CORD-19:120bd6eed7e254029455aec25478a4860a46764e / 157813-158251 JSONTXT

{"project":"CORD-19-SciBite-sentences","denotations":[{"id":"T2621","span":{"begin":0,"end":438},"obj":"http://www.genenames.org/cgi-bin/gene_symbol_report?match=RB1"},{"id":"T2623","span":{"begin":0,"end":438},"obj":"http://www.genenames.org/cgi-bin/gene_symbol_report?match=CDK4"},{"id":"T2624","span":{"begin":0,"end":438},"obj":"http://purl.obolibrary.org/obo/HP0009919"},{"id":"T2628","span":{"begin":0,"end":438},"obj":"http://purl.obolibrary.org/obo/GO0006351"},{"id":"T2634","span":{"begin":0,"end":438},"obj":"http://purl.obolibrary.org/obo/GO0040007"},{"id":"T2639","span":{"begin":0,"end":438},"obj":"http://purl.obolibrary.org/obo/GO0005576"},{"id":"T2640","span":{"begin":0,"end":438},"obj":"http://purl.obolibrary.org/obo/GO0016310"},{"id":"T2644","span":{"begin":0,"end":438},"obj":"http://purl.obolibrary.org/obo/GO0016538"},{"id":"T2645","span":{"begin":0,"end":438},"obj":"http://purl.obolibrary.org/obo/GO0010467"},{"id":"T2647","span":{"begin":0,"end":438},"obj":"https://id.nlm.nih.gov/mesh/D012175"}],"attributes":[{"id":"A2639","pred":"class","subj":"T2639","obj":"GOONTOL"},{"id":"A2647","pred":"class","subj":"T2647","obj":"INDICATION"},{"id":"A2634","pred":"class","subj":"T2634","obj":"GOONTOL"},{"id":"A2645","pred":"class","subj":"T2645","obj":"GOONTOL"},{"id":"A2623","pred":"class","subj":"T2623","obj":"GENE"},{"id":"A2621","pred":"class","subj":"T2621","obj":"GENE"},{"id":"A2624","pred":"class","subj":"T2624","obj":"HPO"},{"id":"A2640","pred":"class","subj":"T2640","obj":"GOONTOL"},{"id":"A2628","pred":"class","subj":"T2628","obj":"GOONTOL"},{"id":"A2644","pred":"class","subj":"T2644","obj":"GOONTOL"}],"text":"Cells enter G 1 in response to growth factors that also cause the sequential accumulation of cyclins whose roles are to modulate the progress of G 1 . Cyclin D activation of CDK4/6 results in phosphorylation of retinoblastoma (RB) protein, which in turn releases the transcription factor E2F and enables the cell to pass through the so-called restriction point in G 1 , after which the cell is independent of extracellular growth signals."}

{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T66","span":{"begin":0,"end":150},"obj":"Sentence"},{"id":"T67","span":{"begin":151,"end":438},"obj":"Sentence"}],"text":"Cells enter G 1 in response to growth factors that also cause the sequential accumulation of cyclins whose roles are to modulate the progress of G 1 . Cyclin D activation of CDK4/6 results in phosphorylation of retinoblastoma (RB) protein, which in turn releases the transcription factor E2F and enables the cell to pass through the so-called restriction point in G 1 , after which the cell is independent of extracellular growth signals."}

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T1041","span":{"begin":0,"end":150},"obj":"Sentence"},{"id":"TextSentencer_T1042","span":{"begin":151,"end":438},"obj":"Sentence"},{"id":"TextSentencer_T1041","span":{"begin":0,"end":150},"obj":"Sentence"},{"id":"TextSentencer_T1042","span":{"begin":151,"end":438},"obj":"Sentence"},{"id":"T6804","span":{"begin":0,"end":150},"obj":"Sentence"},{"id":"T62771","span":{"begin":151,"end":438},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Cells enter G 1 in response to growth factors that also cause the sequential accumulation of cyclins whose roles are to modulate the progress of G 1 . Cyclin D activation of CDK4/6 results in phosphorylation of retinoblastoma (RB) protein, which in turn releases the transcription factor E2F and enables the cell to pass through the so-called restriction point in G 1 , after which the cell is independent of extracellular growth signals."}

{"project":"CORD-19-PD-MONDO","denotations":[{"id":"T549","span":{"begin":211,"end":225},"obj":"Disease"},{"id":"T550","span":{"begin":227,"end":229},"obj":"Disease"}],"attributes":[{"id":"A549","pred":"mondo_id","subj":"T549","obj":"http://purl.obolibrary.org/obo/MONDO_0008380"},{"id":"A550","pred":"mondo_id","subj":"T550","obj":"http://purl.obolibrary.org/obo/MONDO_0008380"}],"text":"Cells enter G 1 in response to growth factors that also cause the sequential accumulation of cyclins whose roles are to modulate the progress of G 1 . Cyclin D activation of CDK4/6 results in phosphorylation of retinoblastoma (RB) protein, which in turn releases the transcription factor E2F and enables the cell to pass through the so-called restriction point in G 1 , after which the cell is independent of extracellular growth signals."}

{"project":"CORD-19-PD-HP","denotations":[{"id":"T212","span":{"begin":211,"end":225},"obj":"Phenotype"},{"id":"T213","span":{"begin":227,"end":229},"obj":"Phenotype"}],"attributes":[{"id":"A212","pred":"hp_id","subj":"T212","obj":"http://purl.obolibrary.org/obo/HP_0009919"},{"id":"A213","pred":"hp_id","subj":"T213","obj":"http://purl.obolibrary.org/obo/HP_0009919"}],"text":"Cells enter G 1 in response to growth factors that also cause the sequential accumulation of cyclins whose roles are to modulate the progress of G 1 . Cyclin D activation of CDK4/6 results in phosphorylation of retinoblastoma (RB) protein, which in turn releases the transcription factor E2F and enables the cell to pass through the so-called restriction point in G 1 , after which the cell is independent of extracellular growth signals."}