CORD-19:0049ba8861864506e1e8559e7815f4de8b03dbed / 3584-3898 JSONTXT

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T27","span":{"begin":0,"end":314},"obj":"Sentence"},{"id":"T43742","span":{"begin":0,"end":314},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Upon interaction with CD4 receptor, a lipid raftassociated protein [15] [16] [17] [18] , on the target cell surface, the native HIV-1 envelope spike goes through extensive conformational changes that allow additional binding to a co-receptor, CXCR4 for T-cell tropic strains or CCR5 for macrophage-tropic isolates."}