begin":0,"end":229},"obj":"Sentence"},{"id":"TextSentencer_T135","span":{"begin":230,"end":359},"obj":"Sentence"},{"id":"TextSentencer_T134","span":{"begin":0,"end":229},"obj":"Sentence"},{"id":"TextSentencer_T135","span":{"begin":230,"end":359},"obj":"Sentence"},{"id":"T53261","span":{"begin":0,"end":229},"obj":"Sentence"},{"id":"T42218","span":{"begin":230,"end":359},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Our laboratory has demonstrated, using Theiler's virus infection of C57BL/6 H-2 b mice, that perforin may be a critical component in the induction of neurological deficits once demyelination is established (Murray et al., 1998) . We found that perforin deficiency broke viral resistance, resulting in viral persistence and consequent demyelination (Fig. 15 )."}

{"project":"Epistemic_Statements","denotations":[{"id":"T64","span":{"begin":0,"end":229},"obj":"Epistemic_statement"}],"text":"Our laboratory has demonstrated, using Theiler's virus infection of C57BL/6 H-2 b mice, that perforin may be a critical component in the induction of neurological deficits once demyelination is established (Murray et al., 1998) . We found that perforin deficiency broke viral resistance, resulting in viral persistence and consequent demyelination (Fig. 15 )."}

{"project":"CORD-19-PD-MONDO","denotations":[{"id":"T93","span":{"begin":49,"end":64},"obj":"Disease"},{"id":"T94","span":{"begin":55,"end":64},"obj":"Disease"}],"attributes":[{"id":"A93","pred":"mondo_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A94","pred":"mondo_id","subj":"T94","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Our laboratory has demonstrated, using Theiler's virus infection of C57BL/6 H-2 b mice, that perforin may be a critical component in the induction of neurological deficits once demyelination is established (Murray et al., 1998) . We found that perforin deficiency broke viral resistance, resulting in viral persistence and consequent demyelination (Fig. 15 )."}

{"project":"CORD-19-PD-HP","denotations":[{"id":"T59","span":{"begin":177,"end":190},"obj":"Phenotype"},{"id":"T60","span":{"begin":334,"end":347},"obj":"Phenotype"}],"attributes":[{"id":"A59","pred":"hp_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/HP_0011096"},{"id":"A60","pred":"hp_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/HP_0011096"}],"text":"Our laboratory has demonstrated, using Theiler's virus infection of C57BL/6 H-2 b mice, that perforin may be a critical component in the induction of neurological deficits once demyelination is established (Murray et al., 1998) . We found that perforin deficiency broke viral resistance, resulting in viral persistence and consequent demyelination (Fig. 15 )."}