CORD-19:013ce450f63ae2496b92f987e35b55125a43947f / 7340-7830 JSONTXT

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T36","span":{"begin":0,"end":490},"obj":"Sentence"},{"id":"TextSentencer_T36","span":{"begin":0,"end":490},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The SIgA antibodies play a major role in preservation of mucosal integrity by down-regulation of systemic-type immune responses, preventing invasion of pathogens from the mucosa by blocking of attachment or invasion, neutralization (in the lumen or intracellularly), and \"immune exclusion.\" These functions are in contrast to systemically induced IgG antibodies that mediate inflammatory reactions leading to the killing and elimination of pathogens, thereby maintaining systemic sterility."}

{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T36","span":{"begin":0,"end":490},"obj":"Sentence"}],"text":"The SIgA antibodies play a major role in preservation of mucosal integrity by down-regulation of systemic-type immune responses, preventing invasion of pathogens from the mucosa by blocking of attachment or invasion, neutralization (in the lumen or intracellularly), and \"immune exclusion.\" These functions are in contrast to systemically induced IgG antibodies that mediate inflammatory reactions leading to the killing and elimination of pathogens, thereby maintaining systemic sterility."}

{"project":"Epistemic_Statements","denotations":[{"id":"T12","span":{"begin":291,"end":490},"obj":"Epistemic_statement"}],"text":"The SIgA antibodies play a major role in preservation of mucosal integrity by down-regulation of systemic-type immune responses, preventing invasion of pathogens from the mucosa by blocking of attachment or invasion, neutralization (in the lumen or intracellularly), and \"immune exclusion.\" These functions are in contrast to systemically induced IgG antibodies that mediate inflammatory reactions leading to the killing and elimination of pathogens, thereby maintaining systemic sterility."}

{"project":"CORD-19-PD-MONDO","denotations":[{"id":"T23","span":{"begin":480,"end":489},"obj":"Disease"}],"attributes":[{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0005047"}],"text":"The SIgA antibodies play a major role in preservation of mucosal integrity by down-regulation of systemic-type immune responses, preventing invasion of pathogens from the mucosa by blocking of attachment or invasion, neutralization (in the lumen or intracellularly), and \"immune exclusion.\" These functions are in contrast to systemically induced IgG antibodies that mediate inflammatory reactions leading to the killing and elimination of pathogens, thereby maintaining systemic sterility."}

{"project":"CORD-19-PD-UBERON","denotations":[{"id":"T29","span":{"begin":171,"end":177},"obj":"Body_part"}],"attributes":[{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0000344"}],"text":"The SIgA antibodies play a major role in preservation of mucosal integrity by down-regulation of systemic-type immune responses, preventing invasion of pathogens from the mucosa by blocking of attachment or invasion, neutralization (in the lumen or intracellularly), and \"immune exclusion.\" These functions are in contrast to systemically induced IgG antibodies that mediate inflammatory reactions leading to the killing and elimination of pathogens, thereby maintaining systemic sterility."}